The textile industry is constantly evolving,and advancements in technology are playing a pivotal role in shaping the development and use of textile binders.According to Reports and Insights,the global textile binder m...The textile industry is constantly evolving,and advancements in technology are playing a pivotal role in shaping the development and use of textile binders.According to Reports and Insights,the global textile binder market is expected to reach a value of USD 5.33 billion by 2032,exhibiting a healthy CAGR of 4.4%.This growth is fueled by a confluence of factors,with technological innovation at the forefront.Let's delve into how these advancements are impacting the landscape of textile binders。展开更多
The healthcare sector is advancing in many aspects,including smart devices,surgical robots,AR/VR consultation,etc.Medical textiles are one such aspect where we have observed tremendous growth in innovation.Before the ...The healthcare sector is advancing in many aspects,including smart devices,surgical robots,AR/VR consultation,etc.Medical textiles are one such aspect where we have observed tremendous growth in innovation.Before the pandemic,the CAGR of patent filing in medical textiles was~12.5%.Postpandemic,it increased to 42.6%.From the patent publishing data,we saw that the US,Japan,India,and Germany are the top four countries in which innovations in medical textiles are on the rise.The extent of the growth is due to the constant improvements and innovations in both textile technology and medical materials.展开更多
The world of healthcare is constantly evolving,and one area that has seen significant advancements in recent years is clinical pharmacy practice.1 In the past,pharmacists were mainly responsible for dispensing medicat...The world of healthcare is constantly evolving,and one area that has seen significant advancements in recent years is clinical pharmacy practice.1 In the past,pharmacists were mainly responsible for dispensing medications and ensuring that patients understood how to use them safely.However,the role of clinical pharmacists has expanded significantly in recent years,and they now play a critical role in optimizing medication regimens,providing personalized patient counselling,and collaborating with other healthcare professionals to improve patient outcomes.2-3 In the extension of the role of the clinical pharmacist,nowadays health economics is also added,which includes cost-benefit analysis,cost-effectiveness analysis,cost-utilization analysis and costminimization analysis,which will ultimately help the policy and decision makers to make the cost of the drugs affordable,so that all the patient population can avail the benefits.展开更多
The history and current status of research and development of wave energy in the world is briefly introduced. The main problems existing in these studies are pointed out. The description is focused on the current stat...The history and current status of research and development of wave energy in the world is briefly introduced. The main problems existing in these studies are pointed out. The description is focused on the current status and the advancements achieved in China. After analysis of the wave energy resources and practical situations in China, it is pointed out that the studies on wave energy should be not only concentrated on the conversion efficiency and costs of wave energy devices, but also focused on the technology of independent operation and stable output of electricity. Finally, the perspectives of application of wave energy in China are discussed.展开更多
This review article aims to analyze and evaluate the advantages, shortcomings, technological advancements and hereafter prospects in welding and processing of magnesium and its alloys. Studies have accounted that repl...This review article aims to analyze and evaluate the advantages, shortcomings, technological advancements and hereafter prospects in welding and processing of magnesium and its alloys. Studies have accounted that replacing other metals with Mg alloys will bring about in monumental weight reduction with significant addition in strength that could lead to dramatic transformation of metallic era of 21st century and onwards. However,wide application of Mg and its alloys depends on the development of advanced welding &joining technologies. The current paradigm and progress in welding,joining and processing of magnesium and its alloys are reviewed,and research trend in this field is briefly discussed.展开更多
Neurological diseases and injuries present some of the great- est challenges in modern medicine, often causing irrevers- ible and lifelong burdens in the people whom they afflict. Conditions of stroke, traumatic brain...Neurological diseases and injuries present some of the great- est challenges in modern medicine, often causing irrevers- ible and lifelong burdens in the people whom they afflict. Conditions of stroke, traumatic brain injury, spinal cord injury, and neurodegenerative diseases have devastating con- sequences on millions of people each year, and yet there are currently no therapies or interventions that can repair the structure of neural circuits and restore neural tissue function in the brain and spinal cord. Despite the challenges of over- coming these limitations, there are many new approaches under development that hold much promise. Neural tissue engineering aims to restore and influence the function of damaged or diseased neural tissue generally through the use of stem cells and biomaterials. Many types of biomaterials may be implemented in various designs to influence the survival, differentiation, and function of developing stem cells, as well as to guide neurite extension and morphological architecture of cell cultures. Such designs may aim to reca- pitulate the cellular interactions, extracellular matrix char- acteristics, biochemical factors, and sequences of events that occur in neurodevelopment, in addition to supporting cell survival, differentiation, and integration into innate neural tissue.展开更多
