Background: The success rate of vaginal birth after cesarean section with a single cesarean scar is greater than 50%, the lack of the information about the safety of vaginal birth after cesarean delivery pushes most o...Background: The success rate of vaginal birth after cesarean section with a single cesarean scar is greater than 50%, the lack of the information about the safety of vaginal birth after cesarean delivery pushes most of obstetricians to increase the num ber of cesarean sections following a previous cesarean section. Guidelines for Vaginal birth after cesarean (VBAC) indicate that TOLAC offers women with no contraindications and one previous transverse low-segment cesarean. The objective of the current study was to study the outcome of trial of labour after caesarean section (TOLAC), the indications for emergency repeat cesarean section and to determine the maternal and fetal prognosis in vaginal birth after caesarian section (VBAC) at Tshikaji Mission Hospital. Patients, Material and Methods: This is a retrospective study of the records of 126 women were selected to undergo the TOLAC in the department of gynecology and obstetrics at the Tshikaji Mission Hospital over the period from January 1<sup>st</sup> to December 31<sup>st</sup>, 2021. The data on demography, antenatal care, labour and delivery and outcomes were collected from the maternity unit of this hospital. The data were analyzed using SPSS version 2.0. Results: The TOLAC in 126 studied women. The course of work allowed vaginal delivery 107 parturient women, a success rate of successful VBAC of 85% after the TOLAC. The repeat emergency cesarean section was necessary for delivery in 15% of cases for failed TOLAC. There was no maternal mortality, but we recorded one fetal death or 0.8% of perinatal mortality, 2 cases of cicatricial dehiscence, the incidence of 1.6%. Maternal morbidity after delivery on cicatricial uterus was dominated by postpartum hemorrhages, with 19 cases or 15.1% of cases. Cervical dilatation of more than 3 cm at the time of admission, the parity more than 3 and were the significant factors in favor of a successful VBAC. Birth weight of more than 3500 g, fetal distress and malpresentation were associated with a lower success rate of VBAC. The TOLAC in selected cases has great importance in the present era of the rising rate of primary CS especially in rural areas. Conclusion: Pregnancy on a cicatricial uterus represents a high-risk pregnancy. Trial of VBAC in selected cases has great importance in the present era of the rising rate of primary CS especially in rural areas. There is a significantly high vaginal birth after caesarian section (VBAC) success rate among selected women undergoing trial of scar in Tshikaji Hospital. TOLAC remains the option for childbirth in low resource settings as Kasai region in DRC. Adequate patient education and counselling in addition to appropriate patient selection for TOLAC remain the cornerstone to achieving high VBAC success rate.展开更多
目的探究不同剂量缩宫素(oxytocin,OT)对剖宫产术后再次妊娠经阴道试产(trial of labor after cesareansection,TOLAC)孕妇产程进展、凝血功能和母婴结局的影响。方法回顾性分析138例TOLAC孕妇临床病历资料,根据产程中OT总用量分为低剂...目的探究不同剂量缩宫素(oxytocin,OT)对剖宫产术后再次妊娠经阴道试产(trial of labor after cesareansection,TOLAC)孕妇产程进展、凝血功能和母婴结局的影响。方法回顾性分析138例TOLAC孕妇临床病历资料,根据产程中OT总用量分为低剂量组61例、中剂量组45例和高剂量组32例,比较三组的产程进展、凝血功能、分娩方式、妊娠结局及围产儿结局。结果三组第一产程、第二产程、第三产程及总产程比较,差异均无统计学意义(P>0.05);与用药前比,三组用药后凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)均降低,纤维蛋白原(FIB)水平均升高,差异有统计学意义(P<0.05),三组间用药后PT、APTT、FIB比较差异无统计学意义(P>0.05)。低剂量组及中剂量组孕产妇的胎盘早剥、新生儿高胆红素血症发生率均低于高剂量组,差异有统计学意义(P<0.05)。结论OT可增强TOLAC孕妇子宫收缩力,改善凝血功能,但大剂量OT可能增加胎盘早剥及新生儿高胆红素血症发生风险。展开更多
