目的 探讨紫癜性肾炎(HSPN)患儿PLT、血小板压积(PCT)等血小板参数与肾脏病理分级及肾功能的关系。方法 回顾性分析2022年1月至2023年3月河南中医药大学第一附属医院收治的46例过敏性紫癜(HSP)和89例HSPN患儿的临床资料,比较两组患儿血...目的 探讨紫癜性肾炎(HSPN)患儿PLT、血小板压积(PCT)等血小板参数与肾脏病理分级及肾功能的关系。方法 回顾性分析2022年1月至2023年3月河南中医药大学第一附属医院收治的46例过敏性紫癜(HSP)和89例HSPN患儿的临床资料,比较两组患儿血小板参数、凝血功能、肾功能水平。HSPN患儿根据肾脏病理结果分为Ⅱ型28例、Ⅲa型32例、Ⅲb及以上29例,比较不同肾脏病理分型HSPN患儿血小板参数、凝血功能、肾功能水平、24 h尿蛋白含量(24 h UP);采用Pearson相关分析血小板参数与凝血功能、肾功能水平的关系。采用ROC曲线评价血小板参数对HSPN患儿肾功能障碍的诊断效能。结果 HSPN组PLT、PCT、尿素氮(BUN)、血肌酐(Scr)、TT水平均高于HSP组,APTT水平低于HSP组(均P<0.05)。随着肾脏病理分型的升高,PLT、PCT、BUN、24 h UP水平逐渐上升,3组间差异有统计学意义(均P<0.05)。Pearson相关分析显示,HSPN患儿PLT、PCT水平与BUN、Scr、24 h UP均呈正相关(均P<0.05)。ROC曲线分析表明,PLT、PCT两者联合诊断HSPN患儿发生肾功能障碍的AUC为0.880,高于单一指标诊断(均P<0.05),灵敏度为0.727,特异度为0.978。结论 不同肾脏病理分型HSPN患儿PLT、PCT水平存在显著差异,与肾功能指标呈显著正相关。检测HSPN患儿PLT、PCT水平有助于评估其肾脏病理分型和肾功能障碍发生情况。展开更多
Rock burst is a severe disaster in mining and underground engineering,and it is important to predict the rock burst risk for minimizing the loss during the constructing process.The rock burst proneness was connected w...Rock burst is a severe disaster in mining and underground engineering,and it is important to predict the rock burst risk for minimizing the loss during the constructing process.The rock burst proneness was connected with the acoustic emission(AE) parameter in this work,which contributes to predicting the rock burst risk using AE technique.Primarily,a rock burst proneness index is proposed,and it just depends on the heterogeneous degree of rock material.Then,the quantificational formula between the value of rock burst proneness index and the accumulative AE counts in rock sample under uniaxial compression with axial strain increases is developed.Finally,three kinds of rock samples,i.e.,granite,limestone and sandstone are tested about variation of the accumulative AE counts under uniaxial compression,and the test data are fitted well with the theoretic formula.展开更多
文摘目的 探讨紫癜性肾炎(HSPN)患儿PLT、血小板压积(PCT)等血小板参数与肾脏病理分级及肾功能的关系。方法 回顾性分析2022年1月至2023年3月河南中医药大学第一附属医院收治的46例过敏性紫癜(HSP)和89例HSPN患儿的临床资料,比较两组患儿血小板参数、凝血功能、肾功能水平。HSPN患儿根据肾脏病理结果分为Ⅱ型28例、Ⅲa型32例、Ⅲb及以上29例,比较不同肾脏病理分型HSPN患儿血小板参数、凝血功能、肾功能水平、24 h尿蛋白含量(24 h UP);采用Pearson相关分析血小板参数与凝血功能、肾功能水平的关系。采用ROC曲线评价血小板参数对HSPN患儿肾功能障碍的诊断效能。结果 HSPN组PLT、PCT、尿素氮(BUN)、血肌酐(Scr)、TT水平均高于HSP组,APTT水平低于HSP组(均P<0.05)。随着肾脏病理分型的升高,PLT、PCT、BUN、24 h UP水平逐渐上升,3组间差异有统计学意义(均P<0.05)。Pearson相关分析显示,HSPN患儿PLT、PCT水平与BUN、Scr、24 h UP均呈正相关(均P<0.05)。ROC曲线分析表明,PLT、PCT两者联合诊断HSPN患儿发生肾功能障碍的AUC为0.880,高于单一指标诊断(均P<0.05),灵敏度为0.727,特异度为0.978。结论 不同肾脏病理分型HSPN患儿PLT、PCT水平存在显著差异,与肾功能指标呈显著正相关。检测HSPN患儿PLT、PCT水平有助于评估其肾脏病理分型和肾功能障碍发生情况。
基金Project(2010CB226804)supported by the National Basic Research Program(973 Program)of ChinaProject(11202108)supported by the National Natural Science Foundation of ChinaProject(BK20130189)supported by the Natural Science Foundation of Jiangsu Province,China
文摘Rock burst is a severe disaster in mining and underground engineering,and it is important to predict the rock burst risk for minimizing the loss during the constructing process.The rock burst proneness was connected with the acoustic emission(AE) parameter in this work,which contributes to predicting the rock burst risk using AE technique.Primarily,a rock burst proneness index is proposed,and it just depends on the heterogeneous degree of rock material.Then,the quantificational formula between the value of rock burst proneness index and the accumulative AE counts in rock sample under uniaxial compression with axial strain increases is developed.Finally,three kinds of rock samples,i.e.,granite,limestone and sandstone are tested about variation of the accumulative AE counts under uniaxial compression,and the test data are fitted well with the theoretic formula.