The paper investigates the h-p version of the infinite element method. An exponential conver gence can be abtained by a small amount of computing work.
Oscar Wilde was one of the most successful playwrights of the late Victorian era in London.De Profundis is a collection of letters written by him while he was imprisoned after being convicted of "gross indecency&...Oscar Wilde was one of the most successful playwrights of the late Victorian era in London.De Profundis is a collection of letters written by him while he was imprisoned after being convicted of "gross indecency" with other men.The language in it is colloquial yet still retains the distinguishing features of Wilde's work,which is full of the flowers of speech and sparkling of ideas.The two Chinese versions of the book exhibit exquisite techniques of the translators and their different ways of dealing with the various problems of translation.This article is going to do a comparative work between the two versions.In chapter 3,there will be a detailed analysis of the two versions from different aspects to see how the two translators reproduce the grammatical and functional meaning of the source language while still retaining the original style.展开更多
Contents1. Diagnosis and dynamic assessment of persistent/recurrent and metastatic differentiated thyroid cancer (prmDTC)1.1 Basic principles of diagnosis1.2 Diagnostic methods1.3 Ongoing assessment of response to the...Contents1. Diagnosis and dynamic assessment of persistent/recurrent and metastatic differentiated thyroid cancer (prmDTC)1.1 Basic principles of diagnosis1.2 Diagnostic methods1.3 Ongoing assessment of response to therapy2. Multidisciplinary treatment of prmDTC2.1 Basic principles of treatment2.2 Surgical management2.2.1 Preoperative clinical assessment2.2.2 Principles of surgical treatment for prmDTC.展开更多
This paper explores the relationship between the original and its translation by interpreting Benjamin's three metaphors from his The Translator's Task. The exploration starts with the metaphor of"the tan...This paper explores the relationship between the original and its translation by interpreting Benjamin's three metaphors from his The Translator's Task. The exploration starts with the metaphor of"the tangent of a circle",where it is interpreted that although the translated version should be faithful to its original in terms of meaning,yet it is a deviation due to different internal and external factors. Then,in the metaphor of"afterlife",the discussion demonstrates that the translated version proceeds from the original,but the original depends on it for its survival and afterlife in different eras. Later,based on the metaphor of"fragments of a vessel",the author states that the original and its translation are equal and complementary,just like the fragments of a vessel,responsible for the development and renewal of each other through translation. Finally,it is concluded that a better understanding of their relationship can offer us a new perspective in translation studies and practice.展开更多
Objective: Response Evaluation Criteria in Solid Tumors (RECIST) guideline version 1.0 (RECIST 1.0) was proposed as a new guideline for evaluating tumor response and has been widely accepted as a standardized mea...Objective: Response Evaluation Criteria in Solid Tumors (RECIST) guideline version 1.0 (RECIST 1.0) was proposed as a new guideline for evaluating tumor response and has been widely accepted as a standardized measure. With a number of issues being raised on RECIST 1.0, however, a revised RECIST guideline version 1.1 (RECIST 1.1) was proposed by the RECIST Working Group in 2009. This study was conducted to compare CT tumor response based on RECIST 1.1 vs. RECIST 1.0 in patients with advanced gastric cancer (AGC). Methods: We reviewed 61 AGC patients with measurable diseases by RECIST 1.0 who were enrolled in other clinical trials between 2008 and 2010. These patients were retrospectively re-analyzed to determine the concordance between the two response criteria using the κ statistic. Results: The number and sum of tumor diameters of the target lesions by RECIST 1.1 were significantly lower than those by RECIST 1.0 (P〈0.0001). However, there was excellent agreement in tumor response between RECIST 1.1 and RECIST 1.0 0(κ=0.844). The overall response rates (ORRs) according to RECIST 1.0 and RECIST 1.1 were 32.7% (20/61) and 34.5% (20/58), respectively. One patient with partial response (PR) based on RECIST 1.0 was reclassified as stable disease (SD) by RECIST 1.1. Of two patients with SD by RECIST 1.0, one was downgraded to progressive disease and the other was upgraded to PR by RECIST 1.1. Conclusions: RECIST 1.1 provided almost perfect agreement with RECIST 1.0 in the CT assessment of tumor response of AGC.展开更多
