Geology and Geochemistry of K-feldspar Veins in Lamprophyre at the Zhenyuan Gold Deposit,Yunnan,Southwest China:Implications for Gold Mineralization

Lamprophyres typically appear in hydrothermal gold deposits.The relationship between lamprophyres and gold deposits is investigated widely.Some researchers suggest that the emplacement of lamprophyres triggers gold mineralization,whereas others hypothesize that the formation of lamprophyres increases the fertility of mantle sources and ore-forming fluids.K-feldspar veins,with ages between those of lamprophyres and gold deposits,appear in lamprophyres in Zhenyuan.Therefore,K-feldspar veins are ideal for investigating the relationship between lamprophyres and gold deposits.Phlogopite in K-feldspar veins has lower Mg#,Ni,and Cr contents and higher TiO2,Li,Ba,Sr,Sc,Zr,Nb,and Cs contents than phlogopite in lamprophyres.The in-situ Sr isotopic values of apatites(0.7063–0.7066)in K-feldspar veins are within the range for apatites(0.7064–0.7078)from lamprophyres.High large-ion lithophile element concentrations and low Nb and Ta concentrations in phlogopite from lamprophyres,in addition to high(87Sr/86Sr)i values of apatite(0.7064–0.7078),indicate that the magma parental to these phlogopite and apatite crystals is derived from an enriched mantle.Kfeldspar veins are genetically correlated with lamprophyres,whereas sulfide mineral assemblage and trace element compositions of pyrite in K-feldspar veins suggest that K-feldspar veins in lamprophyres are not directly related to gold mineralization of the Zhenyuan deposit.

Analysis on Tourist Satisfaction Degree and Its Measuring Indexes in Tourist Area——A Case Study of Zhenyuan Ancient City of Guizhou Province

By using principal component analysis,this paper had modified and put forward a theoretical model of evaluation on tourist satisfaction degree with tourist perception quality and tourist satisfaction degree as structure variables and with thirty indexes like image of tourist area,tourists' expectation,infrastructure in tourist area,landscape features and ticket price as observed variables,based on random questionnaire survey of tourists of Zhenyuan ancient city in Guizhou Province and the existing evaluation models of tourist satisfaction degree at home and abroad.The survey result showed that tourist satisfaction degree was not high,that tourists were dissatisfied with observing facilities,transportation,accommodation and landscape features,and that the attraction power of tourist area was weak.The comprehensive tourist satisfaction degree of Zhenyuan ancient city was 77.653.Therefore,the government should enhance reconstruction of infrastructure and construction of landscape features,and improve tourist service quality level,so as to realize sustainable development of tourist economy in Zhenyuan ancient city.

Alteration and mineralization styles of the orogenic disseminated Zhenyuan gold deposit, southeastern Tibet: Contrast with carlin gold deposit

Orogenic disseminated and Carlin gold deposits share much similarity in alteration and mineralization.The disseminated orogenic Zhenyuan Au deposit along the Ailaoshan shear zone,southeastern Tibet,was selected to clarify their difference.The alteration and mineralization from the different lithologies,including meta-quartz sandstone,carbonaceous slate,meta-(ultra)mafic rock,quartz porphyry and lamprophyre were researched.According to the mineral assemblage and replacement relationship in all types of host rocks,two reactions show general control on gold deposition:(1) replacement of earlier magnetite by pyrite and carbonaceous material;(2) alteration of biotite and phlogopite phenocrysts in quartz porphyry and lamprophyre into dolomite/ankerite and sericite.Despite the lamprophyre is volumetrically minor and much less fractured than other host rocks,it contains a large portion of Au reserve,indicating that the chemically active lithology has played a more important role in gold precipitation compared to structure.LA-ICP-MS analysis shows that Au mainly occurs as invisible gold in fine-grained pyrite disseminated in the host rocks,with Au content reaching to 258.95 ppm.The diagenetic core of pyrite in meta-quartz sandstone enriched in Co,Ni,Mo,Ag and Hg is wrapped by hydrothermal pyrite enriched in Cu,As,Sb,Au,Tl,Pb and Bi.Different host rock lithology has much impact on the alteration and mineralization features.Carbonate and sericite in altered lamprophyre show they have higher Mg than those developed in other of host rocks denoting that the carbonate and sericite incorporated Mg from phlogopite phenocrysts in the primary lamprophyre during alteration.The ore fluid activated the diagenetic pyrite in meta-quartz sandstone leading the hydrothermal pyrite enriched in Cu,Mo,Ag,Sb,Te,Hg,Tl,Pb and Bi,but the hydrothermal pyrite in meta-(ultra)mafic rock is enriched in Co and Ni as the meta-(ultra)mafic rock host rock contain high content of Co and Ni.However,Au and As shear similar range in both types of host rocks indicating that these two elements most likely come from the deep source fluid rather than the host rocks.It was shown in the disseminated orogenic gold deposit that similar hydrothermal alteration with mineral assemblage of carbonate (mainly dolomite and ankerite),sericite,pyrite and arsenopyrite develops in all types of host rocks.This is different from the Nevada Carlin type,in which alteration is mainly dissolution and silicification of carbonate host rock.On the other hand,Au mainly occur as invisible gold in both disseminated orogenic and Carlin gold deposits.