Ultrasound is extensively studied for biomedical engineering applications.As the core part of the ultrasonic system,the ultrasound transducer plays a significant role.For the purpose of meeting the requirement of prec...Ultrasound is extensively studied for biomedical engineering applications.As the core part of the ultrasonic system,the ultrasound transducer plays a significant role.For the purpose of meeting the requirement of precision medicine,the main challenge for the development of ultrasound transducer is to further enhance its performance.In this article,an overview of recent developments in ultrasound transducer technologies that use a variety of material strategies and device designs based on both the piezoelectric and photoacoustic mechanisms is provided.Practical applications are also presented,including ultrasound imaging,ultrasound therapy,particle/cell manipulation,drug delivery,and nerve stimulation.Finally,perspectives and opportunities are also highlighted.展开更多
The rapid evolution of electric vehicles(EVs)highlights the critical role of bat-tery technology in promoting sustainable transportation.This review offers a comprehensive introduction to the diverse landscape of batt...The rapid evolution of electric vehicles(EVs)highlights the critical role of bat-tery technology in promoting sustainable transportation.This review offers a comprehensive introduction to the diverse landscape of batteries for EVs.In particular,it examines the impressive array of available battery technologies,focusing on the predominance of lithium-based batteries,such as lithium-ion and lithium-metal variants.Additionally,it explores battery technologies beyond lithium(“post-lithium”),including aluminum,sodium,and magnesium batter-ies.The potential of solid-state batteries is also discussed,along with the current status of various battery types in EV applications.The review further addresses end-of-life treatment strategies for EV batteries,including reuse,remanufactur-ing,and recycling,which are essential for mitigating the environmental impact of batteries and ensuring sustainable lifecycle management.Finally,market per-spectives and potential future research directions for battery technologies in EVs are also discussed.展开更多
This paper presents a review of the position-sensitive detector(PSD) sensor, covering different types of PSD and recent works related to this field. Furthermore, it explains the theoretical concepts and provides infor...This paper presents a review of the position-sensitive detector(PSD) sensor, covering different types of PSD and recent works related to this field. Furthermore, it explains the theoretical concepts and provides information about its structure and principles of operation. Moreover, it includes the main information about the available commercial PSDs from different companies, along with a comparison between the common modules. The PSD features include high position resolution, fast response, and a wide dynamic range. These features make it suitable for various fields and applications, such as imaging, spectrometry, spectroscopy and others.展开更多
Organic dye pollutants present in wastewater pose a significant global challenge.Among pollutants,the synthetic dye Rhodamine B(RB)stands out due to its non-biodegradable nature and associated neurotoxic,carcinogenic,...Organic dye pollutants present in wastewater pose a significant global challenge.Among pollutants,the synthetic dye Rhodamine B(RB)stands out due to its non-biodegradable nature and associated neurotoxic,carcinogenic,and respiratory irritant properties.Extensive research has been conducted on the efficacy of adsorption and photodegradation techniques for the removal of RB from wastewater.While adsorption and advanced oxidation processes(AOPs)have gained considerable attention for their effectiveness in recent years,the underlying behaviors and mechanisms of these technologies remain incompletely understood.Therefore,a comprehensive of recent research progress in this domain is imperative to clarify the basics and present the up-to-date achievements.This review provides an in-depth exploration of the fundamentals,advancements,and future trajectories of RB wastewater treatment technologies,mainly encompassing adsorption and photodegradation.This work starts with a general introduction of outlining the sources,toxicity,and diverse applicable removal strategies.Subsequently,it thoroughly examines crucial techniques within non-photochemical,photochemical,and adsorption technologies,such as UV light assisted AOP,catalyst assisted AOP,ozonation,Fenton system,electrochemical AOP,and adsorption technology.The primary objective is to furnish a broad overview of these techniques,elucidating their effectiveness,limitations,and applicability.Following this,the review encapsulates state-of-theart computational simulations pertaining to RB adsorption and interactions with clays and other adsorbents.Lastly,it delves into column adsorption of RB dye,and elucidates various influencing factors,including bed height,feed concentration,pollutant(RB)feeding or flow rate,and column regeneration.This panoramic review aims to provide valuable insights into suitable techniques,research gaps,and the applicability of nonphotochemical,photochemical,and adsorption technologies in the treatment of wastewater containing RB dye.展开更多
