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Assessment of Monitor Units and Gamma Pass Rate for 6 MV and Flattening Filter Free (FFF) Beams in Volumetric Modulated Arc Therapy (VMAT)
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作者 Kwame Anokye Amoabeng Anne Beate Langeland Marthinsen +4 位作者 Francis Hasford Samuel Nii Adu Tagoe Evelyn Anaafi Mark Pokoo-Aikins Theresa Bebaaku Dery 《International Journal of Medical Physics, Clinical Engineering and Radiation Oncology》 2023年第1期1-8,共8页
Background: In linear accelerators, the treatment field’s uniform intensity is achieved by including a flattening filter in the beam. However, to produce more conformal dose distributions, contemporary radiotherapy p... Background: In linear accelerators, the treatment field’s uniform intensity is achieved by including a flattening filter in the beam. However, to produce more conformal dose distributions, contemporary radiotherapy practice now frequently uses fluence and aperture modifying techniques, such as volumetric modulated arc therapy. In these circumstances, the flattening filter in the beam manufacturing process is no longer required. It is therefore necessary to compare the monitor units of 6 MV and flattening filter free plans and how it influences the gamma pass rates to determine which is best for treating cervical cancer with pelvic lymph node metastasis. Methods: VMAT plans for fifteen patients with cervical cancer with pathological pelvic lymph node metastasis were included in this study. Each patient had two VMAT plans using conventional 6 MV beam with flattening filter and one with flattening filter free beam (FFF). The VMAT plans were made using two arcs, and then recalculated to give the planned dose distribution to the detectors in a Delta4 phantom. The VMAT plans were irradiated on the Delta4 phantom using an Elekta linear accelerator (6 MV). Results: The mean monitor unit for the 6 MV plans was 506.3 MU and a standard deviation of 48.6 while that of the FFF plans had a mean MU of 701.5 with a standard deviation of 87.6. The total monitor units (MUs) for the FFF plans were significantly greater than the 6 MV plans (p = 6.1 × 10<sup>-5</sup>). Conclusion: Flattening filter free (FFF) plans require more numbers of monitor units in comparison to conventional 6 MV filtered beams for external radiation of cervical cancer with pelvic lymph nodes involvement. 展开更多
关键词 Monitor units Gamma Pass rate Flattening Filter Free Multileaf Collimator
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Derivation of Plastic Work Rate Done per Unit Volume for Mean Yield Criterion and Its Application 被引量:8
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作者 Dewen ZHAO Yingjie XIE +1 位作者 Xiaowen WANG Xianghua LIU 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2005年第4期433-436,共4页
In Haigh Westergaard stress space linear combination of twin shear stress and Tresca yield functions is called the mean yield (MY) criterion. The mathematical relationship of the criterion and its plastic work rate ... In Haigh Westergaard stress space linear combination of twin shear stress and Tresca yield functions is called the mean yield (MY) criterion. The mathematical relationship of the criterion and its plastic work rate done per unit volume were derived. A generalized worked example of slab forging was analyzed by the criterion and its corresponding plastic work rate done per unit volume. Then, the precision of the solution was compared with those by Mises and Twin shear stress yield criterions, respectively. It turned out that the calculated results by MY criterion were in good agreement with those by Mises criterion. 展开更多
关键词 Mean yield criterion Plastic work rate done per unit volume Functional linearization Slab forging
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Cleaning of two mirrors in the first mirror unit using radiofrequency capacitively coupled plasma
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作者 Chenxue WANG Rong YAN +5 位作者 Yuming LIU Su XU Lei MU Wei ZHENG Rui DING Junling CHEN 《Plasma Science and Technology》 SCIE EI CAS CSCD 2024年第9期165-171,共7页
First mirror(FM)cleaning,using radio frequency(RF)plasma,has been proposed to recover FM reflectivity in nuclear fusion reactors such as the International Thermonuclear Experimental Reactor(ITER).To investigate the in... First mirror(FM)cleaning,using radio frequency(RF)plasma,has been proposed to recover FM reflectivity in nuclear fusion reactors such as the International Thermonuclear Experimental Reactor(ITER).To investigate the influence of simultaneous cleaning of two mirrors on mirror cleaning efficiency and uniformity,experiments involving single-mirror cleaning and dual-mirror cleaning were conducted using RF capacitively coupled plasma in the laboratory.For the test and simultaneous cleaning of two mirrors,the FM and second mirror(SM),both measuring 110 mm×80 mm,were placed inside the first mirror unit(FMU).They were composed of 16 mirror samples,each with a dimension of 27.5 mm×20 mm.These mirror samples consist of a titanium-zirconium-molybdenum alloy substrate,a 500 nm Mo intermediate layer and a 30 nm Al_(2)O_(3) surface coating as a proxy for Be impurities.The cleaning of a single first mirror(SFM)and the simultaneous cleaning of the FM and SM(DFM and DSM)lasted for 9 h using Ar plasma at a pressure of 1 Pa.The total reflectivity