Epidemiological Study of Ametropia at the CHU-BSS of Kati

Introduction: Ametropias or refractive errors are pathologies commonly encountered in ophthalmology characterized by the projection on the retina of a blurry image. There are several types of ametropia and each of them has a specific means of correction. In the literature, numerous data have been reported on the issue through studies that were mostly carried out on infant populations. To better treat ametropia in a more formal way, it is important to know their general characteristics within a larger population, hence the present investigation, the aim of which is to carry out an epidemiological study of ametropia at the Kati University Hospital-BSS. Materials and Methods: The study was carried out at Kati University Hospital-BSS between January 1 and December 31, 2022 and included 663 ametropic patients of all ages. Results: During the study period, 663 cases of ametropia were diagnosed out of 1678 new consultations, representing an incidence of 39.51%. Patients aged between 21 and 40 years were more affected. Depending on the type, these ametropias were dominated by compound astigmatism with 68.75% followed by isolated hyperopia and isolated astigmatism. Visual fatigue was the most mentioned reason for consultation. The female gender was in the majority with 70.9%. Low ametropia (Discussion: The growing visual needs of young people, especially with new information and communication technologies, would push them to consult the ophthalmologist more, and therefore to want optical correction in the event of a refractive anomaly, which would partly explain their high frequency in this age group. Conclusion: It is important to know the general characteristics of ametropia in the general population in order to improve the quality of life of patients affected by it through efficient therapeutic solutions.

Quantitative analysis of optic disc changes in school-age children with ametropia based on artificial intelligence

AIM:To explore changes in the optic disc and peripapillary atrophy(PPA)in school-age children with ametropia using color fundus photography combined with artificial intelligence(AI)technology.METHODS:Based on the retrospective case-controlled study,226 eyes of 113 children aged aged 6–12y were enrolled from October 2021 to May 2022.According to the results of spherical equivalent(SE),the children were divided into four groups:low myopia group(66 eyes),moderate myopia group(60 eyes),high myopia group(50 eyes)and emmetropia control group(50 eyes).All subjects underwent un-aided visual acuity,dilated pupil optometry,best-corrected visual acuity(BCVA),intraocular pressure,ocular axis measurement and color fundus photography.RESULTS:The width of PPA,horizontal diameter ratio of PPA to the optic disc and area ratio of PPA to the optic disc were significantly different among the four groups(P<0.05).The width of the nasal and temporal neuroretinal rim,the roundness of the optic disc,the height of PPA,the vertical diameter ratio of PPA to the optic disc,and the average density of PPA in the high myopia group were significantly different compared with the other three groups(P<0.05).There were strong negative correlations between SE and area ratio of PPA to the optic disc(r=-0.812,P<0.001)and strong positive correlation between axial length(AL)and area ratio of PPA to the optic disc(r=0.736,P<0.001).CONCLUSION:In school-age children with high myopia,the nasal and temporal neuroretinal rims are narrowed and even lost,which have high sensitivity.The area ratio of the PPA to the optic disc could be used as an early predictor of myopia progression,which is of great significance for the development prevention and management of myopia.

早产儿学龄前屈光不正的影响因素

目的:分析早产儿学龄前屈光不正的影响因素。方法:选取2023年1—6月于中山市人民医院进行眼科检查的学龄前早产儿250例作为研究对象,通过调查问卷形式统计其临床资料。统计儿童的屈光正常、屈光不正发生情况,比较屈光正常组、屈光不正组屈光状态情况,分析早产儿学龄前屈光不正的影响因素。结果:屈光正常组角膜屈光力、眼轴长度、前房深度高于屈光不正组,晶状体厚度低于屈光不正组,差异有统计学意义(P<0.001)。屈光正常组胎龄、出生体质量高于屈光不正组,每天近距离学习时间短于屈光不正组,每天户外活动时间长于屈光不正组,差异有统计学意义(P<0.05);两组性别、年龄、娩出方式、体质量、胎龄、父母屈光状态情况比较,差异无统计学意义(P>0.05)。胎龄小、出生体质量低、每天近距离学习时间长、每天户外活动时间短是早产儿学龄前屈光不正的危险因素(P<0.05)。结论:中山地区早产儿学龄前屈光不正表现为角膜屈光力弱、前房浅、晶状体厚、眼轴长度短。胎龄小、出生体质量低、每天近距离学习时间长、每天户外活动时间短是早产儿学龄前屈光不正的危险因素,应重视相关情况,早期治疗早产儿屈光状态发育相关眼病。

