In order to analyze the spray characteristics of non-circular nozzle holes based on the air-assisted spray system, the spray characteristics of circular and non-circular nozzles were studied under the pressure of 0.2-...In order to analyze the spray characteristics of non-circular nozzle holes based on the air-assisted spray system, the spray characteristics of circular and non-circular nozzles were studied under the pressure of 0.2-0.6 MPa and the spray volume of 1000-5000 mL/h. Elliptical nozzle and triangular nozzle are classified as non-circular geometries. The spray cone angle was measured by processing the spray image captured by a CCD camera. The measured spray cone angles of the circular nozzles were analyzed, and the axis switching phenomenon of minor plane of elliptical nozzle was found during the test. Among the three shapes of nozzles, the elliptical nozzle had the largest spray cone angle, and the triangular nozzle had the smallest. The velocity field obtained depended on the PIV system. The results show that for axial velocity, elliptical orifice spray has greater kinetic energy and smaller droplet size under the same working parameters. Compared with the circular and elliptical nozzles, triangular orifice reached maximum spray velocity the fastest, but its velocity decay was the fastest. For radial velocity, away from the axis, the spray velocity of the elliptical orifice was less affected by the injection parameters, and the velocity was less than that of circular orifice and triangle orifice. Increasing air pressure will weaken radial propagation. The increase of liquid spraying rate had no remarkable effect on the increase of spraying rate. The results of particle size analysis show that the particle size of the non-circular orifice is reduced compared with that of the circular orifice, which promotes the breakup of droplets to a certain extent and enhances the atomization effect.展开更多
The nozzle inner-flow characteristic of the“spray G”injector was studied by the computational fluid dynamics(CFD)simulation,and the sensitivity of cycle fuel mass to the conicity and entrance radius of the nozzle ho...The nozzle inner-flow characteristic of the“spray G”injector was studied by the computational fluid dynamics(CFD)simulation,and the sensitivity of cycle fuel mass to the conicity and entrance radius of the nozzle hole were analyzed.Results show that the inner conicity of nozzle hole inhibits the development of cavitation phenomena,and increases the injection rate.While the outer conicity of nozzle hole promotes the diffusion of cavita-tion,leading to reductions of the liquid volume fraction of the nozzle outlet and the local flow resistance of the nozzle hole.The sensitivity of cycle fuel mass to inner-cone nozzle hole is stronger than that of the outer-cone noz-zle,especially at the smaller hole conicity.The increase of injection pressure enhances the sensitivity of the injection characteristics to the nozzle hole structure,in which inner-cone nozzle has higher sensitivity coefficient than the outer-cone nozzle hole.However,the increase of injection pressure aggravates the offset of liquid jet to the nozzle axis of the outer-cone nozzle hole.With the increase of the inner conicity of nozzle,the sensitivity of the injection characteristics to the entrance radius of the hole decreases.With the increase of the outer conicity of nozzle hole,the sensitivity of the injection characteristics to the entrance radius of the hole increases.展开更多
AIM: To explore the distribution and metabolism of 131 I-gelatin microspheres ( 131 I-GMSs) in rabbits after direct injection into rabbits’ livers.METHODS: Twenty-eight healthy New Zealand rabbits were divided into s...AIM: To explore the distribution and metabolism of 131 I-gelatin microspheres ( 131 I-GMSs) in rabbits after direct injection into rabbits’ livers.METHODS: Twenty-eight healthy New Zealand rabbits were divided into seven groups,with four rabbits per group.Each rabbit’s hepatic lobes were directly injected with 41.336 ± 5.106 MBq 131 I-GMSs.Each day after 131 I-GMSs administration,4 rabbits were randomly selected,and 250 μL of serum was collected for γ count.Hepatic and thyroid functions were tested on days 1,4,8,16,24,32,48 and 64 after 131 I-GMSs administration.Single-photon emission computed tomography (SPECT) was taken for each group on days 0,1,4,8,16,24,32,48,64 after 131 I-GMSs administration.A group of rabbits were sacrificed respectively on days 1,4,16,24,32,48,64 after 131 I-GMSs administration.Their livers were taken out for histological examination.RESULTS: After 131 I-GMSs administration,the nuclide was collected in the hepatic area with microspheres.The radiation could be detected on day 48 after 131 IGMSs administration,and radiography could be seen in thyroid areas in SPECT on days 4,8,16 and 24.One day after 131 I-GMSs administration,the liver function was damaged but recovered 4 d later.Eight days after 131 I-GMSs administration,the levels of free triiodothyronine and free thyroxin were reduced,which restored to normal levels on day 16.Histological examination showed that the microspheres were degraded to different degrees at 24,32 and 48 d after 131 I-GMSs administration.The surrounding parts of injection points were in fibrous sheathing.No microspheres were detected in histological examination on day 64 after 131 I-GMSs administration.CONCLUSION: Direct in vivo injection of 131 I-GMSs is safe in rabbits.It may be a promising method for treatment of malignant tumors.展开更多
To promote the modeling standardization process of the integrated circuits, an improved electrical simulation model for a direct power injection (DPI) setup which was used to measure the conducted immunity of a 16-b...To promote the modeling standardization process of the integrated circuits, an improved electrical simulation model for a direct power injection (DPI) setup which was used to measure the conducted immunity of a 16-bit microcontroller to radio frequency aggression was investigated. Based on the existing model of the same microcontroller, the PDN module was modified by adding the core, PLL and MD network models, which could reflect the actual electric distribution situation within the microcontroller more accurately. By comparing the simulation results with the measurement results, the effectiveness of the modified model can be improved to 500 MHz, and its uncertainty is within +1.8 dB (+2 dB is acceptable). Then, to improve the simulation accuracy of the complete model in the high frequency range, the I/O model which contained the dynamic and nonlinear characteristics reflecting the variation of the internal impedance of the microcontroller with increasing the frequency of the external noise was introduced. By comparing the simulation results with the measurement results, the effectiveness of the second modified model can be improved up to 1.4 GHz with the uncertainty of ~1.8 dB. Thus, a conclusion can be reached that the proposed model can be applied to a much wider frequency range with a smaller uncertainty than the latest model of the similar type. Furthermore, associated with the electromagnetic emission testing platform model, the PDN module can also be used to predict the electromagnetic conducted and radiated emission characteristics. This modeling method can also be applied to other integrated circuits, which is very helpful to the standardization of the IC electromagnetic compatibility (EMC) modeling process.展开更多
