融合专利SAO特征的早期专利价值评估方法

[研究目的]在知识产权强国战略背景下,存在着专利数量与质量不匹配、技术转化率较低的困境,评估早期专利价值对高价值专利培育工程和专利技术转化具有重要意义。[研究方法]提出一种融合专利SAO网络特征和文本特征的早期专利价值评估方法。首先,从专利摘要和标题中抽取主体-行为-客体(SAO)结构。其次,用社会网络分析法挖掘专利SAO网络的核心组件,得到专利SAO网络中心性特征。然后,将SAO结构序列文本输入Doc2Vec模型,得到专利SAO文本特征。最后,融合专利基础特征和SAO特征,构建基于AutoGluon自动机器学习框架的早期专利价值评估模型。[研究结论]以人工智能产业专利为例进行实证研究,实验结果表明引入专利SAO特征后,模型的准确率、召回率和F1值相比基准模型均提高了2%~5%,证明了专利SAO特征在识别早期高价值专利中的有效性。

适用于超高清视频的SAO硬件优化设计

样点自适应补偿(Sample Adaptive Offset,SAO)是高效视频编码(High Efficiency Video Coding,HEVC)的重要组成部分,能有效去除编码图像中的振铃效应,改善编码图像的主观质量。针对当前SAO滤波器处理速度慢和吞吐量较低的问题,基于6×6大小的基本信息统计单元采用亮色度并行处理的四级流水线设计,提出一种基于FPGA的适用于超高清视频(Ultra HD Video,UHD)的SAO硬件滤波器。实验结果表明,在Xilinx Virtex7 FPGA开发平台上,该架构仅占用了10.5k的查找表和6.2k的寄存器资源,工作主频最高可达250 MHz,支持8K@110 fps的超高清视频流处理。在相同分辨率条件下,相较于现有其它方案在逻辑资源及帧率方面更具优势。

基于SAO结构的颠覆性技术关联机会发现路径研究

[研究目的]对颠覆性技术的发展和关联进行识别及预测,有助于及时开展技术布局,在产业竞争中形成战略优势。[研究方法]以技术专利摘要为数据对象,提出了融合SAO结构抽取、LDA主题分析和链路预测的技术关联机会发现路径,并以脑机接口为例对方法进行了验证。[研究结论]脑机接口在自身技术迭代、医疗健康领域、扩展应用领域及多模态集成控制系统领域具有广阔的关联机会,与论文、专利、课题、新闻报道等多源技术报告的对比评估说明了该路径的可行性和有效性。

Research Progress of Zhuang Medicine Combined with Nanogels in Mastitis

Mastitis is a common and frequently-occurring disease among Chinese women, which seriously harms their mental and physical health. External application of Zhuang medicine has the effects of dredging collaterals, relieving pain, promoting blood circulation, removing blood stasis, and softening hardness to dissipate stagnation, and show definite curative effect in preventing and treating breast diseases. Nano-composite hydrogels have the advantages of small toxic and side effects, high bioavailability, high targeting and controllable drug release. Therefore, this paper summarized and analyzed relevant literature of Zhuang medicine in treating breast diseases and clinical research of nanogels, providing new ideas and scientific basis for the treatment of mastitis with Zhuang medicine combined with nanogels.

Sequential experimental observation on the curative effect of Yingbupu decoction of Zhuang medicine on stage I and II acute kidney injury

