Seasonality of the Interaction between Convection over the Western Pacific and General Circulation in the Northern Hemisphere

The seasonality of the interaction between convection over the western Pacific and general circulation in the Northern Hemisphere (NH) is analyzed in the present paper with singular value decomposition (SVD) and empirical orthogonal function (EOF) analysis approaches, based on 500 hPa monthly mean geopotential height data and high-cloud amount data. The analyses demonstrate that coupled dominant patterns in the interaction between the convection over the western Pacific and the general circulation in NH are different in various seasons. In spring, the convection over the western Pacific is closely related with the western Atlantic (WA) and North Pacific (NP) like patterns of the general circulation in NH, and some associations between the WA and NP like patterns and the El Ni o /Southern Oscillation (ENSO) cycle are also existed. The Pacific Japan (PJ) pattern is the dominant pattern in the interaction between the interannual variabilities of the convection over the western Pacific and the general circulation in NH summer. The WA like pattern and 3-4 year period oscillation are also relatively obvious for the summer case. In autumn, the convection over the western Pacific is closely linked with the Eurasian (EU) like pattern and the Atlantic oscillation in the general circulation in NH, it is suggested that in autumn the variation of convective activity over the western Pacific is largely affected by the general circulation anomaly (cold air from high latitudes ) through EU like teleconnection pattern. Abrupt change happened by the end of 1980′s in the autumn interaction. The strong interaction between the western Pacific (WP) and EU like patterns in the general circulation in NH and the convection over the western Pacific and a linear trend of increasing of this interaction are also suggested in winter. It is also demonstrated that the interaction in summer and winter is stronger than in the transition seasons (spring and autumn).

Combined impact of in-phase and out-of-phase variation between the northern East Asian low and western North Pacific subtropical high on East Asian summer rainfall

East Asian summer rainfall is affected by both the continental northern East Asian low （NEAL） and the western North Pacific subtropical high （WNPSH） in the lower troposphere. This study investigates the joint effect of the two circulation factors on East Asian summer rainfall. It is found that the rainfall in East Asia behaves differently in the years with in-phase and out-of-phase variation between the NEAL and WNPSH. When the NEAL and WNPSH vary in phase, i.e. when they are both stronger, the rainfall anomaly shows a dipole pattern in East Asia and displays opposite changes between north and south of 30°N. When the two circulation factors vary out of phase, the rainfall anomaly is concentrated in the Yangtze River valley.

Intensified Impact of Northern Tropical Atlantic SST on Tropical Cyclogenesis Frequency over the Western North Pacific after the Late 1980s

Previous studies suggest that spring SST anomalies over the northern tropical Atlantic（NTA） affect the tropical cyclone（TC） activity over the western North Pacific（WNP） in the following summer and fall. The present study reveals that the connection between spring NTA SST and following summer–fall WNP TC genesis frequency is not stationary. The influence of spring NTA SST on following summer–fall WNP TC genesis frequency is weak and insignificant before, but strong and significant after, the late 1980 s. Before the late 1980 s, the NTA SST anomaly-induced SST anomalies in the tropical central Pacific are weak, and the response of atmospheric circulation over the WNP is not strong. As a result, the connection between spring NTA SST and following summer–fall WNP TC genesis frequency is insignificant in the former period. In contrast,after the late 1980 s, NTA SST anomalies induce pronounced tropical central Pacific SST anomalies through an Atlantic–Pacific teleconnection. Tropical central Pacific SST anomalies further induce favorable conditions for WNP TC genesis,including vertical motion, mid-level relative humidity, and vertical zonal wind shear. Hence, the connection between NTA SST and WNP TC genesis frequency is significant in the recent period. Further analysis shows that the interdecadal change in the connection between spring NTA SST and following summer–fall WNP TC genesis frequency may be related to the climatological SST change over the NTA region.

Influence of climatic warming in the Southern and Northern Hemi-sphere on the tropical cyclone over the western North Pacific Ocean

Based on analyzing the surface air temperature series in the Southern and Northern Hemisphere and the tropical cyclone (TC) over the western North Pacific Ocean, the relationships between climatic warming and the frequency and intensity of tropical cyclone are investigated. The results showed that with the climatic warming in both hemispheres, the frequency of the tropical cyclone over the western North Pacific Ocean reduces and its intensity weakens simultaneously. A possible explanation might be that the cold air invasion from the Southern Hemisphere weakens due to global warming.

