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State of the art and practice of pavement anti-icing and de-icing techniques 被引量:5
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作者 WenBing Yu Xin Yi +1 位作者 Ming Guo Lin Chen 《Research in Cold and Arid Regions》 CSCD 2014年第1期14-21,共8页
Pavement snow and icing are worldwide problems, but effective countermeasures are just beginning to be developed in China. The two most common snow and ice removal methods are mechanical clearance and chemical melting... Pavement snow and icing are worldwide problems, but effective countermeasures are just beginning to be developed in China. The two most common snow and ice removal methods are mechanical clearance and chemical melting, and the advantages and disadvantages of each approach are discussed here, including environmental and structural damage caused by corrosive snow melting agents. New developments in chemical melting agents and mechanical equipment are discussed, and an overview of alternative thermal melting systems is presented, including the use of geothermy and non-geothermal heating systems utilizing solar energy, electricity, conductive pavement materials, and infrared/microwave applications. Strategic recommendations are made for continued enhancement of public safety in snow and ice conditions. 展开更多
关键词 PAVEMENT DE-ICING anti-icing technique freezing rain
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Vegetation Restoration Technique System and Its Ecological Functions of the Degraded Ecosystem in the Arid-Hot Valleys——Taking the Example of Typical Mode in Small Watershed of Yuanmou 被引量:2
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作者 JI Zhonghua LIAO Chengfei YANG Yanxian FANG Haidong PAN Zhixian SHA Yucang 《Wuhan University Journal of Natural Sciences》 CAS 2008年第3期257-266,共10页
This paper concluded the vegetation restoration technique system in the arid-hot valleys and studied the anti-erosion function, environmental function and biological diversity effects of vegetation restoration on the ... This paper concluded the vegetation restoration technique system in the arid-hot valleys and studied the anti-erosion function, environmental function and biological diversity effects of vegetation restoration on the ecosystem in the arid-hot valleys. The results showed that the soil erodibility decreased significantly after the vegetation restoration. The climate environment of the small watershed had a great improvement after the vegetation restoration, of which the temperature decreased, the humidity increased, the harsh environment of dry and hot in this region changed. The studies of the ecosystem biodiversity were mainly on the analysis of the relations between biodiversity and ecological function of the artificial