巩膜镜矫正屈光不正的安全性

目的 探讨硬性巩膜接触镜在矫正屈光不正方面的安全性。方法 前瞻性研究,选取96例(192眼)近视患者(度数-20.00~0 D,散光度数0~3.50 D)为研究对象,分为试验组(配戴硬性巩膜接触镜)和对照组[配戴硬性角膜接触镜(RGP)],每组48例,分别于戴镜前、戴镜当天、戴镜后1周、戴镜后1个月及戴镜后3个月时检测并比较两组患者眼部相关参数指标[最佳矫正视力、角膜内皮细胞密度、六角形细胞比率、泪膜破裂时间(BUT)、眼压、角膜荧光素染色评分、结膜充血及睫状充血评分],观察是否出现眼部异常改变。结果 戴镜前至戴镜3个月期间,两组患者最佳矫正视力均≥1.00;戴镜后3个月时,与戴镜前比较,试验组患者角膜内皮细胞密度轻微下降,六角形细胞比率轻微上升,但差异均无统计学意义(均为P>0.05);戴镜前及戴镜后3个月时,试验组角膜内皮细胞密度及六角形比率均较对照组稍高,但差异均无统计学意义(均为P>0.05)。戴镜前、戴镜当天、戴镜后1周、戴镜后1个月及戴镜后3个月时,试验组与对照组患者BUT比较,差异均无统计学意义(均为P>0.05)。戴镜前、戴镜当天、戴镜后1周、戴镜后1个月及戴镜后3个月试验组与对照组患者眼压比较,差异均无统计学意义(均为P>0.05)。戴镜前及戴镜后3个月时,两组患者角膜荧光染色评级、结膜充血及睫状充血评级比较,差异均无统计学意义(均为P>0.05)。戴镜后3个月时,试验组患者均未出现结膜及角膜水肿等异常改变。结论 硬性巩膜接触镜与RGP具有一致的安全性与矫正屈光不正的有效性,值得推广及应用。

不同阿托品浓度治疗近视性屈光不正儿童近视的对比研究

目的研究不同阿托品浓度对近视性屈光不正儿童近视进展的影响。方法选取2021年1月至2022年12月间我院收治的80例近视性屈光不正儿童作为研究对象。随机将患者分为低浓度组(n=40,给予0.01%阿托品滴眼液)和高浓度组(n=40,给予1.0%阿托品滴眼液)。分析比较两组治疗前后屈光度、眼轴、眼压以及不良反应发生率。结果治疗后与治疗前相比,两组的屈光度、眼轴、眼压均有显著改善(P<0.05);但组间的屈光度、眼轴、眼压对比均无显著差异(P>0.05)。低浓度组的口干、视物模糊、皮肤干燥和畏光不良反应发生率(5.00%)明显低于高浓度组(20.00%)(P<0.05)。结论0.01%与1.0%的阿托品滴眼液均有助于改善儿童的屈光度、眼轴、眼压,但低浓度阿托品滴眼液治疗的不良反应发生率更低。

江阴市学龄前儿童屈光状态调查

目的:了解江阴市学龄前儿童屈光不正现状,为学龄前儿童视力健康防护工作提供指导。方法:选取2023年9—12月江阴全市范围幼儿园内41511名学龄前(3~6岁)儿童作为研究对象,均进行屈光筛查,统计学龄前儿童屈光状态。结果:41511名学龄前儿童中,近视、远视、散光、屈光参差分别检出663人、2023人、10984人、900人,检出率分别为1.60%、4.87%、26.46%、2.17%。不同性别学龄前儿童近视、散光以及屈光参差检出率比较,差异无统计学意义(P>0.05);女童远视检出率高于男童(P<0.05)。不同年龄学龄前儿童近视、散光以及屈光参差检出率比较,总体有统计学差异(P<0.05);不同年龄学龄前儿童远视检出率比较,差异无统计学意义(P>0.05);其中,5岁儿童各类型屈光不正检出率最高。结论:江阴市学龄前儿童散光检出率最高,其次分别为远视、屈光参差、近视,女童远视检出率高于男童,5岁儿童各类型屈光不正检出率最高。卫生部门应加强江阴市学龄前儿童屈光状态筛查工作,及时发现学龄前儿童视力变化及屈光不正状态,加强眼保健的宣教,尽早进行干预,提高学龄前儿童的视力健康水平。