Geochronology and Geochemistry of the Granite Xenolith within the Lamprophyre at the Zhenyuan Gold Deposit(Yunnan Province, SW China)

The xenoliths in host rocks of hydrothermal gold deposits can generally provide much geochemical information of the deep rocks, which may have an implication for the sources of ore-forming materials. Geochronology and geochemical characteristics are reported for a granite xenolith, which is enclosed by the lamprophyre in the Zhenyuan gold deposit(Yunnan Province, SW China). This granite xenolith mainly consists of K-feldspar, quartz, and plagioclase with trace amounts of magnetite, titanite, apatite, zircon, and sulfides. Zircons from the granite xenolith yield a weighted average U-Pb age of 281.1 ± 1.3 Ma(MSWD = 2.1), which could represent the crystallization age of this granite xenolith. The Ti-in-zircon geothermometer and the Mn concentration in apatite calculate that this granite xenolith formed at 685 ± 43℃ with the logf_(O2) values ranging from NNO + 3.7 to NNO + 6.4. The zircons in the granite xenolith have a restricted range of positive ε_(Hf)(t) values ranging from +9.4 to +10.8, and the corresponding Hf TDM2 model ages range from 588 to 678 Ma. The zircon U-Pb age and the Hf isotopic compositions indicate this granite xenolith within the lamprophyre is mainly derived from partial melting of juvenile crustal rocks before the completed closure of the Ailaoshan Ocean. The pyrites in the granite xenolith have higher Bi concentrations, and lower As, Sb, and Tl concentrations than the gold-bearing pyrites of the ores in the Zhenyuan gold deposit. The low Au concentrations of the pyrites together with the ore-forming age of the Zhenyuan gold deposit(Oligocene) indicate the granite xenolith may have limited contribution to the gold mineralization of the Zhenyuan gold deposit.

Effect of Sacubitril-Valsartan Combined with Zhenyuan Capsule in the Treatment of Chronic Heart Failure Comorbid Anxiety and Depression and Its Effect on Inflammatory Factors

Objective: To investigate the effect of sacubitril-valsartan combined with Zhenyuan capsule in the treatment of chronic heart failure comorbid anxiety and depression and its effect on the level of inflammatory factors. Methods: A total of 106 patients with chronic heart failure comorbid anxiety and depression from February 2020 to March 2022 were continuously enrolled and divided into control group (36 cases), observation group A (36 cases) and observation group B (34 cases) according to treatment methods. All groups were given conventional treatment. On the basis of routine treatment, the control group, observation group A and observation group B were given valsartan, sacubitril-valsartan and sacubitril-valsartan plus Zhenyuan Capsules for the treatment of consecutive 8 weeks. The patients in the 3 groups were evaluated by the Self-rating Anxiety Scale (SAS) and Self-rating Depression Scale (SDS) before and after treatment, and the clinical efficacy of heart failure was evaluated, and the detection of left ventricular ejection fraction (LVEF), left ventricular end systolic diameter (LVESD), left ventricular end-diastolic diameter (LVEDD), N terminal brain natriuretic peptide (NT-proBNP), tumor necrosis factor alpha (TNF alpha), interleukin 6 (IL-6), c-reactive protein (CRP) was conducted. Results: The clinical efficacy rate and total effective rate of heart failure in observation group A and observation group B were significantly higher than those in the control group (P < 0.05), and the observation group B was higher than the observation group A (P < 0.05);SAS and SDS scores in observation group A and observation group B were significantly lower than the control group (P < 0.05), and observation group B was lower than observation group A (P < 0.05);The LVEF in the three groups was all increased compared with those before treatment, and the levels of LVESD, LVEDD, NT-proBNP, TNF-α, IL-6, and hs-CRP were all decreased compared with those before treatment;The changes of above indexes in observation group A and observation group B were more significant than those in control group (P < 0.05). Except for the LVEDD index, the observation group B had significant changes compared with the observation group A (P < 0.05). Conclusion: Sacubitril valsartan can improve cardiac function, reduce inflammatory response, and improve anxiety and depression in patients with chronic heart failure, and the treatment effect of combination with Zhenyuan Capsule is more significant.