ecological forest pattern and the natural enclosed treatment mode on the severely of degraded land. It could conclude that the natural enclosed treatment mode is helpful to the biodiversity of the ecosystem and the improvement and stability of the ecosystem, and Leucaena artificial forest restoration pattern reduced the species diversity but optimized the ecological function. Therefore, as to the severely and extremely severely degraded ecosystem in the arid-hot valleys, Leucaena pattern of gully control and natural enclosed treatment mode are the relatively optimal choices. 展开更多
关键词 vegetation restoration technique system anti-erosion function environmental function BIODIVERSITY
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The q-analogues of two-mode squeezed states constructed by virtue of the IWOP technique
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作者 孟祥国 王继锁 李洪奇 《Chinese Physics B》 SCIE EI CAS CSCD 2008年第8期2973-2978,共6页
The q-analogues of two-mode squeezed states are introduced by virtue of deformation quantization methods and the technique of integration within an ordered product (IWOP) of operators. Some new completeness relation... The q-analogues of two-mode squeezed states are introduced by virtue of deformation quantization methods and the technique of integration within an ordered product (IWOP) of operators. Some new completeness relations about these squeezed states composed of the bra and ket which are not mutually Hermitian conjugates are obtained. Furthermore, the antibunching effects of the two-mode squeezed vacuum state S's(τ) │00) are investigated. It is found that, in different ranges of the squeezed parameter τ, both modes of the state exhibit the antibunching effects and the two modes of the state are always nonclassical correlation. 展开更多
关键词 q-analogue of two-mode squeezed state IWOP technique completeness relation anti-bunching effect
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Anti-Müllerian Hormone and Its Utility in Cattle Reproduction
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作者 Garza Arredondo Aimé Jazmín Moreno Degollado Gustavo +4 位作者 Adolfo-Soto Dominguez Pérez Hernández Raymundo Alejandro Rosales S. Cedillo Zamora-Ávila Diana Castillo-Velázquez Uziel 《Open Journal of Veterinary Medicine》 CAS 2023年第1期1-11,共11页
Reproductive biotechnologies offer us greater possibilities to improve animal genetics. However, the success of these depends on different factors such as the proper selection of the donor female. For this reason, end... Reproductive biotechnologies offer us greater possibilities to improve animal genetics. However, the success of these depends on different factors such as the proper selection of the donor female. For this reason, endocrine markers have