上海市长宁区3岁~6岁儿童视力与屈光状态调查

目的:调查上海市长宁区3岁~6岁儿童的视力与屈光状态。方法:选取上海市长宁区2021年4—6月9家幼儿园入园幼儿1 590人作为研究对象,对所有儿童行视力及屈光度检测。分析当地儿童视力及屈光情况,探讨各指标的相关性。结果:长宁区3岁~6岁儿童1 590人中视力低常202人,视力低常率12.70%,单眼视力低常12人(5.94%),左眼5人(2.48%),右眼7人(3.47%);双眼视力低常190人(94.06%)。6岁儿童低常率高于3岁~5岁儿童,5岁儿童低常率高于3岁~4岁儿童,差异有统计学意义(P<0.05)。高度近视组等效球镜度(SE)小于低度近视组与中度近视组,前房深度(AD)小于低度近视组,眼轴长度(AL)大于低度近视组、中度近视组,差异有统计学意义(P<0.05)。Pearson相关性分析显示,视力异常儿童SE与AD、AL呈正相关,AD与AL呈正相关(P<0.05)。结论:3岁~6岁学龄前儿童年龄大者视力低常风险高,不同近视程度的患儿眼功能及屈光状态存在差异,SE与AD、AL间相互呈正相关。

Artificial intelligence in the anterior segment of eye diseases

Ophthalmology is a subject that highly depends on imaging examination.Artificial intelligence(AI)technology has great potential in medical imaging analysis,including image diagnosis,classification,grading,guiding treatment and evaluating prognosis.The combination of the two can realize mass screening of grass-roots eye health,making it possible to seek medical treatment in the mode of“first treatment at the grass-roots level,two-way referral,emergency and slow treatment,and linkage between the upper and lower levels”.On the basis of summarizing the AI technology carried out by scholars and their teams all over the world in the field of ophthalmology,quite a lot of studies have confirmed that machine learning can assist in diagnosis,grading,providing optimal treatment plans and evaluating prognosis in corneal and conjunctival diseases,ametropia,lens diseases,glaucoma,iris diseases,etc.This paper systematically shows the application and progress of AI technology in common anterior segment ocular diseases,the current limitations,and prospects for the future.

TICL V4c植入术后拱高对散光轴旋转角度的影响

目的 分析有晶体眼散光型人工晶体(TICl V4c)植入术后拱高对人工晶体散光轴旋转角度的影响。方法 选取眼科接受TCIL V4c植入术的近视患者89例(174眼),按照术后1周拱高的大小分为低拱高组、中拱高组以及高拱高组,术前检测患者裸眼视力(UCVA)、最佳矫正视力(BCVA)、屈光情况(球镜度数及柱镜度数)、非接触式眼压(IOP)、前房深度(ACD)以及内皮细胞计数(ECD);术后随访2年,记录患者的拱高变化情况及散光轴旋转角度情况,分析拱高与散光轴旋转角度的关系。结果 TICl V4c植入术后2年,低、中、高拱高组3组患者术后平均UCVA均高于术前(P<0.01);术后2年,3组患者的UCVA(0.97±0.24)好于术前BCVA(t=-8.78,P<0.01);3组近视患者术前的平均球镜度(-10.10±3.76)D提升至术后的(-0.39±0.81)D,术前的平均柱镜度(-2.36±1.03)D提升至术后的(-0.44±1.53)D(P<0.01);术后随访3组患者IOP、ECD均保持在正常范围内,且与术前比较,差异无统计学意义(P>0.05);所有患者术后均未发生青光眼、视网膜脱离以及葡萄膜炎等严重并发症;随访2年中3组患者的拱高变化不明显(P>0.05);患者晶体散光轴均发生不同程度的旋转,相关性分析表明,拱高与散光轴旋转角度不存在相关性(r=-0.117,P>0.05)。结论 TICL V4c植入术具有良好的有效性和安全性,术后产生的拱高对散光轴旋转角度并无明显影响。

Development of biomedical publications on ametropia research in PubMed from 1845 to 2010:a bibliometric analysis

