Based on the transfer matrix method and the virtual source simulation technique, this paper proposes a novel semi-analytical and semi-numerical method for solving 2-D sound- structure interaction problems under a harm...Based on the transfer matrix method and the virtual source simulation technique, this paper proposes a novel semi-analytical and semi-numerical method for solving 2-D sound- structure interaction problems under a harmonic excitation.Within any integration segment, as long as its length is small enough,along the circumferential curvilinear coordinate,the non- homogeneous matrix differential equation of an elastic ring of complex geometrical shape can be rewritten in terms of the homogeneous one by the method of extended homogeneous capacity proposed in this paper.For the exterior fluid domain,the multi-circular virtual source simulation technique is adopted.The source density distributed on each virtual circular curve may be ex- panded as the Fourier's series.Combining with the inverse fast Fourier transformation,a higher accuracy and efficiency method for solving 2-D exterior Helmholtz's problems is presented in this paper.In the aspect of solution to the coupling equations,the state vectors of elastic ring induced by the given harmonic excitation and generalized forces of coefficients of the Fourier series can be obtained respectively by using a high precision integration scheme combined with the method of extended homogeneous capacity put forward in this paper.According to the superposition princi- ple and compatibility conditions at the interface between the elastic ring and fluid,the algebraic equation of system can be directly constructed by using the least square approximation.Examples of acoustic radiation from two typical fluid-loaded elastic rings under a harmonic concentrated force are presented.Numerical results show that the method proposed is more efficient than the mixed FE-BE method in common use.展开更多
Based on the extended homogeneous capacity high precision integration method and the spectrum method of virtual boundary with a complex radius vector, a novel semi-analytical method, which has satisfactory computation...Based on the extended homogeneous capacity high precision integration method and the spectrum method of virtual boundary with a complex radius vector, a novel semi-analytical method, which has satisfactory computation efectiveness and precision, is presented for solving the acoustic radiation from a submerged infnite non-circular cylindrical shell stifened by longitudinal ribs by means of the Fourier integral transformation and stationary phase method. In this work, besides the normal interacting force, which is commonly adopted by some researchers, the other interacting forces and moments between the longitudinal ribs and the non-circular cylindrical shell are considered at the same time. The efects of the number and the size of the cross-section of longitudinal ribs on the characteristics of acoustic radiation are investigated. Numerical results show that the method proposed is more efcient than the existing mixed FE-BE method.展开更多
The effect of axial shallow groove on the nonlinear dynamic response and buckling of laminated cylindrical shells subjected to radial compression loading was investigated. Based on the first-order shear deformation th...The effect of axial shallow groove on the nonlinear dynamic response and buckling of laminated cylindrical shells subjected to radial compression loading was investigated. Based on the first-order shear deformation theory (FSDT), the nonlinear dynamic equations involving the transverse shear deformation and initial geometric imperfections were derived with the Hamilton philosophy. The axial shallow groove of the laminated composite cylindrical shell was treated as the initial geometric imperfections in the dynamic equations. A semi-analytical method of expanding displacements and loads along the circumferential direction and employing the finite difference method along the axial direction and in the time domain is used to solve the governing equations and obtain the dynamic response of the laminated shell. The B-R criterion was employed to determine the critical loads of dynamic buckling of the shell. The effects of the parameters of the shallow groove on the dynamic response and buckling were discussed in this paper and the results show that the axial shallow grooves greatly affect the dynamic response and buckling.展开更多
