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Expert consensus on diagnosis and treatment of ulcerative colitis with integrated traditional Chinese and Western medicine:A nursing perspective 被引量:1
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作者 Bing XU Miao LIU +3 位作者 Hairong HU Jing ZHANG Yanping HUANG Ling TANG 《Journal of Integrative Nursing》 2023年第1期1-7,共7页
Ulcerative colitis(UC)is a chronic nonspecific intestinal inflammatory disease of unclear etiology,characterized by continuous and diffuse inflammatory changes of colorectal mucosa.In recent years,the incidence rate o... Ulcerative colitis(UC)is a chronic nonspecific intestinal inflammatory disease of unclear etiology,characterized by continuous and diffuse inflammatory changes of colorectal mucosa.In recent years,the incidence rate of UC in China has increased year by year,but there is no effective cure method in Western medicine.Traditional Chinese medicine treatment based on syndrome differentiation has the unique advantages of simplicity,convenience,effectiveness,and low cost.Therefore,integration of Chinese and Western medicine has become an important strategy for UC diagnosis and treatment,and has made significant progress in UC.On the basis of learning from a number of consensuses at home and abroad,combined with Chinese research results and the actual clinical situation of traditional Chinese and Western medicine,the UC group of the Chinese Association of Integrative Medicine has formulated the expert consensus on the diagnosis and treatment of UC with integrated traditional Chinese and Western medicine.In this consensus,the pathogenesis,etiology and pathogenesis,diagnosis,integrated traditional Chinese and Western medicine treatment,and chronic disease management with integrated traditional Chinese and Western medicine for UC were recommended by experts.This article interprets the consensus from the perspective of nursing in order to provide reference basis for clinical nursing workers. 展开更多
关键词 CONSENSUS continuing care integrated traditional chinese and western medicine nursing nursing perspective traditional chinese medicine ulcerative colitis
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Application of integrated traditional Chinese and Western medicine in the treatment of juvenile localized scleroderma with skin ulcer: a case report
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作者 Jia-Qian Zhang Xiao-Han Wang +3 位作者 Wen-Zhen Tu Li-Ming Chen Qi Kong Yin-Huan Zhao 《Clinical Research Communications》 2023年第3期10-15,共6页
Background:Juvenile Localized Scleroderma(JLS)is a rare pediatric rheumatic disease characterized by inflammation and skin sclerosis.The side effect of consensus-recommended medications and the risk of disability pose... Background:Juvenile Localized Scleroderma(JLS)is a rare pediatric rheumatic disease characterized by inflammation and skin sclerosis.The side effect of consensus-recommended medications and the risk of disability posed challenges to the JLS treatment.We intend to demonstrate the potential of traditional Chinese medicine in treating JLS with skin ulcers and reducing the dose of glucocorticoid.Method:Here we report a case of a 13-year-old male with JLS who took oral methotrexate tablets of 10 mg/week and methylprednisolone of 6 mg/day for over six months without significant effect and suffered from skin ulcers on the dorsal feet one month after drug cessation.Subsequently,the patient was treated with integrated traditional Chinese and Western medicine of low-dose glucocorticosteroid,adjusted Shenqi Huoxue formula and Jinshe Xiaoyan formula,etc.Results:After integrated treatment,the patient’s dorsal feet ulcers healed and the skin sclerosis and hyperpigmentation improved significantly.Conclusions:This case report suggests that integrated traditional Chinese and Western medicine can be used as an effective treatment for JLS. 展开更多
