A new simple method in which arbitrary transfer function matrix is realized withactive multiple port network instead of computer simulating is proposed. The active multipleport network is carried on through state feed...A new simple method in which arbitrary transfer function matrix is realized withactive multiple port network instead of computer simulating is proposed. The active multipleport network is carried on through state feedback and state cross output for RC ladder network.The main process is to determine coefficients of each adder. Finally, an example is given forillustration.展开更多
Presents analytic criteria for the local activity theory in two-port cellularneural network (CNN) cells with four local state variables, and gives the application to a smoothedChua's circuit (SCC) CNN with two-por...Presents analytic criteria for the local activity theory in two-port cellularneural network (CNN) cells with four local state variables, and gives the application to a smoothedChua's circuit (SCC) CNN with two-port and I 5 S 15 arrays. The bifurcation diagrams of the SCC CNNshow that they are completely the same as those of an SCC CNN with one-port calculated earlier;which do not exist locally passive domain. The evolution of the patterns of the state variables ofthe SCC CNN is stimulated. Oscillatory patterns, chaotic patterns, or divergent patterns may emergeif the selected cell parameters are located in the locally active unstable domains but nearby theedge of chaos domain.展开更多
The study examined the impacts of urbanization-related activities on soil quality in Port Harcourt Metropolis-Rivers state,Nigeria.Experimental and survey research designs were implored in the study utilizing GIS and ...The study examined the impacts of urbanization-related activities on soil quality in Port Harcourt Metropolis-Rivers state,Nigeria.Experimental and survey research designs were implored in the study utilizing GIS and spatial analysis approaches.Both primary and secondary sources of data were used.The primary data were generated through laboratory analysis of soil samples from 15 randomly selected sites within the metropolis;and 800 valid copies of socio-economic questionnaire administered to 800 respondents.Also,public hospitals were visited to ascertain the commonest soil borne diseases in the area.Four research questions,four specific objectives and two hypotheses guided the study.The hypotheses were tested with one sample t-test and one sample chi square using SPSS.Standard scientific and laboratory procedures were followed in the collection and analysis of soil samples.Findings of the study include:urbanization-related activities(e.g.waste dumpsites,mechanic workshops,abattoirs,etc.)cause significant changes on soil quality in the area;and this result to the emergence of soil borne diseases(e.g.Vascular witts,Ascaris lumbricoids,Trichuris trichiura,Strongloids stereoralis)which affects residents’wellbeing.However,there is significant difference in the perceived socio-economic effects of the diseases across the area.Specifically,laboratory results for soil analysis show that(mean values):pH 7.22,temperature 25.62℃,PO_(4)0.342 mg/kg,Pb 120.62 mg/kg,K 66.81 mg/kg,NO_(3)mg/kg.The study recommended for enforcement of physical planning and development control laws;regular evaluation of the quality of the soil,and restriction on the location of mechanic workshops and waste dumpsites around the metropolis.展开更多
The Port Island Formation(PIF), a typical Cretaceous red bed in Hong Kong, is dominated by non-fossiliferous, reddish clastic rocks, making it difficult to determine the sedimentary age of PIF precisely. Previous stud...The Port Island Formation(PIF), a typical Cretaceous red bed in Hong Kong, is dominated by non-fossiliferous, reddish clastic rocks, making it difficult to determine the sedimentary age of PIF precisely. Previous studies assigned the PIF to Late Cretaceous provisionally only on the basis of its stratigraphic sequence and lithology. This study identified a tuffite interlayer in the PIF and a zircon UPb age of 128.2±2.7 Ma by LA-ICP-MS method was obtained. It’s the first time to date the depositional age of the PIF with a reliable chronological constraint. With the support of stratigraphic evidence, we concluded that the geological age of PIF should be Early Cretaceous rather than Late Cretaceous. Based on the volcanic history of Hong Kong and Southeast China and the distribution of the PIF in Mirs Bay, it is believed that there was no volcanic activity in Hong Kong in ca. 128 Ma. The tuffite interlayer discovered in PIF was formed by the deposition of volcanic ash, which might originate from remote region outside Hong Kong, in an aquatic environment on Port Island. The identification of the tuffite interlayer, as the response to a volcanic event, has great significance not only to the studies of establishment and regional correlation of the strata system and the geological evolution in Hong Kong,but also to the study of volcanic activities in Southeast China.展开更多