Contents1. Overview2. Risk factors of prostate cancer2.1 Age and genetic factors2.2 Exogenous factors3. Pathological classification and grading system4. Diagnostic evaluation4.1 Monitoring and screening for population...Contents1. Overview2. Risk factors of prostate cancer2.1 Age and genetic factors2.2 Exogenous factors3. Pathological classification and grading system4. Diagnostic evaluation4.1 Monitoring and screening for population with high-risk prostate cancer4.2 Genetic testing4.3 Digital rectal examination (DRE)4.4 Magnetic resonance examination4.5 Bone scan examination.展开更多
AIM: To investigate the Chinese version of the Low Vision Quality of Life Questionnaire(CLVQOL) as an instrument for obtaining clinically important changes after cataract surgery.METHODS: Patients underwent cataract s...AIM: To investigate the Chinese version of the Low Vision Quality of Life Questionnaire(CLVQOL) as an instrument for obtaining clinically important changes after cataract surgery.METHODS: Patients underwent cataract surgery in Shanghai General Hospital, Shanghai Jiao Tong University, who fit the inclusion criteria were recruited. Two CLVQOLs were administered, including a preoperative CLVQOL and a CLVQOL at the end of the 3 mo follow-up period, and were completed using face-to-face interviews or phone interviews conducted by trained investigators. The minimal clinically important difference(MCID) was calculated using an anchor-based method and a distribution method. In addition, the responsiveness of the questionnaire was measured.RESULTS: A total of 155 residents were enrolled. The average visual acuity(VA) preoperatively was 0.08(SD=0.05), and it increased to 0.47(SD=0.28) at the end of followup. Statistically significant positive changes in the CLVQOL scores indicated significant improvement of vision related quality of life after cataract surgery. With the larger value between the two results as the final value, the MCID values of the CLVQOL(scores of the four scales as well as the total score) were 8.94, 2.61, 4.34, 3.10 and 17.63, respectively. The CLVQOL has both good internal and external responsiveness.CONCLUSION: CLVQOL scores are appropriate instruments for obtaining clinically important changes after cataract surgery. This study is an effective exploration for establishingcataract surgery efficacy standards, which helps clinical and scientific research workers in ophthalmology to gain a more in-depth understanding when using CLVQOL.展开更多
Background: Laparoscopic hepatectomy has many advantages over open surgery, including minimiza- tion of local injury, reduced systemic reactions, and faster postoperative recovery. The aim of this "Consensus" is to...Background: Laparoscopic hepatectomy has many advantages over open surgery, including minimiza- tion of local injury, reduced systemic reactions, and faster postoperative recovery. The aim of this "Consensus" is to provide guidance and reference to surgeons who perform, or are interested in per- forming laparoscopic liver surgeries. Methods: The National Hepatic Surgery Group of the Society of Surgery, a professional society of the Chinese Medical Association, gathered 60 expert hepatic surgeons in Wuhan, China in December 2012, and an "Expert Consensus on Laparoseopic Hepatectomy" was developed. Results: The types of hepatectomy, indications and contraindications, preoperative preparation, anes- thesia, patient position, insuffiation pressure, port position, control of hepatic inflow and outflow, indi- cations for conversion to open surgery, and surgical devices and equipment are reviewed. Techniques and procedures of various laparoscopic hepatectomies are also discussed.展开更多
Professionalism is crucial in all professions and is particularly important in the medical field.Measuring students' perceptions of professionalism can help to form education targeting the enhancement of professio...Professionalism is crucial in all professions and is particularly important in the medical field.Measuring students' perceptions of professionalism can help to form education targeting the enhancement of professionalism.This study aimed to validate an effective assessment tool for the measurement of medical students5 perceptions of medical professionalism in China's Mainland.The cross-sectional survey was conducted in three medical colleges in Guangdong,China.Of the 2103 eligible medical students,1976 responded,and 1856 questionnaires were deemed valid.Students from clinical medicine in these three medical colleges were randomly selected by cluster sampling.First,a Simplified Chinese Version questionnaire to measure Student's Perception of Medical Professionalism (SCV-SPMP) was constructed.Second,questionnaires from 1856 students majoring in clinical medicine at three medical colleges were included in the analysis.Third,exploratory factor analysis,Cronbach's alpha,item-subscale correlation,and confirmatory factor analysis were conducted to test the validity and reliability of the SCV-SPMP.Nine items were eliminated following exploratory factor analysis,and four subscales were extracted from the analysis.All internal consistency reliability exceeded the minimum standard.The overall Cronbach's alpha was 0.94,and four subscales' alphas were 0.82 (Accountability and excellence),0.81 (Duty),0.89 (Honor and integrity),and 0.85 (Practice habits and respect for others),respectively.The model fit was good.The convergent validity and discriminant validity were acceptable.The modified SCVSPMP was found to be a valid and reliable tool to capture the main features of Chinese students' perceptions of medical professionalism in four dimensions,and it provides a quantitative method for the measurement of the students' perceptions in China's Mainland..展开更多
