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Advanced treatment of biologically pretreated coking wastewater by intensified zero-valent iron process(IZVI) combined with anaerobic filter and biological aerated filter(AF/BAF) 被引量:4
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作者 潘碌亭 韩悦 吴锦峰 《Journal of Central South University》 SCIE EI CAS CSCD 2015年第10期3781-3787,共7页
Experiments were conducted to investigate the behavior of the sequential system of intensified zero-valent iron process(IZVI) and anaerobic filter and biological aerated filter(AF/BAF) reactors for advanced treatment ... Experiments were conducted to investigate the behavior of the sequential system of intensified zero-valent iron process(IZVI) and anaerobic filter and biological aerated filter(AF/BAF) reactors for advanced treatment of biologically pretreated coking wastewater. Particular attention was paid to the performance of the integrated system for the removal of chemical oxygen demand(COD), ammonia nitrogen(NH3-N) and total nitrogen(TN). The average removal efficiencies of COD, NH3-N and TN were 76.28%, 96.76% and 59.97%, with the average effluent mass concentrations of 56, 0.53 and 18.83 mg/L, respectively, reaching the first grade of the national discharge standard. Moreover, the results of gas chromatography/mass spectrum(GC/MS) and gel permeation chromatography(GPC) analysis demonstrated that the refractory organic compounds with high relative molecular mass were partly removed in IZVI process by the function of oxidation-reduction, flocculation and adsorption which could also enhance the biodegradability of the system effluent. The removal efficiencies of NH3-N and TN were achieved mainly in the subsequent AF/BAF reactors by nitrification and denitrification. Overall, the results obtained show that the application of IZVI in combination with AF/BAF is a promising technology for advanced treatment of biologically pretreated coking wastewater. 展开更多
关键词 advanced treatment coking wastewater intensified zero valent iron BIOFILTER
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Enriched Oxygen BAC Method in Advanced Treatment of Textile Dyeing-printing & Alkali-peeling Wastewater 被引量:1
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作者 田晴 陈季华 张华 《Journal of Donghua University(English Edition)》 EI CAS 2006年第1期84-88,共5页
A novel Pressurized Enriched Oxygen Biological Activated Carbon (PRBAC) method in treating secondary effluent of textile dying-printing & alkali peeling wastewater was configured. The PRBAC reactor simply increased... A novel Pressurized Enriched Oxygen Biological Activated Carbon (PRBAC) method in treating secondary effluent of textile dying-printing & alkali peeling wastewater was configured. The PRBAC reactor simply increased reactor pressure to create an eurtched dissolved oxygen (DO) environment to stimulate the bioactivities of microbes on GAC surface for removing refractory organic matter. Rapid Small- Scaled Colunm Test (RSSCT) was carried out to evaluate the adsorption characteristics of target stream constituents, and over 80% COD components were poorly adsorbable while about 82.5% color inducing matter and 85% UV254 surrogated matter were readily adsorbable. Compared with performances of normal BAC reactor under conventional DO condition, PRBAC achieved 20%, 10% and 50% more removal in COD, color and NH3-N abatement. 展开更多
关键词 PRBAC method textile dying-printing alkali-peeling wastewter enriched oxygen condition advanced treatment RSSCT
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Pilot Study on Drinking Water Advanced Treatment by GAC-MF System 被引量:1
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作者 王欣泽 薛罡 +1 位作者 王宝贞 王琳 《Journal of Donghua University(English Edition)》 EI CAS 2004年第1期135-139,共5页
The pilot performance of the combined GAC-MF membrane process for drinking water advanced treatment was described. In the process of GAC adsorption, under the conditions of 20 min HRT and 6 m/h filtration rate, the re... The pilot performance of the combined GAC-MF membrane process for drinking water advanced treatment was described. In the process of GAC adsorption, under the conditions of 20 min HRT and 6 m/h filtration rate, the removal efficiencies of UV_(254) and trichloromethane could reach 40% and 50% respectively and the UV_(254) and trichloromethane in system effluent was less than 0.015 cm^(-1) and 5μg/L respectively. In the post MF membrane process, MF membrane effectively retained the particles and bacteria in raw water. The effluent turbidity was less than 0.2 NTU and no bacteria were detected at all in permeate. A computer-controlled system was employed to control this system. The membrane operating parameters of backwash interval, duration and flux were studied. The backwash interval of 10-min, 20-min and 60-min was researched respectively, and the variation of trans-membrane pressure was also analyzed. Consequently short backwash interval was recommended under the same water consume. 展开更多
