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Beidou receiver based on anti-jamming antenna arrays with self-calibration for precise relative positioning
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作者 AN Yi KANG Ronglei +1 位作者 BAN Yalong YANG Shaoshuai 《Journal of Systems Engineering and Electronics》 SCIE CSCD 2024年第5期1132-1147,共16页
Unmanned aerial vehicles(UAVs)may be subjected to unintentional radio frequency interference(RFI)or hostile jamming attack which will lead to fail to track global navigation satellite system(GNSS)signals.Therefore,the... Unmanned aerial vehicles(UAVs)may be subjected to unintentional radio frequency interference(RFI)or hostile jamming attack which will lead to fail to track global navigation satellite system(GNSS)signals.Therefore,the simultaneous realization of anti-jamming and high-precision carrier phase difference positioning becomes a dilemmatic problem.In this paper,a distortionless phase digital beamforming(DBF)algorithm with self-calibration antenna arrays is proposed,which enables to obtain distortionless carrier phase while suppressing jamming.Additionally,architecture of high precision Beidou receiver based on anti-jamming antenna arrays is proposed.Finally,the performance of the algorithm is evaluated,including antenna calibration accuracy,carrier phase distortionless accuracy,and carrier phase measurement accuracy without jamming.Meanwhile,the maximal jamming to signal ratio(JSR)and real time kinematic(RTK)positioning accuracy under wideband jamming are also investigated.The experimental results based on the real-life Beidou signals show that the proposed method has an excellent performance for precise relative positioning under jamming when compared with other anti-jamming methods. 展开更多
关键词 Beidou receiver antenna array ANTI-JAMMING high precision distortionless carrier phase
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Wideband spectrum sensing using step-sampling based on the multipath nyquist folding receiver
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作者 Kai-lun Tian Kai-li Jiang +5 位作者 Sen Cao Jian Gao Ying Xiong Bin Tang Xu-ying Zhang Yan-fei Li 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第1期523-536,共14页
Wideband spectrum sensing with a high-speed analog-digital converter(ADC) presents a challenge for practical systems.The Nyquist folding receiver(NYFR) is a promising scheme for achieving cost-effective real-time spec... Wideband spectrum sensing with a high-speed analog-digital converter(ADC) presents a challenge for practical systems.The Nyquist folding receiver(NYFR) is a promising scheme for achieving cost-effective real-time spectrum sensing,which is subject to the complexity of processing the modulated outputs.In this case,a multipath NYFR architecture with a step-sampling rate for the different paths is proposed.The different numbers of digital channels for each path are designed based on the Chinese remainder theorem(CRT).Then,the detectable frequency range is divided into multiple frequency grids,and the Nyquist zone(NZ) of the input can be obtained by sensing these grids.Thus,high-precision parameter estimation is performed by utilizing the NYFR characteristics.Compared with the existing methods,the scheme proposed in this paper overcomes the challenge of NZ estimation,information damage,many computations,low accuracy,and high false alarm probability.Comparative simulation experiments verify the effectiveness of the proposed architecture in this paper. 展开更多
关键词 Wideband spectrum sensing Sub-Nyquist sampling Step-sampling Nyquist folding receiver(NYFR) Multisignal processing
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Crustal structure in the Anyuan Coal Mine and its adjacent areas of Jiangxi Province by P-wave receiver functions
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作者 Xingmian Zhang Meng Gong +5 位作者 Jian Lü Hongxing Li Jie Hu Junwen He Jianhua Peng Bingyue Liu 《Earthquake Research Advances》 CSCD 2024年第1期47-58,共12页