A semi-analytical and semi-numerical method is proposed for the dynamic analysis of foundations. The Lamb's solution and the approximate formulae were used to establish the relation of the contact force and deflectio...A semi-analytical and semi-numerical method is proposed for the dynamic analysis of foundations. The Lamb's solution and the approximate formulae were used to establish the relation of the contact force and deflection between the foundation and soil. Therefore, the foundation can be separated from soil and analyzed by FEM as for the static cases. The plate can be treated as that the known forces are acting on the upper surface, and the contact pressure from soil can be represented as the deflection. So that only the plate needs to be divided into elements in the analysis. By this method, a series of vibration problems, including various shapes and rigidities of foundations, different excitation frequencies, were analyzed. Furthermore, it can be used for the embedded foundation. The numerical examples show that this method has simplicity, highly accurate and versatile. It is an effective method for the dynamic analysis of foundations.展开更多
Based on the Hamiltonian governing equations of plane elasticity for sectorial domain, the variable separation and eigenfunction expansion techniques were employed to develop a novel analytical finite element for the ...Based on the Hamiltonian governing equations of plane elasticity for sectorial domain, the variable separation and eigenfunction expansion techniques were employed to develop a novel analytical finite element for the fictitious crack model in fracture mechanics of concrete. The new analytical element can be implemented into FEM program systems to solve fictitious crack propagation problems for concrete cracked plates with arbitrary shapes and loads. Numerical results indicate that the method is more efficient and accurate than ordinary finite element method.展开更多
Motion responses of two ships advancing parallel in waves with hydrodynamic interactions are investigated in this paper. Within the framework of the frequency-domain potential flow theory, a semi-analytical higher-ord...Motion responses of two ships advancing parallel in waves with hydrodynamic interactions are investigated in this paper. Within the framework of the frequency-domain potential flow theory, a semi-analytical higher-order translating-pulsating source(HOTP) method is presented to solve the problems of coupled radiation and diffraction potential. The method employs nine-node bi-quadratic curvilinear elements to discretize the boundary integral equations(BIEs) constructed over the mean wetted surface of the two ship hulls. In order to eliminate the numerical oscillation, analytical quadrature formulas are derived and adopted to evaluate the integrals related to the Froudedependent part of the Green’s function along the horizontal direction in the BIEs. Based on the method, a numerical program is originally coded. Through the calculations of hydrodynamic responses of single ships, the numerical implementation is proved successful. Then the validated program is applied in the investigations on the hydrodynamic interactions of two identical Wigley Ⅲ hulls and the underway replenishment of a frigate and a supply ship in waves with and without stagger, respectively. The comparison between the present computed results with experimental data and numerical solutions of other methods shows that the semi-analytical HOTP method is of higher accuracy than the pulsating source Green’s function method with speed correction and better stability than the traditional HOTP method based on Gauss quadrature. In addition, for two ships with obviously different dimensions,the influence of hydrodynamic interactions on the smaller ship is found to be more noticeable than that on the larger ship, which leads to the differences between the motions of frigate with and without the presence of supply ship.展开更多
The chiral nature of biological systems enables their stereoselective interaction with chiral compounds. It has been well documented that the enantiomers ofa chiral drug may show differences in drug disposition especi...The chiral nature of biological systems enables their stereoselective interaction with chiral compounds. It has been well documented that the enantiomers ofa chiral drug may show differences in drug disposition especially in metabolic behavior. As a result, it is of vital importance to separate the enantiomers of a chiral drug in metabolic studies. This paper discusses enantioselective methods (include high-performance liquid chromatography, gas chromatography, capillary electrophoresis and high-performance liquid chromatography-mass spectrometry) that applied in chiral drug metabolism, using most recent examples where possible.展开更多
The layout forms of several breakwater structures can be generalized as asymmetrical arrangements in actual engineering.However,the problem of wave diffraction around asymmetrically arranged breakwaters has not been a...The layout forms of several breakwater structures can be generalized as asymmetrical arrangements in actual engineering.However,the problem of wave diffraction around asymmetrically arranged breakwaters has not been adequately investigated.In this study,we propose an analytical method of wave diffraction for regular waves passing through asymmetrically arranged breakwaters,and we use the Nyström method to obtain the analytical solution numerically.We compared the results of this method with those of previous analytical solutions and with numerical results to demonstrate the validity of our approach.We also provided diffraction coefficient diagrams of breakwaters with different layout forms.Moreover,we described the analytical expression for the problem of diffraction through long-wave incident breakwaters and presented an analysis of the relationship between the diffraction coefficients and the widths of breakwater gates.The analytical method presented in this study contributes to the limited literature on the theory of wave diffraction through asymmetrically arranged breakwaters.展开更多
