Aim: To observe the therapeutic effect of acupoint catgut embedding in the treatment of epilepsy rats. Methods: 40 Wistar rats were randomly and evenly divided into normal control, model, medication (Natrii Valproas s...Aim: To observe the therapeutic effect of acupoint catgut embedding in the treatment of epilepsy rats. Methods: 40 Wistar rats were randomly and evenly divided into normal control, model, medication (Natrii Valproas syrup), and catgut embedding groups. Epilepsy model was established by intraperitoneal injection of sodium penicillin (0.4 mu/100 g), twice every week, continuously for 4 weeks. Electroencephalograph (EEG) was used as the index for assessing the effect of catgut embedding on epilepsy. Results: In epilepsy rats of model group, the amplitude and frequency of EEG increased significantly in comparison with control group (P<0.05). While the amplitude and frequency of EEG of catgut embedding group and medication group were all significantly lower than those of model group (P<0.05, 0.01). The frequency of EEG of catgut embedding group was significantly lower than that of medication group (P<0.05). These findings show that both acupoint catgut embedding and medication can apparently improve epileptic electrical activities of the brain in the rat, and the effect of catgut embedding is better than that of medication in lowering the frequency of EEG.展开更多
In the present paper,the clinical curative effects of catgut embedding therapyand traditional acupuncture therapy for treatment of lumbar muscle strain were compared.The sameacupoints were used in both groups.Results ...In the present paper,the clinical curative effects of catgut embedding therapyand traditional acupuncture therapy for treatment of lumbar muscle strain were compared.The sameacupoints were used in both groups.Results showed that the effective rates were 100% and 92.5%respectively in 80 cases of the catgut embedding group and 40 cases of the acupuncture group.Therewas a significant difference between the two groups(P【0.005).It indicates that the catgut embed-ding therapy is an effective method for treatment of lumbar muscle strain.展开更多
Objective:To evaluate the effectiveness and safety of acupoint catgut embedding(ACE)in combination with Chinese herbal medicine(CHM)in treating chronic urticaria(CU).Methods:We thoroughly searched Embase,PubMed,Cochra...Objective:To evaluate the effectiveness and safety of acupoint catgut embedding(ACE)in combination with Chinese herbal medicine(CHM)in treating chronic urticaria(CU).Methods:We thoroughly searched Embase,PubMed,Cochrane Library,Web of Science,China National Knowledge Infrastructure(CNKI),Wangfang database,Chinese Scientific Journal Database(VIP),and Chinese biomedical literature database(SinoMed)for relevant studies from inception until May 2022.Randomized controlled trials(RCTs)on ACE combined with CHM for CU were included.Literature search,data extraction,and risk of bias assessment were independently conducted by two authors.Results:A total of 15 RCTs with 1065 participants were included in this review.Five trials reported that the combined therapy showed a higher total effective rate,and four trials reported that the combined therapy was associated with a lower level of serum immunoglobulin E.Furthermore,two,four,and four trials reported that the combined therapy was more effective in reducing itching degree,size,and number of wheals,respectively.The combined therapy was reported to be associated with a lower recurrence rate in three trials,and with a fewer adverse reaction rate in two trials.Conclusions:ACE in combination with CHM appears to be a safe and effective therapy for patients with CU.Given the relatively low quality of the included trials,these findings should be interpreted cautiously.Further high-quality RCTs are needed to confirm our findings.展开更多
Background:Obesity,as an epidemic public health issue in the world today,not only brings a heavy medical burden to society but also seriously affects people’s quality of life.In the context of new evidence for the ef...Background:Obesity,as an epidemic public health issue in the world today,not only brings a heavy medical burden to society but also seriously affects people’s quality of life.In the context of new evidence for the efficacy of acupoint catgut embedding(ACE)in abdominal obesity(AO),it is necessary to elucidate the mechanism of ACE for AO.The intestinal flora is closely associated with obesity,and the study of its intestinal flora may provide evidence to clarify the mechanism of obesity treatment by ACE.Methods:75 participants will be recruited in this study,including 60 eligible female patients diagnosed with AO and 15 healthy female participants.60 female AO patients will be randomized to ACE group,sham ACE group,and waiting list(WL)group in a ratio of 1:1:1.Patients in two ACE groups will receive one ACE treatment per week for 12 consecutive weeks,and in the WL group will not receive any treatment;only their data will be extracted.The primary outcome is the mean change in body mass index.Secondary effects include waist circumference,body weight,the visual analog score of appetite,and the Gastrointestinal Symptom Rating Scale.High-throughput 16S ribosomal ribonucleic acid gene sequencing will be used to detect intestinal flora in each group before and after the intervention.Conclusion:The results of this trial are expected to identify the critical intestinal flora causing AO and the target intestinal flora of AO regulated by ACE,providing further theoretical support for ACE in the clinical treatment of obesity.展开更多
