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Enhancing Iterative Learning Control With Fractional Power Update Law
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作者 Zihan Li Dong Shen Xinghuo Yu 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2023年第5期1137-1149,共13页
The P-type update law has been the mainstream technique used in iterative learning control(ILC)systems,which resembles linear feedback control with asymptotical convergence.In recent years,finite-time control strategi... The P-type update law has been the mainstream technique used in iterative learning control(ILC)systems,which resembles linear feedback control with asymptotical convergence.In recent years,finite-time control strategies such as terminal sliding mode control have been shown to be effective in ramping up convergence speed by introducing fractional power with feedback.In this paper,we show that such mechanism can equally ramp up the learning speed in ILC systems.We first propose a fractional power update rule for ILC of single-input-single-output linear systems.A nonlinear error dynamics is constructed along the iteration axis to illustrate the evolutionary converging process.Using the nonlinear mapping approach,fast convergence towards the limit cycles of tracking errors inherently existing in ILC systems is proven.The limit cycles are shown to be tunable to determine the steady states.Numerical simulations are provided to verify the theoretical results. 展开更多
关键词 Asymptotic convergence convergence rate finiteiteration tracking fractional power learning rule limit cycles
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Chimp Optimization Algorithm Based Feature Selection with Machine Learning for Medical Data Classification
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作者 Firas Abedi Hayder M.A.Ghanimi +6 位作者 Abeer D.Algarni Naglaa F.Soliman Walid El-Shafai Ali Hashim Abbas Zahraa H.Kareem Hussein Muhi Hariz Ahmed Alkhayyat 《Computer Systems Science & Engineering》 SCIE EI 2023年第12期2791-2814,共24页
Datamining plays a crucial role in extractingmeaningful knowledge fromlarge-scale data repositories,such as data warehouses and databases.Association rule mining,a fundamental process in data mining,involves discoveri... Datamining plays a crucial role in extractingmeaningful knowledge fromlarge-scale data repositories,such as data warehouses and databases.Association rule mining,a fundamental process in data mining,involves discovering correlations,patterns,and causal structures within datasets.In the healthcare domain,association rules offer valuable opportunities for building knowledge bases,enabling intelligent diagnoses,and extracting invaluable information rapidly.This paper presents a novel approach called the Machine Learning based Association Rule Mining and Classification for Healthcare Data Management System(MLARMC-HDMS).The MLARMC-HDMS technique integrates classification and association rule mining(ARM)processes.Initially,the chimp optimization algorithm-based feature selection(COAFS)technique is employed within MLARMC-HDMS to select relevant attributes.Inspired by the foraging behavior of chimpanzees,the COA algorithm mimics their search strategy for food.Subsequently,the classification process utilizes stochastic gradient descent with a multilayer perceptron(SGD-MLP)model,while the Apriori algorithm determines attribute relationships.We propose a COA-based feature selection approach for medical data classification using machine learning techniques.This approach involves selecting pertinent features from medical datasets through COA and training machine learning models using the reduced feature set.We evaluate the performance of our approach on various medical datasets employing diverse machine learning classifiers.Experimental results demonstrate that our proposed approach surpasses alternative feature selection methods,achieving higher accuracy and precision rates in medical data classification tasks.The study showcases the effectiveness and efficiency of the COA-based feature selection approach in identifying relevant features,thereby enhancing the diagnosis and treatment of various diseases.To provide further validation,we conduct detailed experiments on a benchmark medical dataset,revealing the superiority of the MLARMCHDMS model over other methods,with a maximum accuracy of 99.75%.Therefore,this research contributes to the advancement of feature selection techniques in medical data classification and highlights the potential for improving healthcare outcomes through accurate and efficient data analysis.The presented MLARMC-HDMS framework and COA-based feature selection approach offer valuable insights for researchers and practitioners working in the field of healthcare data mining and machine learning. 展开更多