We have carried out a bibliometric analysis on the development of ametropia literature to determine its growth rule and tendency, and to provide the basis for the problems related to ametropia research. Literatures that contained the descriptors of ametropia in title or paper published before Nov. 10, 2010 in PubMed databases (www.ncbi.nlm.nih.gov/Pubmed) were selected. As bibliometric indicators of ametropia, biomedical journals referring to ophthalmology by ISSN were calculated. The principal bibliometric indicators: Price's and Bradford's laws were applied on the increase or dispersion of scientific literature, the participation index of languages and the journals. By means of manual coding, literatures were classified according to documents study and statistical analysis. The literatures cited in ametropia, astigmatism, myopia and hypermetropia had accumulated to 26475, which consists of Review (n =1560), Randomized Controlled Trial (n =776), Practice Guideline (n =10), Meta-Analysis (n=23), Letter (n=1222), Editorial (n =328), Clinical Trial ( n =1726) and Others (n=20830); and Humans (n=23073), Animals (n=1434) and Others ( n=1968). 1136 literatures were included in PubMed Central, 22384 in MEDLINE and 2955 in others. The ametropia literatures rose every 5 years which of the ametropia-year cumulated amount of the literatures had three periods: before 1900, slowly increasing from 1901 to 1950, rapidly rising from 1951 to 2010 (increased approximate exponentiation exponent). Sixty kinds of languages were listed in PubMed databases, of which English was dominant for aborting to ametropia research documents before 2010 (77.32%, 20471/26475). The document language of top eight accounted for 95.58% (English, German, French, Japanese, Russian, Italian, Spanish, Chinese), and others for 4.42% (1171/26475). The SCI database includes 48 ophthalmologic journals and the impact factor of 39 journals is >= 1 on Thomson-Reuters in 2010. Of 48 ophthalmologic journals, there were 14785 documents (55.85%) of ametropia, astigmatism, myopia, and hypermetropia. Others were without exception. The bibliometric analysis results show that ametropia literature are increased progressively, approximate exponentiation Exponent during 1951-2010. In addition, ametropia research has become more popular since nearly half century.

Efficacy of Progressive Addition Lenses in the Treatment of Ametropia after the Single Eye's IOL Implantation

Purpose: To investigate the efficacy of progressive addition lenses on the treatment of ametropia and loss of accomodation after the single eye's IOL implantation. Methods:.Eighty four patients undergoing IOL implantation in single eyes were prescribed with progressive addition lenses for ametropia correction and regularly followed up to observe subsequent correction effect. Results:.Among these 84 patients,.72 could comfortably adapt to the use of progressive addition lenses to improve visual acuity and accomondation,while the remaining 12 patients failed to accomodate the usage of progressive addition lenses. Conclusion:.Wearing progressive addition lenses acts as a relatively feasible approach to improve visual acuity and alleviate disorders of accomodation for patients who underwent IOL implantation in single eyes..The patients should be prescribed with progressive lenses under professional instructions and guidance.

Ametropias in Kinkala: Epidemiological and Clinical Aspects

Ametropia is one of the leading causes of visual impairment. This study describes epidemiological and clinical aspects of ametropia as part of a free medical care program in Kinkala, Republic of Congo. Patients and Methods: We conducted a cross-sectional study from August 25th to September 24th, 2019;patients presenting complaints suggestive of ametropia were evaluated. The ametropia was determined by the objective method under cyclopentolate eye drops according to the following protocol: 3 applications of one drop every 5 minutes, followed by auto-refractometry at least 45 minutes after the first instillation. The auto-refractometer gave us the objective refraction. An anatomical examination was performed in order to eliminate any organic pathology. Results: Of the 2352 patients received, only 137 patients were included in our survey. Of the 137, 14 were emmetropic. Astigmatism was the most common ametropia. Its axis reversed with age, with more than 65% of direct astigmatism before age 40. There was nearly 65% of reversed astigmatism at 60 years and over. In spherical equivalents, hyperopia accounted for more than 80% of ametropia. Conclusion: Ametropia in Kinkala is dominated by astigmatism. Spherical equivalent, hyperopia represents more than 80% of refractive error.

Heredo-Familial Expression of Ametropia among Siblings of a Nigerian Family

A case series of 4 siblings who had auto-refraction and subjective refraction, refinement was with 0.25 Jackson Cross Cylinder. Presenting complaint was either blurring of distant vision or missing eye glasses. The eldest sibling started using eye glasses at 15 years of age while the other siblings commenced much earlier. Presenting visual acuities in 7 eyes ranged from 6/9 to 6/18, one eye of the eldest sibling had visual acuity of 6/36. Spherical errors had gender bias with the males more likely to be hypermetropic and the females more likely to be myopic. However, cylinder powers and axes were closely related in all siblings. It was concluded that heredo-familial traits could partly account for some of the striking similarities noted in the outcomes of refraction among the siblings.

