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Anti-Fatigue Effect of Blended <i>Camellia oleifera Abel</i>Tea Oil and Ge-132 in Mice 被引量:5
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作者 Lisong Hu Xuezhi Fang +1 位作者 Menghao Du Jingping Zhang 《Food and Nutrition Sciences》 2015年第15期1479-1487,共9页
Nowadays, people are busier and busier for working and living, and suffer a lot of pressure on their body or mind. Therefore, people are prone to have fatigue activity and decrease their working efficiency and happine... Nowadays, people are busier and busier for working and living, and suffer a lot of pressure on their body or mind. Therefore, people are prone to have fatigue activity and decrease their working efficiency and happiness. It was reported that fatigue is a common symptom in the community, with up to half of the general population complaining of fatigue. More and more researchers devoted themselves to studying natural active ingredients in organism as the anti-fatigue drugs to release fatigue symptom. However, these natural ingredients were difficult to obtain from plants, animals and microorganisms by separating and purifying. In addition, some active substances have many side effects. In our study, we employed tea seed oil as main ingredients blended with bis-(carboxyethylgermanium) sesquioxide (Ge-132) to investigate the effects of anti-fatigue on mice by administrating mice with low dose, intermediate dose and high dose of tea seed oil complex for 0, 2 or 4 weeks. The specific tests of studying effects of anti-fatigue were body weight, weight-loaded force swimming, blood urea nitrogen, blood lactic acid and hepaticglycogen. And the results showed that appropriate level of tea seed oil complex could decrease the body weight and prolong the weight-loaded swimming time, and had an active effect on the bloodurea nitrogen, hepatic glycogen and blood lactic acid level mice, which significantly embodied the anti-fatigue activity of tea seed oil complex. 展开更多
关键词 TEA Seed OIL GE-132 anti-FATIGUE blending
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基于3,5-二溴水杨醛席夫碱镍配合物-氧化石墨烯电化学免疫传感器检测Anti-IgG含量的研究 被引量:2
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作者 赖丽燕 刘峥 +2 位作者 李巍 周昱 黄红霞 《分析科学学报》 CAS CSCD 北大核心 2014年第4期481-484,共4页
应用物理吸附法将羊抗人IgG抗原直接固定于3,5-二溴水杨醛席夫碱镍配合物-氧化石墨烯修饰的金电极表面,制备电化学免疫传感器。采用循环伏安法和交流阻抗法对传感器进行表征,结果表明该传感器适合检测Anti-IgG浓度。同时探讨了缓冲液pH... 应用物理吸附法将羊抗人IgG抗原直接固定于3,5-二溴水杨醛席夫碱镍配合物-氧化石墨烯修饰的金电极表面,制备电化学免疫传感器。采用循环伏安法和交流阻抗法对传感器进行表征,结果表明该传感器适合检测Anti-IgG浓度。同时探讨了缓冲液pH值、扫描速度、免疫反应温度、抗原与抗体配比对循环伏安峰电流的影响,结果表明在5-100mV/s扫速范围内,峰电流与扫速呈线性。孵育最优条件为25℃,h-IgG与Anti-IgG配比为1∶1。循环伏安法研究还表明Anti-IgG浓度在0.01-260μg/L范围内,线性关系良好,相关系数r^2=0.993,检出限(S/N=3)为0.006μg/L,据此建立了检测Anti-IgG浓度的新方法。 展开更多
