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Surgical approaches for stage Ⅰ and Ⅱ thymoma-associated myasthenia gravis:feasibility of complete video-assisted thoracoscopic surgery (VATS) thymectomy in comparison with trans-sternal resection 被引量:16
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作者 Zhicheng He Quan Zhu +3 位作者 Wei Wen Liang Chen Hai Xu Hai Li 《The Journal of Biomedical Research》 CAS 2013年第1期62-70,共9页
Complete resection could be achieved in virtually all myasthenic patients with Masaoka stage I and II thymoma us- ing the trans-sternal technique. Whether this is appropriate for minimally invasive approach is not yet... Complete resection could be achieved in virtually all myasthenic patients with Masaoka stage I and II thymoma us- ing the trans-sternal technique. Whether this is appropriate for minimally invasive approach is not yet clear. We evalu- ated the feasibility of complete video-assisted thoracoscopic surgery (VATS) thymectomy for the treatment of Ma- saoka stage I and Ⅱ thymoma-associated myasthenia gravis, compared to conventional trans-sternal thymectomy. We summarized 33 patients with Masaoka stage I and II thymoma-associated myasthenia gravis between April 2006 and September 2011. Of these, 15 patients underwent right-sided complete VATS (the VATS group) by us- ing adjuvant pneuomomediastinum, comparing with 18 patients using the trans-sternal approach (the T3b group). No intraoperative death was found and no VATS case required conversion to median sternotomy. Significant differences between the two groups regarding duration of surgery and volume of intraoperative blood loss (P = 0.001 and P 〈 0.001, respectively) were observed. Postoperative morbidities were 26.7% and 33.3% for the VATS and T3b groups, respectively. All 33 patients were followed up for 12 to 61 months in the study. The cumulative probabilities of reaching complete stable remission and effective rate were 26.7% (4/15) and 93.3% (14/15) in the VATS group, which had a significantly higher complete stable remission and effective rate than those in the T3b group (P = 0.026 and P = 0.000, respectively). We conclude that VATS thymectomy utilizing adjuvant pneuomo- mediastinum for the treatment of stage I and II thymoma-associated myasthenia gravis is technically feasible but deserves further investigation in a large series with long-term follow-up. 展开更多
关键词 video-assisted thoracoscopic surgery (VATS) THYMOMA THYMECTOMY myasthenia gravis adjuvantpneuomomediastinum
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Nonintubated uniportal video-assisted thoracoscopic surgery for primary spontaneous pneumothorax 被引量:15
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作者 Shuben Li Fei Cui +5 位作者 Jun Liu Xin Xu Wenlong Shao Weiqiang Yin Hanzhang Chen Jianxing He 《Chinese Journal of Cancer Research》 SCIE CAS CSCD 2015年第2期197-202,共6页
Objective: The objective of the current study was to evaluate the feasibility and safety of nonintubated nniportal video-assisted thoracoscopic surgery (VATS) for the management of primary spontaneous pneumothorax ... Objective: The objective of the current study was to evaluate the feasibility and safety of nonintubated nniportal video-assisted thoracoscopic surgery (VATS) for the management of primary spontaneous pneumothorax (PSP). Methods: From November 2011 to June 2013, 32 consecutive patients with PSP were treated by nonintubated uniportal thoracoscopic bullectomy using epidnral anaesthesia and sedation without endotracheal intubation. An incision 2 cm in length was made at the 6th intercostal space in the median axillary line. The pleural space was entered by blunt dissection for placement of a soft incision protector. Instruments were then inserted through the incision protector to perform thoracoscopic bullectomy. Data were collected