Clinical Observation on Treatment of Moderate and Severe Periodical Mastalgia with TCM Hot-wet Compress Therapy

[Objectives] To observe the clinical therapeutic efficacy of local hot-wet compress therapy of digestion ointment prescription on the patients with moderate and severe mastalgia. [Methods] Firstly,60 patients with mastalgia were selected,and divided into the experimental group and control group( 30 cases for each group). The control group was treated with acupuncture at distal point,and the experimental group was treated with TCM local hot-wet compress therapy combined with acupuncture at distal point. Then,the clinical therapeutic efficacy of two groups was compared. [Results]The experimental group was superior to the control group in relieving the breast pain,improving emotional integral,reducing breast lumps,improving lump texture,and improving TCM syndrome integral( P < 0. 05). [Conclusions]The digestion ointment prescription local hot-wet compress therapy has a significant therapeutic effect on treatment of mastalgia and can significantly improve the breast pain symptom of patients.

Clinical Effects of the Qi-acupuncture Therapy of TCM on Portal Hypertension

Objective:To explore the effective prevention and treatment of portal hypertension(PH).Methods:A total of 220 patients who came to our hospital from March 2015 to October 2018 were treated.They were randomly divided into the treatment group and the control group,each with 110 cases.Before treatment,there was no significant differences in age,sex,clinical symptoms,signs,laboratory tests and color Doppler ultrasound related examinations between the 2 groups(P>0.05).Among them,the treatment group on the basis of traditional Chinese and Western medicine treatment in our hospital,the Qi-acupuncture therapy of TCM was added.The extra meridian acupoints along with acupoints were selected.The control group received conventional treatment with traditional Chinese and Western medicine in our hospital.Results:There were significant differences in clinical symptoms,signs and chemistry between groups after treatment(P<0.01).There were significant differences in test,color ultrasound related examination and so on(P<0.01).Those in the treatment group was significantly better than the control group(P<0.01).Conclusion:On the basis of the Qi-acupuncture therapy of TCM,selecting extra meridian acupoint and acupoints can effectively treat PH.

Non-pharmacological therapy of TCM for the treatment of essential hypertension

Non-pharmacotogicat treatment is an important means to control hypertension, with many advantages such as tow cost, tess medication, stable btood pressure, tess compHcations, and improved prognosis. This article reviews the research progress of non-drug treatment of hypertension in Chinese medicine in the past five years, and evaluates traditional Chinese medicine such as TCM Qigong, Wuhuo opera, Ba Duanjin and Taijiquan, and Chinese medicine acupuncture, moxibustion, massage, apptication, acupoint embedding and other traditional Chinese medicine. The effect of external treatment in hypertension control provides guidance for non-drug therapy to control hypertension.

Systematic review and meta analysis of the TCM therapy of Fuzheng and Kangai combined with chemotherapy in treating advanced NSCLC

Objective:To systematically evaluate TCM of Fuzheng and Kangai combined with chemotherapy in the treatment of Advanced NSCLC,including the efficacy and effect on the quality of life of patients.Methods:Two researchers independently searched the literature of clinical trails from Jan.2010 until Jun.2020 in the Cochrane Library,Pubmed,Embase,CBM,CNKI,WanFang Data and VIP database.Also,they had been evaluated and extracted strictly by REVMAN 5.3.Results:A total of 1303 patients were included in 15 articles.The meta analysis shows that the TCM of Fuzheng and Kangai combined with chemotherapy can improve the objective response rate[OR=2.14,95%CI(1.67,2.74),P<0.00001],disease control rate[OR=2.54,95%CI(1.88,3.42),P<0.00001]and KPS score[OR=3.28,95%CI(1.92,5.60),P<0.0001],decrease the incidence rate of liver injury[OR=0.34,95%CI(0.21,0.54),P=0.003],hemoglobin reduction[OR=0.53,95%CI(0.28,1.01),P=0.05],leukopenia[OR=0.22,95%CI(0.13,0.39),P<0.00001],thrombocytopenia[OR=0.32,95%CI(0.21,0.50),P<0.00001],toxic effects on the digestive systems[OR=0.30,95%CI(0.19,0.46),P<0.00001].Conclusions:the experimental group was better than control one in short-term efficacy and KPS score.Furthermore,the experimental group can reduce the incidence rate of myelosuppression,toxicity of digestive system and liver.

