To study the curative effect of wil sonii injecta on severe head injury (SHI).Methods: A total of 120 patients with SHI were divided randomly into 2 groups, the patients treated with conventional methods as Group A (n...To study the curative effect of wil sonii injecta on severe head injury (SHI).Methods: A total of 120 patients with SHI were divided randomly into 2 groups, the patients treated with conventional methods as Group A (n=60) and the patients treated with wilsonii injecta as Group B (n=60). The changes o f neural function indexes were evaluated with Glasgow Coma Scale (GCS) before tr eatment and with Glasgow Outcome Scale (GOS) after treatment, simultaneously, th e parameters of hemorrheological indexes (HI), brain electrical activity map (BE AM) and transcranial Doppler sonography (TCD) were observed before and after tre atment.Results: In Group B, the clinical GCS, the HI, the BEAM and the prognosis GOS were improved much more than those in Group A. And the TCD parame ters in Group B decreased, which had significant difference compared with that i n Group A (P< 0.01 ).Conclusions: Wilsonii injecta can rapidly improve the injured p ersons’ conscious states, the abnormal BEAM and the surviving quality. It sugges ts that the improvement of the HI is related to the relief of the vasospasm of the arterial blood vessels in the brain, which may be one of the important mecha nisms of wilsonii injecta in improving the prognosis.展开更多
文摘To study the curative effect of wil sonii injecta on severe head injury (SHI).Methods: A total of 120 patients with SHI were divided randomly into 2 groups, the patients treated with conventional methods as Group A (n=60) and the patients treated with wilsonii injecta as Group B (n=60). The changes o f neural function indexes were evaluated with Glasgow Coma Scale (GCS) before tr eatment and with Glasgow Outcome Scale (GOS) after treatment, simultaneously, th e parameters of hemorrheological indexes (HI), brain electrical activity map (BE AM) and transcranial Doppler sonography (TCD) were observed before and after tre atment.Results: In Group B, the clinical GCS, the HI, the BEAM and the prognosis GOS were improved much more than those in Group A. And the TCD parame ters in Group B decreased, which had significant difference compared with that i n Group A (P< 0.01 ).Conclusions: Wilsonii injecta can rapidly improve the injured p ersons’ conscious states, the abnormal BEAM and the surviving quality. It sugges ts that the improvement of the HI is related to the relief of the vasospasm of the arterial blood vessels in the brain, which may be one of the important mecha nisms of wilsonii injecta in improving the prognosis.