关键词 granular activated carbon adsorption MF membrane drinking water advanced treatment
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Advanced Treatment of Biologically Treated Chemical Comprehensive Wastewater by Nano-TiO2 Photocatalytic Oxidation
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作者 Zhai Jian Jiang Chunhua Chen Feng 《Meteorological and Environmental Research》 CAS 2018年第3期105-108,共4页
Nano-TiO2 photocatalytic oxidation was used to perform the advanced treatment of biologically treated chemical comprehensive wastewater. The effects of reaction time,nano-TiO2 dosage and initial p H of the wastewater ... Nano-TiO2 photocatalytic oxidation was used to perform the advanced treatment of biologically treated chemical comprehensive wastewater. The effects of reaction time,nano-TiO2 dosage and initial p H of the wastewater on the removal rate of COD were tested. The GC/MS and EEM techniques were used to qualitatively analyze organic compounds in the wastewater before and after treatment. The result showed that after the biologically treated chemical comprehensive wastewater was treated by nano-TiO2 photocatalytic oxidation under the conditions of reaction time 3 h,nano-TiO2 dosage 8 g/L,and pH 8. 0,the effluent COD was 61. 9 mg/L and its removal rate was 63. 8%. Additionally,the species of organic pollutants reduced from 12 to 6. Meanwhile,the content of humic-like and fulvic-like substances dropped dramatically. 展开更多
关键词 Biologically treated chemical comprehensive wastewater NANO-TIO2 Photocatalytic oxidation technology advanced treatment GC-MS EEM
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Monitoring of 943 organic micropollutants in wastewater from municipal wastewater treatment plants with secondary and advanced treatment processes 被引量:10
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作者 Juan Wang Zhe Tian +3 位作者 Yingbin Huo Min Yang Xingcan Zheng Yu Zhang 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2018年第5期309-317,共9页
To perform a systematic survey on the occurrence and removal of micropollutants during municipal wastewater treatment, 943 semi-volatile organic chemicals in 32 wastewater samples including influents of secondary trea... To perform a systematic survey on the occurrence and removal of micropollutants during municipal wastewater treatment, 943 semi-volatile organic chemicals in 32 wastewater samples including influents of secondary treatments, secondary effluents and final effluents(effluents of advanced treatments), which were collected from seven full-scale municipal wastewater treatment plants(MWTPs) in China, were examined by gas chromatography-mass spectrometry(GC-MS) coupled with an automated identification and quantification system with a database(AIQS-DB). In total, 196 and 145 chemicals were detected in secondary and final effluents, respectively. The majority of the total concentrations(average removal efficiency, 87.0%±5.9%) of the micropollutants were removed during secondary treatments. However, advanced treatments achieved different micropollutant removal extents from secondary effluents depending on the different treatment processes employed. Highly variable removal efficiencies of total concentrations(32.7%–99.3%) were observed among the different advanced processes. Among them,ozonation-based processes could remove 70.0%–80.9% of the total concentrations of studied micropollutants. The potentially harmful micropollutants, based on their detection frequency and concentration in secondary and final effluents, were polycyclic aromatic hydrocarbons(PAHs)(2-methylnaphthalene, fluoranthene, pyrene, naphthalene and phenanthrene), phosphorus flame retardants(tributyl phosphate(TBP), tris(2-chloroethyl)phosphate(TCEP) and tris(1,3-dichloro-2-propyl) phosphate(TDCP)), phthalates(bis(2-ethylhexyl)phthalate(DEHP)), benzothiazoles(benzothiazole,2-(methylthio)-benzothiazol, and 2(3H)-benzothiazolone) and phenol. This study indicated that the presence of considerable amounts of micropollutants in secondary effluent creates the need for suitable advanced treatment before their reuse. 展开更多
关键词 Automated identification andquantification system Municipal wastewater treatment Organic micropollutants Secondary treatment advanced treatment