关键词 juvenile localized scleroderma traditional chinese medicine integrated traditional chinese and western medicine skin ulcer case report
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Analysis on the therapeutic effects of integrated traditional Chinese and Western medicine on ulcerative colitis and its effects on coagulation function and inflammatory factors
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作者 Qiong Wang Han-Ting Zhu +1 位作者 Guo-Rong Wu Wen Chen 《Journal of Hainan Medical University》 2019年第1期5-9,共5页
Objective:To analyze the therapeutic effects of Integrated Traditional Chinese and Western Medicine on ulcerative colitis (UC) and its effects on coagulation function and inflammatory factors.Methods: 220 cases of pat... Objective:To analyze the therapeutic effects of Integrated Traditional Chinese and Western Medicine on ulcerative colitis (UC) and its effects on coagulation function and inflammatory factors.Methods: 220 cases of patients with UC were selected as the research subjects and randomly divided into the observation group and the control group, 110 cases were included into each group. The patients in the control group were treated with single western medicine, while the patients in the observation group were treated with enema treatment of traditional Chinese Medicine. The clinical therapeutic effects of the two groups were evaluated and compared. The blood coagulation indexes of the activated partial thromboplastin time (APTT), prothrombin time (PT), the plasma fibrinogen (Fib), the D dimer (D-D) of two groups patients who in the treatment were detected and compared. The serum tumor necrosis factor (TNF-α), interleukin-6 (IL-6), interleukin-8 (IL-8) levels of the patients in the two groups were measured and compared.Results: The clinical efficiencies of the observation group and the control group were 97% and 75%, the clinical efficiencies and the therapeutic effects of the observation group were better than those in the control group, there were statistically significant differences between the two groups. The plasma Fib levels and the plasma D-D levels after the treatment of the patients in the two groups were significantly lower than those before the treatment, the difference was statistically significant. The plasma Fib levels and the plasma D-D levels after the treatment of the patients in the observation group were lower than those in the control group, the difference was statistically significant. The serum inflammatory factors levels after the treatment of the patients in the two groups were significantly lower than those before the treatment, the difference was statistically significant. The serum inflammatory factors levels after the treatment of the patients in the observation group were lower than those in the control group, the difference is powerful and have statistically significant.Conclusion: The application of Integrated Traditional Chinese and Western Medicine in the treatment of UC can improve the therapeutic effect significantly, correct imbalance of the patients' coagulation dissolution function, reduce the degree of inflammatory reaction, which benefits to promote of the patients' rehabilitation, reduce the incidence of complications and improve the prognosis of patients. 展开更多