关键词 氧化石墨烯 3 5-二溴水杨醛席夫碱镍配合物 anti—IgG 电化学免疫传感器
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信号分子IRAK1/4在antiβ-2GPI/β2GPI复合物诱导THP-1细胞表达TF中的作用探讨 被引量:1
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作者 文海平 周红 +4 位作者 许国莹 郭东琳 周芳 陈东东 解鸿翔 《中国免疫学杂志》 CAS CSCD 北大核心 2011年第4期295-299,共5页
目的:探讨IRAK1和IRAK4在antiβ-2GPI/β2GPI复合物诱导单核细胞株THP-1表达组织因子(TF)中的作用。方法:利用荧光定量PCR(Real-time PCR)、TF活性试剂盒分别检测THP-1细胞表达TF mRNA及TF活性;Western blot检测anti-β2GPI/β2GPI复合... 目的:探讨IRAK1和IRAK4在antiβ-2GPI/β2GPI复合物诱导单核细胞株THP-1表达组织因子(TF)中的作用。方法:利用荧光定量PCR(Real-time PCR)、TF活性试剂盒分别检测THP-1细胞表达TF mRNA及TF活性;Western blot检测anti-β2GPI/β2GPI复合物诱导THP-1细胞表达IRAK1、磷酸化-IRAK1(p-IRAK1)、IRAK4情况;观察IRAK1/4抑制物是否干预anti-β2GPI/β2GPI复合物诱导THP-1表达TF。结果:Antiβ-2GPI/β2GPI复合物(100μg/ml)诱导THP-1细胞表达TF显著增加(P<0.05 vs control);Antiβ-2GPI/β2GPI复合物(100μg/ml)刺激THP-1细胞表达IRAK1、p-IRAK1、IRAK4(蛋白)显著升高(P<0.05 vscontrol);IRAK1/4抑制物(50μmol/L)能够阻断antiβ-2GPI/β2GPI复合物(100μg/ml)诱导THP-1表达TF及IRAK1磷酸化的效应。结论:antiβ-2GPI/β2GPI复合物诱导THP-1细胞表达TF过程中,信号分子IRAK1/4被激活进而发挥重要作用。 展开更多
关键词 抗磷脂综合征 antiβ-2GPI/β2GPI IRAK1 IRAK4 组织因子
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三维Anti de Sitter空间中Lorentzian曲面的S_t^1×S_s^1-值光锥Gauss映射的奇点分类
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作者 于海鸥 高瑞梅 +1 位作者 孔令令 裴东河 《东北师大学报(自然科学版)》 CAS CSCD 北大核心 2010年第4期35-45,共11页
利用Arnol'd的Legendrian理论,对三维Anti de Sitter空间中Lorentzian曲面进行了研究.引入光维高度函数概念研究了三维Anti de Sitter空间Lorentzian曲面的S1t×S1s-值、光锥Gauss映射的奇点,进行了奇点分类,揭示了类光Causs-kr... 利用Arnol'd的Legendrian理论,对三维Anti de Sitter空间中Lorentzian曲面进行了研究.引入光维高度函数概念研究了三维Anti de Sitter空间Lorentzian曲面的S1t×S1s-值、光锥Gauss映射的奇点,进行了奇点分类,揭示了类光Causs-kronecker曲率之间的关系;并研究了Lorentzian曲面的一些基本几何性质. 展开更多
关键词 Lorentzian曲面 三维anti DE SITTER空间 St1×Ss1-值光锥Gauss映射 Lorentzian光维高度函数
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On the Construction of Deepening Anti - corruption Mechanism
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作者 Ding Huanxiang Xuliang 《学术界》 CSSCI 北大核心 2018年第3期260-272,共13页
It needs the foundation of system and the guarantee of organizational system for anti-corruption,but it is more necessary to build and form an effective anti-corruption mechanism,so that the anti-corruption can be rea... It needs the foundation of system and the guarantee of organizational system for anti-corruption,but it is more necessary to build and form an effective anti-corruption mechanism,so that the anti-corruption can be really put into practice. Anti-corruption mechanism refers to a organic operation system of the interaction,interconnection and constraint between the constituent elements( parts) and elements of national anti-corruption,and as a system,anti-corruption mechanism should have the characteristics of system