been used to evaluate the ovarian reserve, which allow a successful selection of donors. Recent research has shown, among other things, that concentrations greater than 0.130 ng/mL of anti-Mullerian hormone (also known as Muller-inhibiting substance, which is a member of the transforming growth factor beta superfamily of growth and differentiation factors) are related to donors of more than fifteen transferable embryos. Therefore, this review describes studies showing that the measurement of anti-Müllerian hormone concentrations, before superovulation programs, reduces the costs per embryo produced. 展开更多
关键词 AMH anti-Müllerian Hormone Reproductive techniques Follicular Population Granulosa Cells SUPEROVULATION
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硫酸软骨素钠的制备及抗骨关节炎活性研究进展
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作者 赵琳 云振宇 +5 位作者 吴希 张梦妍 姜雨 刘洪宇 兰韬 尹秀文 《医药导报》 CAS 北大核心 2024年第6期916-925,共10页
硫酸软骨素钠是一种硫酸化的糖胺聚糖,由D-葡萄糖醛酸和N-乙酰-D-氨基半乳糖的重复双糖单位组成。硫酸软骨素钠的工业生产是以陆地生物或海洋生物软骨组织为原料,经过特定的提取和纯化工艺制得,被认为具有抗骨关节炎及其他多种潜在的生... 硫酸软骨素钠是一种硫酸化的糖胺聚糖,由D-葡萄糖醛酸和N-乙酰-D-氨基半乳糖的重复双糖单位组成。硫酸软骨素钠的工业生产是以陆地生物或海洋生物软骨组织为原料,经过特定的提取和纯化工艺制得,被认为具有抗骨关节炎及其他多种潜在的生理活性,在保健食品、化妆品、药品等领域具有广阔的应用前景和发展空间。该文对硫酸软骨素钠的传统制备技术、微生物合成工艺的开发情况与问题,以及基于体外细胞、动物模型和临床随机对照试验的抗骨关节炎活性研究现状进行综述,分析了现阶段研究的局限性并提出相应对策,为进一步规范和开发硫酸软骨素钠提供参考。 展开更多
关键词 硫酸软骨素钠 制备技术 抗骨关节炎活性
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基于条件技术的Anti-windup设计及其在伺服系统中的应用 被引量:3
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作者 牛彬 谢清来 李钟慎 《电气自动化》 2009年第5期4-5,8,共3页
大多数执行器不可避免的会出现饱和现象,严重影响了系统的闭环性能,甚至影响系统的稳定性。为此,该文介绍了条件技术的Anti-Windup设计方法。通过引入"可行参考输入"的概念,设计了以传递函数形式表示的抗饱和补偿控制器。并... 大多数执行器不可避免的会出现饱和现象,严重影响了系统的闭环性能,甚至影响系统的稳定性。为此,该文介绍了条件技术的Anti-Windup设计方法。通过引入"可行参考输入"的概念,设计了以传递函数形式表示的抗饱和补偿控制器。并用此方法有效地解决了某型电动转台伺服系统中存在的控制器Windup问题,仿真结果表明转台伺服系统性能得到改善。 展开更多
关键词 抗积分饱和 条件技术 可行参考 伺服系统
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双层软组织缝合封闭技术在下颌骨中早期药物相关性颌骨骨坏死患者手术治疗中的应用
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作者 周颖 赵宁 +3 位作者 黄竑远 李庆祥 郭传瑸 郭玉兴 《北京大学学报(医学版)》 CAS CSCD 北大核心 2024年第1期51-56,共6页
目的:探究双层软组织缝合封闭技术在单纯应用抗骨吸收药物引起的发生在下颌骨的中早期药物相关性颌骨骨坏死(medication-related osteonecrosis of the jaw,MRONJ)患者手术治疗中的临床应用效果。方法:选择2021年10月至2022年9月于北京... 目的:探究双层软组织缝合封闭技术在单纯应用抗骨吸收药物引起的发生在下颌骨的中早期药物相关性颌骨骨坏死(medication-related osteonecrosis of the jaw,MRONJ)患者手术治疗中的临床应用效果。方法:选择2021年10月至2022年9月于北京大学口腔医院四病区经手术治疗的中早期下颌骨MRONJ患者的病历资料进行回顾性分析,收集患者术前基线临床资料,包括原发疾病、伴发疾病、用药方案(药物种类、用药时长)、MRONJ分期、临床症状、影像学表现等,所有患者在手术中行下颌骨边缘切除术去除坏死骨,运用双层软组织缝合封闭技术关闭伤口,术后定期复查随访,评价双层软组织缝合封闭技术的治疗效果及并发症,并对患者进行疼痛评分和功能状态评价。结果:研究共纳入13例患者(女12例,男1例),年龄(66.69±13.14)岁。原发疾病包括骨质疏松7例,肺癌2例,乳腺癌3例,前列腺癌1例;2例伴发糖尿病,2例伴发心血管疾病,1例伴发干燥综合征。9例患者静脉注射唑来膦酸,平均用药时间(37.7±20.0)个月,7例患者同时服用了来曲唑片等其他药物;3例患者应用地舒单抗注射液,平均用药时间(10.3±11.9)个月;5例患者服用阿仑膦酸钠片,平均用药时间(55.20±27.20)个月,2例患者不同程度地服用醋酸泼尼松片或阿卡波糖片。MRONJ 1期4例,2期9例。13例患者均采用双层软组织缝合封闭技术关闭伤口,术后平均随访11.9个月(9~17个月),13例患者皆治愈,无溢脓等并发症发生。患者术前Karnofsky功能状态评分量表(Karnofsky performance status,KPS)评分为(68.46±14.05)分,术后评分为(82.31±15.36)分,差异有统计学意义(P<0.05)。患者术前疼痛评估视觉模拟评分量表(visual analogue scale,VAS)评分为(5.77±0.73)分,术后评分为(0.38±0.51)分,差异有统计学意义(P<0.001)。结论:双层软组织缝合封闭技术在中早期单纯使用抗骨吸收类药物的下颌骨MRONJ患者中可以取得良好的临床治疗效果,可为用药情况更加复杂的MRONJ患者提供临床治疗思路。 展开更多
