Taking the advantage of sun glitter(SG)observed from high-resolution satellites Gaofen-1(GF-1)and Gaofen-6(GF-6),a new method named Shield and Vortex 1-2(SAV1-2)for extracting spatial texture information from sun glit...Taking the advantage of sun glitter(SG)observed from high-resolution satellites Gaofen-1(GF-1)and Gaofen-6(GF-6),a new method named Shield and Vortex 1-2(SAV1-2)for extracting spatial texture information from sun glitter was established.Sea surface texture detail information around Diaoyu Dao and its affiliated islands was extracted using SAV1-2.Meanwhile,the dynamic characteristics of the water environment were analyzed by combining the water color,temperature and dynamic data.The results show the following information.(1)Stable westward shield effect and eastward Karman vortex streets,extracted from SG,appear upstream(westward)and downstream(eastward)of the Diaoyu Dao and its affiliated islands respectively.(2)The dominant direction of the Kuroshio Current in the Diaoyu Dao and its affiliated islands area is east,the Diaoyu Dao and its affiliated islands interacting with Kuroshio,inducing western shield and eastern shelter and wake.Furthermore,wave intervals of the shield in front of the island range from hundreds to thousands of metres,and extend wider than the island itself.(3)Combining with high-resolution sea surface temperature(SST)and chlorophyll a(Chl a)concentration,the directional changes of water color elements are mutually supported and proved with the stable shield(wave packet)effect in the west and vortex street effect in the east.The change of SST upstream of the island(western shield area)is not significant,the temperature in the downstream shelter area decreases slightly,and the SST in the downstream wake area shows a general trend of obvious decrease.The wake area is dominated by Karman vortex streets in shape,supplementing by vortices.The concentration of Chl a in the west shield of island is as low as that in downstream shelter area,while it increases significantly in the downstream wake area with shape in eddy or ribbon.(4)The SAV methods of extracting sea surface texture detail using SG can be widely used in different sea areas and water quality.This paper can provide reference for the protection and development of Diaoyu Dao and its affiliated islands and its surrounding waters.It is suggested that some kind of current buffer,such as marine wind farm,should be established in the western waters of Diaoyu Dao and its affiliated islands to protect the islands,and marine pasture should be developed in the downstream of eastern waters of Diaoyu Dao and its affiliated islands.展开更多
The induced airfl w from passing trains,which is recognized as train wind,usually has adverse impacts on people in the surroundings,i.e.,the aerodynamic forces generated by a high-speed train's wind may act on the hu...The induced airfl w from passing trains,which is recognized as train wind,usually has adverse impacts on people in the surroundings,i.e.,the aerodynamic forces generated by a high-speed train's wind may act on the human body and endanger the safety of pedestrians or roadside workers.In this paper,an improved delayed detached eddy simulation(IDDES) method is used to study train wind.The effects of the affiliate components and train length on train wind are analyzed.The results indicate that the aff liated components and train length have no effect on train wind in the area in front of the leading nose.In the downstream and wake regions,the longitudinal train wind becomes stronger as the length of the train increases,while the transverse train wind is not affected.The presence of affiliate components strengthens the train wind in the near fiel of the train because of strong fl w solid interactions but has limited effects on train wind in the far field.展开更多
With the rapid development of the technology of information network and the era of big data,information technology is now widely used in the field of education.Comprehensive popularity of mobile phones,computers,table...With the rapid development of the technology of information network and the era of big data,information technology is now widely used in the field of education.Comprehensive popularity of mobile phones,computers,tablet computers and portable communication devices and WIFI also facilitate the widespread use of online learning,learning in free time,free learning and other modes.The emergence of microlecture follows the learning mode and trend of modern society,special for young medical students who are highly passionate in accepting new things and have a strong ability in using information technology.In this paper,the necessity and feasibility of self-directed teaching methods related to microlecture and flipped classroom in the teaching in a non-directly affiliated hospital.Using the advantages of the"microlecture and flipped classroom"teaching model,it is possible to improve the learning effect of medical students,construct high-quality online courses,and make quality teaching resources widely shared.展开更多
