[Objectives]Through data mining and analysis,the medication characters and ideas of ye Tianshi,a famous physician in Qing Dynasty,in the treatment of tinnitus were explored,so as to provide reference for clinical tinn...[Objectives]Through data mining and analysis,the medication characters and ideas of ye Tianshi,a famous physician in Qing Dynasty,in the treatment of tinnitus were explored,so as to provide reference for clinical tinnitus treatment.[Methods]The medical records of Ye Tianshi's treatment of tinnitus in the Ancient and Modern Consilia Cloud Platform were retrieved and sorted,and the use frequency,properties,metabolic organ and compatibility of related Chinese herbs in the cases were analyzed through system-integrated statistical analysis,cluster analysis,association rules analysis and complex network analysis.[Results]A total of 46 medical cases were finally included,with 15 frequently used Chinese herbs,including poria with hostwood,Radix Rehmanniae Preparata,magnetitum,etc.Most of the drugs are cold and neutral in nature,sweet and bitter in taste,and metabolized in liver and heart.The results of cluster analysis show that the therapeutic drugs for tinnitus are mainly divided into four categories:strengthening spleen,nourishing yin,suppressing symptoms,and clearing heat.The results of association rules analysis show that the commonly used traditional Chinese medicine combination is composed of three herbs,poria with hostwood,Radix Ophiopogonis,and Radix et Rhizoma Glycyrrhizae,which have spleen-strengthening and stomach-tonifying effects.The results of complex network analysis show that the core prescription is based on Siwu Decoction.[Conclusions]In the treatment of tinnitus,Ye Tianshi paid attention to the three internal organs of heart,kidney and gallbladder,and made good use of lung qi-dispersing drugs to clear heat,sweet and cold drugs to tonify stomach and nourish yin,and tonic drugs to suppress symptoms.The core prescription is mainly composed of Radix Rehmanniae,Radix Rehmanniae Preparata,oyster,poria with hostwood,Fructus Forsythiae,Radix Paeoniae Alba,antelope horn,magnetitum and Radix Asparagi.The commonly used single herbs are poria with hostwood,Radix Rehmanniae Preparata and magnetitum.The combination of poria with hostwood,Radix Ophiopogonis and Radix et Rhizoma Glycyrrhizae is more common.展开更多
Nancient times, is the capitalcity of Jiangsu Province atthe lower reaches of the Changjiang(Yangtze River).Its beautiful landscapehas attracted rulers and men of letterssince place for learned people in southChina an...Nancient times, is the capitalcity of Jiangsu Province atthe lower reaches of the Changjiang(Yangtze River).Its beautiful landscapehas attracted rulers and men of letterssince place for learned people in southChina and the territory of monarchs."Its ancient heritage and natural envi-ronment have now become valuableresources of local tourism.During a period of 2,600 years,Nanjing served as the capital city ofthe Eastern wu Dynasty of the ThreeKingdoms Period,the Eastern Jin Dy-nasty,the Southern Dynasties,theSouthern Tang,the Early Ming,theTaiping Heavenly Kingdom and theRepublic of China,leaving behind展开更多
Epidemic diseases,known and studied in China since antiquity,are one of the main chapters of the School of Exogenous Febrile Diseases(温病学派)•Along with the legends about epidemic demons,China has developed over the...Epidemic diseases,known and studied in China since antiquity,are one of the main chapters of the School of Exogenous Febrile Diseases(温病学派)•Along with the legends about epidemic demons,China has developed over the centuries a medical approach based on the teachings of Huang Di Nei Jing(《黄帝内经》Internal Classic),Nan Jing(《难经》Classic of Difficulties'),and Shang Han Lun(《伤寒论》Treatise of Harmful Cold).However,it was in the 17th century,after the great break of the Song,Jin,and Yuan eras that an innovative spirit Wu Youxing(吴有性)first foresaw the existence of microorganisms as we know them now.His Wen Yi Lun(《瘟疫论》Treatise on Pestilences)foreshadows an original approach to epidemic diseases,particularly emerging infectious diseases of the 21st century:severe acute respiratory syndrome 2003-2004 and the COVID-19 pandemic are perfect examples.In this first article,which will be followed by two others,we will examine the classical and modern Chinese definitions of these dreadful plagues.展开更多
