Effect of internet multiple linkage mode-based extended care combined with in-hospital comfort care on colorectal cancer patients undergoing colostomy

BACKGROUND Patients with colorectal cancer may need postoperative nursing to improve prognosis,and conventional nursing is not effective.Clinical research is needed to explore nursing methods that can more effectively improve postoperative conditions on colorectal cancer patients undergoing colostomy.AIM To explore the effect of internet multiple linkage mode-based extended care combined with in-hospital comfort care on colorectal cancer patients undergoing colostomy.METHODS Data from 187 patients with colostomy treated in our hospital from May 2019 to March 2022 were collected and divided into three groups,A(n=62),B(n=62)and C(n=63),according to different intervention methods.Group A received internet multiple linkage mode-based extended care combined with in-hospital comfort care.Group B received internet multiple linkage mode-based extended care.Group C received usual care intervention.Complications were compared among the three groups.The stoma self-efficacy scale,Hamilton Anxiety Scale,RESULTS The complication rate of group A,B and C(16.13%,20.97%and 60.32%,respectively)was significantly different(all P<0.05).The incidence of complications in groups A and B was lower than that in group C,and there was no significant difference between groups A and B(P>0.05).After intervention,the scores of ostomy care,social contact,diet choice,confidence in maintaining vitality,confidence in self-care of ostomy,confidence in sexual life,confidence in sexual satisfaction and confidence in physical labor in the three groups were all higher than before intervention,and the scores of groups A and B were higher than those of group C,with statistical significance(P<0.05).The Hamilton Anxiety Scale and Hamilton Depression Scale scores of the three groups after intervention were lower than those before intervention.The scores of groups A and B were lower than those of group C,and the score of group A was lower than that of group B,all with statistical significance(all P<0.05).There was a statist-ically significant difference in cancer-induced fatigue among the three groups(P<0.05).After intervention,the scores of physical health,psychological health,social health and mental health of the three groups were lower than before the intervention.The scores of group A and B were lower than that of group C;and the score of group A was lower than that of group B,all with statistical significance(all P<0.05).CONCLUSION Internet multiple linkage mode-based extended care combined with in-hospital comfort care can effectively improve self-efficacy,bad mood,cancer-related fatigue and life quality of colorectal cancer patients undergoing colostomy.

Psychological preparation practices for children undergoing medical procedures in Japan and Germany

The present study aimed to clarify the current status and awareness of psychological preparation for children undergoing medical procedures in pediatric nursing in Japan as compared with that in Germany. An original questionnaire about the current status and awareness of psychological preparation for children in hospitals was distributed by mail to nurses’ working on Japanese pediatric wards in 2010. The same questionnaire, translated into German, was distributed to nurses working on German pediatric wards via the internet in 2010. A large majority of respondents strongly agreed that children have a right to informed consent. German nurses expressed a longer-term viewpoint on the effects of preparation than Japanese nurses. Japanese nurses recognized a greater need for improvement in their duties than German nurses. The results suggest that we should consider our own country’s nursing practices and need for improvement, but also learn from studies of other countries to address each culture and medical situation appropriately.

Tumor cells undergoing direct lineage conversion to neurons: unnatural but useful?

Dear Editor, In 2011, Son et al. （2011） reported that the forced expression of selected transcription factors is sufficient to convert mouse and human fibroblasts into induced motor neurons （iMNs）. The authors used three factors （Ascll, Brn2, and Mytll） to convert fibroblasts into neuronal-like ceils. After confirming that the cells had neuronal morphology, but with absence of motor neuron markers, eight candidate transcription factors were added, which participate in various stages of motor neuron specification. As expected, a significant number of motor cells emerged with known characteristics of cultured embryonic motor neurons.

Impact of early intensive rehabilitation care in patients undergoing cardiac surgery in a single center:a quasi-experimental study

Objective To evaluate the impact of early intensive rehabilitation care in adults undergoing cardiac surgery.Methods This was a quasi-experimental study using assessor blinding in 252 cardiac surgery patients recruited from Fuwai Hospital.Participants awaiting cardiac surgery were divided into the experiment group and the control group.The control group received routine rehabilitation care postoperatively,including the exercise training,deep breathing exercises,nutrition direction,medication instruction,psychological education,pain management and sleep conditioning.