关键词 Association rule mining data classification healthcare data machine learning parameter tuning data mining feature selection MLARMC-HDMS COA stochastic gradient descent Apriori algorithm
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Multi-modal knowledge graph inference via media convergence and logic rule
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作者 Feng Lin Dongmei Li +5 位作者 Wenbin Zhang Dongsheng Shi Yuanzhou Jiao Qianzhong Chen Yiying Lin Wentao Zhu 《CAAI Transactions on Intelligence Technology》 SCIE EI 2024年第1期211-221,共11页
Media convergence works by processing information from different modalities and applying them to different domains.It is difficult for the conventional knowledge graph to utilise multi-media features because the intro... Media convergence works by processing information from different modalities and applying them to different domains.It is difficult for the conventional knowledge graph to utilise multi-media features because the introduction of a large amount of information from other modalities reduces the effectiveness of representation learning and makes knowledge graph inference less effective.To address the issue,an inference method based on Media Convergence and Rule-guided Joint Inference model(MCRJI)has been pro-posed.The authors not only converge multi-media features of entities but also introduce logic rules to improve the accuracy and interpretability of link prediction.First,a multi-headed self-attention approach is used to obtain the attention of different media features of entities during semantic synthesis.Second,logic rules of different lengths are mined from knowledge graph to learn new entity representations.Finally,knowledge graph inference is performed based on representing entities that converge multi-media features.Numerous experimental results show that MCRJI outperforms other advanced baselines in using multi-media features and knowledge graph inference,demonstrating that MCRJI provides an excellent approach for knowledge graph inference with converged multi-media features. 展开更多
关键词 logic rule media convergence multi-modal knowledge graph inference representation learning
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EQUAL INTERVAL RANGE APPROXIMATION AND EXPANDING LEARNING RULE FOR MULTI-LAYER PERCEPTRONS AND APPLICATIONS
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作者 王尧广 刘泽民 周正 《Journal of Electronics(China)》 1992年第4期327-335,共9页
In this paper,we propose an equal interval range approximation and expandinglearning rule for multi-layer perceptrons applied in pattern recognitions.Compared with tra-ditional BP algorithm,this learning rule requires... In this paper,we propose an equal interval range approximation and expandinglearning rule for multi-layer perceptrons applied in pattern recognitions.Compared with tra-ditional BP algorithm,this learning rule requires the output activations interval between themaximum target output node and other nodes to exceed a given equal interval range for eachtraining input pattern,thus it can train networks faster in much lower calculation cost andmay avoid the occurrences ot reversed target output and overlearning,hence it can improve thenetwork’s generalization abilities in pattern recognitions.Through gradually expanding of theinterval range,this learning rule can also enable the network to learn its targets more accuratelyin less additional training iterations.Finally,we apply this algorithm in network training inEEG detection,and the experimental results have shown the above advantages of the proposedalgorithm. 展开更多
