Zinc-air batteries(ZABs)are promising energy storage systems because of high theoretical energy density,safety,low cost,and abundance of zinc.However,the slow multi-step reaction of oxygen and heavy reliance on noble-...Zinc-air batteries(ZABs)are promising energy storage systems because of high theoretical energy density,safety,low cost,and abundance of zinc.However,the slow multi-step reaction of oxygen and heavy reliance on noble-metal catalysts hinder the practical applications of ZABs.Therefore,feasible and advanced non-noble-metal elec-trocatalysts for air cathodes need to be identified to promote the oxygen catalytic reaction.In this review,we initially introduced the advancement of ZABs in the past two decades and provided an overview of key developments in this field.Then,we discussed the work-ing mechanism and the design of bifunctional electrocatalysts from the perspective of morphology design,crystal structure tuning,interface strategy,and atomic engineering.We also included theoretical studies,machine learning,and advanced characterization technologies to provide a comprehensive understanding of the structure-performance relationship of electrocatalysts and the reaction pathways of the oxygen redox reactions.Finally,we discussed the challenges and prospects related to designing advanced non-noble-metal bifunctional electrocatalysts for ZABs.展开更多
By analyzing the sustainable development process of strengthening marine environmental protection and global reporting and assessment of marine environmental conditions since the Human Environment Conference, this pap...By analyzing the sustainable development process of strengthening marine environmental protection and global reporting and assessment of marine environmental conditions since the Human Environment Conference, this paper summarizes the scientific connotation of “scientific understanding of the ocean” reflected in the United Nations Global Marine Environmental Assessment Report, proposes the etymological definition and specific coverage, representative global and regional practical experience of scientific understanding of the ocean, and further analyzes and defines the human activities and cognitive evolution process of “scientific understanding of the ocean”. It marks the leap in human cognition in four dimensions: observation and evaluation, intervention and regulation, disciplinary knowledge system, and supporting guarantee system. It condenses the connotation definitions and human practical achievements of each dimension, and puts forward countermeasures and suggestions to strengthen marine environmental protection and sustainable development.展开更多
In this essay,it will be examined how music can be a powerful tool in multicultural education in promoting humanity and cultural sensitivity.As classroom diversity increases,the challenge lies with educators to ensure...In this essay,it will be examined how music can be a powerful tool in multicultural education in promoting humanity and cultural sensitivity.As classroom diversity increases,the challenge lies with educators to ensure that an equal and appropriate learning environment for all students with cultural sensitivity is maintained.To address this problem,therefore,the study explores how music may be effectively incorporated into intercultural education approaches.This paper has evidence that music is a language that has transcended cultures and promotes tolerance,appreciation,and acceptance of diversity through a synthesis of literature and examples.Several implications posit that music can make people feel they belong,enhance the relations of people from diverse cultures,and provide a practical way of learning about other cultures.The potential of music as a tool to engage social justice issues and liberate oppressed groups is also discussed in this research.It exists,but with caution to cultural appropriation and stereotyping of students,thus requiring educators to be sensitive and socially-apperceived on the best practice ways on how to integrate music into classrooms.The end explains how music helps in nurturing a generation of embracing the world,more sensitive and more inclined to the happenings in society to create a society that will be more sensitive and tolerant with the growing society which is diversifying.Therefore,the current article recommends further exploration and development of music-facilitated/inclined pedagogy of ME in hopefully enhancing cultural consciousness/sensitivity and fostering more social integration.展开更多
People learn causal relations since childhood using counterfactual reasoning. Counterfactual reasoning uses counterfactual examples which take the form of “what if this has happened differently”. Counterfactual exam...People learn causal relations since childhood using counterfactual reasoning. Counterfactual reasoning uses counterfactual examples which take the form of “what if this has happened differently”. Counterfactual examples are also the basis of counterfactual explanation in explainable artificial intelligence (XAI). However, a framework that relies solely on optimization algorithms to find and present counterfactual samples cannot help users gain a deeper understanding of the system. Without a way to verify their understanding, the users can even be misled by such explanations. Such limitations can be overcome through an interactive and iterative framework that allows the users to explore their desired “what-if” scenarios. The purpose of our research is to develop such a framework. In this paper, we present our “what-if” XAI framework (WiXAI), which visualizes the artificial intelligence (AI) classification model from the perspective of the user’s sample and guides their “what-if” exploration. We also formulated how to use the WiXAI framework to generate counterfactuals and understand the feature-feature and feature-output relations in-depth for a local sample. These relations help move the users toward causal understanding.展开更多