Objective:To observe the clinical efficacy of the Zhuang medicine Yingbupu decoction on stage I and II acute kidney injury through sequential test.Methods:The open one-way qualitative response sequential design of experiments was adopted,and the patients with AKI in phase I and II who met the inclusion criteria were divided into the treatment group and the control group according to the order of hospitalization by random number table.On the basis of basic treatment,the treatment group was treated with Zhuang medicine Yingbupu decoction,and the control group was treated with Jinshuibao tablet.The clinical efficacy,TCM syndrome score,24 h urine volume,serum creatinine(Scr),microalbumin in urine(mAlb),neutrophil Gelatinase related lipid delivery albumin(NGAL)of the two groups were compared,and the adverse reactions and complications of the two groups were observed.Results:After 14 d of treatment,when the treatment group reached the 10th case,the experimental line contacted the upper bound U-line and reached the experimental standard to terminate the experiment.The effective hypothesis was accepted,and it was believed that the Zhuang medicine Yingbupu decoction had a therapeutic effect on stage I and II AKI.The conclusion was drawn that the treatment group received the Zhuang medicine Yingbupu.The clinical effective rate and improvement days were similar between the two groups,and there was no significant difference(P>0.05).However,the integral value of traditional Chinese medicine syndrome in the treatment group was lower than that in the control group(P<0.05),After treatment,the Scr,mAlb,and NGAL levels of patients in both groups were lower than before treatment(P<0.05).After treatment,the Scr,mAlb,and NGAL values in the treatment group were significantly lower than those in the control group(P<0.05).After treatment,the 24-hour urine volume in both groups was higher than that before treatment,and the values in the treatment group were significantly higher than those in the control group(P<0.05).During the treatment period,there were no significant adverse reactions or complications in either group.Conclusion:The Zhuang medicine Yingbupu decoction is effective in treating stage I and II AKI,and the Zhuang medicine Yingbupu can significantly improve the symptoms and quality of life of patients with stage I and II AKI.Its improvement of renal function is better than that of Jinshuibao tablets,and its safety is good.

A Study on the Translation of Plant Images in Qu Yuan’s Li Sao

The renowned masterpiece“Li Sao”by Qu Yuan contains numerous plant images for“expressing emotions and aspirations.”Exploring methods of translating plant imagery has greatly assisted in disseminating Chinese classical culture and facilitating cross-cultural communication.This study conducts a comparative analysis of three translations of“Li Sao”by Xu Yuanchong,Yang Xianyi,and Hawkes,aiming to understand the different approaches to translating plant imagery and explore variations in translation effectiveness.Through data collection,comparative analysis,and case studies,this research reveals that Xu Yuanchong emphasizes free translation,Yang Xianyi tends towards literal translation,and Hawkes adopts a combination of literal,free,and phonetic translation methods.

基于SAO-LightGBM算法的致密砂岩储层孔隙度预测方法

孔隙度是评价储层物性的关键参数,四川盆地中部NC地区钻井取心资料有限,储层孔隙度直接获取难度大,而基于常规测井资料的传统孔隙度预测方法误差大、精度低。为了明确NC地区致密砂岩气藏储层物性特征,以上三叠统须家河组四段储层为研究对象,提出了一种改进的机器学习算法SAO-LightGBM;使用该算法分析了孔隙度与地球物理测井参数之间的深层次潜在关系,指出了研究区储层孔隙度与声波时差、密度、中子孔隙度、地层电阻率和自然伽马具有较强的相关性,并基于以上测井参数建立了孔隙度预测模型。研究结果表明:①采用SAO优化算法独特的双重种群机制、高效的探索与利用策略,可以快速寻找到LightGBM的最优超参数组合,提升了模型的预测能力;②在测试数据集上,SAO-LightGBM的平均绝对误差为3.37%,决定系数为0.92。结论认为,较之于其他常规模型,SAO-LightGBM具有更为可靠的预测能力,能够高效完成目标层位孔隙度的预测工作,对NC地区的储层研究和后期勘探开发具有指导作用。

Research Overview of Zhuang Medicine Fumigation Lotions

At present,there is little research on the application of Zhuang medicine fumigation lotions in skin diseases,and there is no research on related preparation processes and quality standards.In this paper,the characteristics of its formulation and the research progress in skin diseases are reviewed,in order to deepen the understanding of Zhuang medicine fumigation lotions and provide a more detailed theoretical basis for its clinical research,development and application.

Observation on Therapeutic Effect of Lotus Needle Cupping Therapy for Removing Blood Stasis in Zhuang Medicine on PHN and Its Influ-ence on Inflammatory Mediators

[Objectives]To observe the clinical effect of the lotus needle cupping therapy for removing blood stasis in Zhuang medicine in treating PHNand its influence on inflammatory factors.[Methods]96 patients with PHN were randomly divided into three groups:lotus nee-dle cupping therapy group,TCM surrounding acupuncture group and gabapentin group.Venous blood and acupoint blood were collected at 0,21 and 42 d of treatment,and the expression levels of 5-HT,SP and CGRPinflammatory mediators were detected before and after treatment.The changes of VAS scores before,during and after treatment and the clinical efficacy were observed.[Results]The total effective rate of the lotus needle cupping group was 87.50%,which was better than that of the TCM acupuncture group(81.25%)and the gabapentin group(62.50%);after treatment,the VAS scores and the expression of inflammatory mediators in the three groups of patients were lower than those before treatment,and the decrease was more significant in the treatment group(P<0.05).[Conclusions]The lotus needle cupping therapy for removing blood stasis in Zhuang medicine is effective in treating PHN,and its mechanism is to reduce the release of inflammatory media-tors,reduce hyperalgesia,relieve pain and improve the quality of life of patients.