within a minimum follow-up period of 10 months. Results: The average time of surgery was 49.0 rain (range, 33-65 rain). No complications were recorded. The postoperative feeding time was 6 h. The mean postoperative chest tube drainage and hospital stay were 19.3 h and 41.6 h, respectively. The postoperative pain was mild for 30 patients (93.75%) and moderate for two patients (6.25%). No recurrences ofpneumothorax were observed at follow-up. Conclusions: The initial results indicated that nonintubated uniportal video-assisted thoracoscopic operations are not only technically feasible, but may also be a safe and less invasive alternative for select patients in the management of PSP. This is the first report to include the use of a nonintubated uniportal technique in VATS for such a large number of PSP cases. Further work and development of instruments are needed to define the applications and advantages of this technique. 展开更多
关键词 Uniportal video-assisted thoracoscopic surgery (VATS) spontaneous pneumothorax
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Safety and feasibility of video-assisted thoracoscopic surgery for stage IIIA lung cancer 被引量:12
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作者 Wenlong Shao Jun Liu +5 位作者 Wehua Liang Hanzhang Chen Shuben Li Weiqiang Yin Xin Zhang Jianxing He 《Chinese Journal of Cancer Research》 SCIE CAS CSCD 2014年第4期418-422,共5页
Objective: The current study was prospectively designed to explore the application of video-assisted thoracoscopic surgery (VATS) radical treatment for patients with stage ⅢA lung cancer, with the primary endpoint... Objective: The current study was prospectively designed to explore the application of video-assisted thoracoscopic surgery (VATS) radical treatment for patients with stage ⅢA lung cancer, with the primary endpoints being the safety and feasibility of this operation and the second endpoints being the survival and complications after the surgery. Methods: A total of 51 patients with radiologically or mediastinoscopically confirmed stage ⅢA lung cancer underwent VATS radical treatment, during which the standard pulmonary lobectomy and mediastinal lymph node dissection were performed after pre-operative assessment. The operative time, intraoperative blood loss/ complications, postoperative recovery, postoperative complications, and lymph node dissection were recorded and analyzed. This study was regarded as successful if the surgical success rate reached 90% or higher. Results: A total of 51 patients with non-small cell lung cancer (NSCLC) were enrolled in this study from March 2009 to February 2010. The median post-operative follow-up duration was 50.5 months. Of these 51 patients, 41 (80.4%) had N2 lymph node metastases. All patients underwent the thoracoscopic surgeries, among whom 50 (98%) received pulmonary lobectomy and mediastinal lymph node dissection completely under the thoracoscope, 6 had their incisions extended to about 6 cm due to larger tumor sizes, and 1 had his surgery performed using a 12 cm small incision for handling the adhesions between lymph nodes and blood vessels. No patient was converted to conventional open thoracotomy. No perioperative death was noted. One patient received a second surgery on the second post-operative day due to large drainage (〉1,000 mL), and the postoperative recovery was satisfactory. Up to 45 patients (88.2%) did not suffer from any perioperative complication, and 6 (11.8%) experienced one or more complications. Conclusions: VATS radical treatment is a safe and feasible treatment for stage ⅢA lung cancer. 展开更多
关键词 Lung cancer video-assisted thoracoscopic surgery (VATS) systematic node dissection (SND)
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A single institution experience using the LigaSure vessel sealing system in video-assisted thoracoscopic surgery for primary spontaneous pneumothorax 被引量:6
