During the underground mining of coal resources,overlying rocks on the roof of excavated tunnels will be destroyed due to ground pressure,and as a result,part of them will break and fall into the tunnels.How to determ...During the underground mining of coal resources,overlying rocks on the roof of excavated tunnels will be destroyed due to ground pressure,and as a result,part of them will break and fall into the tunnels.How to determine the distribution of fractured areas and fissures presents a major problem for preserving the overlying aquifer.展开更多
Neurological disorders are amongst the most widely studied human aliments.Yet,they are also one of the most poorly understood.Although most of these disorders are polygenic,genotype still plays an important role in th...Neurological disorders are amongst the most widely studied human aliments.Yet,they are also one of the most poorly understood.Although most of these disorders are polygenic,genotype still plays an important role in their etiologies.For example,in schizophrenia and autism spectrum disorders,there is a 40-60%concordance rate in monozygotic twins,with 60-90%heritability(Burmeister et al.,2008).However,the mechanisms by which multiple genes and their genomic variations influence the phenotypes of the disorders remain to be understood. The complexities of the disorders are tur- ther compounded by the individual rarity of the genomic variations and their variable penetrance (Cook and Scherer, 2008). Thus, conventional disease modeling, such as gene knockout in cells or in animals, to attain the desired disease genotype may not be the most suitable platform for tackling most neurological disorders.展开更多
Three kinds of methods, i. e., explicit, semi-implicit, and semi-implicit and semi-Lagrangian method, are tested in the time-integration of shallow-water equations on rotating sphere. Helpful results are available fro...Three kinds of methods, i. e., explicit, semi-implicit, and semi-implicit and semi-Lagrangian method, are tested in the time-integration of shallow-water equations on rotating sphere. Helpful results are available from experiments, especially about the accuracy and efficiency of different semi-implicit and semi-Lagrangian schemes.展开更多
The structure, fabrication and emission characteristics of a silicon cold micro-cathode using ultra-shallow PN+ junction are presented. Implantation of As+ with a energy around 12 kev, rapid thermal annealing combined...The structure, fabrication and emission characteristics of a silicon cold micro-cathode using ultra-shallow PN+ junction are presented. Implantation of As+ with a energy around 12 kev, rapid thermal annealing combined with argon sputtering are used for forming ultra-shallow pn+ junction, whose depth is lower than 30nm. In a vacuum system Ⅰ-Ⅴcharacteristics were measured. The stability problem which was found in the devices testing is also discussed in this paper.展开更多
After primary analyses on the serum glycocon-jugates of lung cancer and normal individul using the enzyme-linked lectin assay (ELLA) with 12 kinds of lectins, PHA and LCA were selected to further study in the sera of ...After primary analyses on the serum glycocon-jugates of lung cancer and normal individul using the enzyme-linked lectin assay (ELLA) with 12 kinds of lectins, PHA and LCA were selected to further study in the sera of 8 kinds of cancers, 4 kinds of non-malignant disease and 1 kind of postoperative cancer. It was found that the test values of 7 kinds of cancers with PHA or LCA were significantly higher than that of the normal (P<0.01); the values of 4 kinds of non-malignant diseases with PHA were not higher (P>0.05); the values of the postoperative cancer with PHA were obviously lower than that of the preoperative (P<0.05). The results showed that the serum glycoconjugates which can bind to PHA seemed related to the cancerous existence in human bodies. The significance of the findings was discussed.展开更多
Ⅰ The Indexes of Detecting Oil and Gas Resources The deeply buried reservoir which in a dynamic equilibrium state has a great pressure inside, and between it and earth surface there is a great difference of pressure....Ⅰ The Indexes of Detecting Oil and Gas Resources The deeply buried reservoir which in a dynamic equilibrium state has a great pressure inside, and between it and earth surface there is a great difference of pressure. Therefore the hydrocarbon must spread and move vertically to the surface along the pressure gradient orientation. Hydrocarbons in the reservoir along some small rifts, cracks, joints and cleavages penetrate the overlying strata and seepage onto the surface. Thus the hydrocarbons become unvisble oil and gas signs. This process is called the phenomena of hydrocarbon microseepage of reservoir. Hydrocarbons microseepage in the process展开更多
