When the radio frequency identification(RFID)system inventories multiple tags,the recognition rate will be seriously affected due to collisions.Based on the existing dynamic frame slotted Aloha(DFSA)algorithm,a sub-fr...When the radio frequency identification(RFID)system inventories multiple tags,the recognition rate will be seriously affected due to collisions.Based on the existing dynamic frame slotted Aloha(DFSA)algorithm,a sub-frame observation and cyclic redundancy check(CRC)grouping combined dynamic framed slotted Aloha(SUBF-CGDFSA)algorithm is proposed.The algorithm combines the precise estimation method of the quantity of large-scale tags,the large-scale tags grouping mechanism based on CRC pseudo-randomcharacteristics,and the Aloha anti-collision optimization mechanism based on sub-frame observation.By grouping tags and sequentially identifying themwithin subframes,it accurately estimates the number of remaining tags and optimizes frame length accordingly to improve efficiency in large-scale RFID systems.Simulation outcomes demonstrate that this proposed algorithmcan effectively break through the system throughput bottleneck of 36.8%,which is up to 30%higher than the existing DFSA standard scheme,and has more significant advantages,which is suitable for application in largescale RFID tags scenarios.展开更多
Over the last two decades,the dogma that cell fate is immutable has been increasingly challenged,with important implications for regenerative medicine.The brea kth rough discovery that induced pluripotent stem cells c...Over the last two decades,the dogma that cell fate is immutable has been increasingly challenged,with important implications for regenerative medicine.The brea kth rough discovery that induced pluripotent stem cells could be generated from adult mouse fibroblasts is powerful proof that cell fate can be changed.An exciting extension of the discovery of cell fate impermanence is the direct cellular reprogram ming hypothesis-that terminally differentiated cells can be reprogrammed into other adult cell fates without first passing through a stem cell state.展开更多
The brain's extracellular matrix(ECM),which is comprised of protein and glycosaminoglycan(GAG)scaffolds,constitutes 20%-40% of the human brain and is considered one of the largest influencers on brain cell functio...The brain's extracellular matrix(ECM),which is comprised of protein and glycosaminoglycan(GAG)scaffolds,constitutes 20%-40% of the human brain and is considered one of the largest influencers on brain cell functioning(Soles et al.,2023).Synthesized by neural and glial cells,the brain's ECM regulates a myriad of homeostatic cellular processes,including neuronal plasticity and firing(Miyata et al.,2012),cation buffering(Moraws ki et al.,2015),and glia-neuron interactions(Anderson et al.,2016).Considering the diversity of functions,dynamic remodeling of the brain's ECM indicates that this understudied medium is an active participant in both normal physiology and neurological diseases.展开更多
Objective:To explore the perspectives of high-risk pregnant women regarding the home care program for high-risk pregnancies.Methods:This qualitative study was conducted in a university hospital and 5 comprehensive hea...Objective:To explore the perspectives of high-risk pregnant women regarding the home care program for high-risk pregnancies.Methods:This qualitative study was conducted in a university hospital and 5 comprehensive health centers in Ahvaz,Iran,from February 2023 to July 2023.The sampling method used was purposive sampling considering the maximum possible diversity,which continued until data saturation.11 in-depth and semistructured interviews were conducted with high-risk pregnant women.Data were simultaneously analysed using Graneheim and Lundman content analysis by MAXQDA version 20 software.Results:Data analysis extracted 3 themes,12 categories,and 26 subcategories.The themes and categories were“high-risk pregnancy and related issues(pursuing treatment and paying attention to the high-risk situation by pregnant women,psychological aspect of high-risk pregnancy on pregnant women and caregivers,emotional and physical aspects of high-risk pregnancy,the consequences of high-risk pregnancy on the people around them and empowerment of high-risk pregnant women)”,“support dimension(family and community support for high-risk pregnant women)”,and“framework of program(acculturalization,means and equipment,security,manpower and the necessary arrangements for the home care)”.Conclusions:High-risk pregnancy affects various aspects of the lives of high-risk pregnant women and their families.Creating the necessary conditions for providing care at home plays a vital role in supporting high-risk pregnant women and removing related obstacles to receiving prenatal care in person.It will be especially beneficial for high-risk pregnant women in low-income areas.展开更多
This study focuses on"Longxuhuang",a fresh agricultural product from Longtian Town in Longmen County.By establishing the objectives of brand promotion and analyzing the appropriate promotional channels,we ai...This study focuses on"Longxuhuang",a fresh agricultural product from Longtian Town in Longmen County.By establishing the objectives of brand promotion and analyzing the appropriate promotional channels,we aim to effectively position the brand,cultivate a promotional atmosphere,identify suitable channels for promotion,anticipate potential risks,and propose corresponding countermeasures.Additionally,we assess the effectiveness of the promotional strategies employed.The findings of this research will contribute to the brand promotion of enterprises and offer insights for the brand promotion of agricultural products in other regions.展开更多
This editorial discusses Christodoulidis et al's article,which appeared in the most recent edition.The clinical trials have demonstrated the programmed cell death receptor 1(PD-1)inhibitor Pembrolizumab involved c...This editorial discusses Christodoulidis et al's article,which appeared in the most recent edition.The clinical trials have demonstrated the programmed cell death receptor 1(PD-1)inhibitor Pembrolizumab involved combination therapy can improve the efficacy of advanced gastric cancer(AGC).Pembrolizumab combined with chemotherapy can enhance its sensitivity,and further eliminate tumor cells that develop resistance to chemotherapy.The combination of Pembrolizumab and Trastuzumab targeting human epidermal growth factor receptor 2 showed improved prognosis.The overall toxic effects of Pembrolizumab are significantly lower than traditional chemotherapy,and the safety is controllable.PD-1 inhibitor Pembrolizumab sheds a light on the treatment of AGC and brings new hope to the clinical practice.展开更多