The monofunctional substitution reactions between trans-[PtCl（H2O）（NH3）（pip）]＋,trans-[Pt（H2O）2（NH3）（pip）]2＋,trans-[PtCl（H2O）（pip）2]＋,trans-[Pt（H2O）2（pip）2]2＋ （pip = piperidine） and adenine/gu...The monofunctional substitution reactions between trans-[PtCl（H2O）（NH3）（pip）]＋,trans-[Pt（H2O）2（NH3）（pip）]2＋,trans-[PtCl（H2O）（pip）2]＋,trans-[Pt（H2O）2（pip）2]2＋ （pip = piperidine） and adenine/guanine nucleotides are explored by using B3LYP hybrid functional and IEF-PCM salvation models. For the trans-[Pt（H2O）2（NH3）（pip）]2＋ and trans-[PtCl（H2O）（NH3）（pip）]＋ complexes,the computed barrier heights in aqueous solution are 13.5/13.5 and 11.6/11.6 kcal/mol from trans-Pt-chloroaqua complex to trans/cis-monoadduct for adenine and guanine,and the corresponding values are 20.7/20.7 and 18.8/18.8 kcal/mol from trans-Pt-diaqua complex to trans/cis-monoadduct for adenine and guanine,respectively. For trans-[PtCl（H2O）（pip）2]＋ and trans-[Pt（H2O）2（pip）2]2＋,the corresponding values are 21.5/21.3 and 19.4/19.4 kcal/mol,and 26.0/26.0 and 20.7/20.8 kal/mol for adenine and guanine,respectively. Our calculations demonstrate that the barrier heights of chloroaqua are lower than the corresponding values of diaqua for adenine and guanine. In addition,the free energies of activation for guanine in aqueous solution are all smaller than that for adenine,which predicts a preference of 1.9 kcal/mol when trans-[PtCl（H2O）（NH3）（pip）]＋ and trans-[Pt（H2O）2（NH3）（pip）]2＋ are the active agents and ～1.9 and ～ 5.3 kcal/mol when trans-[PtCl（H2O）（pip）2]＋ and trans-[Pt（H2O）2（pip）2]2＋ are the active agents,respectively. For the reaction of trans-Pt-chloroaqua （or diaqua） to cis-monoadduct,we obtain the same transition-state structure as from the reaction of trans-Pt-chloroaqua （or diaqua） to trans-monoadduct,which seems that the trans-Pt-chloroaqua （or diaqua） complex can generate trans-or cis-monoadduct via the same transition-state.展开更多
作为一种适应高比例分布式新能源接入的新型配电网架构,蜂巢状有源配电网利用多端口能量枢纽(multi-port energy hub,MEH)可实现多微电网/配网单元间功率的互联互济,如MEH中包含储能设备,可以进一步提升新能源利用率和电网可靠性。文中...作为一种适应高比例分布式新能源接入的新型配电网架构,蜂巢状有源配电网利用多端口能量枢纽(multi-port energy hub,MEH)可实现多微电网/配网单元间功率的互联互济,如MEH中包含储能设备,可以进一步提升新能源利用率和电网可靠性。文中提出一种含储能的MEH及其分层协调控制策略。上层控制根据储能系统的荷电状态和配电网运行状态协调控制储能变流器与各并网端口变流器之间的功率分配,使得MEH在平抑新能源波动、配网故障恢复等运行模式下均能够对内部储能系统进行能量管理。下层控制通过将储能变流器有功功率的微分值反馈至储能系统控制环路进行补偿,提高储能变流器输入/输出有功功率响应速度。文中设计了MEH控制系统关键参数,利用MATLAB/Simulink对MEH在配电系统中的应用进行仿真。不同工况下的仿真对比验证了所提分层协调控制策略的有效性,证明该策略能够延长储能系统工作时间,提高储能系统有功功率变化率,减小直流母线的电压波动。展开更多
In this study,37 derivatives of phorbol esters were synthesized and their anti-HIV-1 activities evaluated,building upon our previous synthesis of 51 phorbol derivatives.12-Para-electron-acceptor-trans-cinnamoyl-13-dec...In this study,37 derivatives of phorbol esters were synthesized and their anti-HIV-1 activities evaluated,building upon our previous synthesis of 51 phorbol derivatives.12-Para-electron-acceptor-trans-cinnamoyl-13-decanoyl phorbol derivatives stood out,demonstrating remarkable anti-HIV-1 activities and inhibitory effects on syncytia formation.These derivatives exhibited a higher safety index compared with the positive control drug.Among them,12-(trans-4-fluorocinnamoyl)-13-decanoyl phorbol,designated as compound 3c,exhibited the most potent anti-HIV-1 activity(EC_(50)2.9 nmol·L^(−1),CC50/EC_(50)11117.24)and significantly inhibited the formation of syncytium(EC_(50)7.0 nmol·L^(−1),CC50/EC_(50)4891.43).Moreover,compound 3c is hypothesized to act both as an HIV-1 entry inhibitor and as an HIV-1 reverse transcriptase inhibitor.Isothermal titration calorimetry and molecular docking studies indicated that compound 3c may also function as a natural activator of protein kinase C(PKC).Therefore,compound 3c emerges as a potential candidate for developing new anti-HIV drugs.展开更多
文摘A new simple method in which arbitrary transfer function matrix is realized withactive multiple port network instead of computer simulating is proposed. The active multipleport network is carried on through state feedback and state cross output for RC ladder network.The main process is to determine coefficients of each adder. Finally, an example is given forillustration.
