The paper studies the chemical structures of eight synthetic 9-β-D-xylofuranosyl-adenine-8-subatituted amino derivatives,by Fast Atom Bombardment Mass Spectrometry(FAB-MS).FAB-MS spectrum can give the molecular weigh...The paper studies the chemical structures of eight synthetic 9-β-D-xylofuranosyl-adenine-8-subatituted amino derivatives,by Fast Atom Bombardment Mass Spectrometry(FAB-MS).FAB-MS spectrum can give the molecular weight information of the samples and inquire into the significant fragments from the samples.展开更多
Amphioxus in the seasonally regressed phase of gonadat development were used in this study. Each sample animal was injected with 40 nanogram of synthetic gonadotropin-releasing hormone analogue (GnRH-A) in distilled w...Amphioxus in the seasonally regressed phase of gonadat development were used in this study. Each sample animal was injected with 40 nanogram of synthetic gonadotropin-releasing hormone analogue (GnRH-A) in distilled water every other day for up to 16 days; control animals received similar volumes of distilled wnter only. Both hormone-treated samples and control animals were examined under microscope every eight days and every twelve days. Then all the animals were killed on the 16th day. Gonads earlier development and a more advanced degree of gametogenesis are in the hormone-treated group than in the control group. Thus, GnRH-A can initiate and accelerate the gonadal development in gonadally regressed am-phioxus. GnRH-A in some form may be important in regulating the gonadal development in amphioxus as well as in vertebrates.展开更多
文摘The paper studies the chemical structures of eight synthetic 9-β-D-xylofuranosyl-adenine-8-subatituted amino derivatives,by Fast Atom Bombardment Mass Spectrometry(FAB-MS).FAB-MS spectrum can give the molecular weight information of the samples and inquire into the significant fragments from the samples.
基金This work is supported by the foundation of the National natural Science
文摘Amphioxus in the seasonally regressed phase of gonadat development were used in this study. Each sample animal was injected with 40 nanogram of synthetic gonadotropin-releasing hormone analogue (GnRH-A) in distilled water every other day for up to 16 days; control animals received similar volumes of distilled wnter only. Both hormone-treated samples and control animals were examined under microscope every eight days and every twelve days. Then all the animals were killed on the 16th day. Gonads earlier development and a more advanced degree of gametogenesis are in the hormone-treated group than in the control group. Thus, GnRH-A can initiate and accelerate the gonadal development in gonadally regressed am-phioxus. GnRH-A in some form may be important in regulating the gonadal development in amphioxus as well as in vertebrates.