BACKGROUND Immune checkpoint inhibitors(ICIs)are a new class of antitumor agents.They enhance antitumor effects by blocking inhibitory receptors and related ligands expressed on T cells.ICIs also modulate regular immu...BACKGROUND Immune checkpoint inhibitors(ICIs)are a new class of antitumor agents.They enhance antitumor effects by blocking inhibitory receptors and related ligands expressed on T cells.ICIs also modulate regular immune cell activity,affecting the immune system and causing immune-related adverse events.The renal system is sometimes affected by these adverse events.Currently,the literature on ICIs-related glomerular injuries is scarce.CASE SUMMARY We present a patient who developed granulomatosis with polyangiitis(GPA)3 weeks after treatment with the anti-programmed cell death-1 inhibitor,tislel-izumab.The patient experienced proteinuria,hematuria,and acute kidney injury without pulmonary hemorrhage and tested positive for anti-neutrophil cyto-plasmic antibody(ANCA)-cytoplasmic type.Renal biopsy confirmed ANCA-associated vasculitis,and GPA was finally diagnosed.The patient received pulse treatment with glucocorticoids and cyclophosphamide,and renal function improved.After self-discontinuation of the drug,the disease recurred,and the original treatment regimen was continued.However,the patient’s renal function continued to deteriorate.CONCLUSION Glucocorticoids plus cyclophosphamide are effective for treating GPA induced by tislelizumab.However,follow-up and patient education are needed.展开更多
A novel anti-collision algorithm in RFID wireless network is proposed.As it is put forward on the basis of collision tree(CT)and improved collision tree(lCT) anti-collision protocols,we call it adaptive collision tree...A novel anti-collision algorithm in RFID wireless network is proposed.As it is put forward on the basis of collision tree(CT)and improved collision tree(lCT) anti-collision protocols,we call it adaptive collision tree protocol(ACT).The main novelty of this paper is that the AD strategy is introduced and used in ACT to decrease collisions and improve the tag system throughput.AD strategy means that query strings will divide into two or four branches adaptively according to the label quantity.This scheme can decrease both depth of query and collision timeslots,and avoid producing too much idle timeslots at the same time.Both theoretical analysis and simulation results indicate that the novel proposed anticollision protocol ACT outperforms the previous CT and ICT protocols in term of time complexity,system throughput,and communication complexity.展开更多
Collision and security issues are considered as barriers to RFID applications.In this paper,a parallelizable anti-collision based on chaotic sequence combined dynamic frame slotted aloha to build a high-efficiency RFI...Collision and security issues are considered as barriers to RFID applications.In this paper,a parallelizable anti-collision based on chaotic sequence combined dynamic frame slotted aloha to build a high-efficiency RFID system is proposed.In the tags parallelizable identification,we design a Discrete Markov process to analyze the success identification rate.Then a mutual authentication security protocol merging chaotic anti-collision is presented.The theoretical analysis and simulation results show that the proposed identification scheme has less than 45.1%of the identification time slots compared with the OVSF-system when the length of the chaos sequence is 31.The success identification rate of the proposed chaotic anti-collision can achieve 63%when the number of the tag is100.We test the energy consumption of the presented authentication protocol,which can simultaneously solve the anti-collision and security of the UHF RFID system.展开更多
A priori knowledge of the number of tags is crucial for anti-collision protocols in slotted UHF RFID systems.The number of tags is used to decide optimal frame length in dynamic frame slotted ALOHA(DFSA)and to adjust ...A priori knowledge of the number of tags is crucial for anti-collision protocols in slotted UHF RFID systems.The number of tags is used to decide optimal frame length in dynamic frame slotted ALOHA(DFSA)and to adjust access probability in random access protocols.Conventional researches estimate the number of tags in MAC layer based on statistics of empty slots,collided slots and successful slots.Usually,a collision detection algorithm is employed to determine types of time slots.Only three types are distinguished because of lack of ability to detect the number of tags in single time slot.In this paper,a physical layer algorithm is proposed to detect the number of tags in a collided slot.Mean shift algorithm is utilized,and some properties of backscatter signals are investigated.Simulation results verify the effectiveness of the proposed solution in terms of low estimation error with a high SNR range,outperforming the existing MAC layer approaches.展开更多
Recently,object identification with radio frequency identification(RFID)technology is becoming increasingly popular.Identification time is a key performance metric to evaluate the RFID system.The present paper analyze...Recently,object identification with radio frequency identification(RFID)technology is becoming increasingly popular.Identification time is a key performance metric to evaluate the RFID system.The present paper analyzes the deficiencies of the state-of-the-arts algorithms and proposes a novel sub-frame-based algorithm with adaptive frame breaking policy to lower the tag identification time for EPC global C1 Gen2 UHF RFID standard.Through the observation of slot statistics in a sub-frame,the reader estimates the tag quantity and efficiently calculates an optimal frame size to fit the unread tags.Only when the expected average identification time in the calculated frame size is less than that in the previous frame size,the reader starts the new frame.Moreover,the estimation of the proposed algorithm is implemented by the look-up tables,which allows dramatically reduction in the computational complexity.Simulation results show noticeable throughput and time efficiency improvements of the proposed solution over the existing approaches.展开更多