关键词 integrated chinese and western medicine ulcerATIVE COLITIS Experimental therapy COAGULATION and FIBRINOLYSIS Inflammatory factor
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A Survey on Treatment of Dry Eye by Traditional Chinese Medicine and Integrative Chinese and Western Medicine 被引量:2
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作者 周婉瑜 李越虹 《Chinese Journal of Integrated Traditional and Western Medicine》 2006年第2期154-159,共6页
Dry eye is now one of the most common superficial disorders in ophthalmology at home and abroad, and more and more people attach importance to the study. The ideal approach for treatment of dry eye is to normalize the... Dry eye is now one of the most common superficial disorders in ophthalmology at home and abroad, and more and more people attach importance to the study. The ideal approach for treatment of dry eye is to normalize the condition by rebuilding the superficial circumstance of the eye, and to make tear film work as well as possible so as to relieve the irritating symptoms in the eye. The authors are making a comprehensive discussion on the methods and curative effects of treating dry eye by traditional Chinese medicine and by integrative Chinese and Western medicine in recent years, so as to introduce the distinctive features of the traditional Chinese medicine and integrative Chinese and Western medicine in this field. 展开更多
关键词 dry eye traditional chinese medicine therapy integrative chinese and western medicine therapy
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Clinical Evaluation of Integrative Chinese and Western Medicine in Treating SARS 被引量:2
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作者 李秀惠 张可 +4 位作者 胡建华 郭新会 胡中杰 杨宇 梁连春 《Chinese Journal of Integrated Traditional and Western Medicine》 2003年第3期181-184,共4页
Objective:To evaluate the effective treatment with integrative Chinese and western medicine (ICWM) of severe acute respiratory syndrome (SARS). Methods: The 65 cases of SARS patients were treated with ICWM and 37 case... Objective:To evaluate the effective treatment with integrative Chinese and western medicine (ICWM) of severe acute respiratory syndrome (SARS). Methods: The 65 cases of SARS patients were treated with ICWM and 37 cases with western medicine (WM) alone as the control in our hospital from March 11 to April 30, 2003. The results were analyzed, with T subset profile tested for all the 102 patients. Results: Sixty-five cases of SARS patients treated with ICWM included 52 mild cases of whom 51 cases were cured (98.1%) and no patient died. As to the 13 severe cases in this group, 9 were cured (69. 2%) and 2 died (15. 4%). Of the 37 cases treated with WM alone, 16 out of the 18 common cases were cured (88. 9%) and 10 out of the 19 severe cases were cured (52. 6%), with the other 9 died (47. 4%). Comparison between the two groups (P=0. 