OBJECTIVE:To explore the difference of catgut embedding effect between acupoints and non-acupoints in patients with abdominal obesity(AO).METHODS:In this multicenter,double-blind,randomized controlled trial,all subjec...OBJECTIVE:To explore the difference of catgut embedding effect between acupoints and non-acupoints in patients with abdominal obesity(AO).METHODS:In this multicenter,double-blind,randomized controlled trial,all subjects were randomly assigned into the acupoint catgut embedding(ACE)group and control group(catgut embedding at non-acupoints).With a 12-week actual intervention period and a 4-week period of follow-up.Waist circumference(WC),body weight,body mass index(BMI),hip circumference(HC)and appetite were applied and assessed at baseline and after 6,12 and 16 weeks.RESULTS:After the total intervention phase(12 weeks),the WC,body weight,BMI,HC and visual analogue scale scores of appetite,decreased significantly in the two groups as compared to the baseline(P<0.001).Meanwhile,after the 4-week follow-up,the indicators still decreased significantly in the ACE group(P<0.001).At 12 and 16 weeks,catgut embedding at acupoints showed significantly advantages to non-acupoints in WC and appetite(P<0.05).No serious adverse events were observed in ACE group and control group.CONCLUSIONS:Catgut embedding at acupoints and non-acupoints are all effective and safe for AO.ACE can effectively treat AO as expected and deliver lasting results.展开更多
OBJECTIVE:To assess the efficacy of acupoint catgut embedding(ACE)for simple obesity in preclinical animal experiments.METHODS:We searched the following 14 electronic databases:PubM ed,Cochrane Library,EMBASE,Oriental...OBJECTIVE:To assess the efficacy of acupoint catgut embedding(ACE)for simple obesity in preclinical animal experiments.METHODS:We searched the following 14 electronic databases:PubM ed,Cochrane Library,EMBASE,Oriental Medicine Advanced Searching Integrated System,KoreaMed,Korean Studies Information Service System,Science-on,Research Information Sharing Service,Korea Citation Index,Korea Traditional Knowledge Portal,China Network Knowledge Infrastructure Database,Wanfang Database,Chinese Science and Technology Journal Database,and Chinese Biology Medicine Database,from inception to November 2021 without language limitation.The assessment was performed according to the guidelines of Animal Research:Reporting of in vivo experiments;and Metaanalysis was performed using Reviewer Manager 5.4.1 software.RESULTS:Twenty-four studies involving 813 animals were selected.Meta-analysis showed that ACE was beneficial for weight control[n=40,MD=-50.63,95%CI(-57.59,-43.67),P<0.00001,I 2=0%]and reduced the Lee index[n=40,MD=-18.79,95%CI(-20.01,-17.57),P<0.00001,I 2=0%].However,when efficacy of ACE was compared with that of manual acupuncture,electroacupuncture,or oilistat therapy,statistical difference was not observed between the two groups.CONCLUSIONS:This systematic review suggests that ACE may be efficacious in treating obesity.Moreover,the analyses highlighted the necessity to perform welldesigned,higher-quality experiments.展开更多
Acupoint catgut embedding therapy(ACET),filling the gaps of traditional Chinese medicine acupuncture treatment,has been widely used for the treatment of many diseases with significant effects.The aim of this paper is ...Acupoint catgut embedding therapy(ACET),filling the gaps of traditional Chinese medicine acupuncture treatment,has been widely used for the treatment of many diseases with significant effects.The aim of this paper is to obtain polyglycollide acid(PGA)fibers with higher performance at a lower cost,and ensure that PGA can meet the clinical requirements as well.PGA fibers with different diameters were spun as embedding materials.The mechanical performance,thermodynamic and biodegradable properties of PGA fibers were studied under different spinning process parameters,including spinning speed,drawing temperature and stretching ratio.The experimental results showed that the optimum spinning parameters were the spinning speed at 150 m/min,the drawing temperature of 45 ℃,and the stretching ratio of 4.0.The initial modulus of PGA fibers was 3.876 N/tex.The crystallization degree was 68% and the degradation performance was in consistent with treatment cycle of patients.展开更多
It is reported that 245 cases of peptic ulcer were treated with catgut implantationat Pishu（BL 20）-through-Weishu（BL 21）,Shangwan（CV 13）-through-Xiawan（CV 10）and Zusanli（ST 36）points.Catgut was embedded subc...It is reported that 245 cases of peptic ulcer were treated with catgut implantationat Pishu（BL 20）-through-Weishu（BL 21）,Shangwan（CV 13）-through-Xiawan（CV 10）and Zusanli（ST 36）points.Catgut was embedded subcutaneously and left for 15 days as a course.As a resuit,121 cases（49.39％）were cured and 124（50.61％）improved.The total effective was 100％.展开更多