关键词 NEURAL network Pattern recognition Equal INTERVAL RANGE APPROXIMATION EXPANDING learning rule
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Operating Rule Classification System of Water Supply Reservoir Based on Learning Classifier System
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作者 张先锋 王小林 +1 位作者 尹正杰 李惠强 《Journal of Southwest Jiaotong University(English Edition)》 2008年第3期275-284,共10页
An operating rule classification system based on learning classifier system (LCS), which learns through credit assignment (bucket brigade algorithm, BBA) and rule discovery (genetic algorithm, GA), is establishe... An operating rule classification system based on learning classifier system (LCS), which learns through credit assignment (bucket brigade algorithm, BBA) and rule discovery (genetic algorithm, GA), is established to extract water-supply reservoir operating rules. The proposed system acquires an online identification rate of 95% for training samples and an offline rate of 85% for testing samples in a case study. The performances of the rule classification system are discussed from the rationality of the obtained rules, the impact of training samples on rule extraction, and a comparison between the rule classification system and the artificial neural network (ANN). The results indicate that the LCS is feasible and effective for the system to obtain the reservoir supply operating rules. 展开更多
关键词 Operating rules Water supply learning classifier system Genetic algorithm
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The Adaptation of Mobile Learning System Based on Business Rules
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作者 LIN Jinjiao (School of Information Management Shandong Economic University Jinan 250100,China) 《Journal of Measurement Science and Instrumentation》 CAS 2010年第S1期190-191,198,共3页
In the mobile learning system,it is important to adapt to mobile devices.Most of mobile learning systems are not quickly suitable for mobile devices.In order to provide adaptive mobile services,the approach for adapta... In the mobile learning system,it is important to adapt to mobile devices.Most of mobile learning systems are not quickly suitable for mobile devices.In order to provide adaptive mobile services,the approach for adaptation is proposed in this paper.Firstly,context of mobile devices and its influence on mobile learning system are analized and business rules based on these analysis are presented.Then,using the approach,the mobile learning system is constructed.The example implies this approach can adapt the mobile service to the mobile devices flexibly. 展开更多
关键词 MOBILE learning SYSTEM MOBILE DEVICES BUSINESS Rul
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Sound transducer calibration of ambulatory audiometric system utilizing delta learning rule
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作者 KIM Kyeong-seop SHIN Seung-won +3 位作者 YOON Tae-ho LEE Sang-min LEE Insung RYU Keun ho 《Journal of Central South University》 SCIE EI CAS 2011年第6期2009-2014,共6页
An efficient calibration algorithm for an ambulatory audiometric test system is proposed. This system utilizes a personal digital assistant (PDA) device to generate the correct sound pressure level (SPL) from an audio... An efficient calibration algorithm for an ambulatory audiometric test system is proposed. This system utilizes a personal digital assistant (PDA) device to generate the correct sound pressure level (SPL) from an audiometric transducer such as an earphone. The calibrated sound intensities for an audio-logical examination can be obtained in terms of the sound pressure levels of pure-tonal sinusoidal signals in eight-banded frequency ranges (250, 500, 1 000, 2 000, 3 000, 4 000, 6 000 and 8 000 Hz), and with mapping of the input sound pressure levels by the weight coefficients that are tuned by the delta learning rule. With this scheme, the sound intensities, which evoke eight-banded sound pressure levels by 5 dB steps from a minimum of 25 dB to a maximum of 80 dB, can be generated without volume displacement. Consequently, these sound intensities can be utilized to accurately determine the hearing threshold of a subject in the ambulatory audiometric testing environment. 展开更多
