Survey of spinal cord injury-induced neurogenic bladder studies using the Web of Science

OBJECTIVE：To identify global trends in research on spinal cord injury-induced neurogenic bladder, through a bibliometric analysis using the Web of Science. DATA RETRIEVAL：We performed a bibliometric analysis of studies on spinal cord injury-induced neurogenic bladder using the Web of Science.Data retrieval was performed using key words＂spinal cord injury＂,＂spinal injury＂,＂neurogenic bladder＂,＂neuropathic bladder＂,＂neurogenic lower urinary tract dysfunction＂,＂neurogenic voiding dysfunction＂,＂neurogenic urination disorder＂and ＂neurogenic vesicourethral dysfunction＂. SELECTION CRITERIA：Inclusion criteria：（a）published peer-reviewed articles on spinal cord injury-induced neurogenic bladder indexed in the Web of Science;（b）type of articles：original research articles and reviews;（c）year of publication：no limitation.Exclusion criteria：（a）articles that required manual searching or telephone access;（b）Corrected papers and book chapters. MAIN OUTCOME MEASURES：（1）Annual publication output;（2）distribution according to journals; （3）distribution according to subject areas;（4）distribution according to country;（5）distribution according to institution;and（6）top cited publications. RESULTS：There were 646 research articles addressing spinal cord injury-induced neurogenic bladder in the Web of Science.Research on spinal cord injury-induced neurogenic bladder was found in the Science Citation Index-Expanded as of 1946.The United States,Ireland and Switzerland were the three major countries contributing to studies in spinal cord injury-induced neurogenic bladder in the 1970s.However,in the 1990s,the United States,the United Kingdom,the Netherlands,Germany and Japan published more papers on spinal cord injury-induced neurogenic bladder than Switzerland,and Ireland fell off the top ten countries list.In this century,the United States ranks first in spinal cord injury-induced neurogenic bladder studies,followed by France,the United Kingdom,Germany,Switzerland and Japan.Subject categories including urology, nephrology and clinical neurology,as well as rehabilitation,are represented in spinal cord injury-induced neurogenic bladder studies. CONCLUSION：From our analysis of the literature and research trends,we conclude that spinal cord injury-induced neurogenic bladder is a hot topic that will continue to generate considerable research interest in the future.

Investigation of Urination Disorder in Parkinson＇s Disease

Background： Urination disorders are common in Parkinson＇s disease （PD） and respond poorly to medication. This study aimed to analyze the risk factors for urination disorders in PD. Methods： Ninety-one patients with PD （aged 34-83 years old） were recruited. Patients were assessed with the Unified PD Rating Scale （UPDRS）, Hoehn and Yahr stage, Pittsburgh Sleep Quality Index （PSQ1）, Hamilton Depression Rating Scale （HAMD）, and Hamilton Anxiety Scale （HAMA）. Micturition number was recorded, and Type B ultrasound was used to evaluate residual urine. Statistics was performed using binary logistic regression, bivariate correlations, and Chi-square and t-tests. Results： Of 91 patients, urinary dysfunction occurred in 55.0%. Among these, 49.5% suffered with nocturia, 47.3% with pollakiuria. Nocturia number had a positive linear relationship with HAMA score （odds ratio [OR] = 0.340, P = 0.001 ）, HAMD score （OR = 0.323, P = 0.002）, duration of L-dopa medication （OR = 0.328, P = 0.001 ）, dose of L-dopa （OR = 0.273, P = 0.009）, UPDRS-II （OR = 0.402, P = 0.000）, UPDRS-III score （OR = 0.291, P = 0.005）, and PSQI score （OR = 0.249, P = 0.017）. Micturition number over 24 h was positively associated with HAMA （OR = 0.303, P = 0.004） and UPDRS-II scores （OR = 0.306, P = 0.003）. Of patients with residual urine, 79.3% had a volume of residual urine 〈50 ml. Residual urine was present in 44.4% of the patients with nocturia~ 46.5% of the patients with pollakiuria, and 80.0% of the patients with dysuria. More men than women had residual urine （35.2% male vs. 13.3% female; P = 0.002）. Conclusions： Nocturia and pollakiuria were common micturition symptoms in our participants with PD. Nocturia was associated with depression, anxiety, sleep problems, and severity of PD. Pollakiuria was associated with anxiety and severity of PD. Male patients were more prone to residual urine and pollakiuria.