The study area is located between the cities of Comitan (16°10'43"N and 92°04'20''W) a city with 150,000 inhabitants and La Esperanza (16°9'15''N and 91°...The study area is located between the cities of Comitan (16°10'43"N and 92°04'20''W) a city with 150,000 inhabitants and La Esperanza (16°9'15''N and 91°52'5''W) a town with 3000 inhabitants. Both weather stations are 30 km from each other in the Chiapas State, México. 54 years of daily records of the series of maximum (<em>t</em><sub>max</sub>) and minimum temperatures (<em>t</em><sub>min</sub>) of the weather station 07205 Comitan that is on top of a house and 30 years of daily records of the weather station 07374 La Esperanza were analyzed. The objective is to analyze the evidence of climate change in the Comitan valley. 2.07% and 19.04% of missing data were filled, respectively, with the WS method. In order to verify homogeneity three methods were used: Standard Normal Homogeneity Test (SNHT), the Von Neumann method and the Buishand method. The heterogeneous series were homogenized using climatol. The trends of <em>t</em><sub>max</sub> and <em>t</em><sub>min</sub> for both weather stations were analyzed by simple linear regression, Sperman’s rho and Mann-Kendall tests. The Mann-Kendal test method confirmed the warming trend at the Comitan station for both variables with <em>Z<sub>MK</sub></em> statistic values equal to 1.57 (statistically not significant) and 4.64 (statistically significant). However, for the Esperanza station, it determined a cooling trend for tmin and a slight non-significant warming for <em>t</em><sub>max</sub> with a <em>Z</em><sub><em>MK</em></sub> statistic of -2.27 (statistically significant) and 1.16 (statistically not significant), for a significance level <em>α</em> = 0.05.展开更多
Progress in developing robust therapies for spinal cord injury (SCI), trau- matic brain injury (TBI) and peripheral nerve injury has been slow. A great deal has been learned over the past 30 years regarding both t...Progress in developing robust therapies for spinal cord injury (SCI), trau- matic brain injury (TBI) and peripheral nerve injury has been slow. A great deal has been learned over the past 30 years regarding both the intrinsic factors and the environmental factors that regulate axon growth, but this large body of information has not yet resulted in clinically available thera- peutics. This therapeutic bottleneck has many root causes, but a consensus is emerging that one contributing factor is a lack of standards for experi- mental design and reporting. The absence of reporting standards, and even of commonly accepted definitions of key words, also make data mining and bioinformatics analysis of neural plasticity and regeneration difficult, if not impossible. This short review will consider relevant background and poten- tial solutions to this problem in the axon regeneration domain.展开更多
Commentary Most would agree that providing comprehensive detail in scientific reporting is critical for the development of mean- ingful therapies and treatments for diseases. Such stellar practices 1) allow for repro...Commentary Most would agree that providing comprehensive detail in scientific reporting is critical for the development of mean- ingful therapies and treatments for diseases. Such stellar practices 1) allow for reproduction of experiments to con- firm results, 2) promote thorough analyses of data, and 3) foster the incremental advancement of valid approaches. Unfortunately, most would also agree we have far to go to reach this vital goal (Hackam and Redelmeier, 2006; Prinz et al., 2011; Baker et al., 2014).展开更多
Scanning tunnel microscopy (STM) is performed to verify if an Rh 'nails' structure is formed accompanying the graphene growing during chemical vapor deposition. A structure of a graphene island in an Rh vacancy is...Scanning tunnel microscopy (STM) is performed to verify if an Rh 'nails' structure is formed accompanying the graphene growing during chemical vapor deposition. A structure of a graphene island in an Rh vacancy island is used as the start. While the graphene island is removed by oxygenation, the variations of the Rh vacancy island are imaged with an in-situ high-temperature STM. By fitting with our model and calculations, we conclude that the best fit is obtained for 0% Rh, i.e., for the complete absence of nails below graphene on Rh(111). That is, when graphene is formed on Rh(111), the substrate remains fiat and does not develop a SUPPorting nail structure.展开更多
The practice of stimulating follicular develop-ment by Shen-invigorating herbs is directed by tra-ditional Chinese medical theories of“the Shenstores essence of life and governs reproduction”
Progress in computational fluid dynamics in the field of turbomachine cascades has increased recently the importance of the study by cascade wind tunnels to verify various newly introduced concepts. A transonic cascad...Progress in computational fluid dynamics in the field of turbomachine cascades has increased recently the importance of the study by cascade wind tunnels to verify various newly introduced concepts. A transonic cascade wind tunnel test facility has been built for this purpose in the Department of Aeronautics, University of Tokyo. The system and operation of this facility will be explained in detail. The tunnel is of blowdown type, and can be run repeatedly at a short interval. Experimental cascade performances obtained by this facility as well as numerical results for cascades designed along new concepts are discussed.展开更多