关键词 药物相关性颌骨骨坏死 双层软组织缝合封闭技术 边缘性颌骨切除 抗骨吸收药物 外科治疗
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随机重频激光制导雷达抗高重频干扰技术
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作者 苏兴德 郭泰 +1 位作者 詹海鸿 王涛 《激光技术》 CAS CSCD 北大核心 2024年第3期334-339,共6页
为了能有效对抗高重频干扰,在分析高重频干扰破坏激光制导雷达信号处理机理的基础上,采用了随机重频照射激光波形,并利用激光目标指示器、目标和探测器的先验距离、速度特征,提出了基于自适应交叠波门的高重频干扰信号排查和鉴别方法,... 为了能有效对抗高重频干扰,在分析高重频干扰破坏激光制导雷达信号处理机理的基础上,采用了随机重频照射激光波形,并利用激光目标指示器、目标和探测器的先验距离、速度特征,提出了基于自适应交叠波门的高重频干扰信号排查和鉴别方法,有效控制了重频干扰对目标捕获环节的影响,形成一套从波形设计到信号处理、目标捕获的端到端的抗高重频干扰解决方案,并进行了理论分析和实验验证。结果表明,在不同干扰场景下,有效捕获目标的时间均低于0.2 s,捕获时间在亚秒量级,与无干扰背景下目标典型捕获时间相当。此技术可有效对抗数十赫兹到250 kHz的固定/随机重频干扰,有利于提高制导武器对抗重频干扰的能力。 展开更多
关键词 激光技术 抗高重频干扰 交叠波门 运动特性
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山区公路桥墩桩基防磨蚀新技术探讨
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作者 陈松 马波 刘自强 《山西建筑》 2024年第11期152-154,167,共4页
跨河桥梁墩柱桩基的水流砂石冲击磨蚀问题严重危害桥梁安全。对常见的桥墩桩基防磨蚀技术进行了分析总结;在此基础上,结合山区公路桥梁工程实际给出了一种新型的防护措施——超高性能混凝土防冲刷磨蚀结构,并详细介绍了该防护结构的实... 跨河桥梁墩柱桩基的水流砂石冲击磨蚀问题严重危害桥梁安全。对常见的桥墩桩基防磨蚀技术进行了分析总结;在此基础上,结合山区公路桥梁工程实际给出了一种新型的防护措施——超高性能混凝土防冲刷磨蚀结构,并详细介绍了该防护结构的实施方法。该类防护相较于其他水工防护构造物来说混凝土用量更少,更加低碳环保。该研究成果可为类似的桥梁防磨蚀工程提供有价值的参考。 展开更多
关键词 桥墩桩基 防磨蚀技术 超高性能混凝土 防磨蚀保护结构
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市政管道渗漏的预防技术措施研究
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作者 冯英达 《工程建设与设计》 2024年第13期232-234,共3页
针对市政管道常见的渗漏问题,提出了一系列结构优化与材料创新相结合的防渗措施。这些措施有效解决了管道连接薄弱节点泄漏的问题,并实现了整体管网的防渗性能提升。对比实验和现场应用验证表明新型防渗技术不仅可以显著延长管道使用寿... 针对市政管道常见的渗漏问题,提出了一系列结构优化与材料创新相结合的防渗措施。这些措施有效解决了管道连接薄弱节点泄漏的问题,并实现了整体管网的防渗性能提升。对比实验和现场应用验证表明新型防渗技术不仅可以显著延长管道使用寿命,还能降低维护成本。 展开更多
关键词 市政管道 排水管 防渗漏 施工技术
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基于临时固结及防过转的转体桥梁施工技术优化研究
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作者 周炳 胡文柱 李亚飞 《工程建设与设计》 2024年第9期194-196,共3页
针对传统转体桥梁施工技术安全性、施工效率和质量不足的问题,以实际桥梁工程为研究对象,分析转体桥梁施工技术的难点,构建了基于砂箱及限位梁的临时锚固系统,并详细阐述基于“提前计算、过程控制、绝对制动”原则的防过转施工技术。结... 针对传统转体桥梁施工技术安全性、施工效率和质量不足的问题,以实际桥梁工程为研究对象,分析转体桥梁施工技术的难点,构建了基于砂箱及限位梁的临时锚固系统,并详细阐述基于“提前计算、过程控制、绝对制动”原则的防过转施工技术。结果表明,优化施工技术在实际操作中将累计用时误差控制在1min左右,考虑到实际施工机械的性能,符合预期的误差范围。优化施工技术在安全性、质量性和经济性方面具有明显的优势,能够提高施工效率和质量,缩短施工工期,并降低施工成本。 展开更多
关键词 临时固结 防过转 转体桥梁 施工技术
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水库堤坝工程中防渗墙施工技术研究
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作者 程文钲 《建筑技术开发》 2024年第7期48-50,共3页