关键词 传感器校准 声音强度 规则系统 三角洲 门诊 听力 个人数字助理 声压级
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Tunable structure priors for Bayesian rule learning for knowledge integrated biomarker discovery
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作者 Jeya Balaji Balasubramanian Vanathi Gopalakrishnan 《World Journal of Clinical Oncology》 CAS 2018年第5期98-109,共12页
AIM To develop a framework to incorporate background domain knowledge into classification rule learning for knowledge discovery in biomedicine.METHODS Bayesian rule learning(BRL) is a rule-based classifier that uses a... AIM To develop a framework to incorporate background domain knowledge into classification rule learning for knowledge discovery in biomedicine.METHODS Bayesian rule learning(BRL) is a rule-based classifier that uses a greedy best-first search over a space of Bayesian belief-networks(BN) to find the optimal BN to explain the input dataset, and then infers classification rules from this BN. BRL uses a Bayesian score to evaluate the quality of BNs. In this paper, we extended the Bayesian score to include informative structure priors, which encodes our prior domain knowledge about the dataset. We call this extension of BRL as BRL_p. The structure prior has a λ hyperparameter that allows the user to tune the degree of incorporation of the prior knowledge in the model learning process. We studied the effect of λ on model learning using a simulated dataset and a real-world lung cancer prognostic biomarker dataset, by measuring the degree of incorporation of our specified prior knowledge. We also monitored its effect on the model predictive performance. Finally, we compared BRL_p to other stateof-the-art classifiers commonly used in biomedicine.RESULTS We evaluated the degree of incorporation of prior knowledge into BRL_p, with simulated data by measuring the Graph Edit Distance between the true datagenerating model and the model learned by BRL_p. We specified the true model using informative structurepriors. We observed that by increasing the value of λ we were able to increase the influence of the specified structure priors on model learning. A large value of λ of BRL_p caused it to return the true model. This also led to a gain in predictive performance measured by area under the receiver operator characteristic curve(AUC). We then obtained a publicly available real-world lung cancer prognostic biomarker dataset and specified a known biomarker from literature [the epidermal growth factor receptor(EGFR) gene]. We again observed that larger values of λ led to an increased incorporation of EGFR into the final BRL_p model. This relevant background knowledge also led to a gain in AUC.CONCLUSION BRL_p enables tunable structure priors to be incorporated during Bayesian classification rule learning that integrates data and knowledge as demonstrated using lung cancer biomarker data. 展开更多
关键词 Supervised machine learning rule-BASED models BAYESIAN methods Background KNOWLEDGE INFORMATIVE PRIORS BIOMARKER discovery
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基于Q-learning的机会频谱接入信道选择算法 被引量:9
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作者 张凯 李鸥 杨白薇 《计算机应用研究》 CSCD 北大核心 2013年第5期1467-1470,共4页
针对未知环境下机会频谱接入的信道选择问题进行研究。将智能控制中的Q-learning理论应用于信道选择问题,建立次用户信道选择模型,提出了一种基于Q-learning的信道选择算法。该算法通过不断与环境进行交互和学习,引导次用户尽量选择累... 针对未知环境下机会频谱接入的信道选择问题进行研究。将智能控制中的Q-learning理论应用于信道选择问题,建立次用户信道选择模型,提出了一种基于Q-learning的信道选择算法。该算法通过不断与环境进行交互和学习,引导次用户尽量选择累积回报最大的信道,最大化次用户吞吐量。引入Boltzmann学习规则在信道探索与利用之间获得折中。仿真结果表明,与随机选择算法相比,该算法在不需要信道环境先验知识或预测模型下,能够自适应地选择可用性较好的信道,有效提高次用户吞吐量,且收敛速度较快。 展开更多
关键词 认知无线电 机会频谱接入 Q学习 信道选择 Boltzmann规则
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基于一阶逻辑的个性化E-Learning本体推理研究 被引量:2
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作者 冯瑶 冯锡炜 黄越洋 《辽宁石油化工大学学报》 CAS 2016年第1期65-70,共6页
针对OWL DL推理和表达能力的局限性,提出一种基于一阶逻辑FOL的推理方法,并将该方法应用到个性化E-Learning领域。构建了E-Learning领域本体库,将OWL DL本体映射为FOL本体,并使用FOL制定E-Leaning资源的个性化匹配规则,最后使用一阶定... 针对OWL DL推理和表达能力的局限性,提出一种基于一阶逻辑FOL的推理方法,并将该方法应用到个性化E-Learning领域。构建了E-Learning领域本体库,将OWL DL本体映射为FOL本体,并使用FOL制定E-Leaning资源的个性化匹配规则,最后使用一阶定理证明器进行推理,并比较了3种一阶定理证明器的推理结果。实验结果表明,通过FOL对OWL DL本体进行推理是可行的,能够使推理能力和表达能力达到完美平衡。 展开更多
关键词 本体 推理规则 OWL 一阶逻辑 E-learning本体