aticness,comprehensiveness,transparency,legalization,public participation,scientific dynam ic,and internationalism. The construction of deepening anti-corruption mechanism is the need for reconstructing the ruling legitimacy of the party and the governm ent. Adhering to the principle of treating both root causes and symptoms is necessary in the construction of anti-corruption m echanism,com bating and punishing corruption is an important part of anti-corruption,and the prevention and control of corruption is the basic project of anti-corruption. Therefore,the construction of prevention and control mechanism in the anti-corruption mechanism has a more far-reaching significance. 展开更多
关键词 anti - CORRUPTION MECHANISM CONSTRUCTION CONNOTATION and definition val-ue analysis prevention and control MECHANISM
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Anti-Bacterial and Flame Retardant for Cotton Fabric by One-Bath Finishing
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作者 朱平 隋淑英 +1 位作者 王炳 孙铠 《Journal of China Textile University(English Edition)》 EI CAS 1998年第2期82-84,共3页
A research on the process of cotton fabric flame-re-tarding,anti-bacterial finishing and one-bath finish-ing of anti-bacterial and flame-retarding is discussed.The flame retardant agent was phosphorous-contained,and t... A research on the process of cotton fabric flame-re-tarding,anti-bacterial finishing and one-bath finish-ing of anti-bacterial and flame-retarding is discussed.The flame retardant agent was phosphorous-contained,and the bacteriostatic finishing agent named SFR-1 wassynthesized.The flame retardancy of the fabric finishedcan meet the DOC FF3-71 Children Sleepwear Stan-dard.Its bacterial inhibiting capacity can meet and ex-ceed the requirements of similar products 展开更多
关键词 cotton fabric flame - RETARDING FINISHING anti - BACTERIAL FINISHING one - BATH
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Testing of Anti-stripping Property of Friction Spun Core Yarn
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作者 丁辛 宋允 《Journal of China Textile University(English Edition)》 EI CAS 1998年第3期66-69,共4页
Friction spun core yarn has two components: filament core and staple fiber sheath. Under axial rubbing action, the failure mode of the core yarn is the stripping of the sheath from the core. This paper introduces a me... Friction spun core yarn has two components: filament core and staple fiber sheath. Under axial rubbing action, the failure mode of the core yarn is the stripping of the sheath from the core. This paper introduces a method to test the anti - stripping property of the core yarn. With a modified Universal Testing Machine, the stripping resistance of friction spun core yarn can be continuously measured. Some factors Influencing the measurements are discussed in detail. The testing results are compared with those from a Y731 Yarn Abrasion Tester and fur - ther confirmed by weaving practice. 展开更多
