HPLC-MS/MS methods were developed to determine 19 kinds of free amino acids in human serum. API 4000 and Quattro Ultima HPLC-MS/MS systems were used in this study. The established method proved to be fast and specific...HPLC-MS/MS methods were developed to determine 19 kinds of free amino acids in human serum. API 4000 and Quattro Ultima HPLC-MS/MS systems were used in this study. The established method proved to be fast and specific.It can be applied to determine 19 kinds of amino acids simultaneously and also can be used in the disease screening studies associated with amino acids disorders.展开更多
文摘HPLC-MS/MS methods were developed to determine 19 kinds of free amino acids in human serum. API 4000 and Quattro Ultima HPLC-MS/MS systems were used in this study. The established method proved to be fast and specific.It can be applied to determine 19 kinds of amino acids simultaneously and also can be used in the disease screening studies associated with amino acids disorders.