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作者 Zhi Li Liang Chen +4 位作者 Jun Wang Jianwei Qin Quan Zhu Bin Zhang Yijiang Chen 《The Journal of Biomedical Research》 CAS 2014年第6期494-497,共4页
This study sought to report our 6-year experience with the LigaSure vessel sealing system(LVSS) in videoassisted thoracoscopic surgery(VATS) for primary spontaneous pneumothorax.A series of 180 consecutive patient... This study sought to report our 6-year experience with the LigaSure vessel sealing system(LVSS) in videoassisted thoracoscopic surgery(VATS) for primary spontaneous pneumothorax.A series of 180 consecutive patients with primary spontaneous pneumothorax were operated on in our institution from May 2005 to December 2010.Intraoperatively,large lesions(bullae or blebs) with a diameter more than 2 cm were resected by staplers,and the residual lesions were treated by LVSS.LVSS was also used to ablate the apical area when no lesions were found.Conventional apical pleural abrasion was done in all cases.All patients were successfully treated using VATS with minimal perioperative bleeding.The mean operating time was 76 minutes(range,43-160 minutes) for single-side procedures and 169 minutes(range,135-195 minutes) for bilateral procedures,the mean number of applied staples was 1.93 per patient(range,0-8 days),the duration of drainage was 3.8 days(range,2-15 days),and the duration of hospital stay was 5.8 days(range,3-16 days).Postoperative complications included persistent air leak(〉 5 days) in 11 cases(6.1%) and residual pneumothorax in 6(3.3%).None required reoperation.The mean duration of follow-up was 57 months(range,24-105 months).Recurrence was seen in three cases(1.7%),and all underwent another operation thereafter.None of the lesions in the relapse cases received ablation with LVSS in the first operation.LVSS can optimize VATS for primary spontaneous pneumothorax and reduces the use of single-use staples.The method is safe,easy to use,and cost-effective and produces satisfactory results. 展开更多
关键词 LigaSure vessel sealing system video-assisted thoracoscopic surgery(VATS) primary spontaneous pneumothorax
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Middle lobe torsion after right upper and lower lobectomy:repositioning of lobar torsion using a3-cm uniportal video-assisted thoracoscopic surgery 被引量:1
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作者 Ruijie Zhang Yixin Cai +2 位作者 Shengling Fu Xiangning Fu Ni Zhang 《Oncology and Translational Medicine》 2017年第1期38-40,共3页
We aimed to describe a method for repositioning of right middle lobar torsion by using a 3-cm uniportal video-assisted thoracoscopic surgery(VATS) approach. Middle lobe torsion occurred after right upper and lower lob... We aimed to describe a method for repositioning of right middle lobar torsion by using a 3-cm uniportal video-assisted thoracoscopic surgery(VATS) approach. Middle lobe torsion occurred after right upper and lower lobectomy in a 74-year-old man. Immediate re-exploratory thoracotomy using the 3-cm uniportal VATS approach was performed. The torsion was corrected, and the lobe was anchored to the anterior chest wall with Prolene stitches. The patient recovered well postoperatively with daily improvements in chest radiographic findings. Follow-up examination was performed using fiberbronchoscopy, which revealed an unobstructed right middle lobe bronchus and sticky yellow sputum. Follow-up chest computed tomography was performed 3 months after the primary surgery and revealed increased expansion of the right middle lobe. We repositioned the right middle lobe successfully by using the 3-cm uniportal VATS approach, but more cases are needed to confirm the feasibility of the approach. Lobectomy remains the primary treatment option for such cases. 展开更多