Radio frequency identification(RFID)has been widespread used in massive items tagged domains.However,tag collision increases both time and energy consumption of RFID network.Tag collision can seriously affect the succ...Radio frequency identification(RFID)has been widespread used in massive items tagged domains.However,tag collision increases both time and energy consumption of RFID network.Tag collision can seriously affect the success of tag identification.An efficient anti-collision protocol is very crucially in RFID system.In this paper,an improved binary search anti-collision protocol namely BRTP is proposed to cope with the tag collision concern,which introduces a Bi-response mechanism.In Bi-response mechanism,two groups of tags allowed to reply to the reader in the same slot.According to Bi-response mechanism,the BRTP strengthens the tag identification of RFID network by reducing the total number of queries and exchanged messages between the reader and tags.Both theoretical analysis and numerical results verify the effectiveness of the proposed BRTP in various performance metrics including the number of total slots,system efficiency,communication complexity and total identification time.The BRTP is suitable to be applied in passive RFID systems.展开更多
Due to more tag-collisions result in failed transmissions,tag anti-collision is a very vital issue in the radio frequency identification(RFID) system.However,so far decreases in communication time and increases in thr...Due to more tag-collisions result in failed transmissions,tag anti-collision is a very vital issue in the radio frequency identification(RFID) system.However,so far decreases in communication time and increases in throughput are very limited.In order to solve these problems,this paper presents a novel tag anti-collision scheme,namely adaptive hybrid search tree(AHST),by combining two algorithms of the adaptive binary-tree disassembly(ABD) and the combination query tree(CQT),in which ABD has superior tag identification velocity and CQT has optimum performance in system throughput and search timeslots.From the theoretical analysis and numerical simulations,the proposed algorithm can colligate the advantages of above algorithms,improve the system throughput and reduce the searching timeslots dramatically.展开更多
In this paper, we develop a novel mathematical model to estimate the probability distribution function of the number of tags discovered after a certain number of interrogation rounds. In addition, the pdfs of the numb...In this paper, we develop a novel mathematical model to estimate the probability distribution function of the number of tags discovered after a certain number of interrogation rounds. In addition, the pdfs of the number of rounds needed to discover all the tags are also calculated. The estimation of such pdfs will be helpful in estimating the number of interrogation rounds and the optimal parameter configuration of the RFID system which in turn will be helpful in estimating the time needed to discover all tags. Our results show that the proposed model accurately predicts the tags detection probability. We then use the proposed model to optimally configure the reader parameters (i.e. the frame size and the number of interrogation rounds).展开更多
Auto anti-collision technology is one of the main research subjects of automobiles’ safety technology. Aiming at the key technology of Auto anti-collision, measuring the distance from obstacles, based on the theory o...Auto anti-collision technology is one of the main research subjects of automobiles’ safety technology. Aiming at the key technology of Auto anti-collision, measuring the distance from obstacles, based on the theory of phase laser distance ranging, Laser Diode (LD) distance-measuring system for auto anti-collision has been developed to solve the problem of on-line measuring distance technology in middle to long distance utilizing the good characteristics of LD when modulating its optical intensity and adopting typical kinds of filter techniques in this paper. By theoretical analysis, adopting typical kinds of filter techniques can reduce the interference of strong light, so distance-measuring range can be 0.5–100 m in daytime or 1–200 m at night. And more, from theoretical analysis and experiment result, it can guarantee the high measuring resolution which can be less than 24.5 mm, utilizing the method of two Laser Diode optical intensity modulating wavelength and complimenting precise calibration and revision. The idea of LD distance-measuring technology is novel and feasible and this technology can be applied in Auto anti-collision. Key words laser diode - phase laser distance ranging - filter techniques - auto anti-collision CLC number TH 161 Foundation item: Supported by the National Natural Science Foundation of China (59675080, 59805006) and Wuhan Chenguang Foundation (20025001001)Biography: Zhang Xin-bao (1965-), male, Associate professor, research direction: precise mechanism and instrument.展开更多
Multi-tag collision imposes a vital detrimental effect on reading performanceof an RFID system. In order to ameliorate such collision problem and to improve thereading performance, this paper proposes an efficient tag...Multi-tag collision imposes a vital detrimental effect on reading performanceof an RFID system. In order to ameliorate such collision problem and to improve thereading performance, this paper proposes an efficient tag identification algorithm termedas the Enhanced Adaptive Tree Slotted Aloha (EATSA). The key novelty of EATSA is toidentify the tags using grouping strategy. Specifically, the whole tag set is divided intogroups by a frame of size F. In cases multiple tags fall into a group, the tags of the groupare recognized by the improved binary splitting (IBS) method whereas the rest tags arewaiting in the pipeline. In addition, an early observation mechanism is introduced toupdate the frame size to an optimum value fitting the number of tags. Theoretical analysisand simulation results show that the system throughput of our proposed algorithm canreach as much as 0.46, outperforming the prior Aloha-based protocols.展开更多