Objective:To explore the clinical effect of embedding thread combined with Jianpi Qushi Huayu ointment in the treatment of bronchiectasis in remission period,and to observe the effect on the level of inflammatory cyto...Objective:To explore the clinical effect of embedding thread combined with Jianpi Qushi Huayu ointment in the treatment of bronchiectasis in remission period,and to observe the effect on the level of inflammatory cytokines.Methods:150 patients with bronchiectasis in remission period were divided into three groups(50 cases in each group),western medicine group(treated with salmeterol fluticasone and low dose erythromycin),combined group(treated with Jianpi Qushi Huayu plaster),observation group(treated with western medicine+Jianpi Qushi Huayu plaster+embedding thread),and the clinical treatment of the three groups were compared.Result:before and after treatment,the improvement of TCM syndrome score,the improvement of pulmonary ventilation index,the improvement of inflammatory cytokines,and the change of adverse reactions.Results:the treatment efficiency of the observation group and the combination group was significantly higher than that of the western medicine group P The peak level of expiratory flow velocity,the maximum expiratory flow,the forced expiratory volume in one second and the ratio of forced expiratory volume in one second to vital capacity in the observation group and the combined group were significantly better than those in the western medicine group and the pre-treatment level(P<0.05),and the improvement in the observation group was better than that in the combined group After treatment,the expression of IL-13,IL-10 and IL-4 in the combined group was significantly better than that in the western medicine group and before treatment(P<0.05),and the improvement in the observation group was better than that in the combined group;there was no significant difference in the incidence of adverse reactions among the three groups(P>0.05).Conclusion:catgut embedding combined with Jianpi Qushi Huayu ointment can significantly alleviate the related clinical symptoms and signs,effectively control the further aggravation of the disease,improve the lung function of patients,regulate the level of inflammatory cytokines to reduce the degree of inflammatory reaction,and do not significantly aggravate the adverse reactions of drugs.展开更多
Objective: To observe the therapeutic effect of bloodletting plus point implantation of catgut in the treatment of 67 cases of vascular headache. Methods: A total of 107 cases of vascular headache patients were divide...Objective: To observe the therapeutic effect of bloodletting plus point implantation of catgut in the treatment of 67 cases of vascular headache. Methods: A total of 107 cases of vascular headache patients were divided into treatment group (n=67) and control group (n=40). Bilateral Taiyang (EX-HN 5) and Jiaosun (TE 20) were pricked with a needle to let a little blood out, once every 4 days. Bilateral Fengmen (BL 12) and Ganshu (BL 18) were used for embedding catgut, once every 16 days. Patients of control group were ordered to take Rotunding, Oryzanol and Nimodipine, 3 times daily. Results: After 16 days’ treatment, of the 67 cases in treatment group, 26 were cured, 37 responded with improvement in their symptoms and 4 failed; while of the 40 cases in control group, 10 were cured, 19 responded with improvement in their symptoms and 11 failed. The total effective rate of treatment group was significantly superior to that of control group (P<0.01). In addition, the time of headache disappearance of treatment group was strikingly shorter than that of control group; while the duration of sleep of treatment group was strikingly longer than that of control group (P<0.01). Conclusion: The therapeutic effect of acupoint bloodletting plus acupoint embedding of catgut is superior to that of Western medicine in the treatment of vascular headache.展开更多
文摘Aim: To observe the therapeutic effect of acupoint catgut embedding in the treatment of epilepsy rats. Methods: 40 Wistar rats were randomly and evenly divided into normal control, model, medication (Natrii Valproas syrup), and catgut embedding groups. Epilepsy model was established by intraperitoneal injection of sodium penicillin (0.4 mu/100 g), twice every week, continuously for 4 weeks. Electroencephalograph (EEG) was used as the index for assessing the effect of catgut embedding on epilepsy. Results: In epilepsy rats of model group, the amplitude and frequency of EEG increased significantly in comparison with control group (P<0.05). While the amplitude and frequency of EEG of catgut embedding group and medication group were all significantly lower than those of model group (P<0.05, 0.01). The frequency of EEG of catgut embedding group was significantly lower than that of medication group (P<0.05). These findings show that both acupoint catgut embedding and medication can apparently improve epileptic electrical activities of the brain in the rat, and the effect of catgut embedding is better than that of medication in lowering the frequency of EEG.