Preparation of monoclonal antibody against human KIAA0100 protein and Northern blot analysis of human KIAA0100 gene

Monoclonal antibodies(MAbs) are important tools for the study of proteins′ function and structure. But there has been no report on the preparation of MAbs against human KIAA0100 protein up to date. Here, first, we generated the mouse MAb against human KIAA0100 protein using purified recombinant 6×Histidinc(6×His)-tagged human KIAA0100 protein segment(1557–2234) as an antigen; then, the m RNA expression of human KIAA0100 gene was detected in U937 cells using Northern blot analysis. The results showed that the mouse MAb against human KIAA0100 protein could sensitively recognize the human KIAA0100 protein using Western blot analysis and immunocytochemistry analysis. Besides, Western blot analysis revealed that human KIAA0100 gene possibly encoded two different protein products(254 k Da and < 250 k Da) in U937 cells. Moreover,Northern blot analysis confirmed that human KIAA0100 gene might produced two different m RNA products(6000–10000 bp and 5000–6000 bp) in U937 cells. The results provide a basis for large-scale production of the MAb against human KIAA0100 protein, which will be useful for the study of human KIAA0100 protein′s function/structure and MAb-targeted drugs in the future.

Attenuation characteristics of ground motions in northern China

Four recently developed attenuation models are calibrated by using a very limited amount of strong motion data recorded in China.The research shows that the attenuation characteristics of the earthquake shaking in northern China are similar to those in the western US.The supporting evidence includes Q factors,preliminary results of kappa values,stress drop, shear wave velocity profile in the shallow earth crust,areas enclosed by the isoseismals of Modified Mercalli Intensity V.From these comparison,s of different attenuation models,it is recommended that the Crouse and McGuire spectral attenuation model could possibly be used for northern China.

Intercomparison of the Impacts of Four Summer Teleconnections over Eurasia on East Asian Rainfall

East Asian summer climate is strongly affected by extratropical circulation disturbances.In this study,impacts of four atmospheric teleconnections over Eurasia on East Asian summer rainfall are investigated using National Centers for Environmental Prediction/National Center for Atmospheric Research （NCEP/NCAR） reanalysis data and Climatic Research Unit （CRU） land precipitation data during 1979-2009.The four teleconnections include the Scandinavian （SCA）,the Polar/Eurasian （PEU）,the East Atlantic/Western Russian （EAWR）,and the circumglobal teleconnection （CGT）.Moreover,the related changes of lower-tropospheric circulation are explored,specifically,the low pressure over northern East Asia （NEAL） and the subtropical high over the western North Pacific （WNPSH）.The results presented are in the positive phase.The PEU and SCA induce significant negative anomalies in North China rainfall （NCR）,while the CGT induces significant positive anomalies.In the past three decades,the PEU and SCA explain more than 20％ of the variance in NCR,twice that explained by the CGT,suggesting a more important role of the former two teleconnections in NCR variation than the latter one.Meanwhile,the PEU and SCA reduce rainfall in Northeast China and South Korea,respectively,and the CGT enhances rainfall in Japan.The rainfall responses are attributed to the SCA-induced northward shift of the NEAL,and PEU-induced northward shift and weakening of the NEAL,respectively.For the CGT,the dipole pattern of rainfall anomalies between North China and Japan is affected by both westward extension of the NEAL and northwestward expansion of the WNPSH.In addition,the EAWR leads to an increase of sporadic rainfall in South China as a result of the eastward retreat of the WNPSH.

RNA interference-mediated gene silencing of vascular endothelial growth factor in colon cancer cells

AIM： TO inhibit the expression of vascular endothelial growth factor （VEGF） in colon cancer cell line by RNA interference （RNAi）.METHODS： Followed the service of E-RNAi, we designed and constructed two kinds of shRNA expression vectors aiming at the VEGF gene, then transfected them into colon cancer HT29 cells by lipofectamineTM 2000. The level of VEGF mRNA was investigated by RT-PCR and Northern blotting. The protein expression of VEGF was observed by immunofluoresence staining and Western blotting.RESULTS： We got two kinds of VEGF specific shRNA expression vectors which could efficiently inhibit the expression of VEGF in HT29 cells. RT-PCR, Northern blotting, immunofluoresence staining and Western blotting showed that inhibition rate for VEGF expression was up to 42%, 89%, 73% and 82%, respectively.CONCLUSION： The expression of VEGF can be inhibited by RNA interference in HT29 cells.

