For successful animation of visitors, animators must perform very complex, demanding, and dynamic tasks. Professional performance of tasks implies the need for an animator to be a complete person. This means that he/s...For successful animation of visitors, animators must perform very complex, demanding, and dynamic tasks. Professional performance of tasks implies the need for an animator to be a complete person. This means that he/she not only must have a sound education, but also have to be specialized for certain activities. There are different types of animators so that their diversity mirrors the success of the hotel. Animators must have certain basic physical and psychological characteristics. So, despite the knowledge and experience, animators must have inherent characteristics such as talent, humour, to be friendliness, and so on. Sense of humour and ability to work with people are two important characteristics of a successful animator. Many hotels need animators who can entertain tourists and make their stay memorable resort experience, which will be a reason for return of tourists. One of the key factors for tourism success is animator. Today, the whole tourism sector is based on animation of the tourists. The purpose of this paper is to show the role of the animator in enriching the content of tourist stay. To successfully execute the animation to the tourists, animators must meet certain characteristics which will be analysed in this paper. In this research will be used methods of analysis of scientific literature on the impact of animation on enrichment of tourist stay. The research stems from the fact that animation is one of the most important animation-motivational factors for the development of tourism.展开更多
As an audiovisual medium, computer animations require superior image quality and professional soundtrack to lead audiences into their fascinating virtual world. Without sound, the impact of storytelling is reduced or ...As an audiovisual medium, computer animations require superior image quality and professional soundtrack to lead audiences into their fascinating virtual world. Without sound, the impact of storytelling is reduced or the story is even not under- standable. Despite the importance of sound, most animators are unfamiliar with sound editing software. Limited budget projects such as independent or student works have difficulty hiring sound professionals to create tailor-made soundtrack. Therefore, we need a suitable sound tool to express their individual ideas. In this paper, we propose an approach using schematic for both computer animation and sound. Our approach provides (1) physical simulation on sound through animation parameters and (2) a new channel for animators to add aesthetic values in sound through their experience of using schematics in existing animation software. We demonstrate our idea through several examples, such as Doppler shift, obstacle effect, importance, energetic, and sputtering effect.展开更多
Decades of research asserted that the oligodendroglial lineage comprises two cell types:oligodendrocyte precursor cells and oligodendrocytes.However,recent studies employing single-cell RNA sequencing techniques have ...Decades of research asserted that the oligodendroglial lineage comprises two cell types:oligodendrocyte precursor cells and oligodendrocytes.However,recent studies employing single-cell RNA sequencing techniques have uncovered novel cell states,prompting a revision of the existing terminology.Going forward,the oligodendroglial lineage should be delineated into five distinct cell states:oligodendrocyte precursor cells,committed oligodendrocyte precursor cells,newly formed oligodendrocytes,myelin-forming oligodendrocytes,and mature oligodendrocytes.This new classification system enables a deeper understanding of the oligodendroglia in both physiological and pathological contexts.Adopting this uniform terminology will facilitate comparison and integration of data across studies.This,including the consolidation of findings from various demyelinating models,is essential to better understand the pathogenesis of demyelinating diseases.Additionally,comparing injury models across species with varying regenerative capacities can provide insights that may lead to new therapeutic strategies to overcome remyelination failure.Thus,by standardizing terminology and synthesizing data from diverse studies across different animal models,we can enhance our understanding of myelin pathology in central nervous system disorders such as multiple sclerosis,Alzheimer's disease,and amyotrophic lateral sclerosis,all of which involve oligodendroglial and myelin dysfunction.展开更多
Acetyltransferases,required to transfer an acetyl group on protein are highly conserved proteins that play a crucial role in development and disease.Protein acetylation is a common post-translational modification pivo...Acetyltransferases,required to transfer an acetyl group on protein are highly conserved proteins that play a crucial role in development and disease.Protein acetylation is a common post-translational modification pivotal to basic cellular processes.Close to 80%-90%of proteins are acetylated during translation,which is an irreversible process that affects protein structure,function,life,and localization.In this review,we have discussed the various N-acetyltransferases present in humans,their function,and how they might play a role in diseases.Furthermore,we have focused on N-acetyltransferase 9 and its role in microtubule stability.We have shed light on how N-acetyltransferase 9 and acetylation of proteins can potentially play a role in neurodegenerative diseases.We have specifically discussed the N-acetyltransferase 9-acetylation independent function and regulation of c-Jun N-terminal kinase signaling and microtubule stability during development and neurodegeneration.展开更多
文摘For successful animation of visitors, animators must perform very complex, demanding, and dynamic tasks. Professional performance of tasks implies the need for an animator to be a complete person. This means that he/she not only must have a sound education, but also have to be specialized for certain activities. There are different types of animators so that their diversity mirrors the success of the hotel. Animators must have certain basic physical and psychological characteristics. So, despite the knowledge and experience, animators must have inherent characteristics such as talent, humour, to be friendliness, and so on. Sense of humour and ability to work with people are two important characteristics of a successful animator. Many hotels need animators who can entertain tourists and make their stay memorable resort experience, which will be a reason for return of tourists. One of the key factors for tourism success is animator. Today, the whole tourism sector is based on animation of the tourists. The purpose of this paper is to show the role of the animator in enriching the content of tourist stay. To successfully execute the animation to the tourists, animators must meet certain characteristics which will be analysed in this paper. In this research will be used methods of analysis of scientific literature on the impact of animation on enrichment of tourist stay. The research stems from the fact that animation is one of the most important animation-motivational factors for the development of tourism.