A versatile analytical method(VAM) for calculating the harmonic components of the magnetomotive force(MMF) generated by diverse armature windings in AC machines has been proposed, and the versatility of this method ha...A versatile analytical method(VAM) for calculating the harmonic components of the magnetomotive force(MMF) generated by diverse armature windings in AC machines has been proposed, and the versatility of this method has been established in early literature. However, its practical applications and significance in advancing the analysis of AC machines need further elaboration. This paper aims to complement VAM by augmenting its theory, offering additional insights into its conclusions, as well as demonstrating its utility in assessing armature windings and its application of calculating torque for permanent magnet synchronous machines(PMSM). This work contributes to advancing the analysis of AC machines and underscores the potential for improved design and performance optimization.展开更多
The Laguerre polynomial method has been successfully used to investigate the dynamic responses of a half-space.However,it fails to obtain the correct stress at the interfaces in a layered half-space,especially when th...The Laguerre polynomial method has been successfully used to investigate the dynamic responses of a half-space.However,it fails to obtain the correct stress at the interfaces in a layered half-space,especially when there are significant differences in material properties.Therefore,a coupled Legendre-Laguerre polynomial method with analytical integration is proposed.The Rayleigh waves in a one-dimensional(1D)hexagonal quasicrystal(QC)layered half-space with an imperfect interface are investigated.The correctness is validated by comparison with available results.Its computation efficiency is analyzed.The dispersion curves of the phase velocity,displacement distributions,and stress distributions are illustrated.The effects of the phonon-phason coupling and imperfect interface coefficients on the wave characteristics are investigated.Some novel findings reveal that the proposed method is highly efficient for addressing the Rayleigh waves in a QC layered half-space.It can save over 99%of the computation time.This method can be expanded to investigate waves in various layered half-spaces,including earth-layered media and surface acoustic wave(SAW)devices.展开更多
In the present work, the different sample collection, pretreatment and analytical methods for polycyclic aromatic hydrocarbons (PAHs) in airborne particulates is systematacially reviewed, and the applications of the...In the present work, the different sample collection, pretreatment and analytical methods for polycyclic aromatic hydrocarbons (PAHs) in airborne particulates is systematacially reviewed, and the applications of these pretreatment and analytical methods for PAHs are compared in detail. Some comments on the future expectation are also presented.展开更多
A differential equation of first order can be expressed by the equation of motion of a mechanical system. In this paper, three methods of analytical mechanics, i.e. the Hamilton-Noether method, the Lagrange-Noether me...A differential equation of first order can be expressed by the equation of motion of a mechanical system. In this paper, three methods of analytical mechanics, i.e. the Hamilton-Noether method, the Lagrange-Noether method and the Poisson method, are given to solve a differential equation of first order, of which the way may be called the mechanical methodology in mathematics.展开更多
Nanoliposomes are considered to be the most successful nanoparticle drug delivery system, but their fate in vivo has not been fully understood due to lack of reliable bioanalytical methods, which seriously limits the ...Nanoliposomes are considered to be the most successful nanoparticle drug delivery system, but their fate in vivo has not been fully understood due to lack of reliable bioanalytical methods, which seriously limits the development of liposomal drugs. Hence, an overview of currently used bioanalytical methods is imperative to lay the groundwork for the need of developing a bioanalytical method for liposome measurements in vivo. Currently, major analytical methods for nanoliposomes measurement in vivo include fluorescence labeling, radiolabeling, magnetic resonance imaging(MRI), mass spectrometry and computed tomography. In this review, these bioanalytical methods are summarized, and the advantages and disadvantages of each are discussed. We provide insights into the applicability and limitations of these analytical methods in the application of nanoliposomes measurement in vivo, and highlight the recent development of instrumental analysis techniques. The review is devoted to providing a comprehensive overview of the investigation of nanoliposomes design and associated fate in vivo, promoting the development of bioanalytical techniques for nanoliposomes measurement, and understanding the pharmacokinetic behavior, effectiveness and potential toxicity of nanoliposomes in vivo.展开更多
