EFFECT OF ACUPUNCTURE ON NEUROLOGICAL DEFECTS AND DAILY LIFE ABILITY IN PATIENTS WITH ACUTE CEREBRAL HEMORRHAGE

Objective: To observe the effect of acupuncture of Shuigou (GV 26), Neiguan (PC 6), Zusanli (ST 36), etc. on neurological defects and daily life ability in patients with acute cerebral hemorrhage. Methods: Fifty eight cases of acute cerebral hemorrhage patients were randomized into control group (n=28) and treatment group (n=30). Patients of two groups were both treated with intravenous infusion of Mannitol and other expectant medicines. In addition, patients of treatment group were also treated with acupuncture therapy, once daily and continuously for one month. Before and after treatment, the scores of neurological defects and daily life ability (Barthel Index) were given for assessing the therapeutic effect. Results: Following treatment, both scores of neurological defects of two groups decreased significantly (P<0.05), and the score of treatment group was strikingly lower than that of control group (P<0.05). After treatment, values of Barthel Index (BI) of two groups increased considerably in comparison with pre treatment (P<0.01), and the value of BI of treatment group was bigger than that of control group (P<0.05). Conclusion: Acupuncture can improve acute cerebral hemorrhage patients’ nervous function and daily life ability.

Health-related quality of life and the ability to perform activities of daily living: a cross-sectional study on 1079 war veterans with ankle-foot disorders

Background:The ankle-foot injuries are among the war-related injuries that cause many serious secondary problems for a lifetime.This nationwide study aimed to assess health-related quality of life and the ability to perform activities of daily living in veterans with ankle-foot injuries due to the Iran-Iraq war.Methods:A total of 1079 veterans with ankle-foot injuries were enrolled in a cross-sectional study from 2014 to 2016.Demographic characteristics,including age,gender,marital status,disability percent,educational level,employment and additional injuries,were collected.The ability to perform daily activities was assessed using the Barthel activities of daily living(ADL)and Lawton instrumental activities of daily living(IADL)Indexes.Physical and mental health-related quality of life(HRQOL)data were measured via the SF-36 subscales.The data were compared with those of bilateral lower limb amputees(BLLAs)and of the general Iranian population.Statistical analyses,including Pearson’s correlation coefficient,one-sample t-test and analysis of variance(ANOVA),were performed using SPSS16.0.A multiple linear regression model was used to determine the contribution of independent variables to the Physical Component Summary(PCS)and Mental Component Summary(MCS).Results:The highest and lowest scores were observed for mental health(48.93±20.69)and bodily pain(28.16±21.74),respectively.The mean scores of veterans with ankle-foot injuries on the SF-36 were significantly lower on all eight measures than those of the general Iranian male population and of the bilateral lower limb amputees(P<0.001).The mean scores of ADLs and IADLs were 83.9±16.3 and 5.3±2.0,respectively.The higher dependency in ADLs(P<0.001)and IADLs(P<0.001),the higher disability rate(P<0.001)and additional injury(P<0.001)were significant determinants of the PCS.ADL(P<0.001)and IADL(P<0.001)limitations,additional injury(P<0.001),history of hospitalization in the year preceding the study(P=0.007)and employment(P=0.001)were reported as determinants of the MCS.Conclusion:The results strongly suggest that veterans with ankle-foot injuries suffer from critically poor healthrelated quality of life.The main predicting factors of HRQOL were the disability to perform ADLs/IADLs,suffering two or more injuries,a history of hospitalization in the year preceding the study and unemployment.