自组装脂质体纳米载体对骨肉瘤细胞Saos-2靶向递送及凋亡的影响

目的以天然脂肪酸月桂酸和硬脂酸为骨架,利用它们在二甲基甲酰胺(dimethylformamide,DMF)中的自组装构建了一种脂质体纳米载体并负载阿霉素,对其靶向人骨肉瘤细胞Saos-2及凋亡情况进行考察.方法采用自组装制备了负载阿霉素的脂质体纳米载体,采用激光共聚焦考察了其靶向人骨肉瘤细胞Saos-2能力,采用Annexin V-FITC染色技术考察了脂质体纳米载体对人骨肉瘤细胞Saos-2凋亡的影响.结果自组装脂质体纳米载体与人骨肉瘤细胞Saos-2孵育48h时,荧光强度最高,绿色荧光的自组装脂质体纳米载体会围绕在骨肉瘤细胞Saos-2周围,相对于同剂量DMF的对照组,自组装脂质体纳米载体组的细胞无论是早期凋亡还是晚期凋亡的比例均有所增加.结论负载阿霉素的脂质体纳米载体能准确地靶向人骨肉瘤细胞Saos-2,并加速人骨肉瘤细胞Saos-2的凋亡.

Study on the Promoting Role of Animating Zhuang Non-Heritage Folktales in the Ethnic Culture Industry

This study aims to explore the role of animating Zhuang non-heritage folktales in promoting the national culture industry.Using literature research,case studies,and comparative research methods,the positive impacts are analyzed in depth across four dimensions:cultural value inheritance,market demand,dissemination channels,and industrial innovation.The results show that animating Zhuang non-heritage folktales can help inherit national culture,meet market demand,broaden communication channels,and promote industrial innovation.Finally,this paper proposes corresponding policy suggestions and implementation paths to provide references for the sustainable development of the ethnic culture industry.

On the International Dissemination of Zhuang Medicine

As an important part of Chinese culture,Zhuang medicine has a long history and unique diagnosis and treatment.With the international dissemination of Chinese culture,the international dissemination of Zhuang medicine has become an increasing concern.This paper aims to discuss the status quo,challenges of the international dissemination of Zhuang medicine,then puts forwards corresponding solutions and recommendations,so as to make Zhuang medicine known by the world.

Analysis of the Innovation of Zhuang Medical Culture from the Perspective of a Comprehensive Well-Off Society: Insights from Social Research and Public Engagement

Based on the inheritance and development of Zhuang medicine culture from the perspective of a comprehensive well-off society,traditional Chinese medicine is a treasure of Chinese civilization.The inheritance,innovation,and development of traditional Chinese medicine are crucial to the cause of socialism with Chinese characteristics in the new era.By engaging young people,reducing the aging of the medical team,and understanding the views and suggestions of various groups on Zhuang medicine culture,questionnaire surveys,field interviews,literature searches,and other methods were employed to gather and analyze public opinions and suggestions on Zhuang medicine.Additionally,online consultations were conducted to assess the popularity of Zhuang medicine and identify existing problems.Based on these findings,recommendations and strategies for improvement were formulated.Furthermore,the design of an online consultation app is proposed to enhance the role and effectiveness of Zhuang medicine’s inheritance and development.