In this paper,a dynamic multi-ary query tree(DMQT)anti-collision protocol for Radio Frequency Identification(RFID)systems is proposed for large scale passive RFID tag identification.The proposed DMQT protocol is based...In this paper,a dynamic multi-ary query tree(DMQT)anti-collision protocol for Radio Frequency Identification(RFID)systems is proposed for large scale passive RFID tag identification.The proposed DMQT protocol is based on an iterative process between the reader and tags which identifies the position of collision bits through map commands and dynamically encodes them to optimize slots allocation through query commands.In this way,the DMQT completely eliminates empty slots and greatly reduces collision slots,which in turn reduces the identification time and energy costs.In addition and differently to other known protocols,the DMQT does not need to estimate the number of tags,reducing the protocol implementation complexity and eliminating the uncertainty caused by the estimation algorithm.A numerical analysis shows that DMQT has better performance than other algorithms for a number of tags larger than 300.Meanwhile,when the number of tags is 2000 and the tag identity(ID)length is 128 bits,the total identification time is 2.58 s and the average energy cost for a tag identification is 1.2 mJ,which are 16.9%and 10.4%less than those of state-of-the-art algorithms,respectively.In addition,a DMQT extension based on ACK command has also been presented to deal with capture effect and avoid missing identification.展开更多
In RFID(Radio Frequency IDentification)system,when multiple tags are in the operating range of one reader and send their information to the reader simultaneously,the signals of these tags are superimposed in the air,w...In RFID(Radio Frequency IDentification)system,when multiple tags are in the operating range of one reader and send their information to the reader simultaneously,the signals of these tags are superimposed in the air,which results in a collision and leads to the degrading of tags identifying efficiency.To improve the multiple tags’identifying efficiency due to collision,a physical layer network coding based binary search tree algorithm(PNBA)is proposed in this paper.PNBA pushes the conflicting signal information of multiple tags into a stack,which is discarded by the traditional anti-collision algorithm.In addition,physical layer network coding is exploited by PNBA to obtain unread tag information through the decoding operation of physical layer network coding using the conflicting information in the stack.Therefore,PNBA reduces the number of interactions between reader and tags,and improves the tags identification efficiency.Theoretical analysis and simulation results using MATLAB demonstrate that PNBA reduces the number of readings,and improve RFID identification efficiency.Especially,when the number of tags to be identified is 100,the average needed reading number of PNBA is 83%lower than the basic binary search tree algorithm,43%lower than reverse binary search tree algorithm,and its reading efficiency reaches 0.93.展开更多
BACKGROUND The efficacy and safety of transarterial chemoembolization(TACE)combined with lenvatinib plus programmed cell death protein-1(PD-1)for unresectable hepato-cellular carcinoma(HCC)have rarely been evaluated a...BACKGROUND The efficacy and safety of transarterial chemoembolization(TACE)combined with lenvatinib plus programmed cell death protein-1(PD-1)for unresectable hepato-cellular carcinoma(HCC)have rarely been evaluated and it is unknown which factors are related to efficacy.AIM To evaluate the efficacy and independent predictive factors of TACE combined with lenvatinib plus PD-1 inhibitors for unresectable HCC.METHODS This study retrospectively enrolled patients with unresectable HCC who received TACE/lenvatinib/PD-1 treatment between March 2019 and April 2022.Overall survival(OS)and progression-free survival(PFS)were determined.The objective response rate(ORR)and disease control rate(DCR)were evaluated in accordance with the modified Response Evaluation Criteria in Solid Tumors.Additionally,the prognostic factors affecting the clinical outcome were assessed.RESULTS One hundred and two patients were enrolled with a median follow-up duration of 12.63 months.The median OS was 26.43 months(95%CI:17.00-35.87),and the median PFS was 10.07 months(95%CI:8.50-11.65).The ORR and DCR were 61.76%and 81.37%,respectively.The patients with Barcelona Clinic Liver Cancer Classification(BCLC)B stage,early neutrophil-to-lymphocyte ratio(NLR)response(decrease),or early alpha-fetoprotein(AFP)response(decrease>20%)had superior OS and PFS than their counterparts.CONCLUSION This study showed that TACE/lenvatinib/PD-1 treatment was well tolerated with encouraging efficacy in patients with unresectable HCC.The patients with BCLC B-stage disease with early NLR response(decrease)and early AFP response(decrease>20%)may achieve better clinical outcomes with this triple therapy.展开更多
An RF-UCard system is a contactless smartcard system with multiple chip operating systems and multiple applications. A multi-card collision occurs when more than one card within the reader’s read field and thus lower...An RF-UCard system is a contactless smartcard system with multiple chip operating systems and multiple applications. A multi-card collision occurs when more than one card within the reader’s read field and thus lowers the efficiency of the system. This paper presents a novel and enhanced algorithm to solve the multi-card collision problems in an RF-UCard system. The algorithm was originally inspired from framed ALOHA-based anti-collision algorithms applied in RFID systems. To maximize the system efficiency, a synchronous dynamic adjusting (SDA) scheme that adjusts both the frame size in the reader and the response probability in cards is developed and evaluated. Based on some mathematical results derived from the Poisson process and the occupancy problem, the algorithm takes the estimated card quantity and the new arriving cards in the current read cycle into consideration to adjust the frame size for the next read cycle. Also it changes the card response probability according to the request commands sent from the reader. Simulation results show that SDA outperforms other ALOHA-based anti-collision algorithms applied in RFID systems.展开更多
基金supported in part by National Natural Science Foundation of China(U22B2004,62371106)in part by the Joint Project of China Mobile Research Institute&X-NET(Project Number:2022H002)+6 种基金in part by the Pre-Research Project(31513070501)in part by National Key R&D Program(2018AAA0103203)in part by Guangdong Provincial Research and Development Plan in Key Areas(2019B010141001)in part by Sichuan Provincial Science and Technology Planning Program of China(2022YFG0230,2023YFG0040)in part by the Fundamental Enhancement Program Technology Area Fund(2021-JCJQ-JJ-0667)in part by the Joint Fund of ZF and Ministry of Education(8091B022126)in part by Innovation Ability Construction Project for Sichuan Provincial Engineering Research Center of Communication Technology for Intelligent IoT(2303-510109-04-03-318020).