We collected high-quality teleseismic events recorded by 12 broadband seismographs deployed in the Anyuan Coal Mine and its adjacent areas in Pingxiang City,Jiangxi Province for nearly two years.The H-κ-c stacking me... We collected high-quality teleseismic events recorded by 12 broadband seismographs deployed in the Anyuan Coal Mine and its adjacent areas in Pingxiang City,Jiangxi Province for nearly two years.The H-κ-c stacking method was employed to obtain the crustal thickness and Poisson's ratio distribution,then the characteristics of crustal structure below the stations were obtained by using the time-domain linear inversion method.The crustal thickness in the Anyuan Coal Mine and its adjacent areas ranges from approximately 32~35 km,with an average thickness of 33 km,which is consistent with the crustal thickness results in South China from previous studies using the receiver function method.The average Poisson's ratio of the crustal bulk composition in the study area varies between 0.22 and 0.25,which is lower than the global value with a 0.27 average,indicating a predominantly intermediate-acidic or felsic crustal composition.There is a weak negative correlation between Poisson's ratio and crustal thickness estimates in the Anyuan Coal Mine and its adjacent areas,suggesting that the absence of mafic-ultramafic materials in the lower crust is associated with the process of crustal delamination.The velocity inversion results indicate that the crustal structure including three velocity discontinuity interfaces,with the first at a depth of approximately 1.5 km,the second at about 10~15 km,and the third being the Moho.The study also indicates that the results obtained by the H-κ-c stacking method are significantly better than those obtained by the H-κmethod,effectively reducing the standard deviation and dispersion of crustal thickness and vP/vSratio. 展开更多
关键词 Anyuan Coal Mine receiver function H-κ-c stacking Crustal thickness Poisson's ratio
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Crustal and uppermost mantle structure of the northeastern Qinghai-Xizang Plateau from joint inversion of surface wave dispersions and receiver functions with P velocity constraints
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作者 Pei Zhang Xiaodong Song +2 位作者 Jiangtao Li Xingchen Wang Xuezhen Zhang 《Earthquake Science》 2024年第2期93-106,共14页
Lithospheric structure beneath the northeastern Qinghai-Xizang Plateau is of vital significance for studying the geodynamic processes of crustal thickening and expansion of the Qinghai-Xizang Plateau. We conducted a j... Lithospheric structure beneath the northeastern Qinghai-Xizang Plateau is of vital significance for studying the geodynamic processes of crustal thickening and expansion of the Qinghai-Xizang Plateau. We conducted a joint inversion of receiver functions and surface wave dispersions with P-wave velocity constraints using data from the Chin Array Ⅱ temporary stations deployed across the Qinghai-Xizang Plateau. Prior to joint inversion, we applied the H-κ-c method(Li JT et al., 2019) to the receiver function data in order to correct for the back-azimuthal variations in the arrival times of Ps phases and crustal multiples caused by crustal anisotropy and dipping interfaces. High-resolution images of vS, crustal thickness, and vP/vSstructures in the Qinghai-Xizang Plateau were simultaneously derived from the joint inversion. The seismic images reveal that crustal thickness decreases outward from the Qinghai-Xizang Plateau. The stable interiors of the Ordos and Alxa blocks exhibited higher velocities and lower crustal vP/vSratios. While, lower velocities and higher vP/vSratios were observed beneath the Qilian Orogen and Songpan-Ganzi terrane(SPGZ), which are geologically active and mechanically weak, especially in the mid-lower crust.Delamination or thermal erosion of the lithosphere triggered by hot asthenospheric flow contributes to the observed uppermost mantle low-velocity zones(LVZs) in the SPGZ. The crustal thickness, vS, and vP/vSratios suggest that whole lithospheric shortening is a plausible mechanism for crustal thickening in the Qinghai-Xizang Plateau, supporting the idea of coupled lithospheric-scale deformation in this region. 展开更多
关键词 joint inversion receiver functions surface waves crustal thickness vP/vS ratio NE Qinghai-Xizang Plateau
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Crustal structure and shallow-focus seismic activities in the Sumatra subduction zone:Constrains from receiver function inversion
