AIM:To measure the central choroidal thickness(ChT)in children and adolescents with anxiety disorders.METHODS:Totally 41 anxiety patients(8-16 y)and 35 healthy controls(age-matched)were evaluated.Complete ophthalmic e...AIM:To measure the central choroidal thickness(ChT)in children and adolescents with anxiety disorders.METHODS:Totally 41 anxiety patients(8-16 y)and 35 healthy controls(age-matched)were evaluated.Complete ophthalmic examination was performed.Inclusion criteria were best corrected visual acuity≥20/20,normal intraocular pressure(IOP;10-21 mm Hg),and no systemic or ocular diseases according to history.The diagnosis of psychiatric disorders was determined using Schedule for Affective Disorders and Schizophrenia for School Aged Children Present-Lifetime Version(K-SADS-PL).Enhanced depth imaging optical coherence tomography(EDI-OCT)was used to measure the central ChT.RESULTS:The mean age was 12.18±3.24 y in the patient group and 12.86±3.15 y in the control group.Age and gender distribution of the two groups was similar.Central ChT mean value was 353.26±31.9μm in anxiety patients while 318.75±60.9μm in the control group.Mean central ChT was statistically significantly higher in the children and adolescents with anxiety disorders than healthy controls(P=0.002).CONCLUSION:The children and adolescents with anxiety disorders have significantly thicker central ChT than controls.In the larger sample,longitudinal studies will contribute to the use of choroidal differences as a clinical marker for monitoring anxiety disorders.展开更多
目的：探讨少年焦虑障碍的家庭动力学特征。方法：采用方便取样，选取焦虑障碍患者110例（年龄≤18岁），同时，以地区、性别、年龄相匹配选取正常学生149例。用家庭亲密度及适应性量表（Family Adaptability and Cohesion Scale second...目的：探讨少年焦虑障碍的家庭动力学特征。方法：采用方便取样，选取焦虑障碍患者110例（年龄≤18岁），同时，以地区、性别、年龄相匹配选取正常学生149例。用家庭亲密度及适应性量表（Family Adaptability and Cohesion Scale second edition，FACES—CV）、系统家庭动力学自评量表（Self rating Scale of Systemic Family Dynamics，SSFD）及一般人口学调查表进行调查。结果：病例组FACES—CV的家庭亲密度得分低于对照组，而SSFD的家庭气氛、系统逻辑和疾病观念得分高于对照组（均P〈0．05）。Logistic回归分析显示，好的家庭经济状况（OR=0．74，95％CI：0．59～0．96）、高家庭亲密度（OR=0．96，95％CI：0．94—0．99）是少年焦虑障碍的保护性因素，而高疾病观念（OR=1．18；95％CI：1．01—1．21）是危险性因素。结论：焦虑障碍少年具有不同于非焦虑障碍少年的家庭动力特征，家庭情感的联结程度及成员针对自我责任的不同的家庭观念与少年焦虑障碍相关。展开更多
文摘AIM:To measure the central choroidal thickness(ChT)in children and adolescents with anxiety disorders.METHODS:Totally 41 anxiety patients(8-16 y)and 35 healthy controls(age-matched)were evaluated.Complete ophthalmic examination was performed.Inclusion criteria were best corrected visual acuity≥20/20,normal intraocular pressure(IOP;10-21 mm Hg),and no systemic or ocular diseases according to history.The diagnosis of psychiatric disorders was determined using Schedule for Affective Disorders and Schizophrenia for School Aged Children Present-Lifetime Version(K-SADS-PL).Enhanced depth imaging optical coherence tomography(EDI-OCT)was used to measure the central ChT.RESULTS:The mean age was 12.18±3.24 y in the patient group and 12.86±3.15 y in the control group.Age and gender distribution of the two groups was similar.Central ChT mean value was 353.26±31.9μm in anxiety patients while 318.75±60.9μm in the control group.Mean central ChT was statistically significantly higher in the children and adolescents with anxiety disorders than healthy controls(P=0.002).CONCLUSION:The children and adolescents with anxiety disorders have significantly thicker central ChT than controls.In the larger sample,longitudinal studies will contribute to the use of choroidal differences as a clinical marker for monitoring anxiety disorders.
文摘目的：探讨少年焦虑障碍的家庭动力学特征。方法：采用方便取样，选取焦虑障碍患者110例（年龄≤18岁），同时，以地区、性别、年龄相匹配选取正常学生149例。用家庭亲密度及适应性量表（Family Adaptability and Cohesion Scale second edition，FACES—CV）、系统家庭动力学自评量表（Self rating Scale of Systemic Family Dynamics，SSFD）及一般人口学调查表进行调查。结果：病例组FACES—CV的家庭亲密度得分低于对照组，而SSFD的家庭气氛、系统逻辑和疾病观念得分高于对照组（均P〈0．05）。Logistic回归分析显示，好的家庭经济状况（OR=0．74，95％CI：0．59～0．96）、高家庭亲密度（OR=0．96，95％CI：0．94—0．99）是少年焦虑障碍的保护性因素，而高疾病观念（OR=1．18；95％CI：1．01—1．21）是危险性因素。结论：焦虑障碍少年具有不同于非焦虑障碍少年的家庭动力特征，家庭情感的联结程度及成员针对自我责任的不同的家庭观念与少年焦虑障碍相关。