Terbinafine is a new powerful antifungal agent indicated for both oral and topical treatment of myco- sessince. It is highly effective in the treatment of determatomycoses. The chemical and pharmaceutical analysis of ...Terbinafine is a new powerful antifungal agent indicated for both oral and topical treatment of myco- sessince. It is highly effective in the treatment of determatomycoses. The chemical and pharmaceutical analysis of the drug requires effective analytical methods for quality control and pharmacodynamic and pharmacokinetic studies. Ever since it was introduced as an effective antifungal agent, many methods have been developed and validated for its assay in pharmaceuticals and biological materials. This article reviews the various methods reported during the last 25 years.展开更多
Assessment of acid sulfate soil risk is an important step for acid sulfate soil management and its reliability depends very much on the suitability and accuracy of various analytical methods for estimating sulfide-der...Assessment of acid sulfate soil risk is an important step for acid sulfate soil management and its reliability depends very much on the suitability and accuracy of various analytical methods for estimating sulfide-derived potential acidity, actual acidity and acid-neutralizing capacity in acid sulfate soils. This paper critically reviews various analytical methods that are currently used for determination of the above parameters, as well as their implications for environmental risk assessment of acid sulfate soi1s.展开更多
Pioglitazone is an oral anti-hyperglycemic agent. It is used for the treatment of diabetes mellitus type 2. It selectively stimulates nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR-gamma). I...Pioglitazone is an oral anti-hyperglycemic agent. It is used for the treatment of diabetes mellitus type 2. It selectively stimulates nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR-gamma). It was the tenth-best-selling drug in the U.S. in 2008. This article examines published analytical methods reported so far in the literature for the determination of pioglitazone in biological samples and pharmaceutical formulations. They include various techniques like electrochemical methods, spectrophotometry, capillary electrophoresis, high-performance liquid chromatography, liquid chromatography-electrospray ionization-tandem mass spectrometry and high-performance thin layer chromatography.展开更多
Semi-analytical elasticity solutions for bending of angle-ply laminates in cylindrical bending are presented using the state-space-based differential quadrature method (SSDQM). Partial differential state equation is d...Semi-analytical elasticity solutions for bending of angle-ply laminates in cylindrical bending are presented using the state-space-based differential quadrature method (SSDQM). Partial differential state equation is derived from the basic equations of elasticity based on the state space concept. Then, the differential quadrature (DQ) technique is introduced to discretize the longitu- dinal domain of the plate so that a series of ordinary differential state equations are obtained at the discrete points. Meanwhile, the edge constrained conditions are handled directly using the stress and displacement components without the Saint-Venant principle. The thickness domain is solved analytically based on the state space formalism along with the continuity conditions at interfaces. The present method is validated by comparing the results to the exact solutions of Pagano’s problem. Numerical results for fully clamped thick laminates are presented, and the influences of ply angle on stress distributions are discussed.展开更多
The purpose of this study was to investigate the effect of bolt profile on load transfer mechanism of fully grouted bolts in jointed rocks using analytical and numerical methods. Based on the analytical method with de...The purpose of this study was to investigate the effect of bolt profile on load transfer mechanism of fully grouted bolts in jointed rocks using analytical and numerical methods. Based on the analytical method with development of methods, a new model is presented. To validate the analytical model, five different profiles modeled by ANSYS software. The profile of rock bolts T3 and T4with load transfer capacity,respectively 180 and 195 kN in the jointed rocks was selected as the optimum profiles. Finally, the selected profiles were examined in Tabas Coal Mine. FLAC analysis indicates that patterns 6+7 with2 NO flexi bolt 4 m better than other patterns within the faulted zone.展开更多