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作者 Xuelei Li Yuan Wang +3 位作者 Tianyao Hao Yuxin Yuan Zhuo Jia Jinpeng Luan 《Deep Resources Engineering》 2024年第3期1-11,共11页
The Sumatra subduction zone is located in the southwest of the Suna plate,between the Euro-Asia Plate and Indo-Austrilian Plates.With the obliquely subducting of the Indo-Austrilian Plate toward the the Euro-Asia Plat... The Sumatra subduction zone is located in the southwest of the Suna plate,between the Euro-Asia Plate and Indo-Austrilian Plates.With the obliquely subducting of the Indo-Austrilian Plate toward the the Euro-Asia Plate,complex tectonics,strong earthquakes and volcanoes have been observed in this area which has become a well experimental field used to study the subduction zone.In this work,we employed receiver function method to evaluate the S-wave velocity structure beneath 5 broadband seismic stations along the Sumatra subduction zone.We selected 332 receiver function waveforms with intelligent software and manual picking methods,including 130,34,42,29 and 97 receiver function waveforms corresponding to BKNI,GSI,LHMI,MNAI,and PMBI sta-tions,respectively.These stacked receiver function waveforms were applied to inversion to estimate Swave structure beneath each station based on a Neighborhood Algorithm(NA).Our results indicate that the sediment layers for GSI,LHMI and MNAI stations are more than 3 km thick,two stations of which are thicker than 6 km(e.g.GSI and LHMI).The difference of receiver function waveforms for NE,SW and W orientation at station GSI where is accompanied with strong thrust earthquakes suggests that there is a complicated structure beneath this station.Station BKNI and PMBI are located on the eastern side of the Sumatra fault and the thickness of their sediment layers is only~1 km.The crustal thickness for back-arc basin is within 30-36 km.However,the crustal thickness of forearc area varies from~26 km of the forearc ridge to 26-30 km of the forearc basin toward continent and its,which suggests that the down dip limit(slab-Moho intersection)of seismogenic zone is within 29-36 km in forearc and explains why the shallow-focus earthquakes play a dominant role in this area.The stable state for the inner wedge of forearc within a seismogenic circle provides a favorable environment for storing stress.Meanwhile,these faults caused by the subducting of Indo-Austrilian Plate constructed a condition(e.g.cracking of intact rocks and frictional sliding)in which it would trigger shallow-focus seismic activities(releasing stress). 展开更多
关键词 SUMATRA receiver function Subduction plate Seismic activities
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A seafloor electromagnetic receiver for marine magnetotellurics and marine controlled-source electromagnetic sounding 被引量:7
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作者 陈凯 魏文博 +2 位作者 邓明 伍忠良 余刚 《Applied Geophysics》 SCIE CSCD 2015年第3期317-326,466,共11页
In planning and executing marine controlled-source electromagnetic methods, seafloor electromagnetic receivers must overcome the problems of noise, clock drift, and power consumption. To design a receiver that perform... In planning and executing marine controlled-source electromagnetic methods, seafloor electromagnetic receivers must overcome the problems of noise, clock drift, and power consumption. To design a receiver that performs well and overcomes the abovementioned problems, we performed forward modeling of the E-field abnormal response and established the receiver's characteristics. We describe the design optimization and the properties of each component, that is, low-noise induction coil sensor, low-noise Ag/AgCI electrode, low-noise chopper amplifier, digital temperature-compensated crystal oscillator module, acoustic telemetry modem, and burn wire system. Finally, we discuss the results of onshore and offshore field tests to show the effectiveness of the developed seafloor electromagnetic receiver and its performance: typical E-field noise of 0.12 nV/m/rt(Hz) at 0.5 Hz, dynamic range higher than 120 dB, clock drift lower than 1 ms/day, and continuous operation of at least 21 days. 展开更多
关键词 MCSEM seafloor EM receiver seafioor electric field sensor chopper amplifier acoustic telemetry modem