关键词 FRICTION SPUN CORE YARN anti - STRIPPING PROPERTY STRIPPING resistance testing.
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聚多巴胺涂覆LDH/PVDF改性膜的制备及性能测试
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作者 张怡萱 房平 +2 位作者 宋经华 杜明山 范恩然 《当代化工》 CAS 2024年第8期1922-1926,共5页
聚偏氟乙烯(PVDF)具有特殊的疏水性,在分离废水的过程中,污染物覆盖膜表面并堵塞膜孔会导致膜的渗透性能下降。使用浸没沉淀相转化法,通过调整水滑石(LDH)添加剂的配比和改性膜浸泡在含有盐酸多巴胺缓冲溶液中的时间,制备了LDH/PVDF改... 聚偏氟乙烯(PVDF)具有特殊的疏水性,在分离废水的过程中,污染物覆盖膜表面并堵塞膜孔会导致膜的渗透性能下降。使用浸没沉淀相转化法,通过调整水滑石(LDH)添加剂的配比和改性膜浸泡在含有盐酸多巴胺缓冲溶液中的时间,制备了LDH/PVDF改性膜及聚多巴胺(PDA)涂覆LDH/PVDF改性膜。测试了改性膜孔隙率、平均孔径、水通量、截留率、接触角、抗污染性等性能的变化。结果表明:当LDH添加量为3%时,孔隙率最大,比纯膜提升15.35%,平均孔径增加8.48 nm;膜通量最大为943.22 L·m^(-2)·h^(-1),比纯膜增加了382.95 L·m^(-2)·h^(-1),膜孔中污染物沉积减少,可逆污染占比升高,抗污染能力最强,清洗后通量恢复率为81.5%,相比纯膜M0提升了34.2%。 展开更多
关键词 多巴胺 水滑石 PVDF超滤膜 共混改性 抗污染性能
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抗高温黄变剂DM-2916N 被引量:3
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作者 吕小兰 陈建芳 +2 位作者 刘凤珍 邓东海 吴少新 《印染》 北大核心 2017年第4期47-50,共4页
将抗高温黄变剂DM-2916N应用于锦氨混纺织物的加工,讨论了水质、DM-2916N用量、轧余率等因素对抗高温黄变剂DM-2916N应用性能的影响。优化的整理工艺为:抗高温黄变剂DM-2916N 30~40 g/L,一浸一轧,轧余率(55±5)%,可有效解决白色、... 将抗高温黄变剂DM-2916N应用于锦氨混纺织物的加工,讨论了水质、DM-2916N用量、轧余率等因素对抗高温黄变剂DM-2916N应用性能的影响。优化的整理工艺为:抗高温黄变剂DM-2916N 30~40 g/L,一浸一轧,轧余率(55±5)%,可有效解决白色、浅色、敏感色锦氨纶织物在190℃以上染整加工中的高温黄变问题。 展开更多
关键词 化学整理 抗黄变 混纺织物 锦纶 氨纶
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锦/棉混纺织物防沾色优化染色工艺
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作者 岳文丽 张京彬 +3 位作者 张贻兵 刘淑云 陈华毅 陈时阳 《染整技术》 CAS 2024年第6期26-30,共5页
锦/棉混纺织物染色时,活性染料常对锦纶产生沾色,造成织物的色牢度下降及色光变化。用防沾剂对锦/棉混纺织物进行处理,以减少活性染料对锦纶的沾色情况,测试并分析了预处理温度、预处理时间、HAc用量、防沾剂用量、皂洗温度对锦纶防沾... 锦/棉混纺织物染色时,活性染料常对锦纶产生沾色,造成织物的色牢度下降及色光变化。用防沾剂对锦/棉混纺织物进行处理,以减少活性染料对锦纶的沾色情况,测试并分析了预处理温度、预处理时间、HAc用量、防沾剂用量、皂洗温度对锦纶防沾色效果的影响,同时探究了防沾剂预处理对锦纶染色的影响。当预处理温度为80℃、HAc用量为0.6 g/L、防沾剂用量为2.0 g/L、保温时间为20 min、皂洗温度为80℃时,锦纶防沾色效果最好。在优化预处理工艺下,锦纶防沾色剂不仅可有效防止活性染料对锦纶的沾色,而且对染色后织物的深度、耐汗渍色牢度、耐皂洗色牢度、耐摩擦色牢度无影响。 展开更多
关键词 防沾色剂 锦/棉混纺织物 染色 色牢度
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PBAT/TPS共混体系模压发泡制备工艺、性能及成本研究
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作者 田方伟 赵文奇 +2 位作者 黄瀚毅 赵丹 翟文涛 《材料研究与应用》 CAS 2024年第3期409-418,共10页