Contents of Fixed-Ammonium (NH_4^+) in Lamprophyres in the Zhenyuan Gold Orefield, Yunnan Province, China: Implications for Its Characteristics of the Source Region

This paper determined the fixed-ammonium (NH+-4) contents of lamprophyres in the Zhenyuan gold orefield, Yunnan Province, China. The results show that the NH+-4 contents of minettes in the orefield range from 120×10-6 to 469×10-6 and those of kersantites from 74.3×10-6 to 136×10-6. These values are higher than those of other mantle-derived rocks (less than 50×10-6), but lower than those of carbonaceous wall rocks in the orefield (from 1200×10-6 to 1343×10-6). Combining with the Sr isotopic composition, this paper suggested that lamprophyres in the orefield with high NH+-4 contents relative to other mantle-derived rocks would not have resulted from the primary magma contaminated by crustal materials in the process of rising or in the magma chamber, but from mantle metasomatism.

西南山区乡村贫困地域系统时空演化格局研究——以云南省镇沅县为例

在梳理总结国内外关于贫困地理与农村多维空间贫困、乡村地域系统与贫困地域系统理论前沿研究的基础上,提出“乡村贫困地域系统”研究视角,并对乡村贫困地域系统理论内涵进行了初步探析.以云南省镇沅县109个村域为评价分析单元,构建了乡村贫困地域系统演化发展评价指标体系,设计了乡村贫困地域系统演化发展指数测度模型和基于“时空立方体—新兴时空热点分析”的时空演化模式识别方法.研究显示:(1)镇沅县2013-2021年乡村贫困地域系统演化时序阶段性特征经历了“差异波动演化(2013-2015年)—快速演化(2016-2019年)—增长滞缓趋稳(2020-2021年)”3个主要阶段.(2)镇沅县乡村贫困地域系统时空演化模式以连续热点模式为主,加强的热点模式呈零星分布,表征2013-2021年镇沅县乡村贫困地域系统整体上经历了较快且连续稳定的减贫演化过程,是减贫政策普惠作用在时空演化模式上的具体表现;连续冷点模式和持续冷点模式呈现出县域东西两端集聚分布态势.(3)多维空间贫困陷阱主要集中在和平镇、者东镇、振太镇的部分村域,相关村域脱贫稳定性相对较差、返贫风险较高.乡村发展是乡村地域系统循环累积与动态演化的结果,深入刻画分析乡村贫困地域系统时空演化格局与特征,对于科学推动脱贫地区转型发展具有重要意义.

基于Zhenyuan积分的直觉模糊多属性决策方法

针对属性之间具有相互关联关系的直觉模糊多属性决策问题,提出一种基于Zhenyuan积分的决策方法.首先提出直觉模糊Zhenyuan积分平均(IFZA)算子;然后探讨IFZA算子的优良性质以及与现有直觉模糊集成算子的关系,研究表明,IFZA算子可以改进现有直觉模糊奇异积分算子的缺陷,能够全面度量属性之间的相互关联关系;最后提出一种基于IFZA算子的属性间具有相互关联关系的直觉模糊多属性决策方法,并通过实例验证所提出方法的有效性和可行性.

鄂尔多斯盆地西南缘浅埋藏储层致密化成因

鄂尔多斯盆地西南缘镇原地区三叠系延长组8段细粒砂岩在较浅的埋藏条件下便发生了致密化。综合利用岩心分析、铸体薄片、扫描电镜与图像分析等技术,对其孔喉及成岩特征进行分析。结果表明:储层的成分及结构成熟度较低,孔隙结构以细孔—微细喉型为主,压实作用强烈,并且具有多期胶结与多期溶解的特征。以储层的“埋藏史-油气充注史-成岩演化序列-孔隙结构”为约束条件对储层的致密化定量表征发现,长8段在稳定的构造背景与辫状河三角洲环境的控制下,形成了细粒、富含塑性颗粒且高杂基含量的沉积,配合其后的快速埋深造成了强烈压实,其对储层致密化的贡献值为85%。成岩环境的多期变化造成了富集不同盐类的孔隙流体对储层的强烈胶结作用,对储层致密化贡献值为40.8%。早期绿泥石膜对颗粒的保护、稳定的构造背景及顶底板围岩处的硅质与钙质胶结层对孔隙流体活动的限制、过早的低渗和远离盆地生烃中心造成的缺乏酸性流体持续性注入等导致了溶蚀作用较弱,对储层致密化的抑制值仅为26.1%,且形成的次生孔喉易被后期胶结物充填。构造、沉积、成岩作用及其与油气充注在时空的耦合关系造成了长8段储层在浅埋藏条件下的致密化。