文摘As an audiovisual medium, computer animations require superior image quality and professional soundtrack to lead audiences into their fascinating virtual world. Without sound, the impact of storytelling is reduced or the story is even not under- standable. Despite the importance of sound, most animators are unfamiliar with sound editing software. Limited budget projects such as independent or student works have difficulty hiring sound professionals to create tailor-made soundtrack. Therefore, we need a suitable sound tool to express their individual ideas. In this paper, we propose an approach using schematic for both computer animation and sound. Our approach provides (1) physical simulation on sound through animation parameters and (2) a new channel for animators to add aesthetic values in sound through their experience of using schematics in existing animation software. We demonstrate our idea through several examples, such as Doppler shift, obstacle effect, importance, energetic, and sputtering effect.
基金supported by KU Leuven Internal Funding(C3/21/012)the Research Foundation Flanders(FWO G092222N)(to LM)。
文摘Decades of research asserted that the oligodendroglial lineage comprises two cell types:oligodendrocyte precursor cells and oligodendrocytes.However,recent studies employing single-cell RNA sequencing techniques have uncovered novel cell states,prompting a revision of the existing terminology.Going forward,the oligodendroglial lineage should be delineated into five distinct cell states:oligodendrocyte precursor cells,committed oligodendrocyte precursor cells,newly formed oligodendrocytes,myelin-forming oligodendrocytes,and mature oligodendrocytes.This new classification system enables a deeper understanding of the oligodendroglia in both physiological and pathological contexts.Adopting this uniform terminology will facilitate comparison and integration of data across studies.This,including the consolidation of findings from various demyelinating models,is essential to better understand the pathogenesis of demyelinating diseases.Additionally,comparing injury models across species with varying regenerative capacities can provide insights that may lead to new therapeutic strategies to overcome remyelination failure.Thus,by standardizing terminology and synthesizing data from diverse studies across different animal models,we can enhance our understanding of myelin pathology in central nervous system disorders such as multiple sclerosis,Alzheimer's disease,and amyotrophic lateral sclerosis,all of which involve oligodendroglial and myelin dysfunction.
基金supported by 1RO1EY032959-01 and RO1 supplement from NIH,Schuellein Chair Endowment Fund and STEM Catalyst Grant from the University of Dayton(to AS).
文摘Acetyltransferases,required to transfer an acetyl group on protein are highly conserved proteins that play a crucial role in development and disease.Protein acetylation is a common post-translational modification pivotal to basic cellular processes.Close to 80%-90%of proteins are acetylated during translation,which is an irreversible process that affects protein structure,function,life,and localization.In this review,we have discussed the various N-acetyltransferases present in humans,their function,and how they might play a role in diseases.Furthermore,we have focused on N-acetyltransferase 9 and its role in microtubule stability.We have shed light on how N-acetyltransferase 9 and acetylation of proteins can potentially play a role in neurodegenerative diseases.We have specifically discussed the N-acetyltransferase 9-acetylation independent function and regulation of c-Jun N-terminal kinase signaling and microtubule stability during development and neurodegeneration.