Pipe cooling is an effective method of mass concrete temperature control, but its accurate and convenient numerical simulation is still a cumbersome problem. An improved embedded model, considering the water temperatu...Pipe cooling is an effective method of mass concrete temperature control, but its accurate and convenient numerical simulation is still a cumbersome problem. An improved embedded model, considering the water temperature variation along the pipe, was proposed for simulating the temperature field of early-age concrete structures containing cooling pipes. The improved model was verified with an engineering example. Then, the p-version self-adaption algorithm for the improved embedded model was deduced, and the initial values and boundary conditions were examined. Comparison of some numerical samples shows that the proposed model can provide satisfying precision and a higher efficiency. The analysis efficiency can be doubled at the same precision, even for a large-scale element. The p-version algorithm can fit grids of different sizes for the temperature field simulation. The convenience of the proposed algorithm lies in the possibility of locating more pipe segments in one element without the need of so regular a shape as in the explicit model.展开更多
A novel dynamic batch selective sampling algorithm based on version space analysis is presented. In the traditional batch selective sampling, example selection is entirely determined by the existing unreliable classif...A novel dynamic batch selective sampling algorithm based on version space analysis is presented. In the traditional batch selective sampling, example selection is entirely determined by the existing unreliable classification boundary; meanwhile, within a batch, examples labeled previously fail to provide instructive information for the selection of the rest. As a result, using the examples selected in batch mode for model refinement will jeopardize the classification performance. Based on the duality between feature space and parameter space under the SVM active learning fi:amework, dynamic batch selective sampling is proposed to address the problem. We select a batch of examples dynamically, using the examples labeled previously as guidance for further selection. In this way, the selection of feedback examples is determined by both the existing classification model and the examples labeled previously. Encouraging experimental results demonstrate the effectiveness of the proposed algorithm.展开更多
Based on the key function of version management in PDM system, this paper discusses the function and the realization of version management and the transitions of version states with a workflow. A directed aeyclic grap...Based on the key function of version management in PDM system, this paper discusses the function and the realization of version management and the transitions of version states with a workflow. A directed aeyclic graph is used to describe a version model. Three storage modes of the directed acyelic graph version model in the database, the bumping block and the PDM working memory are presented and the conversion principle of these three modes is given. The study indicates that building a dynamic product structure configuration model based on versions is the key to resolve the problem. Thus a version model of single product object is built. Then the version management model in product structure configuration is built and the application of version management of PDM syster is presented as a case.展开更多
Introduction: This study aimed to develop valid and reliable scale with the intention of measure Coping Self-efficacy (CSES) of Iranian type 2 diabetic patients. Patients and Methods: Validity and reliability of Irani...Introduction: This study aimed to develop valid and reliable scale with the intention of measure Coping Self-efficacy (CSES) of Iranian type 2 diabetic patients. Patients and Methods: Validity and reliability of Iranian version of Coping Self-efficacy Scale (CSES) were measured by a cross-sectional study. Content validity, reliability and cultural equivalency were appraised through qualitative and quantitative study on 260 participants who have type 2 diabetes. Results: Reliability and validity of the scale and its four subscales, such as “stop unpleasant emotions and thoughts” (a = 0.92) “used problem-focused coping” (a = 0.71), Self-efficacy on diabetes problem solving (a = 0.74) and “get support from friends and family” (a = 0.67) were approved explicitly by a psychometric analysis;these show that the scale was slightly valid and reliable on the study setting. An intraclass correlation coefficient was satisfactory (p < 0.001). Criterion validity between total scale and metabolic control Index (HbA1c) of type 2 diabetic patients was significant (p < 0.001) and showed indirect correlation with the domains of the scale. Conclusion: Study findings supported the reliability and validity of the Iranian version of new Coping Self-efficacy-24 for measuring Coping Selfefficacy among Iranian type 2 diabetic patients. Based on our finding, we would like to recommend appropriate interventions in the future.展开更多