This paper presents a comprehensive analysis of global human trafficking trends over a twenty-year period, leveraging a robust dataset from the Counter Trafficking Data Collaborative (CTDC). The study unfolds in a sys...This paper presents a comprehensive analysis of global human trafficking trends over a twenty-year period, leveraging a robust dataset from the Counter Trafficking Data Collaborative (CTDC). The study unfolds in a systematic manner, beginning with a detailed data collection phase, where ethical and legal standards for data usage and privacy are strictly observed. Following collection, the data undergoes a rigorous preprocessing stage, involving cleaning, integration, transformation, and normalization to ensure accuracy and consistency for analysis. The analytical phase employs time-series analysis to delineate historical trends and utilizes predictive modeling to forecast future trajectories of human trafficking using the advanced analytical capabilities of Power BI. A comparative analysis across regions—Africa, the Americas, Asia, and Europe—is conducted to identify and visualize the distribution of human trafficking, dissecting the data by victim demographics, types of exploitation, and duration of victimization. The findings of this study not only offer a descriptive and predictive outlook on trafficking patterns but also provide insights into the regional nuances that influence these trends. The article underscores the prevalence and persistence of human trafficking, identifies factors contributing to its evolution, and discusses the implications for policy and law enforcement. By integrating a methodological approach with quantitative analysis, this research contributes to the strategic planning and resource allocation for combating human trafficking. It highlights the necessity for continued research and international cooperation to effectively address and mitigate this global issue. The implications of this research are significant, offering actionable insights for policymakers, law enforcement, and advocates in the ongoing battle against human trafficking.展开更多
Surveillance systems are vital for detecting,managing,and mitigating infectious disease outbreaks.This review highlights the importance of modern technologies like AI and big data in enhancing surveillancecapabilities...Surveillance systems are vital for detecting,managing,and mitigating infectious disease outbreaks.This review highlights the importance of modern technologies like AI and big data in enhancing surveillancecapabilities.It underscores the need for global collaboration and examines the role of surveillance in diseases likeinfluenza,Ebola,and COVID-19.Technological innovations such as geospatial mapping and wearable healthdevices are transforming disease control,though they raise ethical concerns about privacy.Continuousadvancements and ethical safeguards are crucial for effective surveillance and global health protection.展开更多
BIG models or foundation models are rapidly emerging as a key force in advancing intelligent societies[1]–[3]Their significance stems not only from their exceptional ability to process complex data and simulate advan...BIG models or foundation models are rapidly emerging as a key force in advancing intelligent societies[1]–[3]Their significance stems not only from their exceptional ability to process complex data and simulate advanced cognitive functions,but also from their potential to drive innovation across various industries.展开更多
Reinforcement learning(RL) has roots in dynamic programming and it is called adaptive/approximate dynamic programming(ADP) within the control community. This paper reviews recent developments in ADP along with RL and ...Reinforcement learning(RL) has roots in dynamic programming and it is called adaptive/approximate dynamic programming(ADP) within the control community. This paper reviews recent developments in ADP along with RL and its applications to various advanced control fields. First, the background of the development of ADP is described, emphasizing the significance of regulation and tracking control problems. Some effective offline and online algorithms for ADP/adaptive critic control are displayed, where the main results towards discrete-time systems and continuous-time systems are surveyed, respectively.Then, the research progress on adaptive critic control based on the event-triggered framework and under uncertain environment is discussed, respectively, where event-based design, robust stabilization, and game design are reviewed. Moreover, the extensions of ADP for addressing control problems under complex environment attract enormous attention. The ADP architecture is revisited under the perspective of data-driven and RL frameworks,showing how they promote ADP formulation significantly.Finally, several typical control applications with respect to RL and ADP are summarized, particularly in the fields of wastewater treatment processes and power systems, followed by some general prospects for future research. Overall, the comprehensive survey on ADP and RL for advanced control applications has d emonstrated its remarkable potential within the artificial intelligence era. In addition, it also plays a vital role in promoting environmental protection and industrial intelligence.展开更多
