The search for the generating compatibility conditions (CC) of a given operator is a very recent problem met in general relativity in order to study the Killing operator for various standard useful metrics. Accordingl...The search for the generating compatibility conditions (CC) of a given operator is a very recent problem met in general relativity in order to study the Killing operator for various standard useful metrics. Accordingly, this paper can be considered as a natural continuation of a previous paper recently published in JMP under the title Minkowski, Schwarschild and Kerr metrics revisited. In particular, we prove that the intrinsic link existing between the lack of formal exactness of an operator sequence on the jet level, the lack of formal exactness of its corresponding symbol sequence and the lack of formal integrability (FI) of the initial operator is of a purely homological nature as it is based on the long exact connecting sequence provided by the so-called snake lemma in homological algebra. It is therefore quite difficult to grasp it in general and even more difficult to use it on explicit examples. It does not seem that any one of the results presented in this paper is known as most of the other authors who studied the above problem of computing the total number of generating CC are confusing this number with the degree of generality introduced by A. Einstein in his 1930 letters to E. Cartan. One of the motivating examples that we provide is so striking that it is even difficult to imagine that such an example could exist. We hope this paper could be used as a source of testing examples for future applications of computer algebra in general relativity and, more generally, in mathematical physics.展开更多
Satellite observation scheduling plays a significant role in improving the efficiency of satellite observation systems.Although many scheduling algorithms have been proposed,emergency tasks,characterized as importance...Satellite observation scheduling plays a significant role in improving the efficiency of satellite observation systems.Although many scheduling algorithms have been proposed,emergency tasks,characterized as importance and urgency(e.g.,observation tasks orienting to the earthquake area and military conflict area),have not been taken into account yet.Therefore,it is crucial to investigate the satellite integrated scheduling methods,which focus on meeting the requirements of emergency tasks while maximizing the profit of common tasks.Firstly,a pretreatment approach is proposed,which eliminates conflicts among emergency tasks and allocates all tasks with a potential time-window to related orbits of satellites.Secondly,a mathematical model and an acyclic directed graph model are constructed.Thirdly,a hybrid ant colony optimization method mixed with iteration local search(ACO-ILS) is established to solve the problem.Moreover,to guarantee all solutions satisfying the emergency task requirement constraints,a constraint repair method is presented.Extensive experimental simulations show that the proposed integrated scheduling method is superior to two-phased scheduling methods,the performance of ACO-ILS is greatly improved in both evolution speed and solution quality by iteration local search,and ACO-ILS outperforms both genetic algorithm and simulated annealing algorithm.展开更多
In the blockchain,the consensus mechanism plays a key role in maintaining the security and legitimation of contents recorded in the blocks.Various blockchain consensus mechanisms have been proposed.However,there is no...In the blockchain,the consensus mechanism plays a key role in maintaining the security and legitimation of contents recorded in the blocks.Various blockchain consensus mechanisms have been proposed.However,there is no technical analysis and comparison as a guideline to determine which type of consensus mechanism should be adopted in a specific scenario/application.To this end,this work investigates three mainstream consensus mechanisms in the blockchain,namely,Proof of Work(PoW),Proof of Stake(PoS),and Direct Acyclic Graph(DAG),and identifies their performances in terms of the average time to generate a new block,the confirmation delay,the Transaction Per Second(TPS)and the confirmation failure probability.The results show that the consensus process is affected by both network resource(computation power/coin age,buffer size)and network load conditions.In addition,it shows that PoW and PoS are more sensitive to the change of network resource while DAG is more sensitive to network load conditions.展开更多
A new acyclic peroxide derivative asperoxide A(1),along with 13 known compounds,namely,microperfuranone(2),9-hydroxymicroperfuranone(3),gibellulin A(4),lecanoric acid(5),terrequinone A(6),sterigmatocystin(7),isosecost...A new acyclic peroxide derivative asperoxide A(1),along with 13 known compounds,namely,microperfuranone(2),9-hydroxymicroperfuranone(3),gibellulin A(4),lecanoric acid(5),terrequinone A(6),sterigmatocystin(7),isosecosterigmatocystin(8),arugosin C(9),curvularin(10),3,3'-diindolylmethane(11),austinol(12),austin(13),and dehydroaustin(14),were isolated and identified from the culture extract of Aspergillus nidulans SD-531,a fungus obtained from the deep-sea sediment of cold spring in the South China Sea.Their structures were determined based on detailed interpretation of nuclear magnetic resonance(NMR)spectroscopic and mass spectrometry data analysis.All the isolated compounds were evaluated for antimicrobial activities against human and aquatic bacteria as well as plant pathogenic fungi.Compounds 1–8,10,and 11 exhibited antimicrobial activities against some of the tested strains with minimum inhibitory concentration(MIC)values ranging from^2 to 64μg/mL.Compounds 4 and 6 displayed strongest activities among the tested samples and might be used as promising molecules for the development of natural antimicrobial agents.展开更多