In this paper,the development ofsatellite ground systems and non-satellite equipments and systems de-rived from satellite technology inthe Chinese Academy of SpaceTechnology is reviewed.Satelliteground systems include...In this paper,the development ofsatellite ground systems and non-satellite equipments and systems de-rived from satellite technology inthe Chinese Academy of SpaceTechnology is reviewed.Satelliteground systems include those fortracking,monitoring and controlfor the launch and operation ofsatellites as well as transmitting andreceiving system for dedicated andindividual users.Derived systemsand equipment include some ofspinoff from satellite technologies,such as computer measurement andcontrol,attitude control,thermalcontrol,radio electronic technique,vacuum technique and new materi-als.They are related to the eco-nomic and social benefits derivedfrom the development of space tech-nology.展开更多
In a symmetric affiliated value model, this paper analyses High-Technology industrial firms’ competitive strategy in research and development. (R&D). We obtain the symmetric Bayesian Nash Equilibrium functions wi...In a symmetric affiliated value model, this paper analyses High-Technology industrial firms’ competitive strategy in research and development. (R&D). We obtain the symmetric Bayesian Nash Equilibrium functions with or without government’s prize: b1(x)=v(x,)Fn-1 (y∣y), and b3(x)= . We find the firm’s investment level will increase in prize, only when the constant prize V0≥v(y,y) , does the firm invest more aggressively with constant prize than with variable prize. Key words affiliated value - Bayesian Nash solution - prize CLC number O 29 - F 224.3 Biography: Che Ka-jia (1954-), female, Ph. D candidate, research direction: financial mathematics and business administration.展开更多
The Hefei Branch of the CAS is an R&D base specializing in basic research and applied developmentof technological physics, established by the CAS in the area of Hefei City,capital of Anhui Province.It is situated ...The Hefei Branch of the CAS is an R&D base specializing in basic research and applied developmentof technological physics, established by the CAS in the area of Hefei City,capital of Anhui Province.It is situated beside the Dongpu Reservoir in the western suourb of the City’s downtown area,covering 186.7 hectares in total area. At present, the Branch consists of five subordinate unit.i.e.the Branch organ, the Anhui Institute of Optics & Fine Mechanics, the Institute of Plasma Physics, the Institute of Solid-state Physics and the Institule of Intel-展开更多
There are two inaccuracies to the common belief that hot money flows into China through international trade: "hot money" and "trade channels". First, China’s domestic financial market is still at ...There are two inaccuracies to the common belief that hot money flows into China through international trade: "hot money" and "trade channels". First, China’s domestic financial market is still at the initial stage of development, and foreign exchange control has put barriers to entry and exit of overseas capital. Strictly speaking, the short-term highly liquid "hot money" does not exist in China, and is referred to as long-term speculative capital in this paper. Second, such capital does not come from trade alone. International trade is only part of corporate business operations, and a more reasonable and complete description is that "overseas capital flows into China through foreign-funded enterprises". Through analysis of the inflow channels, this paper estimates that the stock of long-term speculative capital between 1999 and 2006 stands at almost US$ 400 billion. The year 2006 saw an increase of US$ 98.09 billion, of which US$ 35.4 billion was formed through international trade, which equals to roughly 20% of trade surplus that year. But this does not mean that 20% of trade surplus is long-term speculative capital.展开更多
Aim: The following work studied how tribal affiliation, educational level and occupation of some women that had PPH in Maiduguri metropolis between September 2007 and March 2009 relate with PPH occurrence. The study w...Aim: The following work studied how tribal affiliation, educational level and occupation of some women that had PPH in Maiduguri metropolis between September 2007 and March 2009 relate with PPH occurrence. The study was aimed at identifying possible risk factors and also to compare the relative prevention efficacies of oxytocin or misoprostol within the matrix of these factors. Method: A total of 1800 pregnant women who have received either oxytocin injection or oral misoprostol in third stage of labour as a prophylaxis of postpartum haemorrhage, were enrolled within three health care facilities in Maiduguri, Nigeria. Each patient was observed at parturition and for 24 h after, during which blood lost was estimated to the nearest millilitres. Demographic characteristics were recorded in a structured proforma. The relationship of the occurrence of PPH (occurrence of blood loss > 500 ml) and mean blood loss (MBL) was studied with respect to the prophylactic medication used and some demographic factors. Results: The incidence of PPH was higher in Igbo, and some “minority” tribes of Borno state (Babur, Bura, Mafa). The tribes that constituted the majority of the study population (Kanuri, and Hausa) exhibited low incidences of PPH. Significant relationships were demonstrated between PPH and educational levels and occupations of participants. Conclussions: It was concluded that PPH occurrence is related to tribal affiliation, educational level and occupation, and the relative efficacies of oxytocin and misoprostol varies between the tribal groups.展开更多