061) showed the difference was close to the value for statistical significance. But considering that the number of samples was small, more cases are needed for further study. The immune function examination: in cases of the common type, after ICWM treatment, CD4 + T lymphocytes were increased from 360±247 cell/mm3 to 563±479 cell/mm3 (P<0. 05). In the group treated with WM alone, CD4+ T lymphocytes were increased from 331 ±193 cell/mm3 to 772±354 cell/mm3 (P<0. 05). As to the severe cases after ICWM treatment, CD4+ T lymphocytes increased from 352±279 cell/mm3 to 525±490 cell/mm3 (P>0. 05). In the group of severe cases treated with WM alone, CD4+ T lymphocytes reduced from 229±69 cell/mm3 to 205±108 cell/mm3 (P>0. 05). While after ICWM treatment, CD4+ T lymphocytes were significantly higher than that of the group treated with WM alone (P< 0. 05). Conclusion: Compared with the group treated with WM alone, ICWM can significantly improve the prognosis, reduce the mortality as well as improve the immune function of SARS patients. 展开更多
关键词 integrative chinese and western medicine severe acute respiratory syndrome therapy T lymphocyte subsets
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Analysis of Clinical Evaluation of Response to Treatment of Parkinson's Disease with Integrated Chinese and Western Medicine Therapy 被引量:7
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作者 李敏 杨明会 +3 位作者 刘毅 雒晓东 陈建宗 史恒军 《Chinese Journal of Integrative Medicine》 SCIE CAS CSCD 2015年第1期17-21,共5页
Objective: To analyze the clinical evaluation of Parkinson's disease (PD) patients receiving integrated Chinese and Western medicine therapy. Methods: One hundred and twenty patients were enrolled and randomly al... Objective: To analyze the clinical evaluation of Parkinson's disease (PD) patients receiving integrated Chinese and Western medicine therapy. Methods: One hundred and twenty patients were enrolled and randomly allocated to a control group or treatment group. Patients in the two groups received placebo and Bushen Huoxue Granule (补肾活血颗粒, BHG), respectively. Both groups received baseline levodopa and benserazide (Madopar). The effects of treatment were assessed monthly during the 9-month treatment. Means of evaluation included Unified PD Rating Scale (UPDRS) scores (Ⅱ and Ⅲ), sleep scale score, 10 m turn back test (getting up time, 10 m × 2 times, and turning time), timing motor test (TMT)-Ieft and TMT-right, which were treated as the dependent variables; and age, sex, duration of PD, Hoehn and Yahr (H-Y) stage and Madopar dosage of admitted PD patients were as the independent variables. Multiple linear regression was used to analyze these factors. Results: H-Y stage significantly affected UPDRSⅡ score, UPDRS Ⅲ score, and getting up time (P〈0.01). Madopar dosage and H-Y stage significantly affected the 10 m × 2 times (P〈0.05 or P〈0.01). Madopar dosage significantly affected the sleep scale score (P〈0.05). There were also significant correlations between age and TMT-left or TMT-right (P〈0.01), and duration of PD and TMT-right (P〈0.05). Conclusions: The six assessed means of clinical evaluation (including UPDRS Ⅱ and UPDRS Ⅲ scores, sleep scale score, getting up time, 10 m × 2 times, and turning time) are sensitive indexes in all PD patients. H-Y stage and Madopar dosage are the major factors influencing means of clinical assessment of PD treatment. 展开更多
关键词 Parkinson's disease integrated chinese and western medicine therapy means of clinicalevaluation