of mirror samples on the DSM did not fully recover and varied with location,with a self-bias of−140 V.With a self-bias of−300 V,the total reflectivity of mirror samples on the SFM and DFM was fully recovered.The energy dispersive spectrometer results demonstrated that the Al_(2)O_(3) coating had been completely removed from these mirror samples.However,the mass loss of each mirror sample on the SFM and DFM before and after cleaning varied depending on its location,with higher mass loss observed for mirror samples located in the corners and lower loss for those in the center.Compared with SM cleaning,the simultaneous cleaning of two mirrors reduced the difference between the highest and lowest mass loss.Furthermore,this mass loss for the mirror samples of the DFM facing the DSM was increased.This indicated that mirror samples cleaned face to face in the FMU simultaneously could influence each other,highlighting the need for special attention in future studies. 展开更多
关键词 first mirror unit dual-mirror cleaning REFLECTIVITY sputtering rate
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Study on Hydrogen Storage Properties,Anti-Oxide Ability and Rate Limiting Step of ZrCr-Based Alloy after Introducing Cobalt as Additive
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作者 Dongfang Huang Peng Lv +2 位作者 Changlin Zhong Xingsheng Zhou Zhichen Liu 《Journal of Renewable Materials》 SCIE EI 2023年第3期1383-1400,共18页
In this work,the microstructure,hydrogen storage properties,anti-oxide ability and rate limiting step of Zr(Cr_(1−x)Co_(x))_(2)(x=0,0.2,0.4 and 0.6)alloys have been investigated.After studying the crystal structure,we... In this work,the microstructure,hydrogen storage properties,anti-oxide ability and rate limiting step of Zr(Cr_(1−x)Co_(x))_(2)(x=0,0.2,0.4 and 0.6)alloys have been investigated.After studying the crystal structure,we found that all alloy samples could show C14-type phase but the alloy sample x=0 could also show a small amount of Cr phase.Rietveld fitting showed that lattice parameter and unit cell volume of C14-type phase decreased with increasing x.After further research,it was clear that the first hydrogen absorption capacity decreased with increasing x.But introducing more Co content had a positive influence on the effective hydrogen storage capacity and cyclic hydrogen absorption and desorption properties of the alloy sample.We also found that adding Co to ZrCr_(2)alloy could improve its anti-oxide ability.In addition to this,the rate limiting step model was also studied. 展开更多
关键词 ZrCr_(2)alloy first hydrogenation anti-oxide ability rate limiting step cyclic hydrogen absorption and desorption properties
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Cost Effective Operating Strategy for Unit Commitment and Economic Dispatch of Thermal Power Plants with Cubic Cost Functions Using TLBO Algorithm
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作者 E. B. Elanchezhian S. Subramanian S. Ganesan 《Journal of Power and Energy Engineering》 2015年第6期20-30,共11页
This paper deals with a Unit Commitment (UC) problem of a power plant aimed to find the optimal scheduling of the generating units involving cubic cost functions. The problem has non convex generator characteristics, ... This paper deals with a Unit Commitment (UC) problem of a power plant aimed to find the optimal scheduling of the generating units involving cubic cost functions. The problem has non convex generator characteristics, which makes it very hard to handle the corresponding mathematical models. However, Teaching Learning Based Optimization (TLBO) has reached a high efficiency, in terms of solution accuracy and computing time for such non convex problems. Hence, TLBO is applied for scheduling of generators with higher order cost characteristics, and turns out to be computationally solvable. In particular, we represent a model that takes into account the accurate higher order generator cost functions along with ramp limits, and turns to be more general and efficient than those available in the literature. The behavior of the model is analyzed through proposed technique on modified IEEE-24 bus system. 展开更多
关键词 CUBIC COST FUNCTIONS RAMP rate TEACHING Learning Based Optimization unit COMMITMENT
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Effect of dynamic loading conditions on the dynamic performance of MP1 energy-absorbing rockbolts:Insight from laboratory drop test 被引量:3
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作者 Jinfu Lou Fuqiang Gao +2 位作者 Jianzhong Li Guiyang Yuan Mostafa Sharifzadeh 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2023年第2期215-231,共17页