An understanding of the knowledge creation and diffusion process in the organizational context is extremely relevant. Because from this understanding, organizations can restructure processes, reorient teams and implem...An understanding of the knowledge creation and diffusion process in the organizational context is extremely relevant. Because from this understanding, organizations can restructure processes, reorient teams and implement methodologies to assist in the construction of an evolutionary process of knowledge creation and diffusion aimed at sustainable growth and innovation. The theory of complex social networks has been applied in several fields to help understand organizational cognitive processes. However, these approaches still insipiently consider the analysis of the nestedness and modularity of the studied networks. In this article, we presented an approach that sought to identify patterns of nestedness and modularity in networks of affiliation of people in projects in the organizational context. The study sought to identify these patterns in affiliation networks in a public organization providing information technology services in the period from 2006 to 2013. The detection of these patterns was performed using the NODF (Nestedness metric based on Overlap and Decreasing Fill) algorithm described by <a href="#ref1">[1]</a>. The nestedness and modularity metrics can influence patterns of knowledge creation and diffusion in formal and informal networks constituted for the execution of projects in organizations. This study showed that the network structures of the organization during the study period presented a high degree of nestedness, and it was possible to identify combined structures of nestedness and modularity.展开更多
This work presents an approach to study the diffusion of knowledge in software development project teams based on the formation of complex social network structures in a public organization that offers information and...This work presents an approach to study the diffusion of knowledge in software development project teams based on the formation of complex social network structures in a public organization that offers information and communication technology services. We collected historical data on the allocation and records of hours worked by people in projects to build an affiliation network. We applied the method of reflections to analyze the data obtained. The constructed model enabled the description of the participation of project team members from the perspective of the creation and diffusion of knowledge in affiliation networks that describe the participation of people in projects, mediated by the knowledge and the capabilities developed for the execution of these projects. A contribution of this work is the construction of indicators related to the process of creation and diffusion of knowledge in the context of the execution of software development and maintenance projects, based on the concepts of diversification and ubiquity applied to the process of knowledge diffusion;an additional contribution is the presentation of an application of the method of reflections in an organizational context applied to the creation and diffusion of knowledge. We found that the application of management models associated with the collaborative method applied to the project development process contributed to the joint growth of diversified and more specialized knowledge alongside the knowledge considered more generic and ubiquitous. Our results show that contrary </span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">to </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">previous expectations based on assumptions established at the beginning of the study, we concluded that in six of the seven subnetworks obtained in the period between 2007 and 2013, knowledge based on complex and diversified capabilities showed a growth proportional to the growth of knowledge related to the capabilities necessary to more general and ubiquitous activities.展开更多
ForewordIt is our honor and pleasure to welcome you to the 2nd Far Eastern Conference on Medicaland Biological Engineering (2nd FECMBE) in Beijing,China,1993.In 1987,Far Eastern Society of Biomedical Engineering(China...ForewordIt is our honor and pleasure to welcome you to the 2nd Far Eastern Conference on Medicaland Biological Engineering (2nd FECMBE) in Beijing,China,1993.In 1987,Far Eastern Society of Biomedical Engineering(China,Japan,Korea and Taipei,China) affiliated to展开更多
Jennifer S.Smith is an Associate Professor of Department of Epidemiology,Gillings School of Global Public Health,University of North Carolina.Dr.Smith is also affiliated with the UNC Lineberger Comprehensive Cancer Ce...Jennifer S.Smith is an Associate Professor of Department of Epidemiology,Gillings School of Global Public Health,University of North Carolina.Dr.Smith is also affiliated with the UNC Lineberger Comprehensive Cancer Center(Cancer Epidemiology),UNC Center for AIDS Research,and the UNC Center for Women’s Health Research.Dr.Smith has conducted research on HPV展开更多