关键词 LOBE TORSION 3-cm uniportal video-assisted thoracoscopic surgery (VATS)
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Long-term survival outcomes of video-assisted thoracic surgery for patients with non-small cell lung cancer 被引量:5
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作者 Wenlong Shao Xinguo Xiong +6 位作者 Hanzhang Chen Jun Liu Weiqiang Yin Shuben Li Xin Xu Xin Zhang Jianxing He 《Chinese Journal of Cancer Research》 SCIE CAS CSCD 2014年第4期391-398,共8页
Background: Video-assisted thoracic surgery (VATS) has been shown to be a safe alternative to conventional thoracotomy for patients with non-small cell lung cancer (NSCLC). However, popularization of this relativ... Background: Video-assisted thoracic surgery (VATS) has been shown to be a safe alternative to conventional thoracotomy for patients with non-small cell lung cancer (NSCLC). However, popularization of this relatively novel technique has been slow, partly due to concerns about its long-term outcomes. The present study aimed to evaluate the long-term survival outcomes of patients with NSCLC after VATS, and to determine the significant prognostic factors on overall survival. Methods: Consecutive patients diagnosed with NSCLC referred to one institution for VATS were identified from a central database. Patients were treated by either complete-VATS or assisted-VATS, as described in previous studies. A number of baseline patient characteristics, clinicopathologic data and treatment-related factors were analyzed as potential prognostic factors on overall survival. Results: Between January 2000 and December 2007, 1,139 patients with NSCLC who underwent VATS and fulfilled a set of predetermined inclusion criteria were included for analysis. The median age of the entire group was 60 years, with 791 male patients (69%). The median 5-year overall survival for Stage Ⅰ, Ⅱ, Ⅲ and Ⅳ disease according to the recently updated TNM classification system were 72.2%, 47.5%, 29.8% and 28.6%, respectively. Female gender, TNM stage, pT status, and type of resection were found to be significant prognostic factors on multivariate analysis. Conclusions: VATS offers a viable alternative to conventional open thoracotomy for selected patients with clinically resectableNSCLC 展开更多
关键词 Non-small cell lung cancer (NSCLC) video-assisted thoracoscopic surgery (VATS) overall survival
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Completely video-assisted thoracoscopic lobectomy versus open lobectomy for non-small cell lung cancer greater than 5 cm:a retrospective study 被引量:10
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作者 Bu Liang Li Yun +5 位作者 Yang Fan Zhao Hui Jiang Guan-chao Li Jian-feng Liu Jun Wang Jun 《Chinese Medical Journal》 SCIE CAS CSCD 2012年第3期434-439,共6页
Background Completely video-assisted thoracoscopic Iobectomy is a reasonable treatment for early-stage non-small-cell lung cancer (NSCLC).At present,the indication for this procedure is stage la and Ib peripheral lu... Background Completely video-assisted thoracoscopic Iobectomy is a reasonable treatment for early-stage non-small-cell lung cancer (NSCLC).At present,the indication for this procedure is stage la and Ib peripheral lung cancer ((〈-)5 cm); however,for larger tumors,it remains controversial whether this surgical technique is comparable to open Iobectomy.This study aimed to evaluate the safety,completeness,and efficacy of thoracoscopic Iobectomy,and to compare this technique with open Iobectomy for the treatment of non-small-cell lung cancer when the tumor's diameter was greater than 5 cm.Methods From May 2001 to April 2011,802 patients underwent a Iobectomy for treatment of non-small-cell lung cancer at our center.In 133 patients,the tumor was 〉 5 cm.There were 98 men and 35 women,median age 63 years (range:29-81 