Energy-absorbing rockbolts have been widely adopted in burst-prone excavation support, and their serviceability is closely related to the frequency and magnitude of seismic events. In this research, the splittube drop... Energy-absorbing rockbolts have been widely adopted in burst-prone excavation support, and their serviceability is closely related to the frequency and magnitude of seismic events. In this research, the splittube drop test with varying impact energy was conducted to reproduce the dynamic performance of MP1rockbolts under a wide range of seismic event magnitudes. The test results showed that the impact process could be subdivided into four distinct stages, i.e. mobilization, strain hardening, plastic flow(ductile), and rebound stage, of which strain hardening and plastic flow are the primary energy absorbing stages. As the impact energy per drop increases from 8.1 to 46.7 k J, the strain rate of the shank varies between 1.20 and 2.70 s^(-1), and the average impact load is between 240 and 270kN, which may be considered as constant. The MP1 rockbolt has a cumulative maximum energy absorption(CMEA) of 31.9–40.0 k J/m, with an average of 35.0 k J/m, and the elongation rate is 11.4%–14.7%, with an average of 12.7%, both of which are negatively correlated with the impact energy per drop. Regression analysis shows that energy absorption and shank elongation, as well as momentum input and impact duration,conform to the linear relationship. The complete dynamic capacity envelope of MP1 rockbolts is proposed, which reflects the dynamic bearing capacity, elongation, and distinct stages. This study is helpful to better understand the dynamic characteristics of energy-absorbing rockbolts and assist design engineers in robust reinforcement systems design to mitigate rockburst damage in seismically active underground excavations. 展开更多
关键词 Energy-absorbing rockbolt Dynamic performance Drop test Residual elastic energy(REE) Energy absorption rate(EAR) Dynamic capacity envelope
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Energy absorption characteristics of novel high-strength and hightoughness steels used for rock support 被引量:1
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作者 Ding Wang Manchao He +3 位作者 Liangjiu Jia Xiaoming Sun Min Xia Xuchun Wang 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2023年第6期1441-1456,共16页
Nowadays,the development of novel metallic materials for rock support have attracted research interests since they can significantly improve the deformation and energy absorption capacities of rock bolts.Although prev... Nowadays,the development of novel metallic materials for rock support have attracted research interests since they can significantly improve the deformation and energy absorption capacities of rock bolts.Although previous studies proved the importance and mechanical advantages of utilizing high-strength and high-toughness(HSHT)steels in rock support,there is no systematic analysis to reveal the essential energy absorption parameter and the guidelines for further development of metallic rock support materials.This paper analyzes the energy absorption characteristics of novel HSHT steels(negative Poisson’s ratio(NPR)and twinning-induced plasticity(TWIP)steels)in comparison with conventional rock support materials.A physically based crystal plasticity(CP)model was set up and calibrated to study the effect of strain hardening rate(SHR).Meanwhile,the roles of underlying physical mechanisms,i.e.the dislocation density and twin volume fraction,were studied.The results show that the improvement of energy absorption density(EAD)is essential for further development of rock support materials,besides the increase of energy absorption rate(EAR)for previous development of conventional rock support materials.The increase of EAD requires increases of both strength and deformation capacity of materials.For HSHT steels,the decrease of SHR has a positive effect on the improvement of EAD.In addition,the increase of EAD is followed by the increase of twin volume fraction and the decrease of plastic Poisson’s ratio which can promote deformation plasticity of materials.Meanwhile,the increase of EAR is correlated with the accumulation of dislocation density,which can increase the strength of materials.This paper provides the theoretical basis and guidelines for developing rock support materials in deep underground engineering and other related fields. 展开更多
关键词 Rock support Steel Energy absorption Strain hardening rate(SHR) Crystal plasticity(CP)
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Effects of acute kidney injury on acute pancreatitis patients’ survival rate in intensive care unit: A retrospective study 被引量:11
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作者 Ni Shi Guo-Dong Sun +16 位作者 Yuan-Yuan Ji Ying Wang Yu-Cheng Zhu Wan-Qiu Xie Na-Na Li Qiu-Yuan Han Zhi-Dong Qi Rui Huang Ming Li Zhen-Yu Yang Jun-Bo Zheng Xing Zhang Qing-Qing Dai Gui-Ying Hou Yan-Song Liu Hong-Liang Wang Yang Gao 《World Journal of Gastroenterology》 SCIE CAS 2021年第38期6453-6464,共12页
BACKGROUND Acute kidney injury(AKI)is one of the most common acute pancreatitis(AP)-associated complications that has a significant effect on AP,but the factors affecting the AP patients’survival rate remains unclear... BACKGROUND Acute kidney injury(AKI)is one of the most common acute pancreatitis(AP)-associated complications that has a significant effect on AP,but the factors affecting the AP patients’survival rate remains unclear.AIM To assess the influences of AKI on the survival rate in AP patients.METHODS A total of 139 AP patients were included in this retrospective study.Patients were divided into AKI group(n=72)and non-AKI group(n=67)according to the occurrence of AKI.Data were collected from medical records of hospitalized patients.Then,these data were compared between the two groups and further analysis was performed.RESULTS AKI is more likely to occur in male AP patients(P=0.009).AP patients in AKI group exhibited a significantly higher acute physiologic assessment and chronic health evaluation II score,higher Sequential Organ Failure