BACKGROUND Vaginal delivery is the ideal mode of delivery for the termination of a pregnancy.However,the cesarean section rate in China is much higher than the published by the World Health Organization in the Lancet ...BACKGROUND Vaginal delivery is the ideal mode of delivery for the termination of a pregnancy.However,the cesarean section rate in China is much higher than the published by the World Health Organization in the Lancet in 2010.AIM To retrospectively analyze the factors related to failed trial of labor and the clinical indications for cesarean section conversion,explore how to promote the trial of labor success rate,and determine the feasibility of reducing the rate of conversion to cesarean section.METHODS A retrospective analysis was performed on 9240 maternal women who met vaginal delivery conditions and required a trial of labor from January 2016 to December 2018 at our hospital.Among them,8164 pregnant women who had a successful trial of labor were used as a control group,and 1076 pregnant women who had a failed trial of labor and converted to an emergency cesarean section were used as an observation group.The patients’clinical data during hospitalization were collected for comparative analysis,the related factors of the failed trial of labor were discussed,and reasonable prevention and resolution strategies were proposed to increase the success rate of trial of labor.RESULTS The analysis revealed that advanced age(≥35 years old),macrosomia(≥4000 g),delayed pregnancy(≥41 wk),use of uterine contraction drugs,primipara,and fever during labor were associated with conversion to an emergency cesarean section in the failed trial of labor.Multivariate regression analysis showed that age,gestational age,primipara,use of uterine contraction drugs,fever duringbirth,and newborn weight led to a higher probability of conversion to an emergency cesarean section in the failed trial of labor.The analysis indicated that the following clinical indications were associated with the conversion to cesarean section in the failed trial of labor:Fetal distress(44.3%),social factors(12.8%),malpresentation(face presentation,persistent occipitoposterior position,and persistent occipitotransverse position)(9.4%),and cephalopelvic disproportion(8.9%).CONCLUSION The conversion to emergency cesarean section in failed trial of labor is affected by many factors.Medical staff should take appropriate preventive measures for the main factors,increase the trial of labor success rate,improve the quality of delivery,ensure the safety of mother and child during the perinatal period,and improve the relationship between doctors and patients.展开更多
目的:探讨剖宫产术后再次妊娠阴道分娩(vaginal birth after cesarean section,VBAC)成功率的影响因素,指导剖宫产术后再次妊娠阴道试产(trial of labor after cesarean,TOLAC)临床决策,提高VBAC成功率,减少不良母婴结局的发生。方法:...目的:探讨剖宫产术后再次妊娠阴道分娩(vaginal birth after cesarean section,VBAC)成功率的影响因素,指导剖宫产术后再次妊娠阴道试产(trial of labor after cesarean,TOLAC)临床决策,提高VBAC成功率,减少不良母婴结局的发生。方法:回顾性分析2020年1月至2022年10月于重庆医科大学附属妇女儿童医院(重庆市妇幼保健院)产科中心TOLAC孕妇共452例,其中VBAC孕妇342例,TOLAC失败孕妇110例,根据最终分娩方式从各随机选取110例孕妇分为VBAC组和TOLAC失败组。采用单因素分析和多因素Logistic回归分析VBAC的影响因素,并比较2组孕产妇的妊娠结局。结果:①总体VBAC率为75.67%(342/452),TOLAC失败率为24.33%(110/452)。②产前影响因素单因素分析发现,VBAC组与TOLAC失败组孕妇的孕周分别为(38.44±2.13)、(38.96±1.34)周,既往因不良孕产史行引产分别为11.82%、2.80%,存在妊娠合并症为32.73%、20.56%,比较差异有统计学意义(均P<0.05)。入院时宫颈Bishop评分(5.15±1.69、3.71±1.52),既往阴道分娩史(32.73%、20.56%),自然临产(86.36%、17.76%)分别比较,差异也有统计学意义(均P<0.001)。③母婴妊娠结局单因素分析发现,新生儿体质量分别为(3191.82±489.00)、(3334.15±375.9)g,产后24 h出血量分别为(408.75±142.31)、(560.85±168.61)mL,VBAC组均低于TOLAC失败组,差异有统计学意义(均P<0.05)。TOLAC失败组中有7例不全子宫破裂。2组妊娠结局中输血、产褥感染、新生儿5 min Apgar评分的分别比较,差异无统计学意义。无孕产妇及围产儿死亡病例。④多因素Logistic回归分析显示,入院时宫颈Bishop评分(OR=0.122,95%CI=0.010~1.441)、既往阴道分娩史(OR=0.034,95%CI=1.297~715.194)、早产(OR=186.54,95%CI=2.225~15638.578)及自然临产(OR=52.37,95%CI=8.949~306.517)均是VBAC的影响因素。结论:VBAC的影响因素为孕妇的孕周、既往阴道分娩分娩史、既往因不良孕产史引产、存在妊娠合并症、入院时宫颈Bishop评分、自然临产、早产史。VBAC组产后24 h出血量低于TOLAC失败组。展开更多