Innovation Transformation and Industry-Education Integration:A Study on the Integration Path of Guangxi Zhuang’s Intangible Cultural Heritage and Master of Arts Education in China

This study focuses on the master of arts education in higher education institutions in Guangxi Zhuang Autonomous Region of China,explores the path of integrating Guangxi Zhuang’s intangible cultural heritage with the teaching of master of arts,and puts forward the teaching mode of“thinking guidance-autonomous judgement-program construction.”A theoretical model of innovative transformation of intangible cultural heritage is also summarized.Through the development of this study,it is expected to further enrich the practical teaching mechanism of master of arts education in Chinese universities and form a master of arts teaching model with strong local cultural characteristics.At the same time,the teaching reform based on the integration of Guangxi Zhuang’s intangible cultural heritage and master of arts education also has strong practical significance for promoting the inheritance and innovation of Chinese intangible cultural heritage,promoting the development of cultural and creative industries,and serving the economic and social development of Guangxi.

基于SAO的技术主题创新演化路径识别及其可视化研究

利用专利文献数据识别技术领域的技术主题演化发展路径并分析其发展趋势,对于科技界、企业界进行专利技术创新具有重要的意义。首先,使用Open IE 5.1进行SAO(subject-action-object)三元组抽取,基于LDA(latent Dirichlet allocation)模型进行主题识别,根据TRIZ技术创新思想,基于action语义词典将技术主题划分到四个维度;然后,通过计算SAO三元组之间的相似度来测度技术主题之间的语义关联构建技术主题创新演化路径,并利用可视化技术构建技术主题创新演化路径可视化图谱,利用该图谱辅助分析技术主题演化脉络及其发展趋势。最后,通过石墨烯超级电容器(集流体)领域的实证,对该领域的技术问题(problem to problem,P-P)主题、技术功能(solution to solution,S-S)主题、解决方案(problem to solution,P-S)主题和技术效果(solution to problem,S-P)主题的创新演化路径进行解读分析,验证了本研究提出方法的可行性和有效性。

基于SAO结构的关键技术要素识别研究——以高速芯片为例

面对日益严峻的技术封锁及遏制风险,深入技术本身,掌握技术系统内部关键组件、工艺以及方法等技术要素是突破技术瓶颈的关键环节。归纳关键技术要素的3个特征--关键性、创新性以及基础性。以高速芯片为例,利用专利文献数据,分析高速芯片专业术语。引入SAO(Subject-Action-Object)语义结构,提取高速芯片技术要素,以技术要素为节点、技术要素关联强度为边,构建高速芯片SAO语义网络。借鉴社会网络分析方法,量化技术要素权利、地位以及创新力,识别高速芯片系统内关键技术要素,探究高速芯片技术结构,寻找技术卡点。实证结果显示,高速芯片“卡脖子”技术中存在“高速数据”“单片微机”“fpga芯片”“晶圆”4个关键技术要素。

基于SAO的专利数据驱动产品创新设计

借助大数据挖掘技术,提出基于主语-谓语-宾语(SAO)的专利数据驱动产品创新设计方法。首先通过语义依存句法挖掘专利文本数据库中的SAO结构,获取产品元件之间的作用关系信息;其次构建面向产品系统的复杂网络知识模型,并引入结构洞理论计算复杂网络中元件约束性系数,以此确定创新目标元件,并借助Word2Vec计算元件语义相似性系数,利用SAO相似性算法计算功能相似性系数;在此基础上,融合推荐算法以及组合矩阵,分别围绕结构创新、功能创新以及功能优化三个方面实现产品创新。最后以具有典型代表性的卫浴花洒产品为例,对所提方法进行了详细的演示,充分证实了所提方法的有效性和先进性。

Summary and clinical application of Zhuang medicine medicated thread moxibustion

Zhuang medicine medicated thread moxibustion is a kind of external therapy with ethnic medicine characteristics that spreads in Guangxi Zhuang region.It has a wide range of clinical application and significant curative effect,and can be used to treat diseases such as internal medicine,surgery,dermatology,gynecology,pediatrics,and five sense organs.Through reviewing and combing the literature on the Zhuang medicine medicated thread moxibustion in recent years,this paper summarizes and prospects its clinical application,with a view to further explaining the basic principles and application rules of Zhuang medicine medicated thread moxibustion and digging its clinical value.

