目的探讨益气消癥汤治疗晚期非小细胞肺癌(Non-small-cell carcinoma,NSCLC)合并慢性阻塞性肺疾病(Chronic obstructive pulmonary disease,COPD)的临床疗效。方法选择新疆医科大学第四临床医学院2022年3月至2023年1月的130例晚期NSCLC...目的探讨益气消癥汤治疗晚期非小细胞肺癌(Non-small-cell carcinoma,NSCLC)合并慢性阻塞性肺疾病(Chronic obstructive pulmonary disease,COPD)的临床疗效。方法选择新疆医科大学第四临床医学院2022年3月至2023年1月的130例晚期NSCLC合并COPD患者,按随机数字表法分为对照组和观察组,各65例。对照组接受常规治疗,观察组在对照组常规治疗基础上加用益气消癥汤治疗,比较两组患者治疗前后肺功能水平、治疗效果、免疫功能以及不良反应。结果治疗3个月后,观察组患者一氧化碳弥散量(Diffusing capacity of the lungs for carbon monoxide,DLCO)、第一秒用力呼气容积(Forced expiratory volume in one second,FEV1)、FEV1/用力肺活量(Forced vital capacity,FVC)等肺功能指标均较对照组提高(P<0.05),且总体有效率高于对照组,差异有统计学意义(P<0.05)。观察组的免疫球蛋白含量和T细胞亚群水平均高于对照组(P<0.05),不良反应发生率低于对照组(P<0.05)。结论益气消癥汤在改善晚期NSCLC合并COPD患者肺功能、提升治疗效果、增强免疫功能方面优势明显,且不良反应小,临床应用安全可靠。展开更多
Objective： This review aimed to examine the effectiveness of clinical nurse specialist （CNS） interventions in patients with chronic obstructive pulmonary disease （COPD）. COPD significantly affects p...Objective： This review aimed to examine the effectiveness of clinical nurse specialist （CNS） interventions in patients with chronic obstructive pulmonary disease （COPD）. COPD significantly affects people＇s health worldwide. With the development in nursing, CNSs are playing increasingly important roles in different departments. However, the studies on the effectiveness of CNSs in COPD are not as well organized as the studies on the effectiveness of CNSs in bronchiectasis and asthma. Therefore, this review aims to find some updated evidence on the CNS interventions for patients with COPD and on whether these interventions are effective.Methods： A narrative analysis of the data was performed for the eligible studies. Four databases were chosen： CINAHL, MEDLINE, British Nursing Index, and Cochrane Library. Other websites such as the National Institute for Health and Clinical Excellence, National Health Service Evidence, Association of Respiratory Nurse Specialists, and National Association of Clinical Nurse Specialist were searched as well. Two reviewers performed study identification independently, and all the retrieved articles were stored using the EndNote X7 software. The risk of bias in the included studies was assessed using the Cochrane Collaboration＇s risk of bias tool. Results： A total of nine studies were included in this review. There were five current interventions by CNSs for patients with COPD. These interventions were home nursing support, CNS]s supported discharge, multidisciplinary cooperation programs, nurse-led care programs, and self-care management education. The effectiveness of these five interventions was evaluated individually. There is low- to moderate-quality evidence indicating that home nursing support interventions may have a positive effect on mortality and quality of life. No significant difference in quality of life has been found between the CNS-supported discharge intervention and the usual service. The multidisciplinary cooperation program probably had a positive effect on quality ot life in patients with COPD. Both nurse-led care and self-care management education intervention had a positive effect on mortality of patients with COPD.Conclusions： The findings of this review provide updated evidence on the effectiveness of CNS interventions for patients with COPD. Although nine trials were included and five types of interventions were identified, there is still lack of high-quality evidence.展开更多
The advances in the treatment of heart failure with Yangxinshi tablet are reviewed in this paper.Yangxinshi tablet has effects of nourishing myocardia,improving myocardial metabolism,reducing myocardial oxygen consump...The advances in the treatment of heart failure with Yangxinshi tablet are reviewed in this paper.Yangxinshi tablet has effects of nourishing myocardia,improving myocardial metabolism,reducing myocardial oxygen consumption,dilating coronary artery,improving cardiac blood supply,reducing blood viscosity and improving microcirculation,and it can improve the functions of heart and curative effect of heart failure.展开更多
Chronic obstructive pulmonary disease （COPD） is a leading cause of morbidity and mortality worldwide and results in an economic and social burden that is both substantial and increasing. By the year 2020, COPD will ...Chronic obstructive pulmonary disease （COPD） is a leading cause of morbidity and mortality worldwide and results in an economic and social burden that is both substantial and increasing. By the year 2020, COPD will be the third leading cause of mortality and the fifth leading cause of disability worldwide, In a population based study conducted at multiple international sites, approximately 10% of participants 40 years of age or older were found to have airflow obstruction of at least moderate severity according to spirometric criteria. In China, the overall prevalence of COPD in individuals 40 years of age or older was 8.2%.m COPD is a slowly progressive respiratory disease, which, although preventable and treatable, is not curable. The final years for patients with advanced COPD are characterized by progressive functional decline, frequent exacerbations, poor quality of life, increasing dependency on informal caregivers and on the health care system. According to the literature, 5-year survival from diagnosis is estimated to be 78% in men and 72% in women with mild disease, but only 30% in men and 24% in women with advanced COPD.展开更多