防渗墙是一种用于修筑松散透水层、土石坝工程的构件。为进一步明确水库堤坝工程中防渗墙施工技术的实际应用,研究以塑性混凝土防渗墙施工技术为例,分别从施工准备阶段、混凝土试验、槽段布置与浇筑等方面,对该技术施工要点展开了分析... 防渗墙是一种用于修筑松散透水层、土石坝工程的构件。为进一步明确水库堤坝工程中防渗墙施工技术的实际应用,研究以塑性混凝土防渗墙施工技术为例,分别从施工准备阶段、混凝土试验、槽段布置与浇筑等方面,对该技术施工要点展开了分析。最后应用钻芯取样法与超声波检测技术对工程防渗墙质量进行检测。结果表明,塑形混凝土防渗墙施工技术在水库堤坝工程中的抗压强度等各项指标均达到设计标准,墙体完好无裂缝,故其符合工程设计要求。 展开更多
关键词 水库堤坝工程 防渗墙 施工技术
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公路边坡治理抗滑桩选型与施工技术研究
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作者 汪浩 《价值工程》 2024年第16期157-160,共4页
在公路边坡治理中,抗滑桩是一项关键技术,对保障道路安全和维护交通流畅起着至关重要的作用。面对复杂多变的地质条件和环境因素,选择合适的抗滑桩类型及其施工技术成为了一个挑战。本文以G344东灵线栾川秋扒至三川皮皮岭段工程项目为背... 在公路边坡治理中,抗滑桩是一项关键技术,对保障道路安全和维护交通流畅起着至关重要的作用。面对复杂多变的地质条件和环境因素,选择合适的抗滑桩类型及其施工技术成为了一个挑战。本文以G344东灵线栾川秋扒至三川皮皮岭段工程项目为背景,从工程特点、抗弯性能、经济性、施工效率四个方面进行抗滑桩比选,综合所有因素考虑,最终采用圆形抗滑桩边坡治理施工方案。针对圆形抗滑桩施工,提出了施工技术要点,优化了施工工艺,以期为公路边坡治理提供指导和借鉴。 展开更多
关键词 边坡治理 抗滑桩选型 施工技术
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基于Anti-Windup的感应电机高速区最大转矩提升策略 被引量:5
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作者 董震 于泳 +2 位作者 王勃 张旭 徐殿国 《中国电机工程学报》 EI CSCD 北大核心 2018年第3期899-908,共10页
充分利用直流母线电压是提升感应电机输出转矩的有效途径。传统电压闭环方法在进行电压极限圆拓宽时,必然会出现windup问题,这将导致系统动态响应变差并影响转矩输出。该文提出一种基于Anti-Windup的感应电机高速弱磁最大转矩提升策略,... 充分利用直流母线电压是提升感应电机输出转矩的有效途径。传统电压闭环方法在进行电压极限圆拓宽时,必然会出现windup问题,这将导致系统动态响应变差并影响转矩输出。该文提出一种基于Anti-Windup的感应电机高速弱磁最大转矩提升策略,通过空间矢量脉宽调制算法过调制前后矢量合成的作用时间进行闭环弱磁,运用梯度下降法校正励磁电流给定。在提高直流母线电压利用率的同时,缓解了电流调节器的失控问题。仿真和对比实验结果表明,该文方法实现了最大转矩的提升,加快了电机升速过程。 展开更多
关键词 感应电机 转矩提升 电压拓宽 windup现象 高速弱磁控制
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Distance-Measuring Technology Using LD for Auto Anti-Collision 被引量:2
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作者 ZhangXin-bao LuHong LiZhu 《Wuhan University Journal of Natural Sciences》 EI CAS 2004年第1期83-88,共6页
Auto anti-collision technology is one of the main research subjects of automobiles’ safety technology. Aiming at the key technology of Auto anti-collision, measuring the distance from obstacles, based on the theory o... Auto anti-collision technology is one of the main research subjects of automobiles’ safety technology. Aiming at the key technology of Auto anti-collision, measuring the distance from obstacles, based on the theory of phase laser distance ranging, Laser Diode (LD) distance-measuring system for auto anti-collision has been developed to solve the problem of on-line measuring distance technology in middle to long distance utilizing the good characteristics of LD when modulating its optical intensity and adopting typical kinds of filter techniques in this paper. By theoretical analysis, adopting typical kinds of filter techniques can reduce the interference of strong light, so distance-measuring range can be 0.5–100 m in daytime or 1–200 m at night. And more, from theoretical analysis and experiment result, it can guarantee the high measuring resolution which can be less than 24.5 mm, utilizing the method of two Laser Diode optical intensity modulating