聚己二酸-对苯二甲酸丁二酯(PBAT)作为一种可生物降解的环保塑料,具有优异的延展性、柔韧性和成膜性能等特性,并在国家政策推动下其应用得到迅猛的发展。然而,该材料存在熔体强度低、结晶能力弱的问题,在物理发泡过程中泡孔结构易破裂坍... 聚己二酸-对苯二甲酸丁二酯(PBAT)作为一种可生物降解的环保塑料,具有优异的延展性、柔韧性和成膜性能等特性,并在国家政策推动下其应用得到迅猛的发展。然而,该材料存在熔体强度低、结晶能力弱的问题,在物理发泡过程中泡孔结构易破裂坍缩,进而导致基体收缩,因此对其发泡条件和设备要求较为苛刻。此外,PBAT原材料相对高昂的成本,也限制了其商业化发展。为此,利用便捷方法将PBAT与热塑性淀粉(TPS)熔融共混,采用超临界CO_(2)模压发泡法制备出低成本、抗收缩的PBAT/TPS泡沫。同时,研究了PBAT/TPS共混体系的热行为、流变行为,分析了不同TPS含量对PBAT/TPS泡沫的发泡行为和收缩恢复行为的影响,并针对多种典型聚合物进行成本核算比对。研究结果表明,随着TPS质量分数从10%增加至40%,TPS在PBAT/TPS共混体系中从分散相逐渐转变为连续相,TPS含量增加会导致PBAT/TPS共混体系结晶温度从40℃升高至74.5℃,平台模量增加约2个数量级,且线性黏弹区向低应变方向偏移,泡孔生长行为更容易产生。另外,TPS的加入能够提高PBAT/TPS共混体系的抗收缩能力,有利于制备成本的合理控制。当TPS的质量分数为20%时,PBAT/TPS共混体系泡沫收缩速率仅为0.017倍·min^(-1),稳定后膨胀倍率为4.7倍;相较于纯PBAT,共混体系的原料成本降低约16%。该研究为大规模商业化生产具有抗收缩的可生物降解聚酯泡沫塑料,提供了一种广泛适用的方法。 展开更多
关键词 PBAT/TPS共混体系 结晶温度 平台模量 异相成核 模压发泡 流变行为 抗收缩 低成本
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新型聚醚砜-磺化聚醚砜共混膜的性能研究 被引量:3
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作者 赵津礼 王建友 张玉忠 《水处理技术》 CAS CSCD 北大核心 2019年第6期38-42,47,共6页
以浓硫酸为聚醚砜(PES)的溶剂和磺化剂,制备磺化聚醚砜(SPES).选取磺化度(DS)为14%的SPES溶液,制备PES-SPES共混膜,考察了共混膜的脱盐效果和抗污染性能.结果表明,共混膜的基质材料中,随SPES.PES的质量比的增加,共混膜表面膜孔径增大,... 以浓硫酸为聚醚砜(PES)的溶剂和磺化剂,制备磺化聚醚砜(SPES).选取磺化度(DS)为14%的SPES溶液,制备PES-SPES共混膜,考察了共混膜的脱盐效果和抗污染性能.结果表明,共混膜的基质材料中,随SPES.PES的质量比的增加,共混膜表面膜孔径增大,断面结构由指状孔向海绵状孔转化,共混膜水通量增加,截留率降低.,当SPES的DS为14%、SPES、PES的质量比0.75时,制得共混膜水通量为253.7L/(m^2·h),对PEG6000、PEG10000和PEG20000的截留率分别为56.8%.74.5%和90.6%;共混膜在相同测试条件下对Na2SO4截留效果大于NaCL经亲水改性的PES-SPES共混膜亲水性提高,抗污染性能明显增强. 展开更多
关键词 聚醚砜 磺化聚醚砜溶液 共混膜 脱盐 抗污染
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二醋酯纤维与棉混纺针织物染整工艺探讨
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作者 解晓然 李克弯 +1 位作者 刘浩 戈剑 《天津纺织科技》 2024年第3期55-59,共5页
二醋酯纤维诞生已有近百年的历史,但因棉与二醋酯纤维混纺面料在染整过程仍然存在一些技术难点,目前二醋酯纤维与棉的混纺应用相对较少。文中主要探讨二醋酯纤维与棉混纺织物在染整过程中的技术难点,主要针对二醋酯纤维遇碱皂化以及色... 二醋酯纤维诞生已有近百年的历史,但因棉与二醋酯纤维混纺面料在染整过程仍然存在一些技术难点,目前二醋酯纤维与棉的混纺应用相对较少。文中主要探讨二醋酯纤维与棉混纺织物在染整过程中的技术难点,主要针对二醋酯纤维遇碱皂化以及色牢度偏低的技术难点,提供详细的低温前处理方案、酸性还原清洗方案、低温皂洗方案以及高效涤棉固色等解决方案,为二醋酯纤维与棉混纺织物的研究以及工业化生产提供参考。 展开更多
关键词 二醋酯纤维 混纺织物 前处理 抗皱 低温皂洗 涤棉固色
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高温掺和阀在硫磺回收装置中的应用和设计分析
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作者 刘诗梅 周位伟 +2 位作者 郭志权 范贤峰 余晓光 《阀门》 2024年第7期894-898,共5页
通过对石油和天然气行业的硫磺回收联合装置的工艺条件进行分析,介绍一种用于硫磺回收单元控制点里面的:废热、硫冷凝器、原料酸性气体和入炉空气等工艺过程中的阀门解决方案——高温掺和阀,针对阀门在此装置中的应用难点进行分析,阐述... 通过对石油和天然气行业的硫磺回收联合装置的工艺条件进行分析,介绍一种用于硫磺回收单元控制点里面的:废热、硫冷凝器、原料酸性气体和入炉空气等工艺过程中的阀门解决方案——高温掺和阀,针对阀门在此装置中的应用难点进行分析,阐述阀芯内件的结构设计、选材,保温防结晶结构、氮气吹扫气封结构以及低泄漏填料密封的结构设计方案,为石化行业内特殊工况的阀门运用提供参考方案。 展开更多
关键词 高温掺和阀 硫磺回收装置 设计分析 防结晶结构
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N,N-二甲基乙酰胺/氯化锂体系下醋酸纤维素/聚醚砜共混膜的制备与表征 被引量:2
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作者 孙中华 赵高杰 +1 位作者 陈夫山 王爱艾 《膜科学与技术》 CAS CSCD 北大核心 2017年第6期46-52,共7页
为提高纯聚醚砜(PES)膜的亲水性和抗污染能力,以N,N-二甲基乙酰胺/氯化锂(DMAc/LiCl)体系为溶剂,以聚乙烯吡咯烷酮(PVP K30)为添加剂,采用相转化法制备醋酸纤维素(CA)/聚醚砜(PES)共混膜.探讨和分析了成膜过程中的各种因素对膜纯水通量... 为提高纯聚醚砜(PES)膜的亲水性和抗污染能力,以N,N-二甲基乙酰胺/氯化锂(DMAc/LiCl)体系为溶剂,以聚乙烯吡咯烷酮(PVP K30)为添加剂,采用相转化法制备醋酸纤维素(CA)/聚醚砜(PES)共混膜.探讨和分析了成膜过程中的各种因素对膜纯水通量和BSA(牛血清蛋白)截留性能的影响.确定CA/PES共混膜的最佳铸膜条件为:聚醚砜质量分数18%,PVP K30的质量分数4%,醋酸纤维素质量分数3%,预蒸发时间为20s.对共混膜进行了SEM形貌结构、热稳定性、接触角测试、BSA抗污染性能和共混相容性分析表征.结果表明,DMAc/LiCl体系下制备的CA/PES共混膜亲水性和BSA抗污染性能高于纯PES膜,CA/PES共混体系为部分相容体系,CA/PES共混膜的高温热稳定性稍有下降. 展开更多