The therapeutic effects of peptic ulcer treated with cimetidine and Wei Yang An (胃疡安) werecompared clinically and experimentally by the double blind method.Results showed that the ef-fects of the two are similar,bu...The therapeutic effects of peptic ulcer treated with cimetidine and Wei Yang An (胃疡安) werecompared clinically and experimentally by the double blind method.Results showed that the ef-fects of the two are similar,but the long-term effect of Wei Yang An was better.Wei Yang Anwas also good for most cimetidine resistant ulcers,with few side effect.Animal experiment show-ed that Wei Yang An inhibited the ulcers.展开更多
Fei Ai Chong Ji is a pure herbal prepa-ration to be taken after being infused in hotwater for the treatment of lung cancer. Thedevelopment of the preparation is based onthe TCM principle of strengthening thebody resis...Fei Ai Chong Ji is a pure herbal prepa-ration to be taken after being infused in hotwater for the treatment of lung cancer. Thedevelopment of the preparation is based onthe TCM principle of strengthening thebody resistance to eliminate pathogenic fac-tors and combining differentiation of symp-toms with discrimination of diseases. In re-展开更多
基金The Science Foundation of Donghai Laboratory under contract No.DH-2022KF01010the Zhejiang Key Science and Technology Project under contract No.2020C02004+1 种基金the Basic Public Welfare Research Program of Zhejiang Province under contract No.LGF21D010004the Research on Group Ideological and Political Subject Teaching Model of Ocean Remote Sensing under contract No.132.
文摘Taking the advantage of sun glitter(SG)observed from high-resolution satellites Gaofen-1(GF-1)and Gaofen-6(GF-6),a new method named Shield and Vortex 1-2(SAV1-2)for extracting spatial texture information from sun glitter was established.Sea surface texture detail information around Diaoyu Dao and its affiliated islands was extracted using SAV1-2.Meanwhile,the dynamic characteristics of the water environment were analyzed by combining the water color,temperature and dynamic data.The results show the following information.(1)Stable westward shield effect and eastward Karman vortex streets,extracted from SG,appear upstream(westward)and downstream(eastward)of the Diaoyu Dao and its affiliated islands respectively.(2)The dominant direction of the Kuroshio Current in the Diaoyu Dao and its affiliated islands area is east,the Diaoyu Dao and its affiliated islands interacting with Kuroshio,inducing western shield and eastern shelter and wake.Furthermore,wave intervals of the shield in front of the island range from hundreds to thousands of metres,and extend wider than the island itself.(3)Combining with high-resolution sea surface temperature(SST)and chlorophyll a(Chl a)concentration,the directional changes of water color elements are mutually supported and proved with the stable shield(wave packet)effect in the west and vortex street effect in the east.The change of SST upstream of the island(western shield area)is not significant,the temperature in the downstream shelter area decreases slightly,and the SST in the downstream wake area shows a general trend of obvious decrease.The wake area is dominated by Karman vortex streets in shape,supplementing by vortices.The concentration of Chl a in the west shield of island is as low as that in downstream shelter area,while it increases significantly in the downstream wake area with shape in eddy or ribbon.(4)The SAV methods of extracting sea surface texture detail using SG can be widely used in different sea areas and water quality.This paper can provide reference for the protection and development of Diaoyu Dao and its affiliated islands and its surrounding waters.It is suggested that some kind of current buffer,such as marine wind farm,should be established in the western waters of Diaoyu Dao and its affiliated islands to protect the islands,and marine pasture should be developed in the downstream of eastern waters of Diaoyu Dao and its affiliated islands.
文摘The induced airfl w from passing trains,which is recognized as train wind,usually has adverse impacts on people in the surroundings,i.e.,the aerodynamic forces generated by a high-speed train's wind may act on the human body and endanger the safety of pedestrians or roadside workers.In this paper,an improved delayed detached eddy simulation(IDDES) method is used to study train wind.The effects of the affiliate components and train length on train wind are analyzed.The results indicate that the aff liated components and train length have no effect on train wind in the area in front of the leading nose.In the downstream and wake regions,the longitudinal train wind becomes stronger as the length of the train increases,while the transverse train wind is not affected.The presence of affiliate components strengthens the train wind in the near fiel of the train because of strong fl w solid interactions but has limited effects on train wind in the far field.