Aviation heavy-fuel spark ignition(SI)piston engines have been paid more and more attention in the area of small aviation.Aviation heavy-fuel refers to aviation kerosene or light diesel fuel,which is safer to use and ...Aviation heavy-fuel spark ignition(SI)piston engines have been paid more and more attention in the area of small aviation.Aviation heavy-fuel refers to aviation kerosene or light diesel fuel,which is safer to use and store compared to gasoline fuel.And diesel fuel is more suitable for small aviation application on land.In this study,numerical simulation was performed to evaluate the possibility of switching from gasoline direct injection spark ignition(DISI)to diesel DISI combustion.Diesel was injected into the cylinder by original DI system and ignited by spark.In the simulation,computational models were calibrated by test data from a DI engine.Based on the calibrated models,furthermore,the behavior of diesel DISI combustion was investigated.The results indicate that diesel DISI combustion is slower compared to gasoline,and the knock tendency of diesel in SI combustion is higher.For a diesel/air mixture with an equivalence ratio of 0.6 to 1.4,higher combustion pressure and faster burning rate occur when the equivalence ratios are 1.2 and 1.0,but the latter has a higher possibility of knock.In summary,the SI combustion of diesel fuel with a rich mixture can achieve better combustion performance in the engine.展开更多
Docetaxel is a member of taxan family of antineoplastic agents widely used in cancer chemotherapy. However, application of conventional chemotherapy with commercial formulation has been accompanied with matters of con...Docetaxel is a member of taxan family of antineoplastic agents widely used in cancer chemotherapy. However, application of conventional chemotherapy with commercial formulation has been accompanied with matters of concern regarding drug’s biodistribution, pharmacokinetics, and pharmacodynamics. Polymeric nanoparticles have been widely used as unique drug delivery vehicles to circumvent such problems. Docetaxel-loaded poly (lactide-co-glycolide) (PLGA) and poly (lactide-co-glycolide)-poly (ethylene glycol) (PLGA-PEG) nanoparticles fit well in modifying drug’s pharmacokinetic characteristics as intravenous (IV) sustained-release delivery vehicles. In such circumstances, characterization of nanoparticles in terms of their drug-payload would be a necessary step. The majority of studies have used HPLC analysis method for docetaxel quantitation in polymeric nanoparticles. Herein, a rapid ESI-MS/MS method for quantitative analysis of docetaxel in polymeric matrices of PLGA and PLGA-PEG nanoparticles through direct injection to mass spectrometer has been developed and validated. The assay was validated over a range of 3.9 - 1000 ng/ml and 125 - 16,000 ng/ml. Samples were directly injected to the instrument through an isocratic elution (0.1% formic acid in methanol) and detection was performed on a Hybrid Triple Quadrupole/Linear Ion trap mass spectrometer with multiple reaction monitoring (MRM) mode via positive electrospray ionization (ESI) source. The run time and retention time were 2 and 0.6 minutes respectively. The method demonstrated acceptable level of accuracy and precision and was successfully applied for quantitative analysis of docetaxel in polymeric nanoparticles of PLGA and PLGA-PEG.展开更多
Background: Vitiligo is a common autoimmune inflammatory skin disease, where there are different surgical techniques for treatment of stable patches of vitiligo .Objective: To find non-costly, minimally invasive, simp...Background: Vitiligo is a common autoimmune inflammatory skin disease, where there are different surgical techniques for treatment of stable patches of vitiligo .Objective: To find non-costly, minimally invasive, simple technique by direct melanocytes transplant by spade needle technique in treatment of vitiligo. Patients and Methods: This interventional, therapeutic, comparative study was done in Department of Dermatology, Baghdad Teaching Hospital, Baghdad, Iraq from April 2014-March 2015. Twenty patients with localized, generalized and segmental vitiligo were included. Full history and examination for each patient was done with 4 (20%) males and 16 (80%) females and their ages ranged from 9 - 40 (23.15 ± 11.44) years. Forty one patches in 20 patients treated by spade grafting technique and the donor and recipient sites were demarcated and anesthesia done by xylocaine 2% with adrenalin 1:100,000. Transplantation was started by using disposable needle gauge 18 (the sharp end of needle was cut by a scissor to make it a spade like) with medical syringe 5 ml supplied with normal saline. The micro-pieces were taken from donor site and transplanted directly, easily and rapidly into dermis of recipient site and followed by pushing normal saline and the procedure was repeated to cover all recipient sites with 5 mm distance between injection points. The surface area of the lesions was calculated and the reduction rate was estimated every month till the end of the 4th month period of the treatment. Results: Including 41 patches in 20 patients with the surface area of the patches ranged from 1.5 - 90 cm<sup>2</sup> (13.78 ± 17.57) cm<sup>2</sup>. The mean ±SD of surface area of lesions was decreased from 13.78 ± 17.57 cm<sup>2</sup> at baseline visit to 13.61 ± 17.48 cm<sup>2</sup> at the second visit (after 2 weeks ) which was statistically significant (p value ≤ 0.001). The mean surface area continued to be reduced till reaching 12.20 ± 15.68 cm<sup>2</sup> at the third visit and 12.01 ± 15.55 cm<sup>2</sup> at the fourth visit. All were statistically significant when compared to baseline visit. There was reduction in surface area 1.1% at two weeks, 9.93%, and 12.5% at the 2nd, 4th months respectively. Conclusions: Intradermal injection of melanocytes in patients with vitiligo by spade like needle was very quick and simple non-costly technique, and gave 12.5% reduction which could be repeated at different times until satisfactory re-pigmentation of vitiligenous skin is achieved.展开更多
