AIM:To assess the antacid effects of the tonic Chinese herbal prescriptions,Si-Jun-Zi-Tang(SJZT) and Shen-Ling-Bai-Zhu-San(SLBZS).METHODS:Decoctions of the tonic Chinese herbal prescriptions,SJZT and SLBZS,were prepar...AIM:To assess the antacid effects of the tonic Chinese herbal prescriptions,Si-Jun-Zi-Tang(SJZT) and Shen-Ling-Bai-Zhu-San(SLBZS).METHODS:Decoctions of the tonic Chinese herbal prescriptions,SJZT and SLBZS,were prepared according to Chinese original documents.The pH of the prescription decoctions and their neutralizing effects on artif icial gastric acids were determined and compared with water and the active controls,sodium bicarbonate and colloidal aluminum phosphate.A modified model of Vatier's artificial stomach was used to determine the duration of consistent neutralization effect on artificial gastric acids.The neutralization capacity in vitro was determined with the titration method of Fordtran's model.RESULTS:The results showed that both SJZT and SLBZS have antacid effects in vitro.Compared with the water group,SJZT and SLBZS were found to possess signif icant gastric acid neutralizing effects.The duration for consistent neutralization of SLBZS was signif icantly longer than that of water.Also,SLBZS and SJZT exhibited signif icant antacid capacities compared to water.CONCLUSION:SJZT and SLBZS were consistently active in the artificial stomach model and are suggested to have antacid effects similar to the active control drugs.展开更多
煤矸石自身酸碱性是判断煤矸石堆体能否发生酸性矿山排水的重要依据,为了探究阜新市海州立井矿煤矸石产酸潜能,开展了酸碱计算法试验(ABA)、净产酸量试验(NAG)、酸/碱中和能力试验(ANC),结果表明:煤矸石的NP/AP<1,NAG p H<4.5,煤...煤矸石自身酸碱性是判断煤矸石堆体能否发生酸性矿山排水的重要依据,为了探究阜新市海州立井矿煤矸石产酸潜能,开展了酸碱计算法试验(ABA)、净产酸量试验(NAG)、酸/碱中和能力试验(ANC),结果表明:煤矸石的NP/AP<1,NAG p H<4.5,煤矸石具有低产酸潜能,对碱具有一定的中和能力;ANC试验结果显示煤矸石自然p H值呈弱酸性,1 kg煤矸石约需要0.090 mol碱使之中和,ANC试验结果体现的是稳定状态下全部废石的缓冲能力,净产酸量小于另外两种方法;海州立井矿主要产出低硫煤,煤矸石中硫含量不高,碳酸盐硅酸盐等碱性矿物能够中和一部分酸,加之雨水淋滤风化等作用,发生酸性矿山排水的危险性较小。展开更多
基金Supported by A Research Grant from Yen Kun Yin Cultural and Educational Foundation, Taipei, Taiwan, China
文摘AIM:To assess the antacid effects of the tonic Chinese herbal prescriptions,Si-Jun-Zi-Tang(SJZT) and Shen-Ling-Bai-Zhu-San(SLBZS).METHODS:Decoctions of the tonic Chinese herbal prescriptions,SJZT and SLBZS,were prepared according to Chinese original documents.The pH of the prescription decoctions and their neutralizing effects on artif icial gastric acids were determined and compared with water and the active controls,sodium bicarbonate and colloidal aluminum phosphate.A modified model of Vatier's artificial stomach was used to determine the duration of consistent neutralization effect on artificial gastric acids.The neutralization capacity in vitro was determined with the titration method of Fordtran's model.RESULTS:The results showed that both SJZT and SLBZS have antacid effects in vitro.Compared with the water group,SJZT and SLBZS were found to possess signif icant gastric acid neutralizing effects.The duration for consistent neutralization of SLBZS was signif icantly longer than that of water.Also,SLBZS and SJZT exhibited signif icant antacid capacities compared to water.CONCLUSION:SJZT and SLBZS were consistently active in the artificial stomach model and are suggested to have antacid effects similar to the active control drugs.