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Concept and Design of a Novel High-Bandwidth,High-Sensitivity Differential Receiver for Optical Interconnections 被引量:1
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作者 余长亮 毛陆虹 +1 位作者 宋瑞良 肖新东 《Journal of Semiconductors》 EI CAS CSCD 北大核心 2008年第5期903-907,共5页
A novel high-bandwidth, high-sensitivity differential optical receiver without any additional cost compared to general optical receivers, is proposed for high-speed optical communications and interconnections. High ba... A novel high-bandwidth, high-sensitivity differential optical receiver without any additional cost compared to general optical receivers, is proposed for high-speed optical communications and interconnections. High bandwidth and high sensitivity are achieved through a fully differential transimpedance amplifier with balanced input loads and two photodetectors to convert the incident light into a pair of differential photogenerated currents,respectively. In addition,a corresponding 0.35μm standard CMOS optoelectronic integrated receiver with two 60μm × 30μm, 1. 483pF fingered p^+/n- well/p-substrate photodiodes is also presented. The simulation results demonstrate that it achieves a 1.37GHz bandwidth and a 81.9dBΩ transimpedance gain,supporting data rates up to at least 2Gbit/s. The device consumes a core area of 0. 198mm^2 and the optical sensitivity is at least - 13dBm for a 10^-12 bit error rate under a 2^15 - 1 PRBS input signal. 展开更多
关键词 high-bandwidth HIGH-SENSITIVITY CMOS optical receiver
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A High Speed,12-Channel Parallel,Monolithic Integrated CMOS OEIC Receiver
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作者 朱浩波 毛陆虹 +2 位作者 余长亮 陈弘达 唐君 《Journal of Semiconductors》 EI CAS CSCD 北大核心 2007年第9期1341-1345,共5页
The design and fabrication of a high speed, 12-channel monolithic integrated CMOS optoelectronic integrated circuit (OEIC) receiver are reported. Each channel of the receiver consists of a photodetector, a transimpe... The design and fabrication of a high speed, 12-channel monolithic integrated CMOS optoelectronic integrated circuit (OEIC) receiver are reported. Each channel of the receiver consists of a photodetector, a transimpedance amplifier,and a post-amplifier. The double photodiode structure speeds up the receiver but hinders responsivity. The adoption of active inductors in the TIA circuit extends the - 3dB bandwidth to a higher level. The receiver has been realized in a CSMC 0.6μm standard CMOS process. The measured results show that a single channel of the receiver is able to work at bit rates of 0.8- 1.4Gb/s. Altogether, the 12-channel OEIC receiver chip can be operated at 15Gb/s. 展开更多
关键词 CMOS OPTOELECTRONICS parallel receiver high speed
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A 12-Channel,30Gb/s,0.18μm CMOS Front-End Amplifier for Parallel Optic-Fiber Receivers
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作者 李智群 薛兆丰 +1 位作者 王志功 冯军 《Journal of Semiconductors》 EI CAS CSCD 北大核心 2006年第1期47-53,共7页
This paper presents a 12-channel,30Gb/s front-end amplifier realized in standard 0.18μm CMOS technology for parallel optlc-fiber receivers. In order to overcome the problem of inadequate bandwidth caused by the large... This paper presents a 12-channel,30Gb/s front-end amplifier realized in standard 0.18μm CMOS technology for parallel optlc-fiber receivers. In order to overcome the problem of inadequate bandwidth caused by the large parasitical capacitor of CMOS photo-detectors,a regulated-cascode structure and noise optimization are used in the design of the transimpedance amplifier. The experimental results indicate that, with a parasitical capacitance of 2pF,a single channel is able to work at bite rates of up to 2.5Gb/s,and a clear eye diagram is obtained with a 0. 8mVpp input. Furthermore, an isolation structure combined with a p^+ guard.ring (PGR), an n^+ guard-ring (NGR),and a deep-n-well (DNW) for parallel amplifier is also presented. Taking this combined structure, the crosstalk and the substrate noise coupling have been effectively reduced. Compared with the isolation of PGR or PGR + NGR,the measured results show that the isolation degree of this structure is improved by 29.2 and 8. ldB at 1GHz,and by 8. 1 and 2. 5dB at 2GHz,respectively. With a 1.8V supply,each channel of the front-end amplifier consumes a DC power of 85mW,and the total power consumption of 12 channels is about 1W. 展开更多