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E-Learning系统的个性化推荐方法研究 被引量:2
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作者 石宜金 马瑞英 贾志洋 《信息技术与信息化》 2012年第2期51-54,共4页
以E-Learning系统建设为背景,通过采用文献查找、调查研究等方法探讨个性化推荐理论的内涵,并结合当前建设中的E-Learning系统,分析了目前常用的个性化推荐策略,并进行介绍比较和分析以后,总结经验,以应用于E-Learning系统的建设。提出... 以E-Learning系统建设为背景,通过采用文献查找、调查研究等方法探讨个性化推荐理论的内涵,并结合当前建设中的E-Learning系统,分析了目前常用的个性化推荐策略,并进行介绍比较和分析以后,总结经验,以应用于E-Learning系统的建设。提出适合于E-learning系统建设的个性化推荐策略:采用关联规则推荐策略和协同过滤技术,基于WEB技术建立一个虚拟学习系统,利用推荐算法,结合用户需求,将学习的资源、学习活动和学习策略进行整合,向用户推荐完整的满足用户需求的E-Learning学习方案。 展开更多
关键词 数字化学习 个性化推荐 推荐系统 协同过滤 关联规则
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E-Learning环境下基于知识点偏好的学习社区组建
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作者 赵海燕 王传安 葛华 《重庆科技学院学报(自然科学版)》 CAS 2015年第3期98-102,共5页
在对在线学习者的个性化信息进行抽象、合理描述及分析的基础上,提出描述学习者在学习过程中的本体模型及本体推理规则;在结合虚拟学习社区和知识导航的服务下,借助Protégé、JSP和Jena编程技术,实现基于本体并具有组建虚拟学... 在对在线学习者的个性化信息进行抽象、合理描述及分析的基础上,提出描述学习者在学习过程中的本体模型及本体推理规则;在结合虚拟学习社区和知识导航的服务下,借助Protégé、JSP和Jena编程技术,实现基于本体并具有组建虚拟学习社区和知识导航功能的E-Learning原型系统。实验表明,所提出的建模方法有利于进一步建立基于知识偏好的学习社区。 展开更多
关键词 E-learning环境 本体模型 推理规则 虚拟学习社区
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基于关联规则挖掘的e-Learning系统中个性化学习推荐 被引量:2
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作者 浦慧忠 《安徽电子信息职业技术学院学报》 2013年第1期17-20,25,共5页
随着信息时代与学习型社会的来临,基于因特网技术面向个性化学习的e_Learning的研究受到了普遍重视。本文基于Web挖掘中关联规则的经典Apriori算法,通过对学生高频访问路径和最大向前访问路径两个方面的挖掘,调整系统结构,从而实现向学... 随着信息时代与学习型社会的来临,基于因特网技术面向个性化学习的e_Learning的研究受到了普遍重视。本文基于Web挖掘中关联规则的经典Apriori算法,通过对学生高频访问路径和最大向前访问路径两个方面的挖掘,调整系统结构,从而实现向学生进行个性化学习内容的推荐。 展开更多
关键词 个性化学习 WEB挖掘 关联规则 高频访问路径 最大向前访问路径
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FAST RECURSIVE LEAST SQUARES LEARNING ALGORITHM FOR PRINCIPAL COMPONENT ANALYSIS 被引量:8
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作者 Ouyang Shan Bao Zheng Liao Guisheng(Guilin Institute of Electronic Technology, Guilin 541004)(Key Laboratory of Radar Signal Processing, Xidian Univ., Xi’an 710071) 《Journal of Electronics(China)》 2000年第3期270-278,共9页
Based on the least-square minimization a computationally efficient learning algorithm for the Principal Component Analysis(PCA) is derived. The dual learning rate parameters are adaptively introduced to make the propo... Based on the least-square minimization a computationally efficient learning algorithm for the Principal Component Analysis(PCA) is derived. The dual learning rate parameters are adaptively introduced to make the proposed algorithm providing the capability of the fast convergence and high accuracy for extracting all the principal components. It is shown that all the information needed for PCA can be completely represented by the unnormalized weight vector which is updated based only on the corresponding neuron input-output product. The convergence performance of the proposed algorithm is briefly analyzed.The relation between Oja’s rule and the least squares learning rule is also established. Finally, a simulation example is given to illustrate the effectiveness of this algorithm for PCA. 展开更多
关键词 NEURAL networks Principal component analysis Auto-association RECURSIVE least squares(RLS) learning rule
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pLoc_Deep-mEuk: Predict Subcellular Localization of Eukaryotic Proteins by Deep Learning 被引量:3
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作者 Yutao Shao Kuo-Chen Chou 《Natural Science》 2020年第6期400-428,共29页
<span style="font-family:Verdana;"> <p class="MsoNormal"> <span lang="EN-US" style="" color:black;"="">Recently, the life of worldwide human bei... <span style="font-family:Verdana;"> <p class="MsoNormal"> <span lang="EN-US" style="" color:black;"="">Recently, the life of worldwide human beings has been endangering by the spreading of </span><span style="font-variant-ligatures:normal;font-variant-caps:normal;orphans:2;text-align:start;widows:2;-webkit-text-stroke-width:0px;text-decoration-style:initial;text-decoration-color:initial;word-spacing:0px;">pneu</span><span style="font-variant-ligatures:normal;font-variant-caps:normal;orphans:2;text-align:start;widows:2;-webkit-text-stroke-width:0px;text-decoration-style:initial;text-decoration-color:initial;word-spacing:0px;">- </span><span