Maillard reaction(MR)is a non-enzymatic browning reaction commonly seen in food processing,which occurs between reducing sugars and compounds with amino groups.Despite certain advantages based on Maillard reaction pro...Maillard reaction(MR)is a non-enzymatic browning reaction commonly seen in food processing,which occurs between reducing sugars and compounds with amino groups.Despite certain advantages based on Maillard reaction products(MRPs)found in some food for health and storage application have appeared,however,the MR occurring in human physiological environment can produce advanced glycation end products(AGEs)by non-enzymatic modification of macromolecules such as proteins,lipids and nucleic acid,which could change the structure and functional activity of the molecules themselves.In this review,we take AGEs as our main object,on the one hand,discuss physiologic aging,that is,age-dependent covalent cross-linking and modification of proteins such as collagen that occur in eyes and skin containing connective tissue.On the other hand,pathological aging associated with autoimmune and inflammatory diseases,neurodegenerative diseases,diabetes and diabetic nephropathy,cardiovascular diseases and bone degenerative diseases have been mainly proposed.Based on the series of adverse effects of accelerated aging and disease pathologies caused by MRPs,the possible harm caused by some MR can be slowed down or inhibited by artificial drug intervention,dietary pattern and lifestyle control.It also stimulates people's curiosity to continue to explore the potential link between the MR and human aging and health,which should be paid more attention to for the development of life sciences.展开更多
Four major studies(Checkmate577,Keynote-590,Checkmate649 and Attraction-4)of locally advanced esophageal cancer published in 2020 have established the importance of immunotherapy,represented by anti-programmed death p...Four major studies(Checkmate577,Keynote-590,Checkmate649 and Attraction-4)of locally advanced esophageal cancer published in 2020 have established the importance of immunotherapy,represented by anti-programmed death protein(PD)-1 in postoperative adjuvant treatment and advanced first-line treatment of locally advanced or advanced esophageal cancer and esophagogastric junction cancer,from the aspects of proof of concept,long-term survival,overall survival rate and progression-free survival.For unresectable or inoperable nonmetastatic esophageal cancer,concurrent radiotherapy and chemotherapy is the standard treatment recommended by various guidelines.Because its curative effect is still not ideal,it is necessary to explore radical radiotherapy and chemotherapy in the future,and it is considered to be promising to combine them with immunotherapeutic drugs such as anti-PD-1.This paper mainly discusses how to combine radical concurrent radiotherapy and chemotherapy with immunotherapy for unresectable local advanced esophageal cancer.展开更多
BACKGROUND The relation between orthodontic treatment and temporomandibular disorders(TMDs)is under debate;the management of TMD during orthodontic treatment has always been a challenge.If TMD symptoms occur during or...BACKGROUND The relation between orthodontic treatment and temporomandibular disorders(TMDs)is under debate;the management of TMD during orthodontic treatment has always been a challenge.If TMD symptoms occur during orthodontic treatment,an immediate pause of orthodontic adjustments is recommended;the treatment can resume when the symptoms are managed and stabilized.CASE SUMMARY This case report presents a patient(26-year-old,female)with angle class I,skeletal class II and TMDs.The treatment was a hybrid of clear aligners,fixed appliances and temporary anchorage devices(TADs).After 3 mo resting and treatment on her TMD,the patient’s TMD symptom alleviated,but her anterior occlusion displayed deep overbite.Therefore,the fixed appliances with TAD were used to correct the anterior deep-bite and level maxillary and mandibular deep curves.After the levelling,the patient showed dual bite with centric relation and maximum intercuspation discrepancy on her occlusion.After careful examination of temporomandibular joints(TMJ)position,the stable bite splint and Invisible Mandibular Advancement appliance were used to reconstruct her occlusion.Eventually,the improved facial appearance and relatively stable occlusion were achieved.The 1-year follow-up records showed there was no obvious change in TMJ morphology,and her occlusion was stable.CONCLUSION TMD screening and monitoring is of great clinical importance in the TMD susceptible patients.Hybrid treatment with clear aligners and fixed appliances and TADs is an effective treatment modality for the complex cases.展开更多
The development of intestinal anastomosis techniques,including hand suturing,stapling,and compression anastomoses,has been a significant advancement in surgical practice.These methods aim to prevent leakage and minimi...The development of intestinal anastomosis techniques,including hand suturing,stapling,and compression anastomoses,has been a significant advancement in surgical practice.These methods aim to prevent leakage and minimize tissue fibrosis,which can lead to stricture formation.The healing process involves various phases:hemostasis and inflammation,proliferation,and remodeling.Mechanical staplers and sutures can cause inflammation and fibrosis due to the release of profibrotic chemokines.Compression anastomosis devices,including those made of nickel-titanium alloy,offer a minimally invasive option for various surgical challenges and have shown safety and efficacy.However,despite advancements,anastomotic techniques are evaluated based on leakage risk,with complications being a primary concern.Newer devices like Magnamosis use magnetic rings for compression anastomosis,demonstrating greater strength and patency compared to stapling.Magnetic technology is also being explored for other medical treatments.While there are promising results,particularly in animal models,the realworld application in humans is limited,and further research is needed to assess their safety and practicality.展开更多