关键词 parallel optic-fiber receiver front-end amplifier regulated-cascode substrate noise coupling ISOLATION
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Iterative receivers for SFBC-OFDM systems with adaptive training scheme
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作者 井雅 徐晓东 +1 位作者 陈明 程时昕 《Journal of Southeast University(English Edition)》 EI CAS 2005年第2期127-131,共5页
This paper considers the design of iterative receivers for space-frequencyblock-coded orthogonal frequency division multiplexing (SFBC-OFDM) systems in unknown wirelessdispersive fading channels. An iterative joint ch... This paper considers the design of iterative receivers for space-frequencyblock-coded orthogonal frequency division multiplexing (SFBC-OFDM) systems in unknown wirelessdispersive fading channels. An iterative joint channel estimation and symbol detection algorithm isderived. In the algorithm, the channel estimator performs alternately in two modes. During thetraining mode, the channel state information (CSI) is obtained by a discrete-Fourier-transform-basedchannel estimator and the noise variance and covariance matrix of the channel response is estimatedby the proposed method. In the data transmission mode, the CSI and transmitted data is obtainediteratively. In order to suppress the error propagation caused by a random error in identifyingsymbols, a simple error propagation detection criterion is proposed and an adaptive training schemeis applied to suppress the error propagation. Both theoretical analysis and simulation results showthat this algorithm gives better bit-error-rate performance and saves the overhead of OFDM systems. 展开更多
关键词 space-frequency block-coded orthogonal frequency division multiplexing(SFBC-OFDM) iterative receiver channel estimation adaptive training scheme
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Constrained least squares algorithm for channel vector estimation in 2-D RAKE receiver
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作者 王建明 赵春明 《Journal of Southeast University(English Edition)》 EI CAS 2003年第1期1-4,共4页
Based on the fact that the variation of tile direction of arrival (DOA) isslower than that of the channel fading, the steering vector of the desired signal is estimatedfirstly using a subspace decomposition method and... Based on the fact that the variation of tile direction of arrival (DOA) isslower than that of the channel fading, the steering vector of the desired signal is estimatedfirstly using a subspace decomposition method and then a constrained condition is configured.Traffic signals are further employed to estimate the channel vector based on the constrained leastsquares criterion. We use the iterative least squares with projection (ILSP) algorithm initializedby the pilot to get the estimation. The accuracy of channel estimation and symbol detection can beprogressively increased through the iteration procedure of the ILSP algorithm. Simulation resultsdemonstrate that the proposed algorithm improves the system performance effectively compared withthe conventional 2-D RAKE receiver. 展开更多
关键词 2-D RAKE receiver channel estimation subspace decomposition constrained least squares
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An Implementation of a CMOS Down-Conversion Mixer for GSM1900 Receivers 被引量:2
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作者 褚方青 李巍 +1 位作者 苏彦锋 任俊彦 《Journal of Semiconductors》 EI CAS CSCD 北大核心 2006年第3期467-472,共6页
A 1.9GHz down-conversion CMOS mixer with a novel folded Gilbert cell,intended for use in GSM1900 (PCS1900) low-IF receivers,is fabricated in a RF 0.18μm CMOS process. The prototype demonstrates good performance at ... A 1.9GHz down-conversion CMOS mixer with a novel folded Gilbert cell,intended for use in GSM1900 (PCS1900) low-IF receivers,is fabricated in a RF 0.18μm CMOS process. The prototype demonstrates good performance at an intermediate frequency of 100kHz. It achieves a conversion gain of 6dB, SSB noise figure of 18. 5dB (1MHz IF) ,and IIP3 11.5dBm while consuming a 7mA current from a 3.3V power supply. 展开更多
关键词 GSM receiver LOW-IF MIXER CMOS RF integrated circuits