乡村振兴背景下民族特色小镇旅游发展研究--以贵州省镇远古镇为例

特色小镇是集文化、产业等多功能为一体的经济发展平台,高度契合乡村振兴发展战略。镇远古镇具备资源类型多样、设施相对完善、项目初见成效、多元主体协同发展等比较优势,但同时存在科旅融合成效不佳、营销渠道亟待优化、旅游项目感知度低、服务水平有待提升等问题。基于此,从加快科旅融合步伐、不断完善营销渠道、提高旅游感知度、提升旅游服务水平等方面提出相应的措施,在加快镇远旅游业赋能乡村振兴的同时也为其他区域发展提供参考借鉴。

陈永灿从“本虚毒结”论治慢性萎缩性胃炎伴肠上皮化生经验浅析

[目的]总结陈永灿主任基于“本虚毒结”治疗慢性萎缩性胃炎伴肠上皮化生的经验。[方法]通过随师临诊,收集、整理典型医案,结合陈主任临证的阐释,从核心病机、辨证论治、遣方用药三个方面,总结陈主任临床治疗慢性萎缩性胃炎伴肠上皮化生的经验,并附一则验案予以佐证。[结果]慢性萎缩性胃炎伴肠上皮化生是胃癌发生发展的关键环节,陈主任认为“本虚毒结”是慢性萎缩性胃炎伴肠上皮化生的核心病机,“本虚”即脾胃虚弱,元气不足;“毒结”即浊毒留滞,蕴结隐伏。辨治以寒热错杂为基本面,主张平调寒热,根据虚实偏胜,随证治之。处方以自拟十味泻心汤为主,扶元解毒,如脾虚及肾,加用滋肾之品;兼有气血怫郁,喜用花类疏和;针对痰毒、瘀毒、热毒的不同,分别选用山慈菇、石见穿、猫人参,蜂房、刘寄奴、莪术,蒲公英、半枝莲、白花蛇舌草三对角药治之。验案辨证为脾虚毒结、寒热错杂,治法为健脾解毒、平调寒热,以十味泻心汤为主方,考虑兼有瘀毒阻滞、浊滞血瘀,选用蜂房-刘寄奴-莪术角药;复诊因气血不通,气机升降失调,以三花百草饮轻宣开郁;三诊考虑患者年龄增长,肝肾渐衰,且久病伤元,合四君贞元饮健脾益肾、固本培元。[结论]陈主任从“本虚毒结”辨治慢性萎缩性胃炎伴肠上皮化生经验独到,疗效显著,值得推广学习。

补肾健脾中药复方激活AMPK信号通路抑制雌激素缺乏小鼠超重

【目的】观察补肾健脾中药复方(振元颗粒)对雌激素缺乏所致小鼠超重的干预效果及机制。【方法】构建卵巢摘除雌性小鼠模型,观察连续14周灌胃振元颗粒对小鼠体质量和脂肪堆积的影响。构建小鼠3T3-L1前脂肪细胞模型,观察振元颗粒干预对成脂分化的影响。检测小鼠脂肪组织和3T3-L1细胞中调控脂肪细胞形成和脂肪合成的关键基因/蛋白的表达情况,探讨振元颗粒体内外减脂作用的机制。【结果】振元颗粒干预显著降低卵巢摘除小鼠的体质量增量(P<0.01)、性腺周围和腹股沟脂肪指数(P<0.05),显著抑制前脂肪细胞向脂肪细胞的分化,显著下调脂肪组织和3T3-L1细胞中过氧化物酶体增殖物激活受体γ(PPARγ)、胆固醇调节元件结合蛋白1c(SREBP-1c)、乙酰辅酶A羧化酶1(ACC1)和脂肪酸合酶(FAS)表达水平(P<0.05),显著提高腺苷酸活化蛋白激酶(AMPK)和ACC1的磷酸化水平(P<0.05)。【结论】振元颗粒能抑制脂肪细胞生成,改善雌激素缺乏造成的雌性小鼠超重,其机制与激活AMPK信号通路有关。提示补肾健脾中药复方振元颗粒有助于绝经后女性的体质量控制。