The use of ethanol is a promising method to reduce the emissions of diesel engines.The present study has been based on the installation of a gasoline electronic injection system in a single-cylinder diesel engine to c...The use of ethanol is a promising method to reduce the emissions of diesel engines.The present study has been based on the installation of a gasoline electronic injection system in a single-cylinder diesel engine to control the amount of ethanol entering the cylinder during the compression(while diesel has been injected into the cylinder by the original pump injection system).The injection time has been controlled by crank angle signal collected by an AVL angle indicator.In the tests ethanol and diesel each accounted for half of the fuel volume,and the total heat energy supply of the fuel was equivalent to that of the diesel under the operating conditions of the original engine.A three-dimensional combustion model of the diesel engine has been implemented by using the CFD software FIRE.Simulations have been carried out assuming uniform and non-uniform injections rate for the different holes and the different results have been compared.According to these results,a non-uniform injection rate can produce early ignition and cause an increase in the maximum in-cylinder pressure and the maximum average incylinder temperature.Moreover,in such conditions NO emissions are larger while soot emission is slightly lower.展开更多
Separation was reported by Dunn, Hankins and Ghowsi for the case that ions incapillary electrophoresis move opposite to electroosmosis and ions move faster than flow finally they get separated and reach the detector. ...Separation was reported by Dunn, Hankins and Ghowsi for the case that ions incapillary electrophoresis move opposite to electroosmosis and ions move faster than flow finally they get separated and reach the detector. Similar mode for electrokinetic chromatography is reported for p-xylene and toluene separation, which is called reverse direction MECC (micellar electrokinetic capillary chromatography). The effect of injection time on separation in reverse direction micellar electrokinetic capillary chromatography is investigated. In this study, hydrostatic and diffusion injection were studied.展开更多
A set of compressed natural gas (CNG) multi-point direct injection system of spark-ignited engines and the corresponding measurement and data acquisition systems were developed in this paper. Based on different inject...A set of compressed natural gas (CNG) multi-point direct injection system of spark-ignited engines and the corresponding measurement and data acquisition systems were developed in this paper. Based on different injection modes, the mixture formation and combustion of CNG low-pressure direct injection (LPDI) engines were studied under varying factors such as air/ fuel ratio, injection timing. Meanwhile, three-dimensional simulations were adopted to explain the mixture formation mechanisms of CNG low-pressure compound direct injection (LPCDI) mode. On the basis of test results and simulation of the mixture homogeneous degree, the conception of injection window was proposed, and the LPCDI mode was proved to be more beneficial to the mixture concentration stratification formation in cylinder under lean-burning conditions, which resulted in effective combustion and stability.展开更多
This paper deals with the application of two different injection strategies in a natural gas direct injection spark ignition single-cylinder engine model. The analysis includes the air flow characterization during com...This paper deals with the application of two different injection strategies in a natural gas direct injection spark ignition single-cylinder engine model. The analysis includes the air flow characterization during compression stroke and also the charge stratification. Two different swirl ratios are applied and piston bowl effects are analyzed during the gas jet deflection towards the spark plug. Achieving wall-guided effect, consequently, the charge stratification in spark plug region is obtained. The goal is to study the mixture formation differences for a single and a bi pulsed CNG (compressed natural gas) injection profiles and check the evolution of the methane concentration at the spark plug at the start of combustion.展开更多
The population which could not access to electricity was around 1.2 billion in 2010 and is distributed in many low developing countries. With the increase in the population and the economic growth in those countries, ...The population which could not access to electricity was around 1.2 billion in 2010 and is distributed in many low developing countries. With the increase in the population and the economic growth in those countries, waste generation is growing rapid especially for the organic and the plastic, and the uncontrolled waste disposal is becoming more serious issues to manage it. The interest on waste to energy is growing by the above drivers. This research was carried out for aiming to the real world adaption at the minimum cost of the pyrolysis oil from waste biomass in a diesel engine, mainly for electricity generation. The proposal of the appropriate adaptable blend ratio was the major scope rather than the optimization of the engine parameters. For the sake of it, the pyrolysis oil of the waste biomass was produced from a gasification pilot plant in Japan and blended with biodiesel at minimum effort. A small single cylinder diesel engine (direct injection) was used for the experiment with regard to full load power-output, exhaust emissions and fuel consumption.展开更多
Based on the analysis of the advantages of the Natural Gas Engine with Direct Injection (NGEDI) and the state of the art of the research in this area, the authors point out that, the NGEDI with high pressure is one ...Based on the analysis of the advantages of the Natural Gas Engine with Direct Injection (NGEDI) and the state of the art of the research in this area, the authors point out that, the NGEDI with high pressure is one potential selection and will have a good application prospects. Through investigation experiment and simulation results, the key techniques are put foreword for deployment of the NGEDI and some solutions are given.展开更多
The effects of different flow forms on an opposed-piston two-stroke(OPTS)gasoline-directinjection(GDI)engine was studied by analyzing the mixture formation and combustion.Swirl was broken and dissipated gradually ...The effects of different flow forms on an opposed-piston two-stroke(OPTS)gasoline-directinjection(GDI)engine was studied by analyzing the mixture formation and combustion.Swirl was broken and dissipated gradually and the turbulence kinetic energy(TKE)was small in the compression process;however,tumble was strengthened and the TKE was strong in the compression process.For swirl around X axis(the axis of cylinder)and tumble around Y axis(the vertical direction of injector),droplets were attached to the cylinder liner by the centrifugal force and the mixture distribution was poor.For tumble around Zaxis(the direction of injector),the wall film in cylinder liner was thin and mixture distribution was homogeneous.Results showed that since the injector were installed on the wall of the cylinder liner in the OPTS-GDI engine,the spray angle was small and the mixture formation time was short.The 45° oblique axis tumble ratio of 1 was reasonable for the mixture formation and combustion for an OPTS-GDI engine.展开更多