Beneficiation study on samples of baryte ore from Azare in the Plateau State of Nigeria was carried out using chemical analysis, atomic absorption spectrophotometric analysis, jigging and magnetic separation. Results...Beneficiation study on samples of baryte ore from Azare in the Plateau State of Nigeria was carried out using chemical analysis, atomic absorption spectrophotometric analysis, jigging and magnetic separation. Results show that Azare baryte can profitably be concentrated for use in oil drilling and other industrial purposes. Barium sulphate content in the head ore analyzed, is 98%. Comparison between jigging and magnetic separation shows that jigging produces a more satisfactory result.展开更多
China’s first general standard for stem cells officially released on November 22,2017 is expected to lay a foundation for regulating the application of stem cells technology.Stem cells are a group of self-renewal cel...China’s first general standard for stem cells officially released on November 22,2017 is expected to lay a foundation for regulating the application of stem cells technology.Stem cells are a group of self-renewal cells that can differentiate into specialized cells.They are now used for the treatment of many diseases.Despite a series of documents for regulating basic research and achievement transformation of stem cells,展开更多
This paper selects some representative regions to obtain their G-R relation curves according to their seismicity characteristics,by using ML≥2.0 microseismicity data(1970~1993)in North China.The annual occurrence rat...This paper selects some representative regions to obtain their G-R relation curves according to their seismicity characteristics,by using ML≥2.0 microseismicity data(1970~1993)in North China.The annual occurrence rate of events of each magnitude can be inferred from the G-R relation.At the same tune,the actual annual occurrence rate of earthquakes of higher magnitudes can be calculated from historical earthquakes(1300-1993)recorded in the same region.It seems that both results are almost the same.Therefore,the rate of events of higher magnitudes can be obtained by using microseismicity data when the proper region is selected.However,two points should be noticed:(1)The method can only give the annual occurrence rate in a seismicity system and estimate the whole situation of the system.(2)When there is a very large earthquake in and near the period in which the microseismicity data are applied,the actual occurrence rate of the system,including this larger earthquake,cannot be obtained by this method.展开更多
To measure breast basic dimension by using computer-aided projection fringe system.Methods A system has been developed for measuring breast basic dimension based on computer-aided projection fringe measurement and pro...To measure breast basic dimension by using computer-aided projection fringe system.Methods A system has been developed for measuring breast basic dimension based on computer-aided projection fringe measurement and programming software.Plastic manikins breast’s SN-N (sternal notch to nipple distance),N-ML (nipple to midline distance),N-N (internipple distance),MBW (base width of breast) and N-IMF (nipple to inframammary fold distance) are measured with this system.At the same time,these items are also measured with routine ruler.Results This study indicate that the system has some merits:① non-touching measurement;② it is very rapid,the patient measured need hold his breath only 0.5 second,and all the time it takes is about 2.5 minutes;③ the measurement’s sensitivity is as high as to 0.6 mm,which meets the clinic requirement entirely;④ the measurement’s accuracy of the system is not significantly when comparing to the routine ruler’s.Conclusion Computer-adided projection fringe system for measuring breast basic dimension is feasible and advanced.14 refs,1 fig.展开更多
Crosstalk in FBG-MOC-based OXCs is simulated using scattering parameters and compared with that in FBG-OC-based OXCs. The former is able to enhance the output power without significant degradation in signal-to-crossta...Crosstalk in FBG-MOC-based OXCs is simulated using scattering parameters and compared with that in FBG-OC-based OXCs. The former is able to enhance the output power without significant degradation in signal-to-crosstalk ratio compared with the latter.展开更多
基金supported by the State Key Program of National Natural Science of China(Grant No.41130637)
文摘During the underground mining of coal resources,overlying rocks on the roof of excavated tunnels will be destroyed due to ground pressure,and as a result,part of them will break and fall into the tunnels.How to determine the distribution of fractured areas and fissures presents a major problem for preserving the overlying aquifer.
文摘Neurological disorders are amongst the most widely studied human aliments.Yet,they are also one of the most poorly understood.Although most of these disorders are polygenic,genotype still plays an important role in their etiologies.For example,in schizophrenia and autism spectrum disorders,there is a 40-60%concordance rate in monozygotic twins,with 60-90%heritability(Burmeister et al.,2008).However,the mechanisms by which multiple genes and their genomic variations influence the phenotypes of the disorders remain to be understood. The complexities of the disorders are tur- ther compounded by the individual rarity of the genomic variations and their variable penetrance (Cook and Scherer, 2008). Thus, conventional disease modeling, such as gene knockout in cells or in animals, to attain the desired disease genotype may not be the most suitable platform for tackling most neurological disorders.