Patient Life Experience and Activity of Daily Living before and after Total Knee Arthroplasty

Background: As the population ageing, more patients suffer from joint disease. Joint replacement surgery performed in Taiwan is about 10,000 to 20,000 cases yearly. Aims: The purpose of this study is to realize Total Knee Arthroplasty (TKA) patients’ views about life experiences and difficulty in daily life before and after the surgery. Methods: In this study, in-depth interview with interview guideline was used to analyze patients’ experience by using a qualitative research method, and questionnaires were used to collect quantity data. Results: 1) A total of 20 participants were recruited. Average age was 75.15 (SD = 6.468). Eighteen of the participants were female and the other two were male. The majority of participants indicated that their home facilities were convenient or very convenient. 2) Motivations of the participants to undergo TKA were joint pain, limited joint range of motion, and weakness in legs. Participants’ expectations after surgery were no more pain and ease in walking, and able to manage daily life. 3) Depending on the time after surgery, joint pain and walking ability had improved to some extent. The joint range of motion increased, but kneeling remained difficult, and the participants’ mood and exercise capacity were improved. Conclusions: The finding can be as a reference for clinical practitioner to provide preoperative education for total knee arthroplasty patients.

Relationship between activities of daily living and depression among older adults and the quality of life of family caregivers

Objective： The purposes of this study were to explore the associations of activities of daily living （ADL） and depression among older adults with family caregivers1 quality of life and provide evidence for improving family caregivers＇ quality of life.Methods： Older adults （n=395） and their family caregivers （n=395） were selected as participants. The ADL scale and Geriatric Depression Scale were used to assess ADL and depression among older adults, and the 36-Item Short Form Health Questionnaire （SF-36） was used to assess family caregivers1 quality of life. Descriptive statistics and multiple linear regression were used to analyze the data.Resslts： The older adults’ ADL and depression scores were 21 ±7 and 11 ±6, respectively. Approximately 69.9% of older adults had declining or severely impaired ADL, and 47.1% had mild or moderate-to-severe depression. Family caregivers＂ mean quality of life score was 529±100. There was a negative correlation of older adults＇ ADL and depression with caregivers＇ quality of life. The correlation coefficient between ADL and the SF-36 mental component summary score was stronger than it was with the SF-36 physical component summary score.Conclusions： The ADL and depression of older adults influenced family caregivers＇ quality of life. Psychological health deserves closer attention, especially that of caregivers of disabled older adults.

Botulinum toxin type A plus rehabilitative training for improving the motor function of the upper limbs and activities of daily life in patients with stroke and brain injury

BACKGROUND:Botulinum toxin type A(BTX-A)is mostly to be used to treat various diseases of motor disorders,whereas its effect on muscle spasm after stroke and brain injury needs further observation.OBJECTIVE:To observe the effect of BTX-A plus rehabilitative training on treating muscle spasm after stroke and brain injury.DESIGN:A randomized controlled observation.SETTINGS:Department of Rehabilitation,Department of Neurology and Department of Neurosurgery,the Second Hospital of Hebei Medical University.PARTICIPANTS:Sixty inpatients with brain injury and stroke were selected from the Department of Rehabilitation,Department of Neurology and Department of Neurosurgery,the Second Hospital of Hebei Medical University from January 2001 to August 2006.They were all confirmed by CT and MRI,and had obvious increase of spastic muscle strength in upper limbs,their Ashworth grades were grade 2 or above.The patients were randomly divided into treatment group(n=30)and control group(n=30).METHODS:①Patients in the treatment group undertook comprehensive rehabilitative trainings,and they were administrated with domestic BTX-A,which was provided by Lanzhou Institute of Biological Products,Ministry of Health(S10970037),and the muscles of flexion spasm were selected for upper limbs,20-25 IU for each site.②Patients in the treatment group were assessed before injection and at 1 and 2 weeks,1 and 3 months after injection respectively,and those in the control group were assessed at corresponding time points.The recovery of muscle spasm was assessed by modified Ashworth scale(MAS,grade 0-Ⅳ;Grade 0 for without increase of muscle strength;GradeⅣfor rigidity at passive flexion and extension);The recovery of motor function of the upper limbs was evaluated with Fugl-Meyer Assessment(FMA,total score was 226 points,including 100 for exercise,14 for balance,24 for sense,44 for joint motion,44 for pain and 66 for upper limb);The ADL were evaluated with Barthel index,the total score was 100 points,60 for mild dysfunction,60-41 for moderate dysfunction,<40 for severe dysfunction).MAIN OUTCOME MEASURES:Changes of MAS grade,FMA scores and Barthel index before and after BTX-A injection.RESULTS:All the 60 patients with brain injury and stroke were involved in the analysis of results.①FMA scores of upper limbs:The FMA score in the treatment group at 2 weeks after treatment was higher than that before treatment[(14.98±10.14),(13.10±9.28)points,P<0.05],whereas there was no significant difference at corresponding time point in the control group.The FMA scores at 1 and 3 months in the treatment group[(23.36±10.69),(35.36±11.36)points]were higher than those in the control group[(20.55±10.22),(30.33±10.96)points,P<0.01].②MAS grades of upper limbs:There were obviously fewer cases of gradeⅢin MAS at 2 weeks after treatment than before treatment in the treatment group(0,9 cases,P<0.05),whereas there was no obvious difference in the control group.There were obviously fewer cases of gradeⅢin MAS at 2 weeks and 1 month after treatment in the treatment group(0,0 case)than the control group(5,2 cases,P<0.01).③Barthel index of upper limbs:The Barthel index at 2 weeks after treatment was higher than that before treatment in the treatment group[(30.36±22.25),(28.22±26.21)points,P<0.05],whereas there was no significant difference in the control group.The Barthel indexes at 1 and 3 months after treatment in the treatment group were obviously higher than those in the control group[(20.55±10.22),(30.33±10.96)points,P<0.01].CONCLUSION:BTX-A has obvious efficacy on decreasing muscle tension after stroke and brain injury,and relieving muscle spasm;Meanwhile,the combination with rehabilitative training can effectively ameliorate the motor function of upper limbs and ADL of the patients.