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Guidelines for diagnosis and treatment of hepatic fibrosis with integrated traditional Chinese and Western medicine(2019 edition) 被引量:11
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作者 Lie-ming Xu Ping Liu 《Journal of Integrative Medicine》 SCIE CAS CSCD 2020年第3期203-213,共11页
In 2006, the Hepatology Committee of Chinese Association of Integrative Medicine issued the "Guidelines for the Prevention and Treatment of Liver Fibrosis with Integrated Traditional Chinese and Western Medicine.... In 2006, the Hepatology Committee of Chinese Association of Integrative Medicine issued the "Guidelines for the Prevention and Treatment of Liver Fibrosis with Integrated Traditional Chinese and Western Medicine." In recent years, the fields of Chinese medicine, Western medicine, and integrative medicine have made rapid advances in basic and clinical research into chronic liver disease, and accumulated new evidence for the prevention and treatment of hepatic fibrosis. Therefore, in order to meet clinical needs, liver disease experts of integrated traditional Chinese and Western medicine were united to revise the previous guidelines in order to help physicians make correct and reasonable decisions in the diagnosis and treatment of hepatic fibrosis. 展开更多
关键词 Hepatic FIBROSIS integrated TRADITIONAL chinese and western medicine medicine chinese TRADITIONAL Diagnosis therapy Practice GUIDELINE
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Acetaminophen-Induced Acute Liver Failure Cured by Integrative Therapy of Chinese and Western Medicine—A Case Report
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作者 张新义 张启明 +3 位作者 王义国 侯豫 庄洁 张健雄 《Chinese Journal of Integrative Medicine》 SCIE CAS 2013年第9期712-715,共4页
Introduction Acetaminophen (APP) is one of the most common antipyretic analgesics and is generally considered as a safe drug. However, acute or accumulative overdose of it can cause liver damage, even liver failure... Introduction Acetaminophen (APP) is one of the most common antipyretic analgesics and is generally considered as a safe drug. However, acute or accumulative overdose of it can cause liver damage, even liver failure. Here we reported a case of an 11-year-old patient with acute liver failure (ALF) induced by taking 0.25 g APP orally, who was successfully treated by integrative Chinese and Western medicine. 展开更多
关键词 A Case Report Acetaminophen-Induced Acute Liver Failure Cured by integrative therapy of chinese and western medicine oral PTA TBIL
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Progress of Integrative Chinese and Western Medicine in Treating Polycystic Ovarian Syndrome Caused Infertilit 被引量:4
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作者 宋娟娟 闫妙娥 +1 位作者 吴效科 侯丽辉 《Chinese Journal of Integrative Medicine》 SCIE CAS 2006年第4期312-316,共5页
Polycystic ovarian syndrome (PCOS) is one of the most popular diseases that cause menstrual dysfunction and infertility in women. The present paper is a brief retrospection on the progress in treatment of PCOS cause... Polycystic ovarian syndrome (PCOS) is one of the most popular diseases that cause menstrual dysfunction and infertility in women. The present paper is a brief retrospection on the progress in treatment of PCOS caused infertility with integrative Chinese and Western medicine (ICWM). It can be seen from these materials that using traditional Chinese medicine (TCM) recipes formulated by Shen-replenishing herbs or acupuncture to reinforce Gan-Shen, regulate Chong-Ren Channels in treating PCOS, stable clinical efficacy could be obtained, with less adverse reaction, though the effect initiated somewhat late. Whereas, when Shen-replenishing recipe and acupuncture are combined with hormone or ovulation promoting drugs of Western medicine, the above-mentioned shortcomings would be overcome. So, this combined therapy is frequently used in clinical practice. 展开更多