文摘When the radio frequency identification(RFID)system inventories multiple tags,the recognition rate will be seriously affected due to collisions.Based on the existing dynamic frame slotted Aloha(DFSA)algorithm,a sub-frame observation and cyclic redundancy check(CRC)grouping combined dynamic framed slotted Aloha(SUBF-CGDFSA)algorithm is proposed.The algorithm combines the precise estimation method of the quantity of large-scale tags,the large-scale tags grouping mechanism based on CRC pseudo-randomcharacteristics,and the Aloha anti-collision optimization mechanism based on sub-frame observation.By grouping tags and sequentially identifying themwithin subframes,it accurately estimates the number of remaining tags and optimizes frame length accordingly to improve efficiency in large-scale RFID systems.Simulation outcomes demonstrate that this proposed algorithmcan effectively break through the system throughput bottleneck of 36.8%,which is up to 30%higher than the existing DFSA standard scheme,and has more significant advantages,which is suitable for application in largescale RFID tags scenarios.
基金supported by Canada First Research Excellence Fund,Medicine by Design(to CMM)。
文摘Over the last two decades,the dogma that cell fate is immutable has been increasingly challenged,with important implications for regenerative medicine.The brea kth rough discovery that induced pluripotent stem cells could be generated from adult mouse fibroblasts is powerful proof that cell fate can be changed.An exciting extension of the discovery of cell fate impermanence is the direct cellular reprogram ming hypothesis-that terminally differentiated cells can be reprogrammed into other adult cell fates without first passing through a stem cell state.
基金supported by National Institute on Aging(NIH-NIA)R21 AG074152(to KMA)National Institute of Allergy and Infectious Diseases(NIAID)grant DP2 AI171150(to KMA)Department of Defense(DoD)grant AZ210089(to KMA)。
文摘The brain's extracellular matrix(ECM),which is comprised of protein and glycosaminoglycan(GAG)scaffolds,constitutes 20%-40% of the human brain and is considered one of the largest influencers on brain cell functioning(Soles et al.,2023).Synthesized by neural and glial cells,the brain's ECM regulates a myriad of homeostatic cellular processes,including neuronal plasticity and firing(Miyata et al.,2012),cation buffering(Moraws ki et al.,2015),and glia-neuron interactions(Anderson et al.,2016).Considering the diversity of functions,dynamic remodeling of the brain's ECM indicates that this understudied medium is an active participant in both normal physiology and neurological diseases.
文摘Objective:To explore the perspectives of high-risk pregnant women regarding the home care program for high-risk pregnancies.Methods:This qualitative study was conducted in a university hospital and 5 comprehensive health centers in Ahvaz,Iran,from February 2023 to July 2023.The sampling method used was purposive sampling considering the maximum possible diversity,which continued until data saturation.11 in-depth and semistructured interviews were conducted with high-risk pregnant women.Data were simultaneously analysed using Graneheim and Lundman content analysis by MAXQDA version 20 software.Results:Data analysis extracted 3 themes,12 categories,and 26 subcategories.The themes and categories were“high-risk pregnancy and related issues(pursuing treatment and paying attention to the high-risk situation by pregnant women,psychological aspect of high-risk pregnancy on pregnant women and caregivers,emotional and physical aspects of high-risk pregnancy,the consequences of high-risk pregnancy on the people around them and empowerment of high-risk pregnant women)”,“support dimension(family and community support for high-risk pregnant women)”,and“framework of program(acculturalization,means and equipment,security,manpower and the necessary arrangements for the home care)”.Conclusions:High-risk pregnancy affects various aspects of the lives of high-risk pregnant women and their families.Creating the necessary conditions for providing care at home plays a vital role in supporting high-risk pregnant women and removing related obstacles to receiving prenatal care in person.It will be especially beneficial for high-risk pregnant women in low-income areas.
基金Supported by Longtian Town Rural Science and Technology Specialists Team for Rural Revitalization in Guangdong Province (2021)Huizhou Philosophy and Social Science Planning Project (HZSK2024GJ120).
文摘This study focuses on"Longxuhuang",a fresh agricultural product from Longtian Town in Longmen County.By establishing the objectives of brand promotion and analyzing the appropriate promotional channels,we aim to effectively position the brand,cultivate a promotional atmosphere,identify suitable channels for promotion,anticipate potential risks,and propose corresponding countermeasures.Additionally,we assess the effectiveness of the promotional strategies employed.The findings of this research will contribute to the brand promotion of enterprises and offer insights for the brand promotion of agricultural products in other regions.
基金Supported by Jilin Provincial Natural Science Foundation,No.YDZJ202401650ZYTS。
文摘This editorial discusses Christodoulidis et al's article,which appeared in the most recent edition.The clinical trials have demonstrated the programmed cell death receptor 1(PD-1)inhibitor Pembrolizumab involved combination therapy can improve the efficacy of advanced gastric cancer(AGC).Pembrolizumab combined with chemotherapy can enhance its sensitivity,and further eliminate tumor cells that develop resistance to chemotherapy.The combination of Pembrolizumab and Trastuzumab targeting human epidermal growth factor receptor 2 showed improved prognosis.The overall toxic effects of Pembrolizumab are significantly lower than traditional chemotherapy,and the safety is controllable.PD-1 inhibitor Pembrolizumab sheds a light on the treatment of AGC and brings new hope to the clinical practice.
