四川西部地区地理环境复杂,滑坡空间结构多样且变形剧烈。为有效预防滑坡灾害,需要探究相关区域滑坡危险性可靠评价方法。利用G1-熵权耦合赋权逼近理想解排序法(technique for order preference by similarity to ideal solution,TOPSIS...四川西部地区地理环境复杂,滑坡空间结构多样且变形剧烈。为有效预防滑坡灾害,需要探究相关区域滑坡危险性可靠评价方法。利用G1-熵权耦合赋权逼近理想解排序法(technique for order preference by similarity to ideal solution,TOPSIS)构建滑坡灾害危险性评价模型,选取高程、降雨、地震动参数等12个评价因子,对雅砻江滑坡灾害危险性进行评价。依据贴近度将滑坡区域分为4个等级,即高危险区(0.75~1)、较高危险区(0.5~0.75)、中等危险区(0.25~0.5)和低危险区(0~0.25)。同时,对比了由差分干涉测量短基线集时序分析(small baseline subset interferometric synthetic aperture radar,SBAS-InSAR)技术得到的4个区域滑坡实测结果和本文评价模型的分析结果。利用G1-熵权耦合赋权TOPSIS得到九龙县烟袋镇桤木林村高生地滑坡、新龙县和平乡甲西村麻西滑坡、德格县年古乡政府滑坡和甘孜县扎科乡达玛滑坡的贴近度分别为0.854、0.686、0.405和0.224,由SBAS-InSAR技术得到滑坡前缘局部变形速率分别为-150、-43、-66、30 mm/a,二者之间有显著的对应关系,证明本文评价模型的准确性。应用G1-熵权耦合赋权TOPSIS法对滑坡危险性评价具有较高的准确性,该方法可为其他地区滑坡地质灾害评价提供参考。展开更多
Background: Studies have shown a strong correlation between the growth of E2 in serum and estrone-3-glucuronide (E1-3G) in urine during ovarian stimulation. Thus, we developed theoretical models for using urinary E1-3...Background: Studies have shown a strong correlation between the growth of E2 in serum and estrone-3-glucuronide (E1-3G) in urine during ovarian stimulation. Thus, we developed theoretical models for using urinary E1-3G in ovarian stimulation and focused on their experimental verification and analysis. Methods: A prospective, observational pilot study was conducted involving 54 patients who underwent 54 cycles of ovarian stimulation. The goal was to establish the growth rate of urinary E1-3G during the course of stimulation and to determine the daily upper and lower limits of growth rates at which stimulation is appropriate and safe. Controlled ovarian stimulation was performed using two different stimulation protocols—an antagonist protocol in 25 cases and a progestin-primed ovarian stimulation protocol (PPOS) in 29 cases, with fixed doses of gonadotropins. From the second day of stimulation, patients self-measured their daily urine E1-3G levels at home using a portable analyzer. In parallel, a standard ultrasound follow-up protocol accompanied by a determination of E2, LH, and P levels was applied to optimally control stimulation. Results: The average daily growth rates in both groups were about 50%. The daily increase in E1-3G for the antagonist protocol ranged from 14% to 79%, while they were 28% to 79% for the PPOS protocol. Conclusion: This is the first study to analyze the dynamics of E1-3G in two different protocols and to estimate the limits of its increase during the entire course of the stimulation. The results confirm our theoretical model for the viability of using urinary E1-3G for monitoring ovarian stimulation.展开更多
文摘四川西部地区地理环境复杂,滑坡空间结构多样且变形剧烈。为有效预防滑坡灾害,需要探究相关区域滑坡危险性可靠评价方法。利用G1-熵权耦合赋权逼近理想解排序法(technique for order preference by similarity to ideal solution,TOPSIS)构建滑坡灾害危险性评价模型,选取高程、降雨、地震动参数等12个评价因子,对雅砻江滑坡灾害危险性进行评价。依据贴近度将滑坡区域分为4个等级,即高危险区(0.75~1)、较高危险区(0.5~0.75)、中等危险区(0.25~0.5)和低危险区(0~0.25)。同时,对比了由差分干涉测量短基线集时序分析(small baseline subset interferometric synthetic aperture radar,SBAS-InSAR)技术得到的4个区域滑坡实测结果和本文评价模型的分析结果。利用G1-熵权耦合赋权TOPSIS得到九龙县烟袋镇桤木林村高生地滑坡、新龙县和平乡甲西村麻西滑坡、德格县年古乡政府滑坡和甘孜县扎科乡达玛滑坡的贴近度分别为0.854、0.686、0.405和0.224,由SBAS-InSAR技术得到滑坡前缘局部变形速率分别为-150、-43、-66、30 mm/a,二者之间有显著的对应关系,证明本文评价模型的准确性。应用G1-熵权耦合赋权TOPSIS法对滑坡危险性评价具有较高的准确性,该方法可为其他地区滑坡地质灾害评价提供参考。
文摘Background: Studies have shown a strong correlation between the growth of E2 in serum and estrone-3-glucuronide (E1-3G) in urine during ovarian stimulation. Thus, we developed theoretical models for using urinary E1-3G in ovarian stimulation and focused on their experimental verification and analysis. Methods: A prospective, observational pilot study was conducted involving 54 patients who underwent 54 cycles of ovarian stimulation. The goal was to establish the growth rate of urinary E1-3G during the course of stimulation and to determine the daily upper and lower limits of growth rates at which stimulation is appropriate and safe. Controlled ovarian stimulation was performed using two different stimulation protocols—an antagonist protocol in 25 cases and a progestin-primed ovarian stimulation protocol (PPOS) in 29 cases, with fixed doses of gonadotropins. From the second day of stimulation, patients self-measured their daily urine E1-3G levels at home using a portable analyzer. In parallel, a standard ultrasound follow-up protocol accompanied by a determination of E2, LH, and P levels was applied to optimally control stimulation. Results: The average daily growth rates in both groups were about 50%. The daily increase in E1-3G for the antagonist protocol ranged from 14% to 79%, while they were 28% to 79% for the PPOS protocol. Conclusion: This is the first study to analyze the dynamics of E1-3G in two different protocols and to estimate the limits of its increase during the entire course of the stimulation. The results confirm our theoretical model for the viability of using urinary E1-3G for monitoring ovarian stimulation.