Teachers’teaching behavior plays a crucial role in students’development,and there are problems in the current teaching behavior of mathematics teachers such as ignoring students’cognitive needs,lack of equal opport...Teachers’teaching behavior plays a crucial role in students’development,and there are problems in the current teaching behavior of mathematics teachers such as ignoring students’cognitive needs,lack of equal opportunities for students’classroom performance as well as lack of formative evaluation of students.In order to solve the phenomenon,this paper analyzes and explains how to promote teaching based on the Teaching for Robust Understanding(TRU)evaluation framework with the goal of focusing on the development of all students,taking the teaching design of The Cosine Theorem as an example,and provides ideas and methods for first-line high school mathematics teachers.展开更多
The author attempts to interpret the theme of A Passsage to India by analyzing the major events and characterization. It is indicated in the thesis that E.M.Forster highlights the failure of aspired understanding ...The author attempts to interpret the theme of A Passsage to India by analyzing the major events and characterization. It is indicated in the thesis that E.M.Forster highlights the failure of aspired understanding between different races, different people and even within a person. In other words, in many cases people have aspirations for understanding, but in reality the real understanding is very difficult to fulfill.展开更多
This is a research report on the interrelationship among understanding, memory and oral expression in listening comprehension training. The research investigated 150 non-English majors through a questionnaire in a hig...This is a research report on the interrelationship among understanding, memory and oral expression in listening comprehension training. The research investigated 150 non-English majors through a questionnaire in a higher vocational college. The result indicates that the interrelationship among understanding, memory and oral expression in listening classes which are determined by the listening materials and teaching method directly influences students' listening proficiency and speaking ability. It is suggested that some strategies to be used to foster students' abilities in these three areas so as to improve their listening ability.展开更多
Distinguished guests,Ladies and gentlemen,Dear friends,It gives me great pleasure to meet all of you in Beijing and join you in the 2013"Understanding and Cooperation"Dialogue.Please allow me to begin by ext...Distinguished guests,Ladies and gentlemen,Dear friends,It gives me great pleasure to meet all of you in Beijing and join you in the 2013"Understanding and Cooperation"Dialogue.Please allow me to begin by extending my warmest congratulations to the opening of this Dialogue,and my展开更多
The article analyzes the translations,performances and the reception of traditional Chinese plays in the English-speaking world from the mid-and-late eighteenth century to the early twentieth century.We found that the...The article analyzes the translations,performances and the reception of traditional Chinese plays in the English-speaking world from the mid-and-late eighteenth century to the early twentieth century.We found that the reception underwent two phases featuring self-centered and multicultural respectively.In the first phase,the English-speaking world acknowledged the moral values of traditional Chinese plays but it did not accept their aesthetic values while in the second phase,aesthetic values became the focus and were received through translations,studies and performances.The two phases differed significantly.The first phase was characterized by the initial contacts and exchanges between the plays and the English culture as well as obvious cultural misunderstandings.During the second phase,moral and aesthetic values were gradually accepted.Text translations,theatrical studies and performances were flourishing while cultural misunderstandings decreased remarkably.The two stages demonstrate the general result of the Chinese culture’s historical process of“going global”.The reception of Chinese culture by other cultures often started with cultural utilization,accompanied by obvious cultural misunderstandings.With the deepening of contacts and exchanges between the two cultures,however,the host culture began to gain a better understanding of the intrinsic values of Chinese culture and therefore cultural misunderstandings decreased.Cultural misunderstandings are an inevitable historical process that the Chinese culture would experience during its“going global”.With continuing and expanded exposures,the intrinsic values of Chinese culture will continue to manifest themselves.展开更多