文摘BACKGROUND Immune checkpoint inhibitors(ICIs)are a new class of antitumor agents.They enhance antitumor effects by blocking inhibitory receptors and related ligands expressed on T cells.ICIs also modulate regular immune cell activity,affecting the immune system and causing immune-related adverse events.The renal system is sometimes affected by these adverse events.Currently,the literature on ICIs-related glomerular injuries is scarce.CASE SUMMARY We present a patient who developed granulomatosis with polyangiitis(GPA)3 weeks after treatment with the anti-programmed cell death-1 inhibitor,tislel-izumab.The patient experienced proteinuria,hematuria,and acute kidney injury without pulmonary hemorrhage and tested positive for anti-neutrophil cyto-plasmic antibody(ANCA)-cytoplasmic type.Renal biopsy confirmed ANCA-associated vasculitis,and GPA was finally diagnosed.The patient received pulse treatment with glucocorticoids and cyclophosphamide,and renal function improved.After self-discontinuation of the drug,the disease recurred,and the original treatment regimen was continued.However,the patient’s renal function continued to deteriorate.CONCLUSION Glucocorticoids plus cyclophosphamide are effective for treating GPA induced by tislelizumab.However,follow-up and patient education are needed.
基金This work is supported by the National Natu ral Science Foundation of China under grant No.61071073 and No. 61371092, Doctoral Fund of Ministry of Education of China (No.20090061110043).
文摘A novel anti-collision algorithm in RFID wireless network is proposed.As it is put forward on the basis of collision tree(CT)and improved collision tree(lCT) anti-collision protocols,we call it adaptive collision tree protocol(ACT).The main novelty of this paper is that the AD strategy is introduced and used in ACT to decrease collisions and improve the tag system throughput.AD strategy means that query strings will divide into two or four branches adaptively according to the label quantity.This scheme can decrease both depth of query and collision timeslots,and avoid producing too much idle timeslots at the same time.Both theoretical analysis and simulation results indicate that the novel proposed anticollision protocol ACT outperforms the previous CT and ICT protocols in term of time complexity,system throughput,and communication complexity.
基金supported by National Basic Research Program of China(973 Program, No.2010CB327403)
文摘Collision and security issues are considered as barriers to RFID applications.In this paper,a parallelizable anti-collision based on chaotic sequence combined dynamic frame slotted aloha to build a high-efficiency RFID system is proposed.In the tags parallelizable identification,we design a Discrete Markov process to analyze the success identification rate.Then a mutual authentication security protocol merging chaotic anti-collision is presented.The theoretical analysis and simulation results show that the proposed identification scheme has less than 45.1%of the identification time slots compared with the OVSF-system when the length of the chaos sequence is 31.The success identification rate of the proposed chaotic anti-collision can achieve 63%when the number of the tag is100.We test the energy consumption of the presented authentication protocol,which can simultaneously solve the anti-collision and security of the UHF RFID system.
基金This work was supported in part by the National Natural Science Foundation of China under project contracts[NOS.61601093,61791082,61701116,61371047]in part by Sichuan Provincial Science and Technology Planning Program of China under project contracts No.2016GZ0061 and No.2018HH0044+2 种基金in part by Guangdong Provincial Science and Technology Planning Program of China under project contracts No.2015B090909004 and No.2016A010101036in part by the fundamental research funds for the Central Universities under project contract No.ZYGX2016Z011in part by Science and Technology on Electronic Information Control Laboratory.
文摘A priori knowledge of the number of tags is crucial for anti-collision protocols in slotted UHF RFID systems.The number of tags is used to decide optimal frame length in dynamic frame slotted ALOHA(DFSA)and to adjust access probability in random access protocols.Conventional researches estimate the number of tags in MAC layer based on statistics of empty slots,collided slots and successful slots.Usually,a collision detection algorithm is employed to determine types of time slots.Only three types are distinguished because of lack of ability to detect the number of tags in single time slot.In this paper,a physical layer algorithm is proposed to detect the number of tags in a collided slot.Mean shift algorithm is utilized,and some properties of backscatter signals are investigated.Simulation results verify the effectiveness of the proposed solution in terms of low estimation error with a high SNR range,outperforming the existing MAC layer approaches.
文摘Recently,object identification with radio frequency identification(RFID)technology is becoming increasingly popular.Identification time is a key performance metric to evaluate the RFID system.The present paper analyzes the deficiencies of the state-of-the-arts algorithms and proposes a novel sub-frame-based algorithm with adaptive frame breaking policy to lower the tag identification time for EPC global C1 Gen2 UHF RFID standard.Through the observation of slot statistics in a sub-frame,the reader estimates the tag quantity and efficiently calculates an optimal frame size to fit the unread tags.Only when the expected average identification time in the calculated frame size is less than that in the previous frame size,the reader starts the new frame.Moreover,the estimation of the proposed algorithm is implemented by the look-up tables,which allows dramatically reduction in the computational complexity.Simulation results show noticeable throughput and time efficiency improvements of the proposed solution over the existing approaches.
基金This work was partially supported by the Key-Area Research and Development Program of Guangdong Province(2019B010136001,20190166)the Basic and Applied Basic Research Major Program for Guangdong Province(2019B030302002)the Science and Technology Planning Project of Guangdong Province LZC0023 and LZC0024.
