Efficiency and Effectiveness Method versus ε-NTU Method with Application in Finned Flat Tube Compact Heat Exchanger with Water-Ethylene Glycol as Nanofluid Base of Iron Oxide Nanoparticles

This work aims to establish comparisons between two models used for the performance of heat exchangers. The chosen system, in this case, consists of a heat exchanger used in automotive radiators flat finned tube type. Water and ethylene glycol compound as base fluid and volume fractions of iron oxide nanoparticles (Fe3O4) are used as a refrigerant. The quantities determined in this work are the nanofluid exit temperature, the air exit temperature, the absolute error between the models for heat transfer rate, and Effectiveness. The quantities that constitute parameters, independent variables, are the airflow, represented by the Reynolds number, and the iron oxide volume fraction. Ethylene Glycol 50% compound has slightly better thermal performance than pure water and reduces the reactive effect of water on the environment, increasing the average life of the equipment. The absolute relative error between the models is less than 20% and presents maximum values with the increase of the nanoparticle volume fraction and growth in the Reynolds number for the air.

Research and Innovative Analysis on the Timeliness and Effectiveness of the University Thought Political Lesson Education Practice

In this paper, we conduct research on the timeliness and effectiveness of university thought political lesson education practice. What person, how to cultivate people is developing the socialist education enterprise in our country must solve fundamental problem. College students is a national valuable human resources, are the hope of nation, the future of our motherland. To make university students grow up to be the cause of socialism with Chinese characteristics qualified builders and reliable successors, we not only need to vigorously improve their scientific and cultural quality, and actively improve their ideological and political quality. College students＇ ideological and the political education content system of the science building is refers to according to the requirements of college students＇ ideological and political education goal, to constitute elements of ideological and political education content should be reasonable configuration, make each other, permeate each other, in order to realize the content of organic integration and collaborative development.

Analysis Criteria for Defense Expenditure Performance - Economy, Efficiency, and Effectiveness

Based on the analysis of public expenditure performance,this article discusses the economy,efficiency,and effectiveness of defense expenditure performance,explains the relationship of the three,and emphasizes their unity,interaction,and priority.The defense expenditure performance evaluation system,which is a comprehensive assessment of processes and results,is put forward along with the unification of economy,efficiency,and effectiveness.This system can be used to analyze whether the allocation and use of defense funds have achieved the strategic objectives of the Department of Defense.

The Association Between Epoxide Hydrolase Genetic Variant and Effectiveness of Nicotine Replacement Therapy in a Han Chinese Population

Dear Editor, Nicotine is a psychoactive alkaloid that is thought to play a key role in addiction to commercial tobacco products [1] and cotinine is its primary metabolite [2]. Pharmacological treatment, such as nicotine replacement therapy （NRT）, is a valid solution to this problem. Tobacco smoke contains many carcinogens such as nitrosamines .

Endoscopic treatment for acute appendicitis with coexistent acute pancreatitis: Two case reports

BACKGROUND Appendectomy is the procedure of choice for the treatment of acute appendicitis.However,surgery may not be appropriate for patients with coexisting severe illness or comorbidities such as acute pancreatitis(AP).Endoscopic retrograde appendicitis treatment(ERAT)may be a novel alternative to surgery for treating such patients where existing medical therapies have failed.CASE SUMMARY We report 2 cases of moderately severe AP who developed acute uncomplicated appendicitis during their hospital stay and did not respond to traditional medical therapy.One patient had moderately severe AP due to hyperlipidemia,while the other patient had a gallstone induced by moderately severe AP.Neither patient was fit to undergo an appendectomy procedure because of the concurrent AP.Therefore,the alternative and minimally invasive ERAT was considered.After written informed consent was collected from the patients,the ERAT procedure was performed.Both patients exhibited fast postoperative recovery after ERAT with minimal surgical trauma.CONCLUSION ERAT is a safe and effective minimally invasive endoscopic procedure for acute appendicitis in patients with coexistent AP.