The Relationship among Chronic Disease, Feeling-for-Their-Age, Sleep Quality, Health-Related Quality of Life and Activities of Daily Living of Community-Dwelling Persons over 55 Years of Age

Japan’s aging population rate is increasing and healthy life expectancy has decreases by 10 years shorter than average life expectancy. The aim of this study is to determine the relationship among chronic disease, sleep quality, health-related quality of life (HRQOL), and activities of daily living in people over 55 years old who live in the community. Subjects were 161 persons aged 57 to 90 years who were treated with chronic disease in the outpatient department of the A hospital. Exclusion criteria included patients with dementia, cancer and severe heart disease. The survey evaluation questionnaires included the Pittsburgh Sleep Quality Index (PSQI), HRQOL by Short-Form 8 Health Survey (SF-8), and activities of daily living. Variables associated with quality of sleep, HRQOL in univariate analysis with p < 0.05 were entered into multivariate analysis using logistic regression with a stepwise forward selection procedure to determine independent variables and their association with major causes. The logistic regression analysis was done using SPSS software and the post-hoc power of the study was estimated using G*power. The level of significance was set at p < 0.05. The risk factor of poor sleep quality was because of history of cancer [odds ratio (OR): 3.53, 95% confidence interval (CI): 1.06 - 11.77], and insomnia (OR: 3.25, 95% CI: 1.55 - 6.79). The risk factors of poor physical HRQOL were motor disease (OR: 2.62, 95% CI: 1.36 - 5.07), respiratory disease (OR: 3.24, 95% CI: 1.27 - 8.26) and having pain (OR: 11.71, 95% CI: 5.35 - 25.66). In addition, anemia was found to be a risk factor of poor mental HRQOL (OR: 4.87, 95% CI: 1.11 - 21.33). The feeling-for-their-body-age (OR: 0.30, 95% CI: 0.15-0.59) was as “younger than actual age” and advanced the risk factor of poor sleep quality. In addition, feeling-for-their-age (OR: 0.44, 95% CI: 0.21 - 0.92) resulted in reduced risk factor of poor physical HRQOL. The risk factor of poor sleep quality was due to a patient with history of cancer. The factor for good sleep quality and the good factor for physical HRQOL were indications of feeling younger than the actual age.

