Implantable cervical vagus nerve stimulation(i VNS) is a representative and promising neuromodulation.However,the invasive nature restricts its application.Traditional auricular acupuncture treatment has a long histor...Implantable cervical vagus nerve stimulation(i VNS) is a representative and promising neuromodulation.However,the invasive nature restricts its application.Traditional auricular acupuncture treatment has a long history.The auricular branch of the vagus nerve(ABVN) is a branch on the surface of the ear.Some studies demonstrates that transcutaneous auricular vagus nerve stimulation(ta VNS) would achieve similar effects as i VNS.Ta VNS and i VNS share a common anatomical basis and acting mechanism.In this article,we made a comparison between i VNS and ta VNS in indications and efficacy.The recent studies have revealed similar clinical efficacy of ta VNS,ta VNS would expand the indication of i VNS.Highquality clinical evidences are needed before ta VNS become be an alternative of i VNS.展开更多
目的:评价在腹腔镜远端胃癌根治术中实施迷走神经肝支保护以降低术后胆囊结石发生率的作用。方法:选取81例胃癌患者进行前瞻性研究,随机分为迷走神经保护组(研究组)与非迷走神经保护组(对照组),行腹腔镜胃癌根治术加迷走神经保护或单纯...目的:评价在腹腔镜远端胃癌根治术中实施迷走神经肝支保护以降低术后胆囊结石发生率的作用。方法:选取81例胃癌患者进行前瞻性研究,随机分为迷走神经保护组(研究组)与非迷走神经保护组(对照组),行腹腔镜胃癌根治术加迷走神经保护或单纯腹腔镜胃癌根治术。观察两组术中出血量、手术时间、术后淋巴结清扫数量、术后并发症等指标,并随访两年,了解是否发生胆囊结石。结果:两组术中出血量[(91.3±42.8) mL vs.(108.5±54.9) mL,P=0.151]、手术时间[(202.1±48.6) min vs.(184.5±54.1) min,P=0.175]、淋巴结清扫数量[(22.7±10.1) vs.(22.3±9.26),P=0.885]、术后并发症发生率(8.20%vs. 15%,P=0.379)差异无统计学意义。术后胆囊结石发生率研究组低于对照组(4.92%vs. 20%,P=0.038)。结论:腹腔镜下迷走神经肝支保护是安全的,可保证手术的根治程度,同时降低术后胆囊结石发生率。展开更多
基金Supported by the China Academy of Chinese Medical Sciences Innovation Fund:Brain Effects and Multimodal Imaging Mechanism of Transcutaneous Auricular Vagus Nerve Stimulation in Patients with Disorder of Consciousness(CI2021A03305)the National Key Research and Development Program:Optimization and Effect Mechanism of Transcutaneous Electrical Cranial-auricular Acupoint Stimulation(TECAS) on Depression(No.2018YFC1705800)。
文摘Implantable cervical vagus nerve stimulation(i VNS) is a representative and promising neuromodulation.However,the invasive nature restricts its application.Traditional auricular acupuncture treatment has a long history.The auricular branch of the vagus nerve(ABVN) is a branch on the surface of the ear.Some studies demonstrates that transcutaneous auricular vagus nerve stimulation(ta VNS) would achieve similar effects as i VNS.Ta VNS and i VNS share a common anatomical basis and acting mechanism.In this article,we made a comparison between i VNS and ta VNS in indications and efficacy.The recent studies have revealed similar clinical efficacy of ta VNS,ta VNS would expand the indication of i VNS.Highquality clinical evidences are needed before ta VNS become be an alternative of i VNS.
文摘目的:评价在腹腔镜远端胃癌根治术中实施迷走神经肝支保护以降低术后胆囊结石发生率的作用。方法:选取81例胃癌患者进行前瞻性研究,随机分为迷走神经保护组(研究组)与非迷走神经保护组(对照组),行腹腔镜胃癌根治术加迷走神经保护或单纯腹腔镜胃癌根治术。观察两组术中出血量、手术时间、术后淋巴结清扫数量、术后并发症等指标,并随访两年,了解是否发生胆囊结石。结果:两组术中出血量[(91.3±42.8) mL vs.(108.5±54.9) mL,P=0.151]、手术时间[(202.1±48.6) min vs.(184.5±54.1) min,P=0.175]、淋巴结清扫数量[(22.7±10.1) vs.(22.3±9.26),P=0.885]、术后并发症发生率(8.20%vs. 15%,P=0.379)差异无统计学意义。术后胆囊结石发生率研究组低于对照组(4.92%vs. 20%,P=0.038)。结论:腹腔镜下迷走神经肝支保护是安全的,可保证手术的根治程度,同时降低术后胆囊结石发生率。