years).We divided the patients into two groups,group V (completely video-assisted thoracoscopic surgery),and group T (open Iobectomy),and evaluated the two groups for age,gender,tumor size,pathological type,location,duration of surgery,blood loss,lymph node dissection,pathological stage,time of drainage,hospitalization,complications,overall survival and recurrence.Results There were 46 cases in group V and 87 cases in group T.Age,gender,tumor size,location,pathological type and stage were similar between the two groups.Group V had shorter operative duration ((186.5±62.8) minutes vs.(256.7±67.5) minutes,P 〈0.001) and reduced bleeding ((218.5±174.6) ml vs.(556.9±187.2) ml,P 〈0.001).There were no significant differences between the two groups in complications,lymph node dissection,time of drainage and hospitalization.The recurrence between the two groups was equivalent (2.4% vs.3.8%,P=0.670).The overall survival at 1,2 and 3 years was 95.1%,81.6% and 69.6% for group V and 88.3%,78.8% and 64.0% for group T.Kaplan-Meier survival curves showed that there was no significant differences between the two groups (P=0.129).Conclusions Completely video-assisted thoracoscopic lobectomy was similar to open lobectomy in safety,completeness,and efficacy,but had a shorter operative duration,and reduced bleeding.This is a minimally invasive procedure that is feasible for a subset of non-small-cell lung cancer patients with tumor size 〉 5 cm. 展开更多
关键词 minimally invasive surgery LOBECTOMY completely video-assisted thoracoscopic lobectomy open lobectomy non-small-cell lung cancer
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Comparative study of video-assisted thoracoscopic surgery ablation and radiofrequency catheter ablation on treating paroxysmal atrial fibrillation: a randomized, controlled short-term trial 被引量:2
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作者 Wang Shizhong Liu Liqun Zou Chengwei 《Chinese Medical Journal》 SCIE CAS CSCD 2014年第14期2567-2570,共4页
Background It is unclear whether the effect of video-assisted thoracoscopic surgery ablation is better than catheter ablation on paroxysmal atrial fibrillation (PAF) or not. This study aimed to compare the effects o... Background It is unclear whether the effect of video-assisted thoracoscopic surgery ablation is better than catheter ablation on paroxysmal atrial fibrillation (PAF) or not. This study aimed to compare the effects of catheter ablation and video-assisted thoracoscopic surgery ablation on PAF. Methods From March 2008 to March 2012, 138 consecutive patients with PAF were randomly assigned to receive either video-assisted thorecoscopic surgery ablation (thoracoscopy group, n=66) or the traditional catheter ablation (catheter group, n=72). Results No patient died during the study and all were successfully followed and included in analysis. There were no significant differences in clinical and echocardiographic characteristics between the two groups. All patients were evaluated at 1 week, 1 month, 3 months, 6 months, and 12 months after discharge by physical examination and related laboratory tests. Preoperative left atrium dimensions (LADs) of the recurrent AF were (47±4) mm in the thoracoscopy group and (46±8) mm in the catheter group, whereas the LADs were (40±5) and (39±9) mm, respectively, in non-recurrent PAF. Conclusions The short-term outcome of video-assisted thoracoscopic surgery ablation is safe and effective; and the indications are wider than those for catheter ablation. The larger left atrium diameter is related to the recurrence of atrial fibrillation. Chin Med J 2014;127 (14): 2567-2570 展开更多
关键词 atrial fibrillation catheter ablation video-assisted thoracoscopic surgery ablation
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非小细胞肺癌胸腔镜与常规开胸术后血清VEGF、MMP-9变化的研究 被引量:19