文摘Radio frequency identification(RFID)has been widespread used in massive items tagged domains.However,tag collision increases both time and energy consumption of RFID network.Tag collision can seriously affect the success of tag identification.An efficient anti-collision protocol is very crucially in RFID system.In this paper,an improved binary search anti-collision protocol namely BRTP is proposed to cope with the tag collision concern,which introduces a Bi-response mechanism.In Bi-response mechanism,two groups of tags allowed to reply to the reader in the same slot.According to Bi-response mechanism,the BRTP strengthens the tag identification of RFID network by reducing the total number of queries and exchanged messages between the reader and tags.Both theoretical analysis and numerical results verify the effectiveness of the proposed BRTP in various performance metrics including the number of total slots,system efficiency,communication complexity and total identification time.The BRTP is suitable to be applied in passive RFID systems.
基金Supported by the National Natural Science Foundation of China(No.61401407)
文摘Due to more tag-collisions result in failed transmissions,tag anti-collision is a very vital issue in the radio frequency identification(RFID) system.However,so far decreases in communication time and increases in throughput are very limited.In order to solve these problems,this paper presents a novel tag anti-collision scheme,namely adaptive hybrid search tree(AHST),by combining two algorithms of the adaptive binary-tree disassembly(ABD) and the combination query tree(CQT),in which ABD has superior tag identification velocity and CQT has optimum performance in system throughput and search timeslots.From the theoretical analysis and numerical simulations,the proposed algorithm can colligate the advantages of above algorithms,improve the system throughput and reduce the searching timeslots dramatically.
文摘In this paper, we develop a novel mathematical model to estimate the probability distribution function of the number of tags discovered after a certain number of interrogation rounds. In addition, the pdfs of the number of rounds needed to discover all the tags are also calculated. The estimation of such pdfs will be helpful in estimating the number of interrogation rounds and the optimal parameter configuration of the RFID system which in turn will be helpful in estimating the time needed to discover all tags. Our results show that the proposed model accurately predicts the tags detection probability. We then use the proposed model to optimally configure the reader parameters (i.e. the frame size and the number of interrogation rounds).
文摘Auto anti-collision technology is one of the main research subjects of automobiles’ safety technology. Aiming at the key technology of Auto anti-collision, measuring the distance from obstacles, based on the theory of phase laser distance ranging, Laser Diode (LD) distance-measuring system for auto anti-collision has been developed to solve the problem of on-line measuring distance technology in middle to long distance utilizing the good characteristics of LD when modulating its optical intensity and adopting typical kinds of filter techniques in this paper. By theoretical analysis, adopting typical kinds of filter techniques can reduce the interference of strong light, so distance-measuring range can be 0.5–100 m in daytime or 1–200 m at night. And more, from theoretical analysis and experiment result, it can guarantee the high measuring resolution which can be less than 24.5 mm, utilizing the method of two Laser Diode optical intensity modulating wavelength and complimenting precise calibration and revision. The idea of LD distance-measuring technology is novel and feasible and this technology can be applied in Auto anti-collision. Key words laser diode - phase laser distance ranging - filter techniques - auto anti-collision CLC number TH 161 Foundation item: Supported by the National Natural Science Foundation of China (59675080, 59805006) and Wuhan Chenguang Foundation (20025001001)Biography: Zhang Xin-bao (1965-), male, Associate professor, research direction: precise mechanism and instrument.
文摘Multi-tag collision imposes a vital detrimental effect on reading performanceof an RFID system. In order to ameliorate such collision problem and to improve thereading performance, this paper proposes an efficient tag identification algorithm termedas the Enhanced Adaptive Tree Slotted Aloha (EATSA). The key novelty of EATSA is toidentify the tags using grouping strategy. Specifically, the whole tag set is divided intogroups by a frame of size F. In cases multiple tags fall into a group, the tags of the groupare recognized by the improved binary splitting (IBS) method whereas the rest tags arewaiting in the pipeline. In addition, an early observation mechanism is introduced toupdate the frame size to an optimum value fitting the number of tags. Theoretical analysisand simulation results show that the system throughput of our proposed algorithm canreach as much as 0.46, outperforming the prior Aloha-based protocols.
基金The authors received funding for this study from the National Key R&D Program(https://chinainnovationfunding.eu/national-key-rd-programmes/),project contract No.2018YFB1802102(G.W.)and 2018AAA0103203(W.T,F.X,G.W.)from the National Natural Science Foundation of China(https://www.nsfc.gov.cn/),project contracts No.61971113(G.W.)and 61901095(D.I.)+6 种基金from the Guangdong Provincial Research and Development Plan in Key Areas(https://chinainnovationfunding.eu/funding-programmes-guangdong-province-2/)project contracts No.2019B010141001(G.W.)and 2019B010142001(G.W.)from the Sichuan Provincial Science and Technology Planning Program(https://www.sc.gov.cn/10462/10758/10759/10763/2010/10/28/10147629.shtml)project contracts No.2020YFG0039(G.W.),2021YFG0013(G.W.),and 2021YFH0133(D.I.)from the Ministry of Education(http://en.moe.gov.cn/)and China Mobile(http://www.chinamobileltd.com)Joint Fund Program,project contract No.MCM20180104(G.W.,G.L.)from the fundamental research funds for the Central Universities(managed by Department of Finance,https://www.fmprc.gov.cn/mfa_eng/wjb_663304/zzjg_663340/cws_665320/)project contract no.YGX2019Z022(G.W.,G.L.,D.I.).
