This study was designed to evaluate the efficacy of local litholytic irrigation (LLI) in the treatment of ureteral uric acid calculi. Fourteen cases of ureteral uric acid calculi were diagnosed by abdominal plain radi...This study was designed to evaluate the efficacy of local litholytic irrigation (LLI) in the treatment of ureteral uric acid calculi. Fourteen cases of ureteral uric acid calculi were diagnosed by abdominal plain radiography (KUB),retrograde urography,ultrasonography(B-mode ultrasound),spiral computerized tomography(CT) and blood biochemical examinations. A ureteral catheter was passed retrogradely across ureteral calculi by cystoscopy. LLI with tromethamine-E(THAM-E) was performed via the ureteral catheter after the improvement of renal function and general situation and the control of urinary tract infection under the condition of intravenous application of antibiotics. The irrigation rate varied from 1000 to 1500 ml per day. Retrograde pyelography demonstrated complete dissolution of all the stones,13 cases within 10 days and 1 within 12 days. Mild hematuria was observed in the majority of the cases and temporary aggravated lumbago in 1 case,with no other side effects. It is concluded that LLI is a practical and effective method in the treatment of ureteral uric acid calculi for its advantages of shorter duration,lower cost,less physical suffering and no severe complications.展开更多
目的探讨单源能谱CT在分析体内泌尿系结石成分中的应用价值。方法对2013年5月~2014年6月间在我院就诊的100例结石患者进行单源能谱128层CT扫描,采集80 k V/140 k V双能量数据,在后处理工作站分析结石成分,并与手术后红外光谱分析结石成...目的探讨单源能谱CT在分析体内泌尿系结石成分中的应用价值。方法对2013年5月~2014年6月间在我院就诊的100例结石患者进行单源能谱128层CT扫描,采集80 k V/140 k V双能量数据,在后处理工作站分析结石成分,并与手术后红外光谱分析结石成分的结果比较,计算单源能谱CT分析在体尿酸盐及非尿酸盐结石的准确性、特异性、敏感性、阳性预测值和阴性预测值。结果单源能谱CT分析110枚结石,含尿酸盐结石20枚（其中纯尿酸盐结石9枚）,非尿酸盐结石90枚;以红外光谱结果为参照,单源能谱CT显示结石含尿酸盐成分的灵敏度、特异度、准确度分别为90.0%、98.9%、97.3%,阳性预测值为95.0%,阴性预测值为97.8%。结论128层CT搭载单源能谱技术平台能准确地区分体内泌尿系结石的尿酸盐和非尿酸盐成分;治疗前预测结石的成分为临床医生选择最佳治疗方案提供了一种全新的检查手段。展开更多
文摘This study was designed to evaluate the efficacy of local litholytic irrigation (LLI) in the treatment of ureteral uric acid calculi. Fourteen cases of ureteral uric acid calculi were diagnosed by abdominal plain radiography (KUB),retrograde urography,ultrasonography(B-mode ultrasound),spiral computerized tomography(CT) and blood biochemical examinations. A ureteral catheter was passed retrogradely across ureteral calculi by cystoscopy. LLI with tromethamine-E(THAM-E) was performed via the ureteral catheter after the improvement of renal function and general situation and the control of urinary tract infection under the condition of intravenous application of antibiotics. The irrigation rate varied from 1000 to 1500 ml per day. Retrograde pyelography demonstrated complete dissolution of all the stones,13 cases within 10 days and 1 within 12 days. Mild hematuria was observed in the majority of the cases and temporary aggravated lumbago in 1 case,with no other side effects. It is concluded that LLI is a practical and effective method in the treatment of ureteral uric acid calculi for its advantages of shorter duration,lower cost,less physical suffering and no severe complications.
文摘目的探讨单源能谱CT在分析体内泌尿系结石成分中的应用价值。方法对2013年5月~2014年6月间在我院就诊的100例结石患者进行单源能谱128层CT扫描,采集80 k V/140 k V双能量数据,在后处理工作站分析结石成分,并与手术后红外光谱分析结石成分的结果比较,计算单源能谱CT分析在体尿酸盐及非尿酸盐结石的准确性、特异性、敏感性、阳性预测值和阴性预测值。结果单源能谱CT分析110枚结石,含尿酸盐结石20枚（其中纯尿酸盐结石9枚）,非尿酸盐结石90枚;以红外光谱结果为参照,单源能谱CT显示结石含尿酸盐成分的灵敏度、特异度、准确度分别为90.0%、98.9%、97.3%,阳性预测值为95.0%,阴性预测值为97.8%。结论128层CT搭载单源能谱技术平台能准确地区分体内泌尿系结石的尿酸盐和非尿酸盐成分;治疗前预测结石的成分为临床医生选择最佳治疗方案提供了一种全新的检查手段。
文摘目的分析上尿路尿酸结石与代谢综合征(metabolic syndrome,MetS)的关系。方法回顾性分析了莒南县人民医院、青岛大学附属医院、临沂市肿瘤医院共计939例上尿路结石患者,使用结石光谱自动分析系统将结石分为含尿酸类结石、含钙类结石、感染性结石、其他类型结石。按MetS诊断标准将患者分为MetS组及非MetS组,比较两组患者所患结石成分的差异。结果MetS组中尿酸类结石明显高于非MetS组(32.58%vs 17.66%),差异有统计学意义(P<0.001)。非MetS组中钙类结石及感染性结石明显高于MetS组,差异有统计学意义。多因素logistics分析显示,代谢综合征相比较非代谢综合征患者发生尿酸类结石的风险高2.22倍(95%CI1.59~3.11,P<0.001),其中腹型肥胖、高血糖、甘油三酯(triacylglycerol,TG)升高、高密度脂蛋白(high density lipoprotein,HDL)降低是尿酸结石形成的危险因素。结论上尿路尿酸结石与MetS密切相关,腹型肥胖、高血糖、高TG、低HDL是尿酸结石形成的危险因素。