关键词 polycystic ovarian syndrome integrative chinese and western medicine therapy traditional chinese medicinal treatment drug therapy
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脑肠同调论针刺治疗急性脑梗死血清代谢组学研究 被引量:2
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作者 董琦 田小刚 +4 位作者 黄继升 窦旭辉 王琦 吴佳 陈红梅 《中华中医药学刊》 CAS 北大核心 2024年第6期165-168,共4页
目的 分析脑肠同调论针刺治疗急性脑梗死的血清代谢组学的影响。方法 纳入2018年3月—2022年12月医院收治的急性脑梗死患者126例作为研究对象,随机数字表法分为两组,对照组63例采用常规疗法,观察组63例在此基础上采用脑肠同调论针刺治疗... 目的 分析脑肠同调论针刺治疗急性脑梗死的血清代谢组学的影响。方法 纳入2018年3月—2022年12月医院收治的急性脑梗死患者126例作为研究对象,随机数字表法分为两组,对照组63例采用常规疗法,观察组63例在此基础上采用脑肠同调论针刺治疗,对比两组治疗效果、神经功能,炎症因子水平以及对血清代谢组学的影响。结果 观察组总有效率为96.83%(61/63),远高于对照组的80.96%(57/63),神经功能缺损评分(NIHSS)评分低于对照组(P<0.05);治疗后观察组白介素-17(Interleukin-17,IL-17)、超敏C反应蛋白(hypersensitive C-reactive protein, hs-CRP)、血浆氧化三甲胺(trimethylamine oxide, TMAO)水平均低于对照组(P<0.05);治疗后观察组苯丙氨酸、溶血卵磷脂、焦谷氨酸水平低于对照组(P<0.05)。结论 脑肠同调论针刺治疗急性脑梗死效果明确,可减轻患者炎症反应,调节其肠道菌群代谢产物水平及氨基酸、磷脂代谢障碍等,使紊乱的代谢趋于正常,以达促进神经功能恢复,改善患者预后的目的,有较高应用价值。 展开更多
关键词 急性脑梗死 脑肠同调针刺疗法 中西医结合疗法 神经功能 炎症因子
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溃疡性结肠炎中西医治疗及护理研究进展 被引量:1
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作者 李东青 范东英 蒋小芳 《中西医结合护理》 2024年第2期168-175,共8页
溃疡性结肠炎是由免疫介导的炎症性肠病,临床症状为反复发作的腹泻、腹痛及黏液脓血便。中西医诊疗各有所长,探索行之有效的中西医结合治疗和护理方法对提高溃疡性结肠炎疗效有着积极意义。本研究总结中西医诊疗溃疡性结肠炎的研究现况... 溃疡性结肠炎是由免疫介导的炎症性肠病,临床症状为反复发作的腹泻、腹痛及黏液脓血便。中西医诊疗各有所长,探索行之有效的中西医结合治疗和护理方法对提高溃疡性结肠炎疗效有着积极意义。本研究总结中西医诊疗溃疡性结肠炎的研究现况及临床护理进展,以期为临床进一步提升溃疡性结肠炎的诊疗质量提供一定的理论依据。 展开更多
关键词 溃疡性结肠炎 中西医结合 护理 饮食护理 情志护理 腹泻 疼痛
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异位妊娠中西医结合保守治疗的现状和展望 被引量:1
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作者 纪诚 陈雪 +1 位作者 叶聪 杨依玲 《长春中医药大学学报》 2024年第3期340-344,共5页
异位妊娠作为一种常见的妇科急症,其治疗策略的优化对于提升育龄女性生殖健康具有重要意义。该文综合分析了中西医结合在异位妊娠保守治疗中的应用现状,并探讨了其未来发展趋势。通过对甲氨蝶呤单药治疗和腹腔镜手术等西医传统方法的评... 异位妊娠作为一种常见的妇科急症,其治疗策略的优化对于提升育龄女性生殖健康具有重要意义。该文综合分析了中西医结合在异位妊娠保守治疗中的应用现状,并探讨了其未来发展趋势。通过对甲氨蝶呤单药治疗和腹腔镜手术等西医传统方法的评估,与中医药治疗如中药、针灸和推拿等方法的综合疗效进行对比,揭示了中西医结合治疗在提高治疗效果和降低副作用方面的潜力。展望未来,个体化治疗方案、微创技术的进步和中药新药的开发,预计将为异位妊娠的保守治疗提供更广阔的视野。本综述强调了中西医结合治疗异位妊娠的优势,并为其在临床实践中的深入应用提供了科学依据。 展开更多
关键词 异位妊娠 中西医结合 保守治疗 药物治疗 针灸疗法 手术治疗
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半夏泻心汤加减联合艾司奥美拉唑镁肠溶片治疗非糜烂性胃食管反流病肝胃郁热证疗效及安全性 被引量:1
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作者 陈丽 张江春 +1 位作者 郭洁 万媛 《河北中医》 2024年第9期1455-1459,共5页
目的观察半夏泻心汤加减联合艾司奥美拉唑镁肠溶片治疗非糜烂性胃食管反流病(NERD)肝胃郁热证的疗效及安全性。方法选择NERD肝胃郁热证患者98例,按随机数字表法分为2组,对照组(n=49)予艾司奥美拉唑镁肠溶片,治疗组(n=49)在对照组基础上... 目的观察半夏泻心汤加减联合艾司奥美拉唑镁肠溶片治疗非糜烂性胃食管反流病(NERD)肝胃郁热证的疗效及安全性。方法选择NERD肝胃郁热证患者98例,按随机数字表法分为2组,对照组(n=49)予艾司奥美拉唑镁肠溶片,治疗组(n=49)在对照组基础上辅以半夏泻心汤加减,连续治疗8周。比较2组疗效及治疗前后中医证候总积分、食管动力[下食管括约肌静息压(LESP)、上食管括约肌静息压(UESP)]、胃肠激素[胃动素、胃泌素、胃促生长素(Ghrelin)、血管活性肠肽(VIP)]、汉密尔顿抑郁量表-17(HAMD-17)评分变化,并观察2组治疗期间不良反应发生情况。结果治疗组总有效率为95.92%(47/49),对照组为73.47%(36/49),治疗组临床疗效优于对照组(P<0.05)。2组治疗后中医证候总积分、HAMD-17评分均较本组治疗前降低(P<0.05),且治疗组均低于对照组(P<0.05)。2组治疗后LESP均较本组治疗前升高(P<0.05),UESP均较本组治疗前降低(P<0.05);治疗后治疗组LESP高于对照组(P<0.05),UESP低于对照组(P<0.05)。2组治疗后胃动素、胃泌素、Ghrelin均较本组治疗前升高(P<0.05),VIP均较本组治疗前降低(P<0.05);治疗后治疗组胃动素、胃泌素、Ghrelin高于对照组(P<0.05),VIP低于对照组(P<0.05)。2组治疗期间均未发生不良反应。结论半夏泻心汤加减联合艾司奥美拉唑镁肠溶片治疗NERD肝胃郁热证疗效肯定,能改善食管动力及抑郁状态,调节胃肠激素,且安全性高。 展开更多