4 semi-analytical approach for the dynamic response of general thin plates whichemployes finite element discretization in space domain and a series of representation intime demain is developed on the basis of Curtin v...4 semi-analytical approach for the dynamic response of general thin plates whichemployes finite element discretization in space domain and a series of representation intime demain is developed on the basis of Curtin variational principles.The formulationof time series is also investigated so that the dynamic response of plates with arbitraryshape and boundary constraints can be achieved with adequate accuracy.展开更多
基金Project supported by the National Natural Science Foundation of China (No.10172038)
文摘Based on the transfer matrix method and the virtual source simulation technique, this paper proposes a novel semi-analytical and semi-numerical method for solving 2-D sound- structure interaction problems under a harmonic excitation.Within any integration segment, as long as its length is small enough,along the circumferential curvilinear coordinate,the non- homogeneous matrix differential equation of an elastic ring of complex geometrical shape can be rewritten in terms of the homogeneous one by the method of extended homogeneous capacity proposed in this paper.For the exterior fluid domain,the multi-circular virtual source simulation technique is adopted.The source density distributed on each virtual circular curve may be ex- panded as the Fourier's series.Combining with the inverse fast Fourier transformation,a higher accuracy and efficiency method for solving 2-D exterior Helmholtz's problems is presented in this paper.In the aspect of solution to the coupling equations,the state vectors of elastic ring induced by the given harmonic excitation and generalized forces of coefficients of the Fourier series can be obtained respectively by using a high precision integration scheme combined with the method of extended homogeneous capacity put forward in this paper.According to the superposition princi- ple and compatibility conditions at the interface between the elastic ring and fluid,the algebraic equation of system can be directly constructed by using the least square approximation.Examples of acoustic radiation from two typical fluid-loaded elastic rings under a harmonic concentrated force are presented.Numerical results show that the method proposed is more efficient than the mixed FE-BE method in common use.
基金Project supported by the National Natural Science Foundation of China(No.10172038),the Doctoral Foundation ofthe National Education Ministry(No.20040487013)and the Natural Science Foundation of Guangxi(No.0339019).
文摘Based on the extended homogeneous capacity high precision integration method and the spectrum method of virtual boundary with a complex radius vector, a novel semi-analytical method, which has satisfactory computation efectiveness and precision, is presented for solving the acoustic radiation from a submerged infnite non-circular cylindrical shell stifened by longitudinal ribs by means of the Fourier integral transformation and stationary phase method. In this work, besides the normal interacting force, which is commonly adopted by some researchers, the other interacting forces and moments between the longitudinal ribs and the non-circular cylindrical shell are considered at the same time. The efects of the number and the size of the cross-section of longitudinal ribs on the characteristics of acoustic radiation are investigated. Numerical results show that the method proposed is more efcient than the existing mixed FE-BE method.
基金Project supported by the National Natural Science Foundation of China (Grant No. 10202013)
文摘The effect of axial shallow groove on the nonlinear dynamic response and buckling of laminated cylindrical shells subjected to radial compression loading was investigated. Based on the first-order shear deformation theory (FSDT), the nonlinear dynamic equations involving the transverse shear deformation and initial geometric imperfections were derived with the Hamilton philosophy. The axial shallow groove of the laminated composite cylindrical shell was treated as the initial geometric imperfections in the dynamic equations. A semi-analytical method of expanding displacements and loads along the circumferential direction and employing the finite difference method along the axial direction and in the time domain is used to solve the governing equations and obtain the dynamic response of the laminated shell. The B-R criterion was employed to determine the critical loads of dynamic buckling of the shell. The effects of the parameters of the shallow groove on the dynamic response and buckling were discussed in this paper and the results show that the axial shallow grooves greatly affect the dynamic response and buckling.
