Background: The present study was conducted to examine the association between various coronary risk factors and clinical parameters, with special emphasis on ankle-brachial index, in predicting the severity and compl...Background: The present study was conducted to examine the association between various coronary risk factors and clinical parameters, with special emphasis on ankle-brachial index, in predicting the severity and complexity of coronary artery disease. Methods: Patients diagnosed with coronary artery disease at our hospital between September-2012 and December-2014 were examined in this study. Selected patients were screened for cardiovascular risk factors including diabetes, hypertension, smoking, and alcohol habits as well as for clinical parameters including body-mass index, waist-hip ratio, ankle-brachial index, and ejection fraction. All patients underwent coronary angiography and were evaluated for severity of coronary artery disease (based on number of vessels involved) and complexity of coronary angiographic lesions (measured by computer-assisted Syntax score calculator). The collected data were analyzed to determine the role of cardiovascular risk factors and clinical parameters as predictors of complexity and severity of coronary artery disease. Results: A total of 211 patients (mean age: 54.64 ± 9.9 years;81% males) with coronary artery disease were analyzed. Findings revealed that diabetes mellitus (p < 0.001), hypertension (p < 0.001), smoking habits (p = 0.036), and low ankle-brachial index (p < 0.001) were independent predictors of complex coronary artery disease as measured by Syntax score. Significant associations were also evident between severity of coronary artery disease and diabetes mellitus (p < 0.001), hypertension (p < 0.001), and ankle-brachial index (p < 0.001). Conversely, other cardiovascular risk factors including body-mass index, alcohol habits, wait-hip ratio, and ejection fraction did not exhibit significant associations with severity and complexity of coronary artery. Conclusions: The early diagnosis of coronary artery can be predicated by evaluating diabetes, hypertension, and smoking habits in patients presenting with acute coronary syndrome. In addition, ankle-brachial index can be used as an effective non-invasive bed-side tool, as an alternative to Syntax score, in predicting the severity and complexity of coronary artery disease.展开更多
目的研究单侧腰麻轻比重大容量配方在高龄患者髋部手术中的应用价值。方法选取2019年1月至2021年12月行髋部手术的96例高龄患者为研究对象,采用随机数字表法,按照1∶1配比原则将患者分为对照组和研究组,每组48例。髋部手术中,对照组采...目的研究单侧腰麻轻比重大容量配方在高龄患者髋部手术中的应用价值。方法选取2019年1月至2021年12月行髋部手术的96例高龄患者为研究对象,采用随机数字表法,按照1∶1配比原则将患者分为对照组和研究组,每组48例。髋部手术中,对照组采用全麻方法,研究组采用单侧腰麻轻比重大容量配方,比较2组麻醉情况、不同时间段的血流动力学、术后双下肢肌力恢复时间、自主排尿恢复时间以及不良反应发生率。结果对照组和研究组感觉阻滞、运动阻滞的起效时间和持续时间比较差异无统计学意义(P>0.05)。麻醉后10 min、30 min 2组平均脉动压(MVP)、心率(HR)较麻醉前降低(P<0.05),但2组比较差异无统计学意义(P>0.05);术毕2 min,2组MVP、HR比较差异无统计学意义(P>0.05)。研究组术后双下肢肌力恢复时间、自主排尿恢复时间均长于对照组(P<0.05)。结论在高龄患者髋部手术中采用单侧腰麻轻比重大容量配方,能获得与全麻相近的麻醉效果,维持血流动力学稳定,降低不良反应发生率,但患者的下肢肌力恢复较慢。展开更多
文摘Background: The present study was conducted to examine the association between various coronary risk factors and clinical parameters, with special emphasis on ankle-brachial index, in predicting the severity and complexity of coronary artery disease. Methods: Patients diagnosed with coronary artery disease at our hospital between September-2012 and December-2014 were examined in this study. Selected patients were screened for cardiovascular risk factors including diabetes, hypertension, smoking, and alcohol habits as well as for clinical parameters including body-mass index, waist-hip ratio, ankle-brachial index, and ejection fraction. All patients underwent coronary angiography and were evaluated for severity of coronary artery disease (based on number of vessels involved) and complexity of coronary angiographic lesions (measured by computer-assisted Syntax score calculator). The collected data were analyzed to determine the role of cardiovascular risk factors and clinical parameters as predictors of complexity and severity of coronary artery disease. Results: A total of 211 patients (mean age: 54.64 ± 9.9 years;81% males) with coronary artery disease were analyzed. Findings revealed that diabetes mellitus (p < 0.001), hypertension (p < 0.001), smoking habits (p = 0.036), and low ankle-brachial index (p < 0.001) were independent predictors of complex coronary artery disease as measured by Syntax score. Significant associations were also evident between severity of coronary artery disease and diabetes mellitus (p < 0.001), hypertension (p < 0.001), and ankle-brachial index (p < 0.001). Conversely, other cardiovascular risk factors including body-mass index, alcohol habits, wait-hip ratio, and ejection fraction did not exhibit significant associations with severity and complexity of coronary artery. Conclusions: The early diagnosis of coronary artery can be predicated by evaluating diabetes, hypertension, and smoking habits in patients presenting with acute coronary syndrome. In addition, ankle-brachial index can be used as an effective non-invasive bed-side tool, as an alternative to Syntax score, in predicting the severity and complexity of coronary artery disease.
文摘目的研究单侧腰麻轻比重大容量配方在高龄患者髋部手术中的应用价值。方法选取2019年1月至2021年12月行髋部手术的96例高龄患者为研究对象,采用随机数字表法,按照1∶1配比原则将患者分为对照组和研究组,每组48例。髋部手术中,对照组采用全麻方法,研究组采用单侧腰麻轻比重大容量配方,比较2组麻醉情况、不同时间段的血流动力学、术后双下肢肌力恢复时间、自主排尿恢复时间以及不良反应发生率。结果对照组和研究组感觉阻滞、运动阻滞的起效时间和持续时间比较差异无统计学意义(P>0.05)。麻醉后10 min、30 min 2组平均脉动压(MVP)、心率(HR)较麻醉前降低(P<0.05),但2组比较差异无统计学意义(P>0.05);术毕2 min,2组MVP、HR比较差异无统计学意义(P>0.05)。研究组术后双下肢肌力恢复时间、自主排尿恢复时间均长于对照组(P<0.05)。结论在高龄患者髋部手术中采用单侧腰麻轻比重大容量配方,能获得与全麻相近的麻醉效果,维持血流动力学稳定,降低不良反应发生率,但患者的下肢肌力恢复较慢。