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Anaerobic ammonium oxidation for advanced municipal wastewater treatment: is it feasible? 被引量:8
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作者 LI Jie XIONG Bi-yong +2 位作者 ZHANG Shu-de YANG Hong ZHANG Jie 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2005年第6期1022-1024,共3页
Anaerobic ammonium oxidation(ANAMMOX) is a recently developed process to treat ammonia-rich wastewater. There were numerous articles about the new technology with focus on the ammonium-rich wastewater treatment, but... Anaerobic ammonium oxidation(ANAMMOX) is a recently developed process to treat ammonia-rich wastewater. There were numerous articles about the new technology with focus on the ammonium-rich wastewater treatment, but few on advanced municipal wastewater treatment. The paper studied the anaerobic ammonium oxidation (ANAMMOX) process with a down flow anoxic biofilter for nitrogen removal from secondary clarifier effluent of municipal wastewater with low COD/N ratio. The results showed that ANAMMOX process is applicable to advanced wastewater treatment with normal temperature as well as ammonia-rich high temperature wastewater treatment. The results indicated that ammonia removal rate was improved by raising the nitrite concentration, and the reaction rate reached a climax at 118.4 mgN/L of the nitrite nitrogen concentration. If the concentration exceeds 118.4 mgN/L, the ANAMMOX process was significantly inhibited although the ANAMMOX bacteria still showed a relatively high reactivity. The data also indicated that the ratio of NO2^- -N:NH4 * -N = 1.3:1 in the influent was appropriate for excellent nitrogen removal. The pH increased gradually along the ANAMMOX biofilter reactor. When the ANAMMOX reaction was ended, the pH was tend to calm. The data suggested that the pH could be used as an indicator to describe the course of ANAMMOX reaction. 展开更多
关键词 ANAMMOX anoxic biofilter advanced treatment nitrogen removal NITRITE
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Advanced treatment of wet-spun acrylic fiber manufacturing wastewater using three-dimensional electrochemical oxidation 被引量:8
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作者 Tianlong Zheng, Qunhui Wang +4 位作者 Zhining Shi Yue Fang Shanshan Shi Juan Wang Chuanfu Wu 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2016年第12期21-31,共11页
A three-dimensional electrochemical oxidation (3D-EC) reactor with introduction of activated carbon (AC) as particle micro-electrodes was apphed for the advanced treatment of secondary wastewater effluent of a wet... A three-dimensional electrochemical oxidation (3D-EC) reactor with introduction of activated carbon (AC) as particle micro-electrodes was apphed for the advanced treatment of secondary wastewater effluent of a wet-spun acrylic fiber manufacturing plant. Under the optimized conditions (current density of 500 A/m2, circulation rate of 5 mL/min, AC dosage of 50 g, and chloride concentration of 1.0 g/L), the average removal efficiencies of chemical oxygen demand (CODer), NH3-N, total organic carbon (TOC), and ultraviolet absorption at 254 nm (UV2s4) of the 3D-EC reactor were 64.5%, 60.8%, 46.4%, and 64.8%, respectively; while the corresponding effluent concentrations of CODcr, NH3-N, TOC, and UV2s4 were 76.6, 20.1, and 42.5 mg/L, and 0.08 Abs/cm, respectively. The effluent concentration of CODer was less than 100 mg/L, which showed that the treated wastewater satisfied the demand of the integrated wastewater discharge standard (GB 8978-1996). The 3D-EC process remarkably improved the treatment efficiencies with synergistic effects for CODer, NH3-N, TOC, and UV2s4 during the stable stage of 44.5%, 38.8%, 27.2%, and 10.9%, respectively, as compared with the sum of the efficiencies of a two-dimensional electrochemical oxidation (2D-EC) reactor and an AC adsorption process, which was ascribed to the numerous micro-electrodes of AC in the 3D-EC reactor. Gas chromatography mass spectrometry (GC-MS) analysis revealed that electro- chemical treatment did not generate more toxic organics, and it was proved that the increase in acute biotoxicity was caused primarily by the production of free chlorine. 展开更多
关键词 advanced treatment Synergistic effect Three-dimensional electrochemicaloxidation Wet-spun acrylic fiber wastewater
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Sonication for advanced drinking water treatment 被引量:1
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作者 张光明 魏希柱 +2 位作者 李相昆 张杰 豆子波 《Journal of Harbin Institute of Technology(New Series)》 EI CAS 2009年第1期16-20,共5页