文摘A semi-analytical and semi-numerical method is proposed for the dynamic analysis of foundations. The Lamb's solution and the approximate formulae were used to establish the relation of the contact force and deflection between the foundation and soil. Therefore, the foundation can be separated from soil and analyzed by FEM as for the static cases. The plate can be treated as that the known forces are acting on the upper surface, and the contact pressure from soil can be represented as the deflection. So that only the plate needs to be divided into elements in the analysis. By this method, a series of vibration problems, including various shapes and rigidities of foundations, different excitation frequencies, were analyzed. Furthermore, it can be used for the embedded foundation. The numerical examples show that this method has simplicity, highly accurate and versatile. It is an effective method for the dynamic analysis of foundations.
文摘Based on the Hamiltonian governing equations of plane elasticity for sectorial domain, the variable separation and eigenfunction expansion techniques were employed to develop a novel analytical finite element for the fictitious crack model in fracture mechanics of concrete. The new analytical element can be implemented into FEM program systems to solve fictitious crack propagation problems for concrete cracked plates with arbitrary shapes and loads. Numerical results indicate that the method is more efficient and accurate than ordinary finite element method.
基金This work was financially supported by the National Natural Science Foundation of China(Grant No.52101357)the Natural Science Foundation of the Jiangsu Higher Education Institutions of China(Grant No.21KJB580012)the Scientific Research Start-up Fund of Jiangsu University of Science and Technology.
文摘Motion responses of two ships advancing parallel in waves with hydrodynamic interactions are investigated in this paper. Within the framework of the frequency-domain potential flow theory, a semi-analytical higher-order translating-pulsating source(HOTP) method is presented to solve the problems of coupled radiation and diffraction potential. The method employs nine-node bi-quadratic curvilinear elements to discretize the boundary integral equations(BIEs) constructed over the mean wetted surface of the two ship hulls. In order to eliminate the numerical oscillation, analytical quadrature formulas are derived and adopted to evaluate the integrals related to the Froudedependent part of the Green’s function along the horizontal direction in the BIEs. Based on the method, a numerical program is originally coded. Through the calculations of hydrodynamic responses of single ships, the numerical implementation is proved successful. Then the validated program is applied in the investigations on the hydrodynamic interactions of two identical Wigley Ⅲ hulls and the underway replenishment of a frigate and a supply ship in waves with and without stagger, respectively. The comparison between the present computed results with experimental data and numerical solutions of other methods shows that the semi-analytical HOTP method is of higher accuracy than the pulsating source Green’s function method with speed correction and better stability than the traditional HOTP method based on Gauss quadrature. In addition, for two ships with obviously different dimensions,the influence of hydrodynamic interactions on the smaller ship is found to be more noticeable than that on the larger ship, which leads to the differences between the motions of frigate with and without the presence of supply ship.
基金National Natural Science Foundation of China(Grant No.30225047 and 30701038)
文摘The chiral nature of biological systems enables their stereoselective interaction with chiral compounds. It has been well documented that the enantiomers ofa chiral drug may show differences in drug disposition especially in metabolic behavior. As a result, it is of vital importance to separate the enantiomers of a chiral drug in metabolic studies. This paper discusses enantioselective methods (include high-performance liquid chromatography, gas chromatography, capillary electrophoresis and high-performance liquid chromatography-mass spectrometry) that applied in chiral drug metabolism, using most recent examples where possible.
基金supported by the National Natural Science Foundation of China(Grant No.51679132)the Science and Technology Commission of Shanghai Municipality(Grant No.21ZR1427000)Shanghai Frontiers Science Center of“Full Penetration”Far-Reaching Offshore Ocean Energy and Power.