基金This work was supported by the Weifang Medical College 2019 University-level Teaching Reform and Research Project(Grant No:2019ZXSJ029).
文摘With the rapid development of the technology of information network and the era of big data,information technology is now widely used in the field of education.Comprehensive popularity of mobile phones,computers,tablet computers and portable communication devices and WIFI also facilitate the widespread use of online learning,learning in free time,free learning and other modes.The emergence of microlecture follows the learning mode and trend of modern society,special for young medical students who are highly passionate in accepting new things and have a strong ability in using information technology.In this paper,the necessity and feasibility of self-directed teaching methods related to microlecture and flipped classroom in the teaching in a non-directly affiliated hospital.Using the advantages of the"microlecture and flipped classroom"teaching model,it is possible to improve the learning effect of medical students,construct high-quality online courses,and make quality teaching resources widely shared.
文摘In this paper,the development ofsatellite ground systems and non-satellite equipments and systems de-rived from satellite technology inthe Chinese Academy of SpaceTechnology is reviewed.Satelliteground systems include those fortracking,monitoring and controlfor the launch and operation ofsatellites as well as transmitting andreceiving system for dedicated andindividual users.Derived systemsand equipment include some ofspinoff from satellite technologies,such as computer measurement andcontrol,attitude control,thermalcontrol,radio electronic technique,vacuum technique and new materi-als.They are related to the eco-nomic and social benefits derivedfrom the development of space tech-nology.
文摘In a symmetric affiliated value model, this paper analyses High-Technology industrial firms’ competitive strategy in research and development. (R&D). We obtain the symmetric Bayesian Nash Equilibrium functions with or without government’s prize: b1(x)=v(x,)Fn-1 (y∣y), and b3(x)= . We find the firm’s investment level will increase in prize, only when the constant prize V0≥v(y,y) , does the firm invest more aggressively with constant prize than with variable prize. Key words affiliated value - Bayesian Nash solution - prize CLC number O 29 - F 224.3 Biography: Che Ka-jia (1954-), female, Ph. D candidate, research direction: financial mathematics and business administration.
文摘The Hefei Branch of the CAS is an R&D base specializing in basic research and applied developmentof technological physics, established by the CAS in the area of Hefei City,capital of Anhui Province.It is situated beside the Dongpu Reservoir in the western suourb of the City’s downtown area,covering 186.7 hectares in total area. At present, the Branch consists of five subordinate unit.i.e.the Branch organ, the Anhui Institute of Optics & Fine Mechanics, the Institute of Plasma Physics, the Institute of Solid-state Physics and the Institule of Intel-
文摘There are two inaccuracies to the common belief that hot money flows into China through international trade: "hot money" and "trade channels". First, China’s domestic financial market is still at the initial stage of development, and foreign exchange control has put barriers to entry and exit of overseas capital. Strictly speaking, the short-term highly liquid "hot money" does not exist in China, and is referred to as long-term speculative capital in this paper. Second, such capital does not come from trade alone. International trade is only part of corporate business operations, and a more reasonable and complete description is that "overseas capital flows into China through foreign-funded enterprises". Through analysis of the inflow channels, this paper estimates that the stock of long-term speculative capital between 1999 and 2006 stands at almost US$ 400 billion. The year 2006 saw an increase of US$ 98.09 billion, of which US$ 35.4 billion was formed through international trade, which equals to roughly 20% of trade surplus that year. But this does not mean that 20% of trade surplus is long-term speculative capital.
文摘Aim: The following work studied how tribal affiliation, educational level and occupation of some women that had PPH in Maiduguri metropolis between September 2007 and March 2009 relate with PPH occurrence. The study was aimed at identifying possible risk factors and also to compare the relative prevention efficacies of oxytocin or misoprostol within the matrix of these factors. Method: A total of 1800 pregnant women who have received either oxytocin injection or oral misoprostol in third stage of labour as a prophylaxis of postpartum haemorrhage, were enrolled within three health care facilities in Maiduguri, Nigeria. Each patient was observed at parturition and for 24 h after, during which blood lost was estimated to the nearest millilitres. Demographic characteristics were recorded in a structured proforma. The relationship of the occurrence of PPH (occurrence of blood loss > 500 ml) and mean blood loss (MBL) was studied with respect to the prophylactic medication used and some demographic factors. Results: The incidence of PPH was higher in Igbo, and some “minority” tribes of Borno state (Babur, Bura, Mafa). The tribes that constituted the majority of the study population (Kanuri, and Hausa) exhibited low incidences of PPH. Significant relationships were demonstrated between PPH and educational levels and occupations of participants. Conclussions: It was concluded that PPH occurrence is related to tribal affiliation, educational level and occupation, and the relative efficacies of oxytocin and misoprostol varies between the tribal groups.