Disability and Quality of Life among Elderly Persons with Self-Reported Hearing Impairment: Report from the Ibadan Study of Aging

Background: Despite a high prevalence of hearing impairment (HI) among the elderly, the effect on their quality of life (QOL) has not been well studied in this environment. Aim: To determine the prevalence of disability and profile of QOL among elderly persons (aged ≥65 years) with HI. Design of Study: Cross-sectional. Setting: Eight contiguousYoruba-speaking states in Nigeria. Methods: Face-to-face interviews of respondents selected using a multi-stage, stratified area probability sampling of households;HI was based on self report and observer confirmation and the QOL was measured with the World Health Organization brief version (WHOQOL-Bref). Results: The prevalence of disability in Activities of Daily Living (ADL) was 35.4% while it was 10.1% in Instrumental ADL. Prevalence increased significantly with increasing age (P = 0.05). Disability in ADL (P = 0.01), poor family interaction (P = 0.01), poor community involvement (P = 0.01) cognitive impairment (P = 0.05) and poor report of overall health (P = 0.05) were significantly more common among the elderly with HI than those without. No significant differences were found in regard to current depression or the likelihood of experiencing verbal, physical or emotional abuses. Logistic regression analyses adjusting for age, sex, chronic medical conditions and disability confirmed the salient effect of HI on the decrement in the physical domains (P = 0.05). Conclusion: HI is associated with high prevalence of disability and has adverse effect on the quality of life. This observation strengthens the need for hearing rehabilitation in the policy formulation on the care of the elderly in resource-poor settings.

Effects of physical activity by the teach-back educational method on the physical ability and quality of life in hemodialysis patients:a clinical trial

Objective:To determine the effect of physical activity by using the teach-back educational method on hemodialysis patients’quality of life(QOL)and physical ability.Methods:This is a single-blind clinical trial study involving a control group.A total of 90 patients who admitted to the dialysis centers of Beheshti and Besat hospitals in Hamadan were selected using a convenience sampling method and were randomly assigned to intervention(n=45)and control(n=45)groups.Data were collected using a demographic information checklist,a kidney disease QOL questionnaire,and a 6-minute-walk distance(6MWD)checklist.The patients’QOL questionnaire was completed,and the 6MWD was recorded before and at the end of the 2nd,4th,6th,8th,and 12th weeks of the intervention.In the intervention group,the patients were taught to perform physical activities with Pilates stretches in different resistances using the teach-back educational method during dialysis sessions for 12 weeks.Data were analyzed by using the independent t-test and chi-square test using SPSS-22 software.Results:Before the intervention,no differences were observed between the experimental and control groups in terms of demographic characteristics,QOL,and physical ability(P>0.05).The physical ability and QOL levels of patients exercising in the test group were higher than those in the control group after the intervention(P<0.05).Based on the results,the 2 groups significantly differed with regard to the scores of various dimensions of QOL and physical ability after the intervention(P<0.05).Conclusions:Physical activity by using the teach-back method can effectively increase physical ability and improve QOL of hemodialysis patients.Therefore,the recommendations and inclusion of exercise in the dialysis care plan can effectively promote patients’health.

The following-up observation of ability of living after senile fracture

Objective To investigate the effect of senile f racture on ability of daily life.Method Carry out effective surgery in early time and encourage early out-of-bed activity to prevent secondary aging under th e monitor of internal medicine.Result Follow up 208patients for 1-3years(mean 1.8years),13patients(6.25%)were dead,153(73.55%)resumed the ability of independent l ife,32(15.38%)resumed the ability partly,10(4.8%)patients lost ability of life.Conclusion For the aged fracture,the ability of living could be improved by early surgery,reducing complications and active functional training of lowe r limbs under the monitor of internal medicine.