Osteoarthritis (OA) is the most common degenerative joint disease and a major cause of pain and disability in adult individuals. The etiology of OA includes joint injury, obesity, aging, and heredity. However, the d...Osteoarthritis (OA) is the most common degenerative joint disease and a major cause of pain and disability in adult individuals. The etiology of OA includes joint injury, obesity, aging, and heredity. However, the detailed molecular mechanisms of OA initiation and progression remain poorly understood and, currently, there are no interventions available to restore degraded cartilage or decelerate disease progression. The diathrodial joint is a complicated organ and its function is to bear weight, perform physical activity and exhibit a joint-specific range of motion during movement. During OA development, the entire joint organ is affected, including articular cartilage, subchondral bone, synovial tissue and meniscus. A full understanding of the pathological mechanism of OA development relies on the discovery of the interplaying mechanisms among different OA symptoms, including articular cartilage degradation, osteophyte formation, subchondral sclerosis and synovial hyperplasia, and the signaling pathway(s) controlling these pathological processes.展开更多
After a brief emphasis about the interconnected world, including Cyber-Physical Systems of Systems, the increasing importance of the decision-making by autonomous, quasi-autonomous, and autonomic systems is emphasised...After a brief emphasis about the interconnected world, including Cyber-Physical Systems of Systems, the increasing importance of the decision-making by autonomous, quasi-autonomous, and autonomic systems is emphasised. Promising roles of computational understanding, computational awareness, and computational wisdom for better autonomous decision-making are outlined. The contributions of simulation-based approaches are listed.展开更多
Through detailed analyses of the distribution characteristics of organic-rich shale, appearance features of high-quality shale, microscopic characteristics of shale reservoir rocks, fracability, and the relationship b...Through detailed analyses of the distribution characteristics of organic-rich shale, appearance features of high-quality shale, microscopic characteristics of shale reservoir rocks, fracability, and the relationship between preservation conditions and shale gas enrichment in Upper Ordovician Wufeng Formation-Lower Silurian Longmaxi Formation in Sichuan Basin, theoretical understandings and specific suggestions with respect to the exploration and development of shale gas in China are summarized and proposed respectively. Important geological understandings in the exploration and development of shale gas of the Wufeng Formation–Longmaxi Formation in the Sichuan Basin can be summarized into the following aspects: depositional environment and depositional process control the distribution of organic-rich shale; high quality shale in "sweet spot segments" are commonly characterized by high content of organic carbon, high brittleness, high porosity and gas content; organic pores are important storage space for the enrichment of shale gas; preservation conditions are the key factor for the geological evaluation of shale gas in structurally complex regions; shale gas can be considered as "artificial gas reservoirs" and the fracability assessment is essential for high-production; nanoscale storage space and the mode of occurrence control the special seepage characteristics of shale gas. The following suggestions are proposed for the development of China's shale gas industry:(1) focus more on fundamental research to achieve new breakthrough in the geological theory of shale gas;(2) emphasize exploration practices to have all-round discoveries in multiple strata;(3) study the regularities of development and production to establish new models of shale gas development;(4) think creatively to invent new technologies to tackle key problems;(5) explore the management innovation to create new mechanisms in shale gas development.展开更多
SUMMARY Intracranial calcification may result from disturbances in calcium metabolism. It often remains asymptomatic, but may present with symptoms like seizure and neurological deficits. Correction of the underlying ...SUMMARY Intracranial calcification may result from disturbances in calcium metabolism. It often remains asymptomatic, but may present with symptoms like seizure and neurological deficits. Correction of the underlying metabolic disturbance before damage of neuronal tissues due to intracranial calcification may be useful in preventing irreversible neurological deficits. This window period may be the crucial period that needs a thorough clinical evaluation and urgent intervention. We highlight the case of an adult woman with Fahr's disease presented with generalised tonic-clonic seizure. The management priorities were also discussed along with review of literature.展开更多