In order to improve the fuel consumption and exhaust emission for gasoline engines,gasoline direct injection(GDI) system is spotlighted to solve these requirements.Thus,many researchers focus on the investigation of...In order to improve the fuel consumption and exhaust emission for gasoline engines,gasoline direct injection(GDI) system is spotlighted to solve these requirements.Thus,many researchers focus on the investigation of spray characteristics and the fuel formation of GDI injector.This paper presents a complete numerical and experimental characterization of transient gasoline spray from a high pressure injection system equipped with a modern single-hole electric controlled injector in a pressurized constant volume vessel.The numerical analysis is carried out in a one-dimensional model of fuel injection system which is developed in the AVL HYDSIM environment.The experimental analyses are implemented through a self-developed injection rate measurement device and spray evolution visualization system.The experimental results of injection rate and spray dynamics are taken to tune and validate the built model.The visualization system synchronize a high speed CMOS camera to obtain the spray structure,moreover,the captured images are taken to validate the injector needle lift process which is simulated in the model.The reliability of the built model is demonstrated by comparing the numerical results with the experimental data.The formed vortex structure at 0.8 ms is effectively disintegrated at 6.2 ms and the spray dynamics become rather chaotic.The fuel flow characteristics within injector nozzle extremely influence the subsequent spray evolution,and therefore this point should be reconsidered when building hybrid breakup GDI spray model.The spray tip speed reach the maximum at 1.18 ms regardless of the operation conditions and this is only determined by the injector itself.Furthermore,an empirical equation for the spray tip penetration is obtained and good agreement with the measured results is reached at a certain extent.This paper provides a methodology for the investigation of spray behavior and fuel distribution of GDI engine design.展开更多
In order to investigate the effects of fuel injection distribution on the scrarnjet combustor performance, there are conducted three sets of test on a hydrocarbon fueled direct-connect scramjet test facility. The resu...In order to investigate the effects of fuel injection distribution on the scrarnjet combustor performance, there are conducted three sets of test on a hydrocarbon fueled direct-connect scramjet test facility. The results of Test A, whose fuel injection is carried out with injectors located on the top-wall and the bottom-wall, show that the fuel injection with an appropriate close-front and centralized distribution would be of much help to optimize combustor performances. The results of Test B, whose fuel injection is performed at the optimal injection locations found in Test A, with a given equivalence ratio and different injection proportions for each injector, show that this injection mode is of little benefit to improve combustor performances. The results of Test C with a circumferential fuel injection distribution displaies the possibility of ameliorating combustor performance. By analyzing the effects of injection location parameters on combustor performances on the base of the data of Test C, it is clear that the injector location has strong coupled influences on combustor performances. In addition, an irmer-force synthesis specific impulse is used to reduce the errors caused by the disturbance of fuel supply and working state of air heater while assessing combustor performances.展开更多
To achieve the electric field strength and the induced currents in equivalence in susceptibility tests with the high-level field radiation above 400 MHz,a double differential-mode(DM) current injection method based on...To achieve the electric field strength and the induced currents in equivalence in susceptibility tests with the high-level field radiation above 400 MHz,a double differential-mode(DM) current injection method based on directional couplers is proposed.Two cascaded symmetrical directional couplers compose a coupling device to inject the DM currents.When the coupling device is used,two devices are necessary to achieve the equivalence between radiation and injection,i.e.the equivalence between the injected voltages and the field strength,which is linear,regardless of the characteristics of the equipment under test(EUT).The results are verified by experiments using typical coaxial cables and nonlinear devices,where the equivalence between the nonlinear EUT responses induced by radiation and injection at both ends is achieved by using two coupling devices.At a frequency up to 1.75 GHz,the maximal experimental error is only 3.39%.The experimental results confirm the accuracy of the proposed method even both the EUTs work in the nonlinear region.The proposed method is applicable for radiated susceptibility(RS) testing of interconnected systems in the microwave frequency band.展开更多
Concerns about environmental pollution and energy shortages have increased worldwide. One approach to reduce CO2 emissions from gasoline engines is to achieve stratified charge combustion with various injection ratios...Concerns about environmental pollution and energy shortages have increased worldwide. One approach to reduce CO2 emissions from gasoline engines is to achieve stratified charge combustion with various injection ratios using port fuel injection (PFI) and direct injection. The combustion and emission characteristics of a 4-valve direct injection spark ignition (DISI) engine equipped with a dual injection system were investigated while the injection ratio was varied. When the direct injection ratio increased, the lean limit A/F was extended. This suggests that the dual injection gasoline engine with both PFI and direct injection can meet severe vehicle emission and fuel economy requirements. The dual injection system had higher combustion pressure than that of either a conventional or direct injection systems. Therefore, the engine power of a dual injection DISI engine would be higher than that of a single injection DISI engine. However, NOx emissions increased compared with the emission levels in both PFI and DISI systems.展开更多
In order to study the hypotonic and rheological particularity of “three soft” coal seam in west Henan, China, this paper explored the stress and damage characteristics of crack in coal under condition of water injec...In order to study the hypotonic and rheological particularity of “three soft” coal seam in west Henan, China, this paper explored the stress and damage characteristics of crack in coal under condition of water injection fracturing based on ABAQUS platform;The cohesive element in T-P damage evolution criterion was used to describe the approximately linear relationship between crack width and extending distance in soft coal. The simulation results show that stress evolution and crack damage in soft coal is a gradually developing process under condition of water injection fracturing. When the static pressure is 4 - 10 MPa, and the injection time is about 1 - 2 hours, the damage range of crack in soft coal can basically reach an ideal data of 80 - 100 m, and then greatly improve the hypotonic performance of “three soft” coal seam.展开更多