By employing a fixed point theorem due to Ding, Park and Jung, some existence theorems of solutions for equilibrium problems with lower and upper bounds are proved in noncompact topological spaces. These results furth...By employing a fixed point theorem due to Ding, Park and Jung, some existence theorems of solutions for equilibrium problems with lower and upper bounds are proved in noncompact topological spaces. These results further answer the open problem raised by Isac, Sehgal and Singh under much weaker assumptions.展开更多
A proper edge coloring of a graph G is called adjacent vertex-distinguishing acyclic edge coloring if there is no 2-colored cycle in G and the coloring set of edges incident with u is not equal to the coloring set of ...A proper edge coloring of a graph G is called adjacent vertex-distinguishing acyclic edge coloring if there is no 2-colored cycle in G and the coloring set of edges incident with u is not equal to the coloring set of edges incident with v, where uv∈ E(G). The adjacent vertex distinguishing acyclic edge chromatic number of G, denoted by X'Aa(G), is the minimal number of colors in an adjacent vertex distinguishing acyclic edge coloring of G. If a graph G has an adjacent vertex distinguishing acyclic edge coloring, then G is called adjacent vertex distinguishing acyclic. In this paper, we obtain adjacent vertex-distinguishing acyclic edge coloring of some graphs and put forward some conjectures.展开更多
In order to solve the problem of efficiently assigning tasks in an ad-hoc mobile cloud( AMC),a task assignment algorithm based on the heuristic algorithm is proposed. The proposed task assignment algorithm based on pa...In order to solve the problem of efficiently assigning tasks in an ad-hoc mobile cloud( AMC),a task assignment algorithm based on the heuristic algorithm is proposed. The proposed task assignment algorithm based on particle swarm optimization and simulated annealing( PSO-SA) transforms the dependencies between tasks into a directed acyclic graph( DAG) model. The number in each node represents the computation workload of each task and the number on each edge represents the workload produced by the transmission. In order to simulate the environment of task assignment in AMC,mathematical models are developed to describe the dependencies between tasks and the costs of each task are defined. PSO-SA is used to make the decision for task assignment and for minimizing the cost of all devices,which includes the energy consumption and time delay of all devices.PSO-SA also takes the advantage of both particle swarm optimization and simulated annealing by selecting an optimal solution with a certain probability to avoid falling into local optimal solution and to guarantee the convergence speed. The simulation results show that compared with other existing algorithms,the PSO-SA has a smaller cost and the result of PSO-SA can be very close to the optimal solution.展开更多
Some new coincidence theorems involving a new class of set-valued mappingscontaining composites of acyclic mappings defined on a contractible space are proved.As applications, some existence theorems of maximal elemen...Some new coincidence theorems involving a new class of set-valued mappingscontaining composites of acyclic mappings defined on a contractible space are proved.As applications, some existence theorems of maximal elements and solutions of abstract variational inequalities, and best approximation theorems are proved. These theorems improve and generalize a number of known results in recent literature.展开更多
Two new isomeric compounds of rare acyclic C13-norisoprenoids, along with two known lignans sauchinone and licarin A, were isolated from the herb of Saururus chinensis (Lour.) Baill. Their structures were elucidated...Two new isomeric compounds of rare acyclic C13-norisoprenoids, along with two known lignans sauchinone and licarin A, were isolated from the herb of Saururus chinensis (Lour.) Baill. Their structures were elucidated on the basis of spectral analysis.展开更多
Based on the key function of version management in PDM system, this paper discusses the function and the realization of version management and the transitions of version states with a workflow. A directed aeyclic grap...Based on the key function of version management in PDM system, this paper discusses the function and the realization of version management and the transitions of version states with a workflow. A directed aeyclic graph is used to describe a version model. Three storage modes of the directed acyelic graph version model in the database, the bumping block and the PDM working memory are presented and the conversion principle of these three modes is given. The study indicates that building a dynamic product structure configuration model based on versions is the key to resolve the problem. Thus a version model of single product object is built. Then the version management model in product structure configuration is built and the application of version management of PDM syster is presented as a case.展开更多
