以4,4'-二氨基二苯砜(DDS)为固化剂,用端环氧基丁腈橡胶(ETBN)增韧4,4'-二氨基二苯甲烷环氧树脂(TGDDM),通过差示扫描量热法和傅里叶变换红外光谱法分析了ETBN增韧TGDDM的固化行为,考察了ETBN含量对增韧TGDDM力学性能和吸水率...以4,4'-二氨基二苯砜(DDS)为固化剂,用端环氧基丁腈橡胶(ETBN)增韧4,4'-二氨基二苯甲烷环氧树脂(TGDDM),通过差示扫描量热法和傅里叶变换红外光谱法分析了ETBN增韧TGDDM的固化行为,考察了ETBN含量对增韧TGDDM力学性能和吸水率的影响,表征了ETBN增韧TGDDM的微观形貌。结果表明,随着ETBN含量的增加,增韧TGDDM的固化反应放热量逐渐下降,固化放热峰温度则逐渐升高,ETBN与TGDDM在固化过程中反应完全;随着ETBN含量的增加,增韧TGDDM的弯曲强度和弯曲弹性模量都逐渐下降,冲击强度和断裂韧性则先升高后降低,当ETBN质量分数为6.7%时达到最大值,分别为15.9 k J/m2和0.74 MPa·m1/2;未增韧TGDDM表面平滑,裂纹几乎呈直线状,表现为脆性断裂;加入的ETBN均匀分散在TGDDM中,随着ETBN含量的增加,ETBN粒子尺寸增大;ETBN增韧TGDDM具有良好的耐水性。展开更多
In this paper the measurement of crystallinity(C)ofacrylic copolymer(PAC),by Swelling Differential Scan-ning Calorimetry(SDSC)is discussed.Common DSC isonly used for measuring the crystallinity of polymers withmelting...In this paper the measurement of crystallinity(C)ofacrylic copolymer(PAC),by Swelling Differential Scan-ning Calorimetry(SDSC)is discussed.Common DSC isonly used for measuring the crystallinity of polymers withmelting point,(T_m),below their decomposition temper-ature,(T_d).As temperature rises,polymers with swell-ing agent added become swollen and dissolved,goingthrough whole process of breaking solid structures.Thus,SDSC makes it possible to measure the crystallini-ty of polymers even with T_d below T_m.But the C mea-sured by WAXD and the total endothermal melting(swelling)heat in SDSC thermograms,(△H_l),are notlinearly correlated.It has been found that,instead of the△H_l,△H_l’obtained from the △H_l by subtracting the en-dothermal heat,△H_l,and the C measured by WAXDare linearly correlated.On the basis of this linear rela-tion,the unknown C of another PAC sample is measuredby SDSC.The result is in good accordance with thatmeasured by WAXD.展开更多
Objectives To evaluate the anti- ischemic effect of ISDN on the patients with coronary heart disease . The change in the size of the defect area as percentage of the entire myocardium as determined by the unfolded sur...Objectives To evaluate the anti- ischemic effect of ISDN on the patients with coronary heart disease . The change in the size of the defect area as percentage of the entire myocardium as determined by the unfolded surface mapping between the baseline and after ISDN infusion reflects the anti-ischemic effect of ISDN. Methods and Results 99m Tc-MIBI myocardial perfusion SPECT images were acquired, and reconstruction of the bull's eye map and unfolded surface mapping were performed according to the dates of tomography images. In the group (99mTc-MIBI was injected at 30 minutes after the start of ISDN iv drip) : at the 65% threshold value, the percentage of the defect area size in the whole ventricle was 33.01 ± 5.35% at baseline, (28.9 ±5.23)% after ISDN was infused (P < 0.05); at the 55% threshold value, the percentage of the defect area size in the whole ventricle was (22.06±5.58)% at baseline, (19.60±4.07)% after ISDN was infused (P < 0.05); the sum of defect blood ST segments is 60 at baseline, 51 after ISDN was infused. In the group (99mTc-MIBI was injected at 60 minutes after the start of ISDN iv drip): at the 65% threshold value, the percentage of the defect area size in the whole ventricle was (29.20±5.08)% at baseline, (20.81±4.16)% after ISDN was infused (P < 0.001); at the 55% threshold value, the percentage of the defect area size in the whole ventricle was (21.2 ± 5.49)% at baseline, (17.52±5.59)% after ISDN was infused (P < 0.001); the sum of defect blood ST segments is 58 at baseline, 47 after ISDN was infused. In the group (99mTc-MIBI was injected at 150 minutes after the start of ISDN iv drip) : at the 65% threshold value, the percentage of the defect area size in the whole ventricle was (32.87 ±6.46)% at baseline, (20.81±4.16)% after ISDN was infused (P < 0.001); at the 55% threshold value, the percentage of the defect area size in the whole ventricle was (18.42± 5.17)% at baseline, (14.18±3.61)% after ISDN was infused (P< 0.001); the sum of defect blood ST segments was 64 at baseline, 41 after ISDN was infused. Conclusions The unfolded surface mapping of 99mTc- MIBI myocardial perfusion image can be used as a method of quantitatively evaluating the anti-ischemic effect of drugs and ISDN iv drip can improve the blood flow in myocardium (myocardium perfusion).展开更多
The three-component reaction of thiazole （benzothiazole）, dialkyl but-2-ynedioate, and isatinylidene malononi- triles in toluene at 110-120 ℃ in a sealed tube afforded a mixture of cis/trans-isomers of functionaliz...The three-component reaction of thiazole （benzothiazole）, dialkyl but-2-ynedioate, and isatinylidene malononi- triles in toluene at 110-120 ℃ in a sealed tube afforded a mixture of cis/trans-isomers of functionalized di- astereoisomeric spiro[indoline-3,7＇-thiazolo[3,2-a]pyridines] and spiro[benzo[4,5]thiazolo[3,2-a]pyridine-3,3＇-in- dolines] in good yields. Both cis-isomers and trans-isomers were successfully separated out and fully characterized with spectroscopy and single crystal determination. Under similar conditions, the three-component reaction con- taining 2-（1,3-dioxo-lH-inden-2（3H）-ylidene）malononitrile resulted in spiro[indene-2,7＇-thiazolo[3,2-a]pyridine] derivatives.展开更多
文摘以4,4'-二氨基二苯砜(DDS)为固化剂,用端环氧基丁腈橡胶(ETBN)增韧4,4'-二氨基二苯甲烷环氧树脂(TGDDM),通过差示扫描量热法和傅里叶变换红外光谱法分析了ETBN增韧TGDDM的固化行为,考察了ETBN含量对增韧TGDDM力学性能和吸水率的影响,表征了ETBN增韧TGDDM的微观形貌。结果表明,随着ETBN含量的增加,增韧TGDDM的固化反应放热量逐渐下降,固化放热峰温度则逐渐升高,ETBN与TGDDM在固化过程中反应完全;随着ETBN含量的增加,增韧TGDDM的弯曲强度和弯曲弹性模量都逐渐下降,冲击强度和断裂韧性则先升高后降低,当ETBN质量分数为6.7%时达到最大值,分别为15.9 k J/m2和0.74 MPa·m1/2;未增韧TGDDM表面平滑,裂纹几乎呈直线状,表现为脆性断裂;加入的ETBN均匀分散在TGDDM中,随着ETBN含量的增加,ETBN粒子尺寸增大;ETBN增韧TGDDM具有良好的耐水性。
文摘以交联聚丙烯酸钠(CPNa AA)为吸水材料,通过动态硫化法制备了基于丙烯腈-丁二烯-苯乙烯共聚物(ABS)/丁腈橡胶(NBR)/氯化聚乙烯(CM)热塑性硫化胶(TPV)的吸水膨胀橡胶(WSR),考察了CPNa AA用量对WSR物理机械性能和吸水性能的影响,研究了WSR的微观形貌。结果表明,在实验范围内,ABS/NBR/CM/CPNa AA WSR的应力-应变行为均表现出"软而韧"的弹性体特征,随着CPNa AA用量的增加,WSR的拉伸强度、扯断伸长率、永久变形和撕裂强度均呈下降趋势,邵尔A硬度略有提高,WSR的吸水率、吸水速率及脱水失重率提高,当CPNa AA用量为70份时,室温下95 h WSR即达到吸水平衡状态,此时吸水率为369.8%;与第1次的最大吸水率相比,第2次及第3次的最大吸水率仅有小幅降低,但第2次及第3次的初始吸水速率远大于第1次的初始吸水速率,脱水失重率明显降低;CPNa AA在TPV中分散均匀,未出现团聚现象,但表面结构松散,与TPV之间的界面作用较弱;WSR吸水干燥后表面出现明显的缝隙和孔洞。
文摘In this paper the measurement of crystallinity(C)ofacrylic copolymer(PAC),by Swelling Differential Scan-ning Calorimetry(SDSC)is discussed.Common DSC isonly used for measuring the crystallinity of polymers withmelting point,(T_m),below their decomposition temper-ature,(T_d).As temperature rises,polymers with swell-ing agent added become swollen and dissolved,goingthrough whole process of breaking solid structures.Thus,SDSC makes it possible to measure the crystallini-ty of polymers even with T_d below T_m.But the C mea-sured by WAXD and the total endothermal melting(swelling)heat in SDSC thermograms,(△H_l),are notlinearly correlated.It has been found that,instead of the△H_l,△H_l’obtained from the △H_l by subtracting the en-dothermal heat,△H_l,and the C measured by WAXDare linearly correlated.On the basis of this linear rela-tion,the unknown C of another PAC sample is measuredby SDSC.The result is in good accordance with thatmeasured by WAXD.