The psychological trajectory from diagnosis to approaching end of life in patients undergoing hemodialysis in China: A qualitative study

Background: In China,the number of patients diagnosed with end-stage renal disease has increased rapidly in recent years.Patients undergoing dialysis treatment often experience psychosocial challenges,such as death anxiety,which may potentially cause patients to withdraw from treatment.Nephrology nurses and other practitioners who provide direct care to patients undergoing hemodialysis must understand how these challenges are perceived by patients and affect their daily lives.Aim: This article investigated the psychological trajectory and life experiences of hemodialysis patients to provide complementary guidance for nurses and healthcare practitioners.Method: This study utilized a qualitative descriptive phenomenological design.Data were collected by conducting semistructured interviews and analyzed by content analysis.Data were collected through indepth interviews from May to December 2014.The questions were designed to reveal the life experiences and perspectives of hemodialysis patients.Participants were selected by convenience sampling approach and recruited from outpatients receiving treatment in a blood-purification center in Jiangsu Province,China.Results: Twenty-three participants were recruited.Three stages were extracted from the interview data:(1) afraid stage,(2) adapted stage,and (3) depression stage.Accordingly,three corresponding stages of physiological status were identified: (1) induced stage,(2) stable stage,and (3) severe complications or approaching-end-of-life stage.Conclusions: Patients undergoing dialysis exhibited differing psychological statuses at different physical stages.Thus,nurses must assess the psychophysiological symptoms of patients and design individual care plans for each stage.Future studies should focus on developing stage-specific nursing-care protocols.

Safety and efficacy of trimodality therapy in patients undergoing extrapleural pneumonectomy

Malignant pleural mesothelioma （MPM） is a rare but rapidly deadly disease （1）. Macroscopic complete resection （MCR） is the goal of surgery （2）. MCR seems to have the most significant impact on survival in patients undergoing multimodality treatment for MPM. The role of surgical resection in the management of MPM remains controversial. The selection criterion to perform either extrapleural pneumonectomy （EPP） or extended/radical pleurectomy/ decortication （PD） rely not only on the cardio-pulmonary status of the patient, tumor stage and intraoperative findings but is strongly dependent also on surgeons＇ decision and philosophy. This is reflected by a recent survey of opinions and beliefs among 802 thoracic surgeons, in which EPP was believed to be more effective than PD （3）. Nonetheless, either surgery might achieve MCR.

Effect of lavender aromatherapy on pruritus, anxiety, and sleep quality of patients undergoing hemodialysis: a randomized controlled trial

Background:Patie nts un dergo ing hemodialysis experie nces some symptoms.Pruritus,an xiety,and sleep quality are three of the most com mon symptoms.Eve n though some pharmacological treatme nts use to cope with these symptoms,they are still experie need by the patie nts at a high level.Aim:This study aimed to determine the effect of lavender oil aromatherapy on pruritus,anxiety,and sleep quality of patients undergoing hemodialysis.Method:This randomized con trolled study was carried out betwee n December 2019 and March 2020.Eighty of 895 eligible patients were included in the study.Aromatherapy inhalation and massage together applied to the patients for six weeks.5D-Itch Scale,State Anxiety Inventory(SAI),and Richard Campbell Sleep Questio nn aire(RCSQ)were used for data collecti on.IBM SPSS 25.0 were used for statistical an alysis.Mann-Whit ney U,Wilcox on sig ned-ra nks test,and repeated measures-ANOVA tests were used to compare the difference between the groups and simple regression analysis to investigate the relationship between the dependent and independent variables.Results:Most of the patients were male(57.5%)and aged between 41 and 55 years(52.5%).There was significant difference in the mean scores of SAI(Pretest:44.02±5.33,Post-test:35.40±4.52,P=0.003),5D-Itch scale(Pretest:9.80±2.04,Post-test:7.00±2.31,P=0.001),and RCSQ(Pretest:17.11±40.30,Post-test:58.55±33.74,P=0.002)with in time in the in terve ntio n group.There was a statistically significant differenee between the groups regarding the mean scores of SAI(Intervention:35.40±4.52,Control:46.84±4.62,P=0.003),5D-Itch scale(Intervention:7.00±2.31,Control:8.96±2.05,P=0.004),and RCSQ(Intervention:58.55±33.74,Control:19.93±28.36,P=0.001)after the intervention.Conclusion:After six-weeks intervention,lavender aromatherapy was found an effective way to reduce pruritus,anxiety and to improve the sleep quality of patients undergoing hemodialysis.