Eight novel heterobinuclear complexes of Ln3+ and Zn2+ with salicylidene diethylene glycol diamine(SALDA) Schiff base (NO3)22H2O(Ln=Pr, Nd, Sm, Gd, Tb, Er, Yb, Y) were synthesized and characterized on the basis of IR...Eight novel heterobinuclear complexes of Ln3+ and Zn2+ with salicylidene diethylene glycol diamine(SALDA) Schiff base (NO3)22H2O(Ln=Pr, Nd, Sm, Gd, Tb, Er, Yb, Y) were synthesized and characterized on the basis of IR and UV, particularly by1H and13C NMR spectra. It is confirmed that the azomethine nitrogen, ethereal oxygen and a part of phenolic oxygen atoms coordinate to the central ions.展开更多
A series of novel L-amino acid esters prodrugs of acyclic nucleoside phosphonates was synthesized and their anti-HBV activity was evaluated in HepG2 2.2.15 cells. Compound 1d exhibited more potent anti-HBV activity an...A series of novel L-amino acid esters prodrugs of acyclic nucleoside phosphonates was synthesized and their anti-HBV activity was evaluated in HepG2 2.2.15 cells. Compound 1d exhibited more potent anti-HBV activity and lower cytotoxicity than those of adefovir dipivoxil with EC50 and CC50 values of 0.207 μmol/L and 2530 μmol/L, respectively.展开更多
Key tactics of origin-based user equilibrium (OUE) algorithm was studied,which involved the algorithm procedure and several implementation issues.To speed up the convergence,update policies of flows,costs and bushes w...Key tactics of origin-based user equilibrium (OUE) algorithm was studied,which involved the algorithm procedure and several implementation issues.To speed up the convergence,update policies of flows,costs and bushes were proposed.The methods of step-size searching and bush construction are proved to be practical.The modified OUE algorithm procedure was also optimized to take the advantage of multi-thread process.Convergence performances were compared with those of other algorithms by different sizes of urban transportation networks.The result shows this modified OUE algorithm is more efficient and consumes less time to achieve the reasonable relative gap in practical applications.展开更多
Based on the framework of support vector machines (SVM) using one-against-one (OAO) strategy, a new multi-class kernel method based on directed aeyclie graph (DAG) and probabilistic distance is proposed to raise...Based on the framework of support vector machines (SVM) using one-against-one (OAO) strategy, a new multi-class kernel method based on directed aeyclie graph (DAG) and probabilistic distance is proposed to raise the multi-class classification accuracies. The topology structure of DAG is constructed by rearranging the nodes' sequence in the graph. DAG is equivalent to guided operating SVM on a list, and the classification performance depends on the nodes' sequence in the graph. Jeffries-Matusita distance (JMD) is introduced to estimate the separability of each class, and the implementation list is initialized with all classes organized according to certain sequence in the list. To testify the effectiveness of the proposed method, numerical analysis is conducted on UCI data and hyperspectral data. Meanwhile, comparative studies using standard OAO and DAG classification methods are also conducted and the results illustrate better performance and higher accuracy of the orooosed JMD-DAG method.展开更多
A new static task scheduling algorithm named edge-zeroing based on dynamic critical paths is proposed. The main ideas of the algorithm are as follows: firstly suppose that all of the tasks are in different clusters; s...A new static task scheduling algorithm named edge-zeroing based on dynamic critical paths is proposed. The main ideas of the algorithm are as follows: firstly suppose that all of the tasks are in different clusters; secondly, select one of the critical paths of the partially clustered directed acyclic graph; thirdly, try to zero one of graph communication edges; fourthly, repeat above three processes until all edges are zeroed; finally, check the generated clusters to see if some of them can be further merged without increasing the parallel time. Comparisons of the previous algorithms with edge-zeroing based on dynamic critical paths show that the new algorithm has not only a low complexity but also a desired performance comparable or even better on average to much higher complexity heuristic algorithms.展开更多
Topomer CoMFA models have been used to optimize the potency of 15 biologically active acridone derivatives se- lected from the literature. Their 3D chemical structures were sliced into three acyclic R groups, to produ...Topomer CoMFA models have been used to optimize the potency of 15 biologically active acridone derivatives se- lected from the literature. Their 3D chemical structures were sliced into three acyclic R groups, to produce a fragment that is present in each training set. The analysis was successful with 3 as the number of components that provided the highest q2 results: q2 is 0.56, which is the cross-validated coefficient for the specified number of components, giving rise to 0.37 standard error of estimate (q2 stderr), and a conventional coefficient (r2) of 0.82, whose standard error of estimate is 0.24. These results provide structure-activity relationship (sar) among the compounds. The result of the To-pomer CoMFA studies was used to design novel derivatives for future studies.展开更多