关键词 醋酸纤维素 抗污染性能 共混膜 亲水性
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单片机控制的空-电联合制动控制系统 被引量:1
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作者 曾晓安 周桂法 《机车电传动》 北大核心 1992年第3期18-22,43,共6页
本文较为详细地介绍了单片机控制的空气-电阻联合制动控制系统的组成、控制方式、硬件工作原理、软件结构及软件编制特点。并介绍了一种实用的实时控制中的防干扰措施。
关键词 电阻制动 控制系统 电力机车
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Morphology and Thermal Behavior of Polypropylene/Easily Hydrodegraded Polyester Blend Fibers
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作者 李梅 付中玉 +1 位作者 张大省 王庆瑞 《Journal of China Textile University(English Edition)》 EI CAS 2000年第2期50-52,共3页
Ultrafine polypropylene fibers are prepared frompolypropylene/easily hydro - degraded polyester (PP/EHDPET) blend fibers, in which file EHDPET compo-nent is degradable by treating with NaOH - H<sub>2</sub&g... Ultrafine polypropylene fibers are prepared frompolypropylene/easily hydro - degraded polyester (PP/EHDPET) blend fibers, in which file EHDPET compo-nent is degradable by treating with NaOH - H<sub>2</sub>O solu-tion. We investigated the morphology of PP/EHDPETblend fibers before and after stretching and alkalinehydrolysis. Then thermal behavior of the blend has alsobeen studied. 展开更多
关键词 POLYPROPYLENE Easily HYDRO - degraded POLYESTER blend fiber MORPHOLOGY
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Alkaline Hydrolysis of PP/EHDPET Blend Fibers
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作者 李梅 付中玉 +1 位作者 张大省 王庆瑞 《Journal of China Textile University(English Edition)》 EI CAS 1999年第3期44-47,共4页
Polypropylene superfine fibers or cell porous fibers were prepared from the bi-component blend fibers of polypropylene/easlly hydro-degraded polyester(PP/EHDPET)by alkaline hydrolysis process. EHDPET is a kind of copo... Polypropylene superfine fibers or cell porous fibers were prepared from the bi-component blend fibers of polypropylene/easlly hydro-degraded polyester(PP/EHDPET)by alkaline hydrolysis process. EHDPET is a kind of copolyester that can be rapidly hydro-degraded in the hot alkaline solution. This paper discussed the kinetics of alkaline hydrolysis of EHDPET, and the effect of catalyst, bulk ratio and the content of polypropylene grafted maleic anhydride (PP-g-MAH) on the alkaline hydrolysis process. Meanwhile, the morphological change of the outer surface of blend fibers during this process was also investigated by the technology of scanning electron microscope (SEM). 展开更多
关键词 POLYPROPYLENE ( PP) easily HYDRO - degraded POLYESTER (EHDPET) blend fibers ALKALINE HYDROLYSIS .