文摘Background: The success rate of vaginal birth after cesarean section with a single cesarean scar is greater than 50%, the lack of the information about the safety of vaginal birth after cesarean delivery pushes most of obstetricians to increase the num ber of cesarean sections following a previous cesarean section. Guidelines for Vaginal birth after cesarean (VBAC) indicate that TOLAC offers women with no contraindications and one previous transverse low-segment cesarean. The objective of the current study was to study the outcome of trial of labour after caesarean section (TOLAC), the indications for emergency repeat cesarean section and to determine the maternal and fetal prognosis in vaginal birth after caesarian section (VBAC) at Tshikaji Mission Hospital. Patients, Material and Methods: This is a retrospective study of the records of 126 women were selected to undergo the TOLAC in the department of gynecology and obstetrics at the Tshikaji Mission Hospital over the period from January 1<sup>st</sup> to December 31<sup>st</sup>, 2021. The data on demography, antenatal care, labour and delivery and outcomes were collected from the maternity unit of this hospital. The data were analyzed using SPSS version 2.0. Results: The TOLAC in 126 studied women. The course of work allowed vaginal delivery 107 parturient women, a success rate of successful VBAC of 85% after the TOLAC. The repeat emergency cesarean section was necessary for delivery in 15% of cases for failed TOLAC. There was no maternal mortality, but we recorded one fetal death or 0.8% of perinatal mortality, 2 cases of cicatricial dehiscence, the incidence of 1.6%. Maternal morbidity after delivery on cicatricial uterus was dominated by postpartum hemorrhages, with 19 cases or 15.1% of cases. Cervical dilatation of more than 3 cm at the time of admission, the parity more than 3 and were the significant factors in favor of a successful VBAC. Birth weight of more than 3500 g, fetal distress and malpresentation were associated with a lower success rate of VBAC. The TOLAC in selected cases has great importance in the present era of the rising rate of primary CS especially in rural areas. Conclusion: Pregnancy on a cicatricial uterus represents a high-risk pregnancy. Trial of VBAC in selected cases has great importance in the present era of the rising rate of primary CS especially in rural areas. There is a significantly high vaginal birth after caesarian section (VBAC) success rate among selected women undergoing trial of scar in Tshikaji Hospital. TOLAC remains the option for childbirth in low resource settings as Kasai region in DRC. Adequate patient education and counselling in addition to appropriate patient selection for TOLAC remain the cornerstone to achieving high VBAC success rate.
文摘目的探究不同剂量缩宫素(oxytocin,OT)对剖宫产术后再次妊娠经阴道试产(trial of labor after cesareansection,TOLAC)孕妇产程进展、凝血功能和母婴结局的影响。方法回顾性分析138例TOLAC孕妇临床病历资料,根据产程中OT总用量分为低剂量组61例、中剂量组45例和高剂量组32例,比较三组的产程进展、凝血功能、分娩方式、妊娠结局及围产儿结局。结果三组第一产程、第二产程、第三产程及总产程比较,差异均无统计学意义(P>0.05);与用药前比,三组用药后凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)均降低,纤维蛋白原(FIB)水平均升高,差异有统计学意义(P<0.05),三组间用药后PT、APTT、FIB比较差异无统计学意义(P>0.05)。低剂量组及中剂量组孕产妇的胎盘早剥、新生儿高胆红素血症发生率均低于高剂量组,差异有统计学意义(P<0.05)。结论OT可增强TOLAC孕妇子宫收缩力,改善凝血功能,但大剂量OT可能增加胎盘早剥及新生儿高胆红素血症发生风险。