文摘In the present paper,the clinical curative effects of catgut embedding therapyand traditional acupuncture therapy for treatment of lumbar muscle strain were compared.The sameacupoints were used in both groups.Results showed that the effective rates were 100% and 92.5%respectively in 80 cases of the catgut embedding group and 40 cases of the acupuncture group.Therewas a significant difference between the two groups(P【0.005).It indicates that the catgut embed-ding therapy is an effective method for treatment of lumbar muscle strain.
基金This research was supported by Key Research Program of the Chinese Academy of Sciences(ZDRW-ZS-2021-1-2).
文摘Objective:To evaluate the effectiveness and safety of acupoint catgut embedding(ACE)in combination with Chinese herbal medicine(CHM)in treating chronic urticaria(CU).Methods:We thoroughly searched Embase,PubMed,Cochrane Library,Web of Science,China National Knowledge Infrastructure(CNKI),Wangfang database,Chinese Scientific Journal Database(VIP),and Chinese biomedical literature database(SinoMed)for relevant studies from inception until May 2022.Randomized controlled trials(RCTs)on ACE combined with CHM for CU were included.Literature search,data extraction,and risk of bias assessment were independently conducted by two authors.Results:A total of 15 RCTs with 1065 participants were included in this review.Five trials reported that the combined therapy showed a higher total effective rate,and four trials reported that the combined therapy was associated with a lower level of serum immunoglobulin E.Furthermore,two,four,and four trials reported that the combined therapy was more effective in reducing itching degree,size,and number of wheals,respectively.The combined therapy was reported to be associated with a lower recurrence rate in three trials,and with a fewer adverse reaction rate in two trials.Conclusions:ACE in combination with CHM appears to be a safe and effective therapy for patients with CU.Given the relatively low quality of the included trials,these findings should be interpreted cautiously.Further high-quality RCTs are needed to confirm our findings.
基金supported by The Youth Special of Yunnan Province Ten-thousand Plan(YNWR-QNBJ-2019-257)the Human Resources and Social Security Department of Yunnan Province and Yunnan Provincial Science Plan Project-Joint of Traditional Chinese Medicine(2017FF117-011,2019FF002-021,202101AZ070001-096)the Science&Technology Department of Yunnan Province.
文摘Background:Obesity,as an epidemic public health issue in the world today,not only brings a heavy medical burden to society but also seriously affects people’s quality of life.In the context of new evidence for the efficacy of acupoint catgut embedding(ACE)in abdominal obesity(AO),it is necessary to elucidate the mechanism of ACE for AO.The intestinal flora is closely associated with obesity,and the study of its intestinal flora may provide evidence to clarify the mechanism of obesity treatment by ACE.Methods:75 participants will be recruited in this study,including 60 eligible female patients diagnosed with AO and 15 healthy female participants.60 female AO patients will be randomized to ACE group,sham ACE group,and waiting list(WL)group in a ratio of 1:1:1.Patients in two ACE groups will receive one ACE treatment per week for 12 consecutive weeks,and in the WL group will not receive any treatment;only their data will be extracted.The primary outcome is the mean change in body mass index.Secondary effects include waist circumference,body weight,the visual analog score of appetite,and the Gastrointestinal Symptom Rating Scale.High-throughput 16S ribosomal ribonucleic acid gene sequencing will be used to detect intestinal flora in each group before and after the intervention.Conclusion:The results of this trial are expected to identify the critical intestinal flora causing AO and the target intestinal flora of AO regulated by ACE,providing further theoretical support for ACE in the clinical treatment of obesity.