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<i>In Vivo</i>and <i>in Vitro</i>Evaluation of Anti Diabetic and Insulin Secretagogue Activities of <i>Capparis zeylanica</i>
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作者 Umamahesh Balekari Ciddi Veeresham 《Pharmacology & Pharmacy》 2015年第7期311-320,共10页
Since ancient times, traditional medicines have been in the usage for the treatment of Diabetes mellitus. An edible fruit from traditional medicinal plant Capparis zeylanica (CZ) was studied for its anti diabetic, ins... Since ancient times, traditional medicines have been in the usage for the treatment of Diabetes mellitus. An edible fruit from traditional medicinal plant Capparis zeylanica (CZ) was studied for its anti diabetic, insulin secretagogue activities and mechanisms involved in it. In Streptozotocin induced diabetes rats, oral administration of Capparis zeylanica methanolic extract (CZME) (200 mg/kg body weight) for 28 days showed a significant reduction in blood glucose levels by 35.53% and enhanced circulating insulin levels by 81.82% than the diabetic control rats. The insulin secretagogue activity mechanisms of the extract were evaluated by using mouse insulinoma beta cell line (MIN6-β). The extract stimulated insulin release in dependent manner of glucose concentration (3 - 16.7 mM) and extract dose (5 - 500 μg/mL). The insulin releasing effect of the extract was significantly enhanced by 3-isobutyl-1-methyl xanthine, glibenclamide, elevated extracellular calcium and K+ depolarized media. This insulin release was significantly reduced in calcium blocking conditions (by nifedipine and EGTA), in the presence of potassium channel opener (diazoxide). Hence, anti diabetic activity of CZME might be a result of its stimulatory effect on insulin release from pancreatic beta cells via KATP channel dependent and independent ways. These results indicate that CZ fruits have the potential to use in diabetes therapy. 展开更多
关键词 anti DIABETIC INSULIN Secretagogue MIN6-β Cells KATP Channel
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Exact Traveling Wave Solutions of Nano-Ionic Solitons and Nano-Ionic Current of MTs Using the exp(-φ (ξ ))-Expansion Method
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作者 Emad H. M. Zahran 《Advances in Nanoparticles》 2015年第2期25-36,共12页
In this work, the exp(-φ (ξ )) -expansion method is used for the first time to investigate the exact traveling wave solutions involving parameters of nonlinear evolution equations. When these parameters are taken to... In this work, the exp(-φ (ξ )) -expansion method is used for the first time to investigate the exact traveling wave solutions involving parameters of nonlinear evolution equations. When these parameters are taken to be special values, the solitary wave solutions are derived from the exact traveling wave solutions. The validity and reliability of the method are tested by its applications to Nano-ionic solitons wave’s propagation along microtubules in living cells and Nano-ionic currents of MTs which play an important role in biology. 展开更多
关键词 The exp(-φ )) -Expansion Method Nano-Solitons of IONIC Wave’s Propagation along Microtubules in Living Cells Nano-Ionic Currents of MTS Traveling WAVE SOLUTIONS KINK and anti KINK WAVE SOLUTIONS
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