Assessment score,lower Glasgow Coma Scale score,and higher demand for mechanical ventilation,infusion of vasopressors,and renal replacement therapy than AP patients in non-AKI group(P<0.01,P<0.01,P=0.01,P=0.001,P<0.01,P<0.01,respectively).Significant differences were noted in dose of norepinephrine and adrenaline,duration of mechanical ventilation,maximum and mean values of intra-peritoneal pressure(IPP),maximum and mean values of procalcitonin,maximum and mean serum levels of creatinine,minimum platelet count,and length of hospitalization.Among AP patients with AKI,the survival rate of surgical intensive care unit and in-hospital were only 23%and 21%of the corresponding rates in AP patients without AKI,respectively.The factors that influenced the AP patients’survival rate included body mass index(BMI),mean values of IPP,minimum platelet count,and hospital day,of which mean values of IPP showed the greatest impact.CONCLUSION AP patients with AKI had a lower survival rate and worse relevant clinical outcomes than AP patients without AKI,which necessitates further attention to AP patients with AKI in surgical intensive care unit. 展开更多
关键词 Acute kidney injury Acute pancreatitis Surgical intensive care unit Survival rate Risk factors Intra-peritoneal pressure
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Combination of a biopharmaceutic classification system and physiologically based pharmacokinetic models to predict absorption properties of baicalein in vitro and in vivo 被引量:2
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作者 Yang Liu Jing Sun +5 位作者 Linying Zhong Yu Li A Na Er Tong Li Le Yang Ling Dong 《Journal of Traditional Chinese Medical Sciences》 2021年第3期238-247,共10页
Objective: To determine the in vitro and in vivo absorption properties of active ingredients of the Chinese medicine, baicalein, to enrich mechanistic understanding of oral drug absorption.Methods: The Biopharmaceutic... Objective: To determine the in vitro and in vivo absorption properties of active ingredients of the Chinese medicine, baicalein, to enrich mechanistic understanding of oral drug absorption.Methods: The Biopharmaceutic Classification System(BCS) category was determined using equilibrium solubility, intrinsic dissolution rate, and intestinal permeability to evaluate intestinal absorption mechanisms of baicalein in rats in vitro. Physiologically based pharmacokinetic(PBPK) model commercial software GastroPlus~(TM) was used to predict oral absorption of baicalein in vivo.Results: Based on equilibrium solubility, intrinsic dissolution rate, and permeability values of main absorptive segments in the duodenum, jejunum, and ileum, baicalein was classified as a drug with low solubility and high permeability. Intestinal perfusion with venous sampling(IPVS) revealed that baicalein was extensively metabolized in the body, which corresponded to the low bioavailability predicted by the PBPK model. Further, the PBPK model predicted the key indicators of BCS, leading to reclassification as BCS-II. Predicted values of peak plasma concentration of the drug(C_(max)) and area under the curve(AUC)fell within two times of the error of the measured results, highlighting the superior prediction of absorption of baicalein in rats, beagles, and humans. The PBPK model supported in vitro and in vivo evidence and provided excellent prediction for this BCS class II drug.Conclusion: BCS and PBPK are complementary methods that enable comprehensive research of BCS parameters, intestinal absorption rate, metabolism, prediction of human absorption fraction and bioavailability, simulation of PK, and drug absorption in various intestinal segments across species. This combined approach may facilitate a more comprehensive and accurate analysis of the absorption characteristics of active ingredients of Chinese medicine from in vitro and in vivo perspectives. 展开更多
关键词 Biopharmaceutical classification system BAICALEIN Intrinsic dissolution rate In situ intestinal perfusion Physiologically based pharmacokinetics absorption properties
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Improved Visible Transparency of SiO_2/ZnO:Al/CeO_2-TiO_2/SiO_2 Multilayer Films with High UV Absorption and Infrared Reflection Rate 被引量:1
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作者 倪佳苗 赵修建 +1 位作者 ZHAO Qingnan ZHENG Mindong 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS 2015年第5期941-946,共6页
New visible transparent, UV absorption, and high infrared reflection properties have been realized by depositing multilayer Si O2/Zn O: Al/Ce O2-Ti O2/Si O2 films onto glass substrates at low temperature by radio freq... New visible transparent, UV absorption, and high infrared reflection properties have been realized by depositing multilayer Si O2/Zn O: Al/Ce O2-Ti O2/Si O2 films onto glass substrates at low temperature by radio frequency magnetron sputtering. Optimum thickness of Si O2, Zn O: Al(ZAO) and Ce O2-Ti O2(CTO) films were designed with the aid of thin film design software. The degree of antireflection can be controlled by adjusting the thickness and refractive index. The outer Si O2 film can diminish the interference coloring and increase the transparency; the inner Si O2 film improves the adhesion of the coating on the glass substrate and prevents Ca2+, Na+ in the glass substrate from entering the ZAO film. The average transmittance in the visible light range increases by nearly 18%-20%, as compared to double layer ZAO/CTO films. And the films display high infrared reflection rate of above 75% in the wavelength range of 10-25 μm and good UV absorption(> 98%) properties. These systems are easy to produce on a large scale at low cost and exhibit high mechanical and chemical durability. The triple functional films with high UV absorption, antireflective and high infrared reflection rate will adapt to application in flat panel display and architectural coating glass, automotive glass, with diminishing light pollution as well as decreasing eye fatigue and increasing comfort. 展开更多