Electrochemical carbon dioxide reduction reaction(CO_(2)RR)provides a promising way to convert CO_(2)to chemicals.The multicarbon(C_(2+))products,especially ethylene,are of great interest due to their versatile indust...Electrochemical carbon dioxide reduction reaction(CO_(2)RR)provides a promising way to convert CO_(2)to chemicals.The multicarbon(C_(2+))products,especially ethylene,are of great interest due to their versatile industrial applications.However,selectively reducing CO_(2)to ethylene is still challenging as the additional energy required for the C–C coupling step results in large overpotential and many competing products.Nonetheless,mechanistic understanding of the key steps and preferred reaction pathways/conditions,as well as rational design of novel catalysts for ethylene production have been regarded as promising approaches to achieving the highly efficient and selective CO_(2)RR.In this review,we first illustrate the key steps for CO_(2)RR to ethylene(e.g.,CO_(2)adsorption/activation,formation of~*CO intermediate,C–C coupling step),offering mechanistic understanding of CO_(2)RR conversion to ethylene.Then the alternative reaction pathways and conditions for the formation of ethylene and competitive products(C_1 and other C_(2+)products)are investigated,guiding the further design and development of preferred conditions for ethylene generation.Engineering strategies of Cu-based catalysts for CO_(2)RR-ethylene are further summarized,and the correlations of reaction mechanism/pathways,engineering strategies and selectivity are elaborated.Finally,major challenges and perspectives in the research area of CO_(2)RR are proposed for future development and practical applications.展开更多
Dear editor, We read with pleasure the well-designed study by Butler et al of electrical cardioversion of emergency department patients with atrial fibrillation. We appreciate their analysis of the distinctives of pro...Dear editor, We read with pleasure the well-designed study by Butler et al of electrical cardioversion of emergency department patients with atrial fibrillation. We appreciate their analysis of the distinctives of procedural sedation when employed for this indication. Understanding the dosing adjustments to propofol undertaken by their sedationists will help us more carefully evaluate our own approach to sedating patients undergoing electrical cardioversion of atrial fibrillation.展开更多
System dynamics shows how the structure and policies in a system produce change through time. System dynamics deals with the internal processes that produce good and bad behavior in social, economic, and environmental...System dynamics shows how the structure and policies in a system produce change through time. System dynamics deals with the internal processes that produce good and bad behavior in social, economic, and environmental systems. In a system dynamics study, one builds a computer model that acts out the behavior of the real system being represented. The computer model is then used to展开更多
The dramatic changes in the Arctic climate system during recent decades are one of the most prominent features of global climate change.Two most striking and fundamental characteristics are the amplified near-surface ...The dramatic changes in the Arctic climate system during recent decades are one of the most prominent features of global climate change.Two most striking and fundamental characteristics are the amplified near-surface warming at a rate twice the global average since the mid 20th century(e.g.,Blunden and Arndt,2012;Huang et al.,2017),and the rapid展开更多
Meaning in the learning of a language is communicated in many different forms. All meaning is communicated in some form of context and the only way to understanding them is in context. In the learning of English, unde...Meaning in the learning of a language is communicated in many different forms. All meaning is communicated in some form of context and the only way to understanding them is in context. In the learning of English, understanding the cultural context is the most effective way to learn real meaning and to read, write and speak competently.展开更多
基金the Natural Science Foundation of China(Grant No:22309180)Strategic Priority Research Program of the Chinese Academy of Sciences(Grant No:XDB0600000,XDB0600400)+3 种基金Liaoning Binhai Laboratory,(Grant No:LILBLB-2023-04)Dalian Revitalization Talents Program(Grant No:2022RG01)Youth Science and Technology Foundation of Dalian(Grant No:2023RQ015)the University of Waterloo.
文摘Zinc-air batteries(ZABs)are promising energy storage systems because of high theoretical energy density,safety,low cost,and abundance of zinc.However,the slow multi-step reaction of oxygen and heavy reliance on noble-metal catalysts hinder the practical applications of ZABs.Therefore,feasible and advanced non-noble-metal elec-trocatalysts for air cathodes need to be identified to promote the oxygen catalytic reaction.In this review,we initially introduced the advancement of ZABs in the past two decades and provided an overview of key developments in this field.Then,we discussed the work-ing mechanism and the design of bifunctional electrocatalysts from the perspective of morphology design,crystal structure tuning,interface strategy,and atomic engineering.We also included theoretical studies,machine learning,and advanced characterization technologies to provide a comprehensive understanding of the structure-performance relationship of electrocatalysts and the reaction pathways of the oxygen redox reactions.Finally,we discussed the challenges and prospects related to designing advanced non-noble-metal bifunctional electrocatalysts for ZABs.