Natural fractures are generally well developed in most hydrocarbon and geothermal reservoirs,which can produce complex fracture networks due to the activation of fractures during hydraulic stimulation.The present pape...Natural fractures are generally well developed in most hydrocarbon and geothermal reservoirs,which can produce complex fracture networks due to the activation of fractures during hydraulic stimulation.The present paper is devoted to developing a method to investigate the activation characteristics of fracture under injection-shearing coupled condition at laboratory scale.The fluid is injected into the single-fractured granite until the fracture is activated based on the triaxial direct shear tests.The results show that injection process can significantly influence the shear stress distribution field,resulting in release of shear stress and relative slip between the opposite sides of the fractured surface.The injectioninduced activation of fracture is strongly dependent on the stress states.When the normal stress increases,the injection-induced activation pressure increases,and the comparatively high normal stress can restrain the fracture activation.The fracture deformation mechanisms during fluid injection are also discussed preliminarily with the experimental data.The sensitivity of shear stress to fluid injection increases with increase of shear stress level,while it decreases under high normal stress.The results can facilitate our understanding of the natural fracture activation behavior during fluid pressure stimulation.展开更多
基金Sponsored by the National Key R&D Project(Grant No.2019YFD1002500)the Key Projects of Science and Technology Support Plan of JiangsuP rovince(Grant No.BE2016341)the Open Fund of State Key Laboratory of Internal Combustion Engine(Grant No.GKF2015-004)。
文摘In order to analyze the spray characteristics of non-circular nozzle holes based on the air-assisted spray system, the spray characteristics of circular and non-circular nozzles were studied under the pressure of 0.2-0.6 MPa and the spray volume of 1000-5000 mL/h. Elliptical nozzle and triangular nozzle are classified as non-circular geometries. The spray cone angle was measured by processing the spray image captured by a CCD camera. The measured spray cone angles of the circular nozzles were analyzed, and the axis switching phenomenon of minor plane of elliptical nozzle was found during the test. Among the three shapes of nozzles, the elliptical nozzle had the largest spray cone angle, and the triangular nozzle had the smallest. The velocity field obtained depended on the PIV system. The results show that for axial velocity, elliptical orifice spray has greater kinetic energy and smaller droplet size under the same working parameters. Compared with the circular and elliptical nozzles, triangular orifice reached maximum spray velocity the fastest, but its velocity decay was the fastest. For radial velocity, away from the axis, the spray velocity of the elliptical orifice was less affected by the injection parameters, and the velocity was less than that of circular orifice and triangle orifice. Increasing air pressure will weaken radial propagation. The increase of liquid spraying rate had no remarkable effect on the increase of spraying rate. The results of particle size analysis show that the particle size of the non-circular orifice is reduced compared with that of the circular orifice, which promotes the breakup of droplets to a certain extent and enhances the atomization effect.
文摘The nozzle inner-flow characteristic of the“spray G”injector was studied by the computational fluid dynamics(CFD)simulation,and the sensitivity of cycle fuel mass to the conicity and entrance radius of the nozzle hole were analyzed.Results show that the inner conicity of nozzle hole inhibits the development of cavitation phenomena,and increases the injection rate.While the outer conicity of nozzle hole promotes the diffusion of cavita-tion,leading to reductions of the liquid volume fraction of the nozzle outlet and the local flow resistance of the nozzle hole.The sensitivity of cycle fuel mass to inner-cone nozzle hole is stronger than that of the outer-cone noz-zle,especially at the smaller hole conicity.The increase of injection pressure enhances the sensitivity of the injection characteristics to the nozzle hole structure,in which inner-cone nozzle has higher sensitivity coefficient than the outer-cone nozzle hole.However,the increase of injection pressure aggravates the offset of liquid jet to the nozzle axis of the outer-cone nozzle hole.With the increase of the inner conicity of nozzle,the sensitivity of the injection characteristics to the entrance radius of the hole decreases.With the increase of the outer conicity of nozzle hole,the sensitivity of the injection characteristics to the entrance radius of the hole increases.
基金Supported by Grant from the Science & Technology Pillar Program of Sichuan Province,China,No.2009SZ184
文摘AIM: To explore the distribution and metabolism of 131 I-gelatin microspheres ( 131 I-GMSs) in rabbits after direct injection into rabbits’ livers.METHODS: Twenty-eight healthy New Zealand rabbits were divided into seven groups,with four rabbits per group.Each rabbit’s hepatic lobes were directly injected with 41.336 ± 5.106 MBq 131 I-GMSs.Each day after 131 I-GMSs administration,4 rabbits were randomly selected,and 250 μL of serum was collected for γ count.Hepatic and thyroid functions were tested on days 1,4,8,16,24,32,48 and 64 after 131 I-GMSs administration.Single-photon emission computed tomography (SPECT) was taken for each group on days 0,1,4,8,16,24,32,48,64 after 131 I-GMSs administration.A group of rabbits were sacrificed respectively on days 1,4,16,24,32,48,64 after 131 I-GMSs administration.Their livers were taken out for histological examination.RESULTS: After 131 I-GMSs administration,the nuclide was collected in the hepatic area with microspheres.The radiation could be detected on day 48 after 131 IGMSs administration,and radiography could be seen in thyroid areas in SPECT on days 4,8,16 and 24.One day after 131 I-GMSs administration,the liver function was damaged but recovered 4 d later.Eight days after 131 I-GMSs administration,the levels of free triiodothyronine and free thyroxin were reduced,which restored to normal levels on day 16.Histological examination showed that the microspheres were degraded to different degrees at 24,32 and 48 d after 131 I-GMSs administration.The surrounding parts of injection points were in fibrous sheathing.No microspheres were detected in histological examination on day 64 after 131 I-GMSs administration.CONCLUSION: Direct in vivo injection of 131 I-GMSs is safe in rabbits.It may be a promising method for treatment of malignant tumors.
