Based on several books on English teaching and learning,this paper gives a general review on task-based teaching.Firstly,it introduces the definitions of task and task-based syllabus and makes two distinctions,namely,...Based on several books on English teaching and learning,this paper gives a general review on task-based teaching.Firstly,it introduces the definitions of task and task-based syllabus and makes two distinctions,namely,"task"and"activity","taskbased teaching"and"communicative teaching".Then it states the notions behind the task-based teaching.Finally,it gives the notes for the application of this approach.展开更多
New series of pyrazolo[1,5-α]pyrimidine derivatives 7a-i,11a-c and Schiff bases 13a-c were synthesized and screened for their in vitro antitumor activity against three human carcinoma cell lines,namely colorectal car...New series of pyrazolo[1,5-α]pyrimidine derivatives 7a-i,11a-c and Schiff bases 13a-c were synthesized and screened for their in vitro antitumor activity against three human carcinoma cell lines,namely colorectal carcinoma(HCT116),prostate adenocarcinoma(PC-3) and liver carcinoma(HepG-2) using MTT cytotoxicity assay at 100 μg/mL.Some of the tested compounds displayed good anticancer activities against HCT-116 and PC-3 cells.Whereas,compounds 7d and 11 a showed better antitumor activity than the rest of the compounds against both cell lines.A structure-activity relationship(SAR) has been discussed and structures of the newly synthesized compounds were confirmed by different spectral data(MS,IR,^1H NMR and ^13C NMR) and elemental analysis.展开更多
文摘Based on several books on English teaching and learning,this paper gives a general review on task-based teaching.Firstly,it introduces the definitions of task and task-based syllabus and makes two distinctions,namely,"task"and"activity","taskbased teaching"and"communicative teaching".Then it states the notions behind the task-based teaching.Finally,it gives the notes for the application of this approach.
文摘New series of pyrazolo[1,5-α]pyrimidine derivatives 7a-i,11a-c and Schiff bases 13a-c were synthesized and screened for their in vitro antitumor activity against three human carcinoma cell lines,namely colorectal carcinoma(HCT116),prostate adenocarcinoma(PC-3) and liver carcinoma(HepG-2) using MTT cytotoxicity assay at 100 μg/mL.Some of the tested compounds displayed good anticancer activities against HCT-116 and PC-3 cells.Whereas,compounds 7d and 11 a showed better antitumor activity than the rest of the compounds against both cell lines.A structure-activity relationship(SAR) has been discussed and structures of the newly synthesized compounds were confirmed by different spectral data(MS,IR,^1H NMR and ^13C NMR) and elemental analysis.