文摘The textile industry is constantly evolving,and advancements in technology are playing a pivotal role in shaping the development and use of textile binders.According to Reports and Insights,the global textile binder market is expected to reach a value of USD 5.33 billion by 2032,exhibiting a healthy CAGR of 4.4%.This growth is fueled by a confluence of factors,with technological innovation at the forefront.Let's delve into how these advancements are impacting the landscape of textile binders。
文摘The healthcare sector is advancing in many aspects,including smart devices,surgical robots,AR/VR consultation,etc.Medical textiles are one such aspect where we have observed tremendous growth in innovation.Before the pandemic,the CAGR of patent filing in medical textiles was~12.5%.Postpandemic,it increased to 42.6%.From the patent publishing data,we saw that the US,Japan,India,and Germany are the top four countries in which innovations in medical textiles are on the rise.The extent of the growth is due to the constant improvements and innovations in both textile technology and medical materials.
文摘The world of healthcare is constantly evolving,and one area that has seen significant advancements in recent years is clinical pharmacy practice.1 In the past,pharmacists were mainly responsible for dispensing medications and ensuring that patients understood how to use them safely.However,the role of clinical pharmacists has expanded significantly in recent years,and they now play a critical role in optimizing medication regimens,providing personalized patient counselling,and collaborating with other healthcare professionals to improve patient outcomes.2-3 In the extension of the role of the clinical pharmacist,nowadays health economics is also added,which includes cost-benefit analysis,cost-effectiveness analysis,cost-utilization analysis and costminimization analysis,which will ultimately help the policy and decision makers to make the cost of the drugs affordable,so that all the patient population can avail the benefits.
文摘The history and current status of research and development of wave energy in the world is briefly introduced. The main problems existing in these studies are pointed out. The description is focused on the current status and the advancements achieved in China. After analysis of the wave energy resources and practical situations in China, it is pointed out that the studies on wave energy should be not only concentrated on the conversion efficiency and costs of wave energy devices, but also focused on the technology of independent operation and stable output of electricity. Finally, the perspectives of application of wave energy in China are discussed.
基金Sponsored by the State Key Laboratory of Advanced Welding and Joining,Harbin Institute of Technology(Grant No.AWJ-Z16-05)
文摘This review article aims to analyze and evaluate the advantages, shortcomings, technological advancements and hereafter prospects in welding and processing of magnesium and its alloys. Studies have accounted that replacing other metals with Mg alloys will bring about in monumental weight reduction with significant addition in strength that could lead to dramatic transformation of metallic era of 21st century and onwards. However,wide application of Mg and its alloys depends on the development of advanced welding &joining technologies. The current paradigm and progress in welding,joining and processing of magnesium and its alloys are reviewed,and research trend in this field is briefly discussed.
文摘Neurological diseases and injuries present some of the great- est challenges in modern medicine, often causing irrevers- ible and lifelong burdens in the people whom they afflict. Conditions of stroke, traumatic brain injury, spinal cord injury, and neurodegenerative diseases have devastating con- sequences on millions of people each year, and yet there are currently no therapies or interventions that can repair the structure of neural circuits and restore neural tissue function in the brain and spinal cord. Despite the challenges of over- coming these limitations, there are many new approaches under development that hold much promise. Neural tissue engineering aims to restore and influence the function of damaged or diseased neural tissue generally through the use of stem cells and biomaterials. Many types of biomaterials may be implemented in various designs to influence the survival, differentiation, and function of developing stem cells, as well as to guide neurite extension and morphological architecture of cell cultures. Such designs may aim to reca- pitulate the cellular interactions, extracellular matrix char- acteristics, biochemical factors, and sequences of events that occur in neurodevelopment, in addition to supporting cell survival, differentiation, and integration into innate neural tissue.
