A feeding trial was carried out to investigate the dietary vitamin E requirement of the oriental river prawn Macrobrachium nipponense(weight of 0.3–0.4 g) and its effect role on antioxidant activity.Prawns were fed w...A feeding trial was carried out to investigate the dietary vitamin E requirement of the oriental river prawn Macrobrachium nipponense(weight of 0.3–0.4 g) and its effect role on antioxidant activity.Prawns were fed with seven levels of vitamin E(0,25,50,75,100,200,and 400 mg/kg diet) for 60 days.The results show that dietary vitamin E supplementation could significantly increased the prawn weight( P <0.05).The activity of superoxide dismutase(SOD) in the hepatopancreas was significantly higher in prawns fed with diets supplemented with ≤75 mg/kg vitamin E than in those fed with diets supplemented with 100–400 mg/kg vitamin E( P <0.05).The activity of catalase(CAT) in the hepatopancreas decreased significantly as dietary vitamin E supplementation increased( P <0.05),and no significant difference was detected in glutathione peroxidase(GSH-Px) activity between different dietary groups( P >0.05).The contents of vitamin E in the hepatopancreas and in the muscle increased with increasing dietary vitamin E.There was a linear correlation between the vitamin E level in diet and that in muscle,and between the vitamin E level in diet and that in the hepatopancreas.All the above results indicated that dietary vitamin E can be stored in the hepatopancreas and muscle and lower both the activities of SOD and CAT in the hepatopancreas,suggesting that it is a potential antioxidant in M.nipponense.Broken line analysis conducted on the weight gains of prawns in each diet group showed that the dietary vitamin E requirement for maximum growth is 94.10 mg/kg.展开更多
The activities of superoxide dismutase (SOD). glutathione peroxidase (GSH-PX) in blood and the content of melondialdehyde (MDA) in plasma of 30 Fatients (male 17, female 13) with coronary artery disease (CAD) were de...The activities of superoxide dismutase (SOD). glutathione peroxidase (GSH-PX) in blood and the content of melondialdehyde (MDA) in plasma of 30 Fatients (male 17, female 13) with coronary artery disease (CAD) were determined in this study. It was shown that SOD and GSH-PX activities were decreased and the content of MDA was increased in the Patients comparative with the healthy controls (P<0.001). Vitamin C, the free radical scavenger, was then administered intravenously with a daily dose of 2g for 2 weeks. The activities of SOD and GSB-PX were significantly elevated (P<0.01, and P<0.05, respectively). and the level of MDA was obviously declined (P<0.01). Thus,the lipid peroxidation is involved in the pathogenesis of CAD,and vitamin C possessing some effects to ameliorate the lipid peroxidation damage could be helpful in the treatment of CAE.展开更多
基金Supported by the National Natural Science Foundation of China(No.31101887)the Natural Science Foundation of Jiangsu Province(Nos.BK2011419,BK2012675)+1 种基金the Special Projects in Northern Jiangsu Province(No.BN2015107)the Jiangsu Provincial Key Laboratory of Coastal Wetland Bioresources and Environmental Protection foundation(No.JLCBE07009)
文摘A feeding trial was carried out to investigate the dietary vitamin E requirement of the oriental river prawn Macrobrachium nipponense(weight of 0.3–0.4 g) and its effect role on antioxidant activity.Prawns were fed with seven levels of vitamin E(0,25,50,75,100,200,and 400 mg/kg diet) for 60 days.The results show that dietary vitamin E supplementation could significantly increased the prawn weight( P <0.05).The activity of superoxide dismutase(SOD) in the hepatopancreas was significantly higher in prawns fed with diets supplemented with ≤75 mg/kg vitamin E than in those fed with diets supplemented with 100–400 mg/kg vitamin E( P <0.05).The activity of catalase(CAT) in the hepatopancreas decreased significantly as dietary vitamin E supplementation increased( P <0.05),and no significant difference was detected in glutathione peroxidase(GSH-Px) activity between different dietary groups( P >0.05).The contents of vitamin E in the hepatopancreas and in the muscle increased with increasing dietary vitamin E.There was a linear correlation between the vitamin E level in diet and that in muscle,and between the vitamin E level in diet and that in the hepatopancreas.All the above results indicated that dietary vitamin E can be stored in the hepatopancreas and muscle and lower both the activities of SOD and CAT in the hepatopancreas,suggesting that it is a potential antioxidant in M.nipponense.Broken line analysis conducted on the weight gains of prawns in each diet group showed that the dietary vitamin E requirement for maximum growth is 94.10 mg/kg.
文摘The activities of superoxide dismutase (SOD). glutathione peroxidase (GSH-PX) in blood and the content of melondialdehyde (MDA) in plasma of 30 Fatients (male 17, female 13) with coronary artery disease (CAD) were determined in this study. It was shown that SOD and GSH-PX activities were decreased and the content of MDA was increased in the Patients comparative with the healthy controls (P<0.001). Vitamin C, the free radical scavenger, was then administered intravenously with a daily dose of 2g for 2 weeks. The activities of SOD and GSB-PX were significantly elevated (P<0.01, and P<0.05, respectively). and the level of MDA was obviously declined (P<0.01). Thus,the lipid peroxidation is involved in the pathogenesis of CAD,and vitamin C possessing some effects to ameliorate the lipid peroxidation damage could be helpful in the treatment of CAE.
