Objective:To identify circulating HPV types among urban Indonesian women and their specific co-infection patterns in bid to curb HPV infection in the general population and minimize its complications.Methods:Urban Ind...Objective:To identify circulating HPV types among urban Indonesian women and their specific co-infection patterns in bid to curb HPV infection in the general population and minimize its complications.Methods:Urban Indonesian women from general population were selected as sample framework.Sample size and distribution across regions were determined by the Indonesian Bureau of Statistics(Badan Pusat Statistik,BPS),which represented the national level.Up to 35408 cervical swab specimens were collected from August to September 2016 in 34 Indonesian provinces,categorized into six regions based on the development criteria set by the Ministry of National Development Planning(Badan Perencanaan Pembangunan Nasional,BAPPENAS).From all 1874 samples identified as HPV-positive,hybrid capture was implemented to evaluate type-specific HPV.This study analyzed descriptive data to determine the core-cluster of HPV combination.Co-occurrence HPV network was assessed using‘qgraph’package version 1.6.3 and computed in R version 3.6.3.Two-HPV association was analyzed in logistic regression using bias-reduction generalized linear model(brglm2)package version 0.5.1 adjusted by age and six main Indonesian regions.Results:The logistic regression analysis demonstrated that HPV type 52 had rare relationship despite its common co-occurrence,cementing its role in single HPV infection.HPV type 16 and 18 tended to form infection cluster and were strongly associated with other types.Conclusions:HPV type 52 was the most frequent HPV type among urban Indonesian women and accounted for most single infection cases.Concurrently,HPV 16 and HPV 18 accounted for most multiple infection cases and had strong tendency to attract other types,which may add further complications.However,due to lack of cytology and histological examination and information for other potential determinants,further in-depth studies are necessary to confirm whether these infection patterns truly connect to certain clinical outcomes.展开更多
Few studies have been conducted to assess the level of physical activity(PA)of women in China.The purpose of this study was to describe the prevalence of PA among women in Wuhan and explore sociodemographic and behavi...Few studies have been conducted to assess the level of physical activity(PA)of women in China.The purpose of this study was to describe the prevalence of PA among women in Wuhan and explore sociodemographic and behavioral correlation to PA for the population.A total of 1359 community-dwelling women(42.97�13.60 years old)participated in this study.The long-version IPAQ was used to define the level of PA.45.7%of women were considered physically active,and 27.5%were vigorously active.The proportion of physical inactivity was around 26.8%.The total and 4 domains of PA showed significant age,education level,and occupation variation.PA tended to be lower as the age declined.PA in transportation,housework,leisure time,and the total tended to be the lowest or the second lowest among the women aged 18–35 years old.PA tended to be lower as the level of education increased.Among the 5 indices,PA was the lowest among women with college education,especially those with postgraduate education.PA tended to be the lowest among the women of office staff and instructor or technician.Generally,the total and 4 domains of PA showed significant age,education level,and occupation variation.Physical inactivity appears to be more common among younger women,or college-educated women,office ladies,and female instructor and technicians.展开更多
A serological survey conducted among 196 pregnant women resident in and around Maiduguri, an urban town in north eastern Nigeria showed that 33 (16.8%) were asymptomatic carriers of hepatitis B virus surface antigen (...A serological survey conducted among 196 pregnant women resident in and around Maiduguri, an urban town in north eastern Nigeria showed that 33 (16.8%) were asymptomatic carriers of hepatitis B virus surface antigen (HBsAg). They are within the age range of 14-40 years with mean (± SD) age of 24.7 (± 6.3). The women attend antenatal clinic at the State Specialist Hospital, a secondary health facility in Maiduguri, Borno state. The women are all heterosexuals. The distribution of HBsAg carrier rate according to age of women studied showed a significant (p = 0.0061) increase of the prevalence of HBsAg from 4 (8.7%) in the lower age group (39 years). According to the number of pregnancies, the prevalence of HBsAg infection increased significantly from 6 (9.2%) among primiparous to 13 (13.7%) and 14 (38.9%) among multiparous and grand multiparous respectively. The carrier rate of HBsAg infection among the pregnant women studied based on their duration of pregnancies and their social class showed no significant differences. However, according to the factors known to be commonly associated with the highest risk of transmission of HBV such as history of blood transfusion, Tribal marks/tattooing, use of sharps, sharing of articles, history of jaundice in the women and husbands, history of sexually transmitted infections (STIs) of the women and husbands and the type of marriage (monogamous or polygamous), number of sexual relationships per week, only the history of blood transfusion was significantly associated with HBsAg carrier rate (RR = 3.71., 95% Confidence Interval (C.I.), 1.89-7.30, p = 0.0078). The study confirms that pregnant women who attend antenatal clinic in this secondary health facility are at higher risk of being infected with the HBV, which could lead to both prenatal and post natal transmission to their newborns.展开更多
基金Ministry of Health,Republic of Indonesia provided financial assistance to support this study from their annual budget allocation.
