Understanding the composition and contents of carotenoids in various soybean seed accessions is important for their nutritional assessment.This study investigated the variability in the concentrations of carotenoids a...Understanding the composition and contents of carotenoids in various soybean seed accessions is important for their nutritional assessment.This study investigated the variability in the concentrations of carotenoids and chlorophylls and revealed their associations with other nutritional quality traits in a genetically diverse set of Chinese soybean accessions comprised of cultivars and landraces.Genotype,planting year,accession type,seed cotyledon color,and ecoregion of origin significantly influenced the accumulation of carotenoids and chlorophylls.The mean total carotenoid content was in the range of 8.15–14.72μg g–1 across the ecoregions.The total carotenoid content was 1.2-fold higher in the landraces than in the cultivars.Soybeans with green cotyledons had higher contents of carotenoids and chlorophylls than those with yellow cotyledons.Remarkably,lutein was the most abundant carotenoid in all the germplasms,ranging from 1.35–37.44μg g–1.Carotenoids and chlorophylls showed significant correlations with other quality traits,which will help to set breeding strategies for enhancing soybean carotenoids without affecting the other components.Collectively,our results demonstrate that carotenoids are adequately accumulated in soybean seeds,however,they are strongly influenced by genetic factors,accession type,and germplasm origin.We identified novel germplasms with the highest total carotenoid contents across the various ecoregions of China that could serve as the genetic materials for soybean carotenoid breeding programs,and thereby as the raw materials for food sectors,pharmaceuticals,and the cosmetic industry.展开更多
Objective To introduce the accession procedure and evaluation of PIC/S,and help relevant departments in China to understand the requirements of PIC/S in detail,and to promote the process of China’s entry into PIC/S.M...Objective To introduce the accession procedure and evaluation of PIC/S,and help relevant departments in China to understand the requirements of PIC/S in detail,and to promote the process of China’s entry into PIC/S.Methods The procedures and steps of joining PIC/S,the evaluation process of PIC/S,and the experience of several countries in joining PIC/S were introduced and analyzed,which could help the relevant personnel in China understand the specific contents.Results and Conclusion According to the requirements of PIC/S,it is necessary to establish a unified GMP quality management system.展开更多
The Ministerial Conference Decision of 10 NOV.2001 Having regard to paragraph 2 of Article Ⅻ and paragraph 1 of Article Ⅸ of the Marrakesh Agreement Establishing the World Trade Organization, and the Decision—Makin...The Ministerial Conference Decision of 10 NOV.2001 Having regard to paragraph 2 of Article Ⅻ and paragraph 1 of Article Ⅸ of the Marrakesh Agreement Establishing the World Trade Organization, and the Decision—Making Procedures under Articles Ⅸ and Ⅻ of the Marrakesh Agreement Establishing the World Trade Organization agreed by the General Council (WT/L/93). Taking note of the application 0f the People's Republic of China for accession to the Marrakesh Agreement Establishing the World Trade Organiza-展开更多
The terrorist attacks in the United States last month have not slowed down the process of China′saccession to WTO.It is expected that China will eventually join WTO this November.Currently China isworking intensively...The terrorist attacks in the United States last month have not slowed down the process of China′saccession to WTO.It is expected that China will eventually join WTO this November.Currently China isworking intensively to revise its economic and foreign trade laws and regulations in conformity with the WTOrules.According to sources from the Ministry of Foreign Trade and Economic Cooperation(MOFTEC),China is to adopt the following measures to further encourage foreign investment in China.展开更多
Reform and opening up to the outside world constitutes a basic long-term state policy that China adheres to 20 odd years’ reform and development has brought about profound changes to the Chinese economy. First, China...Reform and opening up to the outside world constitutes a basic long-term state policy that China adheres to 20 odd years’ reform and development has brought about profound changes to the Chinese economy. First, China has transformed from a planned economy to展开更多