wavelength and complimenting precise calibration and revision. The idea of LD distance-measuring technology is novel and feasible and this technology can be applied in Auto anti-collision. Key words laser diode - phase laser distance ranging - filter techniques - auto anti-collision CLC number TH 161 Foundation item: Supported by the National Natural Science Foundation of China (59675080, 59805006) and Wuhan Chenguang Foundation (20025001001)Biography: Zhang Xin-bao (1965-), male, Associate professor, research direction: precise mechanism and instrument. 展开更多
关键词 laser diode phase laser distance ranging filter techniques auto anti-collision
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APPLICATION OF TREFFTZ BEM TO ANTI-PLANE PIEZOELECTRIC PROBLEM 被引量:1
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作者 Wang Juan Cui Yuhong +1 位作者 Qin Qinghua Jia Jiangying 《Acta Mechanica Solida Sinica》 SCIE EI 2006年第4期352-364,共13页
Anti-plane electroelastic problems are studied by the Trefftz boundary element method (BEM) in this paper. The Trefftz BEM is based on a weighted residual formulation and indirect boundary approach. In particular th... Anti-plane electroelastic problems are studied by the Trefftz boundary element method (BEM) in this paper. The Trefftz BEM is based on a weighted residual formulation and indirect boundary approach. In particular the point-collocation and Galerkin techniques, in which the basic unknowns are the retained expansion coefficients in the system of complete equations, are considered. Furthermore, special Trefftz functions and auxiliary functions which satisfy exactly the specified boundary conditions along the slit boundaries are also used to derive a special purpose element with local defects. The path-independent integral is evaluated at the tip of a crack to determine the energy release rate for a mode Ⅲ fracture problem. In final, the accuracy and efficiency of the Trefftz boundary element method are illustrated by an example and the comparison is made with other methods. 展开更多
关键词 Trefftz boundary element point-collocation technique Galerkin technique special trial function anti-plane fracture piezoelectric medium
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ANTI-PLANE CRACK MOVING ALONG THE INTERFACE OF DISSIMILAR PIEZOELECTRIC MATERIALS
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作者 Chen, ZT Yu, SW 《Acta Mechanica Solida Sinica》 SCIE EI 1999年第1期31-35,共5页