style="font-variant-ligatures:normal;font-variant-caps:normal;orphans:2;text-align:start;widows:2;-webkit-text-stroke-width:0px;text-decoration-style:initial;text-decoration-color:initial;word-spacing:0px;">monia</span><span style="font-variant-ligatures:normal;font-variant-caps:normal;orphans:2;text-align:start;widows:2;-webkit-text-stroke-width:0px;text-decoration-style:initial;text-decoration-color:initial;word-spacing:0px;">-</span><span style="font-variant-ligatures:normal;font-variant-caps:normal;orphans:2;text-align:start;widows:2;-webkit-text-stroke-width:0px;text-decoration-style:initial;text-decoration-color:initial;word-spacing:0px;">causing virus, such as Coronavirus, COVID-19, and H1N1. To develop effective </span><span style="font-variant-ligatures:normal;font-variant-caps:normal;orphans:2;text-align:start;widows:2;-webkit-text-stroke-width:0px;text-decoration-style:initial;text-decoration-color:initial;word-spacing:0px;">drugs against Coronavirus, knowledge of protein subcellular localization is prerequisite. In 2019, a predictor called “pLoc_bal-mEuk” was developed for identifying the subcellular localization of eukaryotic proteins. Its predicted results are significantly better than its counterparts, particularly for those proteins that may simultaneously occur or move between two or more subcellular location sites. However, more efforts are definitely needed to further improve its power since pLoc_bal-mEuk was still not trained by a “deep learning”, a very powerful technique developed recently. The present study was devoted to incorporating the “deep</span><span style="font-variant-ligatures:normal;font-variant-caps:normal;orphans:2;text-align:start;widows:2;-webkit-text-stroke-width:0px;text-decoration-style:initial;text-decoration-color:initial;word-spacing:0px;">- </span><span style="font-variant-ligatures:normal;font-variant-caps:normal;orphans:2;text-align:start;widows:2;-webkit-text-stroke-width:0px;text-decoration-style:initial;text-decoration-color:initial;word-spacing:0px;">learning” technique and develop</span><span style="font-variant-ligatures:normal;font-variant-caps:normal;orphans:2;text-align:start;widows:2;-webkit-text-stroke-width:0px;text-decoration-style:initial;text-decoration-color:initial;word-spacing:0px;">ed</span><span style="font-variant-ligatures:normal;font-variant-caps:normal;orphans:2;text-align:start;widows:2;-webkit-text-stroke-width:0px;text-decoration-style:initial;text-decoration-color:initial;word-spacing:0px;"> a new predictor called “pLoc_Deep-mEuk”. The global absolute true rate achieved by the new predictor is over 81% and its local accuracy is over 90%. Both are overwhelmingly superior to its counterparts. Moreover, a user-friendly web-</span><span style="font-variant-ligatures:normal;font-variant-caps:normal;orphans:2;text-align:start;widows:2;-webkit-text-stroke-width:0px;text-decoration-style:initial;text-decoration-color:initial;word-spacing:0px;"> </span><span style="font-variant-ligatures:normal;font-variant-caps:normal;orphans:2;text-align:start;widows:2;-webkit-text-stroke-width:0px;text-decoration-style:initial;text-decoration-color:initial;word-spacing:0px;">server for the new predictor has been well established at <a href="http://www.jci-bioinfo.cn/pLoc_Deep-mEuk/">http://www.jci-bioinfo.cn/pLoc_Deep-mEuk/</a>, by which the majority of experimental scientists can easily get their desired data.</span> </p> </span> 展开更多
关键词 CORONAVIRUS Multi-Label System Eukaryotic Proteins Deep learning Five-Steps rule PseAAC
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pLoc_Deep-mHum: Predict Subcellular Localization of Human Proteins by Deep Learning 被引量:3
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作者 Yu-Tao Shao Xin-Xin Liu +1 位作者 Zhe Lu Kuo-Chen Chou 《Natural Science》 2020年第7期526-551,共26页
