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Changing landscape in living kidney donation in Greece 被引量:1
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作者 Nikolaos Karydis Ioannis Maroulis 《World Journal of Transplantation》 2023年第2期28-35,共8页
Patients with end-stage renal disease in Greece are facing long waiting times to receive a kidney transplant from a deceased donor.Living kidney donation offers a valuable alternative that provides optimal outcomes an... Patients with end-stage renal disease in Greece are facing long waiting times to receive a kidney transplant from a deceased donor.Living kidney donation offers a valuable alternative that provides optimal outcomes and significantly expands the donor pool but still remains relatively underutilised.Developments around the world in the field of kidney transplantation mandate a change in current practice to include additional options for living donation through paired exchange,antibody-incompatible transplantation and other strategies,following careful consideration of the cultural and ethical factors involved in these complex clinical decisions.An increase in living donation rates may be achieved in several ways,including targeted campaigning to overcome potential barriers.Educating clinicians on transplantation will prove as equally important as informing patients and prospective donors but requires training and resources.Adoption of established practices and implementation of new strategies must be tailored to the needs of the Greek donor and recipient population.Local beliefs about donation,perception of associated risk and other social characteristics must be considered in the design of future strategies.Facilitating living donation in a safe environment with appropriate donor and recipient education will form the solid foundation of a new era of kidney transplantation in Greece. 展开更多
关键词 Living kidney donation paired exchange Incompatible transplantation unrelated donors Greece
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The impact of HLA haplotype and alleles mismatches of donor-recipient pairs on outcome of haplo-identical hematopoietic stem cell transplantation with a third part cord blood unit
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作者 朱文娟 《China Medical Abstracts(Internal Medicine)》 2016年第3期176-177,共2页
Objective To analyze allele mismatches of HLA-A,-B,-C,-DRB1,-DQB1 and haplotype mismatch of donor-recipient pairs on the outcome of haploidentical transplantation combined with a third part cord blood unit.Methods 230... Objective To analyze allele mismatches of HLA-A,-B,-C,-DRB1,-DQB1 and haplotype mismatch of donor-recipient pairs on the outcome of haploidentical transplantation combined with a third part cord blood unit.Methods 230 pairs of donor-recipient were performed HLA-A,B,C,DRB1,DQB1 typing using 展开更多
关键词 HLA The impact of HLA haplotype and alleles mismatches of donor-recipient pairs on outcome of haplo-identical hematopoietic stem cell transplantation with a third part cord blood unit
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编码非相关词对是否具有半球对称性?一项近红外光学成像的研究(英文) 被引量:3
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作者 杨炯炯 曾少群 +5 位作者 骆清铭 管林初 匡培梓 龚辉 Lichty Wemara Chance Britton 《航天医学与医学工程》 CAS CSCD 北大核心 2005年第5期318-323,共6页
目的本研究采用近红外光学成像技术(fNIRS),探讨双侧前额叶在非相关词对的语义编码过程中的作用。方法48名被试者分别在深、浅加工2种实验条件下对非相关词对进行编码,光学成像器即时记录在前额叶皮层,波长为760nm和850nm的漫射光强变化... 目的本研究采用近红外光学成像技术(fNIRS),探讨双侧前额叶在非相关词对的语义编码过程中的作用。方法48名被试者分别在深、浅加工2种实验条件下对非相关词对进行编码,光学成像器即时记录在前额叶皮层,波长为760nm和850nm的漫射光强变化,以此推测相应脑组织的血容量变化。结果与浅加工相比,在深加工条件下,双侧前额叶中与背外侧前额叶相对应区域的血容量变化都较为明显,尤其是左侧前额叶。本研究结果并不完全支持HERA模型,但与其它相关的脑成像研究结果相似。结论材料的特异性是影响记忆编码中半球一侧化的重要因素,当需要对刺激间的联系进行加工时,右侧前额叶也会参与记忆的编码过程。本研究还提示fNIRS技术可用于记忆等脑高级认知功能的研究。 展开更多
关键词 功能近红外光学技术 前额叶 非相关词对 记忆的编码与提取半球不对称性模型 记忆
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一种基于露点的阀门泄漏非相关故障分析 被引量:1
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作者 傅乐平 于文凯 杨洋 《润滑与密封》 CAS CSCD 北大核心 2016年第5期126-129,共4页
某菌状止口密封副在采用箱外测试法进行测试时,发现该密封副在低温下出现漏率突变。采用故障树分析法对该密封副进行相关故障和非相关故障分析,从露点的角度确定阀门泄漏是由于低温环境试验中由于试验方法不正确导致的阀门本身产生温差... 某菌状止口密封副在采用箱外测试法进行测试时,发现该密封副在低温下出现漏率突变。采用故障树分析法对该密封副进行相关故障和非相关故障分析,从露点的角度确定阀门泄漏是由于低温环境试验中由于试验方法不正确导致的阀门本身产生温差而引起的。提出改进试验方法方案,消除该阀门隐性的非相关故障成因,为杜绝同类阀门产品的类似故障提供参考。 展开更多
关键词 低温环境试验 止口密封副 密封比压 非相关故障 露点
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HLA-A、-B、-C、-DRBl和-DQB1等位基因全相合的无关供一受者对的HLA-DPA1和-DPB1基因匹配性研究
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作者 甄建新 邹红岩 +4 位作者 金士正 高素青 王大明 何柳媚 邓志辉 《中华医学遗传学杂志》 CAS CSCD 北大核心 2013年第6期697-700,共4页
目的研究HLA-A、-B、-C、-DRB1和-DQB1等位基因全相合的无关供-受者对HLA-DPA1和-DPB1基因的匹配性。方法对76对HLA-A、-B、-C、-DRB1和-DQB1等位基因10/10相合的无关供-受者样本进行HLA~DPA1和-DPB1基因测序分型,从等位基因水平统... 目的研究HLA-A、-B、-C、-DRB1和-DQB1等位基因全相合的无关供-受者对HLA-DPA1和-DPB1基因的匹配性。方法对76对HLA-A、-B、-C、-DRB1和-DQB1等位基因10/10相合的无关供-受者样本进行HLA~DPA1和-DPB1基因测序分型,从等位基因水平统计和分析HLA-DPA1和-DP通信作者:邓志辉,Emai1:zhihui-deng@sina.cn基因匹配的比例和特点。结果单个HI。A-DPA1、-DPB1基因高分辨水平完全相合的比例分别为17.1%、9.2%,完全相合的比例均较低。HI,A-DPA1等位基因半相合的比例占绝大多数(73.7%),完全不合的比例为9.2%;具有高度多态性的HLA-DPB1基因半相合的比例为57.9%,而完全不合的比例为32.9%。统计HLA-DPA1+-DPB1等位基因的匹配率,e/4相合的比例最高(51.4%),4/4相合的比例仅为5.6%,而0/4相合的比例为8.3%。结论HLA-A、-B、-C、~DRB1和-DQB1等位基因相合的无关供-受者对HLA-DPA1和-DPB1基因匹配率尚较低,HLA-DPA1和-DPB1基因匹配程度对无关供者造血干细胞移植的影响应引起临床的重视和探讨。 展开更多
关键词 人类白细胞抗原 无关供-受者对 HLA-DPA1 HLA-DPB1 测序分型 匹配程
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