Accessibility is a factor affecting national park visitation.However,the effect of accessibility on national park visitation is not fully understood.This paper examines the relationship between U.S.national park visit...Accessibility is a factor affecting national park visitation.However,the effect of accessibility on national park visitation is not fully understood.This paper examines the relationship between U.S.national park visitation and accessibility.First,the global and local accessibility indexes of each park unit are computed based on an accessibility model that takes into account the surrounding population and its proximity to the park unit.Integrated in the model is a distance decay coefficient that is derived from U.S.national park visitor surveys and therefore pertinent to the case of study.Then correlation analysis is performed between park visitation and accessibility based on park types,regions,and visitation types.Results show that total visitation is positively related to accessibility in National Memorials,Military Parks and Battlefield Parks/Sites but negatively related to accessibility in national parks and national monuments.However,recreational overnight stay visits are commonly negatively correlated to accessibility for almost all park types.Moreover,local accessibility index displays enhanced correlation coefficients with improved significance levels in many categories of analysis.Results suggest that historical/cultural national parks which often show positive correlations tend to attract more local visitors,but nature-based parks which mainly show negative correlations tend to attract more distant visitors.展开更多
BACKGROUND Emergency situations in inflammatory bowel diseases(IBD)put significant burden on both the patient and the healthcare system.AIM To prospectively measure Quality-of-Care indicators and resource utilization ...BACKGROUND Emergency situations in inflammatory bowel diseases(IBD)put significant burden on both the patient and the healthcare system.AIM To prospectively measure Quality-of-Care indicators and resource utilization after the implementation of the new rapid access clinic service(RAC)at a tertiary IBD center.METHODS Patient access,resource utilization and outcome parameters were collected from consecutive patients contacting the RAC between July 2017 and March 2019 in this observational study.For comparing resource utilization and healthcare costs,emergency department(ED)visits of IBD patients with no access to RAC services were evaluated between January 2018 and January 2019.Time to appointment,diagnostic methods,change in medical therapy,unplanned ED visits,hospitalizations and surgical admissions were calculated and compared.RESULTS 488 patients(Crohn’s disease:68.4%/ulcerative colitis:31.6%)contacted the RAC with a valid medical reason.Median time to visit with an IBD specialist following the index contact was 2 d.Patients had objective clinical and laboratory assessment(C-reactive protein and fecal calprotectin in 91%and 73%).Fast-track colonoscopy/sigmoidoscopy was performed in 24.6%of the patients,while computed tomography/magnetic resonance imaging in only 8.1%.Medical therapy was changed in 54.4%.ED visits within 30 d following the RAC visit occurred in 8.8%(unplanned ED visit rate:5.9%).Diagnostic procedures and resource utilization at the ED(n=135 patients)were substantially different compared to RAC users:Abdominal computed tomography was more frequent(65.7%,P<0.001),coupled with multiple specialist consults,more frequent hospital admission(P<0.001),higher steroid initiation(P<0.001).Average medical cost estimates of diagnostic procedures and services per patient was$403 CAD vs$1885 CAD comparing all RAC and ED visits.CONCLUSION Implementation of a RAC improved patient care by facilitating easier access to IBD specific medical care,optimized resource utilization and helped avoiding ED visits and subsequent hospitalizations.展开更多
Alzheimer＇s disease（AD）：AD,a neurodegenerative disorder and a significant cause of dementia throughout the world mostly affects the older adults but sometimes also seen in young age（early state AD）（Agrawal et a...Alzheimer＇s disease（AD）：AD,a neurodegenerative disorder and a significant cause of dementia throughout the world mostly affects the older adults but sometimes also seen in young age（early state AD）（Agrawal et al.,2017）.展开更多
基金financially supported by the National Natural Science Foundation of China(32161143033 and 32001574)the Agricultural Science and Technology Innovation Program of CAAS(2060203-2).
文摘Understanding the composition and contents of carotenoids in various soybean seed accessions is important for their nutritional assessment.This study investigated the variability in the concentrations of carotenoids and chlorophylls and revealed their associations with other nutritional quality traits in a genetically diverse set of Chinese soybean accessions comprised of cultivars and landraces.Genotype,planting year,accession type,seed cotyledon color,and ecoregion of origin significantly influenced the accumulation of carotenoids and chlorophylls.The mean total carotenoid content was in the range of 8.15–14.72μg g–1 across the ecoregions.The total carotenoid content was 1.2-fold higher in the landraces than in the cultivars.Soybeans with green cotyledons had higher contents of carotenoids and chlorophylls than those with yellow cotyledons.Remarkably,lutein was the most abundant carotenoid in all the germplasms,ranging from 1.35–37.44μg g–1.Carotenoids and chlorophylls showed significant correlations with other quality traits,which will help to set breeding strategies for enhancing soybean carotenoids without affecting the other components.Collectively,our results demonstrate that carotenoids are adequately accumulated in soybean seeds,however,they are strongly influenced by genetic factors,accession type,and germplasm origin.We identified novel germplasms with the highest total carotenoid contents across the various ecoregions of China that could serve as the genetic materials for soybean carotenoid breeding programs,and thereby as the raw materials for food sectors,pharmaceuticals,and the cosmetic industry.