Recently, the life of human beings around the entire world has been endangering by the spreading of pneumonia-causing virus, such as Coronavirus, COVID-19, and H1N1. To develop effective drugs against Coronavirus, kno... Recently, the life of human beings around the entire world has been endangering by the spreading of pneumonia-causing virus, such as Coronavirus, COVID-19, and H1N1. To develop effective drugs against Coronavirus, knowledge of protein subcellular localization is indispensable. In 2019, a predictor called “pLoc_bal-mHum” was developed for identifying the subcellular localization of human proteins. Its predicted results are significantly better than its counterparts, particularly for those proteins that may simultaneously occur or move between two or more subcellular location sites. However, more efforts are definitely needed to further improve its power since pLoc_bal-mHum was still not trained by a “deep learning”, a very powerful technique developed recently. The present study was devoted to incorporate the “deep-learning” technique and develop a new predictor called “pLoc_Deep-mHum”. The global absolute true rate achieved by the new predictor is over 81% and its local accuracy is over 90%. Both are overwhelmingly superior to its counterparts. Moreover, a user-friendly web-server for the new predictor has been well established at http://www.jci-bioinfo.cn/pLoc_Deep-mHum/, which will become a very useful tool for fighting pandemic coronavirus and save the mankind of this planet. 展开更多
关键词 CORONAVIRUS Multi-Label System Human Proteins Deep learning Five-Steps rule PseAAC
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pLoc_Deep-mVirus: A CNN Model for Predicting Subcellular Localization of Virus Proteins by Deep Learning 被引量:3
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作者 Yutao Shao Kuo-Chen Chou 《Natural Science》 2020年第6期388-399,共12页
<p class="MsoNormal"> <span lang="EN-US" style="" color:black;"="">The recent worldwide spreading of pneumonia-causing virus, such as Coronavirus, </span>... <p class="MsoNormal"> <span lang="EN-US" style="" color:black;"="">The recent worldwide spreading of pneumonia-causing virus, such as Coronavirus, </span><span "="" style="font-variant-ligatures:normal;font-variant-caps:normal;orphans:2;text-align:start;widows:2;-webkit-text-stroke-width:0px;text-decoration-style:initial;text-decoration-color:initial;word-spacing:0px;">COVID-19, and H1N1, has been endangering the life of human beings all around the world. In order to really understand the biological process within a cell level and provide useful clues to develop antiviral drugs, information of virus protein subcellular localization is vitally important. In view of this, a CNN based virus protein subcellular localization predictor called “pLoc_Deep-mVirus” was developed. The predictor is particularly useful in dealing with the multi-sites systems in which some proteins may simultaneously occur in two or more different organelles that are the current focus of pharmaceutical industry. The global absolute true rate achieved by the new predictor is over 97% and its local accuracy is over 98%. Both are transcending other existing state-of-the-art predictors significantly. It has not escaped our notice that the deep-learning treatment can be used to deal with many other biological systems as well. To maximize the convenience for most experimental scientists, a user-friendly web-server for the new predictor has been established at <a href="http://www.jci-bioinfo.cn/pLoc_Deep-mVirus/">http://www.jci-bioinfo.cn/pLoc_Deep-mVirus/</a>.</span> </p> 展开更多
关键词 CORONAVIRUS Virus Proteins Multi-Label System Deep learning Five-Steps rule PseAAC
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pLoc_Deep-mPlant: Predict Subcellular Localization of Plant Proteins by Deep Learning 被引量:2
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作者 Yu-Tao Shao Xin-Xin Liu +1 位作者 Zhe Lu Kuo-Chen Chou 《Natural Science》 2020年第5期237-247,共11页