关键词 Si O2/Zn O:Al /Ce O2-Ti O2/Si O2 TRANSPARENCY high infrared reflection rate ultraviolet absorption optimization
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Experimental Studies on the Influence of HCO<sub>3</sub>- on Absorption and Desorption of CO<sub>2</sub>from Ammonia Solution 被引量:1
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作者 Shaojian Jiang Wei Zhong +2 位作者 Rui Peng Yong Jiang Jun Zhang 《Advances in Materials Physics and Chemistry》 2012年第4期240-243,共4页
With aqueous ammonia in the process of CO2 absorption and desorption to join sodium bicarbonate, the influence of HCO3- on CO2 absorption and desorption from ammonia solution was investigated through the experimental ... With aqueous ammonia in the process of CO2 absorption and desorption to join sodium bicarbonate, the influence of HCO3- on CO2 absorption and desorption from ammonia solution was investigated through the experimental analysis of the desorption quantity of CO2, desorption rate, CO2 loading and the absorption rate. The experimental results showed that, in experimental conditions, The desorption rate decreased gradually with increasing ammonia concentrations. The desorption rate increased 12%, 17%, 19% and 28.8% when 1 mol/L of ammonia solution is added in 0.1 mol/L, 0.3 mol/L, 0.5 mol/L and 1 mol/L of sodium bicarbonate. The higher concentration of ammonium bicarbonate solution which was added sodium bicarbonate,the more observably the effect of CO2 desorption was promoted. The absorption rate had dropped when absorption process added 0.3 mol/L sodium bicarbonate, the CO2 loading was a little change. 展开更多
关键词 Ammonia DESORPTION the DESORPTION rate CO2 absorption CO2 Loading
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Experimental Study of the Physical and Mechanical Behaviour of Mortar Formulations with Fine Sands of Recycled Glass
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作者 Apedjinou Dodji Kplolanyo Samah Essoavama Ouro-Djobo +2 位作者 Amey Kossi Bollanigni Kassegne Komlan Assogba Tiem Sonnou 《Open Journal of Civil Engineering》 2023年第2期252-262,共11页
This work is part of an experimental contribution approach to the study of the incorporation of glass sand from the grinding of recycled glass waste in cement mortars and its influence on the physical and mechanical b... This work is part of an experimental contribution approach to the study of the incorporation of glass sand from the grinding of recycled glass waste in cement mortars and its influence on the physical and mechanical behavior of semi-rich mortars without adjuvants. For this purpose, after a physical characterization of the sands, eight (08) formulations of mortars based on cement CEM II B/L 32.5R and fine sands (0/2) of glass at mass contents of 0%, 10%, 20%, 30%, 40%, 50%, 75% and 100% of the silty sand (0/2) were made respectively to three (03) types of fine glass sand (white, brown, green) with water dosages on cement (W/C) of 0.50, 0.45, 0.40. The results obtained show that the fine sands of recycled glass have a higher water absorption than the silty sand and the physical properties of the mortars prepared are affected by the increase in the glass content. The mechanical performances are obtained for the ratio W/C = 0.50 and the formulation of glass mortars for an optimal compressive strength superior to glass-free mortar requires a substitution of 10% for fine white glass sand, 20% for sand fine green glass and 75% for fine brown glass sand. The comparative study between these different compositions of fine glass sand mortars shows that the mechanical performances of fine brown glass sand are better than other glass sands but generally remain inferior to the control mortar based on natural silty sand. 展开更多
关键词 Glass Waste Glass Sand MORTAR Compression Strength Bending Strength absorption rate
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In-depth investigation on the factors affecting the performance of high oil-absorption resin by response surface method
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作者 Lei Ma Hongxia Lv +6 位作者 Haonan Yu Lingtong Kong Rongyue Zhang Xiaoyan Guo Haibo Jin Guangxiang He Xiaoyan Liu 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2021年第5期286-296,共11页