文摘Three kinds of methods, i. e., explicit, semi-implicit, and semi-implicit and semi-Lagrangian method, are tested in the time-integration of shallow-water equations on rotating sphere. Helpful results are available from experiments, especially about the accuracy and efficiency of different semi-implicit and semi-Lagrangian schemes.
文摘The structure, fabrication and emission characteristics of a silicon cold micro-cathode using ultra-shallow PN+ junction are presented. Implantation of As+ with a energy around 12 kev, rapid thermal annealing combined with argon sputtering are used for forming ultra-shallow pn+ junction, whose depth is lower than 30nm. In a vacuum system Ⅰ-Ⅴcharacteristics were measured. The stability problem which was found in the devices testing is also discussed in this paper.
文摘After primary analyses on the serum glycocon-jugates of lung cancer and normal individul using the enzyme-linked lectin assay (ELLA) with 12 kinds of lectins, PHA and LCA were selected to further study in the sera of 8 kinds of cancers, 4 kinds of non-malignant disease and 1 kind of postoperative cancer. It was found that the test values of 7 kinds of cancers with PHA or LCA were significantly higher than that of the normal (P<0.01); the values of 4 kinds of non-malignant diseases with PHA were not higher (P>0.05); the values of the postoperative cancer with PHA were obviously lower than that of the preoperative (P<0.05). The results showed that the serum glycoconjugates which can bind to PHA seemed related to the cancerous existence in human bodies. The significance of the findings was discussed.
文摘Ⅰ The Indexes of Detecting Oil and Gas Resources The deeply buried reservoir which in a dynamic equilibrium state has a great pressure inside, and between it and earth surface there is a great difference of pressure. Therefore the hydrocarbon must spread and move vertically to the surface along the pressure gradient orientation. Hydrocarbons in the reservoir along some small rifts, cracks, joints and cleavages penetrate the overlying strata and seepage onto the surface. Thus the hydrocarbons become unvisble oil and gas signs. This process is called the phenomena of hydrocarbon microseepage of reservoir. Hydrocarbons microseepage in the process
文摘The study area is located between the cities of Comitan (16°10'43"N and 92°04'20''W) a city with 150,000 inhabitants and La Esperanza (16°9'15''N and 91°52'5''W) a town with 3000 inhabitants. Both weather stations are 30 km from each other in the Chiapas State, México. 54 years of daily records of the series of maximum (<em>t</em><sub>max</sub>) and minimum temperatures (<em>t</em><sub>min</sub>) of the weather station 07205 Comitan that is on top of a house and 30 years of daily records of the weather station 07374 La Esperanza were analyzed. The objective is to analyze the evidence of climate change in the Comitan valley. 2.07% and 19.04% of missing data were filled, respectively, with the WS method. In order to verify homogeneity three methods were used: Standard Normal Homogeneity Test (SNHT), the Von Neumann method and the Buishand method. The heterogeneous series were homogenized using climatol. The trends of <em>t</em><sub>max</sub> and <em>t</em><sub>min</sub> for both weather stations were analyzed by simple linear regression, Sperman’s rho and Mann-Kendall tests. The Mann-Kendal test method confirmed the warming trend at the Comitan station for both variables with <em>Z<sub>MK</sub></em> statistic values equal to 1.57 (statistically not significant) and 4.64 (statistically significant). However, for the Esperanza station, it determined a cooling trend for tmin and a slight non-significant warming for <em>t</em><sub>max</sub> with a <em>Z</em><sub><em>MK</em></sub> statistic of -2.27 (statistically significant) and 1.16 (statistically not significant), for a significance level <em>α</em> = 0.05.
基金Research in the Lemmon/Bixby lab is supported by NIH grants NS080145 and NS059866by the Miami Project to Cure Paralysis
文摘Progress in developing robust therapies for spinal cord injury (SCI), trau- matic brain injury (TBI) and peripheral nerve injury has been slow. A great deal has been learned over the past 30 years regarding both the intrinsic factors and the environmental factors that regulate axon growth, but this large body of information has not yet resulted in clinically available thera- peutics. This therapeutic bottleneck has many root causes, but a consensus is emerging that one contributing factor is a lack of standards for experi- mental design and reporting. The absence of reporting standards, and even of commonly accepted definitions of key words, also make data mining and bioinformatics analysis of neural plasticity and regeneration difficult, if not impossible. This short review will consider relevant background and poten- tial solutions to this problem in the axon regeneration domain.