Current coronavirus pandemic has endangered mankind life. The reported cases are increasing exponentially. Information of plant protein subcellular localization can provide useful clues to develop antiviral drugs. To ... Current coronavirus pandemic has endangered mankind life. The reported cases are increasing exponentially. Information of plant protein subcellular localization can provide useful clues to develop antiviral drugs. To cope with such a catastrophe, a CNN based plant protein subcellular localization predictor called “pLoc_Deep-mPlant” was developed. The predictor is particularly useful in dealing with the multi-sites systems in which some proteins may simultaneously occur in two or more different organelles that are the current focus of pharmaceutical industry. The global absolute true rate achieved by the new predictor is over 95% and its local accuracy is about 90%?-?100%. Both have substantially exceeded the?other existing state-of-the-art predictors. To maximize the convenience for most?experimental scientists, a user-friendly web-server for the new predictor has been established?at?http://www.jci-bioinfo.cn/pLoc_Deep-mPlant/, by which the majority of experimental?scientists can easily obtain their desired data without the need to go through the?mathematical details. 展开更多
关键词 PANDEMIC CORONAVIRUS MULTI-LABEL System Plant Proteins learning at Deeper Level Five-Steps rule PseAAC
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pLoc_Deep-mGneg: Predict Subcellular Localization of Gram Negative Bacterial Proteins by Deep Learning 被引量:2
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作者 Xin-Xin Liu Kuo-Chen Chou 《Advances in Bioscience and Biotechnology》 2020年第5期141-152,共12页
The recent worldwide spreading of pneumonia-causing virus, such as Coronavirus, COVID-19, and H1N1, has been endangering the life of human beings all around the world. In order to really understand the biological proc... The recent worldwide spreading of pneumonia-causing virus, such as Coronavirus, COVID-19, and H1N1, has been endangering the life of human beings all around the world. In order to really understand the biological process within a cell level and provide useful clues to develop antiviral drugs, information of Gram negative bacterial protein subcellular localization is vitally important. In view of this, a CNN based protein subcellular localization predictor called “pLoc_Deep-mGnet” was developed. The predictor is particularly useful in dealing with the multi-sites systems in which some proteins may simultaneously occur in two or more different organelles that are the current focus of pharmaceutical industry. The global absolute true rate achieved by the new predictor is over 98% and its local accuracy is around 94% - 100%. Both are transcending other existing state-of-the-art predictors significantly. To maximize the convenience for most experimental scientists, a user-friendly web-server for the new predictor has been established at http://www.jci-bioinfo.cn/pLoc_Deep-mGneg/, which will become a very useful tool for fighting pandemic coronavirus and save the mankind of this planet. 展开更多
关键词 PANDEMIC CORONAVIRUS MULTI-LABEL System GRAM Negative BACTERIAL Proteins learning at Deeper Level Five-Steps rule PseAAC
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iATC_Deep-mISF: A Multi-Label Classifier for Predicting the Classes of Anatomical Therapeutic Chemicals by Deep Learning 被引量:1
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作者 Zhe Lu Kuo-Chen Chou 《Advances in Bioscience and Biotechnology》 2020年第5期153-159,共7页
The recent worldwide spreading of pneumonia-causing virus, such as Coronavirus, COVID-19, and H1N1, has been endangering the life of human beings all around the world. To provide useful clues for developing antiviral ... The recent worldwide spreading of pneumonia-causing virus, such as Coronavirus, COVID-19, and H1N1, has been endangering the life of human beings all around the world. To provide useful clues for developing antiviral drugs, information of anatomical therapeutic chemicals is vitally important. In view of this, a CNN based predictor called “iATC_Deep-mISF” has been developed. The predictor is particularly useful in dealing with the multi-label systems in which some chemicals may occur in two or more different classes. To maximize the convenience for most experimental scientists, a user-friendly web-server for the new predictor has been established at http://www.jci-bioinfo.cn/iATC_Deep-mISF/, which will become a very powerful tool for developing effective drugs to fight pandemic coronavirus and save the mankind of this planet. 展开更多
关键词 Pandemic CORONAVIRUS MULTI-LABEL System ANATOMICAL THERAPEUTIC CHEMICALS learning at Deeper Level Five-Steps rule
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