基金supported by the Natural Science Foundation of China (Grant nos.11774117 and 12102140)Shenzhen Basic Science Research (JCYJ20200109110006136)China Postdoctoral Science Foundation (2021M70130).
文摘Ultrasound is extensively studied for biomedical engineering applications.As the core part of the ultrasonic system,the ultrasound transducer plays a significant role.For the purpose of meeting the requirement of precision medicine,the main challenge for the development of ultrasound transducer is to further enhance its performance.In this article,an overview of recent developments in ultrasound transducer technologies that use a variety of material strategies and device designs based on both the piezoelectric and photoacoustic mechanisms is provided.Practical applications are also presented,including ultrasound imaging,ultrasound therapy,particle/cell manipulation,drug delivery,and nerve stimulation.Finally,perspectives and opportunities are also highlighted.
基金Natural Sciences and Engineering Research Council of Canada(NSERC)Fonds de Recherche du Quebec-Nature et Technologies(FRQNT)+3 种基金Centre Quebecois sur les Materiaux Fonctionnels(CQMF)Reseau Quebecois sur l’energie Intelligente(RQEI)Ecole de Technologie Superieure(ETS)Institut National de la Recherche Scientifique(INRS)。
文摘The rapid evolution of electric vehicles(EVs)highlights the critical role of bat-tery technology in promoting sustainable transportation.This review offers a comprehensive introduction to the diverse landscape of batteries for EVs.In particular,it examines the impressive array of available battery technologies,focusing on the predominance of lithium-based batteries,such as lithium-ion and lithium-metal variants.Additionally,it explores battery technologies beyond lithium(“post-lithium”),including aluminum,sodium,and magnesium batter-ies.The potential of solid-state batteries is also discussed,along with the current status of various battery types in EV applications.The review further addresses end-of-life treatment strategies for EV batteries,including reuse,remanufactur-ing,and recycling,which are essential for mitigating the environmental impact of batteries and ensuring sustainable lifecycle management.Finally,market per-spectives and potential future research directions for battery technologies in EVs are also discussed.
文摘This paper presents a review of the position-sensitive detector(PSD) sensor, covering different types of PSD and recent works related to this field. Furthermore, it explains the theoretical concepts and provides information about its structure and principles of operation. Moreover, it includes the main information about the available commercial PSDs from different companies, along with a comparison between the common modules. The PSD features include high position resolution, fast response, and a wide dynamic range. These features make it suitable for various fields and applications, such as imaging, spectrometry, spectroscopy and others.
文摘Organic dye pollutants present in wastewater pose a significant global challenge.Among pollutants,the synthetic dye Rhodamine B(RB)stands out due to its non-biodegradable nature and associated neurotoxic,carcinogenic,and respiratory irritant properties.Extensive research has been conducted on the efficacy of adsorption and photodegradation techniques for the removal of RB from wastewater.While adsorption and advanced oxidation processes(AOPs)have gained considerable attention for their effectiveness in recent years,the underlying behaviors and mechanisms of these technologies remain incompletely understood.Therefore,a comprehensive of recent research progress in this domain is imperative to clarify the basics and present the up-to-date achievements.This review provides an in-depth exploration of the fundamentals,advancements,and future trajectories of RB wastewater treatment technologies,mainly encompassing adsorption and photodegradation.This work starts with a general introduction of outlining the sources,toxicity,and diverse applicable removal strategies.Subsequently,it thoroughly examines crucial techniques within non-photochemical,photochemical,and adsorption technologies,such as UV light assisted AOP,catalyst assisted AOP,ozonation,Fenton system,electrochemical AOP,and adsorption technology.The primary objective is to furnish a broad overview of these techniques,elucidating their effectiveness,limitations,and applicability.Following this,the review encapsulates state-of-theart computational simulations pertaining to RB adsorption and interactions with clays and other adsorbents.Lastly,it delves into column adsorption of RB dye,and elucidates various influencing factors,including bed height,feed concentration,pollutant(RB)feeding or flow rate,and column regeneration.This panoramic review aims to provide valuable insights into suitable techniques,research gaps,and the applicability of nonphotochemical,photochemical,and adsorption technologies in the treatment of wastewater containing RB dye.