文摘目的探讨益气消癥汤治疗晚期非小细胞肺癌(Non-small-cell carcinoma,NSCLC)合并慢性阻塞性肺疾病(Chronic obstructive pulmonary disease,COPD)的临床疗效。方法选择新疆医科大学第四临床医学院2022年3月至2023年1月的130例晚期NSCLC合并COPD患者,按随机数字表法分为对照组和观察组,各65例。对照组接受常规治疗,观察组在对照组常规治疗基础上加用益气消癥汤治疗,比较两组患者治疗前后肺功能水平、治疗效果、免疫功能以及不良反应。结果治疗3个月后,观察组患者一氧化碳弥散量(Diffusing capacity of the lungs for carbon monoxide,DLCO)、第一秒用力呼气容积(Forced expiratory volume in one second,FEV1)、FEV1/用力肺活量(Forced vital capacity,FVC)等肺功能指标均较对照组提高(P<0.05),且总体有效率高于对照组,差异有统计学意义(P<0.05)。观察组的免疫球蛋白含量和T细胞亚群水平均高于对照组(P<0.05),不良反应发生率低于对照组(P<0.05)。结论益气消癥汤在改善晚期NSCLC合并COPD患者肺功能、提升治疗效果、增强免疫功能方面优势明显,且不良反应小,临床应用安全可靠。
文摘Objective： This review aimed to examine the effectiveness of clinical nurse specialist （CNS） interventions in patients with chronic obstructive pulmonary disease （COPD）. COPD significantly affects people＇s health worldwide. With the development in nursing, CNSs are playing increasingly important roles in different departments. However, the studies on the effectiveness of CNSs in COPD are not as well organized as the studies on the effectiveness of CNSs in bronchiectasis and asthma. Therefore, this review aims to find some updated evidence on the CNS interventions for patients with COPD and on whether these interventions are effective.Methods： A narrative analysis of the data was performed for the eligible studies. Four databases were chosen： CINAHL, MEDLINE, British Nursing Index, and Cochrane Library. Other websites such as the National Institute for Health and Clinical Excellence, National Health Service Evidence, Association of Respiratory Nurse Specialists, and National Association of Clinical Nurse Specialist were searched as well. Two reviewers performed study identification independently, and all the retrieved articles were stored using the EndNote X7 software. The risk of bias in the included studies was assessed using the Cochrane Collaboration＇s risk of bias tool. Results： A total of nine studies were included in this review. There were five current interventions by CNSs for patients with COPD. These interventions were home nursing support, CNS]s supported discharge, multidisciplinary cooperation programs, nurse-led care programs, and self-care management education. The effectiveness of these five interventions was evaluated individually. There is low- to moderate-quality evidence indicating that home nursing support interventions may have a positive effect on mortality and quality of life. No significant difference in quality of life has been found between the CNS-supported discharge intervention and the usual service. The multidisciplinary cooperation program probably had a positive effect on quality ot life in patients with COPD. Both nurse-led care and self-care management education intervention had a positive effect on mortality of patients with COPD.Conclusions： The findings of this review provide updated evidence on the effectiveness of CNS interventions for patients with COPD. Although nine trials were included and five types of interventions were identified, there is still lack of high-quality evidence.
文摘The advances in the treatment of heart failure with Yangxinshi tablet are reviewed in this paper.Yangxinshi tablet has effects of nourishing myocardia,improving myocardial metabolism,reducing myocardial oxygen consumption,dilating coronary artery,improving cardiac blood supply,reducing blood viscosity and improving microcirculation,and it can improve the functions of heart and curative effect of heart failure.
文摘Chronic obstructive pulmonary disease （COPD） is a leading cause of morbidity and mortality worldwide and results in an economic and social burden that is both substantial and increasing. By the year 2020, COPD will be the third leading cause of mortality and the fifth leading cause of disability worldwide, In a population based study conducted at multiple international sites, approximately 10% of participants 40 years of age or older were found to have airflow obstruction of at least moderate severity according to spirometric criteria. In China, the overall prevalence of COPD in individuals 40 years of age or older was 8.2%.m COPD is a slowly progressive respiratory disease, which, although preventable and treatable, is not curable. The final years for patients with advanced COPD are characterized by progressive functional decline, frequent exacerbations, poor quality of life, increasing dependency on informal caregivers and on the health care system. According to the literature, 5-year survival from diagnosis is estimated to be 78% in men and 72% in women with mild disease, but only 30% in men and 24% in women with advanced COPD.