基金This project is jointly supported by the National Nature Science Foundation of China (Grant No. 60074034) and the Foundation for
文摘Presents analytic criteria for the local activity theory in two-port cellularneural network (CNN) cells with four local state variables, and gives the application to a smoothedChua's circuit (SCC) CNN with two-port and I 5 S 15 arrays. The bifurcation diagrams of the SCC CNNshow that they are completely the same as those of an SCC CNN with one-port calculated earlier;which do not exist locally passive domain. The evolution of the patterns of the state variables ofthe SCC CNN is stimulated. Oscillatory patterns, chaotic patterns, or divergent patterns may emergeif the selected cell parameters are located in the locally active unstable domains but nearby theedge of chaos domain.
文摘The study examined the impacts of urbanization-related activities on soil quality in Port Harcourt Metropolis-Rivers state,Nigeria.Experimental and survey research designs were implored in the study utilizing GIS and spatial analysis approaches.Both primary and secondary sources of data were used.The primary data were generated through laboratory analysis of soil samples from 15 randomly selected sites within the metropolis;and 800 valid copies of socio-economic questionnaire administered to 800 respondents.Also,public hospitals were visited to ascertain the commonest soil borne diseases in the area.Four research questions,four specific objectives and two hypotheses guided the study.The hypotheses were tested with one sample t-test and one sample chi square using SPSS.Standard scientific and laboratory procedures were followed in the collection and analysis of soil samples.Findings of the study include:urbanization-related activities(e.g.waste dumpsites,mechanic workshops,abattoirs,etc.)cause significant changes on soil quality in the area;and this result to the emergence of soil borne diseases(e.g.Vascular witts,Ascaris lumbricoids,Trichuris trichiura,Strongloids stereoralis)which affects residents’wellbeing.However,there is significant difference in the perceived socio-economic effects of the diseases across the area.Specifically,laboratory results for soil analysis show that(mean values):pH 7.22,temperature 25.62℃,PO_(4)0.342 mg/kg,Pb 120.62 mg/kg,K 66.81 mg/kg,NO_(3)mg/kg.The study recommended for enforcement of physical planning and development control laws;regular evaluation of the quality of the soil,and restriction on the location of mechanic workshops and waste dumpsites around the metropolis.
基金supported by the Youth Innovation Promotion Association CAS (2017085)geological survey program of Agriculture, Fisheries and Conservation Department of Hong Kong Special Administrative Region (AFCD/SQ/92/14)
文摘The Port Island Formation(PIF), a typical Cretaceous red bed in Hong Kong, is dominated by non-fossiliferous, reddish clastic rocks, making it difficult to determine the sedimentary age of PIF precisely. Previous studies assigned the PIF to Late Cretaceous provisionally only on the basis of its stratigraphic sequence and lithology. This study identified a tuffite interlayer in the PIF and a zircon UPb age of 128.2±2.7 Ma by LA-ICP-MS method was obtained. It’s the first time to date the depositional age of the PIF with a reliable chronological constraint. With the support of stratigraphic evidence, we concluded that the geological age of PIF should be Early Cretaceous rather than Late Cretaceous. Based on the volcanic history of Hong Kong and Southeast China and the distribution of the PIF in Mirs Bay, it is believed that there was no volcanic activity in Hong Kong in ca. 128 Ma. The tuffite interlayer discovered in PIF was formed by the deposition of volcanic ash, which might originate from remote region outside Hong Kong, in an aquatic environment on Port Island. The identification of the tuffite interlayer, as the response to a volcanic event, has great significance not only to the studies of establishment and regional correlation of the strata system and the geological evolution in Hong Kong,but also to the study of volcanic activities in Southeast China.