Predictive risk factors for prolonged stay in intensive care unit in patients undergoing coronary artery bypass grafting surgery

Objective To describe the preoperative factors of prolonged intensive care unit length of stay after coronary artery bypass grafting. Methods From 1997 to 2009, 1318 patients underwent isolated CABG in our hospital. Retrospective analysis was performed on these cases. Univariate and multivariate analyses

Chang'e 5 Undergoing Thermal Test

Chang’e 5 probe has entered its critical phase of AIT.Units,except the lander,are undergoing thermal test.The flight model of Chang’e 5 is composed of an orbiter,a return capsule,a lander and an ascent unit.The thermal tests on the ascent unit,the lander-as-

Predictive risk factors associated with prolonged stay in the intensive care unit for patients undergoing coronary artery bypass grafting surgery

Objective The rate of post-operative complications has been increased with the changes in patients’age,prolonged duration,more severe and diffused lesions,and more patients with complications in recent years. We try to identify the risk factors associated with prolonged stay in the intensive care unit (ICU) after coronary artery bypass graft surgery (CABG) . Methods 1623 patients who received CABG surgery in Beijing Anzhen Hospital

The clinical study of preoperative external lumbar drainage in patients with aneurysmal subarachnoid hemorrhage in Hunt and Hess grades Ⅰ～Ⅲ undergoing early surgery

Objective To explore the therapeutic effect of preoperative external lumbar drainage in Hunt and Hess grade Ⅰ～Ⅲ patients with subarachnoid hemorrhage (SAH) undergoing early surgery for intracranial aneurysms. Methods 101 cases of gradeⅠ～Ⅲ patients according to the classification of Hunt and Hess

Bleeding risk comparing targeted low-dose heparin with bivalirudin in patients undergoing percutaneous coronary intervention results from a propensity score-matched analysis of the evaluation of drug-eluting stents and ischemic events (EVENT) registry

Background Prior randomized trials have shown reduced bleeding with bivalirudin compared with unfractionated heparin （UFH） in patients undergoing percutaneous coronary intervention （PCI）. However, it is not known if this benefit is also present when UFH doses are more tightly controlled （as measured by activated clotting time, ACT）.

Effects of patency of infarct-related coronary artery on acute outcome in acute myocardial infarction patients undergoing urokinase therapy

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THE ROLE OF ETOPOSIDE (VP-16) IN PREPARATORY REGIMENS FOR PATIENTS WITH LEUKEMIA UNDERGOING ALLOGENEIC BONE MARROW TRANSPLANTATION

In 1983,we began a series of five clinical trials with the goal of reducing the relapse rate following

Bivalirudin versus heparin with or without glycoprotein Ⅱb/Ⅲa inhibitors in?patients with STEMI undergoing primary percutaneous coronary intervention:Pooled patient-level analysis from the

In the HORIZONS-AMI （Harmonizing Outcomes with RevasculariZatiON and Stents in Acute Myocardial Infarction） trial, 3,602 patients undergoing primary percutaneous coronary intervention （PCI） for ST-segment elevation myocardial infarction （STEMI） treated with bivalirudin had lower bleeding and mortality rates, but higher acute stent thrombosis rates compared with heparin ＋ a glycoprotein Ⅱ b/Ⅲ a inhibitor （GPI）. Subse- quent changes in primary PCI, including the use of potent P2Y_12 inhibitors, frequent radial intervention, and pre-hospital medication administration, were incorporated into the EUROMAX （European Ambulance Acute Coronary Syndrome Angiography） trial, which assigned 2,218 patients to bivalirudin versus heparin ±GPI before primary PCI.

Door-to-balloon time and mortality among patients undergoing primary PCI

Background Current guidelines for the treatment of ST-segment elevation myocardial infarction recommend a door-to-bal- loon time of 90 minutes or less for patients undergoing primary percutaneous coronary intervention （PCI）. Door-to-balloon time has become a performance measure and is the focus of regional and national quality-im- provement initiatives. However, it is not known whether national improvements in door-to-balloon times have been accompanied by a decline in mortality.