Health-Related Quality of Life of Children and Adolescents with Juvenile Idiopathic Arthritis in Western Saudi Arabia

Objectives: To evaluate the effect of Juvenile Idiopathic Rheumatoid Ar-thritis (JIA) on the health-related quality of life (HRQOL) in Saudi children. Methods: A cross-sectional study was conducted in a tertiary hospital in Jeddah, Saudi Arabia to evaluate the HRQOL of children aged ≤ 18 years who had JIA using the childhood health assessment questionnaire modified for Arab children (CHAQ-MAC). Such questionnaire investigates 34 activities of daily life (ADL) classified into 8 life domains. Children or their parents were invited for face-to-face interview, and a phone interview was done for patients who missed their appointments during the period between February and July 2017. A statistical model was used to calculate a total CHAQ.MAC score (range = 0 - 33;Cronbach’s alpha = 0.966);with higher values indicating poorer HRQOL. Results: Of a total of 44 children (male ratio = 0.63;mean ± SD age = 9.95 ± 5.44), Systemic-onset JIA was the most frequent type (27.3%), followed by polyarticular (15.9%) and oligoarticular (13.6%). Pain was reported among 43.2% (frequently in the knee, in 27.3%) whereas morning stiffness was reported in 20.5%. The mean CHAQ.MAC score = 2.89 (75th centile = 3.00). With respect of ADLs, up to 22.7% of the children complained of difficulty;and 31.8% reported a difficulty in at least one of the 34 investigated ADLs. With respect of the life domain, children reported difficulties for activities (27.3%), dressing & grooming and hygiene (13.6%), and eating (6.82%). According to the life domain, 4.5% to 13.6% of the children needed help to execute the related ADLs and up to 9.1% used aids or devices. Poor HRQOL was associated with articular pain (p = 0.003) and specific medication (p = 0.043). Con-clusion: Children with arthralgia and those on specific treatment are at higher risk of impaired QOL, which emphasizes the need for systematic screening for treatment adverse effects and joint pain and implementation of efficient management to improve HRQOL.

Intervention effect of neuromuscular electrical stimulation on ICU acquired weakness: A meta-analysis

Objective:The early use of neuromuscular electrical stimulation(NMES)to prevent intensive care unit-acquired weakness(ICU-AW)in critical patients is still a controversial topic.We conducted a systematic review to clarify the effectiveness of NMES in preventing ICU-AW.Methods:The Cochrane Library,PubMed,EMBASE,MEDUNE,Web of Science,Ovid,CNKI,Wanfang,VIP,China Biology Medicine disc(CBMdisc)and other databases were searched for randomized controlled trials on the influence of NMES on ICU-AW.The studies were selected according to the inclusion and exclusion criteria.After data and quality were evaluated,a meta-analysis was performed by RevMan 5.3 software.Results:A total of 11 randomized controlled trials with 576 patients were included.The meta-analysis results showed that NMES can improve muscle strength[MD=1.78,95%CI(0.44,3.12,P=0.009);shorten the mechanical ventilation(MV)time[SMD=-0.65,95%CI(-1.03,-0.27,P=0.001],ICU length of stay[MD=-3.41,95%CI(-4.58,-4.24),P<0.001],and total length of stay[MD=-3.97,95%CI(-6.89,-1.06,P=0.008];improve the ability of patients to perform activities of daily living[SMD=0.9,95%CI(0.45,1.35),P=0.001];and increase walking distance[MD=239.03,95%CI(179.22298.85),P<0.001].However,there is no evidence indicating that NMES can improve the functional status of ICU patients during hospitalization,promote the early awakening of patients or reduce mortality(P>0.05).Conclusion:Early implementation of the NMES intervention in ICU patients can prevent ICU-AW and improve their quality of life by enhancing their muscle strength and shortening the MV duration,length of stay in the ICU and total length of stay in the hospital.

Application of a paraplegic gait orthosis in thoracolumbar spinal cord injury

Paraplegic gait orthosis has been shown to help paraplegic patients stand and walk, although this method cannot be individualized for patients with different spinal cord injuries and functional recovery of the lower extremities. There is, however, a great need to develop individualized paraplegic orthosis to improve overall quality of life for paraplegic patients. In the present study, 36 spinal cord（below T4） injury patients were equally and randomly divided into control and observation groups. The control group received systematic rehabilitation training, including maintenance of joint range of motion, residual muscle strength training, standing training, balance training, and functional electrical stimulation. The observation group received an individualized paraplegic locomotion brace and functional training according to the various spinal cord injury levels and muscle strength based on comprehensive systematic rehabilitation training. After 3 months of rehabilitation training, the observation group achieved therapeutic locomotion in 8 cases, family-based locomotion in 7 cases, and community-based locomotion in 3 cases. However, locomotion was not achieved in any of the control group patients. These findings suggest that individualized paraplegic braces significantly improve activity of daily living and locomotion in patients with thoracolumbar spinal cord injury.