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作者 田文鑫 佟宏峰 +3 位作者 孙耀光 吴青峻 马超 焦鹏 《中国肺癌杂志》 CAS 北大核心 2014年第1期24-29,共6页
背景与目的血管内皮生长因子(vascular endothelial growth factor,VEGF)及基质金属蛋白酶-9(matrix metalloproteinase-9,MMP-9)是重要的促血管生成因子,它们在肺癌血管生成中起着非常重要的作用。本研究旨在探讨非小细胞肺癌(non-smal... 背景与目的血管内皮生长因子(vascular endothelial growth factor,VEGF)及基质金属蛋白酶-9(matrix metalloproteinase-9,MMP-9)是重要的促血管生成因子,它们在肺癌血管生成中起着非常重要的作用。本研究旨在探讨非小细胞肺癌(non-small cell lung cancer,NSCLC)患者围手术期血清VEGF及MMP-9水平变化的规律,同时比较电视辅助胸腔镜手术(video-assisted thoracoscopic surgery,VATS)及常规开胸手术(traditional open surgery,TOS)后上述指标变化的差异。方法选取卫生部北京医院胸外科2010年10月-2012年8月收治的NSCLC患者43例,入组患者均在全麻下行肺叶切除、系统淋巴结清扫术,所有患者均于术前1天、术后第1、2、3、7天抽取静脉血测定血清VEGF及MMP-9的水平,观察围手术期两指标的变化规律。根据手术方式的不同将入组患者分为胸腔镜组(VATS组,25例)及常规开胸组(TOS组,18例),比较两组围手术期血清VEGF及MMP-9变化的差异。结果 NSCLC患者术后血清VEGF及MMP-9水平均呈先升高后下降的趋势,分别于术后第2天、第3天达到峰值浓度,与术前相比有明显统计学差异(P=0.031,P=0.020),术后第7天时,两者水平仍高于术前。VATS组和TOS组两组术后VEGF及MMP-9水平也均出现先升高后下降的变化规律,变化幅度以TOS组明显,但两组间两指标变化趋势的差异均无统计学意义(F=2.022,P=0.163;F=1.703,P=0.199)。结论 NSCLC患者术后早期均出现血清VEGF及MMP-9水平的升高,变化幅度以TOS组略明显,但VATS与TOS组间的差异无统计学意义。 展开更多
关键词 肺肿瘤 胸腔镜 VEGF MMP-9
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肺小结节胸腔镜切除术前CT引导下双钩hook-wire定位的应用价值 被引量:25
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作者 黄小燕 郑屹峰 +2 位作者 潘锋 沈琦斌 邵国良 《介入放射学杂志》 CSCD 北大核心 2017年第12期1098-1101,共4页
目的探讨肺小结节胸腔镜术前CT引导下双钩hook-wire定位的应用价值。方法 54例患者共67个肺小结节病灶和63例患者共81个肺小结节病灶分别在胸腔镜切除术前行CT引导下双钩和单钩hook-wire定位,评价胸腔镜术前CT引导下双钩和单钩hook-wir... 目的探讨肺小结节胸腔镜术前CT引导下双钩hook-wire定位的应用价值。方法 54例患者共67个肺小结节病灶和63例患者共81个肺小结节病灶分别在胸腔镜切除术前行CT引导下双钩和单钩hook-wire定位,评价胸腔镜术前CT引导下双钩和单钩hook-wire定位技术的成功率、并发症发生率。结果 54例患者胸腔镜术前CT引导下肺小结节双钩hook-wire定位成功率100%,并发症有:气胸发生率29.6%(16/54)、出血发生率48.1%(26/54);63例患者胸腔镜术前CT引导下肺小结节单钩hookwire定位成功率98.4%(62/63),并发症有:气胸发生率28.5%(18/63)、出血发生率25.4%(16/63)。结论胸腔镜术前肺小结节CT引导下双钩hook-wire定位能够降低定位脱钩风险,是对其他肺小结节定位技术的重要补充。 展开更多
关键词 肺小结节 电子胸腔镜切除术 CT引导下定位 双钩钢丝
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超声引导下胸椎旁神经阻滞和菱形肌-肋间肌阻滞对胸腔镜术后恢复质量的影响 被引量:20
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作者 马楚洲 陈琼仪 +2 位作者 林梓霞 郑良杰 吴萍 《临床麻醉学杂志》 CAS CSCD 北大核心 2021年第10期1061-1064,共4页
目的观察超声引导下胸椎旁神经阻滞(TPVB)和菱形肌-肋间肌阻滞(RIB)对胸腔镜手术患者术后早期疼痛及术后康复质量的影响。方法选择全麻下行胸腔镜肺癌根治术患者78例,男51例,女27例,年龄50-70岁,ASAⅠ或Ⅱ级。随机分为两组:超声引导下T... 目的观察超声引导下胸椎旁神经阻滞(TPVB)和菱形肌-肋间肌阻滞(RIB)对胸腔镜手术患者术后早期疼痛及术后康复质量的影响。方法选择全麻下行胸腔镜肺癌根治术患者78例,男51例,女27例,年龄50-70岁,ASAⅠ或Ⅱ级。随机分为两组:超声引导下TPVB组(A组)和超声引导下RIB组(B组),每组39例。全麻诱导前,A组、B组分别采用0.33%罗哌卡因25 ml行超声引导下TPVB和RIB。记录阻滞操作时间和阻滞持续时间。记录术后2、6、24静息和活动时VAS疼痛评分。记录术后24 h内舒芬太尼用量和补救镇痛例数。记录开始进食时间、开始下地时间和术后住院时间。记录PACU低氧血症、气胸、穿刺部位出血或血肿、局麻药中毒、术后谵妄、术后肺不张、恶心呕吐等并发症的发生情况。结果B组阻滞操作时间明显短于A组(P<0.05)。两组阻滞持续时间、不同时点静息和活动时VAS疼痛评分、术后24 h内舒芬太尼用量、补救镇痛率、开始进食时间、开始下地时间、术后住院时间差异无统计学意义。两组并发症发生率差异无统计学意义。结论在胸腔镜肺癌根治术中,行超声引导下菱形肌-肋间肌阻滞的患者术后恢复质量不差于行胸椎旁神经阻滞的患者。 展开更多
关键词 菱形肌-肋间肌阻滞 胸椎旁神经阻滞 胸腔镜手术 术后早期疼痛 恢复质量
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肺小结节胸腔镜术前CT引导下Hook-wire定位的临床价值 被引量:12
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作者 王升平 李文涛 +8 位作者 彭卫军 陈海泉 何新红 李国栋 王标 胡鸿 罗小阳 沈磊 陈颖 《当代医学》 2009年第8期84-86,共3页
目的评价肺小结节胸腔镜术前CT引导下定位的价值。方法2008年2月到2008年5月共8例患者,9个小结节,行胸腔镜切除术,术前皆行CT引导下Hook-wire定位。评价术前CT引导下Hook-wire定位技术的失败率、并发症、胸腔镜手术转为开胸手术的几率... 目的评价肺小结节胸腔镜术前CT引导下定位的价值。方法2008年2月到2008年5月共8例患者,9个小结节,行胸腔镜切除术,术前皆行CT引导下Hook-wire定位。评价术前CT引导下Hook-wire定位技术的失败率、并发症、胸腔镜手术转为开胸手术的几率、住院时间等。结果共8个患者行9个结节胸腔镜切除术,术前CT引导下Hook-wire定位成功率100%,并发症发生率33%,转化为开胸手术比率为11%,中位住院时间为5天(2天~25天)。SPNs术后组织学诊断结果为:原发性肺癌4例约44.4%,转移4例约44.4%,炎性病灶1例11.1%。结论不具有典型恶性征象的SPNs约50%以上组织学诊断是恶性的,胸腔镜术前CT引导下Hook-wire定位技术极大减少开胸手术的比率、并发症发生率低,并减少住院时间,对于SPNs的鉴别诊断及治疗具有很好的临床价值。 展开更多
关键词 肺小结节 CT引导下定位 Hook—wire 胸腔镜切除术
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CT引导下Hook-wire定位对胸腔镜下肺结节治疗的应用及并发症分析 被引量:14
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作者 顾勤花 沈琦斌 +4 位作者 李鸿伟 黄小燕 李冬 谢忠海 闵伟伟 《浙江医学》 CAS 2020年第14期1469-1472,共4页