文摘By analyzing the sustainable development process of strengthening marine environmental protection and global reporting and assessment of marine environmental conditions since the Human Environment Conference, this paper summarizes the scientific connotation of “scientific understanding of the ocean” reflected in the United Nations Global Marine Environmental Assessment Report, proposes the etymological definition and specific coverage, representative global and regional practical experience of scientific understanding of the ocean, and further analyzes and defines the human activities and cognitive evolution process of “scientific understanding of the ocean”. It marks the leap in human cognition in four dimensions: observation and evaluation, intervention and regulation, disciplinary knowledge system, and supporting guarantee system. It condenses the connotation definitions and human practical achievements of each dimension, and puts forward countermeasures and suggestions to strengthen marine environmental protection and sustainable development.
文摘In this essay,it will be examined how music can be a powerful tool in multicultural education in promoting humanity and cultural sensitivity.As classroom diversity increases,the challenge lies with educators to ensure that an equal and appropriate learning environment for all students with cultural sensitivity is maintained.To address this problem,therefore,the study explores how music may be effectively incorporated into intercultural education approaches.This paper has evidence that music is a language that has transcended cultures and promotes tolerance,appreciation,and acceptance of diversity through a synthesis of literature and examples.Several implications posit that music can make people feel they belong,enhance the relations of people from diverse cultures,and provide a practical way of learning about other cultures.The potential of music as a tool to engage social justice issues and liberate oppressed groups is also discussed in this research.It exists,but with caution to cultural appropriation and stereotyping of students,thus requiring educators to be sensitive and socially-apperceived on the best practice ways on how to integrate music into classrooms.The end explains how music helps in nurturing a generation of embracing the world,more sensitive and more inclined to the happenings in society to create a society that will be more sensitive and tolerant with the growing society which is diversifying.Therefore,the current article recommends further exploration and development of music-facilitated/inclined pedagogy of ME in hopefully enhancing cultural consciousness/sensitivity and fostering more social integration.
文摘People learn causal relations since childhood using counterfactual reasoning. Counterfactual reasoning uses counterfactual examples which take the form of “what if this has happened differently”. Counterfactual examples are also the basis of counterfactual explanation in explainable artificial intelligence (XAI). However, a framework that relies solely on optimization algorithms to find and present counterfactual samples cannot help users gain a deeper understanding of the system. Without a way to verify their understanding, the users can even be misled by such explanations. Such limitations can be overcome through an interactive and iterative framework that allows the users to explore their desired “what-if” scenarios. The purpose of our research is to develop such a framework. In this paper, we present our “what-if” XAI framework (WiXAI), which visualizes the artificial intelligence (AI) classification model from the perspective of the user’s sample and guides their “what-if” exploration. We also formulated how to use the WiXAI framework to generate counterfactuals and understand the feature-feature and feature-output relations in-depth for a local sample. These relations help move the users toward causal understanding.
基金Henan Province 2022 Teacher Education Curriculum Reform Research Project:Research on Improving the Teaching Practice Ability of Mathematics Normal University Students under the OBE Concept(Project number:2022-JSJYZD-009)A Study on the Measurement and Development of Mathematics Core Literacy for Secondary School Students,Doctoral Research Initiation Fee of Henan Normal University(Project number:20230234)Henan Normal University Graduate Quality Course Program,Mathematical Planning I(Project number:YJS2022KC02)。
文摘Teachers’teaching behavior plays a crucial role in students’development,and there are problems in the current teaching behavior of mathematics teachers such as ignoring students’cognitive needs,lack of equal opportunities for students’classroom performance as well as lack of formative evaluation of students.In order to solve the phenomenon,this paper analyzes and explains how to promote teaching based on the Teaching for Robust Understanding(TRU)evaluation framework with the goal of focusing on the development of all students,taking the teaching design of The Cosine Theorem as an example,and provides ideas and methods for first-line high school mathematics teachers.
文摘The author attempts to interpret the theme of A Passsage to India by analyzing the major events and characterization. It is indicated in the thesis that E.M.Forster highlights the failure of aspired understanding between different races, different people and even within a person. In other words, in many cases people have aspirations for understanding, but in reality the real understanding is very difficult to fulfill.