基金Supported by Liaoning Provincial Natural Science Foundation Guidance Program,No.2019-ZD-1037。
文摘BACKGROUND Vaginal delivery is the ideal mode of delivery for the termination of a pregnancy.However,the cesarean section rate in China is much higher than the published by the World Health Organization in the Lancet in 2010.AIM To retrospectively analyze the factors related to failed trial of labor and the clinical indications for cesarean section conversion,explore how to promote the trial of labor success rate,and determine the feasibility of reducing the rate of conversion to cesarean section.METHODS A retrospective analysis was performed on 9240 maternal women who met vaginal delivery conditions and required a trial of labor from January 2016 to December 2018 at our hospital.Among them,8164 pregnant women who had a successful trial of labor were used as a control group,and 1076 pregnant women who had a failed trial of labor and converted to an emergency cesarean section were used as an observation group.The patients’clinical data during hospitalization were collected for comparative analysis,the related factors of the failed trial of labor were discussed,and reasonable prevention and resolution strategies were proposed to increase the success rate of trial of labor.RESULTS The analysis revealed that advanced age(≥35 years old),macrosomia(≥4000 g),delayed pregnancy(≥41 wk),use of uterine contraction drugs,primipara,and fever during labor were associated with conversion to an emergency cesarean section in the failed trial of labor.Multivariate regression analysis showed that age,gestational age,primipara,use of uterine contraction drugs,fever duringbirth,and newborn weight led to a higher probability of conversion to an emergency cesarean section in the failed trial of labor.The analysis indicated that the following clinical indications were associated with the conversion to cesarean section in the failed trial of labor:Fetal distress(44.3%),social factors(12.8%),malpresentation(face presentation,persistent occipitoposterior position,and persistent occipitotransverse position)(9.4%),and cephalopelvic disproportion(8.9%).CONCLUSION The conversion to emergency cesarean section in failed trial of labor is affected by many factors.Medical staff should take appropriate preventive measures for the main factors,increase the trial of labor success rate,improve the quality of delivery,ensure the safety of mother and child during the perinatal period,and improve the relationship between doctors and patients.
文摘目的:探讨剖宫产术后再次妊娠阴道分娩(vaginal birth after cesarean section,VBAC)成功率的影响因素,指导剖宫产术后再次妊娠阴道试产(trial of labor after cesarean,TOLAC)临床决策,提高VBAC成功率,减少不良母婴结局的发生。方法:回顾性分析2020年1月至2022年10月于重庆医科大学附属妇女儿童医院(重庆市妇幼保健院)产科中心TOLAC孕妇共452例,其中VBAC孕妇342例,TOLAC失败孕妇110例,根据最终分娩方式从各随机选取110例孕妇分为VBAC组和TOLAC失败组。采用单因素分析和多因素Logistic回归分析VBAC的影响因素,并比较2组孕产妇的妊娠结局。结果:①总体VBAC率为75.67%(342/452),TOLAC失败率为24.33%(110/452)。②产前影响因素单因素分析发现,VBAC组与TOLAC失败组孕妇的孕周分别为(38.44±2.13)、(38.96±1.34)周,既往因不良孕产史行引产分别为11.82%、2.80%,存在妊娠合并症为32.73%、20.56%,比较差异有统计学意义(均P<0.05)。入院时宫颈Bishop评分(5.15±1.69、3.71±1.52),既往阴道分娩史(32.73%、20.56%),自然临产(86.36%、17.76%)分别比较,差异也有统计学意义(均P<0.001)。③母婴妊娠结局单因素分析发现,新生儿体质量分别为(3191.82±489.00)、(3334.15±375.9)g,产后24 h出血量分别为(408.75±142.31)、(560.85±168.61)mL,VBAC组均低于TOLAC失败组,差异有统计学意义(均P<0.05)。TOLAC失败组中有7例不全子宫破裂。2组妊娠结局中输血、产褥感染、新生儿5 min Apgar评分的分别比较,差异无统计学意义。无孕产妇及围产儿死亡病例。④多因素Logistic回归分析显示,入院时宫颈Bishop评分(OR=0.122,95%CI=0.010~1.441)、既往阴道分娩史(OR=0.034,95%CI=1.297~715.194)、早产(OR=186.54,95%CI=2.225~15638.578)及自然临产(OR=52.37,95%CI=8.949~306.517)均是VBAC的影响因素。结论:VBAC的影响因素为孕妇的孕周、既往阴道分娩分娩史、既往因不良孕产史引产、存在妊娠合并症、入院时宫颈Bishop评分、自然临产、早产史。VBAC组产后24 h出血量低于TOLAC失败组。