A series of high oil-absorption resins with low cross-linking degree were synthesized by suspension polymerization using stearyl methacrylate(SMA),2-Ethylhexyl methacrylate(EHMA),and styrene(St)as monomers.Response su... A series of high oil-absorption resins with low cross-linking degree were synthesized by suspension polymerization using stearyl methacrylate(SMA),2-Ethylhexyl methacrylate(EHMA),and styrene(St)as monomers.Response surface methodology(RSM)with central composite design(CCD)was also applied to determine the optimal parameters that are mainly known to affect their synthesis.Thus,the effects of the monomer mass ratio(EHMA:SMA),the rigid monomer(St)dosage,the porous agent(acetone)dosage,and their pairwise interaction on the resin's oil-absorption capacity were analyzed,highlighting PSES-R_(2) as the resin with the optimum performance.The pure oil-absorption rates of PSES-R_(2) for gasoline,diesel,and kerosene were 11.19 g·g^(-1),16.25 g·g^(-1),and 14.84 g·g^(-1),respectively,while the oil removal rates from oily wastewater were 98.82%,65.11%,and 99.63%,respectively. 展开更多
关键词 Oil-absorption RESIN Response surface method OIL removal rate Waste water absorption POLYMERIZATION
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Relationship between the incidence of non-hepatic hyperammonemia and the prognosis of patients in the intensive care unit
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作者 Zhi-Peng Yao Yue Li +1 位作者 Yang Liu Hong-Liang Wang 《World Journal of Gastroenterology》 SCIE CAS 2020年第45期7222-7231,共10页
BACKGROUND Ammonia is a normal constituent of body fluids and is found mainly through the formation of urea in the liver.Blood levels of ammonia must remain low as even slightly elevated concentrations(hyperammonemia)... BACKGROUND Ammonia is a normal constituent of body fluids and is found mainly through the formation of urea in the liver.Blood levels of ammonia must remain low as even slightly elevated concentrations(hyperammonemia)are toxic to the central nervous system.AIM To examine the relationship between the incidence of non-hepatic hyperammonemia(NHH)and the prognosis of patients who were admitted to the intensive care unit(ICU).METHODS This is a prospective,observational and single-center study.A total of 364 patients who were admitted to the ICU from November 2019 to February 2020 were initially enrolled.Changes in the levels of blood ammonia at the time of ICU admission and after ICU admission were continuously monitored.In addition,factors influencing the prognosis of NHH patients were analyzed.RESULTS A total of 204 patients who met the inclusion criteria were enrolled in this study,including 155 NHH patients and 44 severe-NHH patients.The incidence of NHH and severe-NHH was 75.98% and 21.57%,respectively.Patients with severe-NHH exhibited longer length of ICU stay and higher Acute Physiologic Assessment and Chronic Health Evaluation and Sequential Organ Failure Assessment scores compared to those with mild-NHH and non-NHH.Glasgow Coma Scale scores of patients with severe-NHH were than those of non-NHH patients.In addition,the mean and initial levels of ammonia in the blood might be helpful in predicting the prognosis of NHH.CONCLUSION High blood ammonia level is frequent among NHH patients admitted to the ICU,which is related to the clinical characteristics of patients.Furthermore,the level of blood ammonia may be helpful for prognosis prediction. 展开更多
关键词 Non-hepatic hyperammonemia Intestinal absorption Blood ammonia level Metabolism of amino acid Severe patients Intensive care unit
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Application of Exponential Distribution in Modeling of State Holding Time in HIV/AIDS Transition Dynamics
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作者 Nahashon Mwirigi 《Open Journal of Modelling and Simulation》 2024年第4期159-183,共25页
Markov modeling of HIV/AIDS progression was done under the assumption that the state holding time (waiting time) had a constant hazard. This paper discusses the properties of the hazard function of the Exponential dis... Markov modeling of HIV/AIDS progression was done under the assumption that the state holding time (waiting time) had a constant hazard. This paper discusses the properties of the hazard function of the Exponential distributions and its modifications namely;Parameter proportion hazard (PH) and Accelerated failure time models (AFT) and their effectiveness in modeling the state holding time in Markov modeling of HIV/AIDS progression with and without risk factors. Patients were categorized by gender and age with female gender being the baseline. Data simulated using R software was fitted to each model, and the model parameters were estimated. The estimated P and Z values were then used to test the null hypothesis that the state waiting time data followed an Exponential distribution. Model identification criteria;Akaike information criteria (AIC), Bayesian information criteria (BIC), log-likelihood (LL), and R2 were used to evaluate the performance of the models. For the Survival Regression model, P and Z values supported the non-rejection of the null hypothesis for mixed gender without interaction and supported the rejection of the same for mixed gender with interaction term and males aged 50 - 60 years. Both Parameters supported the non-rejection of the null hypothesis in the rest of the age groups. For Gender male with interaction both P and Z values supported rejection in all the age groups except the age group 20 - 30 years. For Cox Proportional hazard and AFT models, both P and Z values supported the non-rejection of the null hypothesis across all age groups. The P-values for the three models supported different decisions for and against the Null hypothesis with AFT and Cox values supporting similar decisions in most of the age groups. Among the models considered, the regression assumption provided a superior fit based on (AIC), (BIC), (LL), and R2 Model identification criteria. This was particularly evident in age and gender subgroups where the data exhibited non-proportional hazards and violated the assumptions required for the Cox Proportional Hazard model. Moreover, the simplicity of the regression model, along with its ability to capture essential state transitions without over fitting, made it a more appropriate choice. 展开更多