文摘This is a research report on the interrelationship among understanding, memory and oral expression in listening comprehension training. The research investigated 150 non-English majors through a questionnaire in a higher vocational college. The result indicates that the interrelationship among understanding, memory and oral expression in listening classes which are determined by the listening materials and teaching method directly influences students' listening proficiency and speaking ability. It is suggested that some strategies to be used to foster students' abilities in these three areas so as to improve their listening ability.
文摘Distinguished guests,Ladies and gentlemen,Dear friends,It gives me great pleasure to meet all of you in Beijing and join you in the 2013"Understanding and Cooperation"Dialogue.Please allow me to begin by extending my warmest congratulations to the opening of this Dialogue,and my
文摘The article analyzes the translations,performances and the reception of traditional Chinese plays in the English-speaking world from the mid-and-late eighteenth century to the early twentieth century.We found that the reception underwent two phases featuring self-centered and multicultural respectively.In the first phase,the English-speaking world acknowledged the moral values of traditional Chinese plays but it did not accept their aesthetic values while in the second phase,aesthetic values became the focus and were received through translations,studies and performances.The two phases differed significantly.The first phase was characterized by the initial contacts and exchanges between the plays and the English culture as well as obvious cultural misunderstandings.During the second phase,moral and aesthetic values were gradually accepted.Text translations,theatrical studies and performances were flourishing while cultural misunderstandings decreased remarkably.The two stages demonstrate the general result of the Chinese culture’s historical process of“going global”.The reception of Chinese culture by other cultures often started with cultural utilization,accompanied by obvious cultural misunderstandings.With the deepening of contacts and exchanges between the two cultures,however,the host culture began to gain a better understanding of the intrinsic values of Chinese culture and therefore cultural misunderstandings decreased.Cultural misunderstandings are an inevitable historical process that the Chinese culture would experience during its“going global”.With continuing and expanded exposures,the intrinsic values of Chinese culture will continue to manifest themselves.
基金supported by NIH grants AR055915 and AR054465 to DC
文摘Osteoarthritis (OA) is the most common degenerative joint disease and a major cause of pain and disability in adult individuals. The etiology of OA includes joint injury, obesity, aging, and heredity. However, the detailed molecular mechanisms of OA initiation and progression remain poorly understood and, currently, there are no interventions available to restore degraded cartilage or decelerate disease progression. The diathrodial joint is a complicated organ and its function is to bear weight, perform physical activity and exhibit a joint-specific range of motion during movement. During OA development, the entire joint organ is affected, including articular cartilage, subchondral bone, synovial tissue and meniscus. A full understanding of the pathological mechanism of OA development relies on the discovery of the interplaying mechanisms among different OA symptoms, including articular cartilage degradation, osteophyte formation, subchondral sclerosis and synovial hyperplasia, and the signaling pathway(s) controlling these pathological processes.
文摘After a brief emphasis about the interconnected world, including Cyber-Physical Systems of Systems, the increasing importance of the decision-making by autonomous, quasi-autonomous, and autonomic systems is emphasised. Promising roles of computational understanding, computational awareness, and computational wisdom for better autonomous decision-making are outlined. The contributions of simulation-based approaches are listed.
基金Supported by the Chinese Academy of Engineering Consultancy Project(2018-xz-09-01)
文摘Through detailed analyses of the distribution characteristics of organic-rich shale, appearance features of high-quality shale, microscopic characteristics of shale reservoir rocks, fracability, and the relationship between preservation conditions and shale gas enrichment in Upper Ordovician Wufeng Formation-Lower Silurian Longmaxi Formation in Sichuan Basin, theoretical understandings and specific suggestions with respect to the exploration and development of shale gas in China are summarized and proposed respectively. Important geological understandings in the exploration and development of shale gas of the Wufeng Formation–Longmaxi Formation in the Sichuan Basin can be summarized into the following aspects: depositional environment and depositional process control the distribution of organic-rich shale; high quality shale in "sweet spot segments" are commonly characterized by high content of organic carbon, high brittleness, high porosity and gas content; organic pores are important storage space for the enrichment of shale gas; preservation conditions are the key factor for the geological evaluation of shale gas in structurally complex regions; shale gas can be considered as "artificial gas reservoirs" and the fracability assessment is essential for high-production; nanoscale storage space and the mode of occurrence control the special seepage characteristics of shale gas. The following suggestions are proposed for the development of China's shale gas industry:(1) focus more on fundamental research to achieve new breakthrough in the geological theory of shale gas;(2) emphasize exploration practices to have all-round discoveries in multiple strata;(3) study the regularities of development and production to establish new models of shale gas development;(4) think creatively to invent new technologies to tackle key problems;(5) explore the management innovation to create new mechanisms in shale gas development.