文摘Objective To introduce the accession procedure and evaluation of PIC/S,and help relevant departments in China to understand the requirements of PIC/S in detail,and to promote the process of China’s entry into PIC/S.Methods The procedures and steps of joining PIC/S,the evaluation process of PIC/S,and the experience of several countries in joining PIC/S were introduced and analyzed,which could help the relevant personnel in China understand the specific contents.Results and Conclusion According to the requirements of PIC/S,it is necessary to establish a unified GMP quality management system.
文摘The Ministerial Conference Decision of 10 NOV.2001 Having regard to paragraph 2 of Article Ⅻ and paragraph 1 of Article Ⅸ of the Marrakesh Agreement Establishing the World Trade Organization, and the Decision—Making Procedures under Articles Ⅸ and Ⅻ of the Marrakesh Agreement Establishing the World Trade Organization agreed by the General Council (WT/L/93). Taking note of the application 0f the People's Republic of China for accession to the Marrakesh Agreement Establishing the World Trade Organiza-
文摘The terrorist attacks in the United States last month have not slowed down the process of China′saccession to WTO.It is expected that China will eventually join WTO this November.Currently China isworking intensively to revise its economic and foreign trade laws and regulations in conformity with the WTOrules.According to sources from the Ministry of Foreign Trade and Economic Cooperation(MOFTEC),China is to adopt the following measures to further encourage foreign investment in China.
文摘Reform and opening up to the outside world constitutes a basic long-term state policy that China adheres to 20 odd years’ reform and development has brought about profound changes to the Chinese economy. First, China has transformed from a planned economy to
基金supported by the National Nature Science Foundation of China (Grant No. 41401604)the Central Universities Fund Project of Southwest Minzu University (Grant No. 2019SYB07)
文摘Accessibility is a factor affecting national park visitation.However,the effect of accessibility on national park visitation is not fully understood.This paper examines the relationship between U.S.national park visitation and accessibility.First,the global and local accessibility indexes of each park unit are computed based on an accessibility model that takes into account the surrounding population and its proximity to the park unit.Integrated in the model is a distance decay coefficient that is derived from U.S.national park visitor surveys and therefore pertinent to the case of study.Then correlation analysis is performed between park visitation and accessibility based on park types,regions,and visitation types.Results show that total visitation is positively related to accessibility in National Memorials,Military Parks and Battlefield Parks/Sites but negatively related to accessibility in national parks and national monuments.However,recreational overnight stay visits are commonly negatively correlated to accessibility for almost all park types.Moreover,local accessibility index displays enhanced correlation coefficients with improved significance levels in many categories of analysis.Results suggest that historical/cultural national parks which often show positive correlations tend to attract more local visitors,but nature-based parks which mainly show negative correlations tend to attract more distant visitors.
文摘BACKGROUND Emergency situations in inflammatory bowel diseases(IBD)put significant burden on both the patient and the healthcare system.AIM To prospectively measure Quality-of-Care indicators and resource utilization after the implementation of the new rapid access clinic service(RAC)at a tertiary IBD center.METHODS Patient access,resource utilization and outcome parameters were collected from consecutive patients contacting the RAC between July 2017 and March 2019 in this observational study.For comparing resource utilization and healthcare costs,emergency department(ED)visits of IBD patients with no access to RAC services were evaluated between January 2018 and January 2019.Time to appointment,diagnostic methods,change in medical therapy,unplanned ED visits,hospitalizations and surgical admissions were calculated and compared.RESULTS 488 patients(Crohn’s disease:68.4%/ulcerative colitis:31.6%)contacted the RAC with a valid medical reason.Median time to visit with an IBD specialist following the index contact was 2 d.Patients had objective clinical and laboratory assessment(C-reactive protein and fecal calprotectin in 91%and 73%).Fast-track colonoscopy/sigmoidoscopy was performed in 24.6%of the patients,while computed tomography/magnetic resonance imaging in only 8.1%.Medical therapy was changed in 54.4%.ED visits within 30 d following the RAC visit occurred in 8.8%(unplanned ED visit rate:5.9%).Diagnostic procedures and resource utilization at the ED(n=135 patients)were substantially different compared to RAC users:Abdominal computed tomography was more frequent(65.7%,P<0.001),coupled with multiple specialist consults,more frequent hospital admission(P<0.001),higher steroid initiation(P<0.001).Average medical cost estimates of diagnostic procedures and services per patient was$403 CAD vs$1885 CAD comparing all RAC and ED visits.CONCLUSION Implementation of a RAC improved patient care by facilitating easier access to IBD specific medical care,optimized resource utilization and helped avoiding ED visits and subsequent hospitalizations.
文摘Alzheimer＇s disease（AD）：AD,a neurodegenerative disorder and a significant cause of dementia throughout the world mostly affects the older adults but sometimes also seen in young age（early state AD）（Agrawal et al.,2017）.