On emplacement ages of lam-proites in Zhenyuan County,Guizhou Province,China

Emplacement ages of lamproites that comprise lamproite and olivine lamproite in Zhenyuan County, Guizhou Province, China, have been constrained by the whole-rock Sm-Nd and Rb-Sr isochron methods and the whole rock K-Ar method. Intrusive activities of lamproites in the Sinantang area of Zhenyuan County, Guizhou Province, took place during the Late Cambrian, as indicated by the Sm-Nd isochron ages (t) = (503±17) (2σ) Ma and by the Rb-Sr isochron ages (t) = (501.2±4.6) (2σ) Ma. Intrusive activities of olivine lamproites at the Maping with Ⅱ -type diamond and Xitou in Zhenyuan County, Guizhou Province, took place from the Late Cambrian to the Early Ordovician, as evidenced by the Sm-Nd isochron ages (t) = (502±27) (2σ) Ma and by the Rb-Sr isochron age (t) = (502± 27) (2σ) Ma. This suggests that the upwelling hot materials derived from the deep mantle were emplaced from the Late Cambrian to the Early Ordovician (503-497 Ma), while the time terminal of cooling of the geothermal event of

Characteristics of Ore-Forming Fluid in the Zhenyuan Gold Orefield, Yunnan Province, China

The Zhenyuan gold orefield is located in the Ailaoshan gold belt, Sanjiang metallogenic region, China. The fluid inclusions （FIs） in mineralized quartz samples, collected from four deposits, i.e., Laowangzhai , Donggualin , Kudumu , and Daqiaoqing, in the orefield, were studied to reveal ore-forming process. Only aqueous-type and H20-NaCl-type FIs were observed in the samples. Two generations of FIs are identified due to the spatial occurrences of FIs in host minerals. The early generation is located in the internal zone of quartz crystal, and it has higher homogenization temperatures varying from 180 to 255 ℃ and salinities ranging from 8.7% to 11%; the late generation, often with beating bubbles under room temperature, is developed in the quartz margin, its homogenization temperatures is lower within 95 to 160 ℃. After elimination of the late generation of FIs, early generation FIs compositions were tested. Gaseous phases in the FIs were H20 and CO2, with low contents of N2, CH4, and C2H6, and the liquids mainly contains Na＋, K＋, Ca^＋,Mg^2＋, CI, and SO_4^2-. The reappraisal of the previously published hydrogen and oxygen isotope results suggested that the early generation of ore-forming fluid was mainly primary magma hydrothermal, while the late generation fluid contains large amounts of meteoric water. Thus, the result showed that Zhenyuan gold orefield may differ from typical orogenic deposits, which contains abundant CO2-dominated FIs. The two generations FIs developed as quartz grew displaying a continuous evolution of the ore-forming fluids.

Mobility of elements during lamprophyre alteration and altered fluid characteristics in the Zhenyuan gold deposit

LAMPROPHYRES are one of the rock types which are easily subject to alteration. Alteration can not onlychange their texture and mineral assemblage, but also influence their geochemistry properties. The mostavailable data show that alteration will directly influence the content of Au in lamprophyre. For example,in the Superior area of Canada and the Yilgan area of Australia relatively fresh lamprophyres are bothlow in Au contents (3.9×10-9 and 1.7×10-9, respectively), but the contents of Au in altered lamprophyres from both areas are double increased (38×10-9 and 20×10-9 on average). Lamprophyres arewidely exposed in the Zhenyuan gold deposit, Yunnan Province and they are closely associated with goldmineralization both in space and in time. So the lamprophyres in the Zhenyuan gold deposit can be citedas the most typical example both at home and abroad. Lamprophyres in the mining district have undergonevarying-degree alteration and partly experienced mineralization. On the basis of the mass equilibrium e-