文摘SUMMARY Intracranial calcification may result from disturbances in calcium metabolism. It often remains asymptomatic, but may present with symptoms like seizure and neurological deficits. Correction of the underlying metabolic disturbance before damage of neuronal tissues due to intracranial calcification may be useful in preventing irreversible neurological deficits. This window period may be the crucial period that needs a thorough clinical evaluation and urgent intervention. We highlight the case of an adult woman with Fahr's disease presented with generalised tonic-clonic seizure. The management priorities were also discussed along with review of literature.
基金financially supported via Australian Research Council(FT180100705)the support by the National Natural Science Foundation of China(22209103)+3 种基金the support from UTS Chancellor's Research Fellowshipsthe support from Open Project of State Key Laboratory of Advanced Special Steel,the Shanghai Key Laboratory of Advanced Ferrometallurgy,Shanghai University(SKLASS 2021-**)Joint International Laboratory on Environmental and Energy Frontier MaterialsInnovation Research Team of High-Level Local Universities in Shanghai。
文摘Electrochemical carbon dioxide reduction reaction(CO_(2)RR)provides a promising way to convert CO_(2)to chemicals.The multicarbon(C_(2+))products,especially ethylene,are of great interest due to their versatile industrial applications.However,selectively reducing CO_(2)to ethylene is still challenging as the additional energy required for the C–C coupling step results in large overpotential and many competing products.Nonetheless,mechanistic understanding of the key steps and preferred reaction pathways/conditions,as well as rational design of novel catalysts for ethylene production have been regarded as promising approaches to achieving the highly efficient and selective CO_(2)RR.In this review,we first illustrate the key steps for CO_(2)RR to ethylene(e.g.,CO_(2)adsorption/activation,formation of~*CO intermediate,C–C coupling step),offering mechanistic understanding of CO_(2)RR conversion to ethylene.Then the alternative reaction pathways and conditions for the formation of ethylene and competitive products(C_1 and other C_(2+)products)are investigated,guiding the further design and development of preferred conditions for ethylene generation.Engineering strategies of Cu-based catalysts for CO_(2)RR-ethylene are further summarized,and the correlations of reaction mechanism/pathways,engineering strategies and selectivity are elaborated.Finally,major challenges and perspectives in the research area of CO_(2)RR are proposed for future development and practical applications.
文摘Dear editor, We read with pleasure the well-designed study by Butler et al of electrical cardioversion of emergency department patients with atrial fibrillation. We appreciate their analysis of the distinctives of procedural sedation when employed for this indication. Understanding the dosing adjustments to propofol undertaken by their sedationists will help us more carefully evaluate our own approach to sedating patients undergoing electrical cardioversion of atrial fibrillation.
文摘System dynamics shows how the structure and policies in a system produce change through time. System dynamics deals with the internal processes that produce good and bad behavior in social, economic, and environmental systems. In a system dynamics study, one builds a computer model that acts out the behavior of the real system being represented. The computer model is then used to
文摘The dramatic changes in the Arctic climate system during recent decades are one of the most prominent features of global climate change.Two most striking and fundamental characteristics are the amplified near-surface warming at a rate twice the global average since the mid 20th century(e.g.,Blunden and Arndt,2012;Huang et al.,2017),and the rapid
文摘Meaning in the learning of a language is communicated in many different forms. All meaning is communicated in some form of context and the only way to understanding them is in context. In the learning of English, understanding the cultural context is the most effective way to learn real meaning and to read, write and speak competently.