目的探讨CT引导下Hook-wire定位对胸腔镜下肺单、多发结节治疗的临床应用价值及并发症发生的影响因素。方法回顾性分析2015年2月至2019年2月湖州市中心医院收治的177例患者236枚结节在电视胸腔镜手术(VATS)切除术前行CT引导下Hook-wire... 目的探讨CT引导下Hook-wire定位对胸腔镜下肺单、多发结节治疗的临床应用价值及并发症发生的影响因素。方法回顾性分析2015年2月至2019年2月湖州市中心医院收治的177例患者236枚结节在电视胸腔镜手术(VATS)切除术前行CT引导下Hook-wire定位的临床和影像学资料,统计分析定位成功率、病理检查结果、并发症发生及其影响因素。结果236枚肺结节CT引导下定位成功率96.61%,定位时间(12.6±8.3)min,定位深度(25.43±8.23)mm,无中转开胸,VATS手术成功率100%。术后病理检查显示,恶性结节166枚(70.34%),良性结节70枚(29.66%)。定位后发生少量气胸32例(18.08%),少量血胸23例(12.99%),合并无症状气血胸患者14例(7.91%),脱钩者8例(4.52%),并发症总发生率为43.50%。多发结节患者的并发症发生率显著高于单发结节患者(P<0.05)。多因素logistic回归分析显示,肺部疾病史、进针角度、定位时间均是Hook-wire定位并发症的独立危险因素(均P<0.05)。结论Hook-wire定位是一种安全、有效、并发症轻微的VATS术前定位方法,采取适当的干预措施,对肺多发结节的定位也具有较高的可行性和有效性。 展开更多
关键词 Hook-wire定位 肺多发结节 电视胸腔镜手术 并发症 LOGISTIC回归
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CT引导下Hook-wire定位对早期肺癌术后复发率的影响 被引量:8
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作者 陈若 毛文君 +5 位作者 郑明峰 陈静瑜 何毅军 叶书高 刘峰 陆荣国 《临床肺科杂志》 2017年第2期211-216,共6页
目的探讨胸腔镜术前CT引导下Hook-wire不同定位方式,对Ⅰ期肺癌切除术后复发率的影响。方法 2010年1月至2013年12月,我院共收治了147例肺部孤立性小结节(solitary pulmonary nodule,SPN)或磨玻璃样病变(ground-glass opacity,GGO)。经... 目的探讨胸腔镜术前CT引导下Hook-wire不同定位方式,对Ⅰ期肺癌切除术后复发率的影响。方法 2010年1月至2013年12月,我院共收治了147例肺部孤立性小结节(solitary pulmonary nodule,SPN)或磨玻璃样病变(ground-glass opacity,GGO)。经过删选后共有125例患者纳入研究,其中SPN 81例,GGO 44例,所有患者胸腔镜手术前均行Hook-wire定位,68例患者接受Hook-wire穿刺针穿过病灶,57例贴近病灶定位于周围正常肺组织中。根据手术结果,评价Hook-wire不同定位方式定位的效果,对早期肺癌术后复发的影响,使用Logistic回归分析早期肺癌经Hook-wire定位切除术后复发的危险因素。结果 125例患者术前平均定位时间为(20±8)min,3例出现导丝脱落(2.4%),无症状并发症78例。所有患者均行胸腔镜下手术治疗,12例由于胸腔粘连中转开胸,术后病理:原发性肺癌76例,良性病变44例,5例为转移性肿瘤。原发性肺癌患者中,Hook-wire定位穿过病灶40例,贴近病灶定位36例,术后9例复发,前者复发率明显高于后者(20%vs 2.8%,P=0.031)。单因素和多因素Logistic回归分析显示,亚肺叶切除、病理为腺癌、Hook-wire穿过病灶定位、术前穿刺出血是术后复发的独立危险因素,术后辅助化疗为保护性因素。结论胸腔镜术前早期肺癌经CT引导下Hook-wire定位,穿过病灶定位的术后复发率高于贴近病灶定位,对于直径≤2.0 cm的早期肺癌,选择亚肺叶切除术需谨慎。 展开更多
关键词 CT引导 Hook—wire定位 早期肺癌 复发率 胸腔镜手术
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超声引导菱形肌-肋间肌-低位前锯肌平面阻滞和胸椎旁神经阻滞对胸腔镜肺叶切除术后麻醉恢复质量的影响 被引量:14
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作者 周裕凯 游星 +2 位作者 余茹 易思扬 张先杰 《川北医学院学报》 CAS 2021年第12期1649-1652,1662,共5页
目的:比较超声引导菱形肌-肋间肌-低位前锯肌平面(RISS)阻滞和胸椎旁神经阻滞(TPVB)对胸腔镜肺叶切除术患者的影响。方法:将145例经胸腔镜肺叶切除术的患者随机分为RISS组(n=73)和TPVB组(n=72)。全麻诱导前,0.25%罗哌卡因患侧单次阻滞,R... 目的:比较超声引导菱形肌-肋间肌-低位前锯肌平面(RISS)阻滞和胸椎旁神经阻滞(TPVB)对胸腔镜肺叶切除术患者的影响。方法:将145例经胸腔镜肺叶切除术的患者随机分为RISS组(n=73)和TPVB组(n=72)。全麻诱导前,0.25%罗哌卡因患侧单次阻滞,RISS组用40 mL,TPVB组用20 mL,术毕均采用患者自控静脉镇痛(PCIA)。记录准备间时(T_(0))、切皮即刻(T_(1))、手术开始30 min(T_(2))和入PACU即刻(T_(pacu))的平均动脉压(MAP)、心率(HR),术中舒芬太尼和间羟胺追加量,术后24 h康复质量评分(QoR-15);术后1、6、12、24 h静息及深呼吸时VAS评分,PCIA首次时间、术后24 h有效按压次数、曲马多补救例数及原因,术后24 h不良反应和并发症。结果:RISS组术后24 h QoR-15评分[105.0(91.5~121.5)]低于TPVB组[120.5(106.3~129.0)](P<0.05)。两组术后1 d内VAS评分均数<4分。术后1、6和12 h,RISS组VAS评分高于同时点TPVB组(P<0.05)。与TPVB组相比,RISS组PCIA首次使用时间较早,术后24 h有效按压次数和曲马多补救例数增多,T2时点的HR亦增快,且术中舒芬太尼追加量增多,但间羟胺追加量减少(P<0.05)。结论:RISS阻滞和TPVB均能有效缓解胸腔镜肺叶切除术患者的术后疼痛,且TPVB的术后康复质量和镇痛效果优于RISS阻滞。 展开更多
关键词 胸腔镜肺叶切除术 菱形肌-肋间肌-低位前锯肌平面阻滞 胸椎旁神经阻滞 超声引导
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经肋间单孔胸腔镜肺叶切除术联合消癌平对非小细胞肺癌患者miR-210和miR-101表达的影响 被引量:8
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作者 王维新 何国丽 +3 位作者 张剑锋 付红艳 左晶晶 任宏玲 《中国药业》 CAS 2023年第5期97-100,共4页
目的探讨经肋间单孔胸腔镜(IUVATS)肺叶切除术联合消癌平治疗非小细胞肺癌(NSCLC)的临床疗效,以及对患者微小RNA210(miR-210)和微小RNA101(miR-101)表达水平的影响。方法选取医院2020年4月至2021年4月收治的NSCLC患者118例,按随机数字... 目的探讨经肋间单孔胸腔镜(IUVATS)肺叶切除术联合消癌平治疗非小细胞肺癌(NSCLC)的临床疗效,以及对患者微小RNA210(miR-210)和微小RNA101(miR-101)表达水平的影响。方法选取医院2020年4月至2021年4月收治的NSCLC患者118例,按随机数字表法分为对照组和观察组,各59例。对照组患者以IUVATS肺叶切除术治疗,并辅以PE(顺铂+依托泊苷)化疗方案;观察组患者在对照组治疗基础上加用消癌平注射液。以21 d为1个化疗周期,两组均连续治疗4个周期。结果观察组患者的客观缓解率(ORR)为77.97%,疾病控制率(DCR)为88.14%,显著高于对照组的61.02%和71.19%(P<0.05)。治疗后,观察组患者的肿瘤标志物[糖类抗原199(CA199)、糖类抗原153(CA153)、人细胞角蛋白21-1片段(CYFRA21-1)]均显著低于对照组(P<0.05);T淋巴细胞亚群CD_(3)^(+),CD_(4)^(+),CD_(4)^(+)/CD_(8)^(+)均显著高于对照组,CD_(8)^(+)显著低于对照组(P<0.05);miR-210和miR-101水平均显著低于对照组(P<0.05)。治疗期间,观察组和对照组患者的不良反应发生率相当(18.64%比13.56%,P>0.05)。结论IUVATS肺叶切除术联合消癌平治疗NSCLC的临床疗效良好,能降低患者的肿瘤标志物水平,增强免疫力,抑制miR-210和miR-101的表达,且治疗安全性较好。 展开更多