文摘The layout forms of several breakwater structures can be generalized as asymmetrical arrangements in actual engineering.However,the problem of wave diffraction around asymmetrically arranged breakwaters has not been adequately investigated.In this study,we propose an analytical method of wave diffraction for regular waves passing through asymmetrically arranged breakwaters,and we use the Nyström method to obtain the analytical solution numerically.We compared the results of this method with those of previous analytical solutions and with numerical results to demonstrate the validity of our approach.We also provided diffraction coefficient diagrams of breakwaters with different layout forms.Moreover,we described the analytical expression for the problem of diffraction through long-wave incident breakwaters and presented an analysis of the relationship between the diffraction coefficients and the widths of breakwater gates.The analytical method presented in this study contributes to the limited literature on the theory of wave diffraction through asymmetrically arranged breakwaters.
基金supported by the Natural Science Foundation of China under Grant U22A20214 and Grant 51837010。
文摘A versatile analytical method(VAM) for calculating the harmonic components of the magnetomotive force(MMF) generated by diverse armature windings in AC machines has been proposed, and the versatility of this method has been established in early literature. However, its practical applications and significance in advancing the analysis of AC machines need further elaboration. This paper aims to complement VAM by augmenting its theory, offering additional insights into its conclusions, as well as demonstrating its utility in assessing armature windings and its application of calculating torque for permanent magnet synchronous machines(PMSM). This work contributes to advancing the analysis of AC machines and underscores the potential for improved design and performance optimization.
基金Project supported by the National Natural Science Foundation of China(No.12102131)the Natural Science Foundation of Henan Province of China(No.242300420248)the International Science and Technology Cooperation Project of Henan Province of China(No.242102521010)。
文摘The Laguerre polynomial method has been successfully used to investigate the dynamic responses of a half-space.However,it fails to obtain the correct stress at the interfaces in a layered half-space,especially when there are significant differences in material properties.Therefore,a coupled Legendre-Laguerre polynomial method with analytical integration is proposed.The Rayleigh waves in a one-dimensional(1D)hexagonal quasicrystal(QC)layered half-space with an imperfect interface are investigated.The correctness is validated by comparison with available results.Its computation efficiency is analyzed.The dispersion curves of the phase velocity,displacement distributions,and stress distributions are illustrated.The effects of the phonon-phason coupling and imperfect interface coefficients on the wave characteristics are investigated.Some novel findings reveal that the proposed method is highly efficient for addressing the Rayleigh waves in a QC layered half-space.It can save over 99%of the computation time.This method can be expanded to investigate waves in various layered half-spaces,including earth-layered media and surface acoustic wave(SAW)devices.
基金Project supported by the National Natural Science Foundation of China (No. 20437020 20575073) NSFC-JSPS Joint Research Project (No. 20511140134) the Major Research Program of Chinese Academy of Sciences (KZCX3-SW-432)
文摘In the present work, the different sample collection, pretreatment and analytical methods for polycyclic aromatic hydrocarbons (PAHs) in airborne particulates is systematacially reviewed, and the applications of these pretreatment and analytical methods for PAHs are compared in detail. Some comments on the future expectation are also presented.
基金Project supported by the National Natural Science Foundation of China (Grant No 10272021) and the Doctorate Foundation of the State Education Ministry of China (Grant No 20040007022).
文摘A differential equation of first order can be expressed by the equation of motion of a mechanical system. In this paper, three methods of analytical mechanics, i.e. the Hamilton-Noether method, the Lagrange-Noether method and the Poisson method, are given to solve a differential equation of first order, of which the way may be called the mechanical methodology in mathematics.