云南哀牢山金矿带镇沅超大型造山型金矿床碳质物特征及其成矿意义

哀牢山金矿带位于三江特提斯造山带的东南部,发育有一系列大型-超大型造山型金矿床,并广泛发育碳质物,但碳质物在金矿成矿过程中的作用还尚不明确。为了确定碳质物在金矿化过程中所扮演的角色,本研究以哀牢山金矿带镇沅超大型造山型金矿发现的不同种类的碳质物和共生黄铁矿为研究对象,对其进行了岩相学、拉曼光谱、傅里叶红外光谱、碳同位素和激光剥蚀电感耦合等离子体质谱(LA-ICP-MS)分析,研究结果表明镇沅金矿中有3类碳质物:CM1、CM2和CM3。CM1呈深灰色不规则形态,拉曼光谱分析显示CM1具有低强度、宽的D1带和高强度、窄的G峰,D2峰较明显,计算显示其形成温度为172~200℃,低于成矿温度(250~330℃)。此外,傅里叶红外分析结果表明CM1石墨化程度低,含较少的CH键和C=O键,表明其未经历热液蚀变。碳同位素分析显示CM1样品的δ^(13)C值为-26.46‰~-26.89‰。与CM1空间上共生的黄铁矿(Py1)呈草莓状分布于碳质板岩中,LA-ICP-MS结果表明Py1的Co、Ni、Zn、Mo、Te元素含量高;CM2呈灰色细长沥青状,拉曼光谱分析显示CM2的D1峰和G峰较CM1更为尖锐,面积近似,且D2峰的光谱分峰程度很低,计算显示其形成温度为358~463℃,高于成矿温度。傅里叶红外分析结果显示,CM2石墨化程度高,在2925 cm^(-1)和1705 cm^(-1)处有明显的谱峰,含有较多的CH_(2)+CH_(3)、C=O和C=C键。CM3呈灰色细小颗粒状,拉曼光谱分析显示CM3的光谱特征与CM1的相似,但CM3的D2峰具有独立的峰段,计算显示其形成温度为258~322℃,与成矿温度一致。碳同位素分析显示CM3的δ^(13)C值为-9.09‰~-14.12‰。与CM3空间上共生的黄铁矿(Py2)呈自形分布于含金石英脉中,LA-ICP-MS结果表明Py2的As、Au元素含量高。综合以上结果,笔者认为CM1来源于有机质,形成于碳质板岩的早期成岩阶段,属于变质成因,与其共生的Py1形成于成岩期,属于沉积成因的黄铁矿。CM2的形成温度高于成矿温度,也为变质成因。CM3源于成矿流体,形成于围岩中的含铁矿物和成矿流体发生反应,属于热液成因,而Py2与CM3从流体中同时沉淀。其中CM1和CM3在金矿化过程中起到重要的作用。CM1作为还原剂能够有效和成矿流体中金的硫氢络合物发生水岩反应促使金的沉淀,而CM3在硫化过程中和Py2共同沉淀导致成矿流体中H_(2)S的大量消耗,进一步破坏了金的硫氢络合物稳定性,导致金沉淀和再富集。

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白酒酿造与气候环境密切相关,优越的气候环境条件是生产优质白酒的重要因素之一。本文基于贵州镇远和仁怀1961—2022年7类气象数据,比较分析两地的气候环境条件。结果表明,镇远和仁怀气候温暖,年平均气温16℃左右,传统制曲时段(6—9月)平均最高气温30℃左右,超过30℃日数占比高;空气湿润,年平均降水量1000 mm左右,相对湿度终年维持在80%;日照较充足,年平均日照时数约为1200 h;风速低,平均风速为1~1.5 m/s。气候温暖、湿润、日照充足、风速小是两地共同的气候特征,给白酒酿制创造了独特的外部气候环境。

振源胶囊结合胺碘酮治疗慢性心力衰竭合并心律失常的临床效果观察

目的探究振源胶囊联合胺碘酮用于慢性心力衰竭伴心律失常的临床治疗效果。方法纳入2021年1月至2023年12月在本院收治的86例慢性心力衰竭合并心律失常患者(室性心律失常),随机分为对照组和研究组,每组各43例。对照组接受常规胺碘酮治疗,观察组接受振源胶囊结合胺碘酮治疗,均治疗3个月,观察两组患者临床疗效(心电图、心功能)、心律失常复发率及用药安全性。结果治疗3个月,研究组心电图恢复正常率86.05%、心功能改善总有效率95.35%,均高于对照组60.47%、76.74%(均P<0.05)。随访3个月,研究组心律失常复发率6.98%,低于对照组的27.91%(P<0.05)。研究组不良反应发生率4.66%,与对照组6.99%不存在统计学差异(P>0.05)。结论振源胶囊结合胺碘酮治疗慢性心力衰竭合并心律失常效果相比胺碘酮单药治疗,能够提升临床疗效,更好改善心功能,降低复发风险,且不增加不良反应。

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