Comparison of the Palaeomagnetic Parameters of Non-Marine Jurassic-Cretaceous Boundary Sediments in Dorset(SW England),Hebei and Liaoning(NE China)—A Preliminary Study

The Purbeck beds in Dorset, the Tuchengzi Formation in western Liaoning Liaoning Province or the Houcheng Formation in northern Hebei Province are non-marine Jurassic/Cretaceous (J/K) boundary sequences. A Czech-China Inter-Governmental S&T Cooperation Project has been carried out to search for the non-marine J/K boundary in northern China and making international correlation with the Purbeck beds in southern England. The combination of palaeomagnetism and biostratigraphy in northern China and southern England localities proves that these distant places had similar climatic conditions and the same fauna during the Late Jurassic and Early Cretaceous. A preliminary joint research has shown a fruitful result in searching for the non-marine J/K boundary in northern China.

沁水盆地南部中深部煤层气储层特征及开发技术对策

为了实现沁水盆地南部中深部煤层气高效开发,以郑庄北-沁南西区块为研究对象,基于参数井取心分析测试、注入/压降测试、地应力循环测试结果和大量动静态数据,通过与浅部对比,阐述了中深部煤储层特征,分析了从浅部到中深部煤层直井压裂和水平井分段压裂两种开发技术的改进,进而提出了中深部煤层气主体开发技术。结果表明,郑庄北-沁南西区块3号煤平均埋深1200 m左右,为中深部煤层气储层。随着埋深增加,研究区含气量和吸附时间均先增加后降低,含气量和吸附时间峰值分别位于埋深1100~1200 m和800~1000 m;随着埋深增加,研究区地应力场类型发生了2次转换,埋深小于600 m时,为逆断层型地应力场类型,水力压裂易形成水平缝,利于造长缝;埋深大于1000 m时为走滑断层型地应力场类型,水力压裂易形成垂直缝,裂缝延伸较短;埋深为600~1000 m时,地应力场由逆断层型向走滑断层型转换阶段,水力压裂形成的裂缝系统较为复杂。与浅层相比,中深部储层含气量、解吸效率和应力场发生明显转变。随着埋深增加,无论是直井(定向井)还是水平井,均应采用更大的压裂规模才能获得较好的效果。对于直井,埋深大于800 m后,压裂液量达到1500 m^(3)以上、排量12~15 m^(3)/min以上、砂比10%~14%以上,单井日产气量可以达到1000 m^(3)以上;对于水平井,埋深大于800 m后,压裂段间距控制在70~90 m以下,单段液量、砂量分别达到2000、150 m^(3)以上,排量达到15 m^(3)/min以上开发效果较好,单井产量突破18000 m^(3)。随着埋深增加,水平井开发方式明显优于直井,以二开全通径水平井井型结构、优质层段识别技术和大规模、大排量缝网压裂为核心的水平井开发方式是适用于沁水盆地南部中深部煤层气高效开发的主体工艺技术。

陕北晋西汉画像石主神图像研究

本文通过对陕北晋西汉代主神画像发展脉络的梳理,认为该区域汉代画像中最早出现的主神是伏羲、女娲,随后在西王母信仰传入且没有大范围流行之前,鸡首、牛首人身神人作为主要神仙端坐于玄圃之上,再后西王母成为该区域汉画像中最重要的主神形象。就西王母画像组合中的男性仙人身份进行解析,可见雨师、仙官、子路和东王公。

蒙正和长篇小说《蝴蝶谷之恋》蕴含的文化自信

蒙正和长篇小说《蝴蝶谷之恋》以滇缅抗战为背景,通过讲述一个美国飞行员在中国的遭际,为读者呈现一个典型的中国故事。这个中国故事蕴含了21世纪20年代中国人的文化自信,主要表现在人物塑造彰显文化自信、民间生活描写寄寓文化自信、“外来者”形象凸显文化自信三方面。小说为读者建构了一个讲述中国故事、彰显文化自信的意义空间。

戎与狄--西北地区东周戎狄遗存的探索历程与思考

西北地区的东周戎狄族群,在文献与考古学遗存上都表现出“西戎”与“北狄”的双重特征。21世纪前,“寺洼文化—毛家坪B组遗存”序列与甘宁地区的北方系遗存都被认为是东周西戎,但三者间的关系尚不清楚。21世纪以来,伴随新发现的推进,学界针对三种遗存与东周西戎的关系提出多种认识,其中虽有共识,但仍存在关键分歧。西北地区的东周戎狄遗存应打破单一分类,充实材料,扩大视野,以多元视角阐释遗存与人群的多样性。