基金Project(2007dfa71250) supported by the International Science and Technology Cooperative Program of ChinaProject(20062250) supported by the Doctor Fund of North China Electric Power University, China
文摘To promote the modeling standardization process of the integrated circuits, an improved electrical simulation model for a direct power injection (DPI) setup which was used to measure the conducted immunity of a 16-bit microcontroller to radio frequency aggression was investigated. Based on the existing model of the same microcontroller, the PDN module was modified by adding the core, PLL and MD network models, which could reflect the actual electric distribution situation within the microcontroller more accurately. By comparing the simulation results with the measurement results, the effectiveness of the modified model can be improved to 500 MHz, and its uncertainty is within +1.8 dB (+2 dB is acceptable). Then, to improve the simulation accuracy of the complete model in the high frequency range, the I/O model which contained the dynamic and nonlinear characteristics reflecting the variation of the internal impedance of the microcontroller with increasing the frequency of the external noise was introduced. By comparing the simulation results with the measurement results, the effectiveness of the second modified model can be improved up to 1.4 GHz with the uncertainty of ~1.8 dB. Thus, a conclusion can be reached that the proposed model can be applied to a much wider frequency range with a smaller uncertainty than the latest model of the similar type. Furthermore, associated with the electromagnetic emission testing platform model, the PDN module can also be used to predict the electromagnetic conducted and radiated emission characteristics. This modeling method can also be applied to other integrated circuits, which is very helpful to the standardization of the IC electromagnetic compatibility (EMC) modeling process.
基金Project(2018JJ2041)supported by the Science and Technology Project in Hunan Province,ChinaProject(szjj2019-008)supported by the Open Research Subject of Key Laboratory of Fluid and Power Machinery,Ministry of Education,China。
文摘Aviation heavy-fuel spark ignition(SI)piston engines have been paid more and more attention in the area of small aviation.Aviation heavy-fuel refers to aviation kerosene or light diesel fuel,which is safer to use and store compared to gasoline fuel.And diesel fuel is more suitable for small aviation application on land.In this study,numerical simulation was performed to evaluate the possibility of switching from gasoline direct injection spark ignition(DISI)to diesel DISI combustion.Diesel was injected into the cylinder by original DI system and ignited by spark.In the simulation,computational models were calibrated by test data from a DI engine.Based on the calibrated models,furthermore,the behavior of diesel DISI combustion was investigated.The results indicate that diesel DISI combustion is slower compared to gasoline,and the knock tendency of diesel in SI combustion is higher.For a diesel/air mixture with an equivalence ratio of 0.6 to 1.4,higher combustion pressure and faster burning rate occur when the equivalence ratios are 1.2 and 1.0,but the latter has a higher possibility of knock.In summary,the SI combustion of diesel fuel with a rich mixture can achieve better combustion performance in the engine.
文摘Docetaxel is a member of taxan family of antineoplastic agents widely used in cancer chemotherapy. However, application of conventional chemotherapy with commercial formulation has been accompanied with matters of concern regarding drug’s biodistribution, pharmacokinetics, and pharmacodynamics. Polymeric nanoparticles have been widely used as unique drug delivery vehicles to circumvent such problems. Docetaxel-loaded poly (lactide-co-glycolide) (PLGA) and poly (lactide-co-glycolide)-poly (ethylene glycol) (PLGA-PEG) nanoparticles fit well in modifying drug’s pharmacokinetic characteristics as intravenous (IV) sustained-release delivery vehicles. In such circumstances, characterization of nanoparticles in terms of their drug-payload would be a necessary step. The majority of studies have used HPLC analysis method for docetaxel quantitation in polymeric nanoparticles. Herein, a rapid ESI-MS/MS method for quantitative analysis of docetaxel in polymeric matrices of PLGA and PLGA-PEG nanoparticles through direct injection to mass spectrometer has been developed and validated. The assay was validated over a range of 3.9 - 1000 ng/ml and 125 - 16,000 ng/ml. Samples were directly injected to the instrument through an isocratic elution (0.1% formic acid in methanol) and detection was performed on a Hybrid Triple Quadrupole/Linear Ion trap mass spectrometer with multiple reaction monitoring (MRM) mode via positive electrospray ionization (ESI) source. The run time and retention time were 2 and 0.6 minutes respectively. The method demonstrated acceptable level of accuracy and precision and was successfully applied for quantitative analysis of docetaxel in polymeric nanoparticles of PLGA and PLGA-PEG.
文摘Background: Vitiligo is a common autoimmune inflammatory skin disease, where there are different surgical techniques for treatment of stable patches of vitiligo .Objective: To find non-costly, minimally invasive, simple technique by direct melanocytes transplant by spade needle technique in treatment of vitiligo. Patients and Methods: This interventional, therapeutic, comparative study was done in Department of Dermatology, Baghdad Teaching Hospital, Baghdad, Iraq from April 2014-March 2015. Twenty patients with localized, generalized and segmental vitiligo were included. Full history and examination for each patient was done with 4 (20%) males and 16 (80%) females and their ages ranged from 9 - 40 (23.15 ± 11.44) years. Forty one patches in 20 patients treated by spade grafting technique and the donor and recipient sites were demarcated and anesthesia done by xylocaine 2% with adrenalin 1:100,000. Transplantation was started by using disposable needle gauge 18 (the sharp end of needle was cut by a scissor to make it a spade like) with medical syringe 5 ml supplied with normal saline. The micro-pieces were taken from donor site and transplanted directly, easily and rapidly into dermis of recipient site and followed by pushing normal saline and the procedure was repeated to cover all recipient sites with 5 mm distance between injection points. The surface area of the lesions was calculated and the reduction rate was estimated every month till the end of the 4th month period of the treatment. Results: Including 41 patches in 20 patients with the surface area of the patches ranged from 1.5 - 90 cm<sup>2</sup> (13.78 ± 17.57) cm<sup>2</sup>. The mean ±SD of surface area of lesions was decreased from 13.78 ± 17.57 cm<sup>2</sup> at baseline visit to 13.61 ± 17.48 cm<sup>2</sup> at the second visit (after 2 weeks ) which was statistically significant (p value ≤ 0.001). The mean surface area continued to be reduced till reaching 12.20 ± 15.68 cm<sup>2</sup> at the third visit and 12.01 ± 15.55 cm<sup>2</sup> at the fourth visit. All were statistically significant when compared to baseline visit. There was reduction in surface area 1.1% at two weeks, 9.93%, and 12.5% at the 2nd, 4th months respectively. Conclusions: Intradermal injection of melanocytes in patients with vitiligo by spade like needle was very quick and simple non-costly technique, and gave 12.5% reduction which could be repeated at different times until satisfactory re-pigmentation of vitiligenous skin is achieved.