基金supported from the National Natural Science Foundation of China (No. 20971056)
文摘The monofunctional substitution reactions between trans-[PtCl（H2O）（NH3）（pip）]＋,trans-[Pt（H2O）2（NH3）（pip）]2＋,trans-[PtCl（H2O）（pip）2]＋,trans-[Pt（H2O）2（pip）2]2＋ （pip = piperidine） and adenine/guanine nucleotides are explored by using B3LYP hybrid functional and IEF-PCM salvation models. For the trans-[Pt（H2O）2（NH3）（pip）]2＋ and trans-[PtCl（H2O）（NH3）（pip）]＋ complexes,the computed barrier heights in aqueous solution are 13.5/13.5 and 11.6/11.6 kcal/mol from trans-Pt-chloroaqua complex to trans/cis-monoadduct for adenine and guanine,and the corresponding values are 20.7/20.7 and 18.8/18.8 kcal/mol from trans-Pt-diaqua complex to trans/cis-monoadduct for adenine and guanine,respectively. For trans-[PtCl（H2O）（pip）2]＋ and trans-[Pt（H2O）2（pip）2]2＋,the corresponding values are 21.5/21.3 and 19.4/19.4 kcal/mol,and 26.0/26.0 and 20.7/20.8 kal/mol for adenine and guanine,respectively. Our calculations demonstrate that the barrier heights of chloroaqua are lower than the corresponding values of diaqua for adenine and guanine. In addition,the free energies of activation for guanine in aqueous solution are all smaller than that for adenine,which predicts a preference of 1.9 kcal/mol when trans-[PtCl（H2O）（NH3）（pip）]＋ and trans-[Pt（H2O）2（NH3）（pip）]2＋ are the active agents and ～1.9 and ～ 5.3 kcal/mol when trans-[PtCl（H2O）（pip）2]＋ and trans-[Pt（H2O）2（pip）2]2＋ are the active agents,respectively. For the reaction of trans-Pt-chloroaqua （or diaqua） to cis-monoadduct,we obtain the same transition-state structure as from the reaction of trans-Pt-chloroaqua （or diaqua） to trans-monoadduct,which seems that the trans-Pt-chloroaqua （or diaqua） complex can generate trans-or cis-monoadduct via the same transition-state.
文摘作为一种适应高比例分布式新能源接入的新型配电网架构,蜂巢状有源配电网利用多端口能量枢纽(multi-port energy hub,MEH)可实现多微电网/配网单元间功率的互联互济,如MEH中包含储能设备,可以进一步提升新能源利用率和电网可靠性。文中提出一种含储能的MEH及其分层协调控制策略。上层控制根据储能系统的荷电状态和配电网运行状态协调控制储能变流器与各并网端口变流器之间的功率分配,使得MEH在平抑新能源波动、配网故障恢复等运行模式下均能够对内部储能系统进行能量管理。下层控制通过将储能变流器有功功率的微分值反馈至储能系统控制环路进行补偿,提高储能变流器输入/输出有功功率响应速度。文中设计了MEH控制系统关键参数,利用MATLAB/Simulink对MEH在配电系统中的应用进行仿真。不同工况下的仿真对比验证了所提分层协调控制策略的有效性,证明该策略能够延长储能系统工作时间,提高储能系统有功功率变化率,减小直流母线的电压波动。
基金supported by the National Natural Science Foundation of China(Nos.81202882,82060670)Suzhou Science and Technology Planning Project in Jiangsu Province of China(No.SNG2021022)+1 种基金the Priority Academic Program Development of the Jiangsu Higher Education Institutes,China(PAPD)and the Project of Innovative Research Team of Yunnan Province(No.202005AE160005).
文摘In this study,37 derivatives of phorbol esters were synthesized and their anti-HIV-1 activities evaluated,building upon our previous synthesis of 51 phorbol derivatives.12-Para-electron-acceptor-trans-cinnamoyl-13-decanoyl phorbol derivatives stood out,demonstrating remarkable anti-HIV-1 activities and inhibitory effects on syncytia formation.These derivatives exhibited a higher safety index compared with the positive control drug.Among them,12-(trans-4-fluorocinnamoyl)-13-decanoyl phorbol,designated as compound 3c,exhibited the most potent anti-HIV-1 activity(EC_(50)2.9 nmol·L^(−1),CC50/EC_(50)11117.24)and significantly inhibited the formation of syncytium(EC_(50)7.0 nmol·L^(−1),CC50/EC_(50)4891.43).Moreover,compound 3c is hypothesized to act both as an HIV-1 entry inhibitor and as an HIV-1 reverse transcriptase inhibitor.Isothermal titration calorimetry and molecular docking studies indicated that compound 3c may also function as a natural activator of protein kinase C(PKC).Therefore,compound 3c emerges as a potential candidate for developing new anti-HIV drugs.