This paper investigated the feasibility of sonication as an advanced treatment method for drinking water production and used comprehensive indexes of water quality to examine its efficiency. Results show that sonicati... This paper investigated the feasibility of sonication as an advanced treatment method for drinking water production and used comprehensive indexes of water quality to examine its efficiency. Results show that sonication significantly reduces the toxicity of water. Sonication with 5 W/L at 90 kHz lasting for 30 rain decreases the water SUVA and the disinfection byproduct formation potential (DBPFP) by 38.7% and 27. 2% respectively. Sonication also decreases the UV254 by more than 50% through destroying unsaturated chemical bonds. Higher sound intensity and higher frequency benefit the reduction of TOC and UV254. Besides, sonication significantly increases the affinity of organics with granular activated carbon ( GAC ) , and thus the hybrid sonication-GAC method reduces the water TOC, COD, UV254, and DBPFP by 78.3%, 69.4%, 75.7%, and 70.0% respectively. Therefore, sonication and the hybrid sonication-GAC metbod are proposed as advanced treatment methods for drinking water. 展开更多
关键词 sonieation drinking water advanced treatment DBPFP
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Dual stimuli-responsive polyurethane-based hydrogels as smart drug delivery carriers for the advanced treatment of chronic skin wounds 被引量:5
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作者 Rossella Laurano Monica Boffito +4 位作者 Michela Abrami Mario Grassi Alice Zoso Valeria Chiono Gianluca Ciardelli 《Bioactive Materials》 SCIE 2021年第9期3013-3024,共12页
The design of multi-stimuli-responsive vehicles for the controlled and localized release of drugs is a challenging issue increasingly catching the attention of many research groups working on the advanced treatment of... The design of multi-stimuli-responsive vehicles for the controlled and localized release of drugs is a challenging issue increasingly catching the attention of many research groups working on the advanced treatment of hard-to-close wounds.In this work,a thermo-and pH-responsive hydrogel(P-CHP407)was prepared from an ad hoc synthesized amphiphilic poly(ether urethane)(CHP407)exposing a significant amount of-COOH groups(8.8±0.9 nmol/g_(polymer)).The exposure of acid moieties in P-CHP407 hydrogel led to slightly lower initial gelation temperature(12.1◦C vs.14.6◦C,respectively)and gelation rate than CHP407 hydrogel,as rheologically assessed.Nanoscale hydrogel characterization by Low Field NMR(LF-NMR)spectroscopy suggested that the presence of carboxylic groups in P-CHP407 caused the formation of bigger micelles with a thicker hydrated shell than CHP407 hydrogels,as further proved by Dynamic Light Scattering analyses.In addition,P-CHP407 hydrogel showed improved capability to change its internal pH compared to CHP407 one when incubated with an alkaline buffer(pH 8)(e.g.,pH_(change_5min)=3.76 and 1.32,respectively).Moreover,LF-NMR characterization suggested a stronger alkaline-pH-induced interaction of water molecules with micelles exposing-COOH groups.Lastly,the hydrogels were found biocompatible according to ISO 10993 and able to load and release Ibuprofen:delivery kinetics of Ibuprofen was enhanced by P-CHP407 hydrogels at alkaline pH,suggesting their potential use as smart delivery systems in the treatment of chronic infected wounds. 展开更多
关键词 Stimuli-responsive hydrogel Drug delivery system pH-triggered release advanced wound treatment Polyurethane hydrogel LF-NMR characterization
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Immobilization biological activated carbon used in advanced drinking water treatment 被引量:2
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作者 马放 杨海燕 王弘宇 《Journal of Harbin Institute of Technology(New Series)》 EI CAS 2006年第6期678-682,共5页
Bacteria separated from a mature filter bed of groundwater treatment plants were incubated in a culture media containing iron and manganese. A consortium of 5 strains of bacteria removing iron and manganese were obtai... Bacteria separated from a mature filter bed of groundwater treatment plants were incubated in a culture media containing iron and manganese. A consortium of 5 strains of bacteria removing iron and manganese were obtained by repeated enrichment culturing. It was shown from the experiments of effect factors that ironmanganese removal bacteria in the euhure media containing both Fe and Mn grew better than in that containing only Fe, however, they were unable to grow in the culture media containing only Mn. When comparing the bacteria biomass in the case ofp (DO) :2.8 mg/L andp (DO) :9. 