Waxy maize is a specialty maize that produces mainly amylopectin starch with special food or industrial values. The objective of this study was to overcome the limitations of wx mutant allele acquisition and breeding ...Waxy maize is a specialty maize that produces mainly amylopectin starch with special food or industrial values. The objective of this study was to overcome the limitations of wx mutant allele acquisition and breeding efficiency by conversion of parental lines from normal to waxy maize. The intended mutation activity was achieved by in vivo CRISPR/Cas9 machinery involving desired-target mutation of the Wx locus in the ZC01 background,abbreviated as ZC01-DTM^(wx). Triple selection was applied to segregants to obtain high genome background recovery with transgene-free wx mutations. The targeted mutation was identified, yielding six types of mutations among progeny crossed with ZC01-DTM^(wx).The amylopectin contents of the endosperm starch in mutant lines and hybrids averaged94.9%, while those of the wild-type controls were significantly(P < 0.01) lower, with an average of 76.9%. Double selection in transgene-free lines was applied using the Bar strip test and Cas9 PCR screening. The genome background recovery ratios of the lines were determined using genome-wide SNP data. That of lines used as male parents was as high as98.19% and that of lines used as female parents was as high as 86.78%. Conversion hybrids and both parental lines showed agronomic performance similar to that of their wild-type counterparts. This study provides a practical example of the efficient extension of CRISPR/Cas9 targeted mutation to industrial hybrids for transformation of a recalcitrant species.展开更多
This paper deals with the exact detection analysis of the Ordered-Statistic(OS) processor along with OS Greatest Of(OSGO) and OS Smallest Of(OSSO) modified versions, for M postdetection integrated pulses when the oper...This paper deals with the exact detection analysis of the Ordered-Statistic(OS) processor along with OS Greatest Of(OSGO) and OS Smallest Of(OSSO) modified versions, for M postdetection integrated pulses when the operating environment is nonhomogeneous. Analytical results are presented in multiple-target case as well as in regions of clutter power transitions. The primary and the secondary interfering targets are assumed to be fluctuating in accordance with the SWII target fluctuation model. As the number of noncoherently integrated pulses increases,lower threshold values and consequently better detection performances are obtained in both homogeneous and multiple target background models. However, the false alarm rate performance of OSSO-CFAR(Constant False Alarm Rate) scheme at clutter edges is worsen with increasing the postdetection integrated pulses. As predicted, the OSGO-CFAR detector accommodates the presence of spurious targets in the reference window, given that their number is within its allowable range in each local window, and controls the rate of false alarm when the contents of the reference cells have clutter boundaries.展开更多
基金The research was supported by the Doctoral Program Foundation of Chinese UniversitiesNational Natural Science Foundation of China (19771021)
文摘The paper investigates the h-p version of the infinite element method. An exponential conver gence can be abtained by a small amount of computing work.
文摘Oscar Wilde was one of the most successful playwrights of the late Victorian era in London.De Profundis is a collection of letters written by him while he was imprisoned after being convicted of "gross indecency" with other men.The language in it is colloquial yet still retains the distinguishing features of Wilde's work,which is full of the flowers of speech and sparkling of ideas.The two Chinese versions of the book exhibit exquisite techniques of the translators and their different ways of dealing with the various problems of translation.This article is going to do a comparative work between the two versions.In chapter 3,there will be a detailed analysis of the two versions from different aspects to see how the two translators reproduce the grammatical and functional meaning of the source language while still retaining the original style.
文摘Contents1. Diagnosis and dynamic assessment of persistent/recurrent and metastatic differentiated thyroid cancer (prmDTC)1.1 Basic principles of diagnosis1.2 Diagnostic methods1.3 Ongoing assessment of response to therapy2. Multidisciplinary treatment of prmDTC2.1 Basic principles of treatment2.2 Surgical management2.2.1 Preoperative clinical assessment2.2.2 Principles of surgical treatment for prmDTC.