文摘This paper presents a comprehensive analysis of global human trafficking trends over a twenty-year period, leveraging a robust dataset from the Counter Trafficking Data Collaborative (CTDC). The study unfolds in a systematic manner, beginning with a detailed data collection phase, where ethical and legal standards for data usage and privacy are strictly observed. Following collection, the data undergoes a rigorous preprocessing stage, involving cleaning, integration, transformation, and normalization to ensure accuracy and consistency for analysis. The analytical phase employs time-series analysis to delineate historical trends and utilizes predictive modeling to forecast future trajectories of human trafficking using the advanced analytical capabilities of Power BI. A comparative analysis across regions—Africa, the Americas, Asia, and Europe—is conducted to identify and visualize the distribution of human trafficking, dissecting the data by victim demographics, types of exploitation, and duration of victimization. The findings of this study not only offer a descriptive and predictive outlook on trafficking patterns but also provide insights into the regional nuances that influence these trends. The article underscores the prevalence and persistence of human trafficking, identifies factors contributing to its evolution, and discusses the implications for policy and law enforcement. By integrating a methodological approach with quantitative analysis, this research contributes to the strategic planning and resource allocation for combating human trafficking. It highlights the necessity for continued research and international cooperation to effectively address and mitigate this global issue. The implications of this research are significant, offering actionable insights for policymakers, law enforcement, and advocates in the ongoing battle against human trafficking.
文摘Surveillance systems are vital for detecting,managing,and mitigating infectious disease outbreaks.This review highlights the importance of modern technologies like AI and big data in enhancing surveillancecapabilities.It underscores the need for global collaboration and examines the role of surveillance in diseases likeinfluenza,Ebola,and COVID-19.Technological innovations such as geospatial mapping and wearable healthdevices are transforming disease control,though they raise ethical concerns about privacy.Continuousadvancements and ethical safeguards are crucial for effective surveillance and global health protection.
基金the National Natural Science Foundation of China(62103411)the Science and Technology Development Fund of Macao SAR(0093/2023/RIA2,0050/2020/A1)。
文摘BIG models or foundation models are rapidly emerging as a key force in advancing intelligent societies[1]–[3]Their significance stems not only from their exceptional ability to process complex data and simulate advanced cognitive functions,but also from their potential to drive innovation across various industries.
基金supported in part by the National Natural Science Foundation of China(62222301, 62073085, 62073158, 61890930-5, 62021003)the National Key Research and Development Program of China (2021ZD0112302, 2021ZD0112301, 2018YFC1900800-5)Beijing Natural Science Foundation (JQ19013)。
文摘Reinforcement learning(RL) has roots in dynamic programming and it is called adaptive/approximate dynamic programming(ADP) within the control community. This paper reviews recent developments in ADP along with RL and its applications to various advanced control fields. First, the background of the development of ADP is described, emphasizing the significance of regulation and tracking control problems. Some effective offline and online algorithms for ADP/adaptive critic control are displayed, where the main results towards discrete-time systems and continuous-time systems are surveyed, respectively.Then, the research progress on adaptive critic control based on the event-triggered framework and under uncertain environment is discussed, respectively, where event-based design, robust stabilization, and game design are reviewed. Moreover, the extensions of ADP for addressing control problems under complex environment attract enormous attention. The ADP architecture is revisited under the perspective of data-driven and RL frameworks,showing how they promote ADP formulation significantly.Finally, several typical control applications with respect to RL and ADP are summarized, particularly in the fields of wastewater treatment processes and power systems, followed by some general prospects for future research. Overall, the comprehensive survey on ADP and RL for advanced control applications has d emonstrated its remarkable potential within the artificial intelligence era. In addition, it also plays a vital role in promoting environmental protection and industrial intelligence.