Clinical value of ankle flexion and extension exercises combined with a psychological intervention in knee osteoarthritis

BACKGROUND Considering the limited effectiveness of clinical interventions for knee osteoarthritis(KOA),it is necessary to continue to explore appropriate and effective treatment strategies to improve the condition of KOA patients.AIM To clarify the influence of ankle flexion and extension exercises combined with a psychological intervention on the psychological status and activities of daily living(ADLs)of patients with KOA.METHODS The research participants were 116 KOA patients admitted to The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine between May 2019 and May 2022,including 54 patients receiving routine treatment,care and psychological intervention(control group)and 62 patients additionally treated with ankle flexion and extension exercises(research group).The two groups were comparatively analyzed in terms of psychological status(Self-rating Anxiety/Depression Scale,SDS/SAS),ADLs,knee joint function(Lysholm Knee Scoring Scale),pain(Visual Analog Scale,VAS),fatigue(Multidimensional Fatigue Inventory,MFI),and quality of life(QoL;Short-Form 36 Item Health Survey,SF-36).RESULTS After evaluation,it was found that the postinterventional SDS,SAS,VAS,and MFI scores in the research group were significantly reduced compared with the baseline(before the intervention)values and those of the control group,while the postinterventional Lysholm,ADL and SF-36 scores were markedly elevated.CONCLUSION Therefore,ankle flexion and extension exercises are highly effective in easing negative psychological status,enhancing ADLs,daily living ability,knee joint function and QoL,and relieving pain and fatigue in KOA patients,thus warranting clinical promotion.

Smart Devices Based Multisensory Approach for Complex Human Activity Recognition

Sensors based Human Activity Recognition(HAR)have numerous applications in eHeath,sports,fitness assessments,ambient assisted living(AAL),human-computer interaction and many more.The human physical activity can be monitored by using wearable sensors or external devices.The usage of external devices has disadvantages in terms of cost,hardware installation,storage,computational time and lighting conditions dependencies.Therefore,most of the researchers used smart devices like smart phones,smart bands and watches which contain various sensors like accelerometer,gyroscope,GPS etc.,and adequate processing capabilities.For the task of recognition,human activities can be broadly categorized as basic and complex human activities.Recognition of complex activities have received very less attention of researchers due to difficulty of problem by using either smart phones or smart watches.Other reasons include lack of sensor-based labeled dataset having several complex human daily life activities.Some of the researchers have worked on the smart phone’s inertial sensors to perform human activity recognition,whereas a few of them used both pocket and wrist positions.In this research,we have proposed a novel framework which is capable to recognize both basic and complex human activities using builtin-sensors of smart phone and smart watch.We have considered 25 physical activities,including 20 complex ones,using smart device’s built-in sensors.To the best of our knowledge,the existing literature consider only up to 15 activities of daily life.

Non-motor signs and symptoms in Parkinson’s disease

Motor symptoms are cardinal clinical features of Parkinson’s disease (PD). Progress in drug therapy and rehabilitation has been presenting beneficial effect for motor symptoms. However, non-motor symptoms and signs in PD have been accumulated growing attentions and its amelioration may also give beneficial effect for PD patients’ and their care givers’ quality of life. In this mini-review, I overviewed non-motor symptoms and signs in PD.