文摘This paper explores the relationship between the original and its translation by interpreting Benjamin's three metaphors from his The Translator's Task. The exploration starts with the metaphor of"the tangent of a circle",where it is interpreted that although the translated version should be faithful to its original in terms of meaning,yet it is a deviation due to different internal and external factors. Then,in the metaphor of"afterlife",the discussion demonstrates that the translated version proceeds from the original,but the original depends on it for its survival and afterlife in different eras. Later,based on the metaphor of"fragments of a vessel",the author states that the original and its translation are equal and complementary,just like the fragments of a vessel,responsible for the development and renewal of each other through translation. Finally,it is concluded that a better understanding of their relationship can offer us a new perspective in translation studies and practice.
文摘Objective: Response Evaluation Criteria in Solid Tumors (RECIST) guideline version 1.0 (RECIST 1.0) was proposed as a new guideline for evaluating tumor response and has been widely accepted as a standardized measure. With a number of issues being raised on RECIST 1.0, however, a revised RECIST guideline version 1.1 (RECIST 1.1) was proposed by the RECIST Working Group in 2009. This study was conducted to compare CT tumor response based on RECIST 1.1 vs. RECIST 1.0 in patients with advanced gastric cancer (AGC). Methods: We reviewed 61 AGC patients with measurable diseases by RECIST 1.0 who were enrolled in other clinical trials between 2008 and 2010. These patients were retrospectively re-analyzed to determine the concordance between the two response criteria using the κ statistic. Results: The number and sum of tumor diameters of the target lesions by RECIST 1.1 were significantly lower than those by RECIST 1.0 (P〈0.0001). However, there was excellent agreement in tumor response between RECIST 1.1 and RECIST 1.0 0(κ=0.844). The overall response rates (ORRs) according to RECIST 1.0 and RECIST 1.1 were 32.7% (20/61) and 34.5% (20/58), respectively. One patient with partial response (PR) based on RECIST 1.0 was reclassified as stable disease (SD) by RECIST 1.1. Of two patients with SD by RECIST 1.0, one was downgraded to progressive disease and the other was upgraded to PR by RECIST 1.1. Conclusions: RECIST 1.1 provided almost perfect agreement with RECIST 1.0 in the CT assessment of tumor response of AGC.
文摘Contents1. Overview2. Risk factors of prostate cancer2.1 Age and genetic factors2.2 Exogenous factors3. Pathological classification and grading system4. Diagnostic evaluation4.1 Monitoring and screening for population with high-risk prostate cancer4.2 Genetic testing4.3 Digital rectal examination (DRE)4.4 Magnetic resonance examination4.5 Bone scan examination.
文摘AIM: To investigate the Chinese version of the Low Vision Quality of Life Questionnaire(CLVQOL) as an instrument for obtaining clinically important changes after cataract surgery.METHODS: Patients underwent cataract surgery in Shanghai General Hospital, Shanghai Jiao Tong University, who fit the inclusion criteria were recruited. Two CLVQOLs were administered, including a preoperative CLVQOL and a CLVQOL at the end of the 3 mo follow-up period, and were completed using face-to-face interviews or phone interviews conducted by trained investigators. The minimal clinically important difference(MCID) was calculated using an anchor-based method and a distribution method. In addition, the responsiveness of the questionnaire was measured.RESULTS: A total of 155 residents were enrolled. The average visual acuity(VA) preoperatively was 0.08(SD=0.05), and it increased to 0.47(SD=0.28) at the end of followup. Statistically significant positive changes in the CLVQOL scores indicated significant improvement of vision related quality of life after cataract surgery. With the larger value between the two results as the final value, the MCID values of the CLVQOL(scores of the four scales as well as the total score) were 8.94, 2.61, 4.34, 3.10 and 17.63, respectively. The CLVQOL has both good internal and external responsiveness.CONCLUSION: CLVQOL scores are appropriate instruments for obtaining clinically important changes after cataract surgery. This study is an effective exploration for establishingcataract surgery efficacy standards, which helps clinical and scientific research workers in ophthalmology to gain a more in-depth understanding when using CLVQOL.