关键词 胃食管反流 中西医结合疗法
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身痛逐瘀汤加味联合盐酸普拉克索片治疗痰瘀痹阻型不宁腿综合征的临床观察 被引量:1
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作者 杜青 宁倩 +5 位作者 徐栋 李鑫 顾宝东 王英超 马先军 赵晓慧 《河北中医》 2024年第1期25-28,共4页
目的观察身痛逐瘀汤加味联合盐酸普拉克索片治疗痰瘀痹阻型不宁腿综合征(RLS)患者的临床疗效。方法将50名痰瘀痹阻型RLS患者按照随机数字表法分为2组,对照组25例予盐酸普拉克索片治疗,治疗组25例在对照组基础上联合身痛逐瘀汤加味治疗。... 目的观察身痛逐瘀汤加味联合盐酸普拉克索片治疗痰瘀痹阻型不宁腿综合征(RLS)患者的临床疗效。方法将50名痰瘀痹阻型RLS患者按照随机数字表法分为2组,对照组25例予盐酸普拉克索片治疗,治疗组25例在对照组基础上联合身痛逐瘀汤加味治疗。2组均治疗1周为1个疗程,治疗2个疗程后统计疗效,比较2组治疗前后国际RLS严重程度评分量表(IRLS)评分、匹兹堡睡眠质量指数量表(PSQI)评分及中医症状评分变化情况。结果治疗组总有效率92.00%(23/25),对照组总有效率60.00%(15/25),治疗组总有效率高于对照组(P<0.05)。与本组治疗前比较,2组治疗后IRLS评分、PSQI评分及中医症状评分均降低(P<0.05),且治疗组治疗后IRLS评分、PSQI评分及中医症状评分均低于对照组(P<0.05)。结论身痛逐瘀汤加味联合盐酸普拉克索片治疗痰瘀痹阻型RLS疗效确切,可有效改善患者临床症状及中医症状,改善患者睡眠质量,操作简便,临床疗效显著,安全性良好。 展开更多
关键词 不宁腿综合征 普拉克索 身痛逐瘀汤 痰瘀痹阻 中西医结合疗法
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扶正通淋散治疗脾肾两虚湿热内蕴型复发性尿路感染的临床研究 被引量:1
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作者 刘兴国 聂晨 +3 位作者 付明洁 曹繁华 杜冬琛 冯定华 《河北中医》 2024年第1期51-55,共5页
目的观察扶正通淋散治疗脾肾两虚湿热内蕴型复发性尿路感染的临床疗效。方法将108例复发性尿路感染患者按照随机数字表方法分为3组,中药组36例予扶正通淋散治疗,西药组36例予临床常规西医治疗,联合组36例予扶正通淋散联合临床常规西医... 目的观察扶正通淋散治疗脾肾两虚湿热内蕴型复发性尿路感染的临床疗效。方法将108例复发性尿路感染患者按照随机数字表方法分为3组,中药组36例予扶正通淋散治疗,西药组36例予临床常规西医治疗,联合组36例予扶正通淋散联合临床常规西医治疗。3组均治疗3个月,随访6个月。比较3组治疗前后尿常规[白细胞计数(WBC)、红细胞计数(RBC)]、尿细菌培养结果、血清炎症相关指标[肿瘤坏死因子α(TNF-α)、降钙素原(PCT)、白细胞介素6(IL-6)],治疗前及治疗结束后1个月健康调查简表(SF-36)评分,并统计临床疗效及复发率。结果联合组总有效率91.67%(33/36),中药组总有效率72.22%(26/36),西药组总有效率66.67%(24/36),联合组疗效优于中药组、西药组(P<0.05)。3组治疗后尿常规WBC、RBC均较本组治疗前降低(P<0.05),且联合组治疗后均低于中药组、西药组(P<0.05),中药组均低于西药组(P<0.05)。3组治疗后血清TNF-α、PCT、IL-6水平均较本组治疗前降低(P<0.05),且联合组治疗后均低于中药组、西药组(P<0.05),中药组均低于西药组(P<0.05)。3组治疗后SF-36量表各维度评分均较本组治疗前升高(P<0.05),且联合组均高于中药组、西药组(P<0.05)。联合组尿路感染复发率显著低于中药组、西药组(P<0.05)。结论扶正通淋散治疗脾肾两虚湿热内蕴型复发性尿路感染有较好疗效,可以显著改善患者炎症水平和生活质量,降低复发率。 展开更多
关键词 复发性尿路感染 中西医结合疗法
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耳穴疗法联合普瑞巴林胶囊治疗气滞血瘀型带状疱疹后遗神经痛临床观察 被引量:2
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作者 于涓 《中国中医药现代远程教育》 2024年第12期136-138,共3页
目的分析耳穴疗法联合普瑞巴林胶囊治疗气滞血瘀型带状疱疹后遗神经痛(PHN)的临床效果。方法经随机方式把80例带状疱疹(HZ)住院患者归入对照组、治疗组,分别实施常规治护+普瑞巴林胶囊口服止痛疗法、常规治护+中医耳穴压豆+普瑞巴林胶... 目的分析耳穴疗法联合普瑞巴林胶囊治疗气滞血瘀型带状疱疹后遗神经痛(PHN)的临床效果。方法经随机方式把80例带状疱疹(HZ)住院患者归入对照组、治疗组,分别实施常规治护+普瑞巴林胶囊口服止痛疗法、常规治护+中医耳穴压豆+普瑞巴林胶囊口服止痛疗法,对比两组神经痛改善状况。结果在疼痛缓解方面,相较对照组,治疗组具有显著优势(P<0.05)。治疗组总有效率为90.00%(36/40),高于对照组的77.50%(31/40);治疗组的复发率为10.00%(4/40),低于对照组的22.50%(9/40)(P<0.05)。结论耳穴压豆+普瑞巴林胶囊疗法对于气滞血瘀型PHN的缓解有着积极作用,同时止痛效果相较单用普瑞巴林胶囊更具优势。 展开更多
关键词 蛇串疮 带状疱疹后遗神经痛 气滞血瘀证 耳穴压豆疗法 普瑞巴林 中西医结合疗法
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藤花脉络复新方内服与黄连膏外敷联合西医治疗下肢血栓性浅静脉炎继发静脉溃疡的效果观察
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作者 张凯 武云哲 +1 位作者 王翠敏 李晓东 《辽宁中医药大学学报》 CAS 2024年第7期151-154,共4页
目的 观察藤花脉络复新方内服与黄连膏外敷联合西医对下肢血栓性浅静脉炎继发静脉溃疡的治疗效果。方法 前瞻性选取2019年1月—2020年12月接受治疗的115例下肢血栓性浅静脉炎继发静脉溃疡患者为研究对象,并根据随机数字表法将其分为对照... 目的 观察藤花脉络复新方内服与黄连膏外敷联合西医对下肢血栓性浅静脉炎继发静脉溃疡的治疗效果。方法 前瞻性选取2019年1月—2020年12月接受治疗的115例下肢血栓性浅静脉炎继发静脉溃疡患者为研究对象,并根据随机数字表法将其分为对照组(50例)和观察组(65例),两组均给予常规西药治疗,观察组在此基础上给予藤花脉络复新方内服与黄连膏外敷。比较两组的治疗效果、溃疡面积和疼痛评分、炎症因子水平和生活质量的差异。结果 观察组患者的治疗有效率为100.00%,明显高于对照组的88.00%,差异有统计学意义(χ^(2)值=5.982,P=0.014);两组治疗前疼痛评分和溃疡面积无差别,治疗2周后,观察组患者的疼痛评分低于对照组,溃疡面积较对照组小,差异有统计学意义(P<0.05);两组治疗前炎症因子水平无差别,治疗2周后,观察组的CRP、IL-6和TNF-α水平低于对照组,差异有统计学意义(P<0.01);两组治疗前生活质量无差别,治疗2周后,两组生活质量均较治疗前改善,且观察组优于对照组,差异有统计学意义(P<0.05)。结论 藤花脉络复新方内服与黄连膏外敷联合西医对下肢血栓性浅静脉炎继发静脉溃疡有良好的治疗效果,可改善炎症因子水平和生活质量,有良好的应用价值。 展开更多