Biodegradable metals for bone defect repair:A systematic review and meta-analysis based on animal studies

Biodegradable metals are promising candidates for bone defect repair.With an evidence-based approach,this study investigated and analyzed the performance and degradation properties of biodegradable metals in animal models for bone defect repair to explore their potential clinical translation.Animal studies on bone defect repair with biodegradable metals in comparison with other traditional biomaterials were reviewed.Data was carefully collected after identification of population,intervention,comparison,outcome,and study design(PICOS),and following the inclusion criteria of biodegradable metals in animal studies.30 publications on pure Mg,Mg alloys,pure Zn and Zn alloys were finally included after extraction from a collected database of 2543 publications.A qualitative systematic review and a quantitative meta-analysis were performed.Given the heterogeneity in animal model,anatomical site and critical size defect(CSD),biodegradable metals exhibited mixed effects on bone defect repair and degradation in animal studies in comparison with traditional non-degradable metals,biodegradable polymers,bioceramics,and autogenous bone grafts.The results indicated that there were limitations in the experimental design of the included studies,and quality of the evidence presented by the studies was very low.To enhance clinical translation of biodegradable metals,evidence-based research with data validity is needed.Future studies should adopt standardized experimental protocols in investigating the effects of biodegradable metals on bone defect repair with animal models.

Regulatory science for hernia mesh: Current status and future perspectives

Regulatory science for medical devices aims to develop new tools,standards and approaches to assess the safety,effectiveness,quality and performance of medical devices.In the field of biomaterials,hernia mesh is a class of implants that have been successfully translated to clinical applications.With a focus on hernia mesh and its regulatory science system,this paper collected and reviewed information on hernia mesh products and biomaterials in both Chinese and American markets.The current development of regulatory science for hernia mesh,including its regulations,standards,guidance documents and classification,and the scientific evaluation of its safety and effectiveness was first reported.Then the research prospect of regulatory science for hernia mesh was discussed.New methods for the preclinical animal study and new tools for the evaluation of the safety and effectiveness of hernia mesh,such as computational modeling,big data platform and evidence-based research,were assessed.By taking the regulatory science of hernia mesh as a case study,this review provided a research basis for developing a regulatory science system of implantable medical devices,furthering the systematic evaluation of the safety and effectiveness of medical devices for better regulatory decision-making.This was the first article reviewing the regulatory science of hernia mesh and biomaterial-based implants.It also proposed and explained the concepts of evidence-based regulatory science and technical review for the first time.

Evaluation of patches for rotator cuff repair:A systematic review and meta-analysis based on animal studies

Based on the published animal studies,we systematically evaluated the outcomes of various materials for rotator cuff repair in animal models and the potentials of their clinical translation.74 animal studies were finally included,of which naturally derived biomaterials were applied the most widely(50.0%),rats were the most commonly used animal model(47.0%),and autologous tissue demonstrated the best outcomes in all animal models.The biomechanical properties of naturally derived biomaterials(maximum failure load:WMD 18.68[95%CI 7.71-29.66];P=0.001,and stiffness:WMD 1.30[95%CI 0.01-2.60];P=0.048)was statistically significant in the rabbit model.The rabbit model showed better outcomes even though the injury was severer compared with the rat model.

Analyzing the Effectiveness of Policy Implementation at the Local Level: A Case Study of Management of the 2009–2010 Drought in Yunnan Province, China

Several research efforts have focused primarily on policy implementation and improving innovative actions to address disaster risks. Discussions are ongoing on how to measure the effectiveness of policy implementation at the local level. But there is no definitive theory of effective policy implementation, and very few frameworks have been found acceptable as the basis of an analysis of the effectiveness of policy implementation, especially on droughts. Based on the 2009–2010 extreme drought in Yunnan, China, this article presents a modified framework to assess the effectiveness of policy implementation by defining policy, practice, and performance, as well as a feedback loop by which to share the lessons learned. Water conservancy projects in Luliang County and the agricultural diversity program in Longyang County in Yunnan Province were analyzed from a farmers' perspective. It was found that farmers are highly dependent on government policies and projects, and the effectiveness of policies is measured by short-term, immediate, and tangible benefits rather than long-term adaptation strategies. The results highlight the urgent need to reduce risks by developing better awareness about climate change and drought and its impacts, increased understanding of drought hazards, and implementation of appropriate measures for long-term adaptation.

A Counterbalanced Approach to Content-based Language Teaching

Content-based language teaching(CBLT)has come to be known as an effective and motivating way to develop higher levels of communicative ability than more traditional grammar-based approaches.Whereas traditional methods isolate the target language from any substantive content except for the mechanical workings of the language itself,CBLT enriches classroom discourse in a way that provides both a cognitive basis for language learning and a motivational basis for purposeful communication.CBLT,how ever,does not preclude language instruction but instead promotes its integration through a counterbalanced approach that entails a dynamic interplay betw een language and content.Drawing on classroom-based research,this paper illustrates the feasibility and effectiveness of a counterbalanced approach to CBLT whose flexibility has the potential to accommodate a range of instructional settings.