Effect of music therapy on chemotherapy-induced nausea and vomiting in gastrointestinal cancer:A systematic review and metaanalysis

BACKGROUND Chemotherapy is the primary treatment for patients with advanced gastrointestinal cancer,but it has many adverse reactions,particularly nausea and vomiting.Music therapy can reduce anxiety symptoms,avoid the response to the human body under various stress conditions through psychological adjustment,and improve the adverse reactions of chemotherapy.AIM To investigate the impact of music therapy on relieving gastrointestinal adverse reactions in chemotherapy for patients with digestive tract cancer by metaanalysis.METHODS EMBASE,PubMed,OVID,WoS,CNKI,CBM,and VIP database were all used for searching relevant literature,and the efficacy after treatment was combined for analysis and evaluation.RESULTS This study included seven articles.The results of meta-analysis indicated that music therapy could reduce the nausea symptom score of patients after chemotherapy[mean difference(MD)=-3.15,95%confidence interval(CI):-4.62 to-1.68,Z=-4.20,P<0.0001].Music therapy could reduce the vomiting symptom score of patients after chemotherapy(MD=-2.28,95%CI:-2.46 to-2.11,Z=-25.15,P<0.0001).Furthermore,music therapy could minimize the incidence of grade I and above nausea or vomiting in patients after chemotherapy(odds ratio=0.38,95%CI:0.26-0.56,Z=-4.88,P<0.0001).Meta-regression analysis found that publication year was not a specific factor affecting the combined results.There was no significant publication bias(P>0.05).CONCLUSION Music therapy can significantly improve the scores of nausea and vomiting symptoms in patients with digestive system cancer during chemotherapy and reduce the incidence of grade I and above nausea and vomiting after chemotherapy,making it an effective psychological intervention method worthy of clinical promotion.

Comprehensive interventions for adult cyclic vomiting syndrome complicated by superior mesenteric artery syndrome:A case report

BACKGROUND Cyclic vomiting syndrome(CVS)is a chronic functional gastrointestinal disorder involving the gut–brain interaction that is characterized by recurring episodes of nausea,vomiting,abdominal pain,and interspersed complete normal periods.Superior mesenteric artery(SMA)syndrome(SMAS)is a vascular condition in which the horizontal portion of the duodenum is compressed due to a reduced angle between the aorta and the SMA.This condition presents with symptoms similar to CVS,posing challenges in distinguishing between the two and often resulting in misdiagnosis or inappropriate treatment.CASE SUMMARY A 20-year-old female patient presented with recurrent episodes of vomiting and experienced a persistent fear of vomiting for the past 2 years.She adopted conscious dietary restrictions,which led to severe malnutrition.Initially,she was diagnosed with SMAS,as revealed by computed tomography angiography.Despite efforts to increase the angle between the aorta and the SMA through weight gain,her vomiting did not improve.Finally,she was diagnosed with comorbidities including CVS,SMAS and anxiety disorder.She underwent comprehensive interventions,including enteral and parenteral nutritional supplementation,administration of antiemetic and anti-anxiety agents,and participation in mindfulness-based cognitive therapy.The patient eventually experienced a notable improvement in both body weight and clinical symptoms.CONCLUSION We present a rare case of CVS in an adult complicated with SMAS and propose additional treatment with nutritional support,pharmacological intervention,and psychotherapy.

Non-pharmacological management for chemotherapy-induced nausea and vomiting in patients with cancer:a scoping review

Objective:This review aimed to map and summarize published studies that tested non-pharmacological management for chemotherapyinduced nausea and vomiting(CINV).Methods:We searched for eligible studies in 5 electronic databases and screened the retrieved studies using the inclusion and exclusion criteria.Data were then collated according to the types of interventions,measurement tool,and outcomes.Results:The search yielded 2343 records,of which 11 were included.Four categories of non-pharmacological CINV management were made;manipulative and body-based therapy(n=5 studies);mind–body therapy(n=3 studies);biologically based practice(n=1 study),and energy therapy(n=2 studies).Seven different scales were used to measure CINV.Nine studies repor ted improvement in CINV.Conclusions:This scoping review demonstrates the breadth of non-pharmacological management to address CINV.Various types of CINV scales were used to measure CINV severity.The management and scale can be utilized to improve nursing care,par ticularly in cancer care.

Auricular therapy for chemotherapy-induced nausea and vomiting in cancer patients:Perspectives from the traditional zang-fu organs and meridians theory

This paper presents the theoretical background of using auricular therapy(AT)for managing chemotherapy-induced nausea and vomiting(CINV)from the perspectives of traditional zang-fu organs and meridian theory.The zang-fu organs of stomach,spleen and liver play a crucial role in regulating the gastrointestinal functions.The chemotherapeutic agents can significantly impede the gastrointestinal functions and subsequently contribute to various gastrointestinal symptoms including nausea and vomiting.Dysfunctions of the stomach,spleen and liver can correspond to specific auricular acupoints,while by stimulating those acupoints,the chaotic Qi movement can be reversed to its normal status,and the hyperactivities of the gastrointestinal system can also be alleviated to reduce the CINV symptoms.Clinical studies based on such theory have well supported the effects of AT on CINV.However,relationships between the traditional theory and the modern medicine understanding of the CINV mechanisms remain unknown and should be further explored in future research.