关键词 Markov Chain Markov Process Semi Markov Process Markov Decision Tree Stochastic Process Survival rate CD4+ Levels absorption rates AFT Model PH Model
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The Prognostic Value of Red Cell Distribution Width in Critically Ill Cerebral Infarction Patients:A Retrospective Cohort Study
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作者 Lingyan Zhao Linna Wu Gui-Ping Li 《Journal of Clinical and Nursing Research》 2024年第2期1-12,共12页
Objective:Red blood cell distribution width(RDW)has been utilized as a prognostic indicator for mortality risk assessment in cardiovascular and cerebrovascular patients.Nevertheless,the prognostic significance of RDW ... Objective:Red blood cell distribution width(RDW)has been utilized as a prognostic indicator for mortality risk assessment in cardiovascular and cerebrovascular patients.Nevertheless,the prognostic significance of RDW in critically ill patients with cerebral infarction is yet to be investigated.The objective of this study is to examine the association between RDW and the risk of all-cause mortality in cerebral infarction patients admitted to the intensive care unit(ICU).Method:A retrospective cohort study was conducted using the Medical Information Mart for Intensive Care IV 2.2(MIMIC-IV)intensive care dataset for data analysis.The main results were the all-cause mortality rates at 3 and 12 months of follow-up.Cumulative curves were plotted using the Kaplan-Meier method,and Cox proportional hazards analysis was used to examine the relationship between RDW and mortality rates in critically ill cerebral infarction patients.Results:The findings indicate that RDW serves as a significant prognostic factor for mortality risk in critically ill stroke patients,specifically at the 3 and 12-month follow-up periods.The observed correlation between increasing RDW levels and higher mortality rates among cerebral infarction patients further supports the potential utility of RDW as a predictive indicator.Conclusion:RDW emerges as an independent predictor of mortality risk during the 3 and 12-month follow-up periods for critically ill patients with cerebral infarction. 展开更多
关键词 Red blood cell distribution width Cerebral infarction Intensive care unit All-cause mortality rate MIMIC-IV database
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Measurement Analysis of Specific Absorption Rate in Human Body Exposed to a Base Station Antenna by Using Finite Difference Time Domain Techniques
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作者 Hla Myo Tun Khin Kyu Kyu Win +2 位作者 Zaw Min Naing Devasis Pradhan Prasanna Kumar Sahu 《Semiconductor Science and Information Devices》 2021年第2期17-26,共10页
The system analysis of specific absorption rate(SAR)in human body ex­posed to a base station antenna by using finite difference time domain tech­niques was presented in this research works.The objectives of ... The system analysis of specific absorption rate(SAR)in human body ex­posed to a base station antenna by using finite difference time domain tech­niques was presented in this research works.The objectives of this work are to evaluate the knowledge and awareness about SAR among human body and mobile base station.The paper investigates the electromagnetic wave absorption inside a human body.The human body has been identified us­ing dataset based on 2D object considering different electrical parameters.The SAR convinced inside the human body model exposed to a radiating base station antenna(BSA)has been considered for multiple numbers of carrier frequencies and input power of 20 W/carrier at GSM 900 band.The distance(R)of human body from BSA is varied in the range of 0.1 m to 5.0 m.For the number of carrier frequency equal to one and R=0.1 m,the concentrated value of whole-body average SAR obtained by FDTD technique is found to be 0.68 W/kg which decreases either with increase of R or decrease of number of carrier frequencies.Safety distance for general public is found to be 1.5 m for number of carrier frequencies equal to one.The performance accuracy of this analysis meets the high level condition by comparing with the relevant system development in recent time. 展开更多
关键词 Specific absorption rate(SAR) Electromagnetic wave Mobile basic station Public health safety RF waves
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Energy Absorption of Pultruded Glass-Graphite/Epoxy Hybrid Composites under High Strain-Rate Induced Transverse Tension
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作者 Damian Stoddard Suman Babu Ukyam +1 位作者 R. Mantena Prabhakar Arunachalam Rajendran 《Open Journal of Composite Materials》 2018年第2期43-53,共11页