基金Yunnan Expert Workstation-Liang Fanrong Station:Study and Transformation of Classical Syndrome Differentiation System on Acupuncture and Moxibustion(No.202305AF150072)Yunnan Province Ten-thousand Plan:Youth Special-Guo Taipin(No.YNWR-QNBJ-2019-257)+2 种基金Yunnan Provincial Science Project:Study on the Bidirectional Regulation Mechanism of Central Network of ShuMu Catgut Embedding in Abdominal Obesity of Stomach Heat-Spleen Deficiency Type Which based on Multimodal Technique(No.2017FF117-011)Study on the Central Mechanism of Synergistic Potentiation of Shu-Mu Catgut Embedding in Abdominal Obesity(No.2019FF002-021)Study on the Brain Network Mechanism of Shu-Mu Catgut Embedding in Abdominal Obesity which based on Multi-Modal Technique(No.202101AZ070001-096)。
文摘OBJECTIVE:To explore the difference of catgut embedding effect between acupoints and non-acupoints in patients with abdominal obesity(AO).METHODS:In this multicenter,double-blind,randomized controlled trial,all subjects were randomly assigned into the acupoint catgut embedding(ACE)group and control group(catgut embedding at non-acupoints).With a 12-week actual intervention period and a 4-week period of follow-up.Waist circumference(WC),body weight,body mass index(BMI),hip circumference(HC)and appetite were applied and assessed at baseline and after 6,12 and 16 weeks.RESULTS:After the total intervention phase(12 weeks),the WC,body weight,BMI,HC and visual analogue scale scores of appetite,decreased significantly in the two groups as compared to the baseline(P<0.001).Meanwhile,after the 4-week follow-up,the indicators still decreased significantly in the ACE group(P<0.001).At 12 and 16 weeks,catgut embedding at acupoints showed significantly advantages to non-acupoints in WC and appetite(P<0.05).No serious adverse events were observed in ACE group and control group.CONCLUSIONS:Catgut embedding at acupoints and non-acupoints are all effective and safe for AO.ACE can effectively treat AO as expected and deliver lasting results.
基金the Korea Institute of Oriental Medicine(Grant No.KSN1823211 and KSN20234115)。
文摘OBJECTIVE:To assess the efficacy of acupoint catgut embedding(ACE)for simple obesity in preclinical animal experiments.METHODS:We searched the following 14 electronic databases:PubM ed,Cochrane Library,EMBASE,Oriental Medicine Advanced Searching Integrated System,KoreaMed,Korean Studies Information Service System,Science-on,Research Information Sharing Service,Korea Citation Index,Korea Traditional Knowledge Portal,China Network Knowledge Infrastructure Database,Wanfang Database,Chinese Science and Technology Journal Database,and Chinese Biology Medicine Database,from inception to November 2021 without language limitation.The assessment was performed according to the guidelines of Animal Research:Reporting of in vivo experiments;and Metaanalysis was performed using Reviewer Manager 5.4.1 software.RESULTS:Twenty-four studies involving 813 animals were selected.Meta-analysis showed that ACE was beneficial for weight control[n=40,MD=-50.63,95%CI(-57.59,-43.67),P<0.00001,I 2=0%]and reduced the Lee index[n=40,MD=-18.79,95%CI(-20.01,-17.57),P<0.00001,I 2=0%].However,when efficacy of ACE was compared with that of manual acupuncture,electroacupuncture,or oilistat therapy,statistical difference was not observed between the two groups.CONCLUSIONS:This systematic review suggests that ACE may be efficacious in treating obesity.Moreover,the analyses highlighted the necessity to perform welldesigned,higher-quality experiments.