0 mg/L, no significant difference was found. The engineering bacteria removing the organic and the bacteria removing iron and manganese were simuhaneously inoculated into activated carbon reactor to treat the effluent of distribution network. The experimental results showed that by using IBAC ( Immobilization Biological Activated Carbon) treatment, the removal efficiency of iron, manganese and permanganate index was more than 98% , 96% and 55% , respectively. After the influent with turbidity of 1.5 NTU, color of 25 degree and oflbnsive odor was treated, the turbidity and color of effluence were less than 0.5 NTU and 15 degree, respectively, and it was odorless. It is determined that the cooperation function of engineering bacteria and activated carbon achieved advanced drinking water treatment. 展开更多
关键词 advanced drinking water treatment miero-pollutaats IBAC: iron and manganese removal engi- neering bacteria
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Improving AOC degradation rate by intensified biological process in advanced water treatment 被引量:1
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作者 安东 李伟光 +1 位作者 宋佳秀 崔福义 《Journal of Harbin Institute of Technology(New Series)》 EI CAS 2007年第1期93-96,共4页
The object of is to evaluate assimilable organic carbon(AOC) degradation rate by intensified biological technique in advanced water treatment. By artificially acclimating and cultivating strains attached onto carbon... The object of is to evaluate assimilable organic carbon(AOC) degradation rate by intensified biological technique in advanced water treatment. By artificially acclimating and cultivating strains attached onto carbon surface, the selected strains can be intensified for their degradation to organic matters. The research indicates that ozonation process increases AOC concentration considerably, however, it is beneficial to microdegradation. Temperature and empty bed contact time ( TEBC ) are two important factors affecting microbiology. From 14 to 27 ℃, intensified biological carbon can remove AOC better compared with granular activated carbon (GAC). Under identical TERC, intensified technique increases more than 10% AOC reduction. 展开更多
关键词 activated carbon assimilable organic carbon empty bed contact time advanced water treatment
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TEGAFUR PLUS MMC OR ACNU IN THE TREATMENT OF ADVANCED GASTRIC CANCER-A PILOT STUDY
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作者 张达荣 萧树东 +1 位作者 江绍基 Minoru Kurihara 《Chinese Journal of Cancer Research》 SCIE CAS CSCD 1990年第4期63-66,共4页
Twenty four cases of advanced gastric cancer were divided into two groups according to the general condition of the patients (PS 0-2 and 3-4), further subdivided into localized abdominal form, liver metastatic form, a... Twenty four cases of advanced gastric cancer were divided into two groups according to the general condition of the patients (PS 0-2 and 3-4), further subdivided into localized abdominal form, liver metastatic form, ascitic form and distant metastatic form. These patients were allocated randomly into Regimen A or B. Regimen A: Tegafur 600 mg daily and Mitomycin C (MMC) 5 mg/m2/1-2 weeks. Regimen B: Tegafur 600 mg daily and ACNU (Nimustine, water-soluble Nitrosourea) 60 mg/week for 2 weeks. After a course of ACNU, it was with drawn for 4 weeks and then resumed again. The response rate of Regimen A was 3/11 (27%), that of Regimen B was 3/13 (23%). 展开更多
关键词 ACNU TEGAFUR PLUS MMC OR ACNU IN THE treatment OF advanced GASTRIC CANCER-A PILOT STUDY BCNU MMC
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Mitomycin C and capecitabine: An additional option as an advanced line therapy in patients with metastatic colorectal cancer
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作者 Gil Mullin Michal Sternschuss +2 位作者 Yosef Landman Aaron Sulkes Baruch Brenner 《World Journal of Gastrointestinal Oncology》 SCIE 2023年第11期1913-1924,共12页