A proper edge colouring f of a graph G is called acyclic if there are no bichromatic cycles in the graph. The acyclic edge chromatic number or acyclic chromatic index, denoted by , is the minimum number of colours in ...A proper edge colouring f of a graph G is called acyclic if there are no bichromatic cycles in the graph. The acyclic edge chromatic number or acyclic chromatic index, denoted by , is the minimum number of colours in an acyclic edge colouring of G. In this paper, we discuss the acyclic edge colouring of middle, central, total and line graphs of prime related star graph families. Also exact values of acyclic chromatic indices of such graphs are derived and some of their structural properties are discussed.展开更多
文摘The search for the generating compatibility conditions (CC) of a given operator is a very recent problem met in general relativity in order to study the Killing operator for various standard useful metrics. Accordingly, this paper can be considered as a natural continuation of a previous paper recently published in JMP under the title Minkowski, Schwarschild and Kerr metrics revisited. In particular, we prove that the intrinsic link existing between the lack of formal exactness of an operator sequence on the jet level, the lack of formal exactness of its corresponding symbol sequence and the lack of formal integrability (FI) of the initial operator is of a purely homological nature as it is based on the long exact connecting sequence provided by the so-called snake lemma in homological algebra. It is therefore quite difficult to grasp it in general and even more difficult to use it on explicit examples. It does not seem that any one of the results presented in this paper is known as most of the other authors who studied the above problem of computing the total number of generating CC are confusing this number with the degree of generality introduced by A. Einstein in his 1930 letters to E. Cartan. One of the motivating examples that we provide is so striking that it is even difficult to imagine that such an example could exist. We hope this paper could be used as a source of testing examples for future applications of computer algebra in general relativity and, more generally, in mathematical physics.
基金supported by the National Natural Science Foundation of China (61104180)the National Basic Research Program of China(973 Program) (97361361)
文摘Satellite observation scheduling plays a significant role in improving the efficiency of satellite observation systems.Although many scheduling algorithms have been proposed,emergency tasks,characterized as importance and urgency(e.g.,observation tasks orienting to the earthquake area and military conflict area),have not been taken into account yet.Therefore,it is crucial to investigate the satellite integrated scheduling methods,which focus on meeting the requirements of emergency tasks while maximizing the profit of common tasks.Firstly,a pretreatment approach is proposed,which eliminates conflicts among emergency tasks and allocates all tasks with a potential time-window to related orbits of satellites.Secondly,a mathematical model and an acyclic directed graph model are constructed.Thirdly,a hybrid ant colony optimization method mixed with iteration local search(ACO-ILS) is established to solve the problem.Moreover,to guarantee all solutions satisfying the emergency task requirement constraints,a constraint repair method is presented.Extensive experimental simulations show that the proposed integrated scheduling method is superior to two-phased scheduling methods,the performance of ACO-ILS is greatly improved in both evolution speed and solution quality by iteration local search,and ACO-ILS outperforms both genetic algorithm and simulated annealing algorithm.
基金the National Natural Science Foundation of China under Grant 61701059,Grant 61941114,and Grant 61831002,in part by the Fundamental Research Funds for the Central Universities of New TeachersProject,in part by the Chongqing Technological Innovation and Application Development Projects under Grant cstc2019jscx-msxm1322,and in part by the Eighteentg Open Foundation of State Key Lab of Integrated Services Networks of Xidian University under Grant ISN20-05.
文摘In the blockchain,the consensus mechanism plays a key role in maintaining the security and legitimation of contents recorded in the blocks.Various blockchain consensus mechanisms have been proposed.However,there is no technical analysis and comparison as a guideline to determine which type of consensus mechanism should be adopted in a specific scenario/application.To this end,this work investigates three mainstream consensus mechanisms in the blockchain,namely,Proof of Work(PoW),Proof of Stake(PoS),and Direct Acyclic Graph(DAG),and identifies their performances in terms of the average time to generate a new block,the confirmation delay,the Transaction Per Second(TPS)and the confirmation failure probability.The results show that the consensus process is affected by both network resource(computation power/coin age,buffer size)and network load conditions.In addition,it shows that PoW and PoS are more sensitive to the change of network resource while DAG is more sensitive to network load conditions.