基金supported by the National Natural Science Foundation of China (Grant No. 81430087, 81673396, 81603182)
文摘Nanoliposomes are considered to be the most successful nanoparticle drug delivery system, but their fate in vivo has not been fully understood due to lack of reliable bioanalytical methods, which seriously limits the development of liposomal drugs. Hence, an overview of currently used bioanalytical methods is imperative to lay the groundwork for the need of developing a bioanalytical method for liposome measurements in vivo. Currently, major analytical methods for nanoliposomes measurement in vivo include fluorescence labeling, radiolabeling, magnetic resonance imaging(MRI), mass spectrometry and computed tomography. In this review, these bioanalytical methods are summarized, and the advantages and disadvantages of each are discussed. We provide insights into the applicability and limitations of these analytical methods in the application of nanoliposomes measurement in vivo, and highlight the recent development of instrumental analysis techniques. The review is devoted to providing a comprehensive overview of the investigation of nanoliposomes design and associated fate in vivo, promoting the development of bioanalytical techniques for nanoliposomes measurement, and understanding the pharmacokinetic behavior, effectiveness and potential toxicity of nanoliposomes in vivo.
文摘Terbinafine is a new powerful antifungal agent indicated for both oral and topical treatment of myco- sessince. It is highly effective in the treatment of determatomycoses. The chemical and pharmaceutical analysis of the drug requires effective analytical methods for quality control and pharmacodynamic and pharmacokinetic studies. Ever since it was introduced as an effective antifungal agent, many methods have been developed and validated for its assay in pharmaceuticals and biological materials. This article reviews the various methods reported during the last 25 years.
文摘Assessment of acid sulfate soil risk is an important step for acid sulfate soil management and its reliability depends very much on the suitability and accuracy of various analytical methods for estimating sulfide-derived potential acidity, actual acidity and acid-neutralizing capacity in acid sulfate soils. This paper critically reviews various analytical methods that are currently used for determination of the above parameters, as well as their implications for environmental risk assessment of acid sulfate soi1s.
文摘Pioglitazone is an oral anti-hyperglycemic agent. It is used for the treatment of diabetes mellitus type 2. It selectively stimulates nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR-gamma). It was the tenth-best-selling drug in the U.S. in 2008. This article examines published analytical methods reported so far in the literature for the determination of pioglitazone in biological samples and pharmaceutical formulations. They include various techniques like electrochemical methods, spectrophotometry, capillary electrophoresis, high-performance liquid chromatography, liquid chromatography-electrospray ionization-tandem mass spectrometry and high-performance thin layer chromatography.
基金Project supported by the National Natural Science Foundation of China (No. 10432030)the China Postdoctoral Science Foundation (No. 20060401071)the Program for New Century Excellent Talent in University of China (No. NCET-05-0510)
文摘Semi-analytical elasticity solutions for bending of angle-ply laminates in cylindrical bending are presented using the state-space-based differential quadrature method (SSDQM). Partial differential state equation is derived from the basic equations of elasticity based on the state space concept. Then, the differential quadrature (DQ) technique is introduced to discretize the longitu- dinal domain of the plate so that a series of ordinary differential state equations are obtained at the discrete points. Meanwhile, the edge constrained conditions are handled directly using the stress and displacement components without the Saint-Venant principle. The thickness domain is solved analytically based on the state space formalism along with the continuity conditions at interfaces. The present method is validated by comparing the results to the exact solutions of Pagano’s problem. Numerical results for fully clamped thick laminates are presented, and the influences of ply angle on stress distributions are discussed.
文摘The purpose of this study was to investigate the effect of bolt profile on load transfer mechanism of fully grouted bolts in jointed rocks using analytical and numerical methods. Based on the analytical method with development of methods, a new model is presented. To validate the analytical model, five different profiles modeled by ANSYS software. The profile of rock bolts T3 and T4with load transfer capacity,respectively 180 and 195 kN in the jointed rocks was selected as the optimum profiles. Finally, the selected profiles were examined in Tabas Coal Mine. FLAC analysis indicates that patterns 6+7 with2 NO flexi bolt 4 m better than other patterns within the faulted zone.
文摘4 semi-analytical approach for the dynamic response of general thin plates whichemployes finite element discretization in space domain and a series of representation intime demain is developed on the basis of Curtin variational principles.The formulationof time series is also investigated so that the dynamic response of plates with arbitraryshape and boundary constraints can be achieved with adequate accuracy.