Psychological Preparation of Children for Surgery: Awareness Survey Targeting Medical Professionals

The objective of this study was to conduct a nation-wide survey to investigate the state of: 1) the prevalence of psychological preparation of children undergoing surgery;and 2) the awareness of psychological preparation of children by medical professionals (physicians and nurses). We also aimed to identify the issues that need to be addressed next. A total of 178 physicians and 291 nurses working in hospitals where children undergo surgeries participated in this study. Anonymous self-administered questionnaire survey. Physicians and nurses in Japan are aware of the need to provide age-appropriate psychological preparation for children undergoing medical procedures. In current practice, however, our study revealed that surgical orientations are given solely to parents in the absence of the child in approximately 30% of cases. While approximately 60% of respondents felt that the uses of “children’s picture books and booklets” are good methods for delivering explanations to children, only about 20% of respondents were implementing psychological preparation specific to each age group, and half of the respondents were providing verbal explanations alone. Meanwhile, 77% responded that it is “time-consuming” and 48% said, “on the contrary, it may heighten their anxiety”. Also 34.3% said that they “do not know how to explain to a child” and 54.8% of these medical professionals worked in mixed wards. We observed a gap between ideal requirements and current practices. We found that it is essential to: 1) organize training sessions for knowledge acquisition;2) consciously strive to be informed of the actual post-surgery conditions and outcomes of the children;and 3) acquire physical and financial support.

Psychological Preparation of Children for Medical Procedures: An Awareness Survey Targeting Nurses in Japan

Preparation is a means to support the psychological readiness and autonomy of children undergoing medical treatment. In this study, to understand the current practice and application of psychological preparation, using “explaining medical information to a child” as an indicator of respect for children’s rights, we investigated the effect of psychological preparation since 2002. The present study aimed to clarify the current status and awareness of psychological preparation for children undergoing medical procedures in pediatric nursing in Japan. An original questionnaire regarding psychological preparation for children in hospitals was sent by mail to nurses who were working in Japanese pediatric wards in 2010. Based on results from a previous study, nurses’ awareness of psychological preparation for children undergoing medical procedures seems to have improved. However, it was evident that nursing staff working in mixed wards require more specialized knowledge regarding child care, especially in terms of preparation. Furthermore, Japanese nurses recognized a need for improvement concerning their duties. It was also clear that the meaning of preparation remains ambiguous for many nurses. These results suggest that preparation has both psychological and ethical meanings.

Principled Pragmatism:Understanding the EU Position on Economic Relations with China

The EU-China relations have been experiencing noticeable changes in recent years, with the EU turning realist and putting more emphasis on interests in its interactions with China. This "principled pragmatism," reflected in the EU's position on China's Belt and Road Initiative, heralds the crossroads of bilateral relations.

Application of Multi-team Blood Glucose Management Model in Perioperative Period of General Surgery Patients

Objective:In order to explore the application effect of blood glucose management mode of multiteam cooperation in perioperative period of general surgery patients.Methods:The perioperative blood glucose control of 94 patients undergoing surgical treatment in general surgery from January 2016 to March 2019 was reviewed by Non-synchronous.According to the perioperative blood glucose management model of multi-team cooperation,the patients were divided into intervention group and control group.From January 2016 to January 2018,64 patients who did not implemented the multi-team blood glucose management model were the control group and from February 2018 to March 2019,30 patients who implemented the multi-team blood glucose management model were the intervention group,compared with two group about the differences in perioperative blood glucose.Results:It is no statistically significant about two group in highest and lowest blood sugar levels under fasting stats;during the fluid diet the blood sugar level of the intervention group was lower than control group(P<0.05),and when the patients was in the semifluid or food-feeding period,the highest and lowest blood sugar level is that the intervention group was lower than control group(P<0.05).The time of the blood sugar reaching the standard,the coincidence of complications rate and average hospitalization days in the intervention group were particularly lower than control group(P<0.05).Conclusion:If we adopt multiteam blood glucose management model can better control the perioperative blood glucose of patients undergoing general sugar.