Objective:This study analyzed the data of the medical cases in the book,“Clinical Guide Medical records”using a data mining method,to provide a reference for Ye Tianshi’s academic thoughts.Methods:We used the web v...Objective:This study analyzed the data of the medical cases in the book,“Clinical Guide Medical records”using a data mining method,to provide a reference for Ye Tianshi’s academic thoughts.Methods:We used the web version of the ancient and modern medical records cloud platform to complete distribution statistics,association rules,cluster analysis,and complex network analysis of all the medical records in the“Clinical Guide Medical records.”These methods were used to summarize the baseline data and to identify the core relationship between Chinese medicine diseases and Chinese medicine,as well as the Chinese medicine Classification.Results:A total of 2572 medical records,3136 visits,and 2879 prescriptions of 1127 traditional Chinese medicines were included in this study.The most common diseases(such as hematemesis),syndromes(such as liver–stomach disharmony),symptoms(such as rapid pulse),disease sites(such as gastric cavity),disease properties(such as Yang deficiency),treatment methods(such as activating Yang),and traditional Chinese medicines(such as Poria cocos)were identified.Furthermore,medicines with a warm,flat,cold,sweet,or bitter taste with its effects on the lungs,spleen,and heart were the most common.The observed effects of the drugs included clearing dampness,promoting diuresis,and strengthening the spleen.The association analysis showed that the associations between TCM diseases and traditional Chinese medicines that had a high confidence were“phlegm and fluid retention–Poria cocos,”“diarrhea–Poria cocos,”etc.The cluster analysis showed that traditional Chinese medicines were classified into five categories.The complex network showed the core relationship between nine high-frequency diseases and nine high-frequency traditional Chinese medicine.Conclusion:This study revealed the most important relationships between traditional Chinese medicines diseases and traditional Chinese medicines and classified the most used traditional Chinese medicines.These findings may help the coming generations of doctors to make accurate diagnoses and treat patients effectively and to improve the clinicians’efficacy in clinical diagnosis and treatment.展开更多
基金Supported by The Second Batch of Training Projects for Excellent Clinical Talents of Traditional Chinese Medicine in Guangdong Province(Yue Zhong Yi Ban Han[2017]No.267).
文摘[Objectives]Through data mining and analysis,the medication characters and ideas of ye Tianshi,a famous physician in Qing Dynasty,in the treatment of tinnitus were explored,so as to provide reference for clinical tinnitus treatment.[Methods]The medical records of Ye Tianshi's treatment of tinnitus in the Ancient and Modern Consilia Cloud Platform were retrieved and sorted,and the use frequency,properties,metabolic organ and compatibility of related Chinese herbs in the cases were analyzed through system-integrated statistical analysis,cluster analysis,association rules analysis and complex network analysis.[Results]A total of 46 medical cases were finally included,with 15 frequently used Chinese herbs,including poria with hostwood,Radix Rehmanniae Preparata,magnetitum,etc.Most of the drugs are cold and neutral in nature,sweet and bitter in taste,and metabolized in liver and heart.The results of cluster analysis show that the therapeutic drugs for tinnitus are mainly divided into four categories:strengthening spleen,nourishing yin,suppressing symptoms,and clearing heat.The results of association rules analysis show that the commonly used traditional Chinese medicine combination is composed of three herbs,poria with hostwood,Radix Ophiopogonis,and Radix et Rhizoma Glycyrrhizae,which have spleen-strengthening and stomach-tonifying effects.The results of complex network analysis show that the core prescription is based on Siwu Decoction.[Conclusions]In the treatment of tinnitus,Ye Tianshi paid attention to the three internal organs of heart,kidney and gallbladder,and made good use of lung qi-dispersing drugs to clear heat,sweet and cold drugs to tonify stomach and nourish yin,and tonic drugs to suppress symptoms.The core prescription is mainly composed of Radix Rehmanniae,Radix Rehmanniae Preparata,oyster,poria with hostwood,Fructus Forsythiae,Radix Paeoniae Alba,antelope horn,magnetitum and Radix Asparagi.The commonly used single herbs are poria with hostwood,Radix Rehmanniae Preparata and magnetitum.The combination of poria with hostwood,Radix Ophiopogonis and Radix et Rhizoma Glycyrrhizae is more common.