BACKGROUND In recent years survival of patients with metastatic colorectal cancer(mCRC),though still limited,has improved significantly;clearly,when the disease becomes refractory to standard regimens,additional treat... BACKGROUND In recent years survival of patients with metastatic colorectal cancer(mCRC),though still limited,has improved significantly;clearly,when the disease becomes refractory to standard regimens,additional treatment options are needed.Studies have shown that mitomycin C(MMC),an antitumor antibiotic,and capecitabine,a precursor of 5-fluorouracil,may act synergistically in combination.The efficacy of MMC/capecitabine has been demonstrated in the first-line setting,but only a few small studies have tested it in the advanced-line setting,with contradictory results.received a median of 2 MMC/capecitabine cycles(range 0.5-9.0).Thirty-four patients(28.6%)experienced grade≥3 toxicity,including 2(1.7%)with grade 4;there was no drug-related mortality.The objective response rate was 0.8%,and the disease control rate,24.4%.Median progression-free survival(PFS)was 2.1 mo(range 0.2-20.3),and median overall survival,4.8 mo(range 0.2-27.5).The 6-month overall survival rate was 44%;8.7%of patients remained progression-free.Factors associated with longer PFS were lower gamma-glutamyl transferase level(P=0.030)and primary tumor location in the left colon(P=0.017).Factors associated with longer overall survival were lower gamma-glutamyl transferase level(P=0.022),left-colon tumor location(P=0.044),low-to-moderate histological grade(P=0.012),Eastern Cooperative Oncology Group performance status 0-1(P=0.036),and normal bilirubin level(P=0.047).CONCLUSION MMC/capecitabine is an active,available,and relatively safe regimen for use beyond standard lines of therapy in mCRC.Several clinical and laboratory parameters can identify patients more likely to benefit. 展开更多
关键词 Colorectal cancer Metastatic cancer Chemotherapy Mitomycin C/Capecitabine advanced line treatment
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Occurrences of Glucocorticoids in Aquatic Environment and Their Removal during Wastewater Treatment
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作者 吴清晨 吴世闵 +5 位作者 张茵茵 ANDERE Clement Miruka 朱大海 张艾 刘亚男 薛罡 《Journal of Donghua University(English Edition)》 CAS 2023年第3期293-318,共26页
Glucocorticoids(GCs) are a group of endocrine-disrupting compounds(EDCs) frequently prescribed against various medical conditions.Recently,GCs have been shown to be effective in managing septic shock in patients infec... Glucocorticoids(GCs) are a group of endocrine-disrupting compounds(EDCs) frequently prescribed against various medical conditions.Recently,GCs have been shown to be effective in managing septic shock in patients infected with the 2019 novel coronavirus(COVID-19).Due to colossal consumption and potential risks to aquatic organisms,GCs have immensely attracted the focus of the scientific research community as a water pollutant.Therefore,the aim of this paper is to review the current knowledge on the occurrence of various GCs in the aquatic environment and their removal during wastewater treatment.A variety of GCs are ubiquitous in surface water,hospital wastewater,and sewage water worldwide.And the minimum concentration in volume is below 0.01 ng/L,and the maximum one is 10 000 ng/L,and enter the environment through hospital and urban wastewater discharging.Compared with natural GCs,higher risks to aquatic environments could be induced by synthetic GCs.The current activated sludge processes used in wastewater treatment plants(WWTPs) are not fully effective in eliminating GCs,some of which may further increase the risk of GC in the environment.In comparison with the aerobic process in WWTPs,the anaerobic and anoxic processes were found to be more efficient for GC degradation.Of the studied GCs,fluticasone propionate,clobetasol propionate,fluocinolone acetonide,and triamcinolone acetonide need more attention due to their low removal efficiencies and strong toxicity.Among the advanced treatment processes,reverse osmosis,ultraviolet irradiation,CaO_(2),and plasma could achieve significant GC activity removal while micro/ultra-filtration,chlorination,and ozonation were less efficient. 展开更多
关键词 glucocorticoid(GC) endocrine disrupting compound(EDC) wastewater treatment plant(WWTP) advanced wastewater treatment
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Clinical efficacy and tolerance of sunitinib in the treatment of advanced renal cell carcinoma
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作者 施国海 《外科研究与新技术》 2011年第4期239-239,共1页
Objective To evaluate the clinical efficacy and side effects of sunitinib in treatment of advanced renal cell carcinoma. Methods Forty-five patients with advanced renal cell carcinorna and an average age of 48. 6 yrs ... Objective To evaluate the clinical efficacy and side effects of sunitinib in treatment of advanced renal cell carcinoma. Methods Forty-five patients with advanced renal cell carcinorna and an average age of 48. 6 yrs were treated with sunitinib. of the study group。 展开更多
关键词 Clinical efficacy and tolerance of sunitinib in the treatment of advanced renal cell carcinoma CELL
