The moon jellyfi sh Aurelia spp.is a worldwide distributed scyphozoan species that seasonally blooms in coastal waters.Although the strobilation is directly responsible for the scale of jellyfi sh bloom,the underlying...The moon jellyfi sh Aurelia spp.is a worldwide distributed scyphozoan species that seasonally blooms in coastal waters.Although the strobilation is directly responsible for the scale of jellyfi sh bloom,the underlying mechanisms remain largely unknown.We exposed Aurelia coerulea polyps to 18 bioactive substances to test their ability to induce strobilation at the natural typically non-strobilation temperature of 21°C.Results revealed that A.coerulea polyps responded in four types.Type I—no change for estradiol,folic acid,iodine,retinoic acid,serotonin hydrochloride,and vitamin A.We suggested that 5-aza-2-deoxycytidine and N-acetyl-L-glutamic acid could not induce strobilation,since the percent of strobilated polyps in these two substances treatments was 3.3%and 1%,respectively.Type II—polyp body elongation for 3,5-diiodo-Ltyrosine,indole-3-acetic acid,L-dopamine,and noradrenaline treatments.Type III—transverse constrictions for L-thyroxine,progesterone,and melatonin treatments.Finally,Type IV—complete strobilation for 5-methoxy-2-methylindole,acetylcholine chloride,and indomethacin treatments,where the pre-strobilation periods were 2,4,and 2 days,and the mean numbers of ephyrae released per strobila were 4.7,5.7,and 5.7,respectively.The results reveal that indole derivatives,which contained methoxy or methyl pharmacophore,were the common strobilation inducer in the genus Aurelia.Iodinated organic compounds,catecholamine,acetylcholine chloride,and retinoic acid are species-specifi c strobilation inducer.Therefore,A.coerulea strobilation is regulated by neuronal and endocrine processes.Our fi ndings provide clues in understanding the mechanism of strobilation and contribute to developing specifi c strobilation antagonists in controlling moon jellyfi sh blooms.展开更多
Okra （Abelmoschus esculentus L. ） is a novel heahhcare vegetable that has been developed rapidly in recent years in China. It contains abundant bioactive substances with significant heahbeare functions. So far, many...Okra （Abelmoschus esculentus L. ） is a novel heahhcare vegetable that has been developed rapidly in recent years in China. It contains abundant bioactive substances with significant heahbeare functions. So far, many domestic research institutions have carried out researches about the extraction technology of bioactive substances and their heahhcare functions. At present, tender pods and other organs of A. esculentus are mainly used freshly and directly, but rare products have been processed and developed. In this paper, the research progress of bioactive substances and processing ofA. esculentus was summarized, aiming at providing reference for the deep processing and comprehensive utilization of A. escu/entus in the future in China.展开更多
为了对发酵桑叶茶工艺条件进行优化并探究桑叶茶经发酵后抗氧化活性的变化,该试验通过响应面分析法确定发酵桑叶茶在发酵温度、发酵时间和黑曲霉接种量3种变量条件下的最佳工艺条件,并测定发酵桑叶茶生物活性物质含量及其抗氧化性。结...为了对发酵桑叶茶工艺条件进行优化并探究桑叶茶经发酵后抗氧化活性的变化,该试验通过响应面分析法确定发酵桑叶茶在发酵温度、发酵时间和黑曲霉接种量3种变量条件下的最佳工艺条件,并测定发酵桑叶茶生物活性物质含量及其抗氧化性。结果表明,最佳工艺条件为发酵时间5 d 16 h,发酵温度30℃,接种量16.55%,此条件下所制发酵桑叶茶感官评分高达90分,且其总黄酮、总多糖、多酚、游离氨基酸、芦丁、槲皮素含量比桑叶绿茶分别升高了14.39%、12.67%、2.90%、3.46%、81.13%、19.35%,还检测到了含量7.55%±0.37%的茶褐素。此外,1/1000(g/mL)浓度下发酵桑叶茶对羟基自由基、DPPH自由基、超氧自由基的清除率和对二价铁离子的螯合率分别是桑叶绿茶的1.16倍、1.07倍、1.06倍和0.82倍,该研究结果为今后桑叶的进一步开发与应用提供理论基础和参考。展开更多
Ganoderma lucidum is a Chinese medicinal fungus with a long history of use in healthcare and disease treatment.G.lucidum spores(GLS)are tiny germ cells released from the mushroom cap during the mature stage of growth....Ganoderma lucidum is a Chinese medicinal fungus with a long history of use in healthcare and disease treatment.G.lucidum spores(GLS)are tiny germ cells released from the mushroom cap during the mature stage of growth.They contain all the genetic active substances of G.lucidum.G.lucidum spore oil(GLSO)is a lipid component extracted from broken-walled Ganoderma spores using supercritical CO_(2)extraction technology.GLSO contains fatty acids,Ganoderma triterpenes,sterols and other bioactive compounds.Previous studies have demonstrated that GLSO has a wide range of pharmacological properties,including anti-tumor,anti-aging,neuroprotection,immunomodulation,hepatoprotection and modulation of metabolic diseases.This review summarizes the research progress of GLSO over the past two decades in terms of its bioactive components,extraction and processing techniques,pharmacological effects and safety evaluation.This provides a solid foundation for further research and application of GLSO.展开更多