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A Low-Voltage,Low-Power CMOS High Dynamic Range dB-Linear VGA for Super Heterodyne Receivers 被引量:3
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作者 董桥 耿莉 邵志标 《Journal of Semiconductors》 EI CAS CSCD 北大核心 2007年第11期1690-1695,共6页
This paper presents a low-voltage low-power variable gain amplifier,which is applied in the automatic gain control loop of a super heterodyne receiver. Six stages are cascaded to provide an 81dB digitally controlled g... This paper presents a low-voltage low-power variable gain amplifier,which is applied in the automatic gain control loop of a super heterodyne receiver. Six stages are cascaded to provide an 81dB digitally controlled gain range in a 3dB step. The gain step error is less than 0.5dB. It operates at an intermediate frequency of 300kHz, and the power consumption is 1.35mW from a 1.8V supply. The prototype chip is implemented in a TSMC's 0.18μm 1P6M CMOS process and occupies approximately 0.24mm^2 . It is very suitable for portable wire- less communication systems. The measurement results agree well with the system requirements. 展开更多
关键词 variable gain amplifier low voltage low power super heterodyne receiver CMOS RF integratedcircuits
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Using receiver operating characteristic curves to evaluate the diagnostic value of the combination of multislice spiral CT and alpha-fetoprotein levels for small hepatocellular carcinoma in cirrhotic patients 被引量:30
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作者 Guang-Sheng Jia Guang-Long Feng +5 位作者 Jin-Ping Li Hai-Long Xu Hui Wang Yi-Peng Cheng Lin-Lin Yan Hui-Jie Jiang 《Hepatobiliary & Pancreatic Diseases International》 SCIE CAS CSCD 2017年第3期303-309,共7页
BACKGROUND: The various combination of multiphase enhancement multislice spiral CT (MSCT) makes the diagno- sis of a small hepatocellular carcinoma (sHCC) on the back- ground of liver cirrhosis possible. This stu... BACKGROUND: The various combination of multiphase enhancement multislice spiral CT (MSCT) makes the diagno- sis of a small hepatocellular carcinoma (sHCC) on the back- ground of liver cirrhosis possible. This study was to explore whether the combination of MSCT enhancement scan and alpha-fetoprotein (AFP) level ficiency for sHCC. could increase the diagnostic ef- METHODS: This study included 35 sHCC patients and 52 cir- rhotic patients without image evidence of HCC as a control group. The diagnoses were made by three radiologists em- ploying a 5-point rating scale, with postoperative pathologic results as the gold standard. Receiver operating characteristic (ROC) curve analysis was performed to evaluate the diag- nostic value of the three MSCT combination modes (arterial phase+portal-venous phase, arterial phase+delayed phase, arterial phase+portal-venous phase+delayed phase) and AFP levels for sHCC on the background of liver cirrhosis. RESULTS: The area under ROC curve (AUC), sensitivity, and specificity of the combination of arterial phase+portal- venous phase+delayed phase were 0.93, 93%, and 82%, respectively. The average AUC of the arterial phase+portal- venous phase+delayed phase combination was significantly greater than that of the arterial phase+portal-venous phase (AUC=0.84, P=0.01) and arterial phase+delayed phase (AUC=0.85, P=0.03). Arterial phase+portal-venous phase had a smaller AUC (0.84) than arterial phase+delayed phase (0.85), but the difference was insignificant (P=0.15). After combining MSCT enhancement scan with AFP, the AUC, sensitivity, and specificity were 0.95, 94%, and 83%, respectively, indicating a greatly increased diagnostic efficiency for sHCC. CONCLUSIONS: The combination of AFP and 3 phases MSCT enhancement scan could increase the diagnostic efficiency for sHCC on the background of liver cirrhosis. The application of ROC curve analysis has provided a new method and reference in HCC diagnosis. 展开更多
关键词 hepatocellular carcinoma receiver operating characteristic multi-slice spiral CT ALPHA-FETOPROTEIN delayed phase imaging
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法舒地尔缓解β-淀粉样蛋白1-42诱导的SH-SY5Y细胞凋亡
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作者 郭敏芳 张慧宇 +3 位作者 章培军 苏琴 贾思玮 尉杰忠 《中国组织工程研究》 CAS 北大核心 2025年第23期4939-4946,共8页