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Wastewater Treatment for Removal of Recalcitrant Compounds:A Hybrid Process for Decolorization and Biodegradation of Dyes 被引量:11
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作者 Carolyn Palma Andrea Carvajal +1 位作者 Carlos Vasquez Elsa Contreras 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2011年第4期621-625,共5页
While conventional wastewater treatments for urban effluents are fairly routine and have proved highly effective,industrial wastewater requires more complex and specific treatments.This paper provides a technological ... While conventional wastewater treatments for urban effluents are fairly routine and have proved highly effective,industrial wastewater requires more complex and specific treatments.This paper provides a technological strategy for removal of recalcitrant contaminants based on a hybrid treatment system.The model effluent containing a binary mixture of synthetic dyes is treated by a combination of a preliminary physicochemical stage followed by a biological stage based on ligninolytic enzymes produced by Phanerochaete chrysosporium.This proposal includes biosorption onto peat as pretreatment,which decreases the volume and concentration to be treated in the biological reactor,thereby obtaining a completely decolorized effluent.The treated wastewater can therefore be reused in the dyeing baths with the consequent saving of water resources. 展开更多
关键词 wastewater hybrid and advanced treatment BIOPROCESS
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New advances in targeted gastric cancer treatment 被引量:15
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作者 Daniela Cornelia Lazar Sorina Taban +2 位作者 Marioara Cornianu Alexandra Faur Adrian Goldis 《World Journal of Gastroenterology》 SCIE CAS 2016年第30期6776-6799,共24页
Despite a decrease in incidence over past decades,gastric cancer remains a major global health problem. In the more recent period, survival has shown only minor improvement, despite significant advances in diagnostic ... Despite a decrease in incidence over past decades,gastric cancer remains a major global health problem. In the more recent period, survival has shown only minor improvement, despite significant advances in diagnostic techniques, surgical and chemotherapeutic approaches, the development of novel therapeutic agents and treatment by multidisciplinary teams. Because multiple genetic mutations, epigenetic alterations, and aberrant molecular signalling pathways are involved in the development of gastric cancers, recent research has attempted to determine the molecular heterogeneity responsible for the processes of carcinogenesis, spread and metastasis. Currently, some novel agents targeting a part of these dysfunctional molecular signalling pathways have already been integrated into the standard treatment of gastric cancer, whereas others remain in phases of investigation within clinical trials. It is essential to identify the unique molecular patterns of tumours and specific biomarkers to develop treatments targeted to the individual tumour behaviour. This review analyses the global impact of gastric cancer, as well as the role of Helicobacter pylori infection and the efficacy of bacterial eradication in preventing gastric cancer development. Furthermore, the paper discusses the currently available targeted treatments and future directions of research using promising novel classes of molecular agents for advanced tumours. 展开更多
关键词 Gastric cancer Helicobacter pylori infection Chemotherapy Targeted therapy Clinical trials New treatment advances
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Pancreatic cancer: Advances in treatment 被引量:8
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作者 Somala Mohammed George Van Buren Ⅱ William E Fisher 《World Journal of Gastroenterology》 SCIE CAS 2014年第28期9354-9360,共7页
Pancreatic cancer is a leading cause of cancer mortality and the incidence of this disease is expected to continue increasing.While patients with pancreatic cancer have traditionally faced a dismal prognosis,over the ... Pancreatic cancer is a leading cause of cancer mortality and the incidence of this disease is expected to continue increasing.While patients with pancreatic cancer have traditionally faced a dismal prognosis,over the past several years various advances in diagnosis and treatment have begun to positively impact this disease.Identification of effective combinations of existing chemotherapeutic agents,such as the FOLFIRINOX and the gemcitabine+nab-paclitaxel regimen,has improved