This paper focuses on the dynamic tensile response of glass-graphite/epoxy composites illustrating improvement in energy absorption through hybridization. The dynamic response and energy absorption characteristics of ... This paper focuses on the dynamic tensile response of glass-graphite/epoxy composites illustrating improvement in energy absorption through hybridization. The dynamic response and energy absorption characteristics of pultruded hybrid combinations of glass and graphite fibers in an epoxy matrix subjected to induced transverse tension at high strain-rate in a modified Split Hopkinson Pressure Bar (SHPB) apparatus, are presented. Transverse tensile strength was determined by diametral compression of disc samples (Brazilian indirect tensile test method). Diametral crack initiation and strain to failure were monitored with a Shimadzu HPV-2 high-speed video camera at a recording speed of 500,000 fps and Digital Image Correlation (DIC). Adequate measures were taken to ensure that initiation of specimen failure occurred at the exact center of the disc specimen, and propagated through the diameter along the compressive loading axis, for the induced transverse tension tests to be valid. A study of the strength and specific energy absorption demonstrates the benefits of hybridization. Under induced transverse tensile loading condition, the pure glass/epoxy (GL60) exhibited higher strength than pure graphite/epoxy (GR60). Pure graphite/epoxy (GR60) has higher specific energy absorption capacity than pure glass/epoxy (GL60) in transverse tension. Among all hybrids, GR30 has the highest specific energy absorption under transverse tension. Overall, hybrid GL48, with 48% low-cost glass fibers in the inner core and 12% high-cost graphite fibers in outer shell, was found to exhibit better performance under induced transverse tension at high strain-rates, showing the benefits of hybridization. 展开更多
关键词 Pultruded Composites HYBRIDS HIGH STRAIN-rate SHPB Dynamic Energy absorption BRAZILIAN Disc Indirect Tensile Test
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Calculation of Electromagnetic Field and SAR Dis- tributions of Two Antenna Structures for Bone Tu- mors Microwave Hyperthermia 被引量:1
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作者 席晓莉 汪文秉 王丽黎 《Journal of Nanjing Medical University》 2003年第3期143-148,共6页
Objective: To investigate the electromagnetic field and specific absorptionrate (SAR) distribution of different structure applicators with different depths for treating bonetumors using microwave hyperthermia. Methods... Objective: To investigate the electromagnetic field and specific absorptionrate (SAR) distribution of different structure applicators with different depths for treating bonetumors using microwave hyperthermia. Methods: The finite element method (FEM) was used to calculate,electromagnetic field and SAR distribution. Two different structure applicators were simulated. Theone is simple coaxial antenna, which has been successfully used in clinic treating bone tumors inTangdu hospital of the Forth Military Medical University several years. It was formed by a coaxialcable peeled off the out copper at end. The other applicator was coaxial- slot antenna, which waswidely used in microwave hyperthermia. The applicator inserted into the cylindrical bone withdifferent depths, and worked at the frequency of 2 450 MHz. Results: The electric field and SARgenerated by the simple coaxial applicator were mainly concentrated out the tissues, and were notuniform in the tissues, while the coaxial- slot applicator well transmits the electric field and SARinto the tissues, and can easily treat different position by adjusting the slat position.Conclusion: The results calculated by EFM, were well accordant with the experimental and clinicalresulls, and will be important for improving the clinical effects of microwave hyperthermia. 展开更多
关键词 bone tumors microwave hyperthermia finite element method electromagnetic field specific absorption rate
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Wide-band underwater acoustic absorption based on locally resonant unit and interpenetrating network structure 被引量:5
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作者 姜恒 王育人 +4 位作者 张密林 胡燕萍 蓝鼎 吴群力 逯还通 《Chinese Physics B》 SCIE EI CAS CSCD 2010年第2期367-372,共6页
The interpenetrating network structure provides an interesting avenue to novel materials. Locally resonant phononic crystal (LRPC) exhibits excellent sound attenuation performance based on the periodical arrangement... The interpenetrating network structure provides an interesting avenue to novel materials. Locally resonant phononic crystal (LRPC) exhibits excellent sound attenuation performance based on the periodical arrangement of sound wave scatters. Combining the LRPC concept and interpenetrating network glassy structure, this paper has developed a new material which can achieve a wide band underwater strong acoustic absorption. Underwater absorption coefficients of different samples were measured by the pulse tube. Measurement results show that the new material possesses excellent underwater acoustic effects in a wide frequency range.Moreover, in order to investigate impacts of locally resonant units,some defects are introduced into the sample. The experimental result and the theoretical calculation both show that locally resonant units being connected to a network structure play an important role in achieving a wide band strong acoustic absorption. 展开更多
关键词 underwater acoustic absorption wide frequency locally resonant unit interpenetrating networks
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