Influence of TCM Therapy for Supplementing Pi(脾) and Nourishing Shen(肾) on Dendritic Cell Function in Patients with Chronic Hepatitis B Treated by Lamivudine

Objective:To observe the influence of traditional Chinese medicine(TCM) therapy for supplementing Pi(脾) and nourishing Shen(肾,SPNS) on dendritic cell function in patients with chronic hepatitis B (CHB) treated by lamivudine.Methods:Sixty CHB patients with positive HBeAg were equally randomized by digital table into two groups:the observation group and the control group.Patients in the control group were treated with lamivudine only,while patients in the observation group were treated with lamivudine combine...

Acupuncture in preventing postoperative nausea and vomiting:a systematic review and Bayesian network meta-analysis

However,the best choice of acupuncture therapy for postoperative nausea and vomiting remains controversy.Methods:Several databases were searched from inception to April 2020.Randomized controlled trials met the criterion were included.Risk of bias was implemented with Cochrane risk-of-bias tool.Addis,R,OpenBUGS and STATA were used to conduct meta-analysis.The evidence was assessed by GRADE profiler 3.6.Results:Fifty studies involving 5980 patients were included.The risk of bias of most included studies were acceptable.The results of network meta-analyses indicated,compared with placebo,electroacupuncture was the best choice for postoperative nausea(odds ratio=0.09,95%confidence interval:0.02-0.51)and acupoint plaster for postoperative vomiting(odds ratio=0.07,95%confidence interval:0.01-0.42),acupoint catgut embedding+5HTRA for postoperative nausea and vomiting(odds ratio=0.05,95%confidence interval:0.01-0.15),and transcutaneous electrical nerve stimulation+5-hydroxytryptamine receptor antagonists for postoperative rescue antiemetics(odds ratio=0.14,95%confidence interval:0.08-0.46).Conclusion:It was suggested transcutaneous electrical nerve stimulation+5-hydroxytryptamine receptor antagonists was the best choice.The results provided guidance for the prevention of postoperative nausea and vomiting.

血府逐瘀汤治疗冠心病研究进展

冠心病是临床常见的心血管疾病之一,其发病率和病死率呈上升趋势,严重危害居民健康,加重国家经济负担。血府逐瘀汤有活血化瘀、理气止痛的功效,主治胸中血瘀证。临床上根据其功效常用于治疗血瘀证冠心病,并取得良好疗效。此文旨在对血府逐瘀汤治疗冠心病的临床运用、作用机制及研究进展展开探讨,为深入挖掘血府逐瘀汤临床及实验研究提供新思路。

八段锦联合放松功对轻中度抑郁的影响研究

【目的】探究中医行为心理疗法八段锦联合放松功干预轻中度抑郁的效果。【方法】将40例轻中度抑郁患者随机分为干预组和对照组,每组各20例。干预组给予八段锦锻炼联合放松功干预治疗,对照组给予西药氢溴酸西酞普兰片治疗,疗程为6周。观察2组患者干预前后汉密尔顿抑郁量表(HAMD)评分、蒙哥马利抑郁量表(MADRS)评分、匹兹堡睡眠质量指数(PSQI)评分以及生活质量综合评定问卷(GQOL-74)评分的变化情况,并评价2组患者的抑郁改善疗效。【结果】(1)抑郁改善疗效方面,治疗6周后,干预组的总有效率为95.0%(19/20),对照组为90.0%(18/20),组间比较(χ2检验),差异无统计学意义(P>0.05)。(2)抑郁程度方面,治疗后,2组患者的HAMD评分和MADRS评分均较治疗前明显下降(P<0.01),但治疗后组间比较,差异均无统计学意义(P>0.05)。(3)生活质量方面,治疗后,2组患者的GQOL-74的躯体功能、心理功能、社会功能、物质生活等各项评分及总分均较治疗前明显改善(P<0.01),但治疗后组间比较,差异均无统计学意义(P>0.05)。(4)睡眠质量方面,治疗后,2组患者的PSQI的睡眠质量、入睡时间、睡眠时间、睡眠效率、睡眠障碍、催眠药物和日间功能等各项评分及总分均较治疗前明显改善(P<0.01),且干预组对PSQI的睡眠质量、入睡时间评分及总分的改善作用明显优于对照组(P<0.05)。【结论】八段锦锻炼联合放松功干预对轻中度抑郁症状的改善有明确的疗效,可以为轻中度抑郁症患者提供更广泛的选择可能,特别是对西药治疗不耐受的患者更具有一定的优势。