基金financially supported by grants from the National Natural Science Foundation of China (82170873,81871095)the National Natural Science Foundation of China (81974503)the Tsinghua University Spring Breeze Fund (20211080005)。
文摘Maillard reaction(MR)is a non-enzymatic browning reaction commonly seen in food processing,which occurs between reducing sugars and compounds with amino groups.Despite certain advantages based on Maillard reaction products(MRPs)found in some food for health and storage application have appeared,however,the MR occurring in human physiological environment can produce advanced glycation end products(AGEs)by non-enzymatic modification of macromolecules such as proteins,lipids and nucleic acid,which could change the structure and functional activity of the molecules themselves.In this review,we take AGEs as our main object,on the one hand,discuss physiologic aging,that is,age-dependent covalent cross-linking and modification of proteins such as collagen that occur in eyes and skin containing connective tissue.On the other hand,pathological aging associated with autoimmune and inflammatory diseases,neurodegenerative diseases,diabetes and diabetic nephropathy,cardiovascular diseases and bone degenerative diseases have been mainly proposed.Based on the series of adverse effects of accelerated aging and disease pathologies caused by MRPs,the possible harm caused by some MR can be slowed down or inhibited by artificial drug intervention,dietary pattern and lifestyle control.It also stimulates people's curiosity to continue to explore the potential link between the MR and human aging and health,which should be paid more attention to for the development of life sciences.
基金Supported by Natural Science Foundation of Fujian Province,No.2021J011259.
文摘Four major studies(Checkmate577,Keynote-590,Checkmate649 and Attraction-4)of locally advanced esophageal cancer published in 2020 have established the importance of immunotherapy,represented by anti-programmed death protein(PD)-1 in postoperative adjuvant treatment and advanced first-line treatment of locally advanced or advanced esophageal cancer and esophagogastric junction cancer,from the aspects of proof of concept,long-term survival,overall survival rate and progression-free survival.For unresectable or inoperable nonmetastatic esophageal cancer,concurrent radiotherapy and chemotherapy is the standard treatment recommended by various guidelines.Because its curative effect is still not ideal,it is necessary to explore radical radiotherapy and chemotherapy in the future,and it is considered to be promising to combine them with immunotherapeutic drugs such as anti-PD-1.This paper mainly discusses how to combine radical concurrent radiotherapy and chemotherapy with immunotherapy for unresectable local advanced esophageal cancer.
基金Natural Science Foundation of Jiangsu Province, No. SBK2021021787the Major Project of the Health Commission ofJiangsu Province, No. ZD2022025and the Key Project of the Nanjing Health Commission, No. ZKX20048.
文摘BACKGROUND The relation between orthodontic treatment and temporomandibular disorders(TMDs)is under debate;the management of TMD during orthodontic treatment has always been a challenge.If TMD symptoms occur during orthodontic treatment,an immediate pause of orthodontic adjustments is recommended;the treatment can resume when the symptoms are managed and stabilized.CASE SUMMARY This case report presents a patient(26-year-old,female)with angle class I,skeletal class II and TMDs.The treatment was a hybrid of clear aligners,fixed appliances and temporary anchorage devices(TADs).After 3 mo resting and treatment on her TMD,the patient’s TMD symptom alleviated,but her anterior occlusion displayed deep overbite.Therefore,the fixed appliances with TAD were used to correct the anterior deep-bite and level maxillary and mandibular deep curves.After the levelling,the patient showed dual bite with centric relation and maximum intercuspation discrepancy on her occlusion.After careful examination of temporomandibular joints(TMJ)position,the stable bite splint and Invisible Mandibular Advancement appliance were used to reconstruct her occlusion.Eventually,the improved facial appearance and relatively stable occlusion were achieved.The 1-year follow-up records showed there was no obvious change in TMJ morphology,and her occlusion was stable.CONCLUSION TMD screening and monitoring is of great clinical importance in the TMD susceptible patients.Hybrid treatment with clear aligners and fixed appliances and TADs is an effective treatment modality for the complex cases.
文摘The development of intestinal anastomosis techniques,including hand suturing,stapling,and compression anastomoses,has been a significant advancement in surgical practice.These methods aim to prevent leakage and minimize tissue fibrosis,which can lead to stricture formation.The healing process involves various phases:hemostasis and inflammation,proliferation,and remodeling.Mechanical staplers and sutures can cause inflammation and fibrosis due to the release of profibrotic chemokines.Compression anastomosis devices,including those made of nickel-titanium alloy,offer a minimally invasive option for various surgical challenges and have shown safety and efficacy.However,despite advancements,anastomotic techniques are evaluated based on leakage risk,with complications being a primary concern.Newer devices like Magnamosis use magnetic rings for compression anastomosis,demonstrating greater strength and patency compared to stapling.Magnetic technology is also being explored for other medical treatments.While there are promising results,particularly in animal models,the realworld application in humans is limited,and further research is needed to assess their safety and practicality.