文摘Background: Laparoscopic hepatectomy has many advantages over open surgery, including minimiza- tion of local injury, reduced systemic reactions, and faster postoperative recovery. The aim of this "Consensus" is to provide guidance and reference to surgeons who perform, or are interested in per- forming laparoscopic liver surgeries. Methods: The National Hepatic Surgery Group of the Society of Surgery, a professional society of the Chinese Medical Association, gathered 60 expert hepatic surgeons in Wuhan, China in December 2012, and an "Expert Consensus on Laparoseopic Hepatectomy" was developed. Results: The types of hepatectomy, indications and contraindications, preoperative preparation, anes- thesia, patient position, insuffiation pressure, port position, control of hepatic inflow and outflow, indi- cations for conversion to open surgery, and surgical devices and equipment are reviewed. Techniques and procedures of various laparoscopic hepatectomies are also discussed.
文摘Professionalism is crucial in all professions and is particularly important in the medical field.Measuring students' perceptions of professionalism can help to form education targeting the enhancement of professionalism.This study aimed to validate an effective assessment tool for the measurement of medical students5 perceptions of medical professionalism in China's Mainland.The cross-sectional survey was conducted in three medical colleges in Guangdong,China.Of the 2103 eligible medical students,1976 responded,and 1856 questionnaires were deemed valid.Students from clinical medicine in these three medical colleges were randomly selected by cluster sampling.First,a Simplified Chinese Version questionnaire to measure Student's Perception of Medical Professionalism (SCV-SPMP) was constructed.Second,questionnaires from 1856 students majoring in clinical medicine at three medical colleges were included in the analysis.Third,exploratory factor analysis,Cronbach's alpha,item-subscale correlation,and confirmatory factor analysis were conducted to test the validity and reliability of the SCV-SPMP.Nine items were eliminated following exploratory factor analysis,and four subscales were extracted from the analysis.All internal consistency reliability exceeded the minimum standard.The overall Cronbach's alpha was 0.94,and four subscales' alphas were 0.82 (Accountability and excellence),0.81 (Duty),0.89 (Honor and integrity),and 0.85 (Practice habits and respect for others),respectively.The model fit was good.The convergent validity and discriminant validity were acceptable.The modified SCVSPMP was found to be a valid and reliable tool to capture the main features of Chinese students' perceptions of medical professionalism in four dimensions,and it provides a quantitative method for the measurement of the students' perceptions in China's Mainland..
基金supported by the National Natural Science Foundation of China(Grant No.51109071)
文摘Pipe cooling is an effective method of mass concrete temperature control, but its accurate and convenient numerical simulation is still a cumbersome problem. An improved embedded model, considering the water temperature variation along the pipe, was proposed for simulating the temperature field of early-age concrete structures containing cooling pipes. The improved model was verified with an engineering example. Then, the p-version self-adaption algorithm for the improved embedded model was deduced, and the initial values and boundary conditions were examined. Comparison of some numerical samples shows that the proposed model can provide satisfying precision and a higher efficiency. The analysis efficiency can be doubled at the same precision, even for a large-scale element. The p-version algorithm can fit grids of different sizes for the temperature field simulation. The convenience of the proposed algorithm lies in the possibility of locating more pipe segments in one element without the need of so regular a shape as in the explicit model.
文摘A novel dynamic batch selective sampling algorithm based on version space analysis is presented. In the traditional batch selective sampling, example selection is entirely determined by the existing unreliable classification boundary; meanwhile, within a batch, examples labeled previously fail to provide instructive information for the selection of the rest. As a result, using the examples selected in batch mode for model refinement will jeopardize the classification performance. Based on the duality between feature space and parameter space under the SVM active learning fi:amework, dynamic batch selective sampling is proposed to address the problem. We select a batch of examples dynamically, using the examples labeled previously as guidance for further selection. In this way, the selection of feedback examples is determined by both the existing classification model and the examples labeled previously. Encouraging experimental results demonstrate the effectiveness of the proposed algorithm.