背景:法舒地尔对阿尔茨海默病小鼠脑内的线粒体动力学有调节作用,并且可以抑制神经炎症,但能否调节线粒体自噬和NLRP3炎症小体进而减轻β-淀粉样蛋白毒性尚不清楚。目的:探究法舒地尔对β-淀粉样蛋白1-42诱导的人源神经母细胞瘤细胞株SH... 背景:法舒地尔对阿尔茨海默病小鼠脑内的线粒体动力学有调节作用,并且可以抑制神经炎症,但能否调节线粒体自噬和NLRP3炎症小体进而减轻β-淀粉样蛋白毒性尚不清楚。目的:探究法舒地尔对β-淀粉样蛋白1-42诱导的人源神经母细胞瘤细胞株SH-SY5Y凋亡和线粒体自噬以及NLRP3炎症小体的调节作用。方法:将SH-SY5Y细胞接种于孔板内,细胞贴壁后分3组干预:对照组不加入任何药物,模型组加入20μmol/L β-淀粉样蛋白1-42,法舒地尔组同时加入20μmol/L β-淀粉样蛋白1-42与15 mg/L法舒地尔,干预24 h后,采用MTT法检测细胞活性,TUNEL染色检测细胞凋亡,qRT-PCR和Western blot检测凋亡相关蛋白表达,免疫荧光染色和Western blot检测线粒体自噬相关蛋白表达,免疫荧光染色和Western blot检测NLRP3炎症小体相关蛋白表达。结果与结论:(1)与对照组比较,模型组细胞活性降低、凋亡率升高(P<0.05);与模型组比较,法舒地尔组细胞活性升高、凋亡率降低(P<0.05);(2)qRT-PCR和Western blot检测结果显示,与对照组比较,模型组细胞Bax mRNA与蛋白表达升高(P<0.05),Bcl-2 mRNA与蛋白表达降低(P<0.05);与模型组比较,法舒地尔组细胞Bax mRNA与蛋白表达降低(P<0.05),Bcl-2 mRNA与蛋白表达升高(P<0.05);(3)免疫荧光染色和Western blot检测结果显示,与对照组相比,模型组细胞PINK1、帕金森病蛋白和LC3蛋白表达降低(P<0.05),p62蛋白表达升高(P<0.05);与模型组相比,法舒地尔组细胞PINK1、帕金森病蛋白和LC3蛋白表达升高(P<0.05),p62蛋白表达降低(P<0.05);(4)免疫荧光染色和Western blot检测结果显示,与对照组相比,模型组细胞NLRP3、ASC、Caspase-1和白细胞介素1β蛋白表达升高(P<0.05);与模型组相比,法舒地尔组细胞NLRP3、ASC、Caspase-1和白细胞介素1β蛋白表达降低(P<0.05);(5)结果表明,法舒地尔可以减轻β-淀粉样蛋白1-42诱导的SH-SY5Y细胞凋亡,其机制可能与激活线粒体自噬且抑制NLRP3炎症小体激活有关。 展开更多
关键词 法舒地尔 Β-淀粉样蛋白 神经细胞 细胞凋亡 线粒体自噬 炎症小体
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Prediction of Abdominal Visceral Obesity From Body Mass Index,Waist Circumference and Waist-hip Ratio in Chinese Adults:Receiver Operating Characteristic Curves Analysis 被引量:55
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作者 WEI-PINGJIA JUN-XILU +3 位作者 KUN-SANXIANG Yu-QIANBAO HUI-JUANLU ANDLEICHEN 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2003年第3期206-211,共6页
Objective To evaluate the sensitivity and specificity of body mass index (BMI), waist circumference (WC) and waist-to-hip ratio (WHR) measurements in diagnosing abdominal visceral obesity. Methods BMI, WC, and WHR wer... Objective To evaluate the sensitivity and specificity of body mass index (BMI), waist circumference (WC) and waist-to-hip ratio (WHR) measurements in diagnosing abdominal visceral obesity. Methods BMI, WC, and WHR were assessed in 690 Chinese adults (305 men and 385 women) and compared with magnetic resonance imaging (MRI) measurements of abdominal visceral adipose tissue (VA). Receiver operating characteristic (ROC) curves were generated and used to determine the threshold point for each anthropometric parameter. Results 1) MRI showed that 61.7% of overweight/obese individuals (BMI≥25 kg/m2) and 14.2% of normal weight (BMI<25 kg/m2) individuals had abdominal visceral obesity (VA≥100 cm2). 2) VA was positively correlated with each anthropometric variable, of which WC showed the highest correlation (r=0.73-0.77, P<0.001). 3) The best cut-off points for assessing abdominal visceral obesity were as followed: BMI of 26 kg/m2, WC of 90 cm, and WHR of 0.93, with WC being the most sensitive and specific factor. 4) Among subjects with BMI≥28 kg/m2 or WC≥95 cm, 95% of men and 90% of women appeared to have abdominal visceral obesity. Conclusion Measurements of BMI, WC, and WHR can be used in the prediction of abdominal visceral obesity, of which WC was the one with better accuracy. 展开更多
关键词 Body mass index (BMI) Abdominal visceral fat Anthropometric parameters receiver operating characteristic (ROC) curves
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S-wave velocity structure beneath Changbaishan volcano inferred from receiver function 被引量:6
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作者 Jianping Wu Yuehong Ming Lihua Fang Weilai Wang 《Earthquake Science》 CSCD 2009年第4期409-416,共8页
The S wave velocity structure in Changbaishan volcanic region was obtained from teleseismic receiver function modeling. The results show that there exist distinct low velocity layers in crust in volcano area. Beneath ... The S wave velocity structure in Changbaishan volcanic region was obtained from teleseismic receiver function modeling. The results show that there exist distinct low velocity layers in crust in volcano area. Beneath WQD station near to the Tianchi caldera the low velocity layer at 8 km depth is 20 km thick with the lowest S-wave velocity about 2.2 km/s At EDO station located 50 km north of Tianchi caldera, no obvious crustal low velocity layer is detected. In the volcanic region, the thickness of crustal low velocity layer is greater and the lowest velocity is more obvious with the distance shorter to the caldera. It indicates the existence of the high