文摘Objectives To evaluate the anti- ischemic effect of ISDN on the patients with coronary heart disease . The change in the size of the defect area as percentage of the entire myocardium as determined by the unfolded surface mapping between the baseline and after ISDN infusion reflects the anti-ischemic effect of ISDN. Methods and Results 99m Tc-MIBI myocardial perfusion SPECT images were acquired, and reconstruction of the bull's eye map and unfolded surface mapping were performed according to the dates of tomography images. In the group (99mTc-MIBI was injected at 30 minutes after the start of ISDN iv drip) : at the 65% threshold value, the percentage of the defect area size in the whole ventricle was 33.01 ± 5.35% at baseline, (28.9 ±5.23)% after ISDN was infused (P < 0.05); at the 55% threshold value, the percentage of the defect area size in the whole ventricle was (22.06±5.58)% at baseline, (19.60±4.07)% after ISDN was infused (P < 0.05); the sum of defect blood ST segments is 60 at baseline, 51 after ISDN was infused. In the group (99mTc-MIBI was injected at 60 minutes after the start of ISDN iv drip): at the 65% threshold value, the percentage of the defect area size in the whole ventricle was (29.20±5.08)% at baseline, (20.81±4.16)% after ISDN was infused (P < 0.001); at the 55% threshold value, the percentage of the defect area size in the whole ventricle was (21.2 ± 5.49)% at baseline, (17.52±5.59)% after ISDN was infused (P < 0.001); the sum of defect blood ST segments is 58 at baseline, 47 after ISDN was infused. In the group (99mTc-MIBI was injected at 150 minutes after the start of ISDN iv drip) : at the 65% threshold value, the percentage of the defect area size in the whole ventricle was (32.87 ±6.46)% at baseline, (20.81±4.16)% after ISDN was infused (P < 0.001); at the 55% threshold value, the percentage of the defect area size in the whole ventricle was (18.42± 5.17)% at baseline, (14.18±3.61)% after ISDN was infused (P< 0.001); the sum of defect blood ST segments was 64 at baseline, 41 after ISDN was infused. Conclusions The unfolded surface mapping of 99mTc- MIBI myocardial perfusion image can be used as a method of quantitatively evaluating the anti-ischemic effect of drugs and ISDN iv drip can improve the blood flow in myocardium (myocardium perfusion).
基金This work was financially supported by the National Natural Science Foundation of China （No. 21172189） and the Priority Academic Program Development of Jiangsu Higher Education Institutions. We also wanted to give sincerely thanks to the Analysis Center of Yangzhou University for providing all necessary in- struments for characterization of structures.
文摘The three-component reaction of thiazole （benzothiazole）, dialkyl but-2-ynedioate, and isatinylidene malononi- triles in toluene at 110-120 ℃ in a sealed tube afforded a mixture of cis/trans-isomers of functionalized di- astereoisomeric spiro[indoline-3,7＇-thiazolo[3,2-a]pyridines] and spiro[benzo[4,5]thiazolo[3,2-a]pyridine-3,3＇-in- dolines] in good yields. Both cis-isomers and trans-isomers were successfully separated out and fully characterized with spectroscopy and single crystal determination. Under similar conditions, the three-component reaction con- taining 2-（1,3-dioxo-lH-inden-2（3H）-ylidene）malononitrile resulted in spiro[indene-2,7＇-thiazolo[3,2-a]pyridine] derivatives.