基金the National Natural Science Foundation of China(Nos.51476072 and 51366002)the Science and Technology Foundation of Guizhou Province(No.[2018]1006)+1 种基金Supporting Program for Top Scientific and Technological Talents in Universities of Guizhou Province(No.[2018]062)High-level Talent Research Funding Project of Guizhou Institute of Technology and Key Construction Projects of the First Class University(Phase I)of Guizhou Province in 2017-the First Class Course(Nos.2017158418 and 2017158435).
文摘The use of ethanol is a promising method to reduce the emissions of diesel engines.The present study has been based on the installation of a gasoline electronic injection system in a single-cylinder diesel engine to control the amount of ethanol entering the cylinder during the compression(while diesel has been injected into the cylinder by the original pump injection system).The injection time has been controlled by crank angle signal collected by an AVL angle indicator.In the tests ethanol and diesel each accounted for half of the fuel volume,and the total heat energy supply of the fuel was equivalent to that of the diesel under the operating conditions of the original engine.A three-dimensional combustion model of the diesel engine has been implemented by using the CFD software FIRE.Simulations have been carried out assuming uniform and non-uniform injections rate for the different holes and the different results have been compared.According to these results,a non-uniform injection rate can produce early ignition and cause an increase in the maximum in-cylinder pressure and the maximum average incylinder temperature.Moreover,in such conditions NO emissions are larger while soot emission is slightly lower.
文摘Separation was reported by Dunn, Hankins and Ghowsi for the case that ions incapillary electrophoresis move opposite to electroosmosis and ions move faster than flow finally they get separated and reach the detector. Similar mode for electrokinetic chromatography is reported for p-xylene and toluene separation, which is called reverse direction MECC (micellar electrokinetic capillary chromatography). The effect of injection time on separation in reverse direction micellar electrokinetic capillary chromatography is investigated. In this study, hydrostatic and diffusion injection were studied.
基金Supported by National High Technology Research and Development Program ("863" Program) of China (No.2008AA11A114)
文摘A set of compressed natural gas (CNG) multi-point direct injection system of spark-ignited engines and the corresponding measurement and data acquisition systems were developed in this paper. Based on different injection modes, the mixture formation and combustion of CNG low-pressure direct injection (LPDI) engines were studied under varying factors such as air/ fuel ratio, injection timing. Meanwhile, three-dimensional simulations were adopted to explain the mixture formation mechanisms of CNG low-pressure compound direct injection (LPCDI) mode. On the basis of test results and simulation of the mixture homogeneous degree, the conception of injection window was proposed, and the LPCDI mode was proved to be more beneficial to the mixture concentration stratification formation in cylinder under lean-burning conditions, which resulted in effective combustion and stability.
文摘This paper deals with the application of two different injection strategies in a natural gas direct injection spark ignition single-cylinder engine model. The analysis includes the air flow characterization during compression stroke and also the charge stratification. Two different swirl ratios are applied and piston bowl effects are analyzed during the gas jet deflection towards the spark plug. Achieving wall-guided effect, consequently, the charge stratification in spark plug region is obtained. The goal is to study the mixture formation differences for a single and a bi pulsed CNG (compressed natural gas) injection profiles and check the evolution of the methane concentration at the spark plug at the start of combustion.
文摘The population which could not access to electricity was around 1.2 billion in 2010 and is distributed in many low developing countries. With the increase in the population and the economic growth in those countries, waste generation is growing rapid especially for the organic and the plastic, and the uncontrolled waste disposal is becoming more serious issues to manage it. The interest on waste to energy is growing by the above drivers. This research was carried out for aiming to the real world adaption at the minimum cost of the pyrolysis oil from waste biomass in a diesel engine, mainly for electricity generation. The proposal of the appropriate adaptable blend ratio was the major scope rather than the optimization of the engine parameters. For the sake of it, the pyrolysis oil of the waste biomass was produced from a gasification pilot plant in Japan and blended with biodiesel at minimum effort. A small single cylinder diesel engine (direct injection) was used for the experiment with regard to full load power-output, exhaust emissions and fuel consumption.
文摘Based on the analysis of the advantages of the Natural Gas Engine with Direct Injection (NGEDI) and the state of the art of the research in this area, the authors point out that, the NGEDI with high pressure is one potential selection and will have a good application prospects. Through investigation experiment and simulation results, the key techniques are put foreword for deployment of the NGEDI and some solutions are given.
基金Supported by the National Natural Science Foundation of China(B2220110005)
文摘The effects of different flow forms on an opposed-piston two-stroke(OPTS)gasoline-directinjection(GDI)engine was studied by analyzing the mixture formation and combustion.Swirl was broken and dissipated gradually and the turbulence kinetic energy(TKE)was small in the compression process;however,tumble was strengthened and the TKE was strong in the compression process.For swirl around X axis(the axis of cylinder)and tumble around Y axis(the vertical direction of injector),droplets were attached to the cylinder liner by the centrifugal force and the mixture distribution was poor.For tumble around Zaxis(the direction of injector),the wall film in cylinder liner was thin and mixture distribution was homogeneous.Results showed that since the injector were installed on the wall of the cylinder liner in the OPTS-GDI engine,the spray angle was small and the mixture formation time was short.The 45° oblique axis tumble ratio of 1 was reasonable for the mixture formation and combustion for an OPTS-GDI engine.