文摘Nancient times, is the capitalcity of Jiangsu Province atthe lower reaches of the Changjiang(Yangtze River).Its beautiful landscapehas attracted rulers and men of letterssince place for learned people in southChina and the territory of monarchs."Its ancient heritage and natural envi-ronment have now become valuableresources of local tourism.During a period of 2,600 years,Nanjing served as the capital city ofthe Eastern wu Dynasty of the ThreeKingdoms Period,the Eastern Jin Dy-nasty,the Southern Dynasties,theSouthern Tang,the Early Ming,theTaiping Heavenly Kingdom and theRepublic of China,leaving behind
文摘Epidemic diseases,known and studied in China since antiquity,are one of the main chapters of the School of Exogenous Febrile Diseases(温病学派)•Along with the legends about epidemic demons,China has developed over the centuries a medical approach based on the teachings of Huang Di Nei Jing(《黄帝内经》Internal Classic),Nan Jing(《难经》Classic of Difficulties'),and Shang Han Lun(《伤寒论》Treatise of Harmful Cold).However,it was in the 17th century,after the great break of the Song,Jin,and Yuan eras that an innovative spirit Wu Youxing(吴有性)first foresaw the existence of microorganisms as we know them now.His Wen Yi Lun(《瘟疫论》Treatise on Pestilences)foreshadows an original approach to epidemic diseases,particularly emerging infectious diseases of the 21st century:severe acute respiratory syndrome 2003-2004 and the COVID-19 pandemic are perfect examples.In this first article,which will be followed by two others,we will examine the classical and modern Chinese definitions of these dreadful plagues.
基金supported by the“National Natural Science Foundation of China:Research on the discovery of key diagnosis and treatment elements and clinical optimization decision of spleen and stomach diseases based on deep learning(NO:81873200)”the“Construction and application of an intelligent early warning system for TCM clinical drug contraindications based on rule engine(NO:ZZ150321).”。
文摘Objective:This study analyzed the data of the medical cases in the book,“Clinical Guide Medical records”using a data mining method,to provide a reference for Ye Tianshi’s academic thoughts.Methods:We used the web version of the ancient and modern medical records cloud platform to complete distribution statistics,association rules,cluster analysis,and complex network analysis of all the medical records in the“Clinical Guide Medical records.”These methods were used to summarize the baseline data and to identify the core relationship between Chinese medicine diseases and Chinese medicine,as well as the Chinese medicine Classification.Results:A total of 2572 medical records,3136 visits,and 2879 prescriptions of 1127 traditional Chinese medicines were included in this study.The most common diseases(such as hematemesis),syndromes(such as liver–stomach disharmony),symptoms(such as rapid pulse),disease sites(such as gastric cavity),disease properties(such as Yang deficiency),treatment methods(such as activating Yang),and traditional Chinese medicines(such as Poria cocos)were identified.Furthermore,medicines with a warm,flat,cold,sweet,or bitter taste with its effects on the lungs,spleen,and heart were the most common.The observed effects of the drugs included clearing dampness,promoting diuresis,and strengthening the spleen.The association analysis showed that the associations between TCM diseases and traditional Chinese medicines that had a high confidence were“phlegm and fluid retention–Poria cocos,”“diarrhea–Poria cocos,”etc.The cluster analysis showed that traditional Chinese medicines were classified into five categories.The complex network showed the core relationship between nine high-frequency diseases and nine high-frequency traditional Chinese medicine.Conclusion:This study revealed the most important relationships between traditional Chinese medicines diseases and traditional Chinese medicines and classified the most used traditional Chinese medicines.These findings may help the coming generations of doctors to make accurate diagnoses and treat patients effectively and to improve the clinicians’efficacy in clinical diagnosis and treatment.