基金“111 Project” Biomedical Textile Materials Science and Technology,China(No.B07024)
文摘Acupoint catgut embedding therapy(ACET),filling the gaps of traditional Chinese medicine acupuncture treatment,has been widely used for the treatment of many diseases with significant effects.The aim of this paper is to obtain polyglycollide acid(PGA)fibers with higher performance at a lower cost,and ensure that PGA can meet the clinical requirements as well.PGA fibers with different diameters were spun as embedding materials.The mechanical performance,thermodynamic and biodegradable properties of PGA fibers were studied under different spinning process parameters,including spinning speed,drawing temperature and stretching ratio.The experimental results showed that the optimum spinning parameters were the spinning speed at 150 m/min,the drawing temperature of 45 ℃,and the stretching ratio of 4.0.The initial modulus of PGA fibers was 3.876 N/tex.The crystallization degree was 68% and the degradation performance was in consistent with treatment cycle of patients.
文摘It is reported that 245 cases of peptic ulcer were treated with catgut implantationat Pishu（BL 20）-through-Weishu（BL 21）,Shangwan（CV 13）-through-Xiawan（CV 10）and Zusanli（ST 36）points.Catgut was embedded subcutaneously and left for 15 days as a course.As a resuit,121 cases（49.39％）were cured and 124（50.61％）improved.The total effective was 100％.
基金2020 Hebei provincial research project of Chinese medicine(No.2020374)
文摘Objective:To explore the clinical effect of embedding thread combined with Jianpi Qushi Huayu ointment in the treatment of bronchiectasis in remission period,and to observe the effect on the level of inflammatory cytokines.Methods:150 patients with bronchiectasis in remission period were divided into three groups(50 cases in each group),western medicine group(treated with salmeterol fluticasone and low dose erythromycin),combined group(treated with Jianpi Qushi Huayu plaster),observation group(treated with western medicine+Jianpi Qushi Huayu plaster+embedding thread),and the clinical treatment of the three groups were compared.Result:before and after treatment,the improvement of TCM syndrome score,the improvement of pulmonary ventilation index,the improvement of inflammatory cytokines,and the change of adverse reactions.Results:the treatment efficiency of the observation group and the combination group was significantly higher than that of the western medicine group P The peak level of expiratory flow velocity,the maximum expiratory flow,the forced expiratory volume in one second and the ratio of forced expiratory volume in one second to vital capacity in the observation group and the combined group were significantly better than those in the western medicine group and the pre-treatment level(P<0.05),and the improvement in the observation group was better than that in the combined group After treatment,the expression of IL-13,IL-10 and IL-4 in the combined group was significantly better than that in the western medicine group and before treatment(P<0.05),and the improvement in the observation group was better than that in the combined group;there was no significant difference in the incidence of adverse reactions among the three groups(P>0.05).Conclusion:catgut embedding combined with Jianpi Qushi Huayu ointment can significantly alleviate the related clinical symptoms and signs,effectively control the further aggravation of the disease,improve the lung function of patients,regulate the level of inflammatory cytokines to reduce the degree of inflammatory reaction,and do not significantly aggravate the adverse reactions of drugs.
文摘Objective: To observe the therapeutic effect of bloodletting plus point implantation of catgut in the treatment of 67 cases of vascular headache. Methods: A total of 107 cases of vascular headache patients were divided into treatment group (n=67) and control group (n=40). Bilateral Taiyang (EX-HN 5) and Jiaosun (TE 20) were pricked with a needle to let a little blood out, once every 4 days. Bilateral Fengmen (BL 12) and Ganshu (BL 18) were used for embedding catgut, once every 16 days. Patients of control group were ordered to take Rotunding, Oryzanol and Nimodipine, 3 times daily. Results: After 16 days’ treatment, of the 67 cases in treatment group, 26 were cured, 37 responded with improvement in their symptoms and 4 failed; while of the 40 cases in control group, 10 were cured, 19 responded with improvement in their symptoms and 11 failed. The total effective rate of treatment group was significantly superior to that of control group (P<0.01). In addition, the time of headache disappearance of treatment group was strikingly shorter than that of control group; while the duration of sleep of treatment group was strikingly longer than that of control group (P<0.01). Conclusion: The therapeutic effect of acupoint bloodletting plus acupoint embedding of catgut is superior to that of Western medicine in the treatment of vascular headache.