基金supported by China First Auto Works Group Corporation R&D Center Program (Grant No. 56067028)
文摘In order to improve the fuel consumption and exhaust emission for gasoline engines,gasoline direct injection(GDI) system is spotlighted to solve these requirements.Thus,many researchers focus on the investigation of spray characteristics and the fuel formation of GDI injector.This paper presents a complete numerical and experimental characterization of transient gasoline spray from a high pressure injection system equipped with a modern single-hole electric controlled injector in a pressurized constant volume vessel.The numerical analysis is carried out in a one-dimensional model of fuel injection system which is developed in the AVL HYDSIM environment.The experimental analyses are implemented through a self-developed injection rate measurement device and spray evolution visualization system.The experimental results of injection rate and spray dynamics are taken to tune and validate the built model.The visualization system synchronize a high speed CMOS camera to obtain the spray structure,moreover,the captured images are taken to validate the injector needle lift process which is simulated in the model.The reliability of the built model is demonstrated by comparing the numerical results with the experimental data.The formed vortex structure at 0.8 ms is effectively disintegrated at 6.2 ms and the spray dynamics become rather chaotic.The fuel flow characteristics within injector nozzle extremely influence the subsequent spray evolution,and therefore this point should be reconsidered when building hybrid breakup GDI spray model.The spray tip speed reach the maximum at 1.18 ms regardless of the operation conditions and this is only determined by the injector itself.Furthermore,an empirical equation for the spray tip penetration is obtained and good agreement with the measured results is reached at a certain extent.This paper provides a methodology for the investigation of spray behavior and fuel distribution of GDI engine design.
文摘In order to investigate the effects of fuel injection distribution on the scrarnjet combustor performance, there are conducted three sets of test on a hydrocarbon fueled direct-connect scramjet test facility. The results of Test A, whose fuel injection is carried out with injectors located on the top-wall and the bottom-wall, show that the fuel injection with an appropriate close-front and centralized distribution would be of much help to optimize combustor performances. The results of Test B, whose fuel injection is performed at the optimal injection locations found in Test A, with a given equivalence ratio and different injection proportions for each injector, show that this injection mode is of little benefit to improve combustor performances. The results of Test C with a circumferential fuel injection distribution displaies the possibility of ameliorating combustor performance. By analyzing the effects of injection location parameters on combustor performances on the base of the data of Test C, it is clear that the injector location has strong coupled influences on combustor performances. In addition, an irmer-force synthesis specific impulse is used to reduce the errors caused by the disturbance of fuel supply and working state of air heater while assessing combustor performances.
基金supported by National Basic Research Program of China(973 Program)
文摘To achieve the electric field strength and the induced currents in equivalence in susceptibility tests with the high-level field radiation above 400 MHz,a double differential-mode(DM) current injection method based on directional couplers is proposed.Two cascaded symmetrical directional couplers compose a coupling device to inject the DM currents.When the coupling device is used,two devices are necessary to achieve the equivalence between radiation and injection,i.e.the equivalence between the injected voltages and the field strength,which is linear,regardless of the characteristics of the equipment under test(EUT).The results are verified by experiments using typical coaxial cables and nonlinear devices,where the equivalence between the nonlinear EUT responses induced by radiation and injection at both ends is achieved by using two coupling devices.At a frequency up to 1.75 GHz,the maximal experimental error is only 3.39%.The experimental results confirm the accuracy of the proposed method even both the EUTs work in the nonlinear region.The proposed method is applicable for radiated susceptibility(RS) testing of interconnected systems in the microwave frequency band.
基金supported by the Industrial Strategic Technology Development Program, 10042559‘Development of fuel injector for 200 bar gasoline direct injection system’ funded by the Ministry of Trade, Industry & Energy (MI, Korea)
文摘Concerns about environmental pollution and energy shortages have increased worldwide. One approach to reduce CO2 emissions from gasoline engines is to achieve stratified charge combustion with various injection ratios using port fuel injection (PFI) and direct injection. The combustion and emission characteristics of a 4-valve direct injection spark ignition (DISI) engine equipped with a dual injection system were investigated while the injection ratio was varied. When the direct injection ratio increased, the lean limit A/F was extended. This suggests that the dual injection gasoline engine with both PFI and direct injection can meet severe vehicle emission and fuel economy requirements. The dual injection system had higher combustion pressure than that of either a conventional or direct injection systems. Therefore, the engine power of a dual injection DISI engine would be higher than that of a single injection DISI engine. However, NOx emissions increased compared with the emission levels in both PFI and DISI systems.
文摘In order to study the hypotonic and rheological particularity of “three soft” coal seam in west Henan, China, this paper explored the stress and damage characteristics of crack in coal under condition of water injection fracturing based on ABAQUS platform;The cohesive element in T-P damage evolution criterion was used to describe the approximately linear relationship between crack width and extending distance in soft coal. The simulation results show that stress evolution and crack damage in soft coal is a gradually developing process under condition of water injection fracturing. When the static pressure is 4 - 10 MPa, and the injection time is about 1 - 2 hours, the damage range of crack in soft coal can basically reach an ideal data of 80 - 100 m, and then greatly improve the hypotonic performance of “three soft” coal seam.
基金The financial support by the National Key Research and Development Program of China(Grant No.2018YFC0809601)the National Natural Science Foundation of China(Grant No.51779252)+1 种基金the Major Technological Innovation Projects of Hubei,China(Grant No.2017AAA128)the Key Projects of the Yalong River Joint Fund of the National Natural Science Foundation of China(Grant No.U1865203)for this work are gratefully acknowledged。
文摘Natural fractures are generally well developed in most hydrocarbon and geothermal reservoirs,which can produce complex fracture networks due to the activation of fractures during hydraulic stimulation.The present paper is devoted to developing a method to investigate the activation characteristics of fracture under injection-shearing coupled condition at laboratory scale.The fluid is injected into the single-fractured granite until the fracture is activated based on the triaxial direct shear tests.The results show that injection process can significantly influence the shear stress distribution field,resulting in release of shear stress and relative slip between the opposite sides of the fractured surface.The injectioninduced activation of fracture is strongly dependent on the stress states.When the normal stress increases,the injection-induced activation pressure increases,and the comparatively high normal stress can restrain the fracture activation.The fracture deformation mechanisms during fluid injection are also discussed preliminarily with the experimental data.The sensitivity of shear stress to fluid injection increases with increase of shear stress level,while it decreases under high normal stress.The results can facilitate our understanding of the natural fracture activation behavior during fluid pressure stimulation.