Application Research of Artificial Intelligence in the Innovation of Zhuang Brocade Digital Art: Taking “The Speech of Zhuang Brocade” as an Example

Purpose: Based on the dilemma faced by the digitization of Zhuang Brocade intangible cultural heritage in Guangxi and the analysis of the advantages of artificial intelligence art in the digitization and innovation of intangible cultural heritage, this study explores the application path of the digital inheritance and dissemination of Zhuang Brocade in Guangxi by relying on the current theory and practice of artificial intelligence art, and provides reference significance for the inheritance and dissemination of intangible cultural heritage through artificial intelligence art. Method: Through in-depth analysis of the types, characteristics, and cultural connotations of Zhuang Brocade patterns in Guangxi, machine learning is performed using StyleGAN’s adversarial neural network, and digital art works are generated by applying Clip-style. The feasibility of developing digital resources for Zhuang Brocade intangible cultural heritage is explored through artistic practice, and an application process and implementation strategy for digital art innovation are proposed. Result: It is feasible to create NFT digital collections through artificial intelligence art to achieve the application scenarios of digital inheritance, innovation, cross-regional dissemination, and even industrialization of Zhuang Brocade in Guangxi. Conclusion: Artificial intelligence art creation can provide new opportunities for digital cultural dissemination and inheritance of Zhuang Brocade while reflecting its cultural connotations and characteristics, and ensure traceable development while ensuring intellectual property rights. It realizes the continuation and revival of the value of Zhuang Brocade in Guangxi, and provides a certain reference for the inheritance and development of other intangible cultural heritage in the current context of rapid media updates and iterations.

Risk Factors for Severity and Mortality of Patients Hospitalized for COVID-19 during the 3rd Wave of the Epidemic-Sao Tome and Principe

Rationale: In the literature, some risk factors for severity and mortality from COVID-19 have been indicated. However, these factors can change, depending on the characteristics of the population and health services. In this sense, longitudinal studies can be useful for understanding local realities and subsidizing health actions based on these realities. Objective: To analyze the risk factors for severity and death in hospitalized patients with COVID-19. Methods: A retrospective cohort of patients with COVID-19 hospitalized from August 1 to October 16, 2021 (3rd wave of the pandemic), notified by the Department of Epidemiological Surveillance of Sao Tome and Principe. We employed measures of strength of associations for the analysis of exposure risk factors. Results: We analyzed 110 hospitalized patients (31.8% severe-critical and 68.2% non-severe). The risk factors for severe forms of COVID-19 were: being aged ≥60 years (RR = 3.3), being male (RR = 2), having comorbidities (RR = 2) and the risk increases to 10-fold for multicomorbidities, with emphasis on obesity, neoplasia, skin-muscle-surgical infection, dementia and to some degree CVD. 62.9% of patients with severe forms of the disease were not vaccinated. Risk factors for death among hospitalized and severe/critical cases, respectively, were having comorbidities (RR = 8 and 2.4) multicomorbidities (RR = 10 and 2.8 for those with 2 comorbidities and RR = 33.3 and 4 for those with 3 or 4 comorbidities), especially diabetes, dementia, neoplasia, cutaneous-muscular infection, and obesity. Although CVD was not associated with risk factors for death, these were the most frequently found among the severely hospitalized and deaths. In addition, important risk factors associated with death were not using corticoids (RR = 3.3, 230-fold risk) and not using anticoagulants-heparin (RR = 1.3, 30% risk) more compared to the severe cases that did use them. Most of the patients who died (63.2%) were not vaccinated. Moreover, having only 1 dose of the vaccine was a risk factor 1.9 times more for death among all hospitalized patients, but in the severe cases, there was no association between the variable vaccination and death. Among those hospitalized with 2 doses, it was a 0.5-fold protective factor among those hospitalized. The Delta variant of Sarscov-2 was the one found among severe cases and deaths investigated by genetic sequencing, with more exuberant clinical features compared to the other 2 previous vaccinations. Conclusion: Being elderly, male and presenting comorbidities, mainly multicomorbidities were the main characteristics associated with severity of COVID-19. On the other hand, comorbidities, and even worse, multicomorbidities, hospitalization for respiratory failure, lowered level of consciousness, no use of corticoid and no use of anticoagulation in critically ill patients, and not having at least 2 doses of vaccine for covid-19, were characteristics associated with death by COVID-19. These results will help inform healthcare providers so that the best interventions can be implemented to improve outcomes for patients with COVID-19. Public health interventions must be carefully tailored and implemented in these susceptible groups to reduce the risk of mortality in patients with COVID-19 and then the risk of major complications. Intensive and regular follow-up is needed to detect early occurrences of clinical conditions.