关键词 非小细胞肺癌 经肋间单孔胸腔镜 肺叶切除术 消癌平 微小RNA210 微小RNA101 临床疗效
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不同的手术方案切除恶性纵膈肿瘤对患者ACTH、CRP、TNF-α、COR含量及预后影响的对比分析 被引量:15
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作者 陈均 向家勇 +3 位作者 母存富 张熠 王清海 张文林 《实用癌症杂志》 2019年第1期82-85,共4页
目的分析不同手术方案对恶性纵膈肿瘤患者的促肾上腺皮质激素(ACTH)、C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)及血浆皮质醇(COR)等指标含量、术后并发症及预后情况的影响。方法随机选取138例恶性纵膈肿瘤患者,并随机分为对照组和观察... 目的分析不同手术方案对恶性纵膈肿瘤患者的促肾上腺皮质激素(ACTH)、C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)及血浆皮质醇(COR)等指标含量、术后并发症及预后情况的影响。方法随机选取138例恶性纵膈肿瘤患者,并随机分为对照组和观察组。对照组行传统开胸手术方式治疗;治疗组行胸腔镜下微创术进行肿瘤切除。对比2组患者治疗效果,记录患者手术时间、术中出血量、术后止痛时间、术后住院时间、视觉疼痛模拟评分法(VAS)评分及手术前后CRP、ACTH、COR、TNF-α含量等指标。结果观察组的有效率为89.85%(62/69),明显高于对照组的有效率73.91%(52/69)(P <0.05)。观察组患者的术中失血量、术后止痛时间、住院时间及疼痛评分明显少于对照组;但观察组患者的手术时间为(97.96±9.84) min,略微高于对照组的(89.63±16.71) min(P <0.05)。术前,2组患者CRP、TNF-α、COR及ACTH等指标无明显差异(P> 0.05);术后,观察组CRP、TNF-α、COR及ACTH含量,明显低于对照组(P<0.05)。观察组并发症发生率为13.04%(9/69),明显低于对照组并发症发生率31.88%(22/69)(P <0.05)。结论与传统开胸手术相比,胸腔镜下微创术治疗恶性纵膈肿瘤具有患者术中出血量少、术后恢复时间短、并发症少及应激反应低等优势,值得临床推广。 展开更多
关键词 胸腔镜微创术 恶性纵膈肿瘤 免疫因子 并发症
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术前CT引导Hook-wire定位同时性多原发性肺癌的诊疗价值 被引量:9
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作者 虞桂平 单一波 +1 位作者 黄斌 姜格宁 《中国医药导报》 CAS 2019年第11期81-84,共4页
目的评估电视胸腔镜手术(VATS)术前行CT引导下Hook-wire定位对治疗同时性多原发性肺癌(SMPLC的有效性及安全性。方法回顾性分析自2011年2月~2016年12月,东南大学附属江阴市人民医院胸外科收治的SMPLC患者47例,所有患者均在CT引导下留置... 目的评估电视胸腔镜手术(VATS)术前行CT引导下Hook-wire定位对治疗同时性多原发性肺癌(SMPLC的有效性及安全性。方法回顾性分析自2011年2月~2016年12月,东南大学附属江阴市人民医院胸外科收治的SMPLC患者47例,所有患者均在CT引导下留置Hook-wire定位针,并行VATS切除病灶,根据术中冰冻病理结果决定进一步手术方式。统计定位准确率、VATS切除成功率、并发症发生率等。结果 47例SMPLC患者中,单侧SMPLC患者19例,双侧SMPLC患者28例。CT引导下带钩钢丝定位成功率为100%,定位时间为(34.98±5.95)min。患者定位后发生少量气胸(肺压缩<20%)7例(14.9%),无需处理。定位过程中发生中等量气胸(肺压缩≥20%)4例(8.6%),在手术过程中发生对侧气胸2例(4.3%),VATS探查过程中出现少量出血(≤50 m L)2例(4.3%),均未出现进行性血胸,未找到病理标本1例(2.1%),中转开胸手术2例(4.3%)。所有患者均为未发现定位针移位和脱落。结论术前CT引导下Hook-wire定位准确、安全、并发症少,对SMPLC的VATS诊治具有良好的临床价值。 展开更多
关键词 同时性多原发性肺癌 HOOK-WIRE 电视胸腔镜手术 CT扫描
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电视胸腔镜技术在原发性肺癌肺叶切除中的应用及对血清CRP和IL-6的影响 被引量:17
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作者 袁庆锋 张琪 《河北医学》 CAS 2019年第3期606-610,共5页
目的:分析电视胸腔镜技术在原发性肺癌肺叶切除中的应用及对血清C反应蛋白(CRP)和白介素-6(IL-6)的影响。方法:106例原发性肺癌患者按简单随机数字表法分为50例对照组与56例研究组。对照组采用传统开胸肺叶切除术,研究组采用电视胸腔镜... 目的:分析电视胸腔镜技术在原发性肺癌肺叶切除中的应用及对血清C反应蛋白(CRP)和白介素-6(IL-6)的影响。方法:106例原发性肺癌患者按简单随机数字表法分为50例对照组与56例研究组。对照组采用传统开胸肺叶切除术,研究组采用电视胸腔镜肺叶切除术。比较两组手术指标、术前及术后CRP、IL-6、肺功能及术后并发症。结果:研究组切口长度、术中出血量、术后疼痛时间、住院时间均优于对照组(P<0.05);两组手术时间、淋巴结清扫数目比较无统计学差异(P>0.05)。术前,两组CRP及IL-6比较无统计学差异(P>0.05);术后1d、3d,两组CRP及IL-6均上升,研究组上升幅度小于对照组(P<0.05)。术前,两组肺功能比较无统计学差异(P>0.05);两组术后CRP、IL-6、最大min通气量(MVV)、1s用力呼气容积(FEV1)、用力肺活量(FVC)比较有统计学意义,说明对照组和研究组治疗方法上有差别(P<0.05);术后1d、3d研究组CRP、IL-6均低于对照组,MVV、FEV1、FVC均高于对照组,两组不同时间点CRP、IL-6、、MVV、FEV1、FVC比较差异有统计学意义(P<0.05)。研究组术后并发症率低于对照组(P<0.05)。结论:电视胸腔镜技术在原发性肺癌肺叶切除术中的效果确切,可达到与传统开胸手术相似的手术效果,并可抑制血清CRP及IL-6过度表达,利于肺功能的恢复。 展开更多
关键词 原发性肺癌 肺叶切除术 电视胸腔镜技术 C反应蛋白 白细胞介素-6
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胸腔镜术前Hook-wire穿刺定位肺部单纯性磨玻璃样结节 被引量:7
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作者 叶红雨 黄伟钊 +3 位作者 吴颖猛 梁毅 郑俊猛 姜海明 《岭南现代临床外科》 2012年第4期359-361,共3页
目的探讨胸腔镜术前采用hook-wire穿刺定位肺部单纯性磨玻璃样结节的应用价值。方法 39例患者,共41个直径小于2cm的肺部pGGO病灶,行全胸腔镜下病灶切除术,术前均在DSAInnovaCT引导下采用hook-wire对病灶穿刺定位,对临床数据进行回顾性分... 目的探讨胸腔镜术前采用hook-wire穿刺定位肺部单纯性磨玻璃样结节的应用价值。方法 39例患者,共41个直径小于2cm的肺部pGGO病灶,行全胸腔镜下病灶切除术,术前均在DSAInnovaCT引导下采用hook-wire对病灶穿刺定位,对临床数据进行回顾性分析,对手指触诊阳性率与病灶临床因素进行相关性分析,比较手指触诊与hook-wire定位的成功率,总结hook-wire定位定位的并发症等。结果术中触诊12个病灶(29.3%)可触及并明确定位;3个病灶(7.3%)术中发现穿刺针移位;病灶的大小、深浅、病理类型、所在部位以及穿刺定位过程的时间长短,与触诊的阳性率无显著关系,39个(95.1%)病灶可通过hook-wire准确定位,与触诊比较准确性有显著差异(P<0.01);常见并发症为无症状气胸5例(12.8%),血胸2例(5.2%),严重胸痛1例(2.6%)。结论对于小于直径2cm的肺部pGGO,胸腔镜手术有必要常规进行病灶的定位,其中采用Hook-wire对病灶进行穿刺定位是一项有效、安全的技术。 展开更多
关键词 HOOK-WIRE 磨玻璃样结节 定位 胸腔镜手术
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