基金Supported by the National Key R&D Program of China(No.2017YFC1404401)the National Natural Science Foundation of China(Nos.41606127,41976135)the Youth Talent Support Program of the Laboratory for Marine Ecology and Environmental Science,Pilot National Laboratory for Marine Science and Technology(Qingdao)(No.LMEESYTSP-2018-01-10)。
文摘The moon jellyfi sh Aurelia spp.is a worldwide distributed scyphozoan species that seasonally blooms in coastal waters.Although the strobilation is directly responsible for the scale of jellyfi sh bloom,the underlying mechanisms remain largely unknown.We exposed Aurelia coerulea polyps to 18 bioactive substances to test their ability to induce strobilation at the natural typically non-strobilation temperature of 21°C.Results revealed that A.coerulea polyps responded in four types.Type I—no change for estradiol,folic acid,iodine,retinoic acid,serotonin hydrochloride,and vitamin A.We suggested that 5-aza-2-deoxycytidine and N-acetyl-L-glutamic acid could not induce strobilation,since the percent of strobilated polyps in these two substances treatments was 3.3%and 1%,respectively.Type II—polyp body elongation for 3,5-diiodo-Ltyrosine,indole-3-acetic acid,L-dopamine,and noradrenaline treatments.Type III—transverse constrictions for L-thyroxine,progesterone,and melatonin treatments.Finally,Type IV—complete strobilation for 5-methoxy-2-methylindole,acetylcholine chloride,and indomethacin treatments,where the pre-strobilation periods were 2,4,and 2 days,and the mean numbers of ephyrae released per strobila were 4.7,5.7,and 5.7,respectively.The results reveal that indole derivatives,which contained methoxy or methyl pharmacophore,were the common strobilation inducer in the genus Aurelia.Iodinated organic compounds,catecholamine,acetylcholine chloride,and retinoic acid are species-specifi c strobilation inducer.Therefore,A.coerulea strobilation is regulated by neuronal and endocrine processes.Our fi ndings provide clues in understanding the mechanism of strobilation and contribute to developing specifi c strobilation antagonists in controlling moon jellyfi sh blooms.
基金Supported by Youth Scientific Research Fund of Shandong Academy of Agricultural Sciences(2014QNM55)
文摘Okra （Abelmoschus esculentus L. ） is a novel heahhcare vegetable that has been developed rapidly in recent years in China. It contains abundant bioactive substances with significant heahbeare functions. So far, many domestic research institutions have carried out researches about the extraction technology of bioactive substances and their heahhcare functions. At present, tender pods and other organs of A. esculentus are mainly used freshly and directly, but rare products have been processed and developed. In this paper, the research progress of bioactive substances and processing ofA. esculentus was summarized, aiming at providing reference for the deep processing and comprehensive utilization of A. escu/entus in the future in China.
文摘为了对发酵桑叶茶工艺条件进行优化并探究桑叶茶经发酵后抗氧化活性的变化,该试验通过响应面分析法确定发酵桑叶茶在发酵温度、发酵时间和黑曲霉接种量3种变量条件下的最佳工艺条件,并测定发酵桑叶茶生物活性物质含量及其抗氧化性。结果表明,最佳工艺条件为发酵时间5 d 16 h,发酵温度30℃,接种量16.55%,此条件下所制发酵桑叶茶感官评分高达90分,且其总黄酮、总多糖、多酚、游离氨基酸、芦丁、槲皮素含量比桑叶绿茶分别升高了14.39%、12.67%、2.90%、3.46%、81.13%、19.35%,还检测到了含量7.55%±0.37%的茶褐素。此外,1/1000(g/mL)浓度下发酵桑叶茶对羟基自由基、DPPH自由基、超氧自由基的清除率和对二价铁离子的螯合率分别是桑叶绿茶的1.16倍、1.07倍、1.06倍和0.82倍,该研究结果为今后桑叶的进一步开发与应用提供理论基础和参考。
基金supported by Pearl River S&T Nova Program of Guangzhou(No.201610010113)the Open Research Fund of NMPA Key Laboratory for Rapid Testing Technology of Drugs,Guangdong Institute for Drug Control(No.KF2022002,KF2022006)Research Project of Chinese Medicine in TCM Bureau of Guangdong Province(No.20231202).
文摘Ganoderma lucidum is a Chinese medicinal fungus with a long history of use in healthcare and disease treatment.G.lucidum spores(GLS)are tiny germ cells released from the mushroom cap during the mature stage of growth.They contain all the genetic active substances of G.lucidum.G.lucidum spore oil(GLSO)is a lipid component extracted from broken-walled Ganoderma spores using supercritical CO_(2)extraction technology.GLSO contains fatty acids,Ganoderma triterpenes,sterols and other bioactive compounds.Previous studies have demonstrated that GLSO has a wide range of pharmacological properties,including anti-tumor,anti-aging,neuroprotection,immunomodulation,hepatoprotection and modulation of metabolic diseases.This review summarizes the research progress of GLSO over the past two decades in terms of its bioactive components,extraction and processing techniques,pharmacological effects and safety evaluation.This provides a solid foundation for further research and application of GLSO.