新型硬性角膜接触镜润滑液安全性和有效性评价

目的评价一种国产新型硬性角膜接触镜润滑液的安全性和有效性。方法选择2020年11月至2021年6月在安徽医科大学第二附属医院眼科门诊接受硬性角膜接触镜验配的近视患者为研究对象,共82例164只眼,使用计算机程序法随机分为试验组和对照组,每组41例82眼,试验组使用新型硬性角膜接触镜润滑液,对照组使用博士伦硬性角膜接触镜润滑液。观察并记录患者戴镜前、戴镜1周、1个月、3个月的检查结果,包括矫正视力、主观症状、泪膜破裂时间(BUT)、角膜荧光素染色评分、结膜充血情况。结果两组患者矫正视力≥1.0的比例在戴镜1周、1个月、3个月差异均无统计学意义(P>0.05),主观症状评分的差异也无统计学意义(P>0.05),两组润滑液的有效性指标差异无统计学意义;两组患者在各时间点的BUT、角膜荧光素染色评分、结膜充血情况的差异均无统计学意义(P>0.05),两组润滑液的安全性指标差异无统计学意义。结论国产新型硬性角膜接触镜润滑液的临床应用安全有效。

兰州市中小学生屈光状态筛查

目的:对兰州市中小学生的屈光状态进行调查分析,了解兰州市中小学生筛查性屈光不正的流行病学特征。方法:采用横断面研究方法,用随机分层抽样法抽取2021年4至12月在甘肃省兰州市47所学校的中小学生作为调查对象。以学校为单位,采用国际标准视力表检查视力,采用非睫状肌麻痹的电脑自动验光仪进行屈光检查。裸眼视力<0.8为视力低下,具体分为:近视为等效球镜度≥-0.75DS;远视为等效球镜度≥+2.00 DS;散光为柱镜度≥1.00 DC;屈光参差为双眼屈光度数差值(等效球镜度)≥1.00 DS。比较不同年级不同屈光状态人数所占的百分比。结果:共纳入40302人,其中男21328人,女18974人;汉族37938人,少数民族2364人。小学、初中、高中各26122、9346和4834人。视力低下的总检出率为59.1%(23832/40302),小学、初中和高中年级视力低下的检出率分别为48.8%(12748/26122),76.9%(7189/9346)和87.9%(4250/4834)。近视的总检出率为63.3%(25521/40302),其中,小学、初中和高中筛查性近视的检出率分别为51.4%(13438/26122),84.4%(7888/9346)和86.8%(4195/4834)。筛查性视力低下、远视、近视、散光及屈光参差的检出率在低中高年级间比较差异均有统计学意义(均P<0.001)。结论:兰州市中小学生视力低下和近视人群的检出率高于国家平均水平,且随着年级的增加检出率逐渐升高。

虚拟现实-图像视觉诱发电位用于客观评定单眼屈光不正视觉损伤的价值

目的研究单眼不同程度视觉损伤情况下,双眼同时刺激与单眼刺激时虚拟现实-图像视觉诱发电位(virtual reality-pattern visual evoked potential,VR-PVEP)P100波形的特点。方法选取视力正常(采用小数记录法,远视力≥0.8且近视力≥0.5)的青年志愿者55名,使用插片法模拟单眼屈光不正视觉损伤,分别使单眼近视力与远视力之和≤0.2(A组,即重度视觉损伤)、0.2<近视力与远视力之和<0.8(B组,即中度视觉损伤)、近视力与远视力之和≥0.8(C组,即轻度视觉损伤)。同时,将双眼正常视力设为对照组。在16×16、24×24、32×32、64×644种空间频率下对单眼和双眼同时刺激所测得的VR-PVEPP100峰时进行比较。结果A组中视觉损伤眼与双眼同时视测得的P100峰时在24×24、32×32和64×64空间频率下的差异均有统计学意义(P<0.05),视觉损伤眼与健眼测得的P100峰时在64×64空间频率下的差异具有统计学意义(P<0.05)。B组中视觉损伤眼与双眼同时视测得的P100峰时在16×16、24×24和64×64空间频率下的差异均有统计学意义(P<0.05),视觉损伤眼与健眼测得的P100峰时在64×64空间频率下的差异具有统计学意义(P<0.05)。C组中视觉损伤眼与双眼同时视测得的P100峰时在全空间频率下的差异均无统计学意义(P>0.05)。对照组的单眼视与双眼同时视测得的P100峰时在全空间频率下的差异均无统计学意义(P>0.05)。结论VR-PVEP可用于对单眼中、重度视觉损伤者进行视力评估,能够反映屈光不正导致的视觉损伤眼的视力损伤程度,在视觉功能客观评定及法医临床鉴定中具有应用价值。