中医药治疗特发性肺纤维化研究进展

特发性肺纤维化是原因不明的慢性进行性致纤维化间质性肺炎,主要见于中老年男性,局限于肺,临床上呈渐进性呼吸困难和肺功能恶化,组织病理学和胸部HRCT表现为特征性的寻常型间质性肺炎。特发性肺纤维化属中医学“肺痿、肺痹”范畴,中医对此病的认识历史悠久,优势明显,近年来受到越来越多的重视,通过对近5年多(2018年—至今)中医药在特发性肺纤维化的研究文献进行总结,主要从病机(“肺虚络瘀”论、“热毒滞络”论、“肺寒络凝”论、其他)、临床研究(古方、自拟方、中成药、六字诀呼吸操、热敏灸)2方面进行了综述,以期为此病的治疗提供有益的参考。

隐性听力损失中医病机及防治研究进展

隐性听力损失是以纯音听阈正常,噪声背景下言语识别能力降低为主要症状的疾病,噪声暴露、药物损伤、年龄老化是主要的致病危险因素,其发病隐匿,容易忽视,危险因素持续暴露可造成不可逆听力损伤,目前临床多无有效的治疗方法,以早期预防为主。根据隐性听力损失的致病因素及发病机制,探讨隐性听力损失的中医病机,认为脾虚湿滞、清窍蒙蔽、肾元不足、邪聚耳窍为致病的内在因素,毒邪犯耳、内毒留滞、毒瘀经络为病理机制,并对近年来隐性听力损失的预防与治疗研究概况做一总结,为中医药治疗隐性听力损失研究提供理论依据和临床经验。

中药穴位贴敷联合音乐疗法对宫颈癌化疗所致恶心呕吐的干预效果分析

目的观察中药穴位贴敷联合音乐疗法对宫颈癌化疗所致恶心呕吐的干预效果。方法纳入宫颈癌化疗治疗所致恶心呕吐的患者76例,采用随机数字表法分为2组。对照组37例予音乐疗法,研究组39例予中药穴位贴敷联合音乐疗法干预。2组均21天为1个疗程,治疗4个疗程。比较2组治疗前后血小板计数、白细胞计数、血红蛋白水平、恶心及呕吐指数评估量表(INVR)和生活质量评分(QOL),记录2组恶心呕吐发生情况,统计对比2组疗效。结果研究组总有效率92.31%(36/39),对照组总有效率72.97%(27/37),研究组临床疗效优于对照组(P<0.05)。2组治疗后血小板计数、白细胞计数及血红蛋白水平均较本组治疗前降低(P<0.05),且研究组治疗后均低于对照组(P<0.05)。2组治疗前后INVR评分比较2组治疗后INVR各项评分均较本组治疗前降低(P<0.05),且研究组治疗后均低于对照组(P<0.05)。2组治疗后QOL各项评分均较本组治疗前升高(P<0.05),且研究组治疗后均高于对照组(P<0.05)。2组治疗当日恶心呕吐发生情况比较差异无统计学意义(P>0.05)。治疗结束后当日研究组恶心呕吐发生率均低于对照组(P<0.05)。结论经中药穴位贴敷联合音乐疗法对宫颈癌化疗所致恶心呕吐患者进行治疗,能显著改善患者恶心呕吐症状,提高患者生活质量,临床效果显著。

调补脾肾中药复方治疗原发性骨质疏松症临床研究

目的:观察调补脾肾中药复方治疗原发性骨质疏松症(primary osteoporosis,POP)的临床疗效。方法:POP患者共计60例,采用随机数字表法随机分为对照组(30例)和治疗组(30例)。对照组治疗方法为常规综合治疗,治疗组治疗方法为在对照组的基础上加用调补脾肾中药复方。比较2组患者的骨密度、血清碱性磷酸酶(ALP)、血红蛋白(Hb)、白蛋白(ALB)、血钙(Ca)、血磷(P)及临床疗效。结果:治疗组总有效率高于对照组(P<0.05)。治疗后,2组的ALP水平均降低,治疗组低于对照组(P<0.05),Hb、ALB水平及骨密度均提高,三个指标相比较治疗组高于对照组(P<0.05)。结论:POP用调补脾肾中药复方治疗效果明确,能有效调节ALP、Hb、ALB水平,提高骨密度。