文摘An understanding of the knowledge creation and diffusion process in the organizational context is extremely relevant. Because from this understanding, organizations can restructure processes, reorient teams and implement methodologies to assist in the construction of an evolutionary process of knowledge creation and diffusion aimed at sustainable growth and innovation. The theory of complex social networks has been applied in several fields to help understand organizational cognitive processes. However, these approaches still insipiently consider the analysis of the nestedness and modularity of the studied networks. In this article, we presented an approach that sought to identify patterns of nestedness and modularity in networks of affiliation of people in projects in the organizational context. The study sought to identify these patterns in affiliation networks in a public organization providing information technology services in the period from 2006 to 2013. The detection of these patterns was performed using the NODF (Nestedness metric based on Overlap and Decreasing Fill) algorithm described by <a href="#ref1">[1]</a>. The nestedness and modularity metrics can influence patterns of knowledge creation and diffusion in formal and informal networks constituted for the execution of projects in organizations. This study showed that the network structures of the organization during the study period presented a high degree of nestedness, and it was possible to identify combined structures of nestedness and modularity.
文摘This work presents an approach to study the diffusion of knowledge in software development project teams based on the formation of complex social network structures in a public organization that offers information and communication technology services. We collected historical data on the allocation and records of hours worked by people in projects to build an affiliation network. We applied the method of reflections to analyze the data obtained. The constructed model enabled the description of the participation of project team members from the perspective of the creation and diffusion of knowledge in affiliation networks that describe the participation of people in projects, mediated by the knowledge and the capabilities developed for the execution of these projects. A contribution of this work is the construction of indicators related to the process of creation and diffusion of knowledge in the context of the execution of software development and maintenance projects, based on the concepts of diversification and ubiquity applied to the process of knowledge diffusion;an additional contribution is the presentation of an application of the method of reflections in an organizational context applied to the creation and diffusion of knowledge. We found that the application of management models associated with the collaborative method applied to the project development process contributed to the joint growth of diversified and more specialized knowledge alongside the knowledge considered more generic and ubiquitous. Our results show that contrary </span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">to </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">previous expectations based on assumptions established at the beginning of the study, we concluded that in six of the seven subnetworks obtained in the period between 2007 and 2013, knowledge based on complex and diversified capabilities showed a growth proportional to the growth of knowledge related to the capabilities necessary to more general and ubiquitous activities.
文摘ForewordIt is our honor and pleasure to welcome you to the 2nd Far Eastern Conference on Medicaland Biological Engineering (2nd FECMBE) in Beijing,China,1993.In 1987,Far Eastern Society of Biomedical Engineering(China,Japan,Korea and Taipei,China) affiliated to
文摘Jennifer S.Smith is an Associate Professor of Department of Epidemiology,Gillings School of Global Public Health,University of North Carolina.Dr.Smith is also affiliated with the UNC Lineberger Comprehensive Cancer Center(Cancer Epidemiology),UNC Center for AIDS Research,and the UNC Center for Women’s Health Research.Dr.Smith has conducted research on HPV
文摘The therapeutic effects of peptic ulcer treated with cimetidine and Wei Yang An (胃疡安) werecompared clinically and experimentally by the double blind method.Results showed that the ef-fects of the two are similar,but the long-term effect of Wei Yang An was better.Wei Yang Anwas also good for most cimetidine resistant ulcers,with few side effect.Animal experiment show-ed that Wei Yang An inhibited the ulcers.
文摘Fei Ai Chong Ji is a pure herbal prepa-ration to be taken after being infused in hotwater for the treatment of lung cancer. Thedevelopment of the preparation is based onthe TCM principle of strengthening thebody resistance to eliminate pathogenic fac-tors and combining differentiation of symp-toms with discrimination of diseases. In re-