Refined rhubarb tablets were used to treat 182 cases of acute hemorrhaging of the upperdigestive tract with a total effective rate of 96. 1 % and an average hemostatic time ot 2. 8 days. Prospec-tive and double blind ...Refined rhubarb tablets were used to treat 182 cases of acute hemorrhaging of the upperdigestive tract with a total effective rate of 96. 1 % and an average hemostatic time ot 2. 8 days. Prospec-tive and double blind comparative studies of the drug revealed that it had a rernarkably higher hemostaticeffect than compound western medicines (P<0. 01) and was superior to crude rhubarb, which usuallycaused nausea and vomiting and had unstable therapeutic effects- Acute and subacute toxicity determina-tions. genetic toxicologic tests, as well as determinations of various indexes ot blood vessels, pepsin.blood rheology, platelets, bleeding and blood coagulation factors were done, suggesting that refinedrhubarb tablets were nontoxic. safe and effective in local hemostasis and general hemodilution-likehemostasis.展开更多
文摘Refined rhubarb tablets were used to treat 182 cases of acute hemorrhaging of the upperdigestive tract with a total effective rate of 96. 1 % and an average hemostatic time ot 2. 8 days. Prospec-tive and double blind comparative studies of the drug revealed that it had a rernarkably higher hemostaticeffect than compound western medicines (P<0. 01) and was superior to crude rhubarb, which usuallycaused nausea and vomiting and had unstable therapeutic effects- Acute and subacute toxicity determina-tions. genetic toxicologic tests, as well as determinations of various indexes ot blood vessels, pepsin.blood rheology, platelets, bleeding and blood coagulation factors were done, suggesting that refinedrhubarb tablets were nontoxic. safe and effective in local hemostasis and general hemodilution-likehemostasis.
文摘目的:比较免疫法粪便隐血试验(immune fecal occult blood test,IFOBT)和化学法粪便隐血试验(chemical fecal occult blood test,CFOBT)在上消化道出血性疾病中的阳性率,以验证IFOBT筛查上消化道出血不具特异性.方法:2006-07/2007-03间连续选择我院内镜中心进行胃镜检查的上消化道出血性疾病患者206例,利用邻甲苯胺CFOBT和IFOBT同时比较两种粪便隐血试验的阳性率,并结合临床资料分析其相应结果.结果:IFOBT和CFOBT结果均与食管癌、胃癌的解剖部位及食管癌浸润深度无关,两者均与胃癌浸润深度有关,与胃癌的最大长径呈正相关(IFOBT:r=0.30,P=0.02:CFOBT:r=0.20,P=0.04);IFOBT与食管癌的最大长径呈正相关(r=0.38,P=0.01);CFOBT在食管癌患者中的阳性率高于食管磷状细胞癌抗原(SCC)的阳性率(47.43% vs 20.45%,P<0.05);两者在胃癌患者中的阳性率均高于CA125,CEA和CA199的阳性率.CFOBT检测胃癌、食管癌、返流性食管炎和消化性溃疡的阳性率均高于IFOBT(50.88% vs 35.09%,47.73% vs 29.55%,18.00% vs 6.00%,60.OO% vs 41.82%,均P<0.05).IFOBT在上消化道出血性疾病中的总阳性率低于CFOBT.结论:IFOBT粪便隐血试验不适合上消化道出血性疾病的筛查,可能对下消化道出血性疾病的筛查具有相对特异性.