解郁疏肝汤联合针灸疗法治疗缺血性脑卒中的疗效及对血清sLOX-1、omentin-1的影响

【目的】探讨解郁疏肝汤(由柴胡、枳壳、石菖蒲、郁金、香附、陈皮、桃仁、红花、半夏等中药组成)联合针灸疗法治疗缺血性脑卒中患者的临床疗效及其对血清可溶性凝集素样氧化低密度脂蛋白受体1(sLOX-1)、网膜素1(omentin-1)的影响。【方法】将106例缺血性脑卒中患者随机分为观察组和对照组,每组各53例。对照组给予溶栓及常规神经内科治疗,观察组在对照组的基础上加用解郁疏肝汤联合针灸疗法(取穴:哑门、合谷、中脘、劳宫、太溪、足三里、三阴交、涌泉穴、环跳等)治疗,疗程为2周。观察2组患者治疗前后简易智力状态检查量表(MMSE)评分、Barthel指数评分及血清C反应蛋白(CRP)、同型半胱氨酸(Hcy)、D-二聚体(D-D)、sLOX-1、omentin-1水平变化情况,并于溶栓治疗30 d后评价2组患者的临床疗效。【结果】(1)溶栓治疗30 d后,观察组的总有效率为94.34%(50/53),对照组为81.13%(43/53),组间比较,观察组的疗效明显优于对照组(P<0.05)。(2)治疗后,2组患者血清CRP、Hcy、D-D水平均较治疗前明显降低(P<0.05),且观察组对血清CRP、Hcy、D-D水平的降低作用均明显优于对照组(P<0.01)。(3)溶栓后3 d和7 d,2组患者的24 h舒张压、24 h收缩压、白天舒张压、白天收缩压、夜晚舒张压、夜晚收缩压均较溶栓后24 h降低(P<0.05),且溶栓后7 d又均较溶栓后3 d降低(P<0.05);组间比较,观察组在溶栓后3 d和7 d对各项24 h动态血压的降低作用均明显优于对照组(P<0.05)。(4)治疗后,2组患者的MMSE评分和Barthel指数评分均较治疗前升高(P<0.05),且观察组对MMSE评分和Barthel指数评分的升高作用均明显优于对照组(P<0.01)。(5)治疗后,2组患者血清sLOX-1水平降低(P<0.05),血清omentin-1水平升高(P<0.05),且观察组对血清sLOX-1水平的降低作用及对血清omentin-1水平的升高作用均明显优于对照组(P<0.01)。【结论】解郁疏肝汤联合针灸疗法治疗缺血性脑卒中患者疗效确切,可较好地改善患者神经功能缺损,调降血清sLOX-1水平,调升血清omentin-1水平,进而促进患者认知功能和日常活动能力的恢复。

后外侧入路与改良Hardinge入路在全髋关节置换术中的应用比较

目的比较后外侧入路与改良Hardinge入路在全髋关节置换术(THA)中的应用效果。方法选取2019年7月—2022年6月于新泰市人民医院行THA治疗的89例患者作为研究对象,对照组(44例)采用后外侧入路进行THA手术,观察组(45例)采用改良Hardinge入路进行THA手术。比较两组术中与术后情况(手术操作时间、出血量,以及引流量、离床时间、住院时间)、Harris髋关节功能量表(HHS)评分、Barthel指数(BI指数)评分、生活质量综合评定量表(GQOLI-74)评分,以及术后并发症情况。结果观察组、对照组手术出血量分别为(255.50±25.85)、(326.47±28.42)mL,引流量分别为(120.45±25.65)、(165.00±23.44)mL,观察组手术出血量、引流量低于对照组(P均<0.05)。观察组、对照组离床时间分别为(3.92±0.46)、(4.06±0.50)d,住院时间分别为(12.00±2.32)、(15.02±3.00)d,观察组离床时间、住院时间短于对照组(P均<0.05)。两组术后6个月时HHS量表、BI指数、GQOLI-74量表评分比较差异均无统计学意义。观察组术后并发症发生率(4.44%)较对照组(22.73%)低(P<0.05)。结论采用后外侧入路与改良Hardinge入路进行THA手术均能够改善患者的髋关节功能,提高其日常生活活动能力与生活质量,但与后外侧入路相比,改良Hardinge入路有效减少了术中出血量与术后引流量,降低术后并发症风险,加快康复进程,具有临床应用与推广价值。