文摘Objective:To identify circulating HPV types among urban Indonesian women and their specific co-infection patterns in bid to curb HPV infection in the general population and minimize its complications.Methods:Urban Indonesian women from general population were selected as sample framework.Sample size and distribution across regions were determined by the Indonesian Bureau of Statistics(Badan Pusat Statistik,BPS),which represented the national level.Up to 35408 cervical swab specimens were collected from August to September 2016 in 34 Indonesian provinces,categorized into six regions based on the development criteria set by the Ministry of National Development Planning(Badan Perencanaan Pembangunan Nasional,BAPPENAS).From all 1874 samples identified as HPV-positive,hybrid capture was implemented to evaluate type-specific HPV.This study analyzed descriptive data to determine the core-cluster of HPV combination.Co-occurrence HPV network was assessed using‘qgraph’package version 1.6.3 and computed in R version 3.6.3.Two-HPV association was analyzed in logistic regression using bias-reduction generalized linear model(brglm2)package version 0.5.1 adjusted by age and six main Indonesian regions.Results:The logistic regression analysis demonstrated that HPV type 52 had rare relationship despite its common co-occurrence,cementing its role in single HPV infection.HPV type 16 and 18 tended to form infection cluster and were strongly associated with other types.Conclusions:HPV type 52 was the most frequent HPV type among urban Indonesian women and accounted for most single infection cases.Concurrently,HPV 16 and HPV 18 accounted for most multiple infection cases and had strong tendency to attract other types,which may add further complications.However,due to lack of cytology and histological examination and information for other potential determinants,further in-depth studies are necessary to confirm whether these infection patterns truly connect to certain clinical outcomes.
文摘Few studies have been conducted to assess the level of physical activity(PA)of women in China.The purpose of this study was to describe the prevalence of PA among women in Wuhan and explore sociodemographic and behavioral correlation to PA for the population.A total of 1359 community-dwelling women(42.97�13.60 years old)participated in this study.The long-version IPAQ was used to define the level of PA.45.7%of women were considered physically active,and 27.5%were vigorously active.The proportion of physical inactivity was around 26.8%.The total and 4 domains of PA showed significant age,education level,and occupation variation.PA tended to be lower as the age declined.PA in transportation,housework,leisure time,and the total tended to be the lowest or the second lowest among the women aged 18–35 years old.PA tended to be lower as the level of education increased.Among the 5 indices,PA was the lowest among women with college education,especially those with postgraduate education.PA tended to be the lowest among the women of office staff and instructor or technician.Generally,the total and 4 domains of PA showed significant age,education level,and occupation variation.Physical inactivity appears to be more common among younger women,or college-educated women,office ladies,and female instructor and technicians.
文摘A serological survey conducted among 196 pregnant women resident in and around Maiduguri, an urban town in north eastern Nigeria showed that 33 (16.8%) were asymptomatic carriers of hepatitis B virus surface antigen (HBsAg). They are within the age range of 14-40 years with mean (± SD) age of 24.7 (± 6.3). The women attend antenatal clinic at the State Specialist Hospital, a secondary health facility in Maiduguri, Borno state. The women are all heterosexuals. The distribution of HBsAg carrier rate according to age of women studied showed a significant (p = 0.0061) increase of the prevalence of HBsAg from 4 (8.7%) in the lower age group (39 years). According to the number of pregnancies, the prevalence of HBsAg infection increased significantly from 6 (9.2%) among primiparous to 13 (13.7%) and 14 (38.9%) among multiparous and grand multiparous respectively. The carrier rate of HBsAg infection among the pregnant women studied based on their duration of pregnancies and their social class showed no significant differences. However, according to the factors known to be commonly associated with the highest risk of transmission of HBV such as history of blood transfusion, Tribal marks/tattooing, use of sharps, sharing of articles, history of jaundice in the women and husbands, history of sexually transmitted infections (STIs) of the women and husbands and the type of marriage (monogamous or polygamous), number of sexual relationships per week, only the history of blood transfusion was significantly associated with HBsAg carrier rate (RR = 3.71., 95% Confidence Interval (C.I.), 1.89-7.30, p = 0.0078). The study confirms that pregnant women who attend antenatal clinic in this secondary health facility are at higher risk of being infected with the HBV, which could lead to both prenatal and post natal transmission to their newborns.