文摘Commentary Most would agree that providing comprehensive detail in scientific reporting is critical for the development of mean- ingful therapies and treatments for diseases. Such stellar practices 1) allow for reproduction of experiments to con- firm results, 2) promote thorough analyses of data, and 3) foster the incremental advancement of valid approaches. Unfortunately, most would also agree we have far to go to reach this vital goal (Hackam and Redelmeier, 2006; Prinz et al., 2011; Baker et al., 2014).
基金Supported by the National Natural Science Foundation of China under Grant No 51402026the Basic Research Program of Jiangsu Province under Grant No BK20130236the High Technology Research Key Laboratory of Changzhou under Grant No CM20133007
文摘Scanning tunnel microscopy (STM) is performed to verify if an Rh 'nails' structure is formed accompanying the graphene growing during chemical vapor deposition. A structure of a graphene island in an Rh vacancy island is used as the start. While the graphene island is removed by oxygenation, the variations of the Rh vacancy island are imaged with an in-situ high-temperature STM. By fitting with our model and calculations, we conclude that the best fit is obtained for 0% Rh, i.e., for the complete absence of nails below graphene on Rh(111). That is, when graphene is formed on Rh(111), the substrate remains fiat and does not develop a SUPPorting nail structure.
文摘The practice of stimulating follicular develop-ment by Shen-invigorating herbs is directed by tra-ditional Chinese medical theories of“the Shenstores essence of life and governs reproduction”
文摘Progress in computational fluid dynamics in the field of turbomachine cascades has increased recently the importance of the study by cascade wind tunnels to verify various newly introduced concepts. A transonic cascade wind tunnel test facility has been built for this purpose in the Department of Aeronautics, University of Tokyo. The system and operation of this facility will be explained in detail. The tunnel is of blowdown type, and can be run repeatedly at a short interval. Experimental cascade performances obtained by this facility as well as numerical results for cascades designed along new concepts are discussed.
文摘Beneficiation study on samples of baryte ore from Azare in the Plateau State of Nigeria was carried out using chemical analysis, atomic absorption spectrophotometric analysis, jigging and magnetic separation. Results show that Azare baryte can profitably be concentrated for use in oil drilling and other industrial purposes. Barium sulphate content in the head ore analyzed, is 98%. Comparison between jigging and magnetic separation shows that jigging produces a more satisfactory result.
文摘China’s first general standard for stem cells officially released on November 22,2017 is expected to lay a foundation for regulating the application of stem cells technology.Stem cells are a group of self-renewal cells that can differentiate into specialized cells.They are now used for the treatment of many diseases.Despite a series of documents for regulating basic research and achievement transformation of stem cells,
基金This project was sponsored by the National Natural Science Foundation of China under the contract of No. 49574207
文摘This paper selects some representative regions to obtain their G-R relation curves according to their seismicity characteristics,by using ML≥2.0 microseismicity data(1970~1993)in North China.The annual occurrence rate of events of each magnitude can be inferred from the G-R relation.At the same tune,the actual annual occurrence rate of earthquakes of higher magnitudes can be calculated from historical earthquakes(1300-1993)recorded in the same region.It seems that both results are almost the same.Therefore,the rate of events of higher magnitudes can be obtained by using microseismicity data when the proper region is selected.However,two points should be noticed:(1)The method can only give the annual occurrence rate in a seismicity system and estimate the whole situation of the system.(2)When there is a very large earthquake in and near the period in which the microseismicity data are applied,the actual occurrence rate of the system,including this larger earthquake,cannot be obtained by this method.
文摘To measure breast basic dimension by using computer-aided projection fringe system.Methods A system has been developed for measuring breast basic dimension based on computer-aided projection fringe measurement and programming software.Plastic manikins breast’s SN-N (sternal notch to nipple distance),N-ML (nipple to midline distance),N-N (internipple distance),MBW (base width of breast) and N-IMF (nipple to inframammary fold distance) are measured with this system.At the same time,these items are also measured with routine ruler.Results This study indicate that the system has some merits:① non-touching measurement;② it is very rapid,the patient measured need hold his breath only 0.5 second,and all the time it takes is about 2.5 minutes;③ the measurement’s sensitivity is as high as to 0.6 mm,which meets the clinic requirement entirely;④ the measurement’s accuracy of the system is not significantly when comparing to the routine ruler’s.Conclusion Computer-adided projection fringe system for measuring breast basic dimension is feasible and advanced.14 refs,1 fig.
文摘Crosstalk in FBG-MOC-based OXCs is simulated using scattering parameters and compared with that in FBG-OC-based OXCs. The former is able to enhance the output power without significant degradation in signal-to-crosstalk ratio compared with the latter.