新出隋《施睿墓志》考

2021年,隋《施睿墓志》出土于西安市长安区郭杜樱花广场基建工地内。志主施睿为南北朝时期北迁之南士。南北朝时期有大量的南人北迁,其自身的文化优势得以在关中地区迅速发挥出来,填补了关陇地区的文化缺失。

粤东西北应用型高校产教融合共生系统构建:理论逻辑、现实问题与行动路径

随着国家及各省市产教融合建设试点实施方案及地方本科高校应用型转型的稳步推进,地方与高校产教融合发展趋势不断增强,双方共生关系日益显现。在共生理论视域下,粤东西北应用型高校产教融合通过共生单元、共生模式和共生环境构成共生系统,但共生单元未激活、共生模式动力不足、共生环境不友好是制约当前粤东西北应用型高校产教融合成效的现实问题。针对当前现状,从优化共生单元、强化共生模式、改善共生环境三方面出发,提出粤东西北应用型高校构建产教融合共生系统的行动路径。

西辽河文明视域下的北疆文化内涵挖掘与品牌打造

为学习贯彻习近平文化思想,内蒙古自治区党委打造了“北疆文化”品牌,这不仅是助力内蒙古文化事业和文化产业高质量发展的重要抓手,更是建设中华民族共有精神家园、铸牢中华民族共同体意识的重要路径。“中华文明探源工程”明确将西辽河文明与黄河文明、长江文明一同列为中华文明的三大源头。西辽河文明植根于悠久的中华文脉中,在建设中华民族现代文明历程中体现出了地区精神和时代特征。西辽河文化赓续源浚流长的文脉,秉承中华文明连续性;西辽河文化发扬守正进取的精神,展现中华文明创新性;西辽河文化见证多元一体的形成,突出中华文明统一性;西辽河文化具有兼容并蓄的特点,彰显中华文明包容性;西辽河文化坚持交流互鉴的理念,体现中华文明和平性。

Devonian ichnofossils and their environmental significance of northern belt of Western Qinling Mountains

It is beheved that the Shujiaba Formation belongs to a series of thick turbidites. 20 ichnogenera have been found in the formation, of which 14 genera were found in the Devonian System of China for the first time The ichnogenera are mostly of typical deep-water ones and belong to the Nereites ichnofacies A detailed study of morphology and behaviour of the trace fossils indicates that the Shujiaba Formation was deposited in a bathyal-abyssal environment.

Constraints on the age of the Tuchengzi Formation by LA-ICP-MS dating in northern Hebei-western Liaoning, China

Accurately determining the age of the Tuchengzi Formation has direct influence on confirming the boundary between the Jurassic and the Cretaceous systems in northern Hebei-western Liaoning, and on related geological problems in China. However, the Tuchengzi Formation mainly consists of sedi-mentary rocks, with a poor fossil record and especially lack of index fossils. The Tuchengzi Formation is also lack of the type of volcanic rocks that can provide an isotopic age. Therefore, the age of the Tuchengzi Formation has been uncertain. Based on our systematic dating of the tuff interbedded in the Tuchengzi Formation of Chengde and Jinlingsi-Yangshan basins in northern Hebei-western Liaoning, combined with the dating results of previous researchers, here we suggest that the age range of the Tuchengzi Formation in northern Hebei-western Liaoning is from 147 Ma to 136 Ma. It implied that the Tuchengzi Formation was mainly formed in the Early Cretaceous.

Overexpression of heme oxygenase-1 protects smooth muscle cells against oxidative injury and inhibits cell proliferation

To investigate whether the expression of exogenous heme oxygenase-1 (HO-1) gene within vascular smooth muscle cells (VSMC) could protect the cells from free radical attack and inhibit cell proliferation, we established an in vitro transfection of human HO-1 gene into rat VSMC mediated by a retroviral vector. The results showed that the profound expression of HO-1 protein as well as HO activity was 1.8- and 2.0-fold increased respectively in the transfected cells compared to the non-transfected ones. The treatment of VSMC with different concentrations of H2O2 led to the remarkable cell damage as indicated by survival rate and LDH leakage. However, the resistance of the HO-1 transfected VSMC against H2O2 was significantly raised. This protective effect was dramatically diminished when the transfected VSMC were pretreated with ZnPP-IX, a specific inhibitor of HO, for 24 h. In addition, we found that the growth potential of the transfected cells was significantly inhibited directly by increased activity of HO-1, and this effect might be related to decreased phosphorylation of MAPK. These results suggest that the overexpression of introduced hHO-1 is potentially able to reduce the risk factors of atherosclerosis, partially due to its cellular protection against oxidative injury and to its inhibitory effect on cellular proliferation.