左归丸联合丁苯酞佐治帕金森病轻度认知障碍疗效评价

目的探讨左归丸联合丁苯酞佐治帕金森病轻度认知障碍的临床疗效。方法选取医院2023年1月至3月收治的帕金森病轻度认知障碍患者80例,按随机数字表法分为观察组和对照组,各40例。两组患者均予常规抗帕金森病西药治疗,并予丁苯酞软胶囊口服,观察组患者加服左归丸。两组均连续治疗8周。结果观察组总有效率为90.00%,显著高于对照组的70.00%(P<0.05)。治疗后,观察组患者的腰膝酸软、胁肋疼痛、头晕头痛中医证候积分均显著低于对照组(P<0.05);观察组患者的沉默信息调节因子1(SIRT1)蛋白表达水平显著高于对照组,核因子κB(NF-κB)蛋白表达水平显著低于对照组(P<0.05);观察组患者的蒙特利尔认知评估量表(MoCA)、简易精神状态量表(MMSE)及日常生活活动能力(ADL)量表评分均显著高于对照组(P<0.05);观察组患者的统一帕金森病评定量表(UPDRS)评分显著低于对照组(P<0.05)。观察组与对照组不良反应发生率相当(5.00%比2.50%,P>0.05)。结论常规抗帕金森病治疗基础上佐以左归丸联合丁苯酞,可降低帕金森病轻度认知障碍患者的中医证候积分,改善SIRT1及NF-κB蛋白表达水平,提升认知功能及日常生活能力。

SFBC联合TOT对急性脑卒中后偏瘫患者肢体功能康复及ADL能力的影响

目的探究焦点解决短期咨询(SFBC)联合任务导向性训练(TOT)对急性脑卒中后偏瘫患者肢体功能康复及日常生活活动(ADL)能力的影响。方法选取2021年1月至2023年1月于潜江市中心医院康复医学科收治的101例急性脑卒中后偏瘫患者为研究对象,采用随机数表法将其分为观察组(51例)和对照组(50例)。对照组采用常规TOT训练方法,观察组采用SFBC联合TOT训练方法。比较两组患者心理状况[焦虑自评量表(SAS)和抑郁自评量表(SDS)]、Fugl-Meyer运动功能评分量表(FMA)及Barthel指数(BI)。结果干预前两组心理状况、FMA评分及BI评分比较,差异无统计学意义(P>0.05),干预2个月后观察组SAS、SDS评分显著低于对照组,差异有统计学意义(P<0.05),上肢运动功能量表(FMA-UE)、下肢运动功能量表(FMA-LE)、BI评分均显著高于对照组,差异有统计学意义(P<0.05)。结论SFBC联合TOT的康复治疗训练可以改善急性脑卒中后偏瘫患者心理状况,提高患者肢体康复功能及ADL能力。

PROKIN Systems平衡测试与训练系统对脑卒中偏瘫患者平衡功能及步行速度的影响

目的 探讨PROKIN Systems平衡测试与训练系统在脑卒中偏瘫患者中的应用价值。方法 随机选取2019年5月—2022年5月息烽县人民医院康复疼痛科收治的60例脑卒中偏瘫患者为研究对象,按随机数表法分为对照组和观察组,各30例。对照组采用常规康复训练,观察组采用PROKIN Systems平衡测试与训练系统进行训练,两组均训练4周。对比分析两组平衡功能、步行速度、步行功能、日常生活活动能力。结果 训练后,观察组Berg平衡量表(Berg Balance Scale,BBS)评分[(40.17±3.52)分]、功能性步行分级量表(Functional Ambulation Category,FAC)评分[(3.46±0.30)分]、日常生活活动能力量表(Activities of Daily Living Scale,ADL)中转移评分[(10.94±1.32)分]、行走评分[(19.23±2.85)分]、括约肌控制评分[(8.09±0.91)分]、自理能力评分[(34.95±3.64)分]及总分[(73.21±5.43)分]均高于对照组,步行速度[(57.34±6.81)cm/s]快于对照组,差异有统计学意义(P<0.05)。结论 PROKIN Systems平衡测试与训练系统能够提高脑卒中偏瘫患者平衡与步行功能,加快其步行速度,促使其日常生活活动能力恢复正常。