The problem of an anti-plane Griffith crack moving along the interface of dissimilar piezoelectric materials is solved by using the integral transform technique. It is shown from the result that the intensity factors ... The problem of an anti-plane Griffith crack moving along the interface of dissimilar piezoelectric materials is solved by using the integral transform technique. It is shown from the result that the intensity factors of anti-plane stress and electric displacement around the crack tip are dependent on the speed of the Griffith crack as well as the material coefficients. When the two piezoelectric materials are identical, the present result will be reduced to the result far the problem of an anti-plane moving Griffith crack in homogeneous piezoelectric materials. 展开更多
关键词 INTERFACE Griffith crack piezoelectric material anti-plane fracture integral transform technique
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Evaluation of extraction protocols for anti-diabetic phytochemical substances from medicinal plants
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作者 Stanley Irobekhian Reuben Okoduwa Ismaila A Umar +2 位作者 Dorcas B James Hajara M Inuwa James D Habila 《World Journal of Diabetes》 SCIE CAS 2016年第20期605-614,共10页
AIM To examine the efficacy of three extraction techniques: Soxhlet-extraction(SE), cold-maceration(CM) and microwave-assisted-extraction(MAE) using 80% methanol as solvent. METHODS The study was performed on each of ... AIM To examine the efficacy of three extraction techniques: Soxhlet-extraction(SE), cold-maceration(CM) and microwave-assisted-extraction(MAE) using 80% methanol as solvent. METHODS The study was performed on each of 50 g of Vernonia amygdalina(VA) and Occimum gratissimum(OG) leaves respectively. The percentage yield, duration of extraction, volume of solvent used, qualitative and quantitative phytoconstituents present was compared. The biological activities(hypoglycemic effect) were investigated using albino wistar rat model of diabetes mellitus(n = 36) with a combined dose(1:1) of the two plants leaf extracts(250 mg/kg b.w.) from the three methods. Theextracts were administered orally, once daily for 21 d.RESULTS In this report, the percentage VA extract yield from MAE was highest(20.9% ± 1.05%) within 39 min using 250 m L of solvent, when compared to the CM(14.35% ± 0.28%) within 4320 min using 900 m L of solvent and SE(15.75% ± 0.71%) within 265 min using 500 m L of solvent. The percentage differences in OG extract yield between: MAE vs SE was 41.05%; MAE vs CM was 46.81% and SE vs CM was 9.77%. The qualitative chemical analysis of the two plants showed no difference in the various phytoconstituents tested, but differs quantitatively in the amount of the individual phytoconstituents, as MAE had significantly high yield(P > 0.05) on phenolics, saponins and tannins. SE technique gave significantly high yield(P > 0.05) on alkaloid, while CM gave significant high yield on flavonoids. The extracts from CM exhibited a significantly(P > 0.05) better hypoglycemic activity within the first 14-d of treatment(43.3% ± 