VTS4疗法联合传统综合疗法治疗屈光不正性弱视的效果

目的:探讨视觉训练系统4(VTS4)疗法联合传统综合疗法治疗屈光不正性弱视的效果。方法:以中国人民解放军联勤保障部队第九一〇医院眼科于2021年5月-2022年7月收治的173例屈光不正性弱视患儿为研究对象,按照随机数字表法分为观察组和对照组。对照组(n=86)给予传统综合疗法,观察组(n=87)在对照组的基础上给予VTS4疗法。观察两组视功能、眼调节功能、视力水平。结果:干预前两组立体视正常率、双眼融象正常率对比,差异均无统计学意义(P>0.05);干预后,两组立体视正常率、双眼融象正常率均升高,且观察组均高于对照组(P<0.05)。干预前两组调节幅度(AMP)、调节灵敏度(AF)及调节滞后量对比,差异均无统计学意义(P>0.05);干预后,两组AMP、AF均上升,且观察组均高于对照组,调节滞后量均降低,且观察组低于对照组(P<0.05)。干预前两组视力水平对比,差异无统计学意义(P>0.05);干预后两组视力水平均升高,且观察组高于对照组(P<0.05)。结论:将传统综合疗法及VTS4疗法应用于屈光不正性弱视患儿,可改善视功能,提高视力水平及眼调节功能,临床疗效好。

基于哈特曼探测器的光波相位三维显示方法

相位是描述光波状态的重要参数,但却无法直接观察。本文基于哈特曼探测器的波前快速探测功能,研究了光波相位三维显示的方法,并研制出相位三维显示系统。首先,利用Zemax软件对系统的光源、准直透镜等光学参数进行优化设计;然后,基于模式法波前重构理论,根据探测的Zernike多项式离焦量和像散项系数,实现了对3个不同类型镜片的相位三维显示,并给出相应屈光度的测量方法;最后,实验验证了光波相位的三维显示和屈光度测量的有效性,-2.00 D的近视镜测量值为-2.07 D,1.00 D的远视镜测量值为0.91 D,0.50 D的散光镜测量值为0.56 D。实验结果表明,此系统能够较准确地测量屈光矫正镜的屈光度,并实现相位的三维显示。本文设计的基于哈特曼探测器的相位三维显示方法具有更好的环境适应能力,便于研究者直观观测光的相位分布。

多媒体视觉生理刺激联合立体系统训练治疗屈光不正性弱视

目的:分析多媒体视觉生理刺激联合立体系统训练治疗屈光不正性弱视儿童的疗效。方法:选取2021-06/2022-06本院收治的屈光不正性弱视患儿102例102眼,随机分组,对照组患儿51例51眼在常规治疗基础上采用多媒体视觉生理刺激治疗,观察组患儿51例51眼在对照组基础上联合采用立体系统训练治疗。治疗后3mo,评估两组患儿双眼融象功能、双眼立体视、双眼立体视差,并根据视力改善情况评估临床疗效。结果:治疗后3mo,观察组患儿双眼融象功能、双眼立体视、双眼立体视差正常率均明显高于对照组(均P<0.05),观察组患儿治疗总有效率明显高于对照组(94.1%vs 60.8%,P<0.05),且观察组中不同年龄患儿治疗总有效率均高于对照组(P<0.05),其中6~8岁患儿治疗总有效率最高;观察组中轻中度弱视患儿治疗总有效率高于对照组(94.0%vs 61.2%,P<0.05)。结论:多媒体视觉生理刺激联合立体系统训练治疗屈光不正性弱视疗效较好,可促进患儿视力恢复,帮助重建双眼立体视觉功能,且对6~8岁及轻中度弱视患儿效果更好。

近视性屈光不正和眼生物测量参数与糖尿病视网膜病变相关性研究进展

糖尿病视网膜病变(DR)是导致患者视力损害和失明的主要原因之一。已有研究表明,近视和随近视增长的眼轴长度(AL)可能是防止DR发生发展的保护因素,但研究结果并不一致,且尚不清楚起保护作用的是哪种屈光参数。本文通过回顾近年来文献对近视性屈光不正状态、AL、前房深度、角膜曲率、晶状体度数等相关眼生物测量参数与DR相关性的研究进展和可能的保护机制作一综述。