基金the Scientific Technology Development Project of Heilongjiang(Grant No.WH05A01 and GB05A103)Scientific Technology Development Project of Harbin
文摘Based on the key function of version management in PDM system, this paper discusses the function and the realization of version management and the transitions of version states with a workflow. A directed aeyclic graph is used to describe a version model. Three storage modes of the directed acyelic graph version model in the database, the bumping block and the PDM working memory are presented and the conversion principle of these three modes is given. The study indicates that building a dynamic product structure configuration model based on versions is the key to resolve the problem. Thus a version model of single product object is built. Then the version management model in product structure configuration is built and the application of version management of PDM syster is presented as a case.
文摘Introduction: This study aimed to develop valid and reliable scale with the intention of measure Coping Self-efficacy (CSES) of Iranian type 2 diabetic patients. Patients and Methods: Validity and reliability of Iranian version of Coping Self-efficacy Scale (CSES) were measured by a cross-sectional study. Content validity, reliability and cultural equivalency were appraised through qualitative and quantitative study on 260 participants who have type 2 diabetes. Results: Reliability and validity of the scale and its four subscales, such as “stop unpleasant emotions and thoughts” (a = 0.92) “used problem-focused coping” (a = 0.71), Self-efficacy on diabetes problem solving (a = 0.74) and “get support from friends and family” (a = 0.67) were approved explicitly by a psychometric analysis;these show that the scale was slightly valid and reliable on the study setting. An intraclass correlation coefficient was satisfactory (p < 0.001). Criterion validity between total scale and metabolic control Index (HbA1c) of type 2 diabetic patients was significant (p < 0.001) and showed indirect correlation with the domains of the scale. Conclusion: Study findings supported the reliability and validity of the Iranian version of new Coping Self-efficacy-24 for measuring Coping Selfefficacy among Iranian type 2 diabetic patients. Based on our finding, we would like to recommend appropriate interventions in the future.
基金supported the National Transgenic Science and Technology Program(2019ZX08010-003)the National Natural Science Foundation of China(31771808)+3 种基金the National Key Research and Development Program of China(2016YFD0101803)the Key Area Research and Development Program of Guangdong Province(2018B020202008)Beijing Municipal Science and Technology Commission(D171100007717001)National Engineering Laboratory for Crop Molecular Breeding。
文摘Waxy maize is a specialty maize that produces mainly amylopectin starch with special food or industrial values. The objective of this study was to overcome the limitations of wx mutant allele acquisition and breeding efficiency by conversion of parental lines from normal to waxy maize. The intended mutation activity was achieved by in vivo CRISPR/Cas9 machinery involving desired-target mutation of the Wx locus in the ZC01 background,abbreviated as ZC01-DTM^(wx). Triple selection was applied to segregants to obtain high genome background recovery with transgene-free wx mutations. The targeted mutation was identified, yielding six types of mutations among progeny crossed with ZC01-DTM^(wx).The amylopectin contents of the endosperm starch in mutant lines and hybrids averaged94.9%, while those of the wild-type controls were significantly(P < 0.01) lower, with an average of 76.9%. Double selection in transgene-free lines was applied using the Bar strip test and Cas9 PCR screening. The genome background recovery ratios of the lines were determined using genome-wide SNP data. That of lines used as male parents was as high as98.19% and that of lines used as female parents was as high as 86.78%. Conversion hybrids and both parental lines showed agronomic performance similar to that of their wild-type counterparts. This study provides a practical example of the efficient extension of CRISPR/Cas9 targeted mutation to industrial hybrids for transformation of a recalcitrant species.
文摘This paper deals with the exact detection analysis of the Ordered-Statistic(OS) processor along with OS Greatest Of(OSGO) and OS Smallest Of(OSSO) modified versions, for M postdetection integrated pulses when the operating environment is nonhomogeneous. Analytical results are presented in multiple-target case as well as in regions of clutter power transitions. The primary and the secondary interfering targets are assumed to be fluctuating in accordance with the SWII target fluctuation model. As the number of noncoherently integrated pulses increases,lower threshold values and consequently better detection performances are obtained in both homogeneous and multiple target background models. However, the false alarm rate performance of OSSO-CFAR(Constant False Alarm Rate) scheme at clutter edges is worsen with increasing the postdetection integrated pulses. As predicted, the OSGO-CFAR detector accommodates the presence of spurious targets in the reference window, given that their number is within its allowable range in each local window, and controls the rate of false alarm when the contents of the reference cells have clutter boundaries.