survival for selected patients although concerns regarding their toxicity profiles remain.A better understanding of pancreatic carcinogenesis has identified several pre-malignant precursor lesions,such as pancreatic intraepithelial neoplasias,intraductal papillary mucinous neoplasms,and cystic neoplasms.Imaging technology has also evolved dramatically so as to allow early detection of these lesions and thereby facilitate earlier management.Surgery remains a cornerstone of treatment for patients with resectable pancreatic tumors,and advances in surgical technique have allowed patients to undergo resection with decreasing perioperative morbidity and mortality.Surgery has also become feasible in selected patients with borderline resectable tumors as a result of neoadjuvant therapy.Furthermore,pancreatectomy involving vascular reconstruction and pancreatectomy with minimally invasive techniques have demonstrated safety without significantly compromising oncologic outcomes.Lastly,a deeper understanding of molecular aberrations contributing to the development of pancreatic cancer shows promise for future development of more targeted and safe therapeutic agents. 展开更多
关键词 Pancreatic cancer PANCREATICODUODENECTOMY treatment advances Pancreatic oncology Chemotherapy FOLFIRINOX Pancreatic resection
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Treatment of pharmaceutical wastewater containing recalcitrant compounds in a Fenton-coagulation process 被引量:3
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作者 Bukuru Godefroid 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2006年第3期459-463,共5页
The advanced treatment using integrated Fenton's reaction and coagulation process was investigated in this study. Before the advancement, the pharmaceutical wastewater containing lincomycin hydrochloride was pretreat... The advanced treatment using integrated Fenton's reaction and coagulation process was investigated in this study. Before the advancement, the pharmaceutical wastewater containing lincomycin hydrochloride was pretreated by UASB (upflow anaerobic sludge bed) and a SBR (sequencing batch reactor) process. The residual recalcitrant compounds, measured by gas chromatographymass spectrometry (GC-MS), mainly consisted of alcohols, phenols, and nitrogenous and sulfur compounds. The experimental results indicated that when the Fenton's reaction was conducted at pH=3.0, H2O2CODOcr=0.27, H2O2/Fe^2+=3:1 and 30 min of reaction time, and the coagulation process operated at a sulfate aluminum concentration of 800 mg/L and pH value of 5.0, the color and COD in the wastewater decreased by 94% and 73%, respectively; with a finale COD concentration of 267 mg/L and color level of 40 units, meeting the secondary standard of GB8978-1996 for industrial wastewater. 展开更多
关键词 pharmaceutical wastewater GC-MS recalcitrant compounds Fenton's reaction coagulation process advanced wastewater treatment
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Contemporary management of locally advanced rectal cancer:Resolving issues, controversies and shifting paradigms 被引量:11
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作者 Aeris Jane D.Nacion Youn Young Park Nam Kyu Kim 《Chinese Journal of Cancer Research》 SCIE CAS CSCD 2018年第1期131-146,共16页
Advancements in rectal cancer treatment have resulted in improvement only in locoregional control and have failed to address distant relapse, which is the predominant mode of treatment failure in rectal cancer. As the... Advancements in rectal cancer treatment have resulted in improvement only in locoregional control and have failed to address distant relapse, which is the predominant mode of treatment failure in rectal cancer. As the efficacy of conventional chemoradiotherapy(CRT) followed by total mesorectal excision(TME) reaches a plateau, the need for alternative strategies in locally advanced rectal cancer(LARC) has grown in relevance. Several novel strategies have been conceptualized to address this issue, including: 1) neoadjuvant induction and consolidation chemotherapy before CRT; 2) neoadjuvant chemotherapy alone to avoid the sequelae of radiation; and 3) nonoperative management for patients who achieved pathological or clinical complete response after CRT. This article explores the issues, recent advances and paradigm shifts in the management of LARC and emphasizes the need for a personalized treatment plan for each patient based on tumor stage, location, gene expression and quality of life. 展开更多
关键词 Locally advanced rectal cancer neoadjuvant treatment chemoradiotherapy
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