文摘In this paper,a dynamic multi-ary query tree(DMQT)anti-collision protocol for Radio Frequency Identification(RFID)systems is proposed for large scale passive RFID tag identification.The proposed DMQT protocol is based on an iterative process between the reader and tags which identifies the position of collision bits through map commands and dynamically encodes them to optimize slots allocation through query commands.In this way,the DMQT completely eliminates empty slots and greatly reduces collision slots,which in turn reduces the identification time and energy costs.In addition and differently to other known protocols,the DMQT does not need to estimate the number of tags,reducing the protocol implementation complexity and eliminating the uncertainty caused by the estimation algorithm.A numerical analysis shows that DMQT has better performance than other algorithms for a number of tags larger than 300.Meanwhile,when the number of tags is 2000 and the tag identity(ID)length is 128 bits,the total identification time is 2.58 s and the average energy cost for a tag identification is 1.2 mJ,which are 16.9%and 10.4%less than those of state-of-the-art algorithms,respectively.In addition,a DMQT extension based on ACK command has also been presented to deal with capture effect and avoid missing identification.
基金the National Natural Science Foundation of China under Grant 61502411Natural Science Foundation of Jiangsu Province under Grant BK20150432 and BK20151299+7 种基金Natural Science Research Project for Universities of Jiangsu Province under Grant 15KJB520034China Postdoctoral Science Foundation under Grant 2015M581843Jiangsu Provincial Qinglan ProjectTeachers Overseas Study Program of Yancheng Institute of TechnologyJiangsu Provincial Government Scholarship for Overseas StudiesTalents Project of Yancheng Institute of Technology under Grant KJC2014038“2311”Talent Project of Yancheng Institute of TechnologyOpen Fund of Modern Agricultural Resources Intelligent Management and Application Laboratory of Huzhou Normal University.
文摘In RFID(Radio Frequency IDentification)system,when multiple tags are in the operating range of one reader and send their information to the reader simultaneously,the signals of these tags are superimposed in the air,which results in a collision and leads to the degrading of tags identifying efficiency.To improve the multiple tags’identifying efficiency due to collision,a physical layer network coding based binary search tree algorithm(PNBA)is proposed in this paper.PNBA pushes the conflicting signal information of multiple tags into a stack,which is discarded by the traditional anti-collision algorithm.In addition,physical layer network coding is exploited by PNBA to obtain unread tag information through the decoding operation of physical layer network coding using the conflicting information in the stack.Therefore,PNBA reduces the number of interactions between reader and tags,and improves the tags identification efficiency.Theoretical analysis and simulation results using MATLAB demonstrate that PNBA reduces the number of readings,and improve RFID identification efficiency.Especially,when the number of tags to be identified is 100,the average needed reading number of PNBA is 83%lower than the basic binary search tree algorithm,43%lower than reverse binary search tree algorithm,and its reading efficiency reaches 0.93.
文摘BACKGROUND The efficacy and safety of transarterial chemoembolization(TACE)combined with lenvatinib plus programmed cell death protein-1(PD-1)for unresectable hepato-cellular carcinoma(HCC)have rarely been evaluated and it is unknown which factors are related to efficacy.AIM To evaluate the efficacy and independent predictive factors of TACE combined with lenvatinib plus PD-1 inhibitors for unresectable HCC.METHODS This study retrospectively enrolled patients with unresectable HCC who received TACE/lenvatinib/PD-1 treatment between March 2019 and April 2022.Overall survival(OS)and progression-free survival(PFS)were determined.The objective response rate(ORR)and disease control rate(DCR)were evaluated in accordance with the modified Response Evaluation Criteria in Solid Tumors.Additionally,the prognostic factors affecting the clinical outcome were assessed.RESULTS One hundred and two patients were enrolled with a median follow-up duration of 12.63 months.The median OS was 26.43 months(95%CI:17.00-35.87),and the median PFS was 10.07 months(95%CI:8.50-11.65).The ORR and DCR were 61.76%and 81.37%,respectively.The patients with Barcelona Clinic Liver Cancer Classification(BCLC)B stage,early neutrophil-to-lymphocyte ratio(NLR)response(decrease),or early alpha-fetoprotein(AFP)response(decrease>20%)had superior OS and PFS than their counterparts.CONCLUSION This study showed that TACE/lenvatinib/PD-1 treatment was well tolerated with encouraging efficacy in patients with unresectable HCC.The patients with BCLC B-stage disease with early NLR response(decrease)and early AFP response(decrease>20%)may achieve better clinical outcomes with this triple therapy.
文摘An RF-UCard system is a contactless smartcard system with multiple chip operating systems and multiple applications. A multi-card collision occurs when more than one card within the reader’s read field and thus lowers the efficiency of the system. This paper presents a novel and enhanced algorithm to solve the multi-card collision problems in an RF-UCard system. The algorithm was originally inspired from framed ALOHA-based anti-collision algorithms applied in RFID systems. To maximize the system efficiency, a synchronous dynamic adjusting (SDA) scheme that adjusts both the frame size in the reader and the response probability in cards is developed and evaluated. Based on some mathematical results derived from the Poisson process and the occupancy problem, the algorithm takes the estimated card quantity and the new arriving cards in the current read cycle into consideration to adjust the frame size for the next read cycle. Also it changes the card response probability according to the request commands sent from the reader. Simulation results show that SDA outperforms other ALOHA-based anti-collision algorithms applied in RFID systems.