temperature material or magma reservoir in crust near the Tianchi caldera. The receiver functions and inversion result from different back azimuths at CBS permanent seismic station show that the thickness of near surface low velocity layer and Moho depth change with directions. The near surface low velocity layer is obviously thicker in south direction. The Moho depth shows slight uplifting in the direction of the caldera located. We con- sider that the special near surface velocity structure is the main cause of relatively lower prominent frequency of volcanic earthquake waveforms recorded by CBS station. The slight uplifting of Moho beneath Tianchi caldera indicates there is a material exchanging channel between upper mantle and magma reservoir in crust. 展开更多
关键词 CHANGBAISHAN VOLCANO seismic velocity structure receiver function
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ANGPTL4 TSP-1及CyPA与脑卒中后癫痫患者认知功能的关系
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作者 高灵利 方建 +2 位作者 李晓晖 李延红 耿智凡 《中国实用神经疾病杂志》 2025年第1期63-67,共5页
目的探讨血管生成素样蛋白4(ANGPTL4)、凝血酶敏感蛋白-1(TSP-1)、亲环素A(CyPA与脑卒中后癫痫患者认知功能的关系。方法选取2021-01—2022-12河南大学第一附属医院神经内科收治的100例脑卒中后癫痫病例进行观察,按简易精神状态量表(MM... 目的探讨血管生成素样蛋白4(ANGPTL4)、凝血酶敏感蛋白-1(TSP-1)、亲环素A(CyPA与脑卒中后癫痫患者认知功能的关系。方法选取2021-01—2022-12河南大学第一附属医院神经内科收治的100例脑卒中后癫痫病例进行观察,按简易精神状态量表(MMSE)划分认知障碍标准将患者分为认知障碍组(50例)和认知正常组(50例),应用酶联免疫吸附试验(ELISA)检测2组患者的血清ANGPTL4、TSP-1、CyPA水平,MMSE量表测评2组患者的认知功能。结果与认知正常组比较,认知障碍组患者MMSE评分降低,ANGPTL4、TSP-1、CyPA水平升高(P<0.05);与轻度认知障碍患者比较,中度认知障碍患者血清ANGPTL4、TSP-1、CyPA水平升高(P<0.05);与中度认知障碍患者比较,重度认知障碍患者血清ANGPTL4、TSP-1、CyPA水平升高(P<0.05)。在脑卒中后癫痫患者中,血清ANGPTL4、TSP-1、Cy PA与MMSE评分各维度均呈负相关(P<0.05)。结论脑卒中后癫痫会降低MMSE评分,提高患者血清ANGPTL4、TSP-1、CyPA水平。ANGPTL4、TSP-1、CyPA水平越高,患者认知功能障碍越严重。 展开更多
关键词 脑卒中后癫痫 血管生成素样蛋白4 凝血酶敏感蛋白-1 亲环素A 认知功能
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The usability of GNSS mass-market receivers for cadastral surveys considering RTK and NRTK techniques 被引量:2
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作者 Paolo Dabove 《Geodesy and Geodynamics》 2019年第4期282-289,共8页
Nowadays many positioning techniques and methods are applied to the cadastral surveys. Starting from last decade, GPS/GNSS positioning had become one of the most used methodology thanks to the rapid development of sat... Nowadays many positioning techniques and methods are applied to the cadastral surveys. Starting from last decade, GPS/GNSS positioning had become one of the most used methodology thanks to the rapid development of satellite-based positioning and to the appearance of GNSS mass-market receivers and antennas. Methods based on these instruments are more affordable than the conventional ones even if their use for precise positioning is not so intuitive. This study is aimed to evaluate the use of singlefrequency GPS/GNSS mass-market receivers for cadastral surveys, considering both single-base RealTime Kinematic(RTK) and Network Real-Time Kinematic(NRTK) methodologies. Furthermore, a particular tool for predicting and estimating the occurrence of false fix of the phase ambiguities has been considered, in order to improve the accuracy and precision of the solutions. Considering the single-base positioning, the research results showed the difference of a few centimetres between the reference coordinates and the estimated ones if the distance between master and rover is less than 3 km, while considering the network positioning and the Virtual Reference Station correction, the difference are about a couple of centimetres for East and North component, and about 5 cm for the Up. 展开更多
关键词 GNSS CADASTRAL surveying RTK NRTK positioning Mass-market receiveRS
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自旋-轨道耦合作用下极化激元凝聚中的调制不稳定性
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作者 陈海军 《原子与分子物理学报》 CAS 北大核心 2025年第6期136-143,共8页
利用线性稳定性分析方法,对存在自旋-轨道耦合(SOS)作用的二维极化激元玻色-爱因斯坦凝聚(BEC)系统中的调制不稳定性(MI)进行了研究.分析了组分内部,组分之间以及SOC相互作用对系统调制不稳定性的影响.结果显示,当系统内部不存在SOC作用... 利用线性稳定性分析方法,对存在自旋-轨道耦合(SOS)作用的二维极化激元玻色-爱因斯坦凝聚(BEC)系统中的调制不稳定性(MI)进行了研究.分析了组分内部,组分之间以及SOC相互作用对系统调制不稳定性的影响.结果显示,当系统内部不存在SOC作用,组分之间的相互作用为0,组分内部存在排斥作用时,不会出现调制不稳定性,组分内部存在吸引作用时,会出现调制不稳定性,并且调制不稳定性区间长度随吸引作用的增强而增加;组分之间相互作用不为0时,组分之间的相互作用以平方形式出现,其正负不会对调制不稳定性产生实质性影响.存在SOC相互作用时,SOC相互作用会引起增益谱曲线的不规则振荡,破坏原来的调制不稳定性区间. 展开更多
关键词 极化激元凝聚 调制不稳定性 自旋-轨道耦合 双分量
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