中医外治法治疗痛风性关节炎研究文献可视化分析

目的 分析中医外治法治疗痛风性关节炎相关文献,了解该领域研究现状、研究热点和发展趋势,为该领域后续研究提供研究思路。方法 检索中国知识资源总库(CNKI)、中国学术期刊数据库(万方数据)、中文科技期刊数据库(VIP)2000年1月1日-2022年11月30日收录的中医外治法治疗痛风性关节炎研究文献,利用NoteExpress3.6.0软件对文献进行人工筛选,借助Excel2019绘制发文趋势图和期刊分布图;采用VOSviewer1.6.18软件绘制核心作者合作网络、机构合作密度视图和关键词共现图谱,使用CiteSpace6.1.R4软件绘制关键词聚类分析图、时间线图及关键词突现图谱,并对以上内容进行分析。结果 共纳入1 304篇文献,发文量总体呈增长态势;纳入文献涉及318本期刊、2 890位作者,发文量最多的是广州中医药大学;分析得出文献关键词1 181个,形成12个有意义的聚类,并展现出了湿热蕴结型、炎性因子、中医药疗法等20个突现词。结论 中医外治法治疗痛风性关节炎的研究热点主要集中于中药内服外敷、临床疗效观察及中药外敷、针刺、刺血疗法、电针、火针、针刀等中医外治法,备受关注的中医证型是湿热蕴结型。

温针配合穴位贴敷及药物干预乳腺癌化疗相关性恶心呕吐的临床研究

目的观察温针配合穴位贴敷及药物干预乳腺癌化疗相关性恶心呕吐(chemotherapy induced nausea and vomiting,CINV)的临床疗效。方法将110例乳腺癌术后辅助化疗患者随机分为观察组和对照组,每组55例。对照组于化疗前30 min接受静脉滴注注射用盐酸托烷司琼治疗,观察组在对照组基础上于化疗前1 d接受温针配合穴位贴敷治疗。观察两组化疗前后不同时间点恶心、呕吐反应症状评分及血清5-羟色胺(5-hydroxytryptamine,5-HT)水平的变化情况,并比较两组CINV发生率。结果观察组CINV发生率为34.5%,明显低于对照组的56.4%,差异具有统计学意义(P<0.05)。两组化疗后第3 d恶心、呕吐反应症状评分均较同组化疗前显著上升,化疗后第5、7 d恶心、呕吐反应症状评分均较同组化疗第3 d显著下降,差异均具有统计学意义(P<0.05)。观察组化疗后第3、5、7 d恶心、呕吐反应症状评分均明显低于对照组,差异均具有统计学意义(P<0.05)。两组化疗后第7 d血清5-HT水平均较同组化疗前显著上升(P<0.05)。观察组化疗后第7 d血清5-HT水平明显低于对照组,差异具有统计学意义(P<0.05)。结论温针配合穴位贴敷及药物干预能降低乳腺癌CINV的发生率,有助于缓解恶心、呕吐症状,其机制可能与降低5-HT水平有关。

王海东主任医师治疗强直性脊柱炎临床经验思辨

王海东主任医师认为强直性脊柱炎属本虚标实之证,以肝肾亏虚、气血不足、脾胃虚弱为本,寒、湿、瘀等实邪偏盛为标。王海东主任医师主张分期分型辨证论治,巧用药对并全程注重调护脾胃。

芪葛威灵胶囊治疗糖尿病周围神经病变临床观察

目的:观察芪葛威灵胶囊治疗气阴两虚兼血瘀型糖尿病周围神经病变患者的临床疗效。方法:选取120例气阴两虚兼血瘀型糖尿病神经病变患者,按随机数字表法分为两组各60例。治疗组予芪葛威灵胶囊治疗,对照组予甲钴胺片口服。治疗8周后,比较两组患者临床疗效、中医证候积分、多伦多临床评分系统(TCSS)评分、神经传导速度、不良反应等。结果:治疗组总有效率91.67%,优于对照组的68.33%(P﹤0.05);治疗后,两组患者肢体麻木、疼痛及小腿抽搐证候积分均明显下降(P﹤0.05),两组TCSS评分均明显降低(P﹤0.05),腓总神经、胫后神经运动神经传导速度均明显提高(P﹤0.05),且治疗组改善程度均优于对照组(P﹤0.05)。结论:芪葛威灵胶囊可改善气阴两虚兼血瘀型糖尿病周围神经病变患者的临床症状,提高TCSS评分、改善神经传导速度,临床疗效良好。