3.62%) when compared to MAE(36.5% ± 0.08%) and SE methods(33.3% ± 1.60%). However, the percentage hypoglycemic activity, 21 d post-treatment with 250 mg/kg b.w. extract from MAE was 72.6% ± 1.03% and it was more comparable to 10 mg/kg b.w. glibenclamide treated group(75.0% ± 0.73%), unlike the SE(69.5% ± 0.71%) and CM(69.1% ± 1.03%). CONCLUSION CM technique produces extract with better hypoglycemic activity, whereas; MAE is a better option for high yield of phytoconstituents using less solvent within a short time. 展开更多
关键词 EXTRACTION techniques Microwave-assistedextraction MACERATION PHYTOCONSTITUENTS Medicinal plants SOXHLET anti-diabetes
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经皮骨钩股骨近端防旋髓内钉内固定术治疗股骨粗隆间骨折的疗效及安全性 被引量:3
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作者 马超 宋矿朋 刘向林 《局解手术学杂志》 2023年第7期625-628,共4页
目的探究经皮骨钩股骨近端防旋髓内钉(PFNA)内固定术治疗股骨粗隆间骨折的疗效及安全性。方法前瞻性选取2020年6月至2022年6月在我院进行手术治疗的212例股骨粗隆间骨折患者作为研究对象,采用随机数字表法分为观察组与对照组,各106例。... 目的探究经皮骨钩股骨近端防旋髓内钉(PFNA)内固定术治疗股骨粗隆间骨折的疗效及安全性。方法前瞻性选取2020年6月至2022年6月在我院进行手术治疗的212例股骨粗隆间骨折患者作为研究对象,采用随机数字表法分为观察组与对照组,各106例。对照组患者采取PFNA内固定术治疗,观察组在对照组基础上使用经皮骨钩技术复位。对比2组患者手术与康复相关指标;比较2组术前及术后1、2个月髋关节功能Harris评分、Barthel指数评分差异;观察2组并发症发生情况。结果观察组手术时间明显长于对照组(P<0.05),术后住院时间、开始负重时间及骨折愈合时间均短于对照组(P<0.05)。重复测量方差结果表明,2组患者不同时点Harris评分以时间因素为源、以组别为源的主体间效应及以时间与组别交互为源的主体内效应间比较差异具有统计学意义(P<0.05);观察组术后1、2个月Harris评分均显著高于对照组(P<0.05)。重复测量方差结果表明,2组患者不同时点Barthel指数评分以时间因素为源、以组别为源的主体间效应及以时间与组别交互为源的主体内效应间比较差异具有统计学意义(P<0.05);观察组术后1、2个月Barthel指数评分均显著高于对照组(P<0.05)。观察组并发症总发生率显著低于对照组(P<0.05)。结论经皮骨钩PFNA内固定术治疗股骨粗隆间骨折的效果显著,能够有效促进患者康复,改善髋关节功能及功能障碍,减少并发症的发生。 展开更多
关键词 经皮骨钩技术 股骨近端防旋髓内钉 内固定 股骨粗隆间骨折 临床疗效 并发症
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用p[Tj(a-)]外周血淋巴细胞建立抗-PP1P^(k)杂交瘤细胞株
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作者 郭忠慧 朱自严 +2 位作者 向东 赵俸涌 杨颖 《中国输血杂志》 CAS 2023年第4期294-298,共5页
目的建立分泌抗-PP1P^(k)(又称抗-Tj^(a))的淋巴母细胞样细胞系(lymphoblastoid cell line,LCL)和单克隆杂交瘤细胞株。方法无菌条件下常规方法制备p[Tj(a-)]血型献血者外周血单个核细胞(Peripheral blood mononuclear cells,PBMC),用E... 目的建立分泌抗-PP1P^(k)(又称抗-Tj^(a))的淋巴母细胞样细胞系(lymphoblastoid cell line,LCL)和单克隆杂交瘤细胞株。方法无菌条件下常规方法制备p[Tj(a-)]血型献血者外周血单个核细胞(Peripheral blood mononuclear cells,PBMC),用EB病毒(Epstein-Barr virus,EBV)转化单个核细胞中的B淋巴细胞,使其增殖形成B淋巴母细胞样细胞克隆。用菠萝酶处理的正常AB型和O型红细胞以及p[Tj(a-)]红细胞筛选培养上清,通过显微吸引分离技术获得分泌特异性抗-PP1P^(k)的LCL,与SHM-D33骨髓瘤细胞进行融合。异源杂交瘤细胞经次黄嘌呤(H)-氨基蝶呤(A)-胸腺嘧啶(T)-脱氧胞嘧啶核苷(D)-毒毛旋花苷(O)即HOTD培养基选择性培养、抗体筛选以及有限稀释亚克隆,建立分泌特异性抗体的单克隆杂交瘤细胞株。结果从O型p[Tj(a-)]献血者外周血B淋巴细胞EBV转化细胞培养上清中,初筛得到与正常红细胞全部凝集,与p[Tj(a-)]红细胞不凝集的单个淋巴母细胞样克隆5E1-E5,初步鉴定培养上清具有抗-PP1P^(k)特异性。随后利用杂交瘤技术,将5E1-E5细胞与SHM-D33骨髓瘤细胞进行融合,建立了持续稳定分泌IgM抗-PP1P^(k)的单克隆杂交瘤细胞株。结论本研究通过EBV转化和杂交瘤技术建立了分泌抗-PP1P^(k)的人单克隆细胞株,这项工作使大规模筛选稀有p[Tj(a-)]血型成为可能,对我国稀有血型库的建设具有重要意义。 展开更多
关键词 p[Tj(a-)] 抗-PP1P^(k) 抗-Tj^(a) 杂交瘤技术 人单克隆抗体
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