基金the National Key R&D Program of China(No.2018YFC0310800)。
文摘A new acyclic peroxide derivative asperoxide A(1),along with 13 known compounds,namely,microperfuranone(2),9-hydroxymicroperfuranone(3),gibellulin A(4),lecanoric acid(5),terrequinone A(6),sterigmatocystin(7),isosecosterigmatocystin(8),arugosin C(9),curvularin(10),3,3'-diindolylmethane(11),austinol(12),austin(13),and dehydroaustin(14),were isolated and identified from the culture extract of Aspergillus nidulans SD-531,a fungus obtained from the deep-sea sediment of cold spring in the South China Sea.Their structures were determined based on detailed interpretation of nuclear magnetic resonance(NMR)spectroscopic and mass spectrometry data analysis.All the isolated compounds were evaluated for antimicrobial activities against human and aquatic bacteria as well as plant pathogenic fungi.Compounds 1–8,10,and 11 exhibited antimicrobial activities against some of the tested strains with minimum inhibitory concentration(MIC)values ranging from^2 to 64μg/mL.Compounds 4 and 6 displayed strongest activities among the tested samples and might be used as promising molecules for the development of natural antimicrobial agents.
文摘By employing a fixed point theorem due to Ding, Park and Jung, some existence theorems of solutions for equilibrium problems with lower and upper bounds are proved in noncompact topological spaces. These results further answer the open problem raised by Isac, Sehgal and Singh under much weaker assumptions.
基金supported by NSFC of China (No. 19871036 and No. 40301037)Faculty Research Grant,Hong Kong Baptist University
文摘A proper edge coloring of a graph G is called adjacent vertex-distinguishing acyclic edge coloring if there is no 2-colored cycle in G and the coloring set of edges incident with u is not equal to the coloring set of edges incident with v, where uv∈ E(G). The adjacent vertex distinguishing acyclic edge chromatic number of G, denoted by X'Aa(G), is the minimal number of colors in an adjacent vertex distinguishing acyclic edge coloring of G. If a graph G has an adjacent vertex distinguishing acyclic edge coloring, then G is called adjacent vertex distinguishing acyclic. In this paper, we obtain adjacent vertex-distinguishing acyclic edge coloring of some graphs and put forward some conjectures.
基金The National Natural Science Foundation of China(No.61741102,61471164,61601122)the Fundamental Research Funds for the Central Universities(No.SJLX_160040)
文摘In order to solve the problem of efficiently assigning tasks in an ad-hoc mobile cloud( AMC),a task assignment algorithm based on the heuristic algorithm is proposed. The proposed task assignment algorithm based on particle swarm optimization and simulated annealing( PSO-SA) transforms the dependencies between tasks into a directed acyclic graph( DAG) model. The number in each node represents the computation workload of each task and the number on each edge represents the workload produced by the transmission. In order to simulate the environment of task assignment in AMC,mathematical models are developed to describe the dependencies between tasks and the costs of each task are defined. PSO-SA is used to make the decision for task assignment and for minimizing the cost of all devices,which includes the energy consumption and time delay of all devices.PSO-SA also takes the advantage of both particle swarm optimization and simulated annealing by selecting an optimal solution with a certain probability to avoid falling into local optimal solution and to guarantee the convergence speed. The simulation results show that compared with other existing algorithms,the PSO-SA has a smaller cost and the result of PSO-SA can be very close to the optimal solution.
文摘Some new coincidence theorems involving a new class of set-valued mappingscontaining composites of acyclic mappings defined on a contractible space are proved.As applications, some existence theorems of maximal elements and solutions of abstract variational inequalities, and best approximation theorems are proved. These theorems improve and generalize a number of known results in recent literature.
文摘Two new isomeric compounds of rare acyclic C13-norisoprenoids, along with two known lignans sauchinone and licarin A, were isolated from the herb of Saururus chinensis (Lour.) Baill. Their structures were elucidated on the basis of spectral analysis.
基金the Scientific Technology Development Project of Heilongjiang(Grant No.WH05A01 and GB05A103)Scientific Technology Development Project of Harbin
文摘Based on the key function of version management in PDM system, this paper discusses the function and the realization of version management and the transitions of version states with a workflow. A directed aeyclic graph is used to describe a version model. Three storage modes of the directed acyelic graph version model in the database, the bumping block and the PDM working memory are presented and the conversion principle of these three modes is given. The study indicates that building a dynamic product structure configuration model based on versions is the key to resolve the problem. Thus a version model of single product object is built. Then the version management model in product structure configuration is built and the application of version management of PDM syster is presented as a case.