关键词 血栓性静脉炎 溃疡 中西医结合 炎症
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清咳平喘颗粒对COPD急性加重期的临床疗效
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作者 李冬生 秦艺榕 +3 位作者 乔曼 迟航 崔青敏 李晓秋 《天津医药》 CAS 2024年第8期854-857,共4页
目的探讨清咳平喘颗粒对慢性阻塞性肺疾病急性加重期(AECOPD)患者临床疗效的影响。方法选取80例呼吸科住院治疗的AECOPD患者,其中常规组和联合组各40例,分别于治疗前、治疗第2周末、治疗1个月后观察2组患者自我评估测试(CAT)评分、疗效... 目的探讨清咳平喘颗粒对慢性阻塞性肺疾病急性加重期(AECOPD)患者临床疗效的影响。方法选取80例呼吸科住院治疗的AECOPD患者,其中常规组和联合组各40例,分别于治疗前、治疗第2周末、治疗1个月后观察2组患者自我评估测试(CAT)评分、疗效指数、白细胞介素(IL)-6水平、C-反应蛋白(CRP)水平、第1秒用力呼气容积(FEV1)/用力肺活量(FVC)、FEV1占预计值百分比(FEV1%pred)的差异。结果联合组总有效率高于常规组(92.5%vs.75.0%,P<0.05)。治疗第2周末,2组FEV1%pred、FEV1/FVC、IL-6水平、CRP水平与治疗前比较均有所改善,且联合组改善程度优于常规组(P<0.05),2组患者呼吸衰竭比例均较治疗前明显好转;随访1个月,联合组CAT评分回弹率低于常规组(P<0.05);2组不良反应发生率差异无统计学意义(12.5%vs.2.5%,P>0.05)。结论清咳平喘颗粒能有效改善AECOPD患者的临床症状及肺功能,提高生活质量。 展开更多
关键词 肺疾病 慢性阻塞性 痰浊阻肺 中西医结合疗法 清咳平喘颗粒
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复方丹参滴丸联合雷米普利片对糖尿病肾病患者肾功能、P选择素水平及糖脂代谢的影响
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作者 黄秀丽 吴艳 +2 位作者 付彩雯 喻荷淋 周艳君 《河北中医》 2024年第5期713-716,721,共5页
目的观察复方丹参滴丸联合雷米普利片对糖尿病肾病(DN)患者肾功能、P选择素水平及糖脂代谢的影响。方法将88例DN患者按照随机数字表法分为2组,对照组44例予雷米普利片治疗,治疗组44例在对照组治疗基础上予复方丹参滴丸治疗。2组均治疗4... 目的观察复方丹参滴丸联合雷米普利片对糖尿病肾病(DN)患者肾功能、P选择素水平及糖脂代谢的影响。方法将88例DN患者按照随机数字表法分为2组,对照组44例予雷米普利片治疗,治疗组44例在对照组治疗基础上予复方丹参滴丸治疗。2组均治疗4周。比较2组治疗前后中医证候评分、肾功能[血尿素氮(BUN)、血肌酐(SCr)及尿蛋白排泄率]、糖脂代谢[餐后2 h血糖(2 hPG)、空腹血糖(FPG)、甘油三酯(TG)、总胆固醇(TC)]、炎症因子[超敏C反应蛋白(hs-CRP)、P选择素、肿瘤坏死因子α(TNF-α)]水平及不良反应发生率。结果2组治疗后中医证候各项评分均较本组治疗前降低(P<0.05),且治疗组治疗后均低于对照组(P<0.05)。2组治疗后BUN、SCr、尿蛋白排泄率均较本组治疗前降低(P<0.05),且治疗组治疗后均低于对照组(P<0.05)。2组治疗后FPG、2 hPG、TG、TC水平均较本组治疗前降低(P<0.05),且治疗组治疗后均低于对照组(P<0.05)。2组治疗后血清hs-CRP、P选择素、TNF-α水平均较本组治疗前降低(P<0.05),且治疗组治疗后均低于对照组(P<0.05)。治疗组不良反应发生率11.36%(5/44),对照组不良反应发生率4.55%(2/44),2组比较差异无统计学意义(P>0.05)。结论复方丹参滴丸联合雷米普利片治疗DN可有效提高肾功能,改善糖脂代谢,减轻炎症反应,降低P选择素水平,安全有效。 展开更多
关键词 糖尿病肾病 中西医结合疗法
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二天养胎汤联合低分子量肝素治疗复发性自然流产血栓前状态的临床研究
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作者 向丽娟 戴海青 +2 位作者 戴小萍 曾根 周意 《河北中医》 2024年第10期1617-1622,共6页
目的观察二天养胎汤联合低分子量肝素对复发性自然流产(RSA)血栓前状态的治疗效果。方法选取2021年10月至2022年11月海南省中医院妇产科门诊就诊及住院的RSA血栓前状态早期妊娠,中医辨证为肾虚血瘀患者80例,采用随机数字法将符合纳入标... 目的观察二天养胎汤联合低分子量肝素对复发性自然流产(RSA)血栓前状态的治疗效果。方法选取2021年10月至2022年11月海南省中医院妇产科门诊就诊及住院的RSA血栓前状态早期妊娠,中医辨证为肾虚血瘀患者80例,采用随机数字法将符合纳入标准患者分为2组,二天养胎汤联合低分子量肝素治疗组(联合治疗组)和低分子量肝素治疗组(肝素治疗组)。其中肝素治疗组入院后给予患者脐周皮下注射低分子量肝素4100 U,每日1次,用药至孕12周。联合治疗组同期予中药二天养胎汤口服。观察各组患者用药前后的治疗效果、中医证候评分改善情况、凝血指标及生长因子和Rho相关卷曲螺旋形成蛋白激酶/LIM激酶1/丝切蛋白(ROCK/LIMK1/Cofilin)通路相关基因表达情况。结果联合治疗组与肝素治疗组相比,其总有效率及活产率均较高,差异有统计学意义(P<0.05)。2组患者治疗前,中医证候积分无明显差别(P>0.05);2组患者治疗后与治疗前相比中医证候积分均有改善(P<0.05),但联合治疗组与肝素治疗组相比,其中医证候评分较低,差异有统计学意义(P<0.05)。2组患者治疗前,各凝血指标无明显差别(P>0.05);联合治疗组治疗后与治疗前相比各凝血指标均有改善(P<0.05);肝素治疗组治疗后与治疗前相比,其纤维蛋白原(FIB)、D-二聚体(D-D)、抗凝血酶Ⅲ(ATⅢ)、活化部分凝血活酶时间(APTT)、凝血酶原时间(PT)有改善(P<0.05)。联合治疗组与肝素治疗组相比,其凝血功能指标均有不同程度的改善,差异有统计学意义(P<0.05)。2组患者治疗前,孕激素及血清相关因子无明显差别(P>0.05);联合治疗组治疗后与治疗前相比各凝血指标均有改善(P<0.05);肝素治疗组治疗后与治疗前相比,其孕酮(P)、人绒毛膜促性腺激素(β-HCG)、一氧化氮(NO)、透明质酸(HA)、血管内皮生长因子A(VEGFA)、胰岛素样生长因子-1(IGF-1)、转化生长因子β1(TGF-β1)有改善(P<0.05)。联合治疗组与肝素治疗组相比,孕激素及血清相关因子均有不同程度的改善,差异有统计学意义(P<0.05)。联合治疗组与肝素治疗组相比,其ROCK、LIMK1表达有所升高(P<0.05),其中LIMK1升高最明显。结论二天养胎汤能够有效改善RSA血栓前状态患者的活产率,维持凝血功能的正常;除此作用外,还可以通过改善血清生长因子VEGFA、IGF-1、TGF-β1以及血管功能保护因子NO、HA调节血栓前状态RSA患者的血管生长及维持血管正常功能,而这些作用可能与二天养胎汤能够通过促进Cofilin的磷酸化激酶ROCK、LIMK1的表达相关。 展开更多
关键词 复发性流产 低分子量肝素 中西医结合疗法
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