文摘Eight novel heterobinuclear complexes of Ln3+ and Zn2+ with salicylidene diethylene glycol diamine(SALDA) Schiff base (NO3)22H2O(Ln=Pr, Nd, Sm, Gd, Tb, Er, Yb, Y) were synthesized and characterized on the basis of IR and UV, particularly by1H and13C NMR spectra. It is confirmed that the azomethine nitrogen, ethereal oxygen and a part of phenolic oxygen atoms coordinate to the central ions.
文摘A series of novel L-amino acid esters prodrugs of acyclic nucleoside phosphonates was synthesized and their anti-HBV activity was evaluated in HepG2 2.2.15 cells. Compound 1d exhibited more potent anti-HBV activity and lower cytotoxicity than those of adefovir dipivoxil with EC50 and CC50 values of 0.207 μmol/L and 2530 μmol/L, respectively.
基金Projects(70631002,70701027) supported by the National Natural Science Foundation of ChinaProject(NCET-08-0406) supported by the Program for New Century Excellent Talents in Chinese University
文摘Key tactics of origin-based user equilibrium (OUE) algorithm was studied,which involved the algorithm procedure and several implementation issues.To speed up the convergence,update policies of flows,costs and bushes were proposed.The methods of step-size searching and bush construction are proved to be practical.The modified OUE algorithm procedure was also optimized to take the advantage of multi-thread process.Convergence performances were compared with those of other algorithms by different sizes of urban transportation networks.The result shows this modified OUE algorithm is more efficient and consumes less time to achieve the reasonable relative gap in practical applications.
基金Sponsored by the National Natural Science Foundation of China(Grant No.61201310)the Fundamental Research Funds for the Central Universities(Grant No.HIT.NSRIF.201160)the China Postdoctoral Science Foundation(Grant No.20110491067)
文摘Based on the framework of support vector machines (SVM) using one-against-one (OAO) strategy, a new multi-class kernel method based on directed aeyclie graph (DAG) and probabilistic distance is proposed to raise the multi-class classification accuracies. The topology structure of DAG is constructed by rearranging the nodes' sequence in the graph. DAG is equivalent to guided operating SVM on a list, and the classification performance depends on the nodes' sequence in the graph. Jeffries-Matusita distance (JMD) is introduced to estimate the separability of each class, and the implementation list is initialized with all classes organized according to certain sequence in the list. To testify the effectiveness of the proposed method, numerical analysis is conducted on UCI data and hyperspectral data. Meanwhile, comparative studies using standard OAO and DAG classification methods are also conducted and the results illustrate better performance and higher accuracy of the orooosed JMD-DAG method.
文摘A new static task scheduling algorithm named edge-zeroing based on dynamic critical paths is proposed. The main ideas of the algorithm are as follows: firstly suppose that all of the tasks are in different clusters; secondly, select one of the critical paths of the partially clustered directed acyclic graph; thirdly, try to zero one of graph communication edges; fourthly, repeat above three processes until all edges are zeroed; finally, check the generated clusters to see if some of them can be further merged without increasing the parallel time. Comparisons of the previous algorithms with edge-zeroing based on dynamic critical paths show that the new algorithm has not only a low complexity but also a desired performance comparable or even better on average to much higher complexity heuristic algorithms.
文摘Topomer CoMFA models have been used to optimize the potency of 15 biologically active acridone derivatives se- lected from the literature. Their 3D chemical structures were sliced into three acyclic R groups, to produce a fragment that is present in each training set. The analysis was successful with 3 as the number of components that provided the highest q2 results: q2 is 0.56, which is the cross-validated coefficient for the specified number of components, giving rise to 0.37 standard error of estimate (q2 stderr), and a conventional coefficient (r2) of 0.82, whose standard error of estimate is 0.24. These results provide structure-activity relationship (sar) among the compounds. The result of the To-pomer CoMFA studies was used to design novel derivatives for future studies.
文摘A proper edge colouring f of a graph G is called acyclic if there are no bichromatic cycles in the graph. The acyclic edge chromatic number or acyclic chromatic index, denoted by , is the minimum number of colours in an acyclic edge colouring of G. In this paper, we discuss the acyclic edge colouring of middle, central, total and line graphs of prime related